Page last updated: 2024-10-27

fluorouracil and Cancer of Rectum

fluorouracil has been researched along with Cancer of Rectum in 2610 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Fluorouracil, leucovorin, and irinotecan (FOLFIRI) plus bevacizumab is the standard second-line chemotherapy for patients with metastatic colorectal cancer (mCRC) who are refractory or intolerant to fluoropyrimidines and oxaliplatin."9.69Impact of omitting fluorouracil from FOLFIRI plus bevacizumab as second-line chemotherapy for patients with metastatic colorectal cancer. ( Ando, M; Bando, H; Honda, K; Kadowaki, S; Kato, K; Masuishi, T; Matsubara, Y; Muro, K; Nakazawa, T; Narita, Y; Nozawa, K; Ogata, T; Tajika, M; Taniguchi, H, 2023)
"The PanaMa trial demonstrated significant benefit in progression-free survival with the addition of panitumumab (Pmab) to fluorouracil and folinic acid (FU/FA) as maintenance therapy following first-line induction therapy with FOLFOX/Pmab in patients with RAS wild-type metastatic colorectal cancer."9.69Health-related quality of life in patients with RAS wild-type metastatic colorectal cancer treated with fluorouracil and folinic acid with or without panitumumab as maintenance therapy: a prespecified secondary analysis of the PanaMa (AIO KRK 0212) trial. ( Alig, AHS; Ballhausen, A; Fruehauf, S; Goekkurt, E; Graeven, U; Heinemann, V; Heinrich, K; Held, S; Karthaus, M; Kasper, S; König, AO; Kurreck, A; Meyer-Knees, JW; Modest, DP; Müller, L; Sommerhäuser, G; Stahler, A; Stintzing, S; Trarbach, T; von Weikersthal, LF, 2023)
"The randomised open-label phase III XELAVIRI trial failed to demonstrate non-inferiority of the sequential application of fluoropyrimidine plus bevacizumab followed by additional irinotecan at first progression (Arm A) versus initial combination of all agents (Arm B) for untreated metastatic colorectal cancer in the initial analysis of time-to-failure-of-strategy (TFS, 90% confidence boundary of 0."9.51First-line fluoropyrimidine plus bevacizumab followed by irinotecan-escalation versus initial fluoropyrimidine, irinotecan and bevacizumab in patients with metastatic colorectal cancer - Final survival and per-protocol analysis of the randomised XELAVIRI ( Decker, T; Denzlinger, C; Fischer von Weikersthal, L; Gießen-Jung, C; Graeven, U; Heinemann, V; Heinrich, K; Held, S; Jung, A; Kaiser, F; Kirchner, T; Kurreck, A; Modest, DP; Neumann, J; Schenk, M; Schwaner, I; Stahler, A; Stintzing, S, 2022)
"This study examined the association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms and survival of patients with colorectal cancer (CRC) treated with 5-fluorouracil (5-FU)-based chemotherapy in Taiwan."9.24Polymorphisms of MTHFR C677T and A1298C associated with survival in patients with colorectal cancer treated with 5-fluorouracil-based chemotherapy. ( Chang, SN; Hsieh, LL; Lai, CY; Lin, YK; Sung, FC; Tang, R; Yeh, CC, 2017)
"Between October 2006 and December 2009, 36 patients with non-metastatic rectal adenocarcinoma were treated with chemoradiotherapy of irinotecan (50 mg/m(2) weekly), 5-fluorouracil (250 mg/m(2) for 5 days/week) and pelvic radiation (45 Gy/1."9.16Combination of irinotecan and 5-fluorouracil with radiation in locally advanced rectal adenocarcinoma. ( El-Hadaad, HA; Roshdy, S; Wahba, HA, 2012)
"A regimen consisting of 5-fluorouracil/leucovorin plus oxaliplatin (FOLFOX-6) is widely used in France in the first-line treatment of metastatic colorectal cancer (MCRC)."9.15Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/leucovorin plus oxaliplatin (FOLFOX-6) as first-line treatment for metastatic colorectal cancer. ( Adenis, A; Bennouna, J; Bergougnoux, L; Conroy, T; Douillard, JY; Ducreux, M; Faroux, R; Hebbar, M; Kockler, L; Lledo, G; Rebischung, C; Ychou, M, 2011)
"Oxaliplatin combined with either fluorouracil/leucovorin (OXAFAFU) or capecitabine (OXXEL) has a demonstrated activity in metastatic colorectal cancer patients."9.14Randomised trial comparing biweekly oxaliplatin plus oral capecitabine versus oxaliplatin plus i.v. bolus fluorouracil/leucovorin in metastatic colorectal cancer patients: results of the Southern Italy Cooperative Oncology study 0401. ( Barberis, G; Cannone, M; Comella, P; Condemi, G; Farris, A; Filippelli, G; Maiorino, L; Massidda, B; Natale, D; Palmeri, S, 2009)
"Forty-two rectal carcinoma (T(3-4)N(0-2)M(0)) patients with grade 2 or 3 diarrhea refractory to loperamide were enrolled to receive octreotide."9.12Octreotide in the management of chemoradiotherapy-induced diarrhea refractory to loperamide in patients with rectal carcinoma. ( Karaoglu, A; Topkan, E, 2006)
"Seventy-two patients suffering from a metastatic colorectal cancer received, as first line treatment, a combination chronotherapy with 5-FU and folinic acid (infused from 10 pm to 10 am with a peak at 4 am, respectively at doses of 700 and 300 mg/m2 per day) and carboplatin (infused at the dose of 40 mg/m2 per day from 10 am to 10 pm with a peak at 4 pm)."9.11[Chronotherapy combining 5-fluorouracil, folinic acid and carboplatin as first line treatment in metastatic colorectal cancer. A phase 2 study]. ( Biquet, JF; David, A; Delforge, M; Focan, C; Focan-Henrard, D; Graas, MP; Kreutz, F; Longrée, L; Materne, R; Moeneclaey, N; Weerts, J, 2005)
"To assess the toxicity and the efficacy of preoperative radiotherapy with continuous infusion 5-fluorouracil (5-FU) for locally advanced adenocarcinoma of the rectum."9.09Early toxicity from preoperative radiotherapy with continuous infusion 5-fluorouracil for resectable adenocarcinoma of the rectum: a Phase II trial for the Trans-Tasman Radiation Oncology Group. ( Bell, A; Burmeister, BH; Fisher, R; Goldstein, D; Joseph, D; Kneebone, A; MacKay, JR; Ngan, SY; Rischin, D; Schache, DJ, 2001)
"Data from 12 metastatic colorectal cancer patients who were submitted to a pilot study with a multistep subcutaneous (sc) low dose recombinant interleukin-2 (rIL-2), 5-fluorouracil (5-FU) and leucovorin (LV) administration were compared with those from 13 historical controls who were comparable for the major prognostic indices."9.08A multistep therapy with subcutaneous low dose recombinant interleukin-2, 5-fluorouracil and leucovorin prolongs the response of metastatic colorectal cancer patients: a pilot study. ( Anselmi, L; Carpi, A; Ferrari, P; Nicolini, A; Sagripanti, A, 1998)
"To evaluate the contribution of semustine (MeCCNU) to adjuvant benefit, previously untreated patients with histologically proven adenocarcinoma of the rectum who had undergone curative resection were randomized to treatment with combination radiation therapy and fluorouracil (5-FU) followed by either 12 months of 5-FU and MeCCNU or 6 months of escalating 5-FU."9.07Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum. Gastrointestinal Tumor Study Group. ( , 1992)
"Seventy-seven patients with previously untreated, measurable, histologically confirmed, metastatic adenocarcinoma of the rectum or sigmoid were randomized to receive either epirubicin 90 mg/m2 (75 mg/m2 if prior radiotherapy) i."9.06A phase III randomized trial of epirubicin versus 5-fluorouracil in metastatic rectal/sigmoid adenocarcinoma. ( Blum, RH; Lafleur, F; Molinaro, P, 1989)
"We report the results of an expanded trial of 5-fluorouracil (5-FU) combined with high-dose folinic acid for treatment of patients with advanced colorectal or advanced gastric adenocarcinoma."9.06Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid. ( Chollet, P; Fourtillan, JB; Goldschmidt, E; Machover, D; Marquet, J; Metzger, G; Misset, JL; Schwarzenberg, L; Vandenbulcke, JM; Zittoun, J, 1986)
"Thirty-four patients with advanced adenocarcinoma of the gastrointestinal tract have been treated with high-dose 5-fluorouracil modulated by concomitant allopurinol therapy, in combination with either razoxane or adriamycin."9.05A trial of high-dose 5-fluorouracil with razoxane or adriamycin in the treatment of advanced adenocarcinoma of the gastrointestinal tract. ( Ashford, RF; Bakowski, M; Evans, M; Hellman, K; Jones, R; Lambert, J; Newton, K; Peters, N; Phillips, R; Smith, BJ, 1983)
"In a randomized series of 70 patients with with colo rectal adenocarcinoma, a comparison of systemic 5-fluorouracil chemotherapy administered as a continuous 120-hours infusion vs."9.04Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma. ( Baker, LH; Reed, ML; Seifert, P; Vaitkevicius, VK, 1975)
"Adjuvant capecitabine monotherapy is an option for colon and upper rectum adenocarcinoma patients, providing they have stage II disease with an intermediate risk of recurrence, or stage III but they are above 70's or they have comorbidities."8.31Incidence of Disease Recurrence in Patients With Colon and Upper Rectum Adenocarcinoma Stage II and III Receiving Adjuvant Capecitabine Monotherapy: Do Number of Chemotherapy Cycles and Relative Dose Intensity of the Drug Play a Role? ( Aravantinos, G; Dessypris, N; Gkoura, S; Karampinos, K; Mauri, D; Miaris, N; Samantas, E; Sgouros, J; Spathas, N; Stamoulis, G; Theodoropoulos, I; Tzoudas, F; Visvikis, A, 2023)
"To evaluate the efficacy and safety of apatinib combined with FOLFIRI in the first-line treatment of advanced metastatic colorectal cancer (mCRC) and explore potential factors of efficacy."8.12Efficacy of apatinib combined with FOLFIRI in the first-line treatment of patients with metastatic colorectal cancer. ( Liu, H; Rong, X; Wang, J; Wang, Y; Yu, H; Zhao, J, 2022)
"To compare the efficacy and safety of folinic acid, fluorouracil and irinotecan (FOLFIRI) plus bevacizumab or aflibercept in metastatic colorectal cancer (mCRC) patients pretreated with oxaliplatin-based chemotherapy."8.12A Comparison of Folinic Acid, Fluorouracil and Irinotecan (FOLFIRI) plus Bevacizumab and FOLFIRI plus Aflibercept as Second-line Treatment for Metastatic Colorectal Cancer. ( Hong, JY; Jo, H; Kang, WK; Kim, H; Kim, ST; Lee, J; Lee, MS; Lee, YP; Lim, HY; Park, JO; Park, SH; Park, YS, 2022)
"The oral fluoropyrimidine S-1 has shown comparable efficacy to capecitabine in Asian and some Western studies on metastatic colorectal cancer."8.12Long-Term Safety Data on S-1 Administered After Previous Intolerance to Capecitabine-Containing Systemic Treatment for Metastatic Colorectal Cancer. ( Kwakman, JJM; Mol, L; Punt, CJA, 2022)
"Ocular toxicity derived from the use of systemic fluorouracil has been widely described in the literature, as well as the relationship between the use of capecitabine and the appearance of conjunctivitis."8.12Conjunctivitis associated with capecitabine treatment in a patient with colon cancer: The importance on educating patients into identifying adverse reactions. ( Bello Crespo, M; Gajete Pablos, MA; Gioseffi, HA; Roa García, DM; Trujillano Ruiz, A, 2022)
"Five-fluorouracil, folinic acid, oxaliplatin and irinotecan (FOLFOXIRI) regimen is used as the first-line treatment for metastatic colorectal cancer (mCRC)."8.12Safety and efficacy of irinotecan, oxaliplatin, and capecitabine (XELOXIRI) regimen with or without targeted drugs in patients with metastatic colorectal cancer: a retrospective cohort study. ( Gao, L; Liu, X; Ma, X; Ou, K; Wang, Q; Yang, L; Zhang, H, 2022)
"a capecitabine and oxaliplatin drug combination regimen has shown a survival benefit in patients with advanced colorectal cancer, yet its administration represents an attractive option for low resource settings."8.12Capecitabine plus oxaliplatin in the treatment of metastatic colorectal cancer at Tygerberg Hospital: a retrospective study. ( Begg, W; Kibudde, S, 2022)
"Female patients and patients aged sixty-five or older had an increased risk of developing severe diarrhea during preoperative chemoradiation therapy with capecitabine."8.02Relation between body composition and severe diarrhea in patients treated with preoperative chemoradiation with capecitabine for rectal cancer: a single-centre cohort study. ( Hartman, W; Nuyttens, JJME; Oomen-de Hoop, E; Rothbarth, J; van Meerten, E; van Rees, JM; van Vugt, JLA; Verhoef, C, 2021)
"5-fluorouracil chemotherapy in patients with dihydropyrimidine dehydrogenase deficiency, can give rise to ocular and cutaneous toxicity."7.77A bilateral cicatricial ectropion and bilateral upper lid shortening caused by 5-fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency. ( Kemp, E; McDonald, A; Obi, EE, 2011)
"Over a period of 1 year in our hospital, 3 patients were diagnosed with 'ileitis following capecitabine use'."7.77[Ileitis following capecitabine use]. ( Bouma, G; Imholz, AL, 2011)
"Failure rate of colorectal cancer after surgical resection remains around 50% and adjuvant treatments are clearly required."7.77Large scale trial for adjuvant treatment in high risk resected colorectal cancers. Rationale to test the combination of loco-regional and systemic chemotherapy and to compare l-leucovorin + 5-FU to levamisole + 5-FU. ( Nordlinger, B; Rougier, P, 1993)
"A case of acute heart failure due to Takotsubo cardiomyopathy induced by 5-fluorouracil is described."7.75A case of Takotsubo cardiomyopathy during 5-fluorouracil treatment for rectal adenocarcinoma. ( Hata, N; Kobayashi, N; Mizuno, K; Shinada, T; Shirakabe, A; Yokoyama, S, 2009)
"We present a case of hand-foot syndrome (HFS) induced by bolus 5-fluorouracil (5-FU) therapy."7.74[A case report of a patient with hand-foot syndrome induced by bolus 5-fluorouracil therapy]. ( Aoyagi, H; Enomoto, M; Higuchi, T; Iida, S; Ishikawa, T; Kobayashi, H; Matsuyama, T; Sugihara, K; Uetake, H; Yasuno, M, 2008)
"Headaches have been reported as a potential side effect of capecitabine therapy."7.74Capecitabine-induced headache responding to diltiazem. ( Fakih, MG; Raman, AK, 2007)
"The levels of both VEGF and PDGF-BB were measured in three time points, in the serum of 32 rectal carcinoma patients receiving daily reduced-dose/continuous capecitabine in combination with preoperative pelvic irradiation."7.74Daily low-dose/continuous capecitabine combined with neo-adjuvant irradiation reduces VEGF and PDGF-BB levels in rectal carcinoma patients. ( Be'ery, E; Fenig, E; Koren, C; Lavi, I; Loven, D; Shaked, Y; Sulkes, A; Yerushalmi, R, 2008)
"During a 4-year period we treated 20 patients with locally advanced adenocarcinoma of the rectum using a protocol of preoperative simultaneous pelvic irradiation (4,030-6,040 cGy) and infusion chemotherapy (5-fluorouracil 100 mg/m2 per day over 96 hours and mitomycin 10 mg/m2) followed by surgical resection."7.70Combined preoperative radiation and mitomycin/5-fluorouracil treatment for locally advanced rectal adenocarcinoma. ( Burke, SJ; Knight, DC; Kwasnik, EM; Percarpio, BA, 1998)
"To report 5-fluorouracil in combination with folinic acid as a cause of severe nonischemic heart failure and to demonstrate the potential usefulness of an intra-aortic balloon pump."7.70Severe heart failure secondary to 5-fluorouracil and low-doses of folinic acid: usefulness of an intra-aortic balloon pump. ( David, JS; Gaussorgues, P; Gueugniaud, PY; Hepp, A; Petit, P, 2000)
"Thymidylate synthase (TS) expression in colorectal cancer metastases has been shown to predict for the clinical response to 5-fluorouracil."7.70Thymidylate synthase protein expression in primary colorectal cancer compared with the corresponding distant metastases and relationship with the clinical response to 5-fluorouracil. ( Aschele, C; Debernardis, D; Maley, F; Sobrero, A; Tunesi, G, 2000)
"Based on the in vitro and in vivo data suggesting synergistic cytolysis by the combination of 5-fluorouracil and interferon-gamma against a variety of malignant cell lines including a human colon carcinoma cell line (HT-29), we initiated studies in patients with advanced colon or rectal carcinoma."7.67Phase I and II studies of the combination of recombinant human interferon-gamma and 5-fluorouracil in patients with advanced colorectal carcinoma. ( Abbruzzese, JL; Ajani, JA; Edwards, C; Ende, K; Faintuch, JS; Gutterman, JU; Levin, B; Rios, AA; Saks, S, 1989)
