Page last updated: 2024-10-27

fluorouracil and Carcinoma, Papillary

fluorouracil has been researched along with Carcinoma, Papillary in 30 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Carcinoma, Papillary: A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"We report an extremely long duration of chemotherapy with ixabepilone and capecitabine (42 cycles) in a patient with triple-negative metastatic breast cancer previously treated with anthracyclines and taxanes."7.76Long-lasting control of triple-negative metastatic breast cancer with the novel drug combination ixabepilone and capecitabine--case report. ( Bosković, L; Curić, Z; Lukić, B; Mise, BP; Tica, I; Vrdoljak, E, 2010)
"We report an extremely long duration of chemotherapy with ixabepilone and capecitabine (42 cycles) in a patient with triple-negative metastatic breast cancer previously treated with anthracyclines and taxanes."3.76Long-lasting control of triple-negative metastatic breast cancer with the novel drug combination ixabepilone and capecitabine--case report. ( Bosković, L; Curić, Z; Lukić, B; Mise, BP; Tica, I; Vrdoljak, E, 2010)
"Capecitabine has clinical activity in MRCC patients who have non-clear cell histology and a good or intermediate prognosis."2.77Phase II, multicenter, uncontrolled trial of single-agent capecitabine in patients with non-clear cell metastatic renal cell carcinoma. ( Demidov, L; Galchenko, V; Kharkevich, G; Naidzionak, U; Petenko, N; Sinelnikov, I; Tsimafeyeu, I, 2012)
"Male breast cancer is a rare disease and the incidence has increased over the past 25 years."2.44[Clinical research advancement on male breast cancer]. ( Guo, XT; Liu, WC; Xue, Y, 2007)
"The role of aromatase inhibitors combined with gonadotropin-releasing hormone analog in metastatic male breast cancer patients remains unknown."1.39Letrozole combined with gonadotropin-releasing hormone analog for metastatic male breast cancer. ( Barba, M; Del Medico, P; Di Lauro, L; Giannarelli, D; Laudadio, L; Maugeri-Saccà, M; Pizzuti, L; Sergi, D; Tomao, S; Vici, P, 2013)
"One hundred and fourteen cases of breast cancer with NA therapy were analyzed and clinical data were collected from March 2007 to December 2010."1.37[Primary systemic therapy in breast cancer patients (2007-2010)]. ( Farkas, R; Horváth, OP; Kálmán, E; Kovács, G; Kövér, E; Pavlovics, G; Szalai, G; Tizedes, G; Zapf, I, 2011)
"All cases of breast carcinoma diagnosed during the period from 1989 to 2001 were retrospectively reviewed."1.34[Diagnosis and prognosis study of breast carcinoma with micropapillary component]. ( Chen, L; Fan, Y; Fu, L; Guo, XJ; Lang, RG; Sun, YL, 2007)
" We dosed 6 cycles of FEC chemotherapy (CPA 800 mg, EPI 80 mg, 5-FU 750 mg/body x 1 cycle)."1.33[A case of breast cancer detected by MRI mammography after Hollywood syndrome]. ( Amano, S; Enomoto, K; Kitajima, A; Matsuo, S; Negishi, N; Nemoto, N; Oinuma, T; Sakurai, K, 2005)
"Capecitabine has not been tested against thyroid cancers, and it is not known to what extent thyroid cancers express TP, TS or DPD."1.32Enzyme expression profiles suggest the novel tumor-activated fluoropyrimidine carbamate capecitabine (Xeloda) might be effective against papillary thyroid cancers of children and young adults. ( Bauer, A; Francis, GL; Helms, A; Patel, A; Pluim, T; Tuttle, RM, 2004)
