fluorouracil and Cardiac Rupture, Traumatic
fluorouracil has been researched along with Cardiac Rupture, Traumatic in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Glycine has been shown to protect livers from CTx-induced injury and oxidative stress, and it reduces platelet aggregation and improves microperfusion." | 5.56 | Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats. ( Bausys, A; Feldbacher, N; Hoefler, G; Kolb-Lenz, D; Leber, B; Maneikyte, J; Schemmer, P; Stiegler, P; Strupas, K, 2020) |
"The case history is reported of a 51-year-old man with metastatic colonic carcinoma who was receiving a continuous 5-fluorouracil infusion via a central venous catheter and who developed cardiac perforation and pericardial effusion." | 3.69 | Cardiac perforation associated with continuous infusional chemotherapy. ( Cooper, RA; James, RD; Taylor, KJ, 1996) |
"Glycine has been shown to protect livers from CTx-induced injury and oxidative stress, and it reduces platelet aggregation and improves microperfusion." | 1.56 | Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats. ( Bausys, A; Feldbacher, N; Hoefler, G; Kolb-Lenz, D; Leber, B; Maneikyte, J; Schemmer, P; Stiegler, P; Strupas, K, 2020) |
Research
Studies (3)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (33.33) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (33.33) | 2.80 |
Authors
Authors | Studies |
---|---|
Maneikyte, J | 1 |
Bausys, A | 1 |
Leber, B | 1 |
Feldbacher, N | 1 |
Hoefler, G | 1 |
Kolb-Lenz, D | 1 |
Strupas, K | 1 |
Stiegler, P | 1 |
Schemmer, P | 1 |
Cooper, RA | 1 |
James, RD | 1 |
Taylor, KJ | 1 |
Klishov, AA | 1 |
Reviews
1 review available for fluorouracil and Cardiac Rupture, Traumatic
Article | Year |
---|---|
[Regulation of reactive and adaptive changes in skeletal muscle and cardiac muscle tissues].
Topics: Adaptation, Physiological; Animals; Autoradiography; Cell Differentiation; Fluorouracil; Heart; Hear | 1977 |
Other Studies
2 other studies available for fluorouracil and Cardiac Rupture, Traumatic
Article | Year |
---|---|
Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms | 2020 |
Cardiac perforation associated with continuous infusional chemotherapy.
Topics: Antineoplastic Agents; Catheterization, Central Venous; Colonic Neoplasms; Fluorouracil; Heart Injur | 1996 |