fluorouracil has been researched along with Cell Transformation, Viral in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Cell Transformation, Viral: An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Head and neck squamous cell carcinoma (HNSCC) is the most common malignant epithelial tumor in the upper aerodigestive tract." | 1.39 | Chemotherapeutic alteration of VEGF, PDGF and PDGFRα/β expression under 5-FU vs. docetaxel in HPV-transformed squamous cell carcinoma compared to HPV-negative HNSCC in vitro. ( Aderhold, C; Birk, R; Erben, P; Faber, A; Hofheinz, RD; Hörmann, K; Sauter, A; Schultz, JD; Sommer, JU; Stern-Straeter, J; Umbreit, C, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, J | 1 |
| Fan, H | 1 |
| Ma, Y | 1 |
| Liang, D | 1 |
| Huang, R | 1 |
| Wang, J | 1 |
| Zhou, F | 1 |
| Kan, Q | 1 |
| Ming, L | 1 |
| Li, H | 1 |
| Giercksky, KE | 1 |
| Nesland, JM | 1 |
| Suo, Z | 1 |
| Aderhold, C | 1 |
| Umbreit, C | 1 |
| Faber, A | 1 |
| Sauter, A | 1 |
| Sommer, JU | 1 |
| Birk, R | 1 |
| Erben, P | 1 |
| Hofheinz, RD | 1 |
| Stern-Straeter, J | 1 |
| Hörmann, K | 1 |
| Schultz, JD | 1 |
| Lindel, K | 1 |
| Helmke, B | 1 |
| Simon, C | 1 |
| Weber, KJ | 1 |
| Debus, J | 1 |
| de Villiers, EM | 1 |
| Chłopkiewicz, B | 1 |
| Koziorowska, JH | 1 |
| Ruscetti, S | 1 |
| Aurigemma, R | 1 |
| Yuan, CC | 1 |
| Sawyer, S | 1 |
| Blair, DG | 1 |
| Lasneret, J | 1 |
| Dianoux, L | 1 |
| Lesser, J | 1 |
| Peries, J | 1 |
| Canivet, M | 1 |
6 other studies available for fluorouracil and Cell Transformation, Viral
| Article | Year |
|---|---|
Notch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomas.
Topics: Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Transformation, Vi | 2013 |
Chemotherapeutic alteration of VEGF, PDGF and PDGFRα/β expression under 5-FU vs. docetaxel in HPV-transformed squamous cell carcinoma compared to HPV-negative HNSCC in vitro.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Blotting, West | 2013 |
Cutaneous human papillomavirus in head and neck squamous cell carcinomas.
Topics: Aged; Alcohol Drinking; Alphapapillomavirus; Antineoplastic Combined Chemotherapy Protocols; Carbopl | 2009 |
Transforming activities of methotrexate, hydroxyurea and 5-fluorouracil in different cell systems.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Do | 1983 |
Induction of erythropoietin responsiveness in murine hematopoietic cells by the gag-myb-ets-containing ME26 virus.
Topics: Animals; Cell Line; Cell Transformation, Viral; Defective Viruses; Erythropoiesis; Erythropoietin; F | 1992 |
In vitro induction of early mouse embryo intracisternal particles (epsilon particles) in cultured cell lines.
Topics: Animals; Azacitidine; Cell Line; Cell Line, Transformed; Cell Transformation, Viral; Cycloheximide; | 1990 |