fluorouracil has been researched along with Cataract, Membranous in 49 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether the use of postoperative subconjunctival 5-fluorouracil (5-FU) reduces the risk of trabeculectomy bleb failure after uncomplicated small incisional cataract surgery." | 7.76 | Use of 5-Fluorouracil injections to reduce the risk of trabeculectomy bleb failure after cataract surgery. ( Salmon, JF; Shahid, H, 2010) |
| "This study was designed to evaluate the long-term effect of phacoemulsification, lens implantation combined with trabeculectomy augmented with 5-Fluorouracil (phaco-trab-5-Fu) in Asian glaucoma patients with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG)." | 7.73 | [The long-term effect of phacoemulsification combined with trabeculectomy and intraoperative 5-fluorouracil in glaucoma patients]. ( Cai, Y; Li, MY; Lim, BA; Lim, Z; Oen, F; Seah, S; Yan, XM, 2005) |
| "To observe the effect of the means of subconjunctiva injection with 5-Fluorouracil (5-Fu) and Triamcinolone to treat the membrane on the anterior surface of intraocular lens after traumatic cataract surgery." | 7.73 | [Combined 5-Fu and triamcinolone to treat the membrane on the anterior surface of intraocular lens after the surgery of traumatic cataract]. ( Chen, L; Xu, D; Ye, K, 2005) |
| "To report a transient cataract after bleb needling and subconjunctival injection of 5-fluorouracil." | 7.72 | Transient, profound cataract associated with intracameral 5-fluorouracil. ( Libre, PE, 2003) |
| "Patients with both cataract and glaucoma underwent combined mitomycin C trabeculectomy, extracapsular cataract extraction, and intraocular lens implantation." | 7.69 | One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction. ( Bueche, MJ; Feuer, WJ; Grajewski, AL; Joos, KM; Palmberg, PF, 1995) |
| "Thapsigargin was ineffective in this animal model." | 5.35 | Irrigation with thapsigargin and various concentrations of 5-fluorouracil in a sealed-capsule irrigation device in young rabbit eyes to prevent after-cataract. ( Abdelwahab, MT; Kugelberg, M; Zetterström, C, 2008) |
| "After-cataract was evaluated in 3 ways: clinically, from photographs, and histologically." | 5.33 | After-cataract evaluation after using balanced salt solution, distilled deionized water, and 5-fluorouracil with a sealed-capsule irrigation device in the eyes of 4-week-old rabbits. ( Abdelwahab, MT; Kugelberg, M; Kugelberg, U; Zetterström, C, 2006) |
| "We examined the safety and efficacy of 5-fluorouracil in eyes with open-angle glaucoma undergoing combined cataract removal and filtration surgery." | 5.07 | 5-Fluorouracil after primary combined filtration surgery. ( Gieser, DK; Goldenfeld, M; Krupin, T; Liebmann, JM; Ritch, R; Rosenberg, LF; Ruderman, JM; Shields, MB; Wong, PC, 1994) |
| "The preponderance of evidence from the literature suggests a small (2-4 mmHg) benefit from the use of mitomycin-C (MMC), but not 5-fluorouracil (5-FU), in combined cataract and glaucoma surgery (evidence grade B)." | 4.81 | Effect of technique on intraocular pressure after combined cataract and glaucoma surgery: An evidence-based review. ( Bass, EB; Congdon, N; Friedman, DS; Jampel, HD; Kempen, JH; Levkovitch-Verbin, H; Lubomski, LH; Quigley, H; Robinson, KA, 2002) |
