fluorouracil has been researched along with Carcinoma, Papillary in 30 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Carcinoma, Papillary: A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report an extremely long duration of chemotherapy with ixabepilone and capecitabine (42 cycles) in a patient with triple-negative metastatic breast cancer previously treated with anthracyclines and taxanes." | 7.76 | Long-lasting control of triple-negative metastatic breast cancer with the novel drug combination ixabepilone and capecitabine--case report. ( Bosković, L; Curić, Z; Lukić, B; Mise, BP; Tica, I; Vrdoljak, E, 2010) |
| "We report an extremely long duration of chemotherapy with ixabepilone and capecitabine (42 cycles) in a patient with triple-negative metastatic breast cancer previously treated with anthracyclines and taxanes." | 3.76 | Long-lasting control of triple-negative metastatic breast cancer with the novel drug combination ixabepilone and capecitabine--case report. ( Bosković, L; Curić, Z; Lukić, B; Mise, BP; Tica, I; Vrdoljak, E, 2010) |
| "Capecitabine has clinical activity in MRCC patients who have non-clear cell histology and a good or intermediate prognosis." | 2.77 | Phase II, multicenter, uncontrolled trial of single-agent capecitabine in patients with non-clear cell metastatic renal cell carcinoma. ( Demidov, L; Galchenko, V; Kharkevich, G; Naidzionak, U; Petenko, N; Sinelnikov, I; Tsimafeyeu, I, 2012) |
| "Male breast cancer is a rare disease and the incidence has increased over the past 25 years." | 2.44 | [Clinical research advancement on male breast cancer]. ( Guo, XT; Liu, WC; Xue, Y, 2007) |
| "The role of aromatase inhibitors combined with gonadotropin-releasing hormone analog in metastatic male breast cancer patients remains unknown." | 1.39 | Letrozole combined with gonadotropin-releasing hormone analog for metastatic male breast cancer. ( Barba, M; Del Medico, P; Di Lauro, L; Giannarelli, D; Laudadio, L; Maugeri-Saccà, M; Pizzuti, L; Sergi, D; Tomao, S; Vici, P, 2013) |
| "One hundred and fourteen cases of breast cancer with NA therapy were analyzed and clinical data were collected from March 2007 to December 2010." | 1.37 | [Primary systemic therapy in breast cancer patients (2007-2010)]. ( Farkas, R; Horváth, OP; Kálmán, E; Kovács, G; Kövér, E; Pavlovics, G; Szalai, G; Tizedes, G; Zapf, I, 2011) |
| "All cases of breast carcinoma diagnosed during the period from 1989 to 2001 were retrospectively reviewed." | 1.34 | [Diagnosis and prognosis study of breast carcinoma with micropapillary component]. ( Chen, L; Fan, Y; Fu, L; Guo, XJ; Lang, RG; Sun, YL, 2007) |
| " We dosed 6 cycles of FEC chemotherapy (CPA 800 mg, EPI 80 mg, 5-FU 750 mg/body x 1 cycle)." | 1.33 | [A case of breast cancer detected by MRI mammography after Hollywood syndrome]. ( Amano, S; Enomoto, K; Kitajima, A; Matsuo, S; Negishi, N; Nemoto, N; Oinuma, T; Sakurai, K, 2005) |
| "Capecitabine has not been tested against thyroid cancers, and it is not known to what extent thyroid cancers express TP, TS or DPD." | 1.32 | Enzyme expression profiles suggest the novel tumor-activated fluoropyrimidine carbamate capecitabine (Xeloda) might be effective against papillary thyroid cancers of children and young adults. ( Bauer, A; Francis, GL; Helms, A; Patel, A; Pluim, T; Tuttle, RM, 2004) |
