Page last updated: 2024-10-27

fluorouracil and Cervix Diseases

fluorouracil has been researched along with Cervix Diseases in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dungar, CF1
Wilkinson, EJ1
Holmes, MM1
Weaver, SH1
Vermillion, ST1
Lakatosh, VP1
Brodman, M1
Dottino, P1
Friedman, F1
Heller, D1
Bleiweiss, I1
Sperling, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter Observational and Feasibility Study of Excision of Superficially Invasive Squamous Cell Carcinoma (SISCCA) of the Anal Canal and Perianus in HIV-Infected Persons[NCT02437851]Phase 216 participants (Actual)Interventional2015-04-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for fluorouracil and Cervix Diseases

ArticleYear
A randomized, double-blind, placebo-controlled trial of 5-fluorouracil for the treatment of cervicovaginal human papillomavirus.
    Infectious diseases in obstetrics and gynecology, 1999, Volume: 7, Issue:4

    Topics: Administration, Intravaginal; Adolescent; Adult; Antimetabolites, Antineoplastic; Double-Blind Metho

1999
[The treatment of benign processes of the cervix uteri associated with papillomavirus infection in women who have not given birth].
    Likars'ka sprava, 1999, Issue:6

    Topics: Adolescent; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Fluorouracil; Glycerol; Huma

1999

Other Studies

2 other studies available for fluorouracil and Cervix Diseases

ArticleYear
Vaginal columnar cell metaplasia. An acquired adenosis associated with topical 5-fluorouracil therapy.
    The Journal of reproductive medicine, 1995, Volume: 40, Issue:5

    Topics: Adult; Epithelial Cells; Epithelium; Female; Fluorouracil; Humans; Metaplasia; Middle Aged; Papillom

1995
Human papillomavirus-associated lesions of the vagina and cervix. Treatment with a laser and topical 5-fluorouracil.
    The Journal of reproductive medicine, 1992, Volume: 37, Issue:5

    Topics: Administration, Topical; Biopsy; Clinical Protocols; Combined Modality Therapy; DNA; Female; Fluorou

1992