"Cardiac symptoms, including hypotension, developed in three patients with advanced colorectal carcinoma while being treated with cisplatin (CDDP) and 5-fluorouracil (5-FU)."7.67Hypotension as a manifestation of cardiotoxicity in three patients receiving cisplatin and 5-fluorouracil. ( Jakubowski, AA; Kemeny, N, 1988)
"Thirteen patients with metastatic colorectal adenocarcinoma underwent treatment with continuous ambulatory 5-fluorouracil (5-FU) infusion 300 mg/m2/day and intermittent bolus methotrexate (MTX) (200 mg/m2) with calcium leucovorin (LCV) 10 mg/m2 orally every 6 h X four to eight doses given 24 h after MTX."7.67Continuous 5-fluorouracil infusion and pulse methotrexate/leucovorin for colorectal adenocarcinoma. A report of excessive toxicity. ( Anderson, T; Frick, J; Hansen, RM; Quebbeman, EJ; Ritch, PS, 1987)
"We report the results of an expanded trial of 5-fluorouracil (FUra) combined with high-dose folinic acid for treatment of patients with advanced colorectal or gastric adenocarcinoma."7.67Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid. ( Benavides, M; Chollet, P; Goldschmidt, E; Machover, D; Marquet, J; Metzger, G; Misset, JL; Schwarzenberg, L; Vandenbulcke, JM; Zittoun, J, 1987)
"To delineate the efficacy of continuous intravenous 5-fluorouracil (5-FU) infusion therapy for advanced colorectal adenocarcinoma, a study of 36 patients with measurable metastatic disease was conducted."7.67Long-term ambulatory treatment of metastatic colorectal adenocarcinoma by continuous intravenous infusion of 5-fluorouracil. ( Ausman, R; Becker, T; Blake, D; Caballero, G; Hansen, R; Jenkins, D; Quebbeman, E; Ritch, P; Schulte, W; Tangen, L, 1985)
"The modulation of 5-fluorouracil (FUra) metabolism by methotrexate (MTX) pretreatment in monolayer cultures of human colorectal adenocarcinoma."7.66Modulation of 5-fluorouracil metabolism and cytotoxicity by antimetabolite pretreatment in human colorectal adenocarcinoma HCT-8. ( Benz, C; Cadman, E, 1981)
"DPD deficiency was suspected because he developed many severe adverse events of capecitabine early and was finally confirmed based on the finding of a low DPD activity level in peripheral blood mononuclear cells."6.82Severe Gastrointestinal Disorder Due to Capecitabine Associated with Dihydropyrimidine Dehydrogenase Deficiency: A Case Report and Literature Review. ( Akutsu, D; Fukuda, S; Hagiwara, Y; Ikeda, N; Inagaki, Y; Kobayashi, M; Moriwaki, T; Narasaka, T; Niisato, Y; Onoda, T; Suzuki, H; Tange, Y; Tomisaki, R; Tsuchiya, K; Tsuji, M; Yamada, K; Yamada, T; Yamamoto, Y, 2022)
"With the changed dosing schedule, this regimen was very well tolerated."6.82Phase I study of pre-operative continuous 5-FU and sorafenib with external radiation therapy in locally advanced rectal adenocarcinoma. ( Almhanna, K; Campos, T; Chen, DT; Hoffe, SE; Jiang, K; Kim, R; Prithviraj, GK; Shibata, D; Shridhar, R; Strosberg, J; Zhao, X, 2016)
"Capecitabine was given at 725 mg/m(2) orally twice daily Monday through Friday concurrently with RT."6.73Phase II study of weekly intravenous oxaliplatin combined with oral daily capecitabine and radiotherapy with biologic correlates in neoadjuvant treatment of rectal adenocarcinoma. ( Andrews, C; Bullarddunn, K; Fakih, MG; Levea, C; Park, YM; Pendyala, L; Puthillath, A; Rajput, A; Ross, ME; Rustum, YM; Toth, K; Yang, GY, 2008)
"Eniluracil and 5-FU were given with a 5-week course of preoperative radiotherapy of 4500 cGy, with a possible 540-cGy boost."6.71A Phase I trial of preoperative eniluracil plus 5-fluorouracil and radiation for locally advanced or unresectable adenocarcinoma of the rectum and colon. ( Anscher, MS; Cohen, DP; Czito, BG; Ertel, PJ; Honeycutt, W; Hong, TJ; Hurwitz, HI; Lee, CG; Lockhart, AC; Ludwig, KA; Mangum, SG; Mantyh, C; Morse, MA; Petros, WP; Seigler, HF; Spector, NL; Tyler, DS, 2004)
"The purpose of our study was to determine the maximum-tolerated dose, dose-limiting toxicity, safety profile, and pharmacokinetics of the polyamine synthesis inhibitor SAM486A given in combination with 5-fluorouracil/leucovorin (5-FU/LV) in cancer patients."6.71Phase I and pharmacokinetic study of the polyamine synthesis inhibitor SAM486A in combination with 5-fluorouracil/leucovorin in metastatic colorectal cancer. ( Bootle, D; Bridgewater, J; Choi, L; de Bruijn, P; Eskens, FA; Ledermann, JA; Mueller, C; Planting, AS; Sklenar, I; Sparreboom, A; van Zuylen, L; Verweij, J, 2004)
"All patients had metastatic colorectal cancer, with adjuvant or palliative chemotherapy given to six patients (22%) on schedule A and 12 patients on schedule B (41%)."6.69Continuous delivery of venous 5-fluorouracil and arterial 5-fluorodeoxyuridine for hepatic metastases from colorectal cancer: feasibility and tolerance in a randomized phase II trial comparing flat versus chronomodulated infusion. ( Adam, R; Bismuth, H; Dallemagne, B; Focan, C; Focan-Henrard, D; Jasmin, C; Jehaes, C; Kreutz, F; Levi, F; Lobelle, JP; Markiewicz, S; Misset, JL; Weerts, J, 1999)
"5-Fluorouracil (5-FU) is a commonly used anti-neoplastic agent."6.47Symptomatic 5-fluorouracil-induced sinus bradycardia. ( Lee, AD; McKay, MJ, 2011)
" The efficacy and adverse effects of maintenance treatment were compared between the two groups."5.72Efficacy and safety analysis of bevacizumab combined with capecitabine in the maintenance treatment of RAS-mutant metastatic colorectal cancer. ( Cha, Y; Huang, W; Tian, Y; Xiong, H; Yuan, X; Zhang, H, 2022)
"Fluorouracil, leucovorin, and irinotecan (FOLFIRI) plus bevacizumab is the standard second-line chemotherapy for patients with metastatic colorectal cancer (mCRC) who are refractory or intolerant to fluoropyrimidines and oxaliplatin."5.69Impact of omitting fluorouracil from FOLFIRI plus bevacizumab as second-line chemotherapy for patients with metastatic colorectal cancer. ( Ando, M; Bando, H; Honda, K; Kadowaki, S; Kato, K; Masuishi, T; Matsubara, Y; Muro, K; Nakazawa, T; Narita, Y; Nozawa, K; Ogata, T; Tajika, M; Taniguchi, H, 2023)
"AtezoTRIBE phase II randomized study demonstrated that adding atezolizumab to first-line FOLFOXIRI (5-fluorouracil, oxaliplatin, irinotecan) plus bevacizumab prolongs progression-free survival (PFS) of patients with metastatic colorectal cancer (mCRC), with a modest benefit among proficient mismatch repair (pMMR)."5.69An Immune-Related Gene Expression Signature Predicts Benefit from Adding Atezolizumab to FOLFOXIRI plus Bevacizumab in Metastatic Colorectal Cancer. ( Antoniotti, C; Bensi, M; Bergamo, F; Boccaccino, A; Boquet, I; Catteau, A; Conca, V; Cremolini, C; Galon, J; Giordano, M; Leonetti, S; McGregor, K; Morano, F; Murgioni, S; Nielsen, TJ; Papiani, G; Passardi, A; Pietrantonio, F; Ross, DT; Rossini, D; Salvatore, L; Schweitzer, BL; Seitz, R; Tamburini, E; Varga, MG, 2023)
"The PanaMa trial demonstrated significant benefit in progression-free survival with the addition of panitumumab (Pmab) to fluorouracil and folinic acid (FU/FA) as maintenance therapy following first-line induction therapy with FOLFOX/Pmab in patients with RAS wild-type metastatic colorectal cancer."5.69Health-related quality of life in patients with RAS wild-type metastatic colorectal cancer treated with fluorouracil and folinic acid with or without panitumumab as maintenance therapy: a prespecified secondary analysis of the PanaMa (AIO KRK 0212) trial. ( Alig, AHS; Ballhausen, A; Fruehauf, S; Goekkurt, E; Graeven, U; Heinemann, V; Heinrich, K; Held, S; Karthaus, M; Kasper, S; König, AO; Kurreck, A; Meyer-Knees, JW; Modest, DP; Müller, L; Sommerhäuser, G; Stahler, A; Stintzing, S; Trarbach, T; von Weikersthal, LF, 2023)
"Cetuximab in combination with chemotherapy is a standard first-line treatment regimen for patients with metastatic colorectal cancer (mCRC) RAS wild-type (wt); however, the efficacy of cetuximab plus leucovorin, fluorouracil and oxaliplatin (FOLFOX) had never been demonstrated in a prospective, randomized, controlled phase III study."5.51[The TAILOR study establishes, in patients mCRC wt, the first line use of FOLFOX in combination with cetuximab]. ( Colombo, A; Porretto, CM; Rosati, G, 2022)
"The randomised open-label phase III XELAVIRI trial failed to demonstrate non-inferiority of the sequential application of fluoropyrimidine plus bevacizumab followed by additional irinotecan at first progression (Arm A) versus initial combination of all agents (Arm B) for untreated metastatic colorectal cancer in the initial analysis of time-to-failure-of-strategy (TFS, 90% confidence boundary of 0."5.51First-line fluoropyrimidine plus bevacizumab followed by irinotecan-escalation versus initial fluoropyrimidine, irinotecan and bevacizumab in patients with metastatic colorectal cancer - Final survival and per-protocol analysis of the randomised XELAVIRI ( Decker, T; Denzlinger, C; Fischer von Weikersthal, L; Gießen-Jung, C; Graeven, U; Heinemann, V; Heinrich, K; Held, S; Jung, A; Kaiser, F; Kirchner, T; Kurreck, A; Modest, DP; Neumann, J; Schenk, M; Schwaner, I; Stahler, A; Stintzing, S, 2022)
"The addition of aflibercept to the fluorouracil and irinotecan (FOLFIRI) regimen significantly improved clinical outcomes in patients with metastatic colorectal cancer (CRC) previously treated with oxaliplatin."5.51Efficacy and safety of folfiri plus aflibercept in second-line treatment of metastatic colorectal cancer: Real-life data from Turkish oncology group. ( Acar, R; Akbas, S; Akinci, MB; Araz, M; Arslan, C; Artac, M; Bahceci, A; Bilgetekin, I; Bilici, A; Cakir, E; Celik, E; Cilbir, E; Cincin, I; Dede, DS; Demirkiran, A; Deniz, GI; Dogan, I; Erdem, D; Erdogan, AP; Eren, OO; Erol, C; Garbioglu, DB; Gulmez, A; Hacibekiroglu, I; Hamdard, J; Hizal, M; Inal, A; Kahraman, S; Kaya, AO; Koca, S; Kubilay, P; Kucukarda, A; Kut, E; Mandel, NM; Menekse, S; Nayir, E; Oksuzoglu, B; On, S; Oyman, A; Ozyukseler, DT; Paydas, S; Sakin, A; Sen, E; Sendur Mehmet, AN; Sevinc, A; Taskaynatan, H; Tastekin, D; Turhal, S; Uncu, D; Yalcin, B; Yildirim, ME, 2022)
"A 35-year-old woman was diagnosed with rectal cancer with metastasis to the liver."5.51Rechallenge capecitabine after fluoropyrimidine-induced cardiotoxicity in rectal cancer: A case report. ( Ouyang, Y; Peng, T; Tong, K, 2019)
"Aflibercept; a decoy receptor for vascular endothelial growth factors (VEGFs) and placental growth factor (PLGF), in combination with FOLFIRI (leucovorin calcium, fluorouracil, irinotecan hydrochloride) chemotherapy regime, was FDA approved in 2012 as second-line salvage chemotherapy for metastatic colorectal cancer (mCRC)."5.41A systemic review and meta-analysis of Aflibercept plus FOLFIRI regimen as a second-line treatment for metastatic colorectal cancer: A PRISMA compliant pooled analysis of randomized controlled trials and single arm studies to assess efficacy and safety. ( Chorawala, MR; Patel, RS; Thakur, A, 2023)
"We encountered a case of colorectal cancer with pelvic abscess treated with radical surgery following colostomy and chemotherapy."5.39[A case of locally advanced colorectal cancer with abscess responding to 5-fluorouracil, leucovorin, and oxaliplatin plus bevacizumab]. ( Goseki, N; Kuwabara, H; Liu, B; Mitsuoka, A; Nakajima, K; Sanada, T; Watanabe, S, 2013)
"Radiation enteritis is the main acute side-effect during pelvic irradiation."5.34Dose-volume relationships between enteritis and irradiated bowel volumes during 5-fluorouracil and oxaliplatin based chemoradiotherapy in locally advanced rectal cancer. ( Bendahl, PO; Gunnlaugsson, A; Johnsson, A; Kjellén, E; Nilsson, P; Willner, J, 2007)
"Capecitabine was not resumed, and the rash resolved in 3 weeks with the use of pyridoxine and Udderly Smooth balm."5.33Hand-foot syndrome variant in a dihydropyrimidine dehydrogenase-deficient patient treated with capecitabine. ( Diasio, R; Elfiky, A; Saif, MW, 2006)
"5-Fluorouracil is an S-phase-specific, synthetic pyrimidine antimetabolite, which is used as a cytostatic agent for a variety of malignant lesions, either singly or in multidrug regimens."5.30Supraventricular arrhythmia: a complication of 5-fluorouracil therapy. ( Ahmad, M; Aziz, SA; Iqbal, K; Jalal, S; Mohi-ud-Din, K; Tramboo, NA, 1998)
" Of the 66 patients with colorectal carcinoma, 44 had not been previously treated with cytostatics and 22 were resistant to previous chemotherapy with 5-FU given either as a single agent or combined with other drugs."5.27Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil combined with high-dose folinic acid. An update. ( Chollet, P; Goldschmidt, E; Machover, D; Mathé, G; Misset, JL; Schwarzenberg, L; Vanden-Bulcke, JM, 1985)
"Sixteen patients with advanced colo-rectal cancer were treated with the combination methyl-CCNU, vincristin, 5-fluorouracil and streptozotocin (MOF-Strepto)."5.26[The combination methyl-CCNU, vincristine, 5-fluorouracil and streptozotocin in the treatment of advanced colo-rectal adenocarcinoma]. ( Cavalli, F; Sessa, C; Togni, P; Varini, M, 1982)
"This study examined the association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms and survival of patients with colorectal cancer (CRC) treated with 5-fluorouracil (5-FU)-based chemotherapy in Taiwan."5.24Polymorphisms of MTHFR C677T and A1298C associated with survival in patients with colorectal cancer treated with 5-fluorouracil-based chemotherapy. ( Chang, SN; Hsieh, LL; Lai, CY; Lin, YK; Sung, FC; Tang, R; Yeh, CC, 2017)
" This study was to compare the efficacy of TME with versus without preoperative concurrent chemoradiotherapy (CCRT) involving XELOX regimen (oxaliplatin plus capecitabine) in Chinese patients with stages II and III mid/low rectal adenocarcinoma."5.20Surgery with versus without preoperative concurrent chemoradiotherapy for mid/low rectal cancer: an interim analysis of a prospective, randomized trial. ( Chen, G; Ding, PR; Fan, WH; Gao, YH; Li, LR; Lu, ZH; Pan, ZZ; Wan, DS; Wang, FL; Wu, XJ; Zeng, ZF, 2015)
"In this multicentre, open-label, randomised, phase 3 study we randomly assigned patients with rectal adenocarcinoma, clinically staged as cT3-4 or any node-positive disease, to two groups: a control group receiving standard fluorouracil-based combined modality treatment, consisting of preoperative radiotherapy of 50·4 Gy in 28 fractions plus infusional fluorouracil (1000 mg/m(2) on days 1-5 and 29-33), followed by surgery and four cycles of bolus fluorouracil (500 mg/m(2) on days 1-5 and 29); or to an investigational group receiving preoperative radiotherapy of 50·4 Gy in 28 fractions plus infusional fluorouracil (250 mg/m(2) on days 1-14 and 22-35) and oxaliplatin (50 mg/m(2) on days 1, 8, 22, and 29), followed by surgery and eight cycles of oxaliplatin (100 mg/m(2) on days 1 and 15), leucovorin (400 mg/m(2) on days 1 and 15), and infusional fluorouracil (2400 mg/m(2) on days 1-2 and 15-16)."5.20Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial. ( Arnold, D; Fietkau, R; Folprecht, G; Ghadimi, M; Grabenbauer, GG; Graeven, U; Hoffmanns, H; Hofheinz, RD; Hohenberger, W; Hothorn, T; Lang-Welzenbach, M; Liersch, T; Lindemann, F; Raab, HR; Rödel, C; Sauer, R; Schlenska-Lange, A; Staib, L; Ströbel, P; Wilhelm, M; Wittekind, C; Wolff, HA, 2015)
"Ninety-nine consecutive patients with cT2-4N0-2M0 distal rectal adenocarcinoma were enrolled in a clinical trial (NCT00254683) and underwent baseline PET/CT followed by 54 Gy and 5-fluorouracil-based CRT."5.17Clinical relevance of positron emission tomography/computed tomography-positive inguinal nodes in rectal cancer after neoadjuvant chemoradiation. ( Bailão Aguilar, P; Buchpiguel, CA; Gama-Rodrigues, J; Habr-Gama, A; Lynn, P; Nahas, SC; Ono, CR; Perez, RO; Proscurshim, I; São Julião, GP, 2013)
