fluorouracil has been researched along with Carcinoma, Large Cell in 8 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Carcinoma, Large Cell: A tumor of undifferentiated (anaplastic) cells of large size. It is usually bronchogenic. (From Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, this study determined whether C3G alone or C3G combined with 5-fluorouracil (5-FU) inhibits human lung LCC." | 1.72 | The anticancer effects of cyanidin 3-O-glucoside combined with 5-fluorouracil on lung large-cell carcinoma in nude mice. ( Chang, GR; Liao, HJ; Lin, CF; Lin, TC; Liu, YW; Wu, CF; Wu, CY, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, CF | 1 |
| Wu, CY | 1 |
| Lin, CF | 1 |
| Liu, YW | 1 |
| Lin, TC | 1 |
| Liao, HJ | 1 |
| Chang, GR | 1 |
| Paydas, S | 1 |
| Bicakci, K | 1 |
| Yavuz, S | 1 |
| Nagasaki, T | 1 |
| Tsuchiya, T | 1 |
| Tagawa, T | 1 |
| Honda, S | 1 |
| Yamasaki, N | 1 |
| Miyazaki, T | 1 |
| Hidaka, S | 1 |
| Hayashi, T | 1 |
| Nagayasu, T | 1 |
| Lee, JJ | 1 |
| Han, JY | 1 |
| Lee, DH | 1 |
| Kim, HY | 1 |
| Chun, JH | 1 |
| Lee, HG | 1 |
| Yoon, SM | 1 |
| Lee, SY | 1 |
| Lee, JS | 1 |
| Ellis, PA | 1 |
| Talbot, DC | 1 |
| Nicolson, MC | 1 |
| Priest, K | 1 |
| Ashley, S | 1 |
| Smith, IE | 1 |
| Nakai, Y | 1 |
| Furuse, K | 1 |
| Ohta, M | 1 |
| Yamaguchi, Y | 1 |
| Fujii, M | 1 |
| Asakawa, M | 1 |
| Fukuoka, M | 1 |
| Yoshida, K | 1 |
| Niitani, H | 1 |
| Nakano, T | 1 |
| Ikegami, H | 1 |
| Nakamura, S | 1 |
| Kawase, T | 1 |
| Nishikawa, H | 1 |
| Yokota, S | 1 |
| Yoshida, M | 1 |
| Tachibana, T | 1 |
| Igarashi, T | 1 |
| Komuta, K | 1 |
| Higashino, K | 1 |
| Satoh, H | 1 |
| Ohtomo, M | 1 |
| Ishikawa, H | 1 |
| Kamma, H | 1 |
| Ohtsuka, M | 1 |
| Hasegawa, S | 1 |
4 trials available for fluorouracil and Carcinoma, Large Cell
| Article | Year |
|---|---|
A phase II trial of docetaxel plus capecitabine in patients with previously treated non-small cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma | 2006 |
A pilot study of mitomycin, cisplatin and continuous infusion 5-fluorouracil (MCF) in advanced non-small-cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; | 1995 |
Efficacy of a new 5-fluorouracil derivative, BOF-A2, in advanced non-small cell lung cancer. A multi-center phase II study.
Topics: Adenocarcinoma; Adult; Aged; Anemia; Antineoplastic Agents; Carcinoma, Large Cell; Carcinoma, Non-Sm | 1994 |
A phase II study of cisplatin, vindesine and continuously infused 5-fluorouracil in the treatment of advanced non-small-cell lung cancer. Osaka Lung Cancer Chemotherapy Study Group.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; Carcino | 1996 |
4 other studies available for fluorouracil and Carcinoma, Large Cell
| Article | Year |
|---|---|
The anticancer effects of cyanidin 3-O-glucoside combined with 5-fluorouracil on lung large-cell carcinoma in nude mice.
Topics: Animals; Anthocyanins; Carcinoma, Large Cell; Cell Line, Tumor; Fluorouracil; Glucosides; Inflammati | 2022 |
Dramatic response with capecitabine after cranial radiation to the brain parenchymal and leptomeningeal metastases from lung cancer.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Com | 2009 |
Analysis of 5-fluorouracil-related enzymes in pulmonary neuroendocrine carcinoma: differences in biological properties compared to epithelial carcinoma.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Carcinoma, Large Cell; Carcinoma, Neuroendocr | 2010 |
Inhibitory effect of combined administration with CPT-11 and 5-fluorouracil in vitro and in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Body Weigh | 1999 |