fluorouracil and Cerebral Cryptococcosis studies

fluorouracil and Cerebral Cryptococcosis

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

Excerpt	Relevance	Reference
"We provided pharmaceutical care for a cryptococcal meningitis case to study the role that clinical pharmacists played in clinical pharmacotherapy."	1.35	[Pharmaceutical care of patient with cryptococcal meningitis: a case report]. ( Li, CX; Liu, F; Zhai, SD; Zhang, XY, 2009)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (66.67)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

2 (66.67)

29.6817

2010's

1 (33.33)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Judd, WR	1
Shely, RN	1
Ratliff, PD	1
Reymann, MT	1
Li, CX	1
Liu, F	1
Zhang, XY	1
Zhai, SD	1
Vermes, A	1
Guchelaar, HJ	1
van Kuilenburg, AB	1
Dankert, J	1

Studies

Judd, WR

Shely, RN

Ratliff, PD

Reymann, MT

Li, CX

Liu, F

Zhang, XY

Zhai, SD

Vermes, A

Guchelaar, HJ

van Kuilenburg, AB

Dankert, J

Trials

1 trial available for fluorouracil and Cerebral Cryptococcosis

Article	Year
5-fluorocytosine-related bone-marrow depression and conversion to fluorouracil: a pilot study. Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:1 Topics: Adult; Aged; beta-Alanine; Biotransformation; Bone Marrow; Candidiasis; Female; Flucytosine; Fluorou	2002

Article

Year

5-fluorocytosine-related bone-marrow depression and conversion to fluorouracil: a pilot study.

Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:1

Topics: Adult; Aged; beta-Alanine; Biotransformation; Bone Marrow; Candidiasis; Female; Flucytosine; Fluorou

2002

Other Studies

2 other studies available for fluorouracil and Cerebral Cryptococcosis

Article	Year
False-negative cerebrospinal fluid fungal culture results following oral antineoplastic therapy with a 5-fluorouracil derivative. Journal of clinical pharmacy and therapeutics, 2015, Volume: 40, Issue:6 Topics: Administration, Oral; Aged; Antineoplastic Agents; Capecitabine; Cerebrospinal Fluid; Cryptococcosis	2015
[Pharmaceutical care of patient with cryptococcal meningitis: a case report]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2009, Oct-18, Volume: 41, Issue:5 Topics: Adult; Amphotericin B; Antifungal Agents; Drug Monitoring; Drug Therapy, Combination; Fluorouracil;	2009

Article

Year

False-negative cerebrospinal fluid fungal culture results following oral antineoplastic therapy with a 5-fluorouracil derivative.

Journal of clinical pharmacy and therapeutics, 2015, Volume: 40, Issue:6

Topics: Administration, Oral; Aged; Antineoplastic Agents; Capecitabine; Cerebrospinal Fluid; Cryptococcosis

2015

[Pharmaceutical care of patient with cryptococcal meningitis: a case report].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2009, Oct-18, Volume: 41, Issue:5

Topics: Adult; Amphotericin B; Antifungal Agents; Drug Monitoring; Drug Therapy, Combination; Fluorouracil;

2009