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fluorouracil and Carcinoma, Ehrlich Tumor

fluorouracil has been researched along with Carcinoma, Ehrlich Tumor in 176 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Carcinoma, Ehrlich Tumor: A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.

Research Excerpts

ExcerptRelevanceReference
"In order to acquire a biochemical fundamental knowledge on the enhancement of antitumor effect with 5-fluorouracil or its masked derivatives, this investigation was undertaken to determine the amounts of antineoplastic metabolic precursors formed from 5-fluorouracil-6-14C in the presence of various substrates by crude enzyme extracts from Ehrlich mouse ascites tumor cells and normal mouse liver."7.66Additive formation of antineoplastic 5-fluorouracil nucleosides from 5-fluorouracil by Ehrlich ascites tumor extracts in the presence of ribose 1-phosphate/uridine or deoxyribose 1-phosphate/deoxyuridine. ( Tamemasa, O; Tezuka, M, 1982)
"In order to acquire a biochemical fundamental knowledge on the enhancement of antitumor effect with 5-fluorouracil or its masked derivatives, this investigation was undertaken to determine the amounts of antineoplastic metabolic precursors formed from 5-fluorouracil-6-14C in the presence of various substrates by crude enzyme extracts from Ehrlich mouse ascites tumor cells and normal mouse liver."3.66Additive formation of antineoplastic 5-fluorouracil nucleosides from 5-fluorouracil by Ehrlich ascites tumor extracts in the presence of ribose 1-phosphate/uridine or deoxyribose 1-phosphate/deoxyuridine. ( Tamemasa, O; Tezuka, M, 1982)
"Antitumor activity of seven 5-fluorouracil derivatives having carbamoyl linkage with amino acid was examined against L-1210 leukemia, adenocarcinoma 755, ascites sarcoma 180, Ehrlich ascites carcinoma and Lewis lung carcinoma by oral administration."3.66Antitumor activity of 1-alkoxycarbonylalkylcarbamoyl-5-fluorouracil derivatives by oral administration. ( Ando, N; Hoshi, A; Iigo, M; Inomata, M; Kuretani, K, 1981)
" In combination therapy with mitomycin C, bleomycin, cyclophosphamide, and 5-fluorouracil, palmitoyldextran phosphate manifested strong synergistic effects against both Sarcoma 180 ascites and L1210 leukemic tumors."3.65Dextran derivatives in single and combination chemotherapy against transplantable mouse ascites and solid tumors. ( Kadowaki, M; Matsumoto, T; Mikami, T; Suzuki, M; Suzuki, S, 1977)
"158 cases of late gastric carcinoma (11 males and 47 females, age 30-70 years) were treated postoperatively with TCM prescriptions of strengthening the patient's resistance and dispelling the invading evil in combination with chemotherapy."2.67[Treatment of operated late gastric carcinoma with prescription of strengthening the patient's resistance and dispelling the invading evil in combination with chemotherapy: follow-up study of 158 patients and experimental study in animals]. ( Wang, GT, 1990)
" The LD50 (lethal dose 50%) value in mice was estimated to be higher than 5000 mg/kg (intraperitoneally)."1.51Toxicity and Antitumor Activity of a Thiophene-Acridine Hybrid. ( Andrade, C; Duarte, S; Farias, D; Ferreira, R; Lisboa, T; Lopes, AL; Magalhães, H; Medeiros, K; Moura, R; Reis, M; Ribeiro, J; Silva, D; Sobral, M, 2019)
" This leads to increased anti-tumour efficacy against SEC, with a reduction in adverse effects."1.48Polymeric nano-encapsulation of 5-fluorouracil enhances anti-cancer activity and ameliorates side effects in solid Ehrlich Carcinoma-bearing mice. ( El-Gizawy, SA; Faheem, AM; Goda, AE; Haggag, YA; McCarron, PA; Osman, MA; Shamloula, MM, 2018)
"Cytotoxicity studies were performed on Ehrlich ascites tumor (EAT) cell lines using MTT cell proliferation assay."1.36Development and characterization of hyaluronic acid decorated PLGA nanoparticles for delivery of 5-fluorouracil. ( Agarwal, A; Agrawal, GP; Agrawal, H; Jain, S; Mishra, AK; Mishra, P; Rai, G; Yadav, AK, 2010)
"Biflorin was active against both tumors with a very similar profile."1.34Antitumor activity of biflorin, an o-naphthoquinone isolated from Capraria biflora. ( Alves, AP; Bezerra, DP; Costa-Lotufo, LV; Fonseca, AM; Lemos, TL; Moraes, MO; Pereira, MR; Pessoa, C; Pessoa, OD; Vasconcellos, MC, 2007)
" Pharmacokinetic studies of 5-FU transdermal patch in rabbits showed half-life 95+/-0."1.34Transdermal delivery of 5-fluorouracil for induced ehrlich ascites carcinoma tumor in BALB/c mice and pharmacokinetic study. ( Chandrashekar, NS; Hiremath, SR, 2007)
" In addition, oral administration of CWSP concurrently with 5-fluorouracil (5-FU) or mitomycin C (MMC), significantly increased tumor regression as compared with the respective chemotherapy alone, illustrating the adjuvant effect of orally administered CWSP for tumor regression when combined with chemotherapeutic agents."1.31Antitumor and anticytopenic effects of aqueous extracts of propolis in combination with chemotherapeutic agents. ( Fujimiya, Y; Groveman, DS; Hayashi, I; Suzuki, I; Takaki, T, 2002)
" The dosage of the oral clinical use for human cancer of 5-FU, HCFU, 5'-DFUR and UFT as tegafur (FT) is 200-300mg/d, 600mg/d, 800-1,200mg/d and 300-600mg/d respectively."1.31Plasma, intestine and tumor levels of 5-fluorouracil in mice bearing L1210 ascites tumor following oral administration of 5-fluorouracil, UFT (mixed compound of tegafur and uracil), carmofur and 5'-deoxy-5-fluorouridine. ( Higashigawa, M; Kagawa, Y; Kakito, H; Kawasaki, H; Kojima, M; Ohkubo, T; Ooi, A; Sakurai, M, 2001)
"In this study, a new dosage form for antitumor agents--nanocapsules was prepared from biodegradable butylcyanoacrylate (BCA)."1.28[Studies of 5-fluorouracil nanocapsules]. ( Hu, J; Pan, WS, 1991)
" On the 9th day after transplantation, HCFU (150 mg/kg) and 5-FU (75 mg/kg) were administered with or without hyperthermia (43."1.27Enhancement of antitumor effects of 1-hexylcarbamoyl-5-fluorouracil combined with hyperthermia on Ehrlich ascites tumor in vivo and Nakahara-Fukuoka sarcoma cell in vitro. ( Takada, K; Tsumura, M; Yoshiga, K, 1988)
"Studies were undertaken with Ehrlich ascites tumor and bone marrow cells isolated from CF-1 mice."1.27Dihydrofluorouracil, a fluorouracil catabolite with antitumor activity in murine and human cells. ( Diasio, RB; Schuetz, JD; Sommadossi, JP; Wallace, HJ, 1985)
" 5'-dFUrd was a more effective antitumor agent and was less toxic over a wide dosage range (50 to 400 mg/kg) than the other agents tested as measured by: (a) the ability to prevent gross development of inoculated tumor; (b) 45-day survival; and (c) weight change over the treatment period."1.26Metabolism and biological activity of 5'-deoxy-5-fluorouridine, a novel fluoropyrimidine. ( Armstrong, RD; Diasio, RB, 1980)
"5-Fluorouracil was administered intraperitoneally for 7 consecutive days from day 9 to 15."1.26Combined treatment with anaerobic Corynebacterium liquefaciens and chemotherapeutics against solid tumor in mice. ( Hattori, T; Yamagata, S, 1977)
"5-Fluorouracil was administered intraperitoneally for 7 consecutive days beginning from the second day after inoculation of tumor cells."1.25Combination of non-specific immunopotentiation with Corynebacterium liquefaciens and chemotherapy in tumor-bearing mice. ( Hattori, T; Yamagata, S, 1975)

Research

Studies (176)