| "In 41 cases of primary breast cancer preoperative treatment was performed using 2 methods consisting CPA + FT-207 (5-FUDS) (for Group I) and CPA + FT-207 (5-FUDS) + MMC (for Group II) to determine clinical and histological efficacies." | 1.27 | [Clinical study on preoperative chemotherapy of primary breast cancer. 2--A comparative study of CPA + FT-207 (5-FUDS) and CPA + FT-207 (5-FUDS) + MMC]. ( Andoh, H; Fujii, Y; Gotoh, M; Hagiwara, H; Hara, Y; Kataoka, J; Kobayashi, T; Komuro, K; Nagasaki, Y; Nagayama, A; Nakamura, K; Nakamura, R, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (36.67) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 9 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, H | 1 |
| Wang, X | 1 |
| Zhang, C | 1 |
| Cheng, Y | 1 |
| Yu, M | 1 |
| Zhao, K | 1 |
| Ge, W | 1 |
| Cai, A | 1 |
| Zhang, Y | 1 |
| Han, F | 1 |
| Hu, Y | 1 |
| Di Lauro, L | 1 |
| Vici, P | 1 |
| Del Medico, P | 1 |
| Laudadio, L | 1 |
| Tomao, S | 1 |
| Giannarelli, D | 1 |
| Pizzuti, L | 1 |
| Sergi, D | 1 |
| Barba, M | 1 |
| Maugeri-Saccà, M | 1 |
| Kimura, M | 1 |
| Tominaga, T | 1 |
| Takatsuka, Y | 1 |
| Toi, M | 1 |
| Abe, R | 1 |
| Koyama, H | 1 |
| Takashima, S | 1 |
| Nomura, Y | 1 |
| Miura, S | 1 |
| Kimijima, I | 1 |
| Tashiro, H | 1 |
| Ohashi, Y | 1 |
| Swartz, MJ | 1 |
| Hsu, CC | 1 |
| Pawlik, TM | 1 |
| Winter, J | 1 |
| Hruban, RH | 1 |
| Guler, M | 1 |
| Schulick, RD | 1 |
| Cameron, JL | 1 |
| Laheru, DA | 1 |
| Wolfgang, CL | 1 |
| Herman, JM | 1 |
| Montagna, E | 1 |
| Cancello, G | 1 |
| Torrisi, R | 1 |
| Rizzo, S | 1 |
| Scarano, E | 1 |
| Colleoni, M | 1 |
| Vrdoljak, E | 1 |
| Mise, BP | 1 |
| Lukić, B | 1 |
| Curić, Z | 1 |
| Bosković, L | 1 |
| Tica, I | 1 |
| Tsimafeyeu, I | 1 |
| Demidov, L | 1 |
| Kharkevich, G | 1 |
| Petenko, N | 1 |
| Galchenko, V | 1 |
| Sinelnikov, I | 1 |
| Naidzionak, U | 1 |
| Zapf, I | 1 |
| Tizedes, G | 1 |
| Pavlovics, G | 1 |
| Kovács, G | 1 |
| Kálmán, E | 1 |
| Szalai, G | 1 |
| Kövér, E | 1 |
| Farkas, R | 1 |
| Horváth, OP | 1 |
| Peled, Y | 1 |
| Levavi, H | 1 |
| Krissi, H | 1 |
| Weill, Y | 1 |
| Sabah, G | 1 |
| Eitan, R | 1 |
| Misaki, T | 1 |
| Iwata, M | 1 |
| Iida, Y | 1 |
| Kasagi, K | 1 |
| Konishi, J | 1 |
| LYTTON, B | 1 |
| MARK, JB | 1 |
| HARVARD, BM | 1 |
| ESQUIVEL, EL | 1 |
| MACKENZIE, AR | 1 |
| WHITMORE, WF | 1 |
| Patel, A | 1 |
| Pluim, T | 1 |
| Helms, A | 1 |
| Bauer, A | 1 |
| Tuttle, RM | 1 |
| Francis, GL | 1 |
| Kitajima, A | 1 |
| Amano, S | 1 |
| Sakurai, K | 1 |
| Enomoto, K | 1 |
| Matsuo, S | 1 |
| Negishi, N | 1 |
| Oinuma, T | 1 |
| Nemoto, N | 1 |
| Nio, Y | 1 |
| Toga, T | 1 |
| Maruyama, R | 1 |
| Fukushima, M | 1 |
| Chen, L | 1 |
| Fan, Y | 1 |
| Lang, RG | 1 |
| Guo, XJ | 1 |
| Sun, YL | 1 |
| Fu, L | 1 |
| Xue, Y | 1 |
| Guo, XT | 1 |
| Liu, WC | 1 |
| Tsunoda-Shimizu, H | 1 |
| Hayashi, N | 1 |
| Hamaoka, T | 1 |
| Kawasaki, T | 1 |
| Tsugawa, K | 1 |
| Yagata, H | 1 |
| Kikuchi, M | 1 |
| Suzuki, K | 1 |
| Nakamura, S | 1 |
| Komuro, K | 1 |
| Hara, Y | 1 |
| Fujii, Y | 1 |
| Nagayama, A | 1 |
| Kobayashi, T | 1 |
| Gotoh, M | 1 |
| Hagiwara, H | 1 |
| Nakamura, R | 1 |
| Nagasaki, Y | 1 |
| Kataoka, J | 1 |
| Andoh, H | 1 |