| "To determine whether the use of postoperative subconjunctival 5-fluorouracil (5-FU) reduces the risk of trabeculectomy bleb failure after uncomplicated small incisional cataract surgery." | 3.76 | Use of 5-Fluorouracil injections to reduce the risk of trabeculectomy bleb failure after cataract surgery. ( Salmon, JF; Shahid, H, 2010) |
| "This study was designed to evaluate the long-term effect of phacoemulsification, lens implantation combined with trabeculectomy augmented with 5-Fluorouracil (phaco-trab-5-Fu) in Asian glaucoma patients with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG)." | 3.73 | [The long-term effect of phacoemulsification combined with trabeculectomy and intraoperative 5-fluorouracil in glaucoma patients]. ( Cai, Y; Li, MY; Lim, BA; Lim, Z; Oen, F; Seah, S; Yan, XM, 2005) |
| "To observe the effect of the means of subconjunctiva injection with 5-Fluorouracil (5-Fu) and Triamcinolone to treat the membrane on the anterior surface of intraocular lens after traumatic cataract surgery." | 3.73 | [Combined 5-Fu and triamcinolone to treat the membrane on the anterior surface of intraocular lens after the surgery of traumatic cataract]. ( Chen, L; Xu, D; Ye, K, 2005) |
| "To report a transient cataract after bleb needling and subconjunctival injection of 5-fluorouracil." | 3.72 | Transient, profound cataract associated with intracameral 5-fluorouracil. ( Libre, PE, 2003) |
| "To determine and compare the intraocular pressure (IOP) lowering effects of single-incision combined phacoemulsification and trabeculectomy with phacoemulsification done after previous trabeculectomy, both with an intraoperative dose of 5-fluorouracil (5-FU)." | 3.70 | Combined versus sequential phacotrabeculectomy with intraoperative 5-fluorouracil. ( Donoso, R; Rodríguez, A, 2000) |
| "To study the association between after-cataract and secondary glaucoma after lensectomy and 5-fluorouracil treatment in an experimental infant rabbit model." | 3.70 | After-cataract and secondary glaucoma in the aphakic infant rabbit. ( Holmén, JB; Kugelberg, U; Lundgren, B; Lundvall, A; Zetterström, C, 2000) |
| "A concurrent series (from January 1, 1987, to October 1, 1997) of one surgeon's consecutive 585 (456 patients) combined cataract extraction, intraocular lens implantation, and trabeculectomy surgeries, some with intraoperative mitomycin C and/or postoperative subconjunctival 5-fluorouracil." | 3.70 | Outcomes of combined cataract extraction, lens implantation, and trabeculectomy surgeries. ( Hahn, J; Larive, B; Rockwood, EJ, 2000) |
| "To determine whether there is increased risk to the corneal endothelium when mitomycin C is used in trabeculectomy surgery instead of fluorouracil, and whether these agents play a role in accelerating cataract formation." | 3.69 | Effect of mitomycin C and fluorouracil-supplemented trabeculectomies on the anterior segment. ( Chaturvedi, N; Dreyer, EB; Zurakowski, D, 1995) |
| "Patients with both cataract and glaucoma underwent combined mitomycin C trabeculectomy, extracapsular cataract extraction, and intraocular lens implantation." | 3.69 | One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction. ( Bueche, MJ; Feuer, WJ; Grajewski, AL; Joos, KM; Palmberg, PF, 1995) |
| "To prevent the development of secondary cataract, mitomycin C (MC, 0." | 3.69 | Prevention of secondary cataract by antimitotic drugs: experimental study. ( Alió, JL; Ismail, MM; Ruiz Moreno, JM, 1996) |