"Patients with resectable, T3-4 and/or nodal involvement rectal adenocarcinoma were treated with oxaliplatin 60 mg/m(2) weekly and 5-fluorouracil 200 mg/m(2)/d infused continuously for five days, over a period of five weeks, and radiotherapy (45 Gy/25 fractions)."5.17Long-term results of preoperative 5-fluorouracil-oxaliplatin chemoradiation therapy in locally advanced rectal cancer. ( Anselmi, E; Ardizzoni, A; Bui, S; Camisa, R; Cascinu, S; Crafa, P; Dell'abate, P; Fontana, E; Galdy, S; Leonardi, F; Losardo, PL; Negri, FV; Pucci, F; Roncoroni, L, 2013)
"Patients with T2-T4/N+ rectal adenocarcinoma were randomly assigned to arm A-preoperative CRT with 5-fluorouracil (5-FU) continuous infusion followed by surgery-or arm B-induction oxaliplatin, folinic acid and 5-FU followed by CRT and surgery."5.16Short course chemotherapy followed by concomitant chemoradiotherapy and surgery in locally advanced rectal cancer: a randomized multicentric phase II study. ( Delaunoit, T; Demetter, P; Demols, A; Franchimont, D; Hendlisz, A; Maréchal, R; Peeters, M; Polus, M; Van de Stadt, J; Van Houtte, P; Van Laethem, JL; Verset, G; Vos, B, 2012)
"Between October 2006 and December 2009, 36 patients with non-metastatic rectal adenocarcinoma were treated with chemoradiotherapy of irinotecan (50 mg/m(2) weekly), 5-fluorouracil (250 mg/m(2) for 5 days/week) and pelvic radiation (45 Gy/1."5.16Combination of irinotecan and 5-fluorouracil with radiation in locally advanced rectal adenocarcinoma. ( El-Hadaad, HA; Roshdy, S; Wahba, HA, 2012)
"A regimen consisting of 5-fluorouracil/leucovorin plus oxaliplatin (FOLFOX-6) is widely used in France in the first-line treatment of metastatic colorectal cancer (MCRC)."5.15Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/leucovorin plus oxaliplatin (FOLFOX-6) as first-line treatment for metastatic colorectal cancer. ( Adenis, A; Bennouna, J; Bergougnoux, L; Conroy, T; Douillard, JY; Ducreux, M; Faroux, R; Hebbar, M; Kockler, L; Lledo, G; Rebischung, C; Ychou, M, 2011)
"Oxaliplatin combined with either fluorouracil/leucovorin (OXAFAFU) or capecitabine (OXXEL) has a demonstrated activity in metastatic colorectal cancer patients."5.14Randomised trial comparing biweekly oxaliplatin plus oral capecitabine versus oxaliplatin plus i.v. bolus fluorouracil/leucovorin in metastatic colorectal cancer patients: results of the Southern Italy Cooperative Oncology study 0401. ( Barberis, G; Cannone, M; Comella, P; Condemi, G; Farris, A; Filippelli, G; Maiorino, L; Massidda, B; Natale, D; Palmeri, S, 2009)
" Capecitabine (CAP) and oxaliplatin (OX) are synergistic with radiotherapy (RT) and active in colorectal neoplasms."5.14Neo-adjuvant treatment of rectal cancer with capecitabine and oxaliplatin in combination with radiotherapy: a phase II study. ( Bucci, L; Cannella, L; Carlomagno, C; D'Armiento, FP; D'Armiento, MR; De Placido, S; De Stefano, A; Farella, A; Pacelli, R; Pepe, S; Pesce, G; Solla, R, 2009)
"Consenting operable patients with stage II or III adenocarcinoma of the rectum received capecitabine (825 mg/m2 PO BID, 5 days/wk x 5 weeks) and SIB-IMRT delivering 55 Gy (2."5.13Preoperative capecitabine and accelerated intensity-modulated radiotherapy in locally advanced rectal cancer: a phase II trial. ( Ballonoff, A; Kane, M; Kavanagh, B; McCarter, M; Nash, R; Pearlman, N; Raben, D; Schefter, TE; Shah, RJ, 2008)
"This multicentre phase II study evaluated the efficacy and safety of preoperative capecitabine plus oxaliplatin and radiotherapy (RT) in patients with locally advanced rectal cancer (T3/T4 rectal adenocarcinoma with or without nodal involvement)."5.13Phase II study of capecitabine and oxaliplatin given prior to and concurrently with preoperative pelvic radiotherapy in patients with locally advanced rectal cancer. ( Bieri, G; Burkhard, R; Heitzmann, F; Hess, V; Koeberle, D; Neuweiler, J; Ruhstaller, T; Rust, C; Terraciano, L; Toepfer, M; von Moos, R; Winterhalder, R, 2008)
"Blood samples from 125 patients with primary adenocarcinoma of the mid-low rectum who received 5-fluorouracil-based chemotherapy and external beam radiotherapy (median dose 48."5.12A haplotype of the methylenetetrahydrofolate reductase gene predicts poor tumor response in rectal cancer patients receiving preoperative chemoradiation. ( Agostini, M; Ambrosi, A; Friso, ML; Leon, A; Lise, M; Lisi, V; Nitti, D; Pasetto, LM; Pucciarelli, S; Terrazzino, S, 2006)
"Patients with adenocarcinoma of the rectum stage >or=T3 or >or=N1 were treated with capecitabine 1330 mg/m per day in 2 divided doses days 1 to 42 and 50."5.12A phase II study of preoperative capecitabine and radiation therapy in patients with rectal cancer. ( Ben-Josef, E; Desai, SP; El-Rayes, BF; Greenson, JK; Griffith, KA; Huang, EH; Knol, JA; McGinn, CJ; Philip, PA; Zalupski, MM, 2007)
"Forty-two rectal carcinoma (T(3-4)N(0-2)M(0)) patients with grade 2 or 3 diarrhea refractory to loperamide were enrolled to receive octreotide."5.12Octreotide in the management of chemoradiotherapy-induced diarrhea refractory to loperamide in patients with rectal carcinoma. ( Karaoglu, A; Topkan, E, 2006)
"Seventy-two patients suffering from a metastatic colorectal cancer received, as first line treatment, a combination chronotherapy with 5-FU and folinic acid (infused from 10 pm to 10 am with a peak at 4 am, respectively at doses of 700 and 300 mg/m2 per day) and carboplatin (infused at the dose of 40 mg/m2 per day from 10 am to 10 pm with a peak at 4 pm)."5.11[Chronotherapy combining 5-fluorouracil, folinic acid and carboplatin as first line treatment in metastatic colorectal cancer. A phase 2 study]. ( Biquet, JF; David, A; Delforge, M; Focan, C; Focan-Henrard, D; Graas, MP; Kreutz, F; Longrée, L; Materne, R; Moeneclaey, N; Weerts, J, 2005)
"During adjuvant radiotherapy (RT) for rectal cancer, patients receiving 5-fluorouracil (5-FU) by protracted venous infusion have a higher risk of diarrhea than have patients receiving bolus 5-FU."5.10Acute diarrhea during adjuvant therapy for rectal cancer: a detailed analysis from a randomized intergroup trial. ( Cha, SS; Gunderson, LL; Haller, D; Macdonald, JS; Martenson, JA; Mayer, RJ; Miller, RC; O'Connell, MJ; Rich, TA; Sargent, DJ, 2002)
"The aim of this study was to determine whether the efficacy of the combination of 5-fluorouracil (5-FU), leucovorin (LV) and radiation therapy (RT) could be improved by the addition of interferon-alpha2b (IFN-alpha) in patients who have had a 'curative' resection, for rectal adenocarcinoma (Dukes' B2/C; T3 N0, T4 N0, N1-3)."5.10Surgical adjuvant therapy of rectal carcinoma: a controlled evaluation of leucovorin, 5-fluorouracil and radiation therapy with or without interferon-alpha2b. ( Andreadis, H; Androulakis, G; Batalis, T; Besbeas, S; Dardoufas, C; Gennatas, C; Hatzistylianos, G; Katsos, J; Komporozos, V; Legakis, N; Mallas, H; Mouratidou, D; Papadimitriou, J; Peros, G; Philippakis, M; Photopoulos, A; Pisiotis, C; Polymeneas, G; Pouli, A; Retalis, G; Samanidis, L; Smyrniotis, V; Stamatiadis, A; Tsavaris, N; Vasiliou, J; Voros, D, 2003)
"To evaluate the efficacy and safety of irinotecan as second-line treatment in patients with advanced colorectal cancer (ACC) failing or relapsing after 5-fluorouracil (5-FU) plus leucovorin (LV) standard chemotherapy."5.10Two different schedules of irinotecan (CPT-11) in patients with advanced colorectal carcinoma relapsing after a 5-fluorouracil and leucovorin combination. A randomized study. ( Dimitrakopoulos, A; Giannakakis, T; Gouveris, P; Karadima, D; Kosmas, C; Margaris, H; Papalambros, E; Papastratis, G; Polyzos, A; Rokana, S; Tsavaris, N; Tsipras, H; Vadiaka, M; Ziras, N, 2003)
"Thirty-two consecutive patients with a palpable adenocarcinoma of the rectum received preoperative RT (45 Gy in 25 fractions over 5 weeks) plus continuous chemotherapy with doxifluridine and leucovorin or 5-fluorouracil by continuous intravenous infusion during RT."5.10Preoperative chemoradiation in patients with resectable rectal cancer: results on tumor response. ( Andreola, S; Baratti, D; Bozzetti, F; Mariani, L; Spinelli, P; Stani, SC; Valvo, F, 2002)
"To assess the toxicity and the efficacy of preoperative radiotherapy with continuous infusion 5-fluorouracil (5-FU) for locally advanced adenocarcinoma of the rectum."5.09Early toxicity from preoperative radiotherapy with continuous infusion 5-fluorouracil for resectable adenocarcinoma of the rectum: a Phase II trial for the Trans-Tasman Radiation Oncology Group. ( Bell, A; Burmeister, BH; Fisher, R; Goldstein, D; Joseph, D; Kneebone, A; MacKay, JR; Ngan, SY; Rischin, D; Schache, DJ, 2001)
"Between 1966 and 1983 we selected 209 patients with colorectal adenocarcinomas, stage B (14%) and C (86%) of Dukes, treated with convenient surgery in 100% of cases, 5-fluorouracil in 85% and postoperative radiotherapy with telecobalt in 46."5.08[Is radiotherapy necessary in the control of colorectal cancer?]. ( Molina Esquivel, J; Rodríguez del Rincón, E; Vargas Sandoval, G; Velázquez López, J, 1995)
"The combination of radiation therapy with fluorouracil (5-FU)-based chemotherapy is generally accepted as appropriate postoperative therapy for patients with adenocarcinomas of the rectum that extend through the bowel wall or with lymph nodes positive for tumor."5.08Adjuvant postoperative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: initial results of intergroup 0114. ( Benson, AB; Cooke, E; Cummings, B; Gunderson, LL; Hollis, D; Macdonald, JS; Martenson, JA; O'Connell, MJ; Petroni, GR; Tepper, JE, 1997)
"The combination of pelvic radiotherapy and 5-fluorouracil-based chemotherapy is associated with an increase in acute gastrointestinal toxicity during rectal adjuvant therapy, most notably an increased incidence of diarrhea."5.08Acute treatment-related diarrhea during postoperative adjuvant therapy for high-risk rectal carcinoma. ( Kahn, MJ; Krook, JE; Martenson, JA; Miller, RC; Sargent, DJ, 1998)
"We have used a relatively new trial methodology, the group sequential design, to prospectively evaluate two dose levels of bolus/infusional 5-fluorouracil (5-FU) and folinic acid in 192 consecutive-patients with advanced colorectal carcinoma."5.08Bolus/infusional 5-fluorouracil and folinic acid. A report on two prospective, consecutive phase II studies with 5-fluorouracil dose escalation. ( Canney, PA; Cassidy, J; Habeshaw, T; Jodrell, DI; Mackean, MJ; McInnes, A; Paul, J; Reed, NS; Robertson, AG; Twelves, CJ; Yosef, H, 1998)
"Data from 12 metastatic colorectal cancer patients who were submitted to a pilot study with a multistep subcutaneous (sc) low dose recombinant interleukin-2 (rIL-2), 5-fluorouracil (5-FU) and leucovorin (LV) administration were compared with those from 13 historical controls who were comparable for the major prognostic indices."5.08A multistep therapy with subcutaneous low dose recombinant interleukin-2, 5-fluorouracil and leucovorin prolongs the response of metastatic colorectal cancer patients: a pilot study. ( Anselmi, L; Carpi, A; Ferrari, P; Nicolini, A; Sagripanti, A, 1998)
"To evaluate the contribution of semustine (MeCCNU) to adjuvant benefit, previously untreated patients with histologically proven adenocarcinoma of the rectum who had undergone curative resection were randomized to treatment with combination radiation therapy and fluorouracil (5-FU) followed by either 12 months of 5-FU and MeCCNU or 6 months of escalating 5-FU."5.07Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum. Gastrointestinal Tumor Study Group. ( , 1992)
"One hundred twenty-two chemotherapy-naive patients with histologically confirmed colorectal adenocarcinoma were entered into a randomized trial comparing infusional fluorouracil (FU) versus cisplatin (CDDP) and FU."5.06Randomized study of continuous infusion fluorouracil versus fluorouracil plus cisplatin in patients with metastatic colorectal cancer. ( Bosselli, B; Botet, J; Chapman, D; Cochran, C; Israel, K; Kemeny, N; Minsky, B; Niedzwiecki, D; Rosenbluth, R; Vinciguerra, V, 1990)
"Seventy-four previously untreated patients with metastatic colorectal adenocarcinoma were prospectively randomized into one of three treatment regimens: (1) 5-fluorouracil (5-FU) 450 mg/m2 as an intravenous (IV) bolus daily for five days or toxicity, then 200 mg/m2 IV bolus every other day for six doses; (2) methotrexate (MTX) 50 mg/m2 in normal saline by IV infusion over four hours followed by an IV bolus of 5-FU 600 mg/m2."5.06A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma. ( Burke, P; Creaven, P; Emrich, LJ; Herrera, L; Mittelman, A; Petrelli, N; Rustum, Y; Stulc, J, 1987)
"Seventy-seven patients with previously untreated, measurable, histologically confirmed, metastatic adenocarcinoma of the rectum or sigmoid were randomized to receive either epirubicin 90 mg/m2 (75 mg/m2 if prior radiotherapy) i."5.06A phase III randomized trial of epirubicin versus 5-fluorouracil in metastatic rectal/sigmoid adenocarcinoma. ( Blum, RH; Lafleur, F; Molinaro, P, 1989)
"In this prospective randomized study the effect of oral Ftorafur was compared with that of intravenous 5-fluorouracil in patients with advanced adenocarcinoma of the stomach, colon or rectum."5.06Comparison of oral ftorafur and intravenous 5-fluorouracil in patients with advanced cancer of the stomach, colon or rectum. ( Bjerkeset, T; Fjøsne, HE, 1986)
" Patients were stratified by the presence or absence of hepatic metastases and by performance status, and were subsequently randomized to receive fluorouracil (5-FU) (15 mg/kg/wk) alone or the same dose of 5-FU plus cisplatin (60 mg/m2 every 3 weeks)."5.06A prospective randomized trial of fluorouracil versus fluorouracil plus cisplatin in the treatment of metastatic colorectal cancer: a Hoosier Oncology Group trial. ( Ansari, R; Correa, J; Hui, S; Kubilis, P; Loehrer, PJ; Meyer, S; Stephens, D; Turner, S; Woodburn, R, 1988)
"Studies were analyzed to show the correlation of response with dose intensity of single-agent 5-fluorouracil (5-FU) against colorectal cancer, multiagent CMF (cyclophosphamide, methotrexate, 5-FU) regimens against advanced breast cancer, and adjuvant therapy in stage II breast cancer."5.06Applications of dose intensity to problems in chemotherapy of breast and colorectal cancer. ( Figueredo, A; Goodyear, M; Hryniuk, WM, 1987)
"We report the results of an expanded trial of 5-fluorouracil (5-FU) combined with high-dose folinic acid for treatment of patients with advanced colorectal or advanced gastric adenocarcinoma."5.06Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid. ( Chollet, P; Fourtillan, JB; Goldschmidt, E; Machover, D; Marquet, J; Metzger, G; Misset, JL; Schwarzenberg, L; Vandenbulcke, JM; Zittoun, J, 1986)
"Thirty-four patients with advanced adenocarcinoma of the gastrointestinal tract have been treated with high-dose 5-fluorouracil modulated by concomitant allopurinol therapy, in combination with either razoxane or adriamycin."5.05A trial of high-dose 5-fluorouracil with razoxane or adriamycin in the treatment of advanced adenocarcinoma of the gastrointestinal tract. ( Ashford, RF; Bakowski, M; Evans, M; Hellman, K; Jones, R; Lambert, J; Newton, K; Peters, N; Phillips, R; Smith, BJ, 1983)
"Because of biochemical and tissue culture evidence casting doubt on the physiologic relevance of reported synergy afforded by sequential administration of methotrexate (MTX) followed by 5-fluorouracil (5-FU), a randomized controlled clinical trial was conducted in 108 patients with advanced cancer, including 70 with squamous cell carcinoma (SCC) of the head and neck, nine with SCC of other primary sites, 24 with colorectal, and five with gastric adenocarcinomas."5.05Combination therapy with methotrexate and 5-fluorouracil: a prospective randomized clinical trial of order of administration. ( Coates, AS; Fox, RM; Hedley, D; Raghavan, D; Swanson, C; Tattersall, MH, 1984)
