fluorouracil has been researched along with Cerebral Infarction in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
| Excerpt | Relevance | Reference |
|---|---|---|
| " CASE REPORT We report the case of a patient who was diagnosed with stage IV colorectal cancer and who underwent chemotherapy with a high dose of 5-FU as part of the FOLFIRI (Folinic Acid, Fluorouracil, Irinotecan) treatment plan." | 9.41 | Recurrent Reversible Stroke-Like Encephalopathy After 5-Fluorouracil (5-FU) Chemotherapy: A Case Report and Literature Review. ( Gofir, A; Hutajulu, SH; Nugroho, DB; Yuwono, KA, 2023) |
| " CASE REPORT We report the case of a patient who was diagnosed with stage IV colorectal cancer and who underwent chemotherapy with a high dose of 5-FU as part of the FOLFIRI (Folinic Acid, Fluorouracil, Irinotecan) treatment plan." | 5.41 | Recurrent Reversible Stroke-Like Encephalopathy After 5-Fluorouracil (5-FU) Chemotherapy: A Case Report and Literature Review. ( Gofir, A; Hutajulu, SH; Nugroho, DB; Yuwono, KA, 2023) |
| "In a transient 90-min middle cerebral artery occlusion (MCAO) model of rats, a large ischemic lesion is formed where macrophage-like cells massively accumulate, many of which express a macrophage marker, Iba1, and an oligodendrocyte progenitor cell marker, NG2 chondroitin sulfate proteoglycan (NG2); therefore, the cells were termed BINCs (Brain Iba1(+)/NG2(+) Cells)." | 1.36 | Iba1(+)/NG2(+) macrophage-like cells expressing a variety of neuroprotective factors ameliorate ischemic damage of the brain. ( Inoue, A; Kumon, Y; Matsumoto, H; Ohnishi, T; Ohue, S; Smirkin, A; Tagawa, M; Takahashi, H; Tanaka, J; Watanabe, H; Yano, H, 2010) |
| "Suspected pulmonary embolism was demonstrated by CT scan." | 1.31 | [Complicated antiphospholid antibody syndrome]. ( Eifrig, B; Hegewisch-Becker, S; Hossfeld, DK; Langer, F; Marx, G; Neuber, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Yuwono, KA | 1 |
| Hutajulu, SH | 1 |
| Gofir, A | 1 |
| Nugroho, DB | 1 |
| Kurniadi, I | 1 |
| Yamada, D | 1 |
| Wirya, AY | 1 |
| Norimatsu, Y | 1 |
| Kuzumi, A | 1 |
| Ogaki, J | 1 |
| Takahashi, N | 1 |
| Sato, S | 1 |
| Smirkin, A | 1 |
| Matsumoto, H | 1 |
| Takahashi, H | 1 |
| Inoue, A | 1 |
| Tagawa, M | 1 |
| Ohue, S | 1 |
| Watanabe, H | 1 |
| Yano, H | 1 |
| Kumon, Y | 1 |
| Ohnishi, T | 1 |
| Tanaka, J | 1 |
| Katoh, K | 1 |
| Sone, M | 1 |
| Kuroda, T | 1 |
| Nakasato, T | 1 |
| Ehara, S | 1 |
| Satoh, C | 1 |
| Ohtsuka, K | 1 |
| Higuchi, T | 1 |
| El Amrani, M | 1 |
| Heinzlef, O | 1 |
| Debroucker, T | 1 |
| Roullet, E | 1 |
| Bousser, MG | 1 |
| Amarenco, P | 1 |
| Langer, F | 1 |
| Eifrig, B | 1 |
| Hegewisch-Becker, S | 1 |
| Marx, G | 1 |
| Neuber, K | 1 |
| Hossfeld, DK | 1 |
1 review available for fluorouracil and Cerebral Infarction
| Article | Year |
|---|---|
Recurrent Reversible Stroke-Like Encephalopathy After 5-Fluorouracil (5-FU) Chemotherapy: A Case Report and Literature Review.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cerebral Infarction; Colorectal Neoplasms; Fluoroura | 2023 |
5 other studies available for fluorouracil and Cerebral Infarction
| Article | Year |
|---|---|
Trousseau syndrome associated with cutaneous squamous cell carcinoma.
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Atherosclerosis; Carcinoma, Squamous Cell; Carot | 2018 |
Iba1(+)/NG2(+) macrophage-like cells expressing a variety of neuroprotective factors ameliorate ischemic damage of the brain.
Topics: Animals; Antigens; Bone Marrow Transplantation; Brain; Brain Ischemia; Bromodeoxyuridine; Calcium-Bi | 2010 |
[A case of cerebral infarction caused by disseminated intravascular coagulation during hepatic arterial infusion chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cerebral Infarction; Colorectal Neoplasms; Dis | 2005 |
Brain infarction following 5-fluorouracil and cisplatin therapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cerebral Infarction; Cisplatin; Fatal Outcome; | 1998 |
[Complicated antiphospholid antibody syndrome].
Topics: Antineoplastic Combined Chemotherapy Protocols; Antiphospholipid Syndrome; Breast Neoplasms; Carcino | 2002 |