| "To study the ability of homoharringtonine, 5-fluorouracil and adriamycin on inhibiting the proliferation of rabbit lens epithelial cells (RLEC) and the prevention of after cataract by using homoharringtonine." | 3.69 | [Inhibition of rabbit lens epithelial cell proliferation]. ( Li, S; Su, X; Zheng, J, 1996) |
| "4), use of antiglaucoma medication, dosage of topical steroid postoperatively, and being operated on by a trainee surgeon (odds ratio, 2." | 2.72 | Effect of trabeculectomy on lens opacities in an East Asian population. ( Aung, T; Chew, PT; Devereux, JG; Foster, PJ; Gazzard, G; Husain, R; Khaw, PT; Oen, FT; Seah, SK, 2006) |
| "Thapsigargin was ineffective in this animal model." | 1.35 | Irrigation with thapsigargin and various concentrations of 5-fluorouracil in a sealed-capsule irrigation device in young rabbit eyes to prevent after-cataract. ( Abdelwahab, MT; Kugelberg, M; Zetterström, C, 2008) |
| "Irrigation with 5-FU 50 mg/mL in the sealed-capsule irrigation device was safe and caused no apparent damage to the adjacent intraocular tissues." | 1.34 | Safety of irrigation with 5-fluorouracil in a sealed-capsule irrigation device in the rabbit eye. ( Abdelwahab, MT; Kugelberg, M; Seregard, S; Zetterström, C, 2007) |
| "After-cataract was evaluated in 3 ways: clinically, from photographs, and histologically." | 1.33 | After-cataract evaluation after using balanced salt solution, distilled deionized water, and 5-fluorouracil with a sealed-capsule irrigation device in the eyes of 4-week-old rabbits. ( Abdelwahab, MT; Kugelberg, M; Kugelberg, U; Zetterström, C, 2006) |
| "5-Fluorouracil was safe and improved trabeculectomy survival." | 1.31 | The efficacy and safety of intraoperative and/or postoperative 5-fluorouracil in trabeculectomy and phacotrabeculectomy. ( Goldberg, I; Mohsin, M; Singh, RP, 2001) |
| "Intraocular pressures were lower in the group that received MMC compared to the 5-FU group, but not in the group that did not receive antimetabolites, at all time intervals measured (P < ." | 1.30 | Comparison of phacotrabeculectomy with 5-fluorouracil, mitomycin-C, and without antifibrotic agents. ( Budenz, DL; Gordon, J; Keates, EU; Piltz-Seymour, J; Pyfer, M; Singh, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.12) | 18.7374 |
| 1990's | 16 (32.65) | 18.2507 |
| 2000's | 26 (53.06) | 29.6817 |
| 2010's | 4 (8.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vinod, K | 1 |
| Gedde, SJ | 1 |
| Feuer, WJ | 2 |
| Panarelli, JF | 1 |
| Chang, TC | 1 |
| Chen, PP | 1 |
| Parrish, RK | 1 |
| Na, JH | 1 |
| Sung, KR | 1 |
| Shin, JA | 1 |
| Moon, JI | 1 |
| Abdelwahab, MT | 4 |
| Lindell, I | 1 |
| Hultenby, K | 1 |
| Kugelberg, M | 4 |
| Milverton, EJ | 1 |
| Liu, YY | 1 |
| Huang, X | 1 |
| Wei, RL | 1 |
| Li, Y | 1 |
| Cheng, JW | 1 |
| Shahid, H | 1 |
| Salmon, JF | 1 |
| Spalton, DJ | 1 |
| Jampel, HD | 1 |
| Friedman, DS | 1 |
| Lubomski, LH | 1 |
| Kempen, JH | 1 |
| Quigley, H | 1 |
| Congdon, N | 1 |
| Levkovitch-Verbin, H | 1 |
| Robinson, KA | 1 |
| Bass, EB | 1 |
| Libre, PE | 1 |
| Cochener, B | 3 |
| Bougaran, R | 3 |
| Pandey, S | 2 |
| Apple, D | 2 |
| Colin, J | 3 |
| O'Brart, DP | 1 |
| Shiew, M | 1 |
| Edmunds, B | 1 |
| Fernandez, V | 1 |
| Fragoso, MA | 1 |
| Billotte, C | 1 |
