fluorouracil has been researched along with Carcinoma, Acinar Cell in 16 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Carcinoma, Acinar Cell: A malignant tumor arising from secreting cells of a racemose gland, particularly the salivary glands. Racemose (Latin racemosus, full of clusters) refers, as does acinar (Latin acinus, grape), to small saclike dilatations in various glands. Acinar cell carcinomas are usually well differentiated and account for about 13% of the cancers arising in the parotid gland. Lymph node metastasis occurs in about 16% of cases. Local recurrences and distant metastases many years after treatment are common. This tumor appears in all age groups and is most common in women. (Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1240; from DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pancreatic acinar cell carcinoma is rare; it accounts for 1% of all malignant pancreatic exocrine tumors." | 1.72 | Successful conversion surgery after FOLFIRINOX therapy in a patient with advanced pancreatic acinar cell carcinoma with a solitary peritoneal dissemination: A case report. ( Hanazaki, K; Iguchi, M; Kitagawa, H; Kohsaki, T; Maeda, H; Munekage, M; Namikawa, T; Tanioka, N; Uchida, K; Uemura, S; Yamaguchi, S; Yamamoto, S, 2022) |
| "Pancreatic panniculitis is characterized by subcutaneous fat necrosis and is a rare presentation of an underlying pancreatic disease, appearing in approximately 2-3% of all patients with a pancreatic disease." | 1.72 | Painful lower limb nodules as first symptom of resectable pancreatic acinar cell cancer: a case report. ( Besselink, MG; Busch, OR; Haenen, SM; Post, HC; Roshani, S; Sarasqueta, AF; Tol, JAMG; van der Linden, MMD; van Steen, SCJ; Wilmink, JW; Wolkerstorfer, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Uemura, S | 1 |
| Maeda, H | 1 |
| Tanioka, N | 1 |
| Yamaguchi, S | 1 |
| Munekage, M | 1 |
| Kitagawa, H | 1 |
| Namikawa, T | 1 |
| Yamamoto, S | 1 |
| Kohsaki, T | 1 |
| Iguchi, M | 1 |
| Uchida, K | 1 |
| Hanazaki, K | 1 |
| Haenen, SM | 1 |
| Tol, JAMG | 1 |
| van Steen, SCJ | 1 |
| Busch, OR | 1 |
| Sarasqueta, AF | 1 |
| Roshani, S | 1 |
| Wolkerstorfer, A | 1 |
| van der Linden, MMD | 1 |
| Wilmink, JW | 1 |
| Post, HC | 1 |
| Besselink, MG | 1 |
| Busch, E | 1 |
| Werft, W | 1 |
| Bougatf, N | 1 |
| Hackert, T | 1 |
| Jäger, D | 1 |
| Springfeld, C | 1 |
| Berger, AK | 1 |
| Li, M | 1 |
| Mou, Y | 1 |
| Hou, S | 1 |
| Cao, D | 1 |
| Li, A | 1 |
| Schempf, U | 1 |
| Sipos, B | 1 |
| König, C | 1 |
| Malek, NP | 1 |
| Bitzer, M | 1 |
| Plentz, RR | 1 |
| Kruger, S | 1 |
| Haas, M | 1 |
| Burger, PJ | 1 |
| Ormanns, S | 1 |
| Modest, DP | 1 |
| Westphalen, CB | 1 |
| Kleespies, A | 1 |
| Angele, MK | 1 |
| Hartwig, W | 1 |
| Bruns, CJ | 1 |
| Kirchner, T | 1 |
| Werner, J | 1 |
| Heinemann, V | 1 |
| Boeck, S | 1 |
| Sugimoto, M | 1 |
| Hines, OJ | 1 |
| Dawson, DW | 1 |
| Muthusamy, VR | 1 |
| Reber, HA | 1 |
| Donahue, TR | 1 |
| Distler, M | 1 |
| Rückert, F | 1 |
| Dittert, DD | 1 |
| Stroszczynski, C | 1 |
| Dobrowolski, F | 1 |
| Kersting, S | 1 |
| Grützmann, R | 1 |
| Sorscher, SM | 1 |
| Simon, M | 1 |
| Bioulac-Sage, P | 1 |
| Trillaud, H | 1 |
| Blanc, JF | 1 |
| Lee, JL | 1 |
| Kim, TW | 1 |
| Chang, HM | 1 |
| Lee, SK | 1 |
| Kim, MH | 1 |
| Kang, YK | 1 |
| Kim, JS | 1 |
| Kim, JH | 1 |
| Mori, S | 1 |
| Kondoh, S | 1 |
| Ryozawa, S | 1 |
| Urayama, N | 1 |
| Satake, M | 1 |
| Kitoh, H | 1 |
| Yamashita, H | 1 |
| Nakashima, T | 1 |
| Gondo, T | 1 |
| Okita, K | 1 |
| Sakon, M | 1 |
| Osato, H | 1 |
| Kishimoto, S | 1 |
| Aoki, T | 1 |
| Yamada, T | 1 |
| Higaki, N | 1 |
| Taniguchi, K | 1 |
| Sugimoto, K | 1 |
| Dohno, K | 1 |
| Umeshita, K | 1 |
| Gotoh, M | 1 |
| Monden, M | 2 |
| Shimoike, T | 1 |
| Goto, M | 1 |
| Nakano, I | 1 |
| Sato, T | 1 |
| Migita, Y | 1 |
| Ito, T | 1 |
| Yanase, T | 1 |
| Sezai, S | 1 |