| Nakamura, K | 1 |
| Strauss, JF | 1 |
| Hirsch, VJ | 1 |
| Rubey, CN | 1 |
| Pollock, M | 1 |
| Hugosson, J | 1 |
| Bergdahl, S | 1 |
| Carlsson, G | 1 |
| Frösing, R | 1 |
| Norlén, L | 1 |
| Gustavsson, B | 1 |
| Rózewicki, S | 1 |
| Rzepka, I | 1 |
| Górski, H | 1 |
| Machida, S | 1 |
| Yoshida, O | 1 |
| Abe, M | 1 |
| Carson, TE | 1 |
| Sbalzarini, G | 1 |
| Pandolfi, C | 1 |
| Labadini, A | 1 |
| Stachura, J | 1 |
| Popiela, T | 1 |
| Pietroń, M | 1 |
| Tomaszewska, R | 1 |
| Kulig, J | 1 |
| Nowak, K | 1 |
| Saito, Y | 1 |
| Uchiyama, G | 1 |
| Hayashi, S | 1 |
| Araki, T | 1 |
| Hihara, T | 1 |
| Seto, K | 1 |
| Hayakawa, K | 1 |
| Ohnishi, M | 1 |
| Kambayashi, H | 1 |
| Oyama, T | 1 |
| Bargman, H | 1 |
| Izsak, FC | 1 |
| Eylan, E | 1 |
| Gazith, A | 1 |
| Shapiro, J | 1 |
| Naharin, S | 1 |
| Raanani, C | 1 |
| Tomiyama, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Study of Capecitabine in Metastatic Non-clear Cell Renal Cell Carcinoma Patients[NCT01182142] | Phase 2 | 51 participants (Anticipated) | Interventional | 2007-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fluorouracil and Carcinoma, Papillary
| Article | Year |
|---|---|
[Clinical research advancement on male breast cancer].
Topics: Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis | 2007 |
3 trials available for fluorouracil and Carcinoma, Papillary
| Article | Year |
|---|---|
Randomized trial of cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil with node-positive breast cancer in Japan.
Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Adult; Antineoplastic Combined Chemotherapy Protocols; Ax | 2010 |
Phase II, multicenter, uncontrolled trial of single-agent capecitabine in patients with non-clear cell metastatic renal cell carcinoma.
Topics: Administration, Oral; Adult; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Papillary; Ca | 2012 |
Effects of intravesical instillation of 5-fluorouracil and interferon in patients with recurrent superficial urinary bladder carcinoma. A clinical and pharmacodynamic study.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy P | 1997 |
26 other studies available for fluorouracil and Carcinoma, Papillary
| Article | Year |
|---|---|
HDAC1-induced epigenetic silencing of ASPP2 promotes cell motility, tumour growth and drug resistance in renal cell carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Papil | 2018 |
Letrozole combined with gonadotropin-releasing hormone analog for metastatic male breast cancer.
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inh | 2013 |
Adjuvant chemoradiotherapy after pancreatic resection for invasive carcinoma associated with intraductal papillary mucinous neoplasm of the pancreas.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antimetabolites, Ant | 2010 |
Lapatinib and metronomic capecitabine combination in an HER2-positive inflammatory breast cancer patient: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Carcinoma, Papillary | 2010 |
Long-lasting control of triple-negative metastatic breast cancer with the novel drug combination ixabepilone and capecitabine--case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Capecitabine; C | 2010 |
[Primary systemic therapy in breast cancer patients (2007-2010)].
