fluorouracil has been researched along with Candidiasis, Oral in 8 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Candidiasis, Oral: Infection of the mucous membranes of the mouth by a fungus of the genus CANDIDA. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "After perioperative adjuvant chemotherapy of a sigma-adenocarcinoma with 400 mg peptichemio and 500 mg 5-fluorouracil a 61-year-old woman developed a severe intoxication: myelosuppression with pancytopenia, gastroenteritis and ulcerative proctitis, toxic hepato- and myocardiopathy, impaired renal function and alopecia." | 7.66 | [Severe intoxication after combined chemotherapy of a sigma-adenocarcinoma with peptichemio and 5-fluorouracil (author's transl)]. ( Gasser, RW; Schmalzl, F, 1982) |
| "Treatment with fluconazole was ineffective, but amphotericin B was curative." | 5.29 | Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole. ( Arranz-Caso, JA; García-Altozano, J; Gomez-Herruz, P; Lopez-Pizarro, VM; Martinez-Martinez, J, 1996) |
| "Forty-five consecutive breast cancer patients, eligible for adjuvant CT with cyclophosphamide, epirubicin or methotrexate, and 5-fluorouracil were followed before, during, 6 months and 1 year after CT and were compared to a control group of 31 breast cancer patients not receiving adjuvant CT." | 3.74 | Oral mucosal lesions, microbial changes, and taste disturbances induced by adjuvant chemotherapy in breast cancer patients. ( Bergmann, OJ; Brünner, N; Jensen, SB; Mouridsen, HT; Nauntofte, B; Reibel, J, 2008) |
| " This prospective cohort study investigated orofacial complications of combination chemotherapy (cyclophosphamide, methotrexate, fluorouracil, vincristine, and prednisone) in women with breast cancer." | 3.68 | Orofacial complications of chemotherapy for breast cancer. ( McCarthy, GM; Skillings, JR, 1992) |
| "After perioperative adjuvant chemotherapy of a sigma-adenocarcinoma with 400 mg peptichemio and 500 mg 5-fluorouracil a 61-year-old woman developed a severe intoxication: myelosuppression with pancytopenia, gastroenteritis and ulcerative proctitis, toxic hepato- and myocardiopathy, impaired renal function and alopecia." | 3.66 | [Severe intoxication after combined chemotherapy of a sigma-adenocarcinoma with peptichemio and 5-fluorouracil (author's transl)]. ( Gasser, RW; Schmalzl, F, 1982) |
| "Major forms of oral candidiasis are pseudomembranous and atrophic form, but chronic hyperplastic candidiasis (CHC) is rarely seen." | 1.37 | Oral candidiasis mimicking tongue cancer. ( Hasegawa, S; Hashikawa, K; Nibu, K; Otsuki, N; Saito, M; Shibata, T; Tahara, S; Yamashita, D, 2011) |
| "Treatment with fluconazole was ineffective, but amphotericin B was curative." | 1.29 | Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole. ( Arranz-Caso, JA; García-Altozano, J; Gomez-Herruz, P; Lopez-Pizarro, VM; Martinez-Martinez, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bertolini, M | 1 |
| Ranjan, A | 1 |
| Thompson, A | 1 |
| Diaz, PI | 1 |
| Sobue, T | 1 |
| Maas, K | 1 |
| Dongari-Bagtzoglou, A | 1 |
| Jensen, SB | 1 |
| Mouridsen, HT | 1 |
| Bergmann, OJ | 1 |
| Reibel, J | 1 |
| Brünner, N | 1 |
| Nauntofte, B | 1 |
| Shibata, T | 1 |
| Yamashita, D | 1 |
| Hasegawa, S | 1 |
| Saito, M | 1 |
| Otsuki, N | 1 |
| Hashikawa, K | 1 |
| Tahara, S | 1 |
| Nibu, K | 1 |
| Gasser, RW | 1 |
| Schmalzl, F | 1 |
| Ueta, E | 1 |
| Osaki, T | 1 |
| Yoneda, K | 1 |
| Yamamoto, T | 1 |
| Umazume, M | 1 |
| Arranz-Caso, JA | 1 |
| Lopez-Pizarro, VM | 1 |
| Gomez-Herruz, P | 1 |
| García-Altozano, J | 1 |
| Martinez-Martinez, J | 1 |
| Ottolenghi, F | 1 |
| Andreassi, L | 1 |
| Sbano, E | 1 |
| Fimiani, M | 1 |
| McCarthy, GM | 1 |
| Skillings, JR | 1 |
8 other studies available for fluorouracil and Candidiasis, Oral
| Article | Year |
|---|---|
Candida albicans induces mucosal bacterial dysbiosis that promotes invasive infection.
Topics: Animals; Antimetabolites; Candida albicans; Candidiasis, Oral; Disease Models, Animal; Dysbiosis; Fe | 2019 |
Oral mucosal lesions, microbial changes, and taste disturbances induced by adjuvant chemotherapy in breast cancer patients.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Al | 2008 |
Oral candidiasis mimicking tongue cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Candidiasis, Oral; | 2011 |
[Severe intoxication after combined chemotherapy of a sigma-adenocarcinoma with peptichemio and 5-fluorouracil (author's transl)].
Topics: Adenocarcinoma; Alopecia; Candidiasis, Oral; Diarrhea; Female; Fluorouracil; Hepatomegaly; Humans; M | 1982 |
Influence of inductive chemoradiotherapy on salivary polymorphonuclear leukocyte (SPMN) functions in oral cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Candidiasis, Oral; Carcinoma, Squamous | 1994 |
Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole.
Topics: Administration, Inhalation; Amphotericin B; Biopsy; Candidiasis; Candidiasis, Oral; Diabetes Complic | 1996 |
[Diffuse chronic mucocutaneous candidiasis: Effects of antimycotics in vitro].
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis, Cutaneous; Candidiasis, Oral; Child; Chroni | 1975 |
Orofacial complications of chemotherapy for breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Candidiasis, Oral; Chi-Squa | 1992 |