fluorouracil has been researched along with Capillary Leak Syndrome in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Capillary Leak Syndrome: A condition characterized by recurring episodes of fluid leaking from capillaries into extra-vascular compartments causing hematocrit to rise precipitously. If not treated, generalized vascular leak can lead to generalized EDEMA; SHOCK; cardiovascular collapse; and MULTIPLE ORGAN FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Colorectal cancer is the third most common cancer diagnosed in the USA each year." | 1.43 | Systemic capillary leak syndrome in a patient receiving adjuvant oxaliplatin for locally advanced colon cancer. ( Anderson, BJ; Peterson, LL, 2016) |
| "The patient developed systemic capillary leak syndrome during the 16th cycle of chemotherapy." | 1.40 | Trastuzumab-induced systemic capillary leak syndrome in a breast cancer patient. ( Li, Z; Yang, J; Zhang, F, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, F | 1 |
| Yang, J | 1 |
| Li, Z | 1 |
| Anderson, BJ | 1 |
| Peterson, LL | 1 |
2 other studies available for fluorouracil and Capillary Leak Syndrome
| Article | Year |
|---|---|
Trastuzumab-induced systemic capillary leak syndrome in a breast cancer patient.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 2014 |
Systemic capillary leak syndrome in a patient receiving adjuvant oxaliplatin for locally advanced colon cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capillary Leak Syndrome; Colorectal Neoplasms; Fluor | 2016 |