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; | 2011 |
The use of Fluorouracil (5-FU) and leucovorin in women with heavily pretreated advanced ovarian carcinoma.
Topics: Adenocarcinoma, Mucinous; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Papillary | 2013 |
Chemo-radionuclide therapy for thyroid cancer: initial experimental study with cultured cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Papillary; Cell Survival; Cisplatin; Dose | 2002 |
Continuous intraarterial chemotherapy in advanced bladder cancer. A preliminary report.
Topics: Carcinoma; Carcinoma, Papillary; Carcinoma, Transitional Cell; Fluorouracil; Humans; Neoplasms; Urin | 1963 |
TREATMENT OF BLADDER TUMORS BY INSTILLATION OF THIO-TEPA, ACTINOMYCIN D, OR 5-FLUOROURACIL.
Topics: Carcinoma; Carcinoma, Papillary; Dactinomycin; Drug Therapy; Fluorouracil; Humans; Neoplasms; Thiote | 1965 |
Enzyme expression profiles suggest the novel tumor-activated fluoropyrimidine carbamate capecitabine (Xeloda) might be effective against papillary thyroid cancers of children and young adults.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Papillary; Child; Deoxy | 2004 |
[A case of breast cancer detected by MRI mammography after Hollywood syndrome].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Implants; Breast Neoplasms; C | 2005 |
Expression of orotate phosphoribosyl transferase in human pancreatic cancer: implication for the efficacy of uracil and tegafur-based adjuvant chemotherapy.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Proto | 2007 |
[Diagnosis and prognosis study of breast carcinoma with micropapillary component].
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone N | 2007 |
Determining the morphological features of breast cancer and predicting the effects of neoadjuvant chemotherapy via diagnostic breast imaging.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carci | 2008 |
[Clinical study on preoperative chemotherapy of primary breast cancer. 2--A comparative study of CPA + FT-207 (5-FUDS) and CPA + FT-207 (5-FUDS) + MMC].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; | 1983 |
Resection of a solid and papillary epithelial neoplasm of the pancreas following treatment with cis-platinum and 5-fluorouracil: a case report.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Papillary; Cisplatin; Combine | 1993 |
[Early results of polychemotherapy in advanced ovarian tumors].
Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Adult; Aged; Carcinoma, Papillary; Cyclophosphamide; Cyst | 1979 |
[Radiotherapy of bladder neoplasms, with special reference to the combined therapy with 5-FU].
Topics: Adult; Aged; Carcinoma, Papillary; Female; Fluorouracil; Humans; Male; Middle Aged; Urinary Bladder | 1977 |
Verrucous carcinoma of the penis. Successful treatment with cryosurgery and topical fluorouracil therapy.
Topics: Administration, Topical; Carcinoma, Papillary; Cryosurgery; Fluorouracil; Humans; Male; Middle Aged; | 1978 |
[Platelet aggregation during adjuvant chemotherapy with CMF].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol | 1991 |
Cytology of solid and papillary epithelial neoplasms of the pancreas: a case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carcinoma, Papillary; Cytodia | 1988 |
[A case report of verrucous carcinoma of the lower molar region, effectively treated with preoperative irradiation and continuous intra-arterial infusion of fluorouracil].
Topics: Aged; Carcinoma, Papillary; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arteri | 1987 |
Pseudoepitheliomatous, keratotic, and micaceous balanitis.
Topics: Administration, Topical; Aged; Balanitis; Carcinoma, Papillary; Fluorouracil; Humans; Male; Penile N | 1985 |
Growth inhibiting effects of cytotoxic agents on human tumor and tumor-bearing normal tissue in vitro.
Topics: Adenocarcinoma, Mucinous; Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Carcinoma, Intra | 1971 |
[Effects of intravesical instillation of antitumor agents on bladder cancer].
Topics: Aged; Carcinoma, Papillary; Carcinoma, Transitional Cell; Female; Fluorouracil; Humans; Injections; | 1972 |