| Suzuki, T | 1 |
| Nawata, H | 1 |
| Rink, T | 1 |
| Schröder, O | 1 |
| Dietrich, C | 1 |
| Kirchner, J | 1 |
| Hör, G | 1 |
| Zeuzem, S | 1 |
| Baum, RP | 1 |
| Ukei, T | 1 |
| Okagawa, K | 1 |
| Uemura, Y | 1 |
| Miyauchi, K | 1 |
| Kaneko, T | 1 |
| Mizunoya, S | 1 |
3 reviews available for fluorouracil and Carcinoma, Acinar Cell
| Article | Year |
|---|---|
Metastatic Acinar Cell Carcinoma of the Pancreas: A Retrospective Cohort Study on Systemic Chemotherapy and Review of the Literature.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Acinar Cell; Deoxycytidine; | 2021 |
FOLFOX regimen in pancreatic acinar cell carcinoma: case report and review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Acinar Cell; Fluorouracil; Humans; | 2012 |
[A case of AFP producing pancreatic acinar cell carcinoma diagnosed by EUS FNA and treated by intraarterial injection chemotherapy].
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Fine-Needle; Carc | 2004 |
13 other studies available for fluorouracil and Carcinoma, Acinar Cell
| Article | Year |
|---|---|
Successful conversion surgery after FOLFIRINOX therapy in a patient with advanced pancreatic acinar cell carcinoma with a solitary peritoneal dissemination: A case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Acinar Cell; Fluorouracil; Humans; | 2022 |
Painful lower limb nodules as first symptom of resectable pancreatic acinar cell cancer: a case report.
Topics: Acinar Cells; Aged; Carcinoma, Acinar Cell; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Li | 2022 |
Response of germline BRCA2-mutated advanced pancreatic acinar cell carcinoma to olaparib: A case report.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; BRCA2 Protein; | 2018 |
FOLFIRINOX as first-line treatment for unresectable acinar cell carcinoma of the pancreas: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Acinar Cell; Fluorouracil; | 2014 |
Acinar cell carcinoma of the pancreas: a rare disease with different diagnostic and therapeutic implications than ductal adenocarcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Acinar Cell; Carcinoma, Pan | 2016 |
Preoperative Treatment With FOLFIRINOX and Successful Resection for a Patient With Mixed Acinar-Endocrine Carcinoma of the Pancreas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Acinar Cell; Carcinoma, Isl | 2017 |
Curative resection of a primarily unresectable acinar cell carcinoma of the pancreas after chemotherapy.
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Acinar Cell; Combined Modality Therapy; Fluorourac | 2009 |
Metastatic acinar cell carcinoma of the pancreas responding to gemcitabine, 5-fluorouracil and leucovorin therapy: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Acinar Cell; Deoxycytidine; Drug Resistan | 2009 |
Locally advanced acinar cell carcinoma of the pancreas successfully treated by capecitabine and concurrent radiotherapy: report of two cases.
Topics: Adult; Capecitabine; Carcinoma, Acinar Cell; Deoxycytidine; Female; Fluorouracil; Humans; Male; Midd | 2003 |
[A patient with pancreatic acinar cell carcinoma, effectively treated by the infusion chemotherapy through hepatic artery using 5-FU, CDDP and MMC].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Acinar Cell; Cisplatin; Drug Administrati | 1996 |
Acinar-islet cell carcinoma presenting as insulinoma.
Topics: Adenoma, Islet Cell; Adult; alpha-Fetoproteins; Antineoplastic Agents; Carcinoma, Acinar Cell; Diagn | 1997 |
[Long-term follow-up and therapeutic control of a hepatic metastatic acinar cell carcinoma of the pancreas using FDG PET].
Topics: Adult; Antimetabolites, Antineoplastic; Carcinoma, Acinar Cell; Fatal Outcome; Female; Fluorodeoxygl | 1998 |
Effective intra-arterial chemotherapy for acinar cell carcinoma of the pancreas.
Topics: Adult; Angiography; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Com | 1999 |