Page last updated: 2024-10-27

fluorouracil and Cardiac Hypertrophy

fluorouracil has been researched along with Cardiac Hypertrophy in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shipman, KE1
Arnold, I1
Loprinzi, CL1
Carbone, PP1
Tormey, DC1
Rosenbaum, PR1
Caldwell, W1
Kline, JC1
Steeves, RA1
Ramirez, G1
Smith, FE1
Lane, M1
Hudgins, PT1

Other Studies

3 other studies available for fluorouracil and Cardiac Hypertrophy

ArticleYear
Case of epirubicin-induced cardiomyopathy in familial cardiomyopathy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-20, Volume: 29, Issue:18

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Breast Neoplasms; Carcinoma, Ductal, Breast; Cardiac

2011
Aggressive combined modality therapy for advanced local-regional breast carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiomegaly; Combine

1984
Conservative management of malignant pericardial effusion.
    Cancer, 1974, Volume: 33, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Cardiomegaly; Female; Fluorouracil; Follow-Up Studies

1974