fluorouracil has been researched along with Candida Infection in 16 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glutaryl melatonin exhibited mild anti-candidiasis and anti-inflammatory properties." | 7.96 | Glutaryl Melatonin Niosome Gel for Topical Oral Mucositis: Anti- Inflammatory and Anticandidiasis. ( Daduang, J; Damrongrungruang, T; Mahakunakorn, P; Panpitakkul, P; Panyatip, P; Priprem, A; Puthongking, P; Sangchart, P; Somudorn, J; Uthaiwat, P, 2020) |
| "Treatment with fluconazole was ineffective, but amphotericin B was curative." | 5.29 | Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole. ( Arranz-Caso, JA; García-Altozano, J; Gomez-Herruz, P; Lopez-Pizarro, VM; Martinez-Martinez, J, 1996) |
| "Glutaryl melatonin exhibited mild anti-candidiasis and anti-inflammatory properties." | 3.96 | Glutaryl Melatonin Niosome Gel for Topical Oral Mucositis: Anti- Inflammatory and Anticandidiasis. ( Daduang, J; Damrongrungruang, T; Mahakunakorn, P; Panpitakkul, P; Panyatip, P; Priprem, A; Puthongking, P; Sangchart, P; Somudorn, J; Uthaiwat, P, 2020) |
| "The recurrent Candida infection affected primarily the iris and lens, rather than the retina and choroid." | 1.31 | Recurrent endogenous candidal endophthalmitis in a premature infant. ( Calvano, C; Simon, JW; Stern, JH, 2001) |
| "Treatment with fluconazole was ineffective, but amphotericin B was curative." | 1.29 | Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole. ( Arranz-Caso, JA; García-Altozano, J; Gomez-Herruz, P; Lopez-Pizarro, VM; Martinez-Martinez, J, 1996) |
| " On the basis of our findings we have determined the optimal dosage that achieves desired concentrations." | 1.27 | [Monitoring of treatment involving 5-fluorocytosine]. ( Bernard, E; Chichmanian, RM; Dellamonica, P; Fournier, JP; Garraffo, R; Lapalus, P; Le Fichoux, Y; Marty, P, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (37.50) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Damrongrungruang, T | 1 |
| Panpitakkul, P | 1 |
| Somudorn, J | 1 |
| Sangchart, P | 1 |
| Mahakunakorn, P | 1 |
| Uthaiwat, P | 1 |
| Daduang, J | 1 |
| Panyatip, P | 1 |
| Puthongking, P | 1 |
| Priprem, A | 1 |
| Król, J | 1 |
| Nawrot, U | 1 |
| Bartoszewicz, M | 1 |
| Qiu, H | 1 |
| Mao, Y | 1 |
| Gu, Y | 1 |
| Zhu, J | 1 |
| Wang, Y | 1 |
| Zeng, J | 1 |
| Huang, N | 1 |
| Liu, Q | 1 |
| Yang, Y | 1 |
| Ikeda, T | 1 |
| Ishibashi, H | 1 |
| Fujisaki, R | 1 |
| Yamazaki, M | 1 |
| Wakame, K | 1 |
| Kosuna, K | 1 |
| Yamaguchi, H | 1 |
| Ono, Y | 1 |
| Abe, S | 1 |
| Kesavan, C | 1 |
| Joyee, AG | 1 |
| Clemons, KV | 1 |
| Gonzalez, GM | 1 |
| Singh, G | 1 |
| Imai, J | 1 |
| Espiritu, M | 1 |
| Parmar, R | 1 |
| Stevens, DA | 1 |
| Ishitsuka, H | 1 |
| Umeda, Y | 1 |
| Nakamura, J | 1 |
| Yagi, Y | 1 |
| Arranz-Caso, JA | 1 |
| Lopez-Pizarro, VM | 1 |
| Gomez-Herruz, P | 1 |
| García-Altozano, J | 1 |
| Martinez-Martinez, J | 1 |
| Stern, JH | 1 |
| Calvano, C | 1 |
| Simon, JW | 1 |
| Vermes, A | 1 |
| Guchelaar, HJ | 1 |
| van Kuilenburg, AB | 1 |
| Dankert, J | 1 |
| Busey, JF | 1 |
| Sandovsky-Losica, H | 1 |
| Barr-Nea, L | 1 |
| Segal, E | 1 |
| Lamireau, T | 1 |
| Sarlangue, J | 1 |
| Ohlbaum, P | 1 |
| Pontallier, JR | 1 |
| Demarquez, JL | 1 |
| Dellamonica, P | 1 |
| Fournier, JP | 1 |
| Garraffo, R | 1 |
| Lapalus, P | 1 |
| Bernard, E | 1 |
| Chichmanian, RM | 1 |
| Marty, P | 1 |
| Le Fichoux, Y | 1 |
| Yuan, RT | 1 |
| Cohen, MJ | 1 |
| Hermann, J | 1 |
| Plenert, W | 1 |
2 reviews available for fluorouracil and Candida Infection
| Article | Year |
|---|---|
Modern concepts in the diagnosis and management of the pulmonary mycoses.