TimeframeStudies, this research(%)All Research%
pre-1990132 (75.00)18.7374
1990's17 (9.66)18.2507
2000's11 (6.25)29.6817
2010's15 (8.52)24.3611
2020's1 (0.57)2.80

Authors

AuthorsStudies
Sajadi, Z3
Almahmood, M1
Loeffler, LJ5
Hall, IH5
Yasumoto, M1
Yamawaki, I1
Marunaka, T1
Hashimoto, S1
Andreani, A2
Rambaldi, M2
Locatelli, A2
Bossa, R2
Fraccari, A2
Galatulas, I2
Kundu, NG1
Das, B1
Spears, CP1
Majumdar, A1
Kang, SI1
Sanyal, U1
Mitra, S1
Pal, P1
Chakraborti, SK1
Conway, GA1
Holshouser, MH1
Kashani, M1
Leoni, A1
Salvatore, G1
Sri Balasubashini, M1
Karthigayan, S1
Somasundaram, ST1
Balasubramanian, T1
Viswanathan, V1
Raveendran, P1
Menon, VP1
El-Far, M1
Elmegeed, GA1
Eskander, EF1
Rady, HM1
Tantawy, MA1
El-Shafei, A1
Fadda, AA1
Khalil, AM1
Ameen, TA1
Badria, FA1
Vendramini-Costa, DB1
de Castro, IB1
Ruiz, AL1
Marquissolo, C1
Pilli, RA1
de Carvalho, JE1
Reddy, DM1
Qazi, NA1
Sawant, SD1
Bandey, AH1
Srinivas, J1
Shankar, M1
Singh, SK1
Verma, M1
Chashoo, G1
Saxena, A1
Mondhe, D1
Saxena, AK1
Sethi, VK1
Taneja, SC1
Qazi, GN1
Sampath Kumar, HM1
El-Sayed, NS1
El-Bendary, ER2
El-Ashry, SM1
El-Kerdawy, MM2
Suthar, SK1
Jaiswal, V1
Lohan, S1
Bansal, S1
Chaudhary, A1
Tiwari, A1
Alex, AT1
Joesph, A1
Vijay Avin, BR1
Thirusangu, P1
Lakshmi Ranganatha, V1
Firdouse, A1
Prabhakar, BT1
Khanum, SA1
Gabr, MT1
El-Gohary, NS1
Ni, N1
Khwaja, S1
Fatima, K1
Hasanain, M1
Behera, C1
Kour, A1
Singh, A1
Luqman, S1
Sarkar, J1
Chanda, D1
Shanker, K1
Gupta, AK1
Mondhe, DM1
Negi, AS1
Aboalsoud, A1
El-Ghaiesh, SH1
Abd Elmonem, FF1
Salem, ML1
Abdel Rahman, MN1
Lisboa, T1
Silva, D1
Duarte, S1
Ferreira, R1
Andrade, C1
Lopes, AL1
Ribeiro, J1
Farias, D1
Moura, R1
Reis, M1
Medeiros, K1
Magalhães, H1
Sobral, M1
Gardouh, AR1
Barakat, BM1
Qushawy, MKE1
El-Kazzaz, AY1
Sami, MM1
Zaitone, SA1
Haggag, YA1
Osman, MA1
El-Gizawy, SA1
Goda, AE1
Shamloula, MM1
Faheem, AM1
McCarron, PA1
Soliman, NA1
Abd-Ellatif, RN1
ELSaadany, AA1
Shalaby, SM1
Bedeer, AE1
Jadhav, RL1
Magdum, CS1
Patil, MV1
Gaballah, HH1
Gaber, RA1
Mohamed, DA1
Aminin, DL1
Chaykina, EL1
Agafonova, IG1
Avilov, SA1
Kalinin, VI1
Stonik, VA1
Yadav, AK1
Agarwal, A1
Rai, G1
Mishra, P1
Jain, S1
Mishra, AK1
Agrawal, H1
Agrawal, GP1
Suzuki, I1
Hayashi, I1
Takaki, T1
Groveman, DS1
Fujimiya, Y1
Lin, Hs1
D'Rosario, T1
LINDNER, A2
OKADA, TA1
ROBERTS, E1
SKOLD, O1
MAGNUSSON, PH1
REVESZ, L1
KUTKAM, T1
SANKARANARAYANAN, K1
RUCKER, R1
ARRADONDO, J1
BOOTH, BA1
SARTORELLI, AC1
DIPAOLO, JA2
STROUD, AN1
MCDONALD, GO1
SVOBODA, BR1
BRUES, AM1
BROCKMAN, RW1
ANDERSON, EP1
RUTMAN, RJ1
PALMA, V1
REYERS-DEGLIINNOCENTI, I1
GARATTINI, S1
HEIDELBERGER, C4
BOOHAR, J1
BIRNIE, GD1
LANGEN, P3
PODOLSKY, S1
WASE, AW1
CARDENAS, J1
Mohamed, MM1
Mohamed, MA1
Fikry, NM1
Nyati, MK1
Feng, FY1
Kanade, VD1
Nayak, R1
Vasconcellos, MC1
Bezerra, DP1
Fonseca, AM1
Pereira, MR1
Lemos, TL1
Pessoa, OD1
Pessoa, C1
Moraes, MO1
Alves, AP1
Costa-Lotufo, LV1
Chandrashekar, NS1
Hiremath, SR1
Papoian, SA1
Kumkumadzhian, VA1
Glazer, RI1
Hartman, KD1
Armstrong, RD4
Diasio, RB6
Yamamoto, S1
Kawasaki, T1
Maurer-Schultze, B1
Miyoshi, T1
Ogawa, S1
Nobuhara, M1
Namba, M1
Bowen, D3
Bailey, BD1
Guernsey, LA1
Tamemasa, O7
Tezuka, M7
Kurokawa, T1
Iwasa, H1
Mimura, K1
Terashima, H1
Hiraide, H1
Mizoguchi, O1
Kanabe, S1
Tamaki, K1
Kadota, T1
Hatsuse, K1
Fujita, H2
Ueno, H1
Burns, ER1
Beland, SS1
Connolly, KM1
Kaplan, AM1
Klein, HO1
Wickramanayake, PD1
Voigtmann, R1
Löffler, T1
Mohr, R1
Oerkermann, H1
Chikaraishi, Y1
Mukai, M1
Den, N1
Yamazaki, Y1
Namiki, S1
Oda, S1
Nagao, K1
Shlemkevich, MP3
Omukai, Y1
Watanabe, S1
Nohno, T1
Senoo, T1
Saito, T1
Iurkiv, VA1
Melikhov, VI1
Miyazaki, S3
Ishii, K1
Sugibayashi, K2
Morimoto, Y3
Takada, M3
Belousova, AK2
Gerasimova, GK1
Young, JA1
Maruyama, Y1
Iigo, M3
Hoshi, A4
Inomata, M1
Ando, N1
Kuretani, K4
Mazumder, A1
Reztsova, VV1
Filov, VA3
Stukov, AN1
Fu, NW1
Quan, LP1
Akimoto, M1
Nadai, T1
Kato, Y1
Su, J1
Zhen, YC1
Qi, CQ1
Hu, JL1
Sur, P1
Ganguly, DK1
Wang, XW1
Xu, B1
Ojugo, AS1
McSheehy, PM2
Stubbs, M1
Alder, G1
Bashford, CL1
Maxwell, RJ2
Leach, MO1
Judson, IR1
Griffiths, JR2
Vartanian, LP1
Oltarzhevskaia, ND1
Vershinina, SF1
Gornaeva, GF1
Pustovalov, IuI1
Korovina, MA1
Ooi, A1
Ohkubo, T1
Higashigawa, M1
Kawasaki, H1
Kakito, H1
Kagawa, Y1
Kojima, M1
Sakurai, M1
Schumann, J1
Ehring, F1
Gohde, W1
Suzuki, M1
Mikami, T1
Kadowaki, M1
Matsumoto, T1
Suzuki, S1
Sviridenko, OP1
Egawa, J1
Ishioka, K1
Ogata, T1
Hecker, D1
Rose, H1
Powitz, A1
Goldman, ID2
Shani, J1
Wolf, W1
Schlesinger, T1
Atkins, HL1
Bradley-Moore, PR1
Casella, V1
Fowler, JS1
Greenberg, D1
Ido, T1
Lambrecht, RM1
MacGregor, R1
Mantescu, C1
Neirinckx, R1
Som, P1
Wolf, AP1
Wodinsky, I1
Meaney, K1
Okada, T2
Abrams, DN1
Knaus, EE1
Wiebe, LI1
White, JC1
Nakamura, A2
Hattori, T3
Yamagata, S3
Yoshida, M1
Takahashi, M1
Fujimoto, S1
Akao, T1
Itoh, B1
Koshizuka, I1
Koyano, K1
Myers, CE1
Young, RC1
Chabner, BA1
Niimoto, M1
Tohge, T1
Terao, H1
Kanamaru, R1
Wakui, A1
Bose, S1
Guha, S1
Paul, P1
Chowdhury, M1
Chowdhury, SR1
Sen, U1
Miyata, S1
Mikami, H1
Tai, M1
Hori, T1
Indap, MA3
Ambaye, RY3
Pan, WS1
Hu, J1
Lewin, F1
Skog, S1
Tribukait, B1
Ringborg, U1
Wang, GT1
Naik, SD1
Pertusa, J2
Pellicer, JA2
Alcober, V2
Levin, E1
Cherñavsky, A1
Takeuchi, S1
Sugiyama, M2
Hosokawa, M1
Koga, Y1
Kobayashi, H1
Taguchi, T1
Severin, E1
Hagenhoff, B1
Tsumura, M1
Yoshiga, K1
Takada, K1
Rao, XQ1
Chiba, Y2
Okada, S2
Borovskaia, TG1
Udintsev, SN1
Zueva, EP1
Fomina, TI1
Neĭshtadt, EL1
Osswald, H1
Herrmann, R1
Jones, GR1
Kitta, D1
Kunz, W1
Yamane, T1
Matsuoka, H1
Masuda, H1
Maehara, Y1
Sugimachi, K1
Inokuchi, K1
Hashiguchi, N1
Schuetz, JD1
Wallace, HJ1
Sommadossi, JP1
Knock, FE3
Galt, RM3
Oester, YT3
Sylvester, R2
Veselỳ, J1
Cihák, A1
Erbe, W1
Preiss, J1
Seifert, R1
Hilz, H1
Tret'iakov, AV2
Riazanov, EM2
Weitzel, G1
Warnecke, P1
Seeber, S1
Frankfurt, OS1
De Kloet, SR1
Andrean, BA1
Nakayama, M1
Mitsui, R1
Chang, YS1
Pedicelli, G1
Meĭren, DV1
Kopper, L1
Kiss, J1
Lapis, K1
Gale, GR1
Walker, EM1
Atkins, LM1
Smith, AB1
Meischen, SJ1
Marquillo, CL1
Esperbén, MT1
Pol'kina, RI1
Eiselein, J1
Biggs, MW1
Kuzela, S2
Krempaský, V2
Bohunická, E2
Ujházy, V2
Arlen, M1
Scherrer, JW1
Cukierman, J1
Nagin, F1
Levowitz, BS1
Kent, RJ1
Kanzawa, F1
Unemi, N1
Harima, K1
Daidai, Y1
Fujihara, H1
Fujii, S1
Gelderman, AH1
Lincoln, TL1
Cowie, DB1
Roberts, RB1
Reeves, WJ2
Seid, A1
Greenberg, DM1
Ishikawa, M1
Bollag, W1
Ondrus, B1
Oravec, C1
Cambelová, J1
Mériová, M1
Hasegawa, Y1
Irikura, T1
Mizuno, D1
Hong, CI1
Piantadosi, C2
Irvin, JL2
Oriuchi, T1
Hoshikawa, M1
Kondo, T1
Ichihashi, H1
Sasaki, S1
Kanamitsu, Y1
Bielka, H1
Stahl, J1
Chae, CB1
Shima, T1
Suzuki, K1
Kowollik, G1
Woods, MW1
Burk, D1
Gotto, AM1
Belkhode, ML1
Touster, O1
Cailleau, R1
Ballweg, H1
Schmähl, D1
von Wedelstaedt, E1
Bennett, LR1
Connon, FE1

