fluorouracil has been researched along with Cholangioma in 24 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A phase II trial of the regimen 5-fluorouracil, doxorubicin, and mitomycin C (FAM) was conducted in 17 patients with advanced or recurrent biliary tract cancer." | 3.67 | 5-Fluorouracil, mitomycin, and doxorubicin (FAM) in carcinoma of the biliary tract. ( Harvey, JH; Schein, PS; Smith, FP, 1984) |
| " Thus, both intraarterial and intraportal chemotherapy combined with decollateralization by silicone rubber sheeting seems to be effective for advanced cholangiocarcinoma and metastatic carcinoma." | 1.28 | [Intraarterial and intraportal chemotherapy combined with decollateralization for cholangiocellular carcinoma and metastatic liver cancer]. ( Fukuda, I; Furukawa, H; Imaoka, S; Ishikawa, O; Masutani, S; Nagano, H; Ohashi, I; Oohigashi, H; Sasaki, Y; Yasuda, T, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (79.17) | 18.7374 |
| 1990's | 5 (20.83) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Falkson, G | 3 |
| MacIntyre, JM | 1 |
| Moertel, CG | 2 |
| Johnson, LA | 1 |
| Scherman, RC | 1 |
| Smith, GW | 1 |
| Bukowski, RM | 2 |
| Hewlett, JS | 2 |
| Groppe, CW | 2 |
| Harvey, JH | 1 |
| Smith, FP | 1 |
| Schein, PS | 1 |
| Hashmonai, M | 1 |
| Lev, L | 1 |
| Schramek, A | 1 |
| Ben-Arieh, Y | 1 |
| Robinson, E | 1 |
| Beals, SP | 1 |
| Lucas, RJ | 1 |
| Niederhuber, JE | 1 |
| Ensminger, WD | 1 |
| Kelm, C | 1 |
| Henneking, K | 1 |
| Zimmermann, T | 1 |
| Vollerthun, M | 1 |
| Padberg, W | 1 |
| Ravikumar, TS | 1 |
| Pizzorno, G | 1 |
| Bodden, W | 1 |
| Marsh, J | 1 |
| Strair, R | 1 |
| Pollack, J | 1 |
| Hendler, R | 1 |
| Hanna, J | 1 |
| D'Andrea, E | 1 |
| McBride, CM | 1 |
| Umsawasdi, T | 1 |
| Chainuvati, T | 1 |
| Hitanant, S | 1 |
| Nilprabhassorn, P | 1 |
| Viranuvatti, V | 1 |
| Seligman, M | 1 |
| Weick, JK | 1 |
| Greenstreet, RL | 1 |
| Lavin, P | 1 |
| Pretorius, FJ | 1 |
| Carbone, PP | 1 |
| Ettinger, DS | 1 |
| Dragon, LH | 1 |
| Klein, J | 1 |
| Sgagias, M | 1 |
| Order, SE | 1 |
| Buskirk, SJ | 1 |
| Gunderson, LL | 1 |
| Schild, SE | 1 |
| Bender, CE | 1 |
| Williams, HJ | 1 |
| McIlrath, DC | 1 |
| Robinow, JS | 1 |
| Tremaine, WJ | 1 |
| Martin, JK | 1 |
| Tsushima, K | 1 |
| Sakata, Y | 1 |
| Shiratori, Y | 1 |
| Sakamoto, J | 1 |
| Koeda, J | 1 |
| Yamada, Y | 1 |
| Soma, N | 1 |
| Tamura, K | 1 |
| Yoshiwara, A | 1 |
| Soma, Y | 1 |
| Nagano, H | 2 |
| Sasaki, Y | 2 |
| Imaoka, S | 2 |
| Masutani, S | 1 |
| Ohashi, I | 1 |
| Ishikawa, O | 2 |
| Oohigashi, H | 1 |
| Yasuda, T | 1 |
| Furukawa, H | 2 |
| Fukuda, I | 2 |
| Maruyama, T | 1 |
| Koura, Y | 1 |
| Kurisu, Y | 1 |
| Kuroi, K | 1 |
| Kai, Y | 1 |
| Wada, H | 1 |
| Shibata, T | 1 |
| Ohigashi, H | 1 |
| Kabuto, T | 1 |
| Izumi, R | 1 |
| Urade, M | 1 |
| Kimura, H | 1 |
| Kobayashi, M | 1 |
| Yabushita, K | 1 |
| Watanabe, T | 1 |
| Fujimura, T | 1 |
| Ohhori, I | 1 |
| Itoh, M | 1 |
| Yonemura, Y | 1 |
| Takasaki, H | 1 |
| Uchida, Y | 1 |
| Shigemitsu, O | 1 |
| Oka, K | 1 |
| Mori, Y | 1 |
| Fujitomi, Y | 1 |
| Ichimanda, M | 1 |
| Shibata, O | 1 |
| Shirabe, J | 1 |
| Geddes, EW | 1 |
| Bessot, M | 1 |
| Duprez, A | 1 |
| Mauuary, G | 1 |
| Winsback, AM | 1 |
| Iwamura, K | 1 |
| al-Sarraf, M | 1 |
| Go, TS | 1 |
| Kithier, K | 1 |
| Vaitkevicius, VK | 1 |
3 trials available for fluorouracil and Cholangioma
| Article | Year |
|---|---|
Primary liver cancer. An Eastern Cooperative Oncology Group Trial.