Topics: Amphotericin B; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidomycosis; Complement Fixation T | 1976 |
[Generalized candida mycoses].
Topics: Amphotericin B; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Burns; Candida albicans; Candidi | 1974 |
1 trial available for fluorouracil and Candida Infection
| Article | Year |
|---|---|
5-fluorocytosine-related bone-marrow depression and conversion to fluorouracil: a pilot study.
Topics: Adult; Aged; beta-Alanine; Biotransformation; Bone Marrow; Candidiasis; Female; Flucytosine; Fluorou | 2002 |
13 other studies available for fluorouracil and Candida Infection
| Article | Year |
|---|---|
Glutaryl Melatonin Niosome Gel for Topical Oral Mucositis: Anti- Inflammatory and Anticandidiasis.
Topics: Administration, Topical; Anhydrides; Animals; Anti-Inflammatory Agents; Antifungal Agents; Candida a | 2020 |
Activity of base analogues (5-fluorouracil, 5-flucytosine) against planktonic cells and mature biofilm of Candida yeast. Effect of combination with folinic acid.
Topics: Antifungal Agents; Biofilms; Candida albicans; Candida glabrata; Candidiasis; Drug Resistance, Funga | 2019 |
The potential of photodynamic therapy to treat esophageal candidiasis coexisting with esophageal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Candidiasis; Endoscopy; Esophageal Neoplasms | 2014 |
[Prophylactic efficacy of a basidiomycetes preparation AHCC against lethal Candida albicans infection in experimental granulocytopenic mice].
Topics: Adjuvants, Immunologic; Administration, Oral; Agranulocytosis; Animals; Basidiomycota; Candidiasis; | 2003 |
5-fluorouracil altered morphology and inhibited growth of Candida albicans.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Culture Media; Fluorouracil; Humans; Microbial Sen | 2005 |
Development of an orogastrointestinal mucosal model of candidiasis with dissemination to visceral organs.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Colony Count, Microbial; Disease Models, | 2006 |
Protective activity of thymosin against opportunistic infections in animal models.
Topics: Animals; Candida albicans; Candidiasis; Drug Administration Schedule; Enterobacteriaceae Infections; | 1983 |
Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole.
Topics: Administration, Inhalation; Amphotericin B; Biopsy; Candidiasis; Candidiasis, Oral; Diabetes Complic | 1996 |
Recurrent endogenous candidal endophthalmitis in a premature infant.
Topics: Amphotericin B; Betaxolol; Candida albicans; Candidiasis; Drug Therapy, Combination; Endophthalmitis | 2001 |
Fatal systemic candidiasis of gastrointestinal origin: an experimental model in mice compromised by anti-cancer treatment.
Topics: Animals; Candida albicans; Candidiasis; Cecum; Chemotherapy, Adjuvant; Disease Models, Animal; Esoph | 1992 |
[Multifocal Candida albicans osteoarthritis in an infant].
Topics: Amphotericin B; Candidiasis; Drug Therapy, Combination; Fluorouracil; Humans; Iatrogenic Disease; In | 1988 |
[Monitoring of treatment involving 5-fluorocytosine].
Topics: Amphotericin B; Candidiasis; Cytosine; Dose-Response Relationship, Drug; Drug Interactions; Drug The | 1985 |
Candida albicans tenosynovitis of the hand.
Topics: Amphotericin B; Candidiasis; Child; Fluorouracil; Hand; Humans; Hypergammaglobulinemia; Male; Tendon | 1985 |