"In a randomized, multicenter study, 168 evaluable patients with colorectal adenocarcinoma at B2, C1 or C2 stages of the Dukes, Astler and Coller classification, were treated after radical surgery with BCG and 5-fluorouracil alone (regimen A) or in combination with hydroxyurea, methyl-CCNU and mitomycin C (regimen B)."5.05Preliminary research on the evaluation of some prognostic factors in a randomized study of adjuvant immunochemotherapy in colorectal adenocarcinoma. ( De Vecchis, L; Lagomarsino Caprino, MC; Mazzei, T; Periti, P; Popoli, P, 1984)
"To assess the effects of postoperative radiation therapy and chemotherapy on tumor recurrence and patient survival, 227 patients (data on 202 of whom were analyzed) who had undergone "curative" surgical resection for rectal adenocarcinoma were prospectively and randomly assigned to one of four treatments: no adjuvant therapy (concurrent controls, 58 patients), postoperative radiotherapy with 4000 or 4800 rad (50 patients), postoperative chemotherapy (fluorouracil and semustine [methyl-CCNU], 48 patients), or a combination of radiation therapy and chemotherapy (46 patients)."5.05Prolongation of the disease-free interval in surgically treated rectal carcinoma. ( , 1985)
"An adjuvant program of fluorouracil for patients undergoing "curative" resection for adenocarcinoma of the colon and rectum was initiated as a randomized clinical trial in January 1968."5.04Chemotherapy as an adjuvant to surgery for colorectal cancer. A follow-up report. ( Brown, PW; Horsley, JS; Lawrence, W; Romero, C; Terz, JJ, 1978)
"In a randomized multi-institutional trial of the Eastern Cooperative Oncology Group, 316 patients with advanced measurable colorectal adenocarcinoma were treated with a weekly schedule of 5-fluorouracil given orally and intravenously with oral-5-fluorouracil in combination with cyclophosphamide or 6-thioguanine, or with oral Methyl CCNU administered once every eight weeks."5.04Chemotherapy of advanced measurable colon and rectal carcinoma with oral 5-fluorouracil, alone or in combination with cyclophosphamide or 6-thioguanine, with intravenous 5-fluorouracil or beta-2'-deoxythioguanosine or with oral 3(4-methyl-cyclohexyl)-1(2- ( Carbone, P; Conroy, JF; Douglass, HO; Lavin, PT; Woll, J, 1978)
"A combined intraoperative and postoperative adjuvant program of 5 minus Fluorouracil (5 FU) for patients undergoing "curative" resection for adenocarcinoma of the colon and rectum was initiated as a randomized clinical trial in January 1968."5.04Chemotherapy as an adjuvant to surgery for colorectal cancer. ( Brown, PW; Donaldson, M; Horsley, S; Lawrence, W; Lovett, WL; Regelson, W; Ruffner, BW; Terz, JJ, 1975)
"In a randomized series of 70 patients with with colo rectal adenocarcinoma, a comparison of systemic 5-fluorouracil chemotherapy administered as a continuous 120-hours infusion vs."5.04Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma. ( Baker, LH; Reed, ML; Seifert, P; Vaitkevicius, VK, 1975)
" Here, we review the case of a 76-year-old male rectal cancer patient with liver metastasis who suffered extensive bowel necrosis after administration of 5-fluorouracil-based chemotherapy with bevacizumab, and required a subtotal colectomy and end-ileostomy."4.91Extensive bowel necrosis related to bevacizumab in metastatic rectal cancer patient: a case report and review of literature. ( Endo, K; Furukawa, J; Hoshino, Y; Ito, H; Kimata, M; Kobayashi, K; Masugi, Y; Ogata, Y; Shinozaki, H; Takada, S; Terauchi, T, 2015)
"5-Fluorouracil (5-FU) has been available for over 40 years and has been used in a wide variety of different regimens for the treatment of advanced colorectal cancer, a malignancy with a poor prognosis that is common in industrialized countries."4.80Which 5-fluorouracil regimen?--the great debate. ( Harper, P; Labianca, R; Vincent, M, 1999)
"To evaluate the safety and effectiveness of aflibercept in combination with fluorouracil, leucovorin, and irinotecan (FOLFIRI) in Korean patients with metastatic colorectal cancer (mCRC) who progressed with oxaliplatin-containing regimen."4.31Safety and effectiveness of aflibercept in combination with FOLFIRI in Korean patients with metastatic colorectal cancer who received oxaliplatin-containing regimen. ( Ahn, MS; Bae, BN; Baik, SH; Beom, SH; Han, SW; Jeon, SY; Jo, HJ; Kang, MH; Kim, DH; Kim, HK; Kim, JG; Kim, JH; Kim, JS; Kim, JY; Lee, MA; Lee, S; Oh, J; Park, I; Park, YS; Shin, SH; Yoon, JA; Zang, DY, 2023)
"Safety and effectiveness of aflibercept with 5-fluorouracil/levofolinate/irinotecan have not been reported in Japanese patients with metastatic colorectal cancer (mCRC) in a real-world clinical setting."4.31Aflibercept with FOLFIRI in Japanese patients with metastatic colorectal cancer: results of a post-marketing surveillance. ( Kazama, H; Terazawa, T; Uetake, H; Watanabe, J; Yamane, S; Yoshino, T, 2023)
"Using WES after a doublet chemotherapy regimen comprising irinotecan and 5-fluorouracil (n = 15), seven single nucleotide polymorphisms (SNPs) were identified as candidate biomarkers for irinotecan-associated toxicity of neutropenia."4.31Association between a single nucleotide polymorphism in the R3HCC1 gene and irinotecan toxicity. ( Hamamoto, Y; Hazama, S; Iida, M; Ioka, T; Kanesada, K; Matsui, H; Nagano, H; Ogihara, H; Shindo, Y; Suzuki, N; Takeda, S; Tokumitsu, Y; Tsunedomi, R; Yoshida, S, 2023)
"Adjuvant capecitabine monotherapy is an option for colon and upper rectum adenocarcinoma patients, providing they have stage II disease with an intermediate risk of recurrence, or stage III but they are above 70's or they have comorbidities."4.31Incidence of Disease Recurrence in Patients With Colon and Upper Rectum Adenocarcinoma Stage II and III Receiving Adjuvant Capecitabine Monotherapy: Do Number of Chemotherapy Cycles and Relative Dose Intensity of the Drug Play a Role? ( Aravantinos, G; Dessypris, N; Gkoura, S; Karampinos, K; Mauri, D; Miaris, N; Samantas, E; Sgouros, J; Spathas, N; Stamoulis, G; Theodoropoulos, I; Tzoudas, F; Visvikis, A, 2023)
" This case report discusses the clinical trial treatment of a patient with rectal adenocarcinoma by a new ropidoxuridine-capecitabine-radiotherapy combination."4.31A case report of typhlitis during novel use of ropidoxuridine-capecitabine-radiotherapy for treatment-naïve rectal cancer. ( Collins, JM; Kinsella, TJ; Kunos, CA; Piekarz, R, 2023)
"This retrospective study included 289 patients with metastatic colorectal cancer treated with second-line folinic acid, 5-fluorouracil, irinotecan, and vascular endothelial growth factor inhibitors."4.31Single-organ pulmonary metastasis is a favorable prognostic factor in metastatic colorectal cancer patients treated with FOLFIRI and vascular endothelial growth factor inhibitors. ( Chin, K; Fukuda, K; Fukuoka, S; Nakayama, I; Ogura, M; Ooki, A; Osumi, H; Shinozaki, E; Takahari, D; Wakatsuki, T; Yamaguchi, K; Yoshino, K, 2023)
"To assess the cost-effectiveness of cetuximab in combination with chemotherapy fluorouracil, oxaliplatin, and leucovorin (FOLFOX) or fluorouracil, irinotecan and leucovorin (FOLFIRI) compared to standard chemotherapy alone as a first-line treatment for metastatic colorectal cancer (mCRC) with positive KRAS wild type patients in Indonesia."4.31Cetuximab as first-line treatment for metastatic colorectal cancer (mCRC): a model-based economic evaluation in Indonesia setting. ( Armansyah, A; Khoe, LC; Megraini, A; Nadjib, M; Nugraha, RR; Permanasari, VY; Putri, S; Saldi, SRF; Santatiwongchai, B; Sastroasmoro, S; Setiawan, E, 2023)
"To evaluate the efficacy and safety of apatinib combined with FOLFIRI in the first-line treatment of advanced metastatic colorectal cancer (mCRC) and explore potential factors of efficacy."4.12Efficacy of apatinib combined with FOLFIRI in the first-line treatment of patients with metastatic colorectal cancer. ( Liu, H; Rong, X; Wang, J; Wang, Y; Yu, H; Zhao, J, 2022)
"To compare the efficacy and safety of folinic acid, fluorouracil and irinotecan (FOLFIRI) plus bevacizumab or aflibercept in metastatic colorectal cancer (mCRC) patients pretreated with oxaliplatin-based chemotherapy."4.12A Comparison of Folinic Acid, Fluorouracil and Irinotecan (FOLFIRI) plus Bevacizumab and FOLFIRI plus Aflibercept as Second-line Treatment for Metastatic Colorectal Cancer. ( Hong, JY; Jo, H; Kang, WK; Kim, H; Kim, ST; Lee, J; Lee, MS; Lee, YP; Lim, HY; Park, JO; Park, SH; Park, YS, 2022)
"The oral fluoropyrimidine S-1 has shown comparable efficacy to capecitabine in Asian and some Western studies on metastatic colorectal cancer."4.12Long-Term Safety Data on S-1 Administered After Previous Intolerance to Capecitabine-Containing Systemic Treatment for Metastatic Colorectal Cancer. ( Kwakman, JJM; Mol, L; Punt, CJA, 2022)
"Ocular toxicity derived from the use of systemic fluorouracil has been widely described in the literature, as well as the relationship between the use of capecitabine and the appearance of conjunctivitis."4.12Conjunctivitis associated with capecitabine treatment in a patient with colon cancer: The importance on educating patients into identifying adverse reactions. ( Bello Crespo, M; Gajete Pablos, MA; Gioseffi, HA; Roa García, DM; Trujillano Ruiz, A, 2022)
"Five-fluorouracil, folinic acid, oxaliplatin and irinotecan (FOLFOXIRI) regimen is used as the first-line treatment for metastatic colorectal cancer (mCRC)."4.12Safety and efficacy of irinotecan, oxaliplatin, and capecitabine (XELOXIRI) regimen with or without targeted drugs in patients with metastatic colorectal cancer: a retrospective cohort study. ( Gao, L; Liu, X; Ma, X; Ou, K; Wang, Q; Yang, L; Zhang, H, 2022)
"a capecitabine and oxaliplatin drug combination regimen has shown a survival benefit in patients with advanced colorectal cancer, yet its administration represents an attractive option for low resource settings."4.12Capecitabine plus oxaliplatin in the treatment of metastatic colorectal cancer at Tygerberg Hospital: a retrospective study. ( Begg, W; Kibudde, S, 2022)
"Female patients and patients aged sixty-five or older had an increased risk of developing severe diarrhea during preoperative chemoradiation therapy with capecitabine."4.02Relation between body composition and severe diarrhea in patients treated with preoperative chemoradiation with capecitabine for rectal cancer: a single-centre cohort study. ( Hartman, W; Nuyttens, JJME; Oomen-de Hoop, E; Rothbarth, J; van Meerten, E; van Rees, JM; van Vugt, JLA; Verhoef, C, 2021)
"The objective is to investigate whether thymidylate synthase gene TS 5'-UTR polymorphism of peripheral blood mononuclear cells are associated with clinical outcomes of patients with stage II-III rectal adenocarcinoma treated with adjuvant 5-fluorouracil (5-FU) chemotherapy in Chinese population."3.91Thymidylate synthase gene polymorphism predicts disease free survival in stage II-III rectal adenocarcinoma patients receiving adjuvant 5-FU-based chemotherapy. ( Chen, C; Li, S; Su, X; Wang, G; Xiao, H; Zhang, H, 2019)
" Interestingly, the panel also revealed that he had mismatch-repair(MMR)deficiency with MSH2 mutation, which is reported as a possible cause of resistance to 5-fluorouracil in colorectal cancer."3.88[A Case of Resistance to Systemic Therapy in Hypermutation of Colorectal Cancer]. ( Hotta, S; Ichikawa, H; Kameyama, H; Maruyama, S; Miura, K; Nagahashi, M; Nakano, M; Nogami, H; Shimada, Y; Tajima, Y; Takii, Y; Tanaka, K; Wakai, T; Yamada, S, 2018)
" Sixty-four patients (41%) treated with INCT-CRT and 57 CRT-CNCT patients (34%) experienced a grade 3+ adverse event (P = ."3.83Compliance and Toxicity of Total Neoadjuvant Therapy for Rectal Cancer: A Secondary Analysis of the OPRA Trial. ( Garcia-Aguilar, J; Kim, JK; Lin, ST; Omer, DM; Qin, LX; Saltz, LB; Thompson, HM; Valdivieso, SC; Verheij, FS; Wu, AJ; Yuval, JB, 2024)
"Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy."3.80Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation. ( Ayuso-Colella, JR; Bombí, JA; Burkholder, I; Castells, A; Conill, C; Cuatrecasas, M; Delgado, S; Feliz, L; Fernández-Esparrach, G; Gallego, R; García-Albéniz, X; Ginés, A; Hochhaus, A; Hofheinz, RD; María de Lacy, A; Maurel, J; Miquel, R; Pagés, M; Pereira, V; Pineda, E; Reig, O; Sosa, A; Victoria, I, 2014)
"When disseminated colorectal cancer is diagnosed the possibility of palliative chemotherapy should be conferred with an oncologist."3.79[Systemic palliative chemotherapy with 5-fluorouracil and leucovorin in disseminated colorectal cancer]. ( Raskov, HH; Wiboltt, K, 1999)
"Microsatellite instability (MSI) is a distinct molecular phenotype of colorectal cancer related to prognosis and tumour response to 5-fluorouracil (5-FU)-based chemotherapy."3.78The differential impact of microsatellite instability as a marker of prognosis and tumour response between colon cancer and rectal cancer. ( Cheon, JH; Hong, SP; Kim, H; Kim, NK; Kim, TI; Kim, WH; Min, BS, 2012)
"The patients with local advanced and metastatic colorectal cancer, receiving fluorouracil-based chemotherapy, and with an average plasma concentration of fluorouracil between 25 - 35 mg/L have a better prognosis, and lower incidence of adverse reactions such as bone marrow suppression, mucositis and diarrhea."3.78[Role of pharmacokinetic monitoring of serum fluorouracil concentration in patients with local advanced and metastatic colorectal cancer and further improving efficacy of fluorouracil-based chemotherapy]. ( Cai, X; Gu, HL; Hu, J; Song, WF; Wang, LW; Xue, P; Yang, HY, 2012)
"We describe an 80-year-old woman who presented with rectal bleeding and an increased INR due to the concomitant use of acenocoumarol and capecitabine for atrial fibrillation and metastatic cecal cancer, respectively."3.78[Increased INR from concomitant use of acenocoumarol and capecitabine]. ( Smorenburg, CH; Tomlow, B; Voll, ML, 2012)
" Two of the patients could not be treated with 5-FU any more because they had developed a myocardial ischemia, which was most likely caused by fluorouracil."3.785-FU-induced cardiac toxicity--an underestimated problem in radiooncology? ( Hautmann, MG; Kölbl, O; Steger, F, 2012)
"5-fluorouracil chemotherapy in patients with dihydropyrimidine dehydrogenase deficiency, can give rise to ocular and cutaneous toxicity."3.77A bilateral cicatricial ectropion and bilateral upper lid shortening caused by 5-fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency. ( Kemp, E; McDonald, A; Obi, EE, 2011)
"Over a period of 1 year in our hospital, 3 patients were diagnosed with 'ileitis following capecitabine use'."3.77[Ileitis following capecitabine use]. ( Bouma, G; Imholz, AL, 2011)
"The aim of this study was to investigate efficacy and toxicity of a modified 5-fluorouracil (5-FU), folinic acid, oxaliplatin (mFOLFOX-4) regimen followed by infusional 5-FU concomitant with radiotherapy for curatively resected stage III rectum adenocarcinoma patients."3.77Adjuvant modified FOLFOX-4 in patients with stage III rectum adenocarcinoma. ( Aksoy, S; Babacan, NA; Cihan, Ş; Odabaş, H; Öksüzoğlu, B; Özdemir, N; Uncu, D; Zengin, N, 2011)
"Failure rate of colorectal cancer after surgical resection remains around 50% and adjuvant treatments are clearly required."3.77Large scale trial for adjuvant treatment in high risk resected colorectal cancers. Rationale to test the combination of loco-regional and systemic chemotherapy and to compare l-leucovorin + 5-FU to levamisole + 5-FU. ( Nordlinger, B; Rougier, P, 1993)
"We examined the pre-treatment tumour biopsies (n=40) obtained from patients with rectal adenocarcinoma (clinical International Union Against Cancer stage ll/III) who were scheduled to receive neoadjuvant 5-fluorouracil-based chemoradiotherapy for EGFR, VEGF and HIF-1 expression by quantitative real-time polymerase chain reaction."3.76Gene expression profiles of epidermal growth factor receptor, vascular endothelial growth factor and hypoxia-inducible factor-1 with special reference to local responsiveness to neoadjuvant chemoradiotherapy and disease recurrence after rectal cancer surg ( Inoue, Y; Kusunoki, M; Miki, C; Okugawa, Y; Saigusa, S; Tanaka, K; Toiyama, Y; Yokoe, T, 2010)