| Lamar, P | 1 |
| Orozco, MA | 1 |
| Dubovy, S | 1 |
| Willcox, M | 1 |
| Parel, JM | 2 |
| Cai, Y | 1 |
| Lim, Z | 1 |
| Lim, BA | 1 |
| Oen, F | 1 |
| Yan, XM | 1 |
| Li, MY | 1 |
| Seah, S | 1 |
| Shingleton, BJ | 1 |
| Price, RS | 1 |
| O'Donoghue, MW | 1 |
| Goyal, S | 1 |
| Husain, R | 1 |
| Aung, T | 1 |
| Gazzard, G | 1 |
| Foster, PJ | 1 |
| Devereux, JG | 1 |
| Chew, PT | 1 |
| Oen, FT | 1 |
| Khaw, PT | 2 |
| Seah, SK | 1 |
| Li, G | 1 |
| Kasner, O | 1 |
| Kugelberg, U | 2 |
| Zetterström, C | 4 |
| Chang, L | 1 |
| Thiagarajan, M | 1 |
| Moseley, M | 1 |
| Woodruff, S | 1 |
| Bentley, C | 1 |
| Bloom, P | 1 |
| Ye, K | 1 |
| Xu, D | 1 |
| Chen, L | 1 |
| Chakraborty, D | 1 |
| Dutta Choudhury, B | 1 |
| Duncan, G | 1 |
| Wang, L | 1 |
| Neilson, GJ | 1 |
| Wormstone, IM | 1 |
| Seregard, S | 1 |
| Slezak, H | 1 |
| Guo, H | 1 |
| Li, S | 2 |
| Cao, X | 1 |
| Dreyer, EB | 1 |
| Chaturvedi, N | 1 |
| Zurakowski, D | 1 |
| Joos, KM | 1 |
| Bueche, MJ | 1 |
| Palmberg, PF | 1 |
| Grajewski, AL | 1 |
| Wong, PC | 1 |
| Ruderman, JM | 1 |
| Krupin, T | 1 |
| Goldenfeld, M | 1 |
| Rosenberg, LF | 1 |
| Shields, MB | 1 |
| Ritch, R | 1 |
| Liebmann, JM | 1 |
| Gieser, DK | 1 |
| Ismail, MM | 1 |
| Alió, JL | 2 |
| Ruiz Moreno, JM | 1 |
| Caprioli, J | 1 |
| Park, HJ | 1 |
| Weitzman, M | 1 |
| Gandolfi, SA | 1 |
| Vecchi, M | 1 |
| Yamagami, S | 1 |
| Hamada, N | 1 |
| Araie, M | 1 |
| Shirato, S | 1 |
| Su, X | 1 |
| Zheng, J | 1 |
| Duchesne, B | 1 |
| Tahi, H | 1 |
| Gautier, S | 1 |
| Jallet, V | 1 |
| Villain, F | 1 |
| Gillies, MC | 1 |
| Brooks, AM | 1 |
| Young, S | 1 |
| Gillies, B | 1 |
| Simpson, JM | 1 |
| Goldberg, I | 2 |
| Samuelson, TW | 1 |
| Blumenthal, M | 1 |
| Glovinsky, Y | 1 |
| Budenz, DL | 1 |
| Pyfer, M | 1 |
| Singh, K | 1 |
| Gordon, J | 1 |
| Piltz-Seymour, J | 1 |
| Keates, EU | 1 |
| Gayton, JL | 1 |
| Van Der Karr, M | 1 |
| Sanders, V | 1 |
| Donoso, R | 1 |
| Rodríguez, A | 1 |
| Lundvall, A | 1 |
| Lundgren, B | 1 |
| Holmén, JB | 1 |
| Rockwood, EJ | 1 |
| Larive, B | 1 |
| Hahn, J | 1 |
| Lichter, PR | 1 |
| Musch, DC | 1 |
| Gillespie, BW | 1 |
| Guire, KE | 1 |
| Janz, NK | 1 |
| Wren, PA | 1 |
| Mills, RP | 1 |
| Singh, RP | 1 |
| Mohsin, M | 1 |
| Pandey, SK | 1 |
| Apple, DJ | 1 |
| Werner, L | 1 |
| Trivedi, RH | 1 |
| Macky, TA | 1 |
| Izak, AM | 1 |
| Chan, RC | 1 |
| Shukovsky, LJ | 1 |
| Ruíz, JM | 1 |
| Medrano, M | 1 |
| Blankenship, GW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy[NCT00695747] | 95 participants (Actual) | Interventional | 1998-01-31 | Completed | |||
| [NCT00000149] | Phase 3 | 0 participants | Interventional | 1993-10-31 | Active, not recruiting | ||
| Phacoemulsification Combined With Trabeculectomy Versus Phacoemulsification Combined With Trabeculotomy for Treatment of Chronic Angle Closure Glaucoma[NCT04683055] | 50 participants (Actual) | Interventional | 2020-10-28 | Completed | |||
| Glaucoma Eye Drop Instillation: Impact of Education[NCT01416415] | 119 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Not practical to continue due interim results) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for fluorouracil and Cataract, Membranous
| Article | Year |
|---|---|
Effect of technique on intraocular pressure after combined cataract and glaucoma surgery: An evidence-based review.