"In 41 cases of primary breast cancer preoperative treatment was performed using 2 methods consisting CPA + FT-207 (5-FUDS) (for Group I) and CPA + FT-207 (5-FUDS) + MMC (for Group II) to determine clinical and histological efficacies."1.27[Clinical study on preoperative chemotherapy of primary breast cancer. 2--A comparative study of CPA + FT-207 (5-FUDS) and CPA + FT-207 (5-FUDS) + MMC]. ( Andoh, H; Fujii, Y; Gotoh, M; Hagiwara, H; Hara, Y; Kataoka, J; Kobayashi, T; Komuro, K; Nagasaki, Y; Nagayama, A; Nakamura, K; Nakamura, R, 1983)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199011 (36.67)18.7374
1990's3 (10.00)18.2507
2000's7 (23.33)29.6817
2010's9 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, H1
Wang, X1
Zhang, C1
Cheng, Y1
Yu, M1
Zhao, K1
Ge, W1
Cai, A1
Zhang, Y1
Han, F1
Hu, Y1
Di Lauro, L1
Vici, P1
Del Medico, P1
Laudadio, L1
Tomao, S1
Giannarelli, D1
Pizzuti, L1
Sergi, D1
Barba, M1
Maugeri-Saccà, M1
Kimura, M1
Tominaga, T1
Takatsuka, Y1
Toi, M1
Abe, R1
Koyama, H1
Takashima, S1
Nomura, Y1
Miura, S1
Kimijima, I1
Tashiro, H1
Ohashi, Y1
Swartz, MJ1
Hsu, CC1
Pawlik, TM1
Winter, J1
Hruban, RH1
Guler, M1
Schulick, RD1
Cameron, JL1
Laheru, DA1
Wolfgang, CL1
Herman, JM1
Montagna, E1
Cancello, G1
Torrisi, R1
Rizzo, S1
Scarano, E1
Colleoni, M1
Vrdoljak, E1
Mise, BP1
Lukić, B1
Curić, Z1
Bosković, L1
Tica, I1
Tsimafeyeu, I1
Demidov, L1
Kharkevich, G1
Petenko, N1
Galchenko, V1
Sinelnikov, I1
Naidzionak, U1
Zapf, I1
Tizedes, G1
Pavlovics, G1
Kovács, G1
Kálmán, E1
Szalai, G1
Kövér, E1
Farkas, R1
Horváth, OP1
Peled, Y1
Levavi, H1
Krissi, H1
Weill, Y1
Sabah, G1
Eitan, R1
Misaki, T1
Iwata, M1
Iida, Y1
Kasagi, K1
Konishi, J1
LYTTON, B1
MARK, JB1
HARVARD, BM1
ESQUIVEL, EL1
MACKENZIE, AR1
WHITMORE, WF1
Patel, A1
Pluim, T1
Helms, A1
Bauer, A1
Tuttle, RM1
Francis, GL1
Kitajima, A1
Amano, S1
Sakurai, K1
Enomoto, K1
Matsuo, S1
Negishi, N1
Oinuma, T1
Nemoto, N1
Nio, Y1
Toga, T1
Maruyama, R1
Fukushima, M1
Chen, L1
Fan, Y1
Lang, RG1
Guo, XJ1
Sun, YL1
Fu, L1
Xue, Y1
Guo, XT1
Liu, WC1
Tsunoda-Shimizu, H1
Hayashi, N1
Hamaoka, T1
Kawasaki, T1
Tsugawa, K1
Yagata, H1
Kikuchi, M1
Suzuki, K1
Nakamura, S1
Komuro, K1
Hara, Y1
Fujii, Y1
Nagayama, A1
Kobayashi, T1
Gotoh, M1
Hagiwara, H1
Nakamura, R1
Nagasaki, Y1
Kataoka, J1
Andoh, H1
Nakamura, K1
Strauss, JF1
Hirsch, VJ1
Rubey, CN1
Pollock, M1
Hugosson, J1
Bergdahl, S1
Carlsson, G1
Frösing, R1
Norlén, L1
Gustavsson, B1
Rózewicki, S1
Rzepka, I1
Górski, H1
Machida, S1
Yoshida, O1
Abe, M1
Carson, TE1
Sbalzarini, G1
Pandolfi, C1
Labadini, A1
Stachura, J1
Popiela, T1
Pietroń, M1
Tomaszewska, R1
Kulig, J1
Nowak, K1
Saito, Y1
Uchiyama, G1
Hayashi, S1
Araki, T1
Hihara, T1
Seto, K1
Hayakawa, K1
Ohnishi, M1
Kambayashi, H1
Oyama, T1
Bargman, H1
Izsak, FC1
Eylan, E1
Gazith, A1
Shapiro, J1
Naharin, S1
Raanani, C1
Tomiyama, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Study of Capecitabine in Metastatic Non-clear Cell Renal Cell Carcinoma Patients[NCT01182142]Phase 251 participants (Anticipated)Interventional2007-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for fluorouracil and Carcinoma, Papillary