"We investigated the efficacy and toxicity of metronomic capecitabine administered at a fixed dose of 1,000 mg daily in three elderly or poor performance status patients with advanced colorectal cancer (CRC) and gastric cancer."3.75To widen the setting of cancer patients who could benefit from metronomic capecitabine. ( Biasco, G; Brandi, G; Di Cicilia, R; Maleddu, A; Nannini, M; Nobili, E; Pantaleo, MA, 2009)
"A case of acute heart failure due to Takotsubo cardiomyopathy induced by 5-fluorouracil is described."3.75A case of Takotsubo cardiomyopathy during 5-fluorouracil treatment for rectal adenocarcinoma. ( Hata, N; Kobayashi, N; Mizuno, K; Shinada, T; Shirakabe, A; Yokoyama, S, 2009)
"One hundred and twenty-one MCRC patients with histologically proven adenocarcinoma and baseline ECOG performance status of < or =2 were treated with oxaplatin and (or) irinotecan-based chemotherapy regimens."3.75[Clinical significance of a transient increase in carcinoembryonic antigen and carbohydrate antigen 19-9 in patients with metastatic colorectal cancer receiving chemotherapy]. ( An, X; Feng, F; He, YJ; Jiang, WQ; Li, YH; Wang, FH; Wang, ZQ; Xiang, XJ; Xu, RH, 2009)
"Five-fluorouracil (5-FU) has become the standard chemotherapeutic agent for the treatment of advanced colorectal carcinoma."3.75An analysis of chemotherapy for colorectal carcinoma. ( Mittelman, A; Petrelli, NJ, 1984)
"Preoperative chemoradiation with 5-fluorouracil (5-FU) has improved local control and resectability in patients with locally advanced rectal adenocarcinoma."3.74Early clinical results from chemoradiation with 5-fluorouracil and oxaliplatin for locally advanced rectal cancer. ( Kauh, J; Koshy, M; Landry, J; Lawson, JD; Staley, C, 2008)
" When the total dose of 5-fluorouracil reached 21,200 mg and the total dose of oxaliplatin reached 880 mg after about 100 days of treatment, epiphora developed."3.74[Epiphora in a patient receiving FOLFOX therapy]. ( Iwagami, E; Niimi, M; Ono, Y; Tanaka, E; Uto, N; Yamato, M; Yatsuda, C, 2008)
"We present a case of hand-foot syndrome (HFS) induced by bolus 5-fluorouracil (5-FU) therapy."3.74[A case report of a patient with hand-foot syndrome induced by bolus 5-fluorouracil therapy]. ( Aoyagi, H; Enomoto, M; Higuchi, T; Iida, S; Ishikawa, T; Kobayashi, H; Matsuyama, T; Sugihara, K; Uetake, H; Yasuno, M, 2008)
"The aim of this study is to evaluate the safety and efficacy of hepatic artery infusion (HAI) of 5-fluorouracil (5FU) for patients with liver metastases from colorectal carcinoma after radiological placement of infusion catheters."3.74Outcomes of hepatic artery infusion therapy for hepatic metastases from colorectal carcinoma after radiological placement of infusion catheters. ( Hirayama, I; Horikoshi, H; Motegi, K; Saito, T; Sameshima, S; Sawada, T; Tomozawa, S, 2007)
"Headaches have been reported as a potential side effect of capecitabine therapy."3.74Capecitabine-induced headache responding to diltiazem. ( Fakih, MG; Raman, AK, 2007)
"The levels of both VEGF and PDGF-BB were measured in three time points, in the serum of 32 rectal carcinoma patients receiving daily reduced-dose/continuous capecitabine in combination with preoperative pelvic irradiation."3.74Daily low-dose/continuous capecitabine combined with neo-adjuvant irradiation reduces VEGF and PDGF-BB levels in rectal carcinoma patients. ( Be'ery, E; Fenig, E; Koren, C; Lavi, I; Loven, D; Shaked, Y; Sulkes, A; Yerushalmi, R, 2008)
"Formalin fixed, paraffin embedded pre-therapeutical tumor biopsies (n = 22) and post-therapeutical resection specimens (n = 40) from patients with rectal adenocarcinoma (clinical UICC stage II/III) receiving standardized neoadjuvant 5-fluorouracil (5-FU) based chemoradiotherapy were studied for Ki67 and p53 expression by immunohistochemistry and correlated with TS mRNA expression by quantitative TaqMan real-time PCR after laser microdissection."3.74Predictive value of Ki67 and p53 in locally advanced rectal cancer: correlation with thymidylate synthase and histopathological tumor regression after neoadjuvant 5-FU-based chemoradiotherapy. ( Aust, DE; Baretton, GB; Becker, H; Jakob, C; Liersch, T; Meyer, W, 2008)
"The study comprised 141 rectal adenocarcinoma patients who underwent preoperative radiotherapy with 5-fluorouracil (FU) based chemotherapy, followed by radical surgery."3.73Serum CEA as a predictor for the response to preoperative chemoradiation in rectal cancer. ( Baik, SH; Cho, CW; Kim, NK; Lee, KY; Park, YA; Seong, J; Sohn, SK, 2006)
"Forty patients with advanced adenocarcinoma of the rectum underwent preoperative chemoradiation on a prospective trial with irinotecan (50 mg/m2), 5-fluorouracil (225 mg/m2), and concomitant external-beam radiation (45-54 Gy) followed by complete surgical resection of the tumor with total mesorectal excision."3.72Longer time interval between completion of neoadjuvant chemoradiation and surgical resection does not improve downstaging of rectal carcinoma. ( Anné, PR; Fry, RD; Goldstein, SD; Isenberg, GA; Mahmoud, NN; Mitchell, E; Rose, DG; Stein, DE, 2003)
"One hundred and three patients with recurrent adenocarcinoma of the rectum underwent reirradiation with concurrent 5-fluorouracil-based chemotherapy."3.71Long-term results of reirradiation for patients with recurrent rectal carcinoma. ( Marks, G; Marks, J; Mohiuddin, M, 2002)
"A retrospective chart review was performed on 141 consecutive patients who received neoadjuvant chemoradiation (5-fluorouracil +/- cisplatin and 4,500-5,040 cGy) for biopsy-proven locally advanced adenocarcinoma of the rectum."3.71Neoadjuvant chemoradiation for rectal cancer: analysis of clinical outcomes from a 13-year institutional experience. ( Anscher, MS; Clary, B; Hartwig, M; Hurwitz, H; Jowell, P; Lee, C; Ludwig, K; Mantyh, C; McGrath, K; Morse, M; Noone, RB; Onaitis, MW; Pappas, TN; Seigler, HF; Tyler , DS, 2001)
"Sixteen patients with rectal adenocarcinoma up to 3 cm above the pectineal line with initial indications for abdominoperineal resection (APR) were submitted to a 5040-cGy (28 x 180 cGy) radiotherapy dose and chemotherapy during the first 3 and last 3 days of radiotherapy, using 425 mg/m2/day of 5-fluorouracil (5FU) and 20 mg/m2/day of folinic acid."3.70Radiation and chemotherapy instead of surgery for low infiltrative rectal adenocarcinoma: a prospective trial. ( Filho, WD; Lopes, A; Nakagawa, WT; Novaes, PE; Rossi, BM, 1998)
"During a 4-year period we treated 20 patients with locally advanced adenocarcinoma of the rectum using a protocol of preoperative simultaneous pelvic irradiation (4,030-6,040 cGy) and infusion chemotherapy (5-fluorouracil 100 mg/m2 per day over 96 hours and mitomycin 10 mg/m2) followed by surgical resection."3.70Combined preoperative radiation and mitomycin/5-fluorouracil treatment for locally advanced rectal adenocarcinoma. ( Burke, SJ; Knight, DC; Kwasnik, EM; Percarpio, BA, 1998)
"For almost 40 years, 5-fluorouracil (5-FU) has been the only useful drug with clinically meaningful activity in metastatic colorectal carcinoma."3.70Continuous infusion 5-fluorouracil as salvage chemotherapy in patients with advanced colorectal cancer. ( Au, E; Khoo, KS; Koo, WH; Lim, WT, 1999)
"Fifteen patients with rectal adenocarcinoma were endoscopically biopsied and given short-term [5 fluorouracil (5FU) (600 mg/m2) and Ca-Folinate (60 mg/m2) for two days] cytostatic therapy."3.70Changes in apoptotic and mitotic activity in rectal carcinoma after short-term cytostatic therapy as possible predictive factors. ( Benyó, I; Bodnár, Z; Farczádi, E; Kaszás, I; Szántó, J; Szende, B; Szlobodnyik, J, 1999)
"Adjuvant 5-fluorouracil (5-FU)-based chemotherapy is standard treatment for stage C colorectal cancer (CRC)."3.70Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy. ( Aaltonen, LA; Hemminki, A; Järvinen, H; Joensuu, H; Mecklin, JP, 2000)
"To report 5-fluorouracil in combination with folinic acid as a cause of severe nonischemic heart failure and to demonstrate the potential usefulness of an intra-aortic balloon pump."3.70Severe heart failure secondary to 5-fluorouracil and low-doses of folinic acid: usefulness of an intra-aortic balloon pump. ( David, JS; Gaussorgues, P; Gueugniaud, PY; Hepp, A; Petit, P, 2000)
"Thymidylate synthase (TS) expression in colorectal cancer metastases has been shown to predict for the clinical response to 5-fluorouracil."3.70Thymidylate synthase protein expression in primary colorectal cancer compared with the corresponding distant metastases and relationship with the clinical response to 5-fluorouracil. ( Aschele, C; Debernardis, D; Maley, F; Sobrero, A; Tunesi, G, 2000)
"Radiological and clinical evidence of acute necrosis in a meningioma following one cycle of chemotherapy with 5-fluorouracil, folinic acid, and levamisole was observed in a patient being treated for invasive rectal carcinoma."3.69Necrosis in a meningioma following systemic chemotherapy. Case report. ( Bernstein, M; Davidson, G; Erlichman, C; Villamil, A, 1994)
" The aim of this study was to define the toxicity (animal lethality) and the activity (growth delay assay, excision assay) of a bioreductive drug, tirapazamine, alone and combined with chemotherapy agents (5-FU, VP16, bleo, DTIC and c-DDP) on nude mice bearing xenografted human tumours: a rectal carcinoma (HRT18) and a melanoma (Na11+)."3.69The effect of tirapazamine (SR-4233) alone or combined with chemotherapeutic agents on xenografted human tumours. ( Guichard, M; Lartigau, E, 1996)
" In order to evaluate the HDRA with the 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide end point for clinical use, chemosensitivity to mitomycin C, doxorubicin, 5-fluorouracil, and cisplatin of 107 advanced gastric and 109 advanced colorectal cancers was determined in vitro in a correlative clinical trial."3.69Clinical applications of the histoculture drug response assay. ( Furukawa, T; Hoffman, RM; Kubota, T, 1995)
"A prospective trial was conducted involving 16 patients with colorectal adenocarcinoma using a regimen of continuous-infusion octreotide acetate (Sandostatin [octreotide acetate], Sandoz, East Hanover, NJ for the treatment of severe diarrhea induced by the weekly schedule of 5-fluorouracil (5-FU) in combination with leucovorin who were refractory to opiate therapy."3.68Bowel rest, intravenous hydration, and continuous high-dose infusion of octreotide acetate for the treatment of chemotherapy-induced diarrhea in patients with colorectal carcinoma. ( Creaven, P; Herrera, L; Petrelli, NJ; Rodriguez-Bigas, M; Rustum, Y, 1993)
" During a 12-month period seven patients with locally advanced adenocarcinoma of the rectum were treated preoperatively with simultaneous pelvic irradiation (4500-5040 cGy) and infusion chemotherapy (5-fluorouracil 1000 mg per m2 per day over 96 hours and mitomycin 10 mg per m2."3.68Combined modality preoperative therapy for unresectable rectal cancer. ( Alfano, F; Bitterman, J; Bowen, J; Percarpio, B; Ruszkowski, R; Sabbath, K, 1992)
"To determine if fluorouracil (5-FU) plus high-dose leucovorin (LV) enhances local response in patients receiving preoperative radiation therapy (RT) for adenocarcinoma of the rectum, we compared the degree of downstaging in patients receiving preoperative RT with or without chemotherapy."3.68Enhancement of radiation-induced downstaging of rectal cancer by fluorouracil and high-dose leucovorin chemotherapy. ( Cohen, AM; Enker, WE; Frankel, J; Kelsen, DP; Kemeny, N; Minsky, BD; Reichman, B; Saltz, L; Sigurdson, ER, 1992)
"Based on the in vitro and in vivo data suggesting synergistic cytolysis by the combination of 5-fluorouracil and interferon-gamma against a variety of malignant cell lines including a human colon carcinoma cell line (HT-29), we initiated studies in patients with advanced colon or rectal carcinoma."3.67Phase I and II studies of the combination of recombinant human interferon-gamma and 5-fluorouracil in patients with advanced colorectal carcinoma. ( Abbruzzese, JL; Ajani, JA; Edwards, C; Ende, K; Faintuch, JS; Gutterman, JU; Levin, B; Rios, AA; Saks, S, 1989)
"Twenty-one consecutive patients with primarily non-resectable adenocarcinoma of the rectum were treated with preoperative split-course radiotherapy (40 Gy) and simultaneous sequential methotrexate + 5-fluorouracil + leucovorin (MFL)."3.67Preoperative irradiation with and without chemotherapy (MFL) in the treatment of primarily non-resectable adenocarcinoma of the rectum. Results from two consecutive studies. ( Frykholm, G; Glimelius, B; Påhlman, L, 1989)
"Neoadjuvant therapy combining 5-fluorouracil, mitomycin C, and moderate-dose radiotherapy was given preoperatively to 29 patients with adenocarcinoma of the rectum, 3 patients with squamous cell cancer, and 1 patient with basaloid carcinoma of the anus."3.67Combined preoperative neoadjuvant radiotherapy and chemotherapy for anal and rectal cancer. ( Muff, NS; Shetabi, H; Smith, DE, 1986)
"Twenty-two patients with disseminated adenocarcinoma of the large bowel received therapy with 5-fluorouracil 800-1000 mg/m2 as a 24 h infusion for 4 consecutive days with 60 mg/m2 intravenous folinic acid administered every 6 hours."3.67Continuous infusion 5-fluorouracil and folinic acid in disseminated colorectal cancer. ( Higano, C; Mortimer, JE, 1988)
"Cardiac symptoms, including hypotension, developed in three patients with advanced colorectal carcinoma while being treated with cisplatin (CDDP) and 5-fluorouracil (5-FU)."3.67Hypotension as a manifestation of cardiotoxicity in three patients receiving cisplatin and 5-fluorouracil. ( Jakubowski, AA; Kemeny, N, 1988)
"Forty-four patients with locally recurrent or metastatic colorectal adenocarcinoma were treated with methotrexate (MTX) 100 mg/m2 i."3.67Sequential methotrexate, 5-fluorouracil, and calcium leucovorin in colorectal carcinoma. ( Anderson, T; Hansen, RM; Ritch, PS, 1986)
"Thirteen patients with metastatic colorectal adenocarcinoma underwent treatment with continuous ambulatory 5-fluorouracil (5-FU) infusion 300 mg/m2/day and intermittent bolus methotrexate (MTX) (200 mg/m2) with calcium leucovorin (LCV) 10 mg/m2 orally every 6 h X four to eight doses given 24 h after MTX."3.67Continuous 5-fluorouracil infusion and pulse methotrexate/leucovorin for colorectal adenocarcinoma. A report of excessive toxicity. ( Anderson, T; Frick, J; Hansen, RM; Quebbeman, EJ; Ritch, PS, 1987)
"We report the results of an expanded trial of 5-fluorouracil (FUra) combined with high-dose folinic acid for treatment of patients with advanced colorectal or gastric adenocarcinoma."3.67Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid. ( Benavides, M; Chollet, P; Goldschmidt, E; Machover, D; Marquet, J; Metzger, G; Misset, JL; Schwarzenberg, L; Vandenbulcke, JM; Zittoun, J, 1987)
"To delineate the efficacy of continuous intravenous 5-fluorouracil (5-FU) infusion therapy for advanced colorectal adenocarcinoma, a study of 36 patients with measurable metastatic disease was conducted."3.67Long-term ambulatory treatment of metastatic colorectal adenocarcinoma by continuous intravenous infusion of 5-fluorouracil. ( Ausman, R; Becker, T; Blake, D; Caballero, G; Hansen, R; Jenkins, D; Quebbeman, E; Ritch, P; Schulte, W; Tangen, L, 1985)
"Twenty-eight patients with advanced adenocarcinoma were treated with a combination of thymidine, 5-FU, and PALA."3.67Phase I-II clinical trial of thymidine, 5-FU, and PALA given in combination. ( Bedikian, A; Bodey, GP; Chiuten, DF; Freireich, EJ; Valdivieso, M, 1985)