Topics: Antimetabolites, Antineoplastic; Cataract; Cataract Extraction; Evidence-Based Medicine; Fluorouraci | 2002 |
Management of coincident glaucoma and cataract.
Topics: Cataract; Cataract Extraction; Exfoliation Syndrome; Fluorouracil; Glaucoma; Humans; Lenses, Intraoc | 1995 |
Surgical consequences in coexisting cataract and glaucoma.
Topics: Cataract; Cataract Extraction; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Lenses, Intraoc | 1995 |
10 trials available for fluorouracil and Cataract, Membranous
| Article | Year |
|---|---|
A randomised, prospective study comparing trabeculectomy with viscocanalostomy with adjunctive antimetabolite usage for the management of open angle glaucoma uncontrolled by medical therapy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Blister; Cataract; Female; Filtering Surgery; Fluor | 2004 |
Comparison of 1-site versus 2-site phacotrabeculectomy.
Topics: Antihypertensive Agents; Case-Control Studies; Cataract; Fluorouracil; Follow-Up Studies; Glaucoma; | 2006 |
Effect of trabeculectomy on lens opacities in an East Asian population.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Cataract; Combined Modality Therapy; Disease Progre | 2006 |
5-Fluorouracil after primary combined filtration surgery.
Topics: Aged; Cataract; Cataract Extraction; Combined Modality Therapy; Female; Fluorouracil; Glaucoma, Open | 1994 |
Temporal corneal phacoemulsification combined with superior trabeculectomy: a controlled study.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cataract; Cornea; Female; Fluorouracil; Glaucoma; Hum | 1996 |
5-fluorouracil in combined trabeculectomy and clear-cornea phacoemulsification with posterior chamber intraocular lens implantation. A one-year randomized, controlled clinical trial.
Topics: Antimetabolites; Cataract; Cornea; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; In | 1997 |
A randomized phase II trial of interferon-alpha2b versus 5-fluorouracil after trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Cataract; Cataract Extraction; Connective Tissue; Double-Blind Metho | 1999 |
Combined cataract and glaucoma surgery: trabeculectomy versus endoscopic laser cycloablation.
Topics: Cataract; Ciliary Body; Endoscopy; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intrao | 1999 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Evaluation of a single intravitreal injection of 5-fluorouracil in vitrectomy cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Cataract; Clinical Trials as Topic; Co | 1989 |
36 other studies available for fluorouracil and Cataract, Membranous
| Article | Year |
|---|---|
Practice Preferences for Glaucoma Surgery: A Survey of the American Glaucoma Society.
Topics: Alkylating Agents; Cataract; Female; Filtering Surgery; Fluorouracil; Glaucoma Drainage Implants; Gl | 2017 |
Antifibrotic effects of pirfenidone on Tenon's fibroblasts in glaucomatous eyes: comparison with mitomycin C and 5-fluorouracil.
Topics: Actins; Adult; Alkylating Agents; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Catara | 2015 |
Transmission electron microscopy of the rabbit posterior capsule irrigated with thapsigargin and 5-fluorouracil in a sealed-capsule irrigation device.