Topics: Adenoma, Bile Duct; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Body W | 1984 |
Percutaneous hepatic vein isolation and high-dose hepatic arterial infusion chemotherapy for unresectable liver tumors.
Topics: Adenoma, Bile Duct; Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, | 1994 |
Chemotherapy studies in primary liver cancer: a prospective randomized clinical trial.
Topics: Adenoma, Bile Duct; Antineoplastic Agents; Bone Marrow; Carcinoma, Hepatocellular; Clinical Trials a | 1978 |
21 other studies available for fluorouracil and Cholangioma
| Article | Year |
|---|---|
Hepatic artery infusion of 5-fluorouracil and mitomycin C in cholangiocarcinoma and gallbladder carcinoma.
Topics: Adenoma, Bile Duct; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms | 1984 |
5-Fluorouracil, mitomycin, and doxorubicin (FAM) in carcinoma of the biliary tract.
Topics: Adenoma, Bile Duct; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neopl | 1984 |
Long survival following combined treatment of inoperable cholangiocarcinoma: surgery, radiotherapy, and chemotherapy.
Topics: Adenoma, Bile Duct; Bile Duct Neoplasms; Cobalt Radioisotopes; Cyclophosphamide; Drainage; Fluoroura | 1980 |
Management of high bile duct carcinoma.
Topics: Adenocarcinoma; Adenoma, Bile Duct; Aged; Bile Duct Neoplasms; Bile Ducts; Combined Modality Therapy | 1984 |
Surgical considerations in the management of hepatic neoplasia.
Topics: Adenoma, Bile Duct; Antineoplastic Agents; Carcinoma, Hepatocellular; Catheterization; Floxuridine; | 1983 |
[Palliative therapy of primary liver tumors].
Topics: Adenoma, Bile Duct; Adolescent; Adult; Aged; alpha-Fetoproteins; Angiography; Antineoplastic Combine | 1993 |
Primary carcinoma of the liver.
Topics: Adenoma, Bile Duct; Adolescent; Adult; Aged; Carcinoma; Carcinoma, Hepatocellular; Child; Child, Pre | 1976 |
Combination chemotherapy with 5--fluorouracil, amethopterin (methotrexate) and prednisolone (FAP protocol) in the therapy of cholangiocarcinoma.
Topics: Adenoma, Bile Duct; Drug Therapy, Combination; Fluorouracil; Humans; Liver Neoplasms; Male; Methotre | 1976 |
Chemotherapy of metastatic gastrointestinal neoplasms with 5-fluorouracil and streptozotocin.
Topics: Adenocarcinoma; Adenoma, Bile Duct; Adenoma, Islet Cell; Adult; Aged; Bile Duct Neoplasms; Carcinoid | 1977 |
Isotopic immunoglobulin in an integrated multimodal treatment program for a primary liver cancer: a case report.
Topics: Adenoma, Bile Duct; Adult; Carcinoembryonic Antigen; Doxorubicin; Drug Therapy, Combination; Female; | 1979 |
Analysis of failure after curative irradiation of extrahepatic bile duct carcinoma.
Topics: Adenoma, Bile Duct; Adult; Aged; Aged, 80 and over; Bile Duct Neoplasms; Combined Modality Therapy; | 1992 |
[Cases of advanced cholangiocarcinoma showing partial response by the combination chemotherapy including protracted continuous infusion of 5-FU combined with intravenous administration of low-dose leucovorin and intra-arterial administration of MMC and CQ
Topics: Adenoma, Bile Duct; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Carbazilqui | 1991 |
[Intraarterial and intraportal chemotherapy combined with decollateralization for cholangiocellular carcinoma and metastatic liver cancer].
Topics: Adenoma, Bile Duct; Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile | 1990 |
[Intra-arterial infusion chemotherapy in non-resectable pancreatic cancer using angiotensin-II and implantable drug delivery system].
Topics: Adenoma, Bile Duct; Adult; Aged; Aged, 80 and over; Angiotensin II; Antineoplastic Combined Chemothe | 1989 |
[Intra-arterial and intraportal therapy combined with decollateralization in unresectable cholangiocellular carcinoma--a case report].
Topics: Adenoma, Bile Duct; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, | 1989 |
[Combined hepatic arterial infusion chemotherapy with transcatheter arterial embolization and hyperthermia in primary liver cancer].
Topics: Adenoma, Bile Duct; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Carcinoma, | 1988 |
[A case of abdominal wall fistula due to cholangioma].
Topics: Abdominal Muscles; Adenoma, Bile Duct; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neo | 1985 |
Malignant hepatoma in the Bantu.
Topics: Adenoma, Bile Duct; Africa, Eastern; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotra | 1970 |
[Study in man of recirculation and tissue uptake of 5-FU 6 H3].
Topics: Adenoma, Bile Duct; Antimetabolites; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfu | 1971 |
[Clinical studies of primary hepatic carcinoma].
Topics: Adenoma, Bile Duct; Adolescent; Adult; Aged; Alkaline Phosphatase; Autopsy; Biopsy; Carcinoma, Hepat | 1971 |
Proceedings: Primary liver cancer. A review of the clinical features, blood groups, serum enzymes, therapy, and survival of 65 cases.
Topics: ABO Blood-Group System; Adenoma, Bile Duct; Adolescent; Adult; Aged; Alanine Transaminase; Alkaline | 1974 |