"Thirty-eight patients with advanced colorectal adenocarcinoma were treated with the following regimen: N5-10-methyltetrahydrofolate (MTHF) (200 mg/m2/day) and 5-fluorouracil (5-FU) (375 mg/m2/day) given concomitantly, consecutively for 5 days, every 4 weeks, in order to evaluate the potential advantage derived from the biochemical enhancement of cytotoxic activity of 5-FU by high-dose reduced folates."3.67Phase II study with high-dose N5-10-methyltetrahydrofolate and 5-fluorouracil in advanced colorectal cancer. ( Bruzzone, M; Nobile, MT; Rosso, R; Rubagotti, A; Sertoli, MR; Tagarelli, G, 1985)
"The action of floxuridine depends greatly on its concentration for treatment of liver metastases of colorectal carcinomas and other tumors."3.66[Completely implantable infusion pump. A new therapeutic possibility for selected patients with liver tumors]. ( Balch, CM; Urist, MM, 1983)
"A total of 65 patients with advanced colorectal or breast cancer were given oral tegafur in the phase I study."3.66Phase I-II studies of oral tegafur (ftorafur). ( Ansfield, FJ; Kallas, GJ; Singson, JP, 1983)
"A 72 year old man with rectal adenocarcinoma developed chronic renal failure when treated by surgery and subsequent chemotherapy (5-fluorouracil, Mitomycin C and Cytosine arabinoside) and immunotherapy."3.66Severe glomerular mesangiolysis in a patient with rectal adenocarcinoma treated with cytotoxic drugs. ( Fornari, G; Mazzucco, G; Monga, G, 1982)
"Consecutive studies were undertaken in advanced colorectal adenocarcinoma, comparing two different schedules of the combination methyl-CCNU, 6-thioguanine, and 5-fluorouracil in 89 patients."3.66Methyl-CCNU, 6-thioguanine, and 5-fluorouracil in advanced colorectal cancer. ( Aroney, RS; Bell, DR; Chan, WK; Dalley, DN; Levi, JA, 1981)
"The modulation of 5-fluorouracil (FUra) metabolism by methotrexate (MTX) pretreatment in monolayer cultures of human colorectal adenocarcinoma."3.66Modulation of 5-fluorouracil metabolism and cytotoxicity by antimetabolite pretreatment in human colorectal adenocarcinoma HCT-8. ( Benz, C; Cadman, E, 1981)
"Fifty-four patients with clinical evidence of residual colorectal adenocarcinoma following surgical removal of the primary tumor were treated with a combination of 5-fluorouracil, mitomycin C, adriamycin, and cytosine arabinoside."3.66Chemotherapy for colorectal cancer with a combination of 5-fluorouracil, mitomycin C, adriamycin, and cytosine arabinoside: a pilot study. ( Davis, S; Park, YK, 1978)
" 5-Fluorouracil (5 FU) is the first chemotherapeutic agent found to have a significant effect on gastrointestinal adenocarcinoma."3.64PALLIATIVE MANAGEMENT OF GASTROINTESTINAL CANCER. ( HART, GD, 1964)
"In metastatic colorectal cancer (mCRC), ETS gains relevance as an early available surrogate for patient survival."3.30Standard diametric versus volumetric early tumor shrinkage as a predictor of survival in metastatic colorectal cancer: subgroup findings of the randomized, open-label phase III trial FIRE-3 / AIO KRK-0306. ( D'Anastasi, M; Decker, T; Gesenhues, AB; Heinemann, V; Heintges, T; Hesse, N; Hofmann, FO; Holch, JW; Kahl, C; Kaiser, F; Kiani, A; Kullmann, F; Link, H; Modest, DP; Moehler, M; Scheithauer, W; Stintzing, S; von Weikersthal, LF, 2023)
"In metastatic colorectal cancer (mCRC), the role of Trop-2 and Nectin-4 has been poorly investigated."3.30Trop-2 and Nectin-4 immunohistochemical expression in metastatic colorectal cancer: searching for the right population for drugs' development. ( Bergamo, F; Conca, V; Cremolini, C; Di Donato, S; Fanotto, V; Fontanini, G; Germani, MM; Giordano, M; Latiano, TP; Lonardi, S; Masi, G; Moretto, R; Niccoli, C; Passardi, A; Pietrantonio, F; Prisciandaro, M; Proietti, A; Tamburini, E; Ugolini, C; Zaniboni, A, 2023)
"Standard treatment of locally advanced rectal cancer (LARC) was neoadjuvant chemoradiotherapy (CRT), followed by total mesorectal excision (TME)."3.30Total neoadjuvant treatment to increase the clinical complete response rate for distal locally advanced rectal cancer (TESS): A study protocol of a prospective, open-label, multicenter, single-arm, phase 2 trial. ( Bai, S; Cai, P; Chang, H; Chen, G; Gao, Y; Liu, S; Luo, H; Pan, Z; Wang, Q; Wang, X; Wu, X; Xiao, W; Ye, Y; Yu, H; Zeng, Z; Zhuang, Y, 2023)
"For patients with locally advanced rectal cancer choosing between neoadjuvant FOLFOX and 5FUCRT, the distinctive PRO profiles inform treatment selection and shared decision making."3.30Patient-Reported Outcomes During and After Treatment for Locally Advanced Rectal Cancer in the PROSPECT Trial (Alliance N1048). ( Basch, E; Chang, G; Colgrove, B; Denicoff, A; Dueck, AC; Farma, J; George, T; Ginos, B; Gollub, M; Mamon, H; Mazza, GL; Meyerhardt, JA; Minasian, L; Mitchell, SA; Musher, B; O'Reilly, E; Rogak, L; Saltz, L; Schrag, D; Shi, Q; Thanarajasingam, G; Venook, A; Weiser, M, 2023)
"Adults with rectal cancer that had been clinically staged as T2 node-positive, T3 node-negative, or T3 node-positive who were candidates for sphincter-sparing surgery were eligible to participate."3.30Preoperative Treatment of Locally Advanced Rectal Cancer. ( Al Baghdadi, T; Basch, E; Chang, GJ; Colgrove, B; Dueck, AC; Farma, JM; George, TJ; Goldberg, J; Gollub, MJ; Goodman, KA; Gordon, V; Kennecke, HF; Mamon, HJ; McWilliams, RR; Meyerhardt, JA; Montemurro, M; Musher, BL; Nelson, GD; O'Reilly, EM; Saltz, LB; Schrag, D; Shergill, A; Shi, Q; Venook, AP; Weiser, MR, 2023)
"In clinical trials, the assessment of safety is traditionally focused on the overall rate of high-grade and serious adverse events (AEs)."3.30Adverse events during first-line treatments for mCRC: The Toxicity over Time (ToxT) analysis of three randomised trials. ( Boccaccino, A; Bustreo, S; Carullo, M; Clavarezza, M; Cremolini, C; Cupini, S; Daniel, F; Libertini, M; Lonardi, S; Morano, F; Niger, M; Palermo, F; Pietrantonio, F; Procaccio, L; Raimondi, A; Rossini, D; Santini, D; Tomasello, G; Zaniboni, A, 2023)
"The prognosis of mCRC (metastatic colorectal cancer) patients with RAS mutation is poor and capecitabine and oxaliplatin (CapeOx) plus bevacizumab has shown to be one of the standard therapeutic regimens as first line for these patients with objective response rate (ORR) of ~ 50% and median progression-free survival (mPFS) of 8-9 months."3.30Sintilimab plus bevacizumab and CapeOx (BBCAPX) on first-line treatment in patients with RAS mutant, microsatellite stable, metastatic colorectal cancer: study protocol of a randomized, open-label, multicentric study. ( Ding, K; Dong, C; Fang, X; Hu, H; Li, J; Liao, X; Sun, L; Wang, J; Weng, S; Xiao, Q; Xu, D; Yuan, Y; Zhang, S; Zhong, C, 2023)
" Patient characteristics were evaluated with multiple regression analyses for survival outcomes, using the Cox proportional hazard model and linear regression analyses for the worst grade of adverse events."3.11Impact of chronological age on efficacy and safety of fluoropyrimidine plus bevacizumab in older non-frail patients with metastatic colorectal cancer: a combined analysis of individual data from two phase II studies of patients aged >75 years. ( Amagai, K; Bando, Y; Denda, T; Endo, S; Hatachi, Y; Hyodo, I; Ikezawa, K; Ishida, H; Kobayashi, K; Kuramochi, H; Morimoto, M; Moriwaki, T; Nakajima, G; Negoro, Y; Nishina, T; Sakai, Y; Sato, M; Shimada, M; Tsuji, A; Yamamoto, Y, 2022)
"Fecal incontinence was high after sphincter preservation."3.11Quality of life in a randomized trial comparing two neoadjuvant regimens for locally advanced rectal cancer-INCAGI004. ( Araujo, RO; Ferreira, CG; Guaraldi, S; Linhares, E; Martins, I; Thuler, LC; Torres, C; Valadão, M; Victorino, AP; Vieira, FM, 2022)
"This multicenter single-arm, phase II study evaluated the efficacy and safety of uninterrupted panitumumab usage combined with cytotoxic doublets for unresectable/metastatic colorectal cancer (mCRC)."3.11Multicenter, single-arm, phase II study of the continuous use of panitumumab in combination with FOLFIRI after FOLFOX for RAS wild-type metastatic colorectal cancer: Exploratory sequential examination of acquired mutations in circulating cell-free DNA. ( Akazawa, N; Ando, T; Hirata, K; Kagawa, Y; Kato, T; Maeda, H; Mishima, H; Nagasaka, T; Nagata, N; Oba, K; Sakamoto, J; Shiozawa, M; Watanabe, J; Yamada, T; Yokota, M, 2022)
"Locally advanced rectal cancer (LARC) is an area of unmet medical need with one third of patients dying from their disease."3.11Population pharmacokinetic analyses of regorafenib and capecitabine in patients with locally advanced rectal cancer (SAKK 41/16 RECAP). ( Bärtschi, D; Bastian, S; Bovet, C; Csajka, C; Decosterd, LA; Guckenberger, M; Jaehde, U; Joerger, M; Largiadèr, CR; Prost, JC; Schmulenson, E; Theurillat, R; von Moos, R, 2022)
"The treatment of colorectal cancer (CRC) has evolved and become more personalized during the past several years."3.01Chemotherapy Duration for Various Indications in Colorectal Cancer: a Review. ( Damato, A; Dottorini, L; Ghidini, A; Ghidini, M; Iaculli, A; Luciani, A; Petrelli, F; Tomasello, G, 2023)
"The meta-analysis aimed to assess the clinical efficacy of chemotherapeutic triplet-drug regimen combined with anti-EGFR antibody in patients with initially unresectable metastatic colorectal cancer (mCRC)."3.01Triplet-drug chemotherapy combined with anti-EGFR antibody as an effective therapy for patients with initially unresectable metastatic colorectal cancer: a meta-analysis. ( Dong, W; Jiang, T; Jiang, X; Li, H; Li, Y; Lv, Y; Tian, M; Xiao, J; Yin, Z; Zeng, J, 2023)
"Overall, our results showed that preCRT was feasible and safe in older patients with rectal cancer who were evaluated as fit based on CGA, supporting the use of CGA to tailor oncological treatment and predict the tolerance of a specific therapy."3.01Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric assessment: A planned interim analysis of a multicenter, phase II trial. ( Chen, B; Cheng, YJ; Fang, H; Jin, J; Li, N; Li, YX; Liang, JW; Liu, WY; Liu, YP; Liu, Z; Lu, NN; Pei, W; Qi, SN; Song, YW; Tang, Y; Wang, J; Wang, SL; Wang, XS; Yang, L; Zhang, HZ; Zhou, HT; Zhou, ZX, 2021)
"Both LRC and DFS of rectal cancer patients treated with HART vs."3.01Tumor regression grading after preoperative hyperfractionated radiotherapy/chemoradiotherapy for locally advanced rectal cancers: interim analysis of phase III clinical study. ( Dębosz-Suwińska, I; Galwas-Kliber, K; Idasiak, A; Mrochem-Kwarciak, J; Rajczykowski, M; Stobiecka, E; Suwiński, R; Zeman, M, 2021)
"Hyperthermia was defined as feasible if 70% of patients received at least eight treatments."3.01Deep regional hyperthermia with preoperative radiochemotherapy in locally advanced rectal cancer, a prospective phase II trial. ( Bitzer, M; Fend, F; Gani, C; Gellermann, J; Heinrich, V; Königsrainer, A; Lamprecht, U; Moll, M; Wenz, S; Ziegler, A; Zips, D, 2021)
"4 Gy) with or without intravenous pembrolizumab administered at a dosage of 200 mg every 3 weeks for up to 6 doses before surgery."3.01Use of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: Initial Results From the Pembrolizumab Arm of a Phase 2 Randomized Clinical Trial. ( Colangelo, LH; Faller, BA; George, S; George, TJ; Gollub, MJ; Hall, WA; Hong, TS; Jacobs, SA; Kachnic, LA; Kainthla, R; Lucas, PC; O'Rourke, MA; Parker, W; Rahma, OE; Russell, MM; Schefter, TE; Sigurdson, E; Stella, PJ; Valicenti, RK; Vijayvergia, N; Wolmark, N; Yothers, G; You, YN, 2021)
"Radiation proctitis was identified by imaging in 9 (15."2.94Effect of interval between preoperative radiotherapy and surgery on clinical outcome and radiation proctitis in rectal cancer from FOWARC trial. ( Cheng, YK; Gao, X; Huang, XY; Lan, P; Ma, TH; Qin, QY; Wang, L, 2020)
"Patients with stage II/III rectal cancer who had completed neoadjuvant 5-fluorouracil-based chemoradiation and had undergone complete resection were enrolled."2.94Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil, and Leucovorin Versus Oxaliplatin, 5-Fluorouracil, Leucovorin, and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Preoperative Chemoradiation: A Tri ( Atkins, JN; Awan, RA; Benson, AB; Brierley, JD; Catalano, P; Catalano, RB; Cella, D; Chakravarthy, AB; Cripps, C; Diasio, RB; Flynn, PJ; Giantonio, BJ; Haller, DG; Hamilton, SR; Leichman, CG; Meropol, NJ; Mitchell, EP; Mulcahy, MF; O'Brien, TE; O'Dwyer, PJ; Petrelli, NJ; Santala, R; Sigurdson, ER; Sinicrope, FA; Sloan, J; Tepper, JE; Wagner, LI; Weis, JR; Zhao, F, 2020)
"High-risk rectal cancer patients were randomized to SCRT followed by chemotherapy (6 cycles CAPOX or alternatively 9 cycles FOLFOX4) and subsequent surgery, or long-course radiotherapy (25-28 × 2-1."2.94Compliance and tolerability of short-course radiotherapy followed by preoperative chemotherapy and surgery for high-risk rectal cancer - Results of the international randomized RAPIDO-trial. ( Bahadoer, RR; Capdevila, J; Cervantes, AMR; de Groot, DJA; Dijkstra, EA; Edhemovic, I; Fokstuen, T; Glimelius, B; Hendriks, MP; Hilling, DE; Hospers, GAP; Kranenbarg, EM; Marijnen, CAM; Nilsson, PJ; Putter, H; Roodvoets, AGH; Ten Tije, AJ; van de Velde, CJH; van der Valk, MJM; van Etten, B, 2020)
"Patients with locally advanced rectal cancer will be randomized to receive PCRT followed by TME and adjuvant chemotherapy (arm A) or upfront radical surgery with TME followed by adjuvant FOLFOX chemotherapy (arm B)."2.94Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label, multicenter, phase II randomized controlled trial. ( Ahn, JB; Baek, JH; Beom, SH; Chang, JS; Hur, H; Jeong, SY; Jung, I; Kim, HS; Kim, NK; Kim, SH; Kim, TI; Koom, WS; Lee, JB; Lee, KY; Lim, JS; Min, BS; Park, S; Shin, SJ, 2020)
"KRAS wild-type clinical stage III rectal cancer patients were enrolled."2.94A prospective, single-arm, multicenter trial of neoadjuvant chemotherapy with mFOLFOX6 plus panitumumab without radiotherapy for locally advanced rectal cancer. ( Endo, I; Ishibe, A; Kunisaki, C; Nakagawa, K; Ota, M; Suwa, H; Suwa, Y; Toritani, K; Watanabe, J; Yamanaka, T, 2020)
"Patients with locally advanced rectal cancers might benefit from treatment in specialized high-volume hospitals."2.94The long-term influence of hospital and surgeon volume on local control and survival in the randomized German Rectal Cancer Trial CAO/ARO/AIO-94. ( Beißbarth, T; Fietkau, R; Ghadimi, M; Hohenberger, W; Raab, HR; Rödel, C; Sauer, R; Sprenger, T; Staib, L; Tschmelitsch, J, 2020)
" Adverse event data collection is recorded at every visit."2.94Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma. ( Al Awabdeh, T; Al Darazi, M; Al Masri, M; Alqasem, K; Amarin, R; Charafeddine, M; Dabous, A; Daoud, F; Deeba, S; El Husseini, Z; Elkhaldi, M; Geara, F; Hushki, A; Jaber, O; Jamali, F; Kattan, J; Khalifeh, I; Kreidieh, M; Mohamad, I; Mukherji, D; Shamseddine, A; Temraz, S; Turfa, R; Zeidan, YH, 2020)
"Patients affected with Stage IV colorectal cancer and unresectable metastases represent a heterogeneous group."2.90Resection or Stenting in the Treatment of Symptomatic Advanced Metastatic Rectal Cancer: A Dilemma. ( Crocetti, D; DE Felice, F; DE Toma, G; Fiori, E; Lamazza, A; Mingoli, A; Sapienza, P; Sterpetti, AV; Tarallo, M, 2019)
"More than half of the 40,000 incident rectal cancer patients in the United States each year are diagnosed at clinical stage II and III (locally advanced stage)."2.90Challenges and solutions in the design and execution of the PROSPECT Phase II/III neoadjuvant rectal cancer trial (NCCTG N1048/Alliance). ( Basch, E; Gollub, M; Mamon, H; Saltz, L; Schrag, D; Shi, Q; Venook, A; Weiser, M, 2019)
"A radical rectal cancer surgery was performed 6 to 8 weeks after the simultaneous chemoradiotherapy."2.90Preoperative Volumetric Modulated Arc Therapy With Simultaneous Integrated Boost for Locally Advanced Distal Rectal Cancer. ( Chen, J; Dai, G; Du, X; Feng, L; Jia, B; Liu, H; Liu, Q; Wang, Y; Wen, K; Yang, Y; Zeng, M; Zhu, Y, 2019)