Topics: Animals; Antimetabolites; Cataract; Enzyme Inhibitors; Fluorouracil; Lens Capsule, Crystalline; Lens | 2009 |
Irrigation of the capsular bag using a sealed-capsule irrigation device and 5-fluorouracil.
Topics: Antimetabolites; Cataract; Cataract Extraction; Female; Fluorouracil; Humans; Lens Capsule, Crystall | 2009 |
[Empirical study on nano-fluorouracil-coated intraocular lens inhibiting posterior capsule opacification].
Topics: Animals; Cataract; Fluorouracil; Lens Implantation, Intraocular; Lenses, Intraocular; Nanostructures | 2009 |
Use of 5-Fluorouracil injections to reduce the risk of trabeculectomy bleb failure after cataract surgery.
Topics: Aged; Aged, 80 and over; Cataract; Cataract Extraction; Conjunctiva; Drug Administration Schedule; F | 2010 |
Re: The report 'irrigation of the capsular bag using a sealed-capsule irrigation device and 5-fluorouracil' by Milverton.
Topics: Antimetabolites; Cataract; Fluorouracil; Humans; Lens Capsule, Crystalline; Phacoemulsification | 2010 |
Transient, profound cataract associated with intracameral 5-fluorouracil.
Topics: Antimetabolites, Antineoplastic; Cataract; Filtering Surgery; Fluorouracil; Glaucoma, Open-Angle; Hu | 2003 |
[Non-biodegradable drug-sustained capsular ring for prevention of secondary cataract. Part I: In vitro evaluation].
Topics: Biocompatible Materials; Biodegradation, Environmental; Cataract; Cataract Extraction; Delayed-Actio | 2003 |
[Nonbiodegradable drug-sustained capsular ring for prevention of secondary cataract. Part II: In vivo evaluation].
Topics: Animals; Antimetabolites; Biocompatible Materials; Capsules; Cataract; Delayed-Action Preparations; | 2003 |
Efficacy of various drugs in the prevention of posterior capsule opacification: experimental study of rabbit eyes.
Topics: Acetates; Acetic Acid; Animals; Capsulorhexis; Cataract; Cell Proliferation; Drug Combinations; Edet | 2004 |
[The long-term effect of phacoemulsification combined with trabeculectomy and intraoperative 5-fluorouracil in glaucoma patients].
Topics: Adult; Aged; Aged, 80 and over; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; | 2005 |
Review of consecutive phacotrabeculectomies supplemented with early needle revision and antimetabolites.
Topics: Aged; Aged, 80 and over; Antimetabolites; Cataract; Female; Fluorouracil; Glaucoma; Humans; Intraocu | 2006 |
After-cataract evaluation after using balanced salt solution, distilled deionized water, and 5-fluorouracil with a sealed-capsule irrigation device in the eyes of 4-week-old rabbits.
Topics: Acetates; Animals; Animals, Newborn; Cataract; Cell Proliferation; Drug Combinations; Epithelial Cel | 2006 |
Intraocular pressure outcome in primary 5FU phacotrabeculectomies compared with 5FU trabeculectomies.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cataract; Combined Modality Therapy | 2006 |
[Combined 5-Fu and triamcinolone to treat the membrane on the anterior surface of intraocular lens after the surgery of traumatic cataract].
Topics: Administration, Topical; Cataract; Cataract Extraction; Conjunctiva; Drug Therapy, Combination; Eye | 2005 |
Phacotrabeculectomy study.
Topics: Alkylating Agents; Antihypertensive Agents; Cataract; Fluorouracil; Glaucoma; Humans; Intraocular Pr | 2007 |
Lens cell survival after exposure to stress in the closed capsular bag.
Topics: Actins; Animals; Cataract; Cell Culture Techniques; Cell Survival; Fluorescent Antibody Technique, I | 2007 |
Safety of irrigation with 5-fluorouracil in a sealed-capsule irrigation device in the rabbit eye.