Reviews

4 reviews available for fluorouracil and Carcinoma, Ehrlich Tumor

ArticleYear
BIOCHEMISTRY OF CANCER (METABOLIC ASPECTS).
    Annual review of biochemistry, 1963, Volume: 32

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tum

1963
Resistance of mammalian tumour cells toward pyrimidine analogues. A review.
    Oncology, 1973, Volume: 28, Issue:3

    Topics: Animals; Antimetabolites; Azacitidine; Azauridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Line;

1973
Fluorinated pyrimidines.
    Progress in nucleic acid research and molecular biology, 1965, Volume: 4

    Topics: Animals; Carcinoma, Ehrlich Tumor; Clinical Trials as Topic; DNA; DNA Viruses; Enzyme Induction; Flo

1965
[An inducible enzyme: tryptophan pyrrolase].
    Revista clinica espanola, 1971, Jan-31, Volume: 120, Issue:2

    Topics: Age Factors; Animals; Carcinoma, Ehrlich Tumor; Enzyme Induction; Enzyme Repression; Female; Fetus;

1971

Trials

2 trials available for fluorouracil and Carcinoma, Ehrlich Tumor

ArticleYear
[Treatment of operated late gastric carcinoma with prescription of strengthening the patient's resistance and dispelling the invading evil in combination with chemotherapy: follow-up study of 158 patients and experimental study in animals].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1990, Volume: 10, Issue:12

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Comb

1990
Fluorinated pyrimidines.
    Progress in nucleic acid research and molecular biology, 1965, Volume: 4

    Topics: Animals; Carcinoma, Ehrlich Tumor; Clinical Trials as Topic; DNA; DNA Viruses; Enzyme Induction; Flo

1965

Other Studies

171 other studies available for fluorouracil and Carcinoma, Ehrlich Tumor

ArticleYear
Antitumor and antiinflammatory agents: N-benzoyl-protected cyanomethyl esters of amino acids.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:11

    Topics: Acetonitriles; Amino Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents;

1979
Studies on antitumor agents, 2. Syntheses and antitumor activities of 1-(tetrahydro-2-furanyl)-5-fluorouracil and 1,3-bis(tetrahydro-2-furanyl)-5-fluorouracil.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:8

    Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Fluorouracil; Letha

1978
Antineoplastic agents. 2. Structure-activity studies on N-protected vinyl, 1,2-dibromoethyl, and cyanomethyl esters of several amino acids.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:12

    Topics: Acetonitriles; Amino Acids; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Ehrlic

1977
Potential antitumor agents. 21. Structure determination and antitumor activity of imidazo[2,1-b]thiazole guanylhydrazones.
    Journal of medicinal chemistry, 1992, Nov-27, Volume: 35, Issue:24

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Female; Hydrazones; Imidazoles; Mice; Mole

1992
Synthesis and biological activities of novel 5-(2-acylethynyl)uracils.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Ehrlich Tumor; Cell Division; Cell Survival; Dr

1990
New alpha-methylene gamma-lactone derivatives of substituted nucleic acid bases as potential anticancer agents.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Kinetics; Magnetic Resonance Spectroscopy;

1986
Synthesis and antitumor evaluation of selected 5,6-disubstituted 1(2)H-indazole-4,7-diones.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Division; Indazoles; Leukemia P388; M

1983
Synthesis and antitumor activity of a series of sulfone analogues of 1,4-naphthoquinone.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:7

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Cyclic S-Ox

1981
Antitumor agents: diazomethyl ketone and chloromethyl ketone analogues prepared from N-tosyl amino acids.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Diazomethane; Ketones; Leukemia P388; Male

1980
Potential antitumor agents. 24. Synthesis and pharmacological behavior of imidazo[2,1-b]thiazole guanylhydrazones bearing at least one chlorine.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cardiotonic Agents; Chlorine; Drug Screeni

1996
Fish venom (Pterios volitans) peptide reduces tumor burden and ameliorates oxidative stress in Ehrlich's ascites carcinoma xenografted mice.
    Bioorganic & medicinal chemistry letters, 2006, Dec-15, Volume: 16, Issue:24

