fluorouracil has been researched along with Carcinoma, Mucoepidermoid in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Carcinoma, Mucoepidermoid: A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Response to anticancer therapy is believed to be directly related to the concentration of the anticancer drug in the tumor itself." | 2.76 | Increasing tumoral 5-fluorouracil concentrations during a 5-day continuous infusion: a microdialysis study. ( de Bruijn, P; Ghobadi Moghaddam-Helmantel, IM; Konings, IR; Loos, WJ; Mathijssen, RH; Sleijfer, S; van Dam, LM; Verweij, J; Wiemer, EA, 2011) |
| "The palliative effects on dysphagia of radiotherapy (RT) and chemotherapy (CT) were evaluated retrospectively and compared with the effect of the self-expanding stent, evaluated in the prospective study." | 1.29 | Palliation of dysphagia in patients with malignant esophageal strictures. Comparison of results of radiotherapy, chemotherapy and esophageal stent treatment. ( Albertsson, M; Cwikiel, M; Cwikiel, W, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamanaka, S | 1 |
| Suzuki, S | 1 |
| Ito, H | 1 |
| Sivasundaram, K | 1 |
| Hanamura, I | 1 |
| Okubo, I | 1 |
| Yoshikawa, K | 1 |
| Ono, S | 1 |
| Takahara, T | 1 |
| Satou, A | 1 |
| Tsuzuki, T | 1 |
| Ueda, R | 1 |
| Ogawa, T | 1 |
| Fujimoto, Y | 1 |
| Konings, IR | 1 |
| Sleijfer, S | 1 |
| Mathijssen, RH | 1 |
| de Bruijn, P | 1 |
| Ghobadi Moghaddam-Helmantel, IM | 1 |
| van Dam, LM | 1 |
| Wiemer, EA | 1 |
| Verweij, J | 1 |
| Loos, WJ | 1 |
| Song, BJ | 1 |
| Kwon, JH | 1 |
| Kim, JJ | 1 |
| Lee, JW | 1 |
| Min, SY | 1 |
| Lee, KB | 1 |
| Jang, JY | 1 |
| Ryu, JK | 1 |
| Cai, BL | 1 |
| Xu, XF | 1 |
| Fu, SM | 1 |
| Shen, LL | 1 |
| Zhang, J | 1 |
| Guan, SM | 1 |
| Wu, JZ | 1 |
| Cwikiel, M | 1 |
| Cwikiel, W | 1 |
| Albertsson, M | 1 |
1 trial available for fluorouracil and Carcinoma, Mucoepidermoid
| Article | Year |
|---|---|
Increasing tumoral 5-fluorouracil concentrations during a 5-day continuous infusion: a microdialysis study.
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Mucoepidermoid; Carcinoma, Non-Small-Cell Lung; Es | 2011 |
4 other studies available for fluorouracil and Carcinoma, Mucoepidermoid
| Article | Year |
|---|---|
Establishment of Mucoepidermoid Carcinoma Cell Lines from Surgical and Recurrence Biopsy Specimens.
Topics: Biopsy; Carcinoma, Mucoepidermoid; Cell Line, Tumor; Cisplatin; DNA-Binding Proteins; Fluorouracil; | 2023 |
[A case of primary mucoepidermoid carcinoma arising from the common bile duct].
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Mucoepidermoid; Cholangiopancreatography, Endoscop | 2011 |
Nuclear translocation of MRP1 contributes to multidrug resistance of mucoepidermoid carcinoma.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; ATP Binding Cas | 2011 |
Palliation of dysphagia in patients with malignant esophageal strictures. Comparison of results of radiotherapy, chemotherapy and esophageal stent treatment.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen | 1996 |