fluorouracil has been researched along with Cancer of the Fallopian Tube in 10 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Only one patient required a dosage adjustment of cisplatin for a serum creatinine elevation >2." | 2.69 | Phase II trial of combination intraperitoneal cisplatin and 5-fluorouracil in previously treated patients with advanced ovarian cancer: long-term follow-up. ( Braly, P; Doroshow, JH; Johnson, D; Kogut, N; Leong, L; Longmate, J; Margolin, K; McNamara, M; Morgan, RJ; Nagasawa, S; Najera, L; Raschko, J; Schinke, S; Shibata, S; Somlo, G, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CHAN, DP | 1 |
| HO, JH | 1 |
| WOO, AW | 1 |
| Rischin, D | 1 |
| Phillips, KA | 1 |
| Friedlander, M | 1 |
| Harnett, P | 1 |
| Quinn, M | 1 |
| Richardson, G | 1 |
| Martin, A | 1 |
| Rosa, DD | 1 |
| Awada, A | 1 |
| Mano, MS | 1 |
| Selleslags, J | 1 |
| Lebrun, F | 1 |
| Gil, T | 1 |
| Piccart, MJ | 1 |
| D'Hondt, V | 1 |
| Schulz, BO | 1 |
| Hof, K | 1 |
| Friedrich, HJ | 1 |
| Weppelmann, B | 1 |
| Krebs, D | 1 |
| Massad, LS | 1 |
| Wagley, E | 1 |
| Winkelman, L | 1 |
| Lincoln, S | 1 |
| Yordan, EL | 1 |
| de Geest, K | 1 |
| Wilbanks, GD | 1 |
| Morgan, RJ | 1 |
| Braly, P | 1 |
| Leong, L | 1 |
| Shibata, S | 1 |
| Margolin, K | 1 |
| Somlo, G | 1 |
| McNamara, M | 1 |
| Longmate, J | 1 |
| Schinke, S | 1 |
| Raschko, J | 1 |
| Nagasawa, S | 1 |
| Kogut, N | 1 |
| Najera, L | 1 |
| Johnson, D | 1 |
| Doroshow, JH | 1 |
| Ryuko, K | 1 |
| Iwanari, O | 1 |
| Moriyama, M | 2 |
| Nakayama, S | 1 |
| Miyako, J | 1 |
| Kitao, M | 1 |
| Fuller, AF | 1 |
| Krane, IM | 1 |
| Budzik, GP | 1 |
| Donahoe, PK | 1 |
| Erez, S | 1 |
| Kaplan, AL | 1 |
| Wall, JA | 1 |
| Malkasian, GD | 1 |
| Decker, DG | 1 |
| Mussey, E | 1 |
| Johnson, CE | 1 |
3 trials available for fluorouracil and Cancer of the Fallopian Tube
| Article | Year |
|---|---|
A phase II trial of capecitabine in heavily pre-treated platinum-resistant ovarian cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Drug Resistance, Neoplasm | 2004 |
Oxaliplatin/5fluorouracil-based chemotherapy was active and well tolerated in heavily pretreated patients with ovarian carcinoma.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cohort Studi | 2008 |
Phase II trial of combination intraperitoneal cisplatin and 5-fluorouracil in previously treated patients with advanced ovarian cancer: long-term follow-up.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Disease-Free Surv | 2000 |
7 other studies available for fluorouracil and Cancer of the Fallopian Tube
| Article | Year |
|---|---|
A REPORT OF THE SYSTEMIC USE OF 5-FLUOROURACIL IN THE TREATMENT OF CHINESE CANCER PATIENTS.
Topics: Adenocarcinoma; Aged; Breast Neoplasms; Carcinoma; Carcinoma, Squamous Cell; China; Fallopian Tube N | 1964 |
[Platin-containing cytostatic combinations in the therapy of advanced gynecologic carcinomas].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Cisplatin; Cyclop | 1984 |
Salvage mitomycin/5-fluorouracil after platinum-based therapy for women with advanced ovarian cancer and related gynecologic malignancies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Fallopian Tube Neoplasms; Female; Fluor | 1994 |
[Intraperitoneal chemotherapy through implantable injection port in patients with advanced ovarian (or tubal) carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Drug Administra | 1991 |
Mullerian inhibiting substance reduction of colony growth of human gynecologic cancers in a stem cell assay.
Topics: Adenocarcinoma; Altretamine; Anti-Mullerian Hormone; Ascitic Fluid; Carcinoma; Chromatography, Affin | 1985 |
Clinical staging of carcinoma of the uterine tube.
Topics: Adult; Aged; Barium; Carcinoma; Fallopian Tube Neoplasms; Female; Fluorouracil; Humans; Middle Aged; | 1967 |
Observations on gynecologic malignancy treated with 5-fluorouracil.
Topics: Adult; Age Factors; Aged; Fallopian Tube Neoplasms; Female; Fluorouracil; Genital Neoplasms, Female; | 1968 |