    Topics: Animals; Carcinoma, Ehrlich Tumor; Fish Venoms; Fishes; Lethal Dose 50; Mice; Oxidative Stress; Tran

2006
Novel modified steroid derivatives of androstanolone as chemotherapeutic anti-cancer agents.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:10

    Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Ce

2009
Synthesis, antitumor evaluation, molecular modeling and quantitative structure-activity relationship (QSAR) of some novel arylazopyrazolodiazine and triazine analogs.
    Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14

    Topics: Animals; Antineoplastic Agents; Azo Compounds; Carcinoma, Ehrlich Tumor; Casein Kinase II; Catalytic

2009
Effect of goniothalamin on the development of Ehrlich solid tumor in mice.
    Bioorganic & medicinal chemistry, 2010, Sep-15, Volume: 18, Issue:18

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Carrageenan; Cel

2010
Design and synthesis of spiro derivatives of parthenin as novel anti-cancer agents.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Ehrlich Tumor; Cell C

2011
Synthesis and antitumor activity of new sulfonamide derivatives of thiadiazolo[3,2-a]pyrimidines.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; DNA; Drug Screening Assays, Antitumor; Mag

2011
Novel quinolone substituted thiazolidin-4-ones as anti-inflammatory, anticancer agents: design, synthesis and biological screening.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Ehrlich Tumor; Carra

2013
Synthesis and tumor inhibitory activity of novel coumarin analogs targeting angiogenesis and apoptosis.
    European journal of medicinal chemistry, 2014, Mar-21, Volume: 75

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Benzophenones; Carcinoma, Ehrlic

2014
Isatin-β-thiocarbohydrazones: Microwave-assisted synthesis, antitumor activity and structure-activity relationship.
    European journal of medicinal chemistry, 2017, Mar-10, Volume: 128

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Ehrlich Tumor; Cell Proliferation; Chlorocebus

2017
Antiproliferative efficacy of curcumin mimics through microtubule destabilization.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Line, Tumor; Cell Prolife

2018
The effect of low-dose naltrexone on solid Ehrlich carcinoma in mice: The role of OGFr, BCL2, and immune response.
    International immunopharmacology, 2020, Volume: 78

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Ehrlich Tumor; Cell L

2020
Toxicity and Antitumor Activity of a Thiophene-Acridine Hybrid.
    Molecules (Basel, Switzerland), 2019, Dec-24, Volume: 25, Issue:1

    Topics: Acridines; Animals; Antineoplastic Agents; Ascitic Fluid; Biomarkers; Carcinoma, Ehrlich Tumor; Cell

2019
Antitumor activity of a molecularly imprinted nanopreparation of 5-flurouracil against Ehrlich's carcinoma solid tumors grown in mice: Comparison to free 5-flurouracil.
    Chemico-biological interactions, 2018, Nov-01, Volume: 295

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Proliferation; Dose

2018
Polymeric nano-encapsulation of 5-fluorouracil enhances anti-cancer activity and ameliorates side effects in solid Ehrlich Carcinoma-bearing mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 105

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Compounding; Female; Fluorouracil; Mi

2018
Luteolin and 5-flurouracil act synergistically to induce cellular weapons in experimentally induced Solid Ehrlich Carcinoma: Realistic role of P53; a guardian fights in a cellular battle.
    Chemico-biological interactions, 2019, Sep-01, Volume: 310

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Caspase 3; Drug S

2019
Synthesis and anticancer evaluation of furfurylidene 4-piperidone analogs.
    Archiv der Pharmazie, 2014, Volume: 347, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Survival; Doxorubicin; Drug Design; F

2014
Apigenin potentiates the antitumor activity of 5-FU on solid Ehrlich carcinoma: Crosstalk between apoptotic and JNK-mediated autophagic cell death platforms.
    Toxicology and applied pharmacology, 2017, 02-01, Volume: 316

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apigenin;

2017
Antitumor activity of the immunomodulatory lead Cumaside.
    International immunopharmacology, 2010, Volume: 10, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cholesterol; Female; Flu

2010
Development and characterization of hyaluronic acid decorated PLGA nanoparticles for delivery of 5-fluorouracil.
    Drug delivery, 2010, Volume: 17, Issue:8

    Topics: Animals; Biocompatible Materials; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Chemistry, Pharmaceuti

2010
Antitumor and anticytopenic effects of aqueous extracts of propolis in combination with chemotherapeutic agents.
    Cancer biotherapy & radiopharmaceuticals, 2002, Volume: 17, Issue:5

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Proto

2002
Pretreatment growth environments alter the sensitivity of tumor cells to cytotoxic agents.
    Free radical biology & medicine, 2003, Aug-01, Volume: 35, Issue:3

    Topics: Agar; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antioxidants; Bleomycin; Carcinom

2003
Cytochemical effects of 5-fluorouracil on sensitive and resistant Ehrlich ascites tumor cells.
    Cancer research, 1959, Volume: 19, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Fluorouracil; Neoplasms; Nucleic Acids; Pr

1959
Antimitotic action of 5-(2'-bromo-acetamido)-uracil on the Ehrlich ascites tumor.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1962, Volume: 111

    Topics: Animals; Antimitotic Agents; Antineoplastic Agents; Carcinoma; Carcinoma, Ehrlich Tumor; Fluorouraci

1962
Studies on resistance against 5-fluorouracil. III. Selective value of resistant, uridine kinase-deficient tumor cells.
    Cancer research, 1962, Volume: 22

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Fluorouracil; Humans; Phosphotransferases; Uridine Kin

1962
INHIBITION OF EHRLICH ASCITES TUMOR WITH 5-FLUOROURACIL AND OTHER AGENTS.
    Experimental cell research, 1963, Volume: 24

    Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Ehrlich Tumor; Floxuridine; Fluorouracil; Hydr

1963
GROWTH INHIBITION OF A SPECTRUM OF TRANSPLANTED MOUSE TUMORS BY COMBINATIONS OF INHIBITORS OF NUCLEIC ACID BIOSYNTHESIS AND ALKYLATING AGENTS.
    Cancer research, 1963, Volume: 23

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor;

1963
IN VITRO TEST SYSTEMS FOR CANCER CHEMOTHERAPY. II. CORRELATION OF IN VITRO INHIBITION OF DEHYDROGENASE AND GROWTH WITH IN VIVO INHIBITION OF EHRLICH ASCITES TUMOR.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 114

    Topics: Animals; Antineoplastic Agents; Arsenicals; Carbamates; Carcinoma; Carcinoma, Ehrlich Tumor; Colchic

1963
UTILIZATION OF DNA AND RNA PRECURSORS AS INDICATORS OF DRUG EFFECT ON CANCER CELLS. ANL-6723.
    ANL, 1963

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Dactinomycin; DNA; DNA, Neoplasm; Fluorour

1963
EXPERIMENTAL CHEMOTHERAPY STUDIES. V. THE COLLATERAL SENSITIVITY TO ALKYLATING AGENTS OF SEVERAL ANTIMETABOLITE-RESISTANT ASCITES TUMORS IN MICE.
    Cancer research, 1964, Volume: 24

    Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Ascites; Azaserine; Carcinoma, E

1964
INTERACTION BETWEEN 5-HYDROXYTRYPTAMINE AND ANTITUMOURAL DRUGS.
    The Journal of pharmacy and pharmacology, 1964, Volume: 16

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Fluorouracil; Melphalan;

1964
FLUORINATED PYRIMIDINES. XXII. EFFECTS OF VARIOUS COMPOUNDS ON THE INCORPORATION OF (14C)FORMATE INTO DNA THYMINE IN SUSPENSIONS OF EHRLICH ASCITES CELLS.
    Biochimica et biophysica acta, 1964, Dec-16, Volume: 91

    Topics: Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; DNA;

1964
INFLUENCE OF PURINE AND PYRIMIDINE COMPOUNDS ON DNA-SYNTHESIS OF ASCITES-TUMOUR CELLS.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Animals; Ascites; Carcinoma, Ehrlich Tumor; Cytosine Nucleotides; DNA; DNA, Neoplasm; Fluorouracil;

1964
IN VITRO TEST SYSTEMS FOR CANCER CHEMOTHERAPY. 3. PRELIMINARY STUDIES OF SPONTANEOUS MAMMARY TUMORS IN MICE.
    Cancer chemotherapy reports, 1965, Volume: 44