ArticleYear
[Clinical research advancement on male breast cancer].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:10

    Topics: Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis

2007

Trials

3 trials available for fluorouracil and Carcinoma, Papillary

ArticleYear
Randomized trial of cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil with node-positive breast cancer in Japan.
    Breast cancer (Tokyo, Japan), 2010, Volume: 17, Issue:3

    Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Adult; Antineoplastic Combined Chemotherapy Protocols; Ax

2010
Phase II, multicenter, uncontrolled trial of single-agent capecitabine in patients with non-clear cell metastatic renal cell carcinoma.
    American journal of clinical oncology, 2012, Volume: 35, Issue:3

    Topics: Administration, Oral; Adult; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Papillary; Ca

2012
Effects of intravesical instillation of 5-fluorouracil and interferon in patients with recurrent superficial urinary bladder carcinoma. A clinical and pharmacodynamic study.
    Scandinavian journal of urology and nephrology, 1997, Volume: 31, Issue:4

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy P

1997

Other Studies

26 other studies available for fluorouracil and Carcinoma, Papillary

ArticleYear
HDAC1-induced epigenetic silencing of ASPP2 promotes cell motility, tumour growth and drug resistance in renal cell carcinoma.
    Cancer letters, 2018, 09-28, Volume: 432

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Papil

2018
Letrozole combined with gonadotropin-releasing hormone analog for metastatic male breast cancer.
    Breast cancer research and treatment, 2013, Volume: 141, Issue:1

    Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inh

2013
Adjuvant chemoradiotherapy after pancreatic resection for invasive carcinoma associated with intraductal papillary mucinous neoplasm of the pancreas.
    International journal of radiation oncology, biology, physics, 2010, Mar-01, Volume: 76, Issue:3

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antimetabolites, Ant

2010
Lapatinib and metronomic capecitabine combination in an HER2-positive inflammatory breast cancer patient: a case report.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Carcinoma, Papillary

2010
Long-lasting control of triple-negative metastatic breast cancer with the novel drug combination ixabepilone and capecitabine--case report.
    Onkologie, 2010, Volume: 33, Issue:1-2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Capecitabine; C

2010
[Primary systemic therapy in breast cancer patients (2007-2010)].
    Magyar sebeszet, 2011, Volume: 64, Issue:5

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms;

2011
The use of Fluorouracil (5-FU) and leucovorin in women with heavily pretreated advanced ovarian carcinoma.
    American journal of clinical oncology, 2013, Volume: 36, Issue:5

    Topics: Adenocarcinoma, Mucinous; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Papillary

2013
Chemo-radionuclide therapy for thyroid cancer: initial experimental study with cultured cells.
    Annals of nuclear medicine, 2002, Volume: 16, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Papillary; Cell Survival; Cisplatin; Dose

2002
Continuous intraarterial chemotherapy in advanced bladder cancer. A preliminary report.
    Connecticut medicine, 1963, Volume: 27

    Topics: Carcinoma; Carcinoma, Papillary; Carcinoma, Transitional Cell; Fluorouracil; Humans; Neoplasms; Urin

1963
TREATMENT OF BLADDER TUMORS BY INSTILLATION OF THIO-TEPA, ACTINOMYCIN D, OR 5-FLUOROURACIL.
    Investigative urology, 1965, Volume: 2