" We included patients with rectal cancer who received 4 courses of modified FOLFOX6 (mFOLFOX6) before rectal surgery and examined the postoperative complication rate, the clinicopathological response, and the rate of chemotherapy-related adverse events (UMIN 000012559)."2.90Preoperative FOLFOX in resectable locally advanced rectal cancer can be a safe and promising strategy: the R-NAC-01 study. ( Funakoshi, T; Hattori, M; Hirose, K; Homma, S; Ichikawa, N; Iijima, H; Ishikawa, T; Ishizu, H; Kamiizumi, Y; Kawamata, F; Koike, M; Kon, H; Kuraya, D; Minagawa, N; Murata, R; Nomura, M; Ohno, Y; Omori, K; Sato, M; Takahashi, N; Takeda, K; Taketomi, A; Yokota, R; Yoshida, T, 2019)
"Peripheral blood leukocytosis and neutrophilia reflect cancer inflammation and have been proposed as prognostic immunological biomarkers in various malignancies."2.90Leukocytosis and neutrophilia as independent prognostic immunological biomarkers for clinical outcome in the CAO/ARO/AIO-04 randomized phase 3 rectal cancer trial. ( Arnold, D; Beißbarth, T; Diefenhardt, M; Fietkau, R; Fokas, E; Folprecht, G; Ghadimi, M; Grabenbauer, GG; Graeven, U; Grützmann, R; Hartmann, A; Hofheinz, RD; Liersch, T; Martin, D; Rieger, M; Rödel, C; Rödel, F; Ströbel, P; von der Grün, J; Weitz, J, 2019)
"Patients with cT4 or fixed cT3 rectal cancer were randomized either to preoperative 5 × 5 Gy and three cycles of FOLFOX4 or to chemoradiation (50."2.90Long-course preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for clinical T4 and fixed clinical T3 rectal cancer: long-term results of the randomized Polish II study. ( Bębenek, M; Bujko, K; Cencelewicz, A; Ciseł, B; Jankiewicz, M; Jankowski, M; Kapturkiewicz, B; Kapuściński, W; Kępka, L; Kosakowska, E; Kładny, J; Las-Jankowska, M; Maciejczyk, A; Majewski, A; Markiewicz, W; Michalski, W; Pietrzak, L; Polkowski, W; Rutkowski, A; Sadowski, J; Socha, J; Spałek, M; Styliński, R; Suwiński, R; Toczko, Z; Wasilewska-Tesluk, E; Wyrwicz, L; Zegarski, W; Żelazowska-Omiotek, U; Zygulska, J, 2019)
"9%) in arm B experienced grade 3/4 adverse events related to bevacizumab; the most frequent were 2 anastomotic fistulas (both in arm A) and abscesses (1 in arm A and 2 in arm B)."2.90Efficacy and Safety of Two Neoadjuvant Strategies With Bevacizumab in MRI-Defined Locally Advanced T3 Resectable Rectal Cancer: Final Results of a Randomized, Noncomparative Phase 2 INOVA Study. ( Adenis, A; André, T; Azria, D; Bachet, JB; Balosso, J; Ben Abdelghani, M; Borg, C; Boudghène, F; Conroy, T; Coudert, M; François, Y; Ghiringhelli, F; Ionescu-Goga, M; Lakkis, Z; Mantion, G; Mornex, F; Quero, L; Rio, E; Roullet, B; Spaëth, D; Tanang, A; Vendrely, V, 2019)
"This study investigated the role of hyperthermia combined with preoperative concurrent chemoradiotherapy (CCRT) for locally advanced rectal cancer (LARC) according to hypoxic marker expression."2.87Selecting patients for hyperthermia combined with preoperative chemoradiotherapy for locally advanced rectal cancer. ( Gu, MJ; Kang, MK; Kim, JH; Kim, SW; Yea, JW, 2018)
" The objective of this study was to compare outcome measures, adverse effects, and cost of FOLFOX4 and FOLFIRINOX treatments in rectal cancer patients."2.87Comparisons of Efficacy, Safety, and Cost of Chemotherapy Regimens FOLFOX4 and FOLFIRINOX in Rectal Cancer: A Randomized, Multicenter Study. ( Chen, Y; Liu, J; Qi, F; Yan, Q; Zhang, G; Zheng, Z, 2018)
"Surrogate end points in rectal cancer after preoperative chemoradiation are lacking as their statistical validation poses major challenges, including confirmation based on large phase III trials."2.87Neoadjuvant rectal score as individual-level surrogate for disease-free survival in rectal cancer in the CAO/ARO/AIO-04 randomized phase III trial. ( Fietkau, R; Fokas, E; Ghadimi, M; Grabenbauer, GG; Graeven, U; Grützmann, R; Hartmann, A; Hofheinz, RD; Hohenberger, W; Hothorn, T; Kaufmann, M; Köhne, CH; Liersch, T; Rödel, C; Sauer, R; Ströbel, P; Wittekind, C, 2018)
"The German rectal cancer trial CAO/ARO/AIO-04 has shown a significant benefit in 3-year disease-free survival (DFS) of adding oxaliplatin to a standard preoperative 5-fluorouracil (5-FU)-based chemoradiotherapy (CRT) and adjuvant chemotherapy in patients with locally advanced rectal cancer."2.87Impact of age on the efficacy of oxaliplatin in the preoperative chemoradiotherapy and adjuvant chemotherapy of rectal cancer: a post hoc analysis of the CAO/ARO/AIO-04 phase III trial. ( Arnold, D; Fietkau, R; Fokas, E; Folprecht, G; Ghadimi, M; Grabenbauer, GG; Graeven, U; Hofheinz, RD; Hohenberger, W; Hothorn, T; Kaufmann, M; Liersch, T; Rödel, C; Sauer, R, 2018)
"To compare acute adverse events (AE) and postoperative complication rates in a randomized trial of short-course (SC) versus long-course (LC) preoperative radiotherapy."2.84Acute Adverse Events and Postoperative Complications in a Randomized Trial of Preoperative Short-course Radiotherapy Versus Long-course Chemoradiotherapy for T3 Adenocarcinoma of the Rectum: Trans-Tasman Radiation Oncology Group Trial (TROG 01.04). ( Ackland, S; Ansari, N; Burmeister, B; Fisher, RJ; Heriot, A; Joseph, D; Mackay, J; McClure, B; McLachlan, SA; Ngan, SY; Solomon, MJ, 2017)
"The standard treatment of stage II-III rectal cancer is preoperative chemoradiotherapy (CRT), followed by total mesorectal excision (TME)."2.82Oxaliplatin-based adjuvant chemotherapy rather than fluorouracil-based chemotherapy in rectal cancer is more efficient to decrease distant metastasis and increase survival after preoperative chemoradiotherapy and surgery: a meta-analysis. ( Kim, SH; Lee, JH; Song, JH; Um, JW, 2022)
"DPD deficiency was suspected because he developed many severe adverse events of capecitabine early and was finally confirmed based on the finding of a low DPD activity level in peripheral blood mononuclear cells."2.82Severe Gastrointestinal Disorder Due to Capecitabine Associated with Dihydropyrimidine Dehydrogenase Deficiency: A Case Report and Literature Review. ( Akutsu, D; Fukuda, S; Hagiwara, Y; Ikeda, N; Inagaki, Y; Kobayashi, M; Moriwaki, T; Narasaka, T; Niisato, Y; Onoda, T; Suzuki, H; Tange, Y; Tomisaki, R; Tsuchiya, K; Tsuji, M; Yamada, K; Yamada, T; Yamamoto, Y, 2022)
"Localized rectal cancer should be managed surgically."2.82Management of Rectal Cancer. ( Schlechter, BL, 2022)
"In the remaining seven (20%), the residual tumour clinically appeared benign."2.82Watch and wait policy after preoperative radiotherapy for rectal cancer; management of residual lesions that appear clinically benign. ( Bujko, K; Malinowska, M; Mroz, A; Pietrzak, L; Rupinski, M; Rutkowski, A; Szczepkowski, M; Wyrwicz, L, 2016)
"With the changed dosing schedule, this regimen was very well tolerated."2.82Phase I study of pre-operative continuous 5-FU and sorafenib with external radiation therapy in locally advanced rectal adenocarcinoma. ( Almhanna, K; Campos, T; Chen, DT; Hoffe, SE; Jiang, K; Kim, R; Prithviraj, GK; Shibata, D; Shridhar, R; Strosberg, J; Zhao, X, 2016)
"In this cohort of rectal cancer patients dominated by T4 and advanced T3 cases given sequential oxaliplatin-containing preoperative therapy with acceptable toxicity, high tumour response rates and overall survival were obtained, consistent with both local and systemic effects."2.82Oxaliplatin-containing Preoperative Therapy in Locally Advanced Rectal Cancer: Local Response, Toxicity and Long-term Outcome. ( Boye, K; Dueland, S; Flatmark, K; Folkvord, S; Giercksky, KE; Grøholt, KK; Hole, KH; Larsen, SG; Ree, AH; Saelen, MG; Seierstad, T; Wiig, JN, 2016)
"Patients with cT2-4 N0-2 M0 rectal cancer treated by standard CRT (54Gy and 2 cycles of 5FU-based chemotherapy) or extended CRT (54Gy and 6 cycles of 5FU-based chemotherapy) underwent sequential PET/CT imaging at baseline, 6 weeks and 12 weeks from radiation completion."2.82Consolidation chemotherapy during neoadjuvant chemoradiation (CRT) for distal rectal cancer leads to sustained decrease in tumor metabolism when compared to standard CRT regimen. ( Buchpiguel, CA; Fernandez, LM; Figueiredo, MN; Gama-Rodrigues, J; Habr-Gama, A; Perez, RO; Proscurshim, I; São Julião, GP, 2016)
"Consecutive patients with distal rectal cancer undergoing neoadjuvant chemoradiation (50."2.82Impact of Organ-Preserving Strategies on Anorectal Function in Patients with Distal Rectal Cancer Following Neoadjuvant Chemoradiation. ( Fernandez, LM; Gama-Rodrigues, J; Habr-Gama, A; Jorge, JM; Lynn, PB; Perez, RO; Proscurshim, I; São Julião, GP, 2016)
"The rates of anastomotic leakage and stenosis were calculated for each treatment arm."2.82Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial. ( Deng, Y; Ma, T; Qin, Q; Wang, H; Wang, J; Wang, L; Zheng, J; Zhou, Z, 2016)
"Kaplan-Meier plots from colon cancer patients showed a significant treatment benefit in patients with low maspin expression, but not for individuals with medium/high expression."2.80Nuclear maspin expression as a predictive marker for fluorouracil treatment response in colon cancer. ( Brydøy, M; Dahl, O; Hestetun, KE; Myklebust, MP, 2015)
"Dutch Colorectal Cancer group, CKTO 2003-16, ISRCTN36266738."2.80Adjuvant chemotherapy for rectal cancer patients treated with preoperative (chemo)radiotherapy and total mesorectal excision: a Dutch Colorectal Cancer Group (DCCG) randomized phase III trial. ( Berglund, Å; Breugom, AJ; Fokstuen, T; Gelderblom, H; Glimelius, B; Kapiteijn, E; Leer, JWH; Marijnen, CAM; Martijn, H; Meershoek-Klein Kranenbarg, E; Muller, EW; Nagtegaal, ID; Påhlman, L; Punt, CJA; Putter, H; Roodvoets, AGH; Rutten, HJT; Steup, WH; van de Velde, CJH; van den Broek, CBM; van Gijn, W, 2015)
" The target was to achieve pathological complete response (pCR; residual disease-free stage) and toxicities of grade ≤2, using individual dosing predicted according to the steady-state plasma concentration (C ss) and pharmacokinetic parameters of 5-FU: the area under the time-concentration curve at steady state (AUC) and clearance (CL)."2.80Kinetically guided neoadjuvant chemoradiotherapy based on 5-Fluorouracil in patients with locally advanced rectal cancer. ( Chládek, J; Grim, J; Hroch, M; Jaroslav, C; Jiří, P; Jiřina, M; Martínková, J; Miloš, H; Petera, J, 2015)
"Capecitabine (825 mg/m(2)) was delivered orally twice daily for the duration of radiotherapy."2.80Prospective phase II trial of nimotuzumab in combination with radiotherapy and concurrent capecitabine in locally advanced rectal cancer. ( Fan, YT; Feng, HY; Jin, T; Ju, HX; Li, DC; Liu, LY; Liu, Y; Luo, JL; Zhou, N; Zhu, Y; Zhu, YP, 2015)
"All clinical stage II and III rectal cancer patients received 50."2.80GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer. ( Cho, HM; Jung, JH; Kim, HJ; Kim, SH; Lee, HY; Lee, JH; Lee, KM; Shim, BY, 2015)
"5-fluorouracil (5-FU) bolus was administrated during first and last 3 days of radiotherapy."2.80Induction FOLFOX followed by preoperative hyperfractionated radiotherapy plus bolus 5-fluorouracil in locally advanced rectal carcinoma: single arm phase I-II study. ( Aboelnaga, EM; Daoud, MA; Eladl, EI; Zaid, AM, 2015)
"Patients with locally advanced rectal cancer received sandwich-like neoadjuvant therapy with bevacizumab (induction therapy with bevacizumab and FOLFOX, concurrent chemoradiotherapy with bevacizumab and consolidation chemotherapy with FOLFOX)."2.80Sandwich-like neoadjuvant therapy with bevacizumab for locally advanced rectal cancer: a phase II trial. ( Chen, Z; Deng, Y; Huang, Y; Lan, P; Li, W; Peng, J; Ren, D; Wang, J; Wang, L; Xiao, J; Yang, Z; Zheng, J, 2015)
"Neoadjuvant radiotherapy of rectal cancer represents the current standard of care."2.80Chemotherapy Alone for Patients With Stage II/III Rectal Cancer Undergoing Radical Surgery. ( Ahmed, BM; AlGizawy, SM; Essa, HH, 2015)
"Patients with locally advanced rectal cancer who achieve a pathological complete response to neoadjuvant chemoradiation have an improved prognosis."2.80Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial. ( Avila, K; Cataldo, PA; Chow, OS; Coutsoftides, T; Dietz, DW; Fichera, A; Garcia-Aguilar, J; Herzig, DO; Hunt, SR; Kumar, AS; Marcet, JE; Oommen, S; Patil, S; Polite, BN; Smith, DD; Stamos, MJ; Ternent, CA; Varma, MG, 2015)
"1804 rectal cancer patients, staged cT3-4N0-2M0, participated in a multicenter study."2.80Carcinoembryonic antigen has prognostic value for tumor downstaging and recurrence in rectal cancer after preoperative chemoradiotherapy and curative surgery: A multi-institutional and case-matched control study of KROG 14-12. ( Baek, JY; Chie, EK; Cho, HM; Jang, HS; Jeong, BK; Jeong, JU; Kim, DY; Kim, JH; Kim, JS; Kim, K; Kim, SH; Kim, SY; Kim, TH; Lee, JH; Nam, TK; Oh, JH; Shim, BY; Yoon, MS, 2015)
" Preclinical evidence suggests that the scheduling of bevacizumab may be crucial to optimize its combination with chemo-radiotherapy."2.80Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: Results of the BRANCH trial. ( Aloj, L; Avallone, A; Bianco, F; Botti, G; Budillon, A; Caracò, C; Comella, P; Delrio, P; Granata, V; Iaffaioli, VR; Leone, A; Marone, P; Muto, P; Pecori, B; Petrillo, A; Romano, C; Romano, G; Tatangelo, F, 2015)
"Patients with clinical stage II or III rectal cancer undergoing preoperative radiation were randomly assigned to one of four chemotherapy regimens in a 2x2 design: CVI 5-FU or oral capecitabine with or without oxaliplatin."2.80Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial. ( Allegra, CJ; Arora, A; Bahary, N; Beart, RW; Eakle, JF; Evans, LS; Landry, JC; Marchello, BT; Moore, DF; Mullane, MR; O'Connell, MJ; Pitot, HC; Robertson, JM; Roh, MS; Ryan, DP; Sharif, S; Shields, AF; Soori, G; Ward, PJ; Wolmark, N; Wozniak, TF; Yothers, G, 2015)
"However, relevant stoma morbidity after rectal cancer surgery exists and has a significant impact on quality of life."2.80CoCStom trial: study protocol for a randomised trial comparing completeness of adjuvant chemotherapy after early versus late diverting stoma closure in low anterior resection for rectal cancer. ( Herrle, F; Hinke, A; Hofheinz, RD; Kienle, P; Post, S; Rossion, I; Sandra-Petrescu, F; Suelberg, H, 2015)
"Stage II and III rectal cancer patients received, after total mesorectal excision, 2 cycles of XELOX regimen (oxaliplatin 130 mg/m(2) on day 1; capecitabine 1000 mg/m(2) bid on day 1 to 14, q21), followed by capecitabine (800 mg/m(2) bid daily; 20% dose at 12:00 AM and 80% dose at 12:00 PM) administered continuously during pelvic radiation (total 50."2.79Chronomodulated capecitabine and adjuvant radiation in intermediate-risk to high-risk rectal cancer: a phase II study. ( Bajetta, E; Biondani, P; Buzzoni, R; Di Bartolomeo, M; Dotti, KF; Ferrario, E; Formisano, B; Gevorgyan, A; Grassi, P; Mariani, L; Pietrantonio, F; Valvo, F, 2014)
"To establish a safe regimen of high-dose regional chemotherapy with NIPP using cisplatin in patients with incurable rectal cancer."2.79Negative-balance isolated pelvic perfusion in patients with incurable symptomatic rectal cancer: results and drug dose correlation to adverse events. ( Kim, C; Kimata, R; Kumita, S; Murata, S; Onozawa, S; Tajima, H; Uchida, E, 2014)
"Data from 62 patients with rectal cancer (uT3-4; N0/1, M0) of the phase II trial were analyzed."2.79Analysis of bevacizumab-based preoperative radiochemotherapy in patients with locally advanced rectal cancer on surgery-associated spectrum of complications. ( Arnold, D; Buller, J; Dellas, K; Dunst, J; Görtz, GJ; Höhler, T; Keck, T; Richter, M; Zühlke, H, 2014)
"Capecitabine dose was increased from 650 mg/m(2) to 825 mg/m(2) orally twice daily on the days of radiation therapy; erlotinib dose was increased from 50 mg orally daily in weeks 1 to 3, to 50 mg daily in weeks 1 to 6, to 100 mg daily in weeks 1 to 6."2.79Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal cancer: a phase 1 trial. ( Chang, GJ; Clemons, MV; Crane, CH; Das, P; Delclos, ME; Eng, C; Garrett, CR; Kopetz, SE; Krishnan, S; Maru, DM; Munsell, MF; Rodriguez-Bigas, MA; Shureiqi, I; Skibber, JM; You, YN, 2014)
