fluorouracil has been researched along with Cervix Diseases in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dungar, CF | 1 |
| Wilkinson, EJ | 1 |
| Holmes, MM | 1 |
| Weaver, SH | 1 |
| Vermillion, ST | 1 |
| Lakatosh, VP | 1 |
| Brodman, M | 1 |
| Dottino, P | 1 |
| Friedman, F | 1 |
| Heller, D | 1 |
| Bleiweiss, I | 1 |
| Sperling, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter Observational and Feasibility Study of Excision of Superficially Invasive Squamous Cell Carcinoma (SISCCA) of the Anal Canal and Perianus in HIV-Infected Persons[NCT02437851] | Phase 2 | 16 participants (Actual) | Interventional | 2015-04-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for fluorouracil and Cervix Diseases
| Article | Year |
|---|---|
A randomized, double-blind, placebo-controlled trial of 5-fluorouracil for the treatment of cervicovaginal human papillomavirus.
Topics: Administration, Intravaginal; Adolescent; Adult; Antimetabolites, Antineoplastic; Double-Blind Metho | 1999 |
[The treatment of benign processes of the cervix uteri associated with papillomavirus infection in women who have not given birth].
Topics: Adolescent; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Fluorouracil; Glycerol; Huma | 1999 |
2 other studies available for fluorouracil and Cervix Diseases
| Article | Year |
|---|---|
Vaginal columnar cell metaplasia. An acquired adenosis associated with topical 5-fluorouracil therapy.
Topics: Adult; Epithelial Cells; Epithelium; Female; Fluorouracil; Humans; Metaplasia; Middle Aged; Papillom | 1995 |
Human papillomavirus-associated lesions of the vagina and cervix. Treatment with a laser and topical 5-fluorouracil.
Topics: Administration, Topical; Biopsy; Clinical Protocols; Combined Modality Therapy; DNA; Female; Fluorou | 1992 |