    Topics: Alkylating Agents; Animals; Carcinoma, Ehrlich Tumor; Dactinomycin; Fluorouracil; Hydrocortisone; In

1965
Combined action of 5-fluorouracil and other cytotoxic agents with crystalline ribonuclease on mouse ascites tumor.
    Henry Ford Hospital medical bulletin, 1961, Volume: 9

    Topics: Animals; Antineoplastic Agents; Ascites; Carcinoma, Ehrlich Tumor; Cytotoxins; Fluorouracil; Mice; N

1961
Enhancement of antitumor effects of 5-fluorouracil combined with ultrasound on Ehrlich ascites tumor in vivo.
    Ultrasound in medicine & biology, 2003, Volume: 29, Issue:11

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Ehrlich Tumor; Combined Modality Therapy; Fluor

2003
Chloroquine treatment increases detection of 5-fluorouracil-induced apoptosis index in vivo.
    Molecular imaging, 2006, Volume: 5, Issue:3

    Topics: Animals; Apoptosis; Bone Marrow Cells; Carcinoma, Ehrlich Tumor; Chloroquine; Drug Synergism; Fluoro

2006
Antitumor activity of biflorin, an o-naphthoquinone isolated from Capraria biflora.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:8

    Topics: Adjuvants, Immunologic; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic;

2007
Transdermal delivery of 5-fluorouracil for induced ehrlich ascites carcinoma tumor in BALB/c mice and pharmacokinetic study.
    Recent patents on anti-cancer drug discovery, 2007, Volume: 2, Issue:3

    Topics: Adhesiveness; Administration, Cutaneous; Animals; Antimetabolites, Antineoplastic; Carcinoma, Ehrlic

2007
[Antiblastic effect of various chemotherapeutic preparations on the cells of the Ehrlich ascites tumor].
    Voprosy onkologii, 1966, Volume: 12, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Busulfan; Carcinoma, Ehrlich Tumor; Flu

1966
Analysis of the effect of 5-fluorouracil on the synthesis and translation of polysomal poly(A)RNA from Ehrlich ascites cells.
    Molecular pharmacology, 1981, Volume: 19, Issue:1

    Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; Fluorouracil; In Vitro Techniques; Poly A; Protein Bio

1981
Selective activation of 5'-deoxy-5-fluorouridine by tumor cells as a basis for an improved therapeutic index.
    Cancer research, 1981, Volume: 41, Issue:12 Pt 1

    Topics: Animals; Biotransformation; Bone Marrow; Carcinoma, Ehrlich Tumor; Cells, Cultured; Floxuridine; Flu

1981
Active transport of 5-fluorouracil and its energy coupling in Ehrlich ascites tumor cells.
    Journal of biochemistry, 1981, Volume: 90, Issue:3

    Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Chloromercu

1981
[Autoradiography studies of cell proliferation and the effect of cytostatic agents on the proliferation of normal and tumor cells].
    Acta histochemica. Supplementband, 1983, Volume: 27

    Topics: Animals; Antineoplastic Agents; Autoradiography; Bleomycin; Carcinoma, Ehrlich Tumor; Cell Cycle; Ce

1983
[Potentiation of cytotoxic effects of 5-fluorouracil by inosiplex on cancer cells].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Survival; Drug Synergism; Female; Fluorouraci

1984
Rate-limiting steps in the interactions of fluoropyrimidines and methotrexate.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:5

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactions;

1984
Metabolism and biological activity of 5'-deoxy-5-fluorouridine, a novel fluoropyrimidine.
    Cancer research, 1980, Volume: 40, Issue:9

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chromatography, Liquid; F

1980
Antitumor effect of 5-fluorouracil in combination with some additives which stimulate the formation of antineoplastic 5-fluorouracil nucleotides.
    Gan, 1983, Volume: 74, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Drug Therapy, Combination; Edetic Acid; Fluorour

1983
[Intraperitoneal administration of FT-207 for mouse peritonitis carcinomatosa].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:4

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Fluorouracil; Injections, Intraperitoneal; Macroph

1984
[Pharmacokinetics of fluoropyrimidines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Fluorouracil; Hum

1984
[Effect of adenosine triphosphate on the proliferation of cultured tumor cells].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1984, Volume: 104, Issue:11

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cells, Cultured; D

1984
Induction by 5-fluorouracil of a major phase difference in the circadian profiles of DNA synthesis between the Ehrlich ascites carcinoma and five normal organs.
    Cancer letters, 1983, Volume: 20, Issue:2

    Topics: Animals; Bone Marrow; Carcinoma, Ehrlich Tumor; Circadian Rhythm; DNA; Fluorouracil; Ileum; Male; Mi

1983
Host interactions in the effects of 5-fluorouracil on Ehrlich ascites tumor cells.
    Cancer research, 1982, Volume: 42, Issue:12

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Cycle; DNA Replication; DNA, Neoplasm; Female; Fluorescent A

1982
High-dose therapy with ftorafur in gastrointestinal cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1981, Volume: 79

    Topics: Animals; Carcinoma, Ehrlich Tumor; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplas

1981
Increased uptake of 5-fluorouracil by Ehrlich ascites tumor cells with some additives and metabolite analysis.
    Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:11

    Topics: Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane Permeability; Deoxyuridine;

1982
[Pre-operative chemotherapy of stomach cancer combined with local administration of OK-432--evaluation of macroscopic results].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:1

    Topics: Aged; Animals; Antibiotics, Antineoplastic; Biological Products; Carcinoma, Ehrlich Tumor; Drug Ther

1982
[Biochemical differences in the tumor cells of 5-fluorouracil-sensitive and -resistant strains of Ehrlich ascitic carcinoma].
    Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 95, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Drug Resistance; Fluorouracil; In Vitro Techniqu

1983
Apparent ineffectiveness of adriamycin for growth of androgen-dependent Shionogi carcinoma 115 in the mouse.
    Cancer letters, 1983, Volume: 17, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Doxorubicin; Drug Resistance; Fluoroura

1983
[adenylate cyclase system in Ehrlich ascites tumor cells sensitive and resistant to 5-fluorouracil].
    Ukrainskii biokhimicheskii zhurnal (1978), 1982, Volume: 54, Issue:1

    Topics: Adenylyl Cyclases; Animals; Carcinoma, Ehrlich Tumor; Drug Resistance; Fluorouracil; Mice

1982
[Effect of ascorbic acid on incorporation of 5-fluorouracil-6-3H into acid-soluble fraction and into RNA of sensitive and resistant to 5-fluorouracil cells of Ehrlich ascites carcinoma].
    Biulleten' eksperimental'noi biologii i meditsiny, 1982, Volume: 93, Issue:2

    Topics: Animals; Ascorbic Acid; Carcinoma, Ehrlich Tumor; Cell Fractionation; Cell Line; Drug Interactions;

1982
Improved measurement of thymidylate synthetase activity by a modified tritium-release assay.
    Journal of biochemical and biophysical methods, 1982, Volume: 6, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; Charcoal; Deoxyuracil Nucleotides; Fluorouracil; Methods; Methylt

1982
Additive formation of antineoplastic 5-fluorouracil nucleosides from 5-fluorouracil by Ehrlich ascites tumor extracts in the presence of ribose 1-phosphate/uridine or deoxyribose 1-phosphate/deoxyuridine.
    Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:9

    Topics: Animals; Ascites; Carcinoma, Ehrlich Tumor; Deoxyuridine; Fluorouracil; In Vitro Techniques; Liver;

1982
Antitumor effect of ethylene-vinyl acetate copolymer matrices containing 5-fluorouracil on Ehrlich ascites carcinoma in mice.
    Chemical & pharmaceutical bulletin, 1982, Volume: 30, Issue:10

    Topics: Animals; Carcinoma, Ehrlich Tumor; Delayed-Action Preparations; Fluorouracil; Kinetics; Mice; Mice,

1982
Search for the biochemical parameters of tumor cell sensitivity and resistance to antimetabolites.
    Antibiotics and chemotherapy, 1980, Volume: 28

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Ehrlich Tumor; Cell Line; Drug Resistance; Fluo