    Topics: Carcinoma; Carcinoma, Papillary; Dactinomycin; Drug Therapy; Fluorouracil; Humans; Neoplasms; Thiote

1965
Enzyme expression profiles suggest the novel tumor-activated fluoropyrimidine carbamate capecitabine (Xeloda) might be effective against papillary thyroid cancers of children and young adults.
    Cancer chemotherapy and pharmacology, 2004, Volume: 53, Issue:5

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Papillary; Child; Deoxy

2004
[A case of breast cancer detected by MRI mammography after Hollywood syndrome].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Implants; Breast Neoplasms; C

2005
Expression of orotate phosphoribosyl transferase in human pancreatic cancer: implication for the efficacy of uracil and tegafur-based adjuvant chemotherapy.
    Oncology reports, 2007, Volume: 18, Issue:1

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Proto

2007
[Diagnosis and prognosis study of breast carcinoma with micropapillary component].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2007, Volume: 36, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone N

2007
Determining the morphological features of breast cancer and predicting the effects of neoadjuvant chemotherapy via diagnostic breast imaging.
    Breast cancer (Tokyo, Japan), 2008, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carci

2008
[Clinical study on preoperative chemotherapy of primary breast cancer. 2--A comparative study of CPA + FT-207 (5-FUDS) and CPA + FT-207 (5-FUDS) + MMC].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:6

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating;

1983
Resection of a solid and papillary epithelial neoplasm of the pancreas following treatment with cis-platinum and 5-fluorouracil: a case report.
    Medical and pediatric oncology, 1993, Volume: 21, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Papillary; Cisplatin; Combine

1993
[Early results of polychemotherapy in advanced ovarian tumors].
    Ginekologia polska, 1979, Volume: 50, Issue:11

    Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Adult; Aged; Carcinoma, Papillary; Cyclophosphamide; Cyst

1979
[Radiotherapy of bladder neoplasms, with special reference to the combined therapy with 5-FU].
    Nihon rinsho. Japanese journal of clinical medicine, 1977, Apr-10, Volume: 35, Issue:4

    Topics: Adult; Aged; Carcinoma, Papillary; Female; Fluorouracil; Humans; Male; Middle Aged; Urinary Bladder

1977
Verrucous carcinoma of the penis. Successful treatment with cryosurgery and topical fluorouracil therapy.
    Archives of dermatology, 1978, Volume: 114, Issue:10

    Topics: Administration, Topical; Carcinoma, Papillary; Cryosurgery; Fluorouracil; Humans; Male; Middle Aged;

1978
[Platelet aggregation during adjuvant chemotherapy with CMF].
    Minerva medica, 1991, Volume: 82, Issue:6

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol

1991
Cytology of solid and papillary epithelial neoplasms of the pancreas: a case report.
    Diagnostic cytopathology, 1988, Volume: 4, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carcinoma, Papillary; Cytodia

1988
[A case report of verrucous carcinoma of the lower molar region, effectively treated with preoperative irradiation and continuous intra-arterial infusion of fluorouracil].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1987, Jan-25, Volume: 47, Issue:1

    Topics: Aged; Carcinoma, Papillary; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arteri

1987
Pseudoepitheliomatous, keratotic, and micaceous balanitis.
    Cutis, 1985, Volume: 35, Issue:1

    Topics: Administration, Topical; Aged; Balanitis; Carcinoma, Papillary; Fluorouracil; Humans; Male; Penile N

1985
Growth inhibiting effects of cytotoxic agents on human tumor and tumor-bearing normal tissue in vitro.
    European journal of cancer, 1971, Volume: 7, Issue:1

    Topics: Adenocarcinoma, Mucinous; Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Carcinoma, Intra

1971
[Effects of intravesical instillation of antitumor agents on bladder cancer].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1972, Volume: 63, Issue:7

    Topics: Aged; Carcinoma, Papillary; Carcinoma, Transitional Cell; Female; Fluorouracil; Humans; Injections;

1972