"Eighty patients with rectal cancer located in the mid to low rectum, staged cT3-4N0-2M0, were prospectively enrolled."2.79Two-week course of preoperative chemoradiotherapy followed by delayed surgery for rectal cancer: a phase II multi-institutional clinical trial (KROG 11-02). ( Baek, JY; Chie, EK; Choi, DH; Chun, HG; Jang, HS; Kim, DY; Kim, HC; Kim, JG; Kim, SY; Kim, TH; Lee, JH; Lee, MA; Oh, JH; Oh, ST; Park, HC; Park, JW; Park, YS, 2014)
"Patients with cT3-4, any N, any M rectal cancer were eligible."2.79Five fractions of radiation therapy followed by 4 cycles of FOLFOX chemotherapy as preoperative treatment for rectal cancer. ( Birnbaum, E; Fleshman, J; Gao, F; Hall, L; Hunt, S; Kodner, I; Lockhart, AC; Mutch, M; Myerson, RJ; Naughton, M; Olsen, J; Parikh, P; Picus, J; Rigden, C; Safar, B; Sorscher, S; Suresh, R; Tan, B; Wang-Gillam, A, 2014)
"Patients with clinical stage II or III rectal cancer who were undergoing preoperative RT (45 Gy in 25 fractions over 5 weeks plus a boost of 5."2.79Capecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04. ( Allegra, CJ; Arora, A; Bahary, N; Beart, RW; Colangelo, LH; Eakle, J; Evans, LS; Landry, JC; Marchello, BT; Mohiuddin, M; Moore, DF; Mullane, MR; O'Connell, MJ; Parda, DS; Petrelli, NJ; Pitot, HC; Robertson, JM; Roh, MS; Ryan, DP; Sharif, S; Shields, AF; Soori, GS; Ward, PJ; Wolmark, N; Wozniak, TF; Yothers, G, 2014)
"Brunch Regimen for locally advanced rectal cancer consisting of neoadjuvant chronomodulated capecitabine and concurrent radiation therapy is effective and well tolerated with good safety profile, particularly with regard to the occurrence of hand and foot syndrome, in patients with locally advanced rectal cancer."2.79Neoadjuvant chronomodulated capecitabine with radiotherapy in rectal cancer: a phase II brunch regimen study. ( Akgun, Z; Balik, E; Cipe, G; Gural, Z; Kaytan-Saglam, E; Kilickap, S; Okyar, A; Saglam, S; Yildiz, S; Yucel, S, 2014)
"In T3 rectal cancer (RC), preoperative chemoradiotherapy [5-fluorouracil (5-FU-RT)] reduces local recurrences, but does not affect overall survival."2.79Pathological response and safety of two neoadjuvant strategies with bevacizumab in MRI-defined locally advanced T3 resectable rectal cancer: a randomized, noncomparative phase II study. ( Adenis, A; André, T; Azria, D; Borg, C; Bosset, JF; Boudghène, F; Maingon, P; Mantion, G; Mornex, F; Morsli, O; Piutti, M, 2014)
"Capecitabine was administered on weekdays concurrently with pelvic radiotherapy at a daily dose of 1."2.79Neoadjuvant capecitabine, bevacizumab and radiotherapy for locally advanced rectal cancer: results of a single-institute Phase I study. ( Hirakawa, K; Hosono, M; Maeda, K; Miki, Y; Nagahara, H; Shimatani, Y; Tsutsumi, S, 2014)
"Patients (pts) with metastatic rectal cancer and symptomatic primary, require local and systemic control."2.79Phase II trial evaluating the feasibility of interdigitating folfox with chemoradiotherapy in locally advanced and metastatic rectal cancer. ( Bressel, M; Chander, S; Cooray, P; Heriot, A; Hicks, R; Jefford, M; Leong, T; MacKay, JR; McClure, B; McKendrick, J; Michael, M; Ngan, SY; Steel, M; Zalcberg, J, 2014)
"However, the role of MRI in restaging rectal tumors after neoadjuvant CRT is contentious."2.79Prediction of pathologic staging with magnetic resonance imaging after preoperative chemoradiotherapy in rectal cancer: pooled analysis of KROG 10-01 and 11-02. ( Baek, JY; Chie, EK; Jang, HS; Jung, JH; Kim, DY; Kim, HC; Kim, JG; Kim, SY; Kim, TH; Lee, JH; Lee, MA; Nam, TK; Oh, JH; Oh, ST; Park, HC; Park, SC, 2014)
"Their role in chemoradiotherapy for rectal cancers is unclear."2.79Effect of neoadjuvant chemoradiation on tumor-infiltrating/associated lymphocytes in locally advanced rectal cancers. ( Bokey, L; Cheng, C; Chua, W; de Souza, P; Descallar, J; Lee, CS; Lee, MT; Lim, SH; Ng, W; Shin, JS; Solomon, M; Wong, K, 2014)
"Valproic acid (VPA) is an anti-epileptic drug with HDACi and anticancer activity."2.79Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid--short Radiotherapy--rectum 3rd trial). ( Aloj, L; Avallone, A; Bianco, F; Botti, G; Budillon, A; Caracò, C; Cavalcanti, E; D'Angelo, V; Daniele, G; Delrio, P; Di Gennaro, E; Di Maio, M; Gallo, C; Granata, C; Iaffaioli, VR; Lastoria, S; Maiolino, P; Marone, P; Maurea, N; Montano, M; Muto, P; Pecori, B; Perrone, F; Petrillo, A; Piccirillo, MC; Roca, MS; Romano, G; Silvestro, L; Tatangelo, F; Terranova Barberio, M, 2014)
"Patients with cT3 or cN1 and cM0 rectal cancer were eligible."2.79A prospective pilot study of target-guided personalized chemotherapy with intensity-modulated radiotherapy in patients with early rectal cancer. ( Cubillo, A; De Vicente, E; García-García, E; Hernando-Requejo, O; Hidalgo, M; López, U; López-Ríos, F; Morelli, P; Muro, A; Prados, S; Quijano, Y; Rodriguez-Pascual, J; Rubio, C, 2014)
"Adults with primary metastasized rectal cancer were enrolled."2.78Evaluation of short-course radiotherapy followed by neoadjuvant bevacizumab, capecitabine, and oxaliplatin and subsequent radical surgical treatment in primary stage IV rectal cancer. ( Beets, GL; Beukema, JC; de Jong, KP; Gelderblom, AJ; Havenga, K; Hospers, GA; Nagtegaal, ID; Rutten, HJ; Tamas, K; van de Velde, CJ; van Dijk, TH; Wiggers, T, 2013)
"A total of 32 patients had lower rectal cancer, with 24 candidate for abdominal-perineal resection."2.78Prospective phase II trial of neoadjuvant chemo-radiotherapy with Oxaliplatin and Capecitabine in locally advanced rectal cancer (XELOXART). ( Aglietta, M; Bertetto, O; Cassoni, P; Ciuffreda, L; Dongiovanni, V; Fanchini, L; Filippi, AR; Franco, P; Gabriele, P; Morino, M; Munoz, F; Racca, P; Ricardi, U; Rondi, N, 2013)
"Metronidazole 10 g/m(2) was administered per rectum on days 8 and 15."2.78Phase II study of concomitant chemoradiotherapy with local hyperthermia and metronidazole for locally advanced fixed rectal cancer. ( Barsukov, YA; Fedyanin, MY; Gordeyev, SS; Perevoshikov, AG; Tkachev, SI, 2013)
"The purpose of this study was to investigate the association between single nucleotide polymorphism (SNP) of CCND1 A870G and acute adverse events (AEs) in postoperative rectal cancer patients who received capecitabine-based postoperative chemoradiotherapy (CRT)."2.78[Impact of CCND1 A870G polymorphism on acute adverse events in postoperative rectal cancer patients treated with adjuvant concurrent chemoradiotherapy]. ( DU, ZL; Huang, Y; Jin, J; Li, YX; Lin, DX; Qiao, Y; Ren, H; Tan, W; Yu, DK, 2013)
"In selected patients with rectal cancer, laparoscopic surgery is as safe as open surgery, with similar resection margins and completeness of resection."2.78Postchemoradiation laparoscopic resection and intraoperative electron-beam radiation boost in locally advanced rectal cancer: long-term outcomes. ( Calvo, FA; del Valle, E; Diaz-Zorita, B; García-Sabrido, JL; Lopez-Baena, JA; Marcos, F; Muñoz-Calero, A; Rodriguez, M; Serrano, J; Sole, CV; Zorrilla, J, 2013)
"In stage IV rectal cancer, palliative surgery is often carried out upfront."2.78Palliative radiotherapy and chemotherapy instead of surgery in symptomatic rectal cancer with synchronous unresectable metastases: a phase II study. ( Bujko, K; Kepka, L; Michalski, W; Olszyna-Serementa, M; Palucki, J; Pietrzak, L; Rutkowski, A; Tyc-Szczepaniak, D; Wyrwicz, L, 2013)
"The role of HER2 in rectal cancer is unclear, as conflicting data on the prevalence of HER2 expression in this disease have been reported."2.78HER2 in high-risk rectal cancer patients treated in EXPERT-C, a randomized phase II trial of neoadjuvant capecitabine and oxaliplatin (CAPOX) and chemoradiotherapy (CRT) with or without cetuximab. ( Cervantes, A; Chau, I; Cunningham, D; Eltahir, Z; Glimelius, B; Gonzalez de Castro, D; Oates, J; Peckitt, C; Roy, A; Sclafani, F; Tabernero, J; Wotherspoon, A, 2013)
"The overall toxicity of oxaliplatin and continuous 5-FU/leucovorin infusion in combination with radiation was well tolerated."2.78Neoadjuvant treatment of mid-to-lower rectal cancer with oxaliplatin plus 5-fluorouracil and leucovorin in combination with radiotherapy: a Korean single center phase II study. ( Baek, JH; Jung, DH; Kwon, KA; Lee, KC; Lee, SH; Lee, WS; Shin, DB; Sym, SJ, 2013)
"Seventy-three patients with cT3-4 rectal cancer were enrolled."2.78Preoperative short-course concurrent chemoradiation therapy followed by delayed surgery for locally advanced rectal cancer: a phase 2 multicenter study (KROG 10-01). ( Baek, JY; Chang, HJ; Jang, HS; Kim, DY; Kim, JG; Kim, MJ; Kim, SY; Kim, TH; Lee, JH; Lee, MA; Nam, TK; Oh, JH; Park, JW; Yeo, SG, 2013)
"T3-4 and/or N+ rectal cancer patients were treated prospectively with capecitabine-based chemoradiation and total mesorectal excision 7-8 weeks later."2.78Is the standardized uptake value of FDG-PET/CT predictive of pathological complete response in locally advanced rectal cancer treated with capecitabine-based neoadjuvant chemoradiation? ( Alessi, A; Avuzzi, B; Bampo, C; Bertarelli, G; Biondani, P; Bombardieri, E; Chiruzzi, C; Crippa, F; de Braud, F; Di Bartolomeo, M; Fantini, S; Mariani, L; Milione, M; Pietrantonio, F; Valvo, F, 2013)
"Patients with locally advanced or low rectal cancer were treated with capecitabine 825 mg/m(2) twice daily on days 1-14 and 22-35, oxaliplatin 50mg/m(2) on days 1, 8, 22 and 29, bevacizumab 5mg/kg on days 14, 1, 15 and 29, and radiation 50."2.77Pre-operative bevacizumab, capecitabine, oxaliplatin and radiation among patients with locally advanced or low rectal cancer: a phase II trial. ( Berry, S; Easaw, J; Hay, J; Kennecke, H; Post, J; Rao, S; Tankel, K; Wong, R; Zhou, C, 2012)
"Patients with cT3 rectal cancer were eligible."2.77Preoperative treatment with capecitabine, bevacizumab and radiotherapy for primary locally advanced rectal cancer--a two stage phase II clinical trial. ( De Vries, A; Eisterer, W; Gnant, M; Jagoditsch, M; Öfner, D; Rabl, H; Resch, G; Thaler, J, 2012)
"Clinically staged T2N0 rectal cancer patients were treated with capecitabine and oxaliplatin during radiation followed by LE."2.77A phase II trial of neoadjuvant chemoradiation and local excision for T2N0 rectal cancer: preliminary results of the ACOSOG Z6041 trial. ( Cataldo, P; Chan, E; Garcia-Aguilar, J; Marcet, J; Medich, D; Oommen, S; Pigazzi, A; Posner, MC; Shi, Q; Thomas, CR, 2012)
"Patients with Stage T3 or T4 rectal cancer of <12 cm from the anal verge were randomized to preoperative RT (50."2.77Radiation Therapy Oncology Group 0247: a randomized Phase II study of neoadjuvant capecitabine and irinotecan or capecitabine and oxaliplatin with concurrent radiotherapy for patients with locally advanced rectal cancer. ( Anne, PR; Erickson, BA; Haddock, M; Kachnic, L; Lee, RJ; Meropol, NJ; Mitchell, E; Pollock, J; Rashid, A; Watson, JC; Willett, CG; Winter, K; Wong, SJ, 2012)
"Transforming growth factor-beta1 is related to adverse events in radiochemotherapy."2.77Acute toxicity of radiochemotherapy in rectal cancer patients: a risk particularly for carriers of the TGFB1 Pro25 variant. ( Becker, H; Beissbarth, T; Brockmöller, J; Christiansen, H; Conradi, LC; Gaedcke, J; Ghadimi, M; Hennies, S; Herrmann, MK; Hess, CF; Jo, P; Mergler, CP; Rave-Fränk, M; Schirmer, MA; Wolff, HA, 2012)
"Patients with T3 to T4 and/or N+ rectal cancer received preoperative IMRT (47."2.77Four-week neoadjuvant intensity-modulated radiation therapy with concurrent capecitabine and oxaliplatin in locally advanced rectal cancer patients: a validation phase II trial. ( Arbea, L; Aristu, J; Cambeiro, M; Chopitea, A; Díaz-González, JA; García-Foncillas, J; Gaztañaga, M; Hernández, JL; Martínez-Monge, R; Moreno, M; Nuñez, J; Ramos, LI; Rodríguez, J; Sola, JJ; Subtil, JC, 2012)
"Capecitabine was administered at 825 t."2.77Phase II trial of concomitant neoadjuvant chemotherapy with oxaliplatin and capecitabine and intensity-modulated radiotherapy (IMRT) in rectal cancer. ( Alberola Candel, V; Alberola, A; Garde Noguera, J; Gasent Blesa, JM; Giner Bosch, V; Laforga Canales, JB; Peris Godoy, M; Provencio Pulla, M; Sanchez, JL; Soler Tortosa, M, 2012)
"Locally advanced rectal cancer represents a major therapeutic challenge."2.77Dose-effect relationship in chemoradiotherapy for locally advanced rectal cancer: a randomized trial comparing two radiation doses. ( Appelt, A; Jakobsen, A; Lindebjerg, J; Ploen, J; Rafaelsen, SR; Vuong, T, 2012)
"Patients with T3/T4 or node positive rectal cancer were treated with capecitabine 1,000 mg/m(2) twice daily (BID) days 1-14, and irinotecan 200 mg/m(2) on day 1 every 21 days for 2 cycles, followed by capecitabine 825 mg/m(2) BID days 1-5 per week with concurrent radiotherapy 50."2.77Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal cancer: Hoosier Oncology Group GI03-53. ( Bufill, J; Burns, M; Cardenes, H; Chiorean, EG; Clark, R; Coleman, N; Curie, C; Hinkle, DT; LeBlanc, J; Loehrer, PJ; Robb, B; Sanghani, S; Schiel, MA; Tong, Y; Yu, M, 2012)
"Capecitabine was administered at 825 mg/m(2) twice daily for 5 days/week and oxaliplatin at 50 mg/m(2) on day 1 weekly for 5 weeks starting the first day of RT (before RT)."2.77Phase II study of preoperative radiotherapy and concomitant weekly intravenous oxaliplatin combined with oral capecitabine for stages II-III rectal cancer. ( Alonso, V; Aranda, E; Benavides, M; Escudero, P; Gallén, M; Gómez, A; González, E; Losa, F; Majem, M; Massutí, B; Navarro, M; Rivera, F; Salazar, R, 2012)
"Patients with clinical T3, T4, or N1-2 rectal cancer were subjected to a preoperative CCRT protocol with FOLFOX and bevacizumab (5 mg/kg) biweekly for 6 cycles followed by a standardized laparoscopic TME procedure, as detailed in the attached video."2.76Technical feasibility of laparoscopic total mesorectal excision for patients with low rectal cancer after concurrent radiation and chemotherapy with bevacizumab plus FOLFOX. ( Cheng, KW; Lai, HS; Liang, JT, 2011)
"Patients (N = 207) with nonresectable rectal cancer were randomized to preoperative CRT or RT (2 Gy × 25 ± 5-fluorouracil/leucovorin)."2.76Late patient-reported toxicity after preoperative radiotherapy or chemoradiotherapy in nonresectable rectal cancer: results from a randomized Phase III study. ( Berglund, Å; Bruheim, K; Brændengen, M; Cvancarova, M; Glimelius, B; Tveit, KM, 2011)
"In patients with locally advanced rectal cancer (LARC), preoperative chemoradiation is known to improve local control, and down-staging of the tumor serves as a surrogate for survival."2.76Preoperative oxaliplatin, capecitabine, and external beam radiotherapy in patients with newly diagnosed, primary operable, cT₃NxM0, low rectal cancer: a phase II study. ( Devries, AF; Eisterer, W; Fastner, G; Gnant, M; Greil, R; Jäger, R; Kapp, KS; Keil, F; Offner, F; Ofner, D; Rabl, H; Schaberl-Moser, R; Thaler, J; Tschmelitsch, J; Zitt, M, 2011)
"Patients with locally advanced rectal cancer (cT3, potentially resectable cT4 or N+) were randomly assigned to receive preoperative or postoperative CRT."2.76Randomized phase 3 trial comparing preoperative and postoperative chemoradiotherapy with capecitabine for locally advanced rectal cancer. ( Kim, JC; Kim, JH; Kim, TW; Park, JH; Yoon, SM; Yu, CS, 2011)
"Grade 3-4 toxicity during neoadjuvant treatment was diarrhea (38."2.76Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (StarPan/STAR-02 Study). ( Aprile, G; Aschele, C; Bardelli, A; Bochicchio, A; Di Fabio, F; Garufi, C; Giaquinta, S; Gion, M; Latiano, T; Maiello, E; Martoni, A; Pini, S; Pinto, C; Rosati, G; Torri, V, 2011)
"Results of this small pilot study in rectal cancer patients receiving preoperative radiochemotherapy, showed that ingestion of larger quantities of glutamine