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fluorouracil and Cardiac Rupture, Traumatic

fluorouracil has been researched along with Cardiac Rupture, Traumatic in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Glycine has been shown to protect livers from CTx-induced injury and oxidative stress, and it reduces platelet aggregation and improves microperfusion."5.56Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats. ( Bausys, A; Feldbacher, N; Hoefler, G; Kolb-Lenz, D; Leber, B; Maneikyte, J; Schemmer, P; Stiegler, P; Strupas, K, 2020)
"The case history is reported of a 51-year-old man with metastatic colonic carcinoma who was receiving a continuous 5-fluorouracil infusion via a central venous catheter and who developed cardiac perforation and pericardial effusion."3.69Cardiac perforation associated with continuous infusional chemotherapy. ( Cooper, RA; James, RD; Taylor, KJ, 1996)
"Glycine has been shown to protect livers from CTx-induced injury and oxidative stress, and it reduces platelet aggregation and improves microperfusion."1.56Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats. ( Bausys, A; Feldbacher, N; Hoefler, G; Kolb-Lenz, D; Leber, B; Maneikyte, J; Schemmer, P; Stiegler, P; Strupas, K, 2020)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Maneikyte, J1
Bausys, A1
Leber, B1
Feldbacher, N1
Hoefler, G1
Kolb-Lenz, D1
Strupas, K1
Stiegler, P1
Schemmer, P1
Cooper, RA1
James, RD1
Taylor, KJ1
Klishov, AA1

Reviews

1 review available for fluorouracil and Cardiac Rupture, Traumatic

ArticleYear
[Regulation of reactive and adaptive changes in skeletal muscle and cardiac muscle tissues].
    Arkhiv anatomii, gistologii i embriologii, 1977, Volume: 72, Issue:2

    Topics: Adaptation, Physiological; Animals; Autoradiography; Cell Differentiation; Fluorouracil; Heart; Hear

1977

Other Studies

2 other studies available for fluorouracil and Cardiac Rupture, Traumatic

ArticleYear
Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats.
    Nutrients, 2020, Aug-28, Volume: 12, Issue:9

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms

2020
Cardiac perforation associated with continuous infusional chemotherapy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1996, Volume: 8, Issue:6

    Topics: Antineoplastic Agents; Catheterization, Central Venous; Colonic Neoplasms; Fluorouracil; Heart Injur

1996
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