fluorouracil has been researched along with Cerebral Primitive Neuroectodermal Tumor in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pancreatic neuroendocrine tumors (pNETs) are rare entities representing 1% to 3% of all malignant pancreatic neoplasms." | 5.72 | Long-term treatment with streptozocin/5-fluorouracil chemotherapy in patients with metastatic pancreatic neuroendocrine tumors: Case series. ( Keitel, V; Klose, S; Krause, A; Kreissl, MC; Müller, C; Venerito, M, 2022) |
| "Pancreatic neuroendocrine tumors (pNETs) are rare entities representing 1% to 3% of all malignant pancreatic neoplasms." | 1.72 | Long-term treatment with streptozocin/5-fluorouracil chemotherapy in patients with metastatic pancreatic neuroendocrine tumors: Case series. ( Keitel, V; Klose, S; Krause, A; Kreissl, MC; Müller, C; Venerito, M, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reher, D | 1 |
| Fehrenbach, U | 1 |
| Kayser, A | 1 |
| Pape, UF | 1 |
| Henes, FO | 1 |
| Cremer, B | 1 |
| Hörsch, D | 1 |
| Izbicki, J | 1 |
| Lohse, AW | 1 |
| Rinke, A | 1 |
| Schrader, J | 1 |
| Müller, C | 1 |
| Kreissl, MC | 1 |
| Klose, S | 1 |
| Krause, A | 1 |
| Keitel, V | 1 |
| Venerito, M | 1 |
2 other studies available for fluorouracil and Cerebral Primitive Neuroectodermal Tumor
| Article | Year |
|---|---|
Localization Defines Streptozotocin/5-FU Response in Primary Pancreatic Neuroendocrine Tumours.
Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Neoplasms, Second Primary; Neu | 2022 |
Long-term treatment with streptozocin/5-fluorouracil chemotherapy in patients with metastatic pancreatic neuroendocrine tumors: Case series.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Male; Middle Aged; Neopl | 2022 |