1980
5-fluorouracil uptake by irradiation perturbed tumor.
    Oncology, 1981, Volume: 38, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Fluorouracil; Mice; Mice, Inbred C57BL; Time Facto

1981
Antitumor activity of 1-alkoxycarbonylalkylcarbamoyl-5-fluorouracil derivatives by oral administration.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Fema

1981
Increased formation of 5-fluoro-2'-deoxyuridine 5'-monophosphate from 5-fluorouracil in the presence of 2-deoxy-alpha-D-ribose 1-phosphate and 2'-deoxyuridine in Ehrlich ascites tumor cells.
    Nucleic acids symposium series, 1980, Issue:8

    Topics: Animals; Carcinoma, Ehrlich Tumor; Deoxyuracil Nucleotides; Deoxyuridine; Fluorodeoxyuridylate; Fluo

1980
Effect of liposome-entrapped 5-fluorouracil on Ehrlich ascites tumour bearing mice.
    Indian journal of biochemistry & biophysics, 1981, Volume: 18, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Survival; Fluorouracil; Kinetics; Liposomes; Male; Mice

1981
[Mechanism of the antitumor action of 5-fluorouracil].
    Doklady Akademii nauk SSSR, 1980, Volume: 253, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Fluorouracil; Liver Neoplasms, Experimental; Male;

1980
[Effect of dan-shen and anticancer drugs on the cancer cell surface agglutination induced by phytoagglutinin (author's transl)].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1980, Volume: 2, Issue:1

    Topics: Agglutination; Animals; Antineoplastic Agents; Asparaginase; Carcinoma, Ehrlich Tumor; China; Fluoro

1980
Drug-carrier property of albumin microspheres in chemotherapy. IV. Antitumor effect of single-shot or multiple-shot administration of microsphere-entrapped 5-fluorouracil on Ehrlich ascites or solid tumor in mice.
    Chemical & pharmaceutical bulletin, 1980, Volume: 28, Issue:10

    Topics: Animals; Carcinoma, Ehrlich Tumor; Fluorouracil; Male; Mice; Microspheres; Neoplasms, Experimental;

1980
Antibiotic C3368-A, a fungus-derived nucleoside transport inhibitor, potentiates the activity of antitumor drugs.
    Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzofurans; Biological Transport; Carc

1995
Tea plant root extract (TRE) as an antineoplastic agent.
    Planta medica, 1994, Volume: 60, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Fluorouracil; Male; Mice; Mice

1994
Stimulation of tumor-cell growth by alpha-fetoprotein.
    International journal of cancer, 1998, Feb-09, Volume: 75, Issue:4

    Topics: alpha-Fetoproteins; Animals; Ascites; Carcinoma, Ehrlich Tumor; Cell Division; Female; Fluorouracil;

1998
Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells.
    British journal of cancer, 1998, Volume: 77, Issue:6

    Topics: Adenocarcinoma; Animals; Biological Transport; Carbon Radioisotopes; Carbonyl Cyanide p-Trifluoromet

1998
[Antineoplastic activity of 5-fluorouracil upon transdermal adminstration using "Coletex" napkins].
    Voprosy onkologii, 2001, Volume: 47, Issue:4

    Topics: Administration, Cutaneous; Animals; Antimetabolites, Antineoplastic; Carcinoma, Ehrlich Tumor; Femal

2001
Plasma, intestine and tumor levels of 5-fluorouracil in mice bearing L1210 ascites tumor following oral administration of 5-fluorouracil, UFT (mixed compound of tegafur and uracil), carmofur and 5'-deoxy-5-fluorouridine.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Combinations; F

2001
Cell synchronization in solid tumors.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1975, Issue:52

    Topics: Animals; Bleomycin; Carcinoma, Ehrlich Tumor; Cell Division; Cricetinae; DNA, Neoplasm; Fluorouracil

1975
Dextran derivatives in single and combination chemotherapy against transplantable mouse ascites and solid tumors.
    Cancer research, 1977, Volume: 37, Issue:9

    Topics: Animals; Antibody Formation; Antineoplastic Agents; Bleomycin; Carcinoma, Ehrlich Tumor; Cells, Cult

1977
[Uridine kinase, its structure, properties and biological function].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1978, Issue:4

    Topics: Animals; Azacitidine; Brain; Carcinoma, Ehrlich Tumor; Chick Embryo; Drug Resistance; Fluorouracil;

1978
Effect of irradiation and chemotherapeutic agents on the capillaries of Ehrlich ascites carcinoma of mice.
    Acta radiologica: oncology, radiation, physics, biology, 1979, Volume: 18, Issue:6

    Topics: Animals; Bleomycin; Capillaries; Carcinoma, Ehrlich Tumor; Cobalt Radioisotopes; Female; Fluorouraci

1979
[The correlation of in vivo and in vitro effect of cytostatics in transplantated tumours of the mouse (author's transl)].
    Acta histochemica, 1978, Volume: 62, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Dihydrolipoamide Dehydrogenase; Fluorourac

1978
Distinguishing between membrane transport and intracellular metabolism of fluorodeoxyuridine in Ehrlich ascites tumor cells by application of kinetic and high performance liquid chromatographic techniques.
    The Journal of biological chemistry, 1979, Jun-25, Volume: 254, Issue:12

    Topics: Animals; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cell Membrane; Chromatography, High

1979
Distribution of 18F-5-fluorouracil in tumor-bearing mice and rats.
    International journal of nuclear medicine and biology, 1978, Volume: 5, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Fluo

1978
Anti-tumor activities of 1-Acetyl-3-o-Toluyl-5-Fu.
    Hiroshima journal of medical sciences, 1979, Volume: 28, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Female; Fluorouracil; HeLa Cells; Leiomyosarcoma;

1979
Tumor uptake of radiolabeled pyrimidine bases and pyrimidine nucleosides in animal models--I. 6-[3H]-5-fluorouracil.
    International journal of nuclear medicine and biology, 1979, Volume: 6, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; Fluorouracil; Half-Life; Lung Neoplasms; Male; Mice; Models, Biol

1979
A basis for fluoropyrimidine-induced antagonism to methotrexate in Ehrlich ascites tumor cells in vitro.
    Cancer research, 1978, Volume: 38, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA, Neoplasm; Drug Therapy, Combination; Fluoroura

1978
Antitumor activity of 1-alkylcarbamoyl derivatives of 5-fluorouracil in a variety of mouse tumors.
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Fluorouracil; Leukemia, Ex

1978
Combined treatment with anaerobic Corynebacterium liquefaciens and chemotherapeutics against solid tumor in mice.
    Gan, 1977, Volume: 68, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Female; Fluorouracil; Immunotherapy; Injections

1977
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil in a variety of experimental tumors.
    Gan, 1976, Volume: 67, Issue:5

    Topics: Adenocarcinoma; Administration, Oral; Animals; Ascites; Carcinoma, Ehrlich Tumor; Female; Fluorourac

1976
Combination of non-specific immunopotentiation with Corynebacterium liquefaciens and chemotherapy in tumor-bearing mice.
    Gan, 1975, Volume: 66, Issue:6

    Topics: Animals; Antineoplastic Agents; Bacterial Vaccines; Carcinoma, Ehrlich Tumor; Corynebacterium; Cyclo

1975
[Radiotherapy combined with halogenated pyrimidines--fundamental and clinical studies (author's transl)].
    Nihon Gan Chiryo Gakkai shi, 1975, Sep-20, Volume: 10, Issue:3

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Female; Fluorouracil; Halogens; Head and Neck Neoplasm

1975
Effect of N1-(2'-tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil on nucleic acid and protein biosyntheses in Ehrlich ascites cells.
    Cancer research, 1976, Volume: 36, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; DNA, Neoplasm; Fluorouracil; Furans; Liver; Male

1976
Kinetic alterations induced by 5-fluorouracil in bone marrow, intestinal mucosa, and tumor.
    Cancer research, 1976, Volume: 36, Issue:5

    Topics: Animals; Bone Marrow; Carcinoma, Ehrlich Tumor; Cell Division; Deoxyuridine; DNA; DNA, Neoplasm; Dos

1976
Experimental study on the effect of large-dose intratumoral OK-432 administration in mice.
    Gan, 1976, Volume: 67, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Ehrlich Tumor; Cytarabine; Drug Therapy, Combinatio

1976
[Pharmacokinetic studies on fluorinated pyrimidine in cancer cell and tissue].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:4

    Topics: Animals; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Esophageal Neoplasms; Female; Fluorouracil; Gl

1992
Detection of differential sensitivity to 5-fluorouracil in Ehrlich ascites tumour cells by 19F NMR spectroscopy.
    NMR in biomedicine, 1991, Volume: 4, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Extracts; Chr

1991
The role of glutathione in evaluating the efficacy of antimetabolites in transplanted tumors.
    Neoplasma, 1991, Volume: 38, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Count; Female; Floxuridine; Fluorouracil; Glutathione; Liver

1991
Competitive binding radioassay for the determination of 5-fluorodeoxyuridine and 5-fluorodeoxyuridine-5'-monophosphate levels in plasma and tumor tissue.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:6

    Topics: Animals; Carcinoma, Ehrlich Tumor; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Kinetics; Lactic

1991
Efficacy of 5-fluorouracil in combination with methoxyphenyl maleamic acid in murine tumors.
    Journal of postgraduate medicine, 1991, Volume: 37, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Drug Therapy, Com

1991
Influence of N-(o-methoxyphenyl)-maleimide on 5-fluorouracil cytotoxicity in Ehrlich (ascites) carcinoma.
    Cancer letters, 1991, Volume: 57, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich T

1991
[Studies of 5-fluorouracil nanocapsules].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1991, Volume: 26, Issue:4

    Topics: Animals; Capsules; Carcinoma, Ehrlich Tumor; Drug Carriers; Enbucrilate; Female; Fluorouracil; Liver

1991
Cell death in relation to cell cycle in a mouse ascites tumor growing in vivo after combined treatment with cisplatin and 5-fluorouracil.
    Anti-cancer drugs, 1990, Volume: 1, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell

1990
Modulating effect of alpha-[N,N-[bis(2-hydroxyethyl)]-amino-N- (o-methoxyphenyl)-pyrrolidin-2,5-dione on the chemotherapy of murine tumours.
    Cancer letters, 1990, May-30, Volume: 51, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Drug Synergism; F

1990
Binucleate cells in the Ehrlich ascites tumor. Autoradiographic labeling.
    Biology of the cell, 1989, Volume: 65, Issue:1

    Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Nucleus; Female; Fluorouracil; Mice; Mice,

1989
Effect of antineoplastic drugs and estradiol on leucine uptake and proliferation of Ehrlich tumor cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1989, Volume: 43, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Division; Doxorubicin; Estradiol; Flu

1989
Effect of implanted ethylene-vinyl alcohol copolymer matrices containing 5-fluorouracil on Ehrlich ascites carcinoma.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Drug Implants; Fluorouracil; Male; Mice; Mice, Inbred Strains; Po

1985
[5'-DFUR (doxifluridine)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:7

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Evaluation; Floxuridine; Fluorouracil

1987
Binucleate cells in the Ehrlich ascites tumor. Action of 5-fluorouracil.
    Biology of the cell, 1987, Volume: 60, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Nucleus; Dose-Response Relationship, Drug; Female; Fluoroura

1987
[Synchronization of tumor cells with 5-fluorouracil plus uracil and with vinblastine and irradiation of the synchronized cultures. A contribution to combined radio-chemotherapy].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1988, Volume: 164, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Combined Modality Therapy; Fluorouracil; In Vitro

1988
Enhancement of antitumor effects of 1-hexylcarbamoyl-5-fluorouracil combined with hyperthermia on Ehrlich ascites tumor in vivo and Nakahara-Fukuoka sarcoma cell in vitro.
    Cancer research, 1988, Jul-15, Volume: 48, Issue:14

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Survival; Combined Modality Therapy; Fluorouracil

1988
[Clinical and experimental studies of shengxue tang combined with chemotherapy in the treatment of late-stage gastric cancer].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1987, Volume: 7, Issue:12

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Drug

1987
Mechanisms of potentiation of antitumor activity of 5-fluorouracil by ribothymidine in a mouse tumor system.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:12

    Topics: Animals; Carcinoma, Ehrlich Tumor; Drug Synergism; Fluorouracil; In Vitro Techniques; Liver; Male; M

1986
[Dilution of the toxic action of 5-fluorouracil on the mucosa of the small intestine in mice using the sap of plantain].
    Voprosy onkologii, 1987, Volume: 33, Issue:7

    Topics: Animals; Carcinoma, Ehrlich Tumor; Drug Evaluation, Preclinical; Drug Interactions; Fluorouracil; In

1987
Urinary polyamine excretion by tumor-bearing and tumor-free mice exposed to cyclophosphamide, 5-fluorouracil and 6-mercaptopurine.
    Journal of cancer research and clinical oncology, 1986, Volume: 111, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; Creatinine; Cyclophosphamide; Female; Fluorouracil; Mercaptopurin

1986
[Experimental studies on the uptake of anticancer drugs in cancer cells in hyperthermochemotherapy--effects of in vitro and in vivo heating on the uptake of 5-fluorouracil in Ehrlich cells].
    Nihon Geka Gakkai zasshi, 1986, Volume: 87, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Combined Modality Therapy; Fluorouracil; Hot Tem

1986
Intratumoral injection of thymidine: enhancement of the antitumor activity and incorporation of 5-fluorouracil into tumor RNA in a murine tumor system.
    Cancer treatment reports, 1986, Volume: 70, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Dose-Response Rel

1986
Fibrinogen microspheres as novel drug delivery systems for antitumor drugs.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Fibrinogen; Fluorouracil; Male; Mice; Micr

1986
Enhancement of antitumor activity of 5-fluorouracil by ribothymidine.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Drug Synergism; F

1986
Dihydrofluorouracil, a fluorouracil catabolite with antitumor activity in murine and human cells.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Animals; Antineoplastic Agents; beta-Alanine; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Cell Line;

1985
Inhibition of DNA polymerases and neoplastic cells by selected SH inhibitors.
    Oncology, 1972, Volume: 26, Issue:6

    Topics: Animals; Antineoplastic Agents; Arsenicals; Benzoates; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Ch

1972
Increase in RNase and DPNase activities in ascites tumor cells induced by various cytostatic agents.
    Biochemical and biophysical research communications, 1966, May-25, Volume: 23, Issue:4

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Nucleolus; Cell Nucleus; Colchicine; Dactinom

1966
[Effect of antineoplastic agents on the activity and molecular heterogeneity of lysosomal hydrolases in Ehrlich ascites tumor].
    Doklady Akademii nauk SSSR, 1974, Aug-01, Volume: 217, Issue:4

    Topics: Acid Phosphatase; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Chromatography, DEAE-Cel

1974
[In vitro effect of antitumor preparations on the hydrolase activity of lysosomes of tumor cells].
    Voprosy onkologii, 1974, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Fluorouracil; Humans; Hydrolases; In Vitro

1974
[Comparative in vitro studies with 5-fluorouracil and some of its derivatives].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1969, Volume: 350, Issue:6

    Topics: Acyltransferases; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell-Free System; Depression,

1969
Enhancement of the antitumor activity of 5-fluorouracil by drug combinations.
    Cancer research, 1973, Volume: 33, Issue:5

    Topics: Animals; Body Weight; Carcinoma, Ehrlich Tumor; Cell Count; Floxuridine; Fluorouracil; Hydroxyurea;

1973
The nucleotides of fluorinated pyrimidines and their biological activities.
    Ciba Foundation symposium, 1971, Volume: 2

    Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chromatography, Ion Exchange; F

1971
Buoyant density gradient centrifugation of RNA and DNA in alkali iodide solutions.
    Biochimica et biophysica acta, 1971, Nov-19, Volume: 247, Issue:4

    Topics: Animals; Carcinoma, Ehrlich Tumor; Centrifugation, Density Gradient; Clostridium perfringens; Cytosi

1971
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
    Oncology, 1974, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radi

1974
A new approach to the development of anti-cancer agents-5-FU derivatives.
    Hiroshima journal of medical sciences, 1974, Volume: 23, Issue:2-3

    Topics: Animals; Candida albicans; Carcinoma, Ehrlich Tumor; Cells, Cultured; Fatty Acids; Female; Fluoroura