Topics: Animals; Antimetabolites; Cataract; Cell Count; Endothelium, Corneal; Fluorouracil; Lens Capsule, Cr | 2007 |
Irrigation with thapsigargin and various concentrations of 5-fluorouracil in a sealed-capsule irrigation device in young rabbit eyes to prevent after-cataract.
Topics: Animals; Antimetabolites; Cataract; Enzyme Inhibitors; Fluorouracil; Lens, Crystalline; Postoperativ | 2008 |
[Drug-induced eye lesions in the aged].
Topics: Aged; Antipsychotic Agents; Aspirin; Cataract; Conjunctival Diseases; Corneal Diseases; Eye Diseases | 1983 |
[Human lens epithelial cell culture and its proliferative inhibition in vitro].
Topics: Adolescent; Adult; Age Factors; Cataract; Cell Division; Cells, Cultured; Child; Child, Preschool; E | 1995 |
Effect of mitomycin C and fluorouracil-supplemented trabeculectomies on the anterior segment.
Topics: Aged; Anterior Eye Segment; Cataract; Cell Count; Chemotherapy, Adjuvant; Female; Fluorouracil; Glau | 1995 |
One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction.
Topics: Adult; Aged; Astigmatism; Cataract; Cataract Extraction; Female; Fluorouracil; Follow-Up Studies; Gl | 1995 |
Prevention of secondary cataract by antimitotic drugs: experimental study.
Topics: Animals; Antineoplastic Agents; Cataract; Cataract Extraction; Cell Count; Fluorouracil; Lens Capsul | 1996 |
Risk factors for unsatisfactory intraocular pressure control in combined trabeculectomy and cataract surgery.
Topics: Aged; Aged, 80 and over; Antimetabolites; Cataract; Cataract Extraction; Female; Fluorouracil; Follo | 1997 |
[Inhibition of rabbit lens epithelial cell proliferation].
Topics: Animals; Cataract; Cell Division; Cells, Cultured; Doxorubicin; Epithelial Cells; Fluorouracil; Grow | 1996 |
[Implantation of controlled-release 5-FU for the prevention of secondary cataract: preliminary study].
Topics: Animals; Antimetabolites; Cataract; Cataract Extraction; Delayed-Action Preparations; Fluorouracil; | 1998 |
Comparison of phacotrabeculectomy with 5-fluorouracil, mitomycin-C, and without antifibrotic agents.
Topics: Aged; Cataract; Chemotherapy, Adjuvant; Fibrosis; Fluorouracil; Glaucoma; Humans; Intraocular Pressu | 1999 |
Combined versus sequential phacotrabeculectomy with intraoperative 5-fluorouracil.
Topics: Aged; Antimetabolites; Cataract; Conjunctiva; Fluorouracil; Glaucoma, Open-Angle; Humans; Injections | 2000 |
After-cataract and secondary glaucoma in the aphakic infant rabbit.
Topics: Animals; Animals, Newborn; Anterior Chamber; Aphakia, Postcataract; Cataract; Fluorouracil; Glaucoma | 2000 |
Outcomes of combined cataract extraction, lens implantation, and trabeculectomy surgeries.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Cataract; Cataract Extraction; Female; | 2000 |
The efficacy and safety of intraoperative and/or postoperative 5-fluorouracil in trabeculectomy and phacotrabeculectomy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Cataract; Female; Fluorouracil; Glaucom | 2001 |
Intracapsular ring sustained 5-fluorouracil delivery system for the prevention of posterior capsule opacification in rabbits: a histological study.
Topics: Animals; Antimetabolites; Cataract; Cornea; Drug Delivery Systems; Drug Implants; Epithelial Cells; | 2002 |
Effects of irradiation on the eye.
Topics: Blindness; Cataract; Eye; Eye Diseases; Fluorouracil; Humans; Nose Neoplasms; Paranasal Sinus Neopla | 1976 |
Inhibition of posterior capsule opacification by 5-fluorouracil in rabbits.
Topics: Animals; Cataract; Cataract Extraction; Cell Count; Cell Division; Endothelium, Corneal; Epithelium; | 1990 |