fluorouracil has been researched along with Carcinoma, Basosquamous in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Carcinoma, Basosquamous: A skin carcinoma that histologically exhibits both basal and squamous elements. (From Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relation between the induction of delayed hypersensitivity reactions to 5-FU following treatment with topical 5-FU and the cure rate for cutaneous neoplasms showed a trend toward correlation." | 5.25 | Delayed hypersensitivity to 5-fluorouracil following topical chemotherapy of cutaneous cancers. ( Ichinose, H; Krementz, ET; Litwin, MS; Mansell, PW, 1975) |
| "The basaloid squamous cell carcinoma of the esophagus is highly malignant with poor prognosis." | 1.35 | [Diagnosis and treatment of basaloid squamous cell carcinoma of the esophagus]. ( Chen, JX; Tang, Q; Zheng, YD; Zhu, HN, 2008) |
| "The relation between the induction of delayed hypersensitivity reactions to 5-FU following treatment with topical 5-FU and the cure rate for cutaneous neoplasms showed a trend toward correlation." | 1.25 | Delayed hypersensitivity to 5-fluorouracil following topical chemotherapy of cutaneous cancers. ( Ichinose, H; Krementz, ET; Litwin, MS; Mansell, PW, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JX | 1 |
| Tang, Q | 1 |
| Zhu, HN | 1 |
| Zheng, YD | 1 |
| Chetty, R | 1 |
| Serra, S | 1 |
| Hsieh, E | 1 |
| Mansell, PW | 1 |
| Litwin, MS | 4 |
| Ichinose, H | 2 |
| Krementz, ET | 3 |
| Ryan, RF | 2 |
| Reed, RR | 1 |
| Kremetz, ET | 1 |
| Ebner, H | 1 |
| Reed, RJ | 1 |
1 trial available for fluorouracil and Carcinoma, Basosquamous
| Article | Year |
|---|---|
Treatment of skin epitheliomas with 5-fluorouracil (5-FU) ointment. Influence of therapeutic design on recurrence of lesions.
Topics: Aged; Carcinoma, Basal Cell; Carcinoma, Basosquamous; Carcinoma, Squamous Cell; Clinical Trials as T | 1970 |
6 other studies available for fluorouracil and Carcinoma, Basosquamous
| Article | Year |
|---|---|
[Diagnosis and treatment of basaloid squamous cell carcinoma of the esophagus].
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Basosquamous; Carcinoma, Squamous Cell; Cisplatin; Co | 2008 |
Basaloid squamous carcinoma of the anal canal with an adenoid cystic pattern: histologic and immunohistochemical reappraisal of an unusual variant.
Topics: Anal Canal; Antibiotics, Antineoplastic; Antigens, CD20; Antimetabolites, Antineoplastic; Antineopla | 2005 |
Delayed hypersensitivity to 5-fluorouracil following topical chemotherapy of cutaneous cancers.
Topics: Administration, Topical; Biopsy; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Basosquamous; | 1975 |
Topical chemotherapy of basal and squamous skin cancers with 5-fluorouracil cream.
Topics: Administration, Topical; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Basosquamous; Carcinom | 1974 |
Proceedings: Use of 5 fluorouracil in the topical therapy of skin cancer: a review of 157 patients.
Topics: Administration, Topical; Adult; Aged; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Basosquam | 1972 |
Topical chemotherapy of advanced cutaneous malignancy with 5-Fluorouracil creme.
Topics: Aged; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Basosquamous; Carcinoma, Squamous Cell; Esthetics | 1971 |