1974
[Experimental anc clinical studies on the sensitivity test for carcinostatic agent from the cytological point of view].
    Bulletin of the Chest Disease Research Institute, Kyoto University, 1972, Volume: 5, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cells, Cultur

1972
[Radiosensitizing chemical agents. Radiobiological reasons and prospects for their use].
    Minerva medica, 1972, Volume: 63, Issue:7

    Topics: Acetates; Animals; Bromodeoxyuridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Membrane; Cosmic R

1972
[Mechanism of action of ftorafur, a new antineoplastic agent].
    Voprosy meditsinskoi khimii, 1972, Volume: 18, Issue:3

    Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Carbon Radioisotopes; Carcinoma, Ehrlich Tumo

1972
Nucleolar alterations in ascites tumour cells induced by 5-fluorouracil treatment.
    Neoplasma, 1973, Volume: 20, Issue:3

    Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Nucleolus; DNA; Fluorouracil; Mice; Microsc

1973
Antileukemic properties of dichloro(1,2-diaminocyclohexane)platinum(II).
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cisplatin; Cyclophosphamide; DNA, Neoplasm; Drug

1974
[On selection of antineoplastic agents for local use].
    Voprosy onkologii, 1969, Volume: 15, Issue:7

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Female; Fluorouracil; In Vitro Techniques;

1969
Observations with a variant of lymphocytic choriomeningitis virus in mouse tumors.
    Cancer research, 1970, Volume: 30, Issue:7

    Topics: Animals; Antigens; Carcinoma, Ehrlich Tumor; Female; Fluorouracil; Immunotherapy; Lymphocytic Chorio

1970
Unequal inhibition of RNA synthesis in mitochondria and whole cells of Ehrlich ascites tumour treated with 5-fluorouracil.
    Neoplasma, 1972, Volume: 19, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Fluorouracil; Mice; Mitochondria; Organelle Biogenesis; RNA, Neop

1972
Resistance of amino acid incorporation by mitochondria isolated from Ehrlich ascites tumour cells to the in vivo treatment with 5-fluorouracil.
    Neoplasma, 1972, Volume: 19, Issue:1

    Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Fluorouracil; In Vitro Techniqu

1972
Hydron: an implantable device for the delivery of antitumor chemotherapy.
    Archives of surgery (Chicago, Ill. : 1960), 1972, Volume: 105, Issue:1

    Topics: Absorption; Acrylic Resins; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Fluorouracil;

1972
Fluorinated pyrimidines. XL. The reduction of 5-fluorouridine 5'-diphosphate by ribonucleotide reductase.
    Molecular pharmacology, 1972, Volume: 8, Issue:4

    Topics: Alcohol Oxidoreductases; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cells, Cultured; Chromatograp

1972
Antitumor activity of cyclocytidine in a variety of tumors.
    Gan, 1972, Volume: 63, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Cyclization; Cy

1972
[Experimental studies on antineoplastic action of N 1 -(2'-tetrahydrofuryl)-5-fluorouracil (FT-207)--effect on experimental tumors].
    Gan no rinsho. Japan journal of cancer clinics, 1971, Volume: 17, Issue:10

    Topics: Animals; Body Weight; Carcinoma, Ehrlich Tumor; Fluorouracil; Furans; Mice; Neoplasms, Experimental;

1971
A further correlation between the response of lysogenic bacteria and tumor cells to chemical agents.
    Proceedings of the National Academy of Sciences of the United States of America, 1966, Volume: 55, Issue:2

    Topics: Animals; Bacterial Proteins; Carcinoma, Ehrlich Tumor; Chelating Agents; Chloramphenicol; DNA, Bacte

1966
A new paper chromatography solvent system resolving pyrimidine-pyrimidine riboside-pyrimidine deoxyriboside mixtures.
    Analytical biochemistry, 1969, Volume: 30, Issue:3

    Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Chromatography, Paper; Culture Techniques; C

1969
[Effects of "cell membrane-acting" substances on uptake of anticancer chemotherapeutics by tumor cells--with special reference to mitomycin C uptake by Ehrlich ascites tumor cells in vitro--].
    Sapporo igaku zasshi. The Sapporo medical journal, 1969, Volume: 35, Issue:4

    Topics: Animals; Antifungal Agents; Carcinoma, Ehrlich Tumor; Cell Membrane Permeability; DNA, Neoplasm; Flu

1969
Preferential attack on cancer by selected SH inhibitors.
    JAMA, 1970, Oct-05, Volume: 214, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Ascites; Breast Neoplasms; Carcinoma, Ehrlich Tumor;

1970
The place of 5-fluorouracil in experimental and clinical cancer chemotherapy.
    Dermatologica, 1970, Volume: 140

    Topics: Animals; Carcinoma, Ehrlich Tumor; Fluorouracil; Humans; Mice; Neoplasms; Sarcoma 180

1970
[Chemotherapy of murine Ehrlich carcinoma and rat Yoshida sarcoma transplanted on hamsters].
    Bratislavske lekarske listy, 1970, Volume: 54, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cricetinae; Cyclophosphamide; Fluorouracil

1970
Adverse effect of antitumor drugs on the prevention of metastasis in mice.
    Chemical & pharmaceutical bulletin, 1970, Volume: 18, Issue:11

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Fluorouracil; Male; Merc

1970
Potential anticancer agents. VI. 5-Substituted pyrimidine-6-carboxaldehydes.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:11

    Topics: Aldehydes; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chemical Pheno

1970
[On uptake of 5-FU, 6-MP and methotrexate by ehrlich ascites tumor cells in vitro].
    Sapporo igaku zasshi. The Sapporo medical journal, 1970, Volume: 37, Issue:6

    Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Fluorouracil; In Vitro Techniques; Male;

1970
[Indication for antineoplastic agents and administration methods].
    Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Fluorouracil; Mice; Tetr

1971
[On the biochemical causes of the cytostatic effect of glyceraldehyde].
    Acta biologica et medica Germanica, 1967, Volume: 19, Issue:1

    Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell

1967
Fluorinated pyrimidine aldehydes. Inhibition of nucleic acid and protein biosynthesis in Ehrlich ascites carcinoma cells in vitro.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:3

    Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; Chromatography, Th

1968
[Combined therapy of lung carcinoma with 5-fluorouracil and 60Co irradiation].
    Gan no rinsho. Japan journal of cancer clinics, 1968, Volume: 14, Issue:5

    Topics: Adult; Aged; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Squamous Cell; Cobalt Isotopes; Female; F

1968
[5'-desoxy-5'-fluorothymidine, a new inhibitor of the DNA synthesis].
    Acta biologica et medica Germanica, 1968, Volume: 20, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Colorimetry; Depression, Chemical; DNA, Neoplasm; Fluorouracil; M

1968
Antiglycolytic activities of 5-fluorouracil and related pyrimidines in mouse ascites carcinoma cells with special reference to inorganic phosphate and glucose.
    Oncology, 1969, Volume: 23, Issue:1

    Topics: Adenine; Animals; Arsenic; Carcinoma, Ehrlich Tumor; Carcinoma, Krebs 2; Deoxyuridine; Fluorouracil;

1969
Stimulatory effects of inosine and deoxyinosine on the incorporation of uracil-2-14-C, 5-fluorouracil-2-14-C, and 5-bromouracil-2-14-C into nucleic acids by Ehrlich ascites tumor cells in vitro.
    Cancer research, 1969, Volume: 29, Issue:4

    Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Enzyme Precursors; Fluorouracil;

1969
Mechanism of growth inhibition by 5-fluorouracil. Reversal studies with pyrimidine metabolites in vitro.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 131, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Culture Techniques; Depression, Chemical; DNA, Neoplasm; Fluorour

1969
[Studies on the cell division inhibitory effect of some purine and pyrimidine derivatives on Paracentrotus lividus and on sarcoma 180 of mice].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:8

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Division; Culture Techniques; Echinod

1969
Comparative effects of DL-glyceraldehyde, 6-mercaptopurine, methotrexate and 5-fluorouracil on the Ehrlich ascites carcinoma in vivo.
    International journal of cancer, 1966, May-15, Volume: 1, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Drug Synergism; Female; Fluorouracil; Glyceraldehyde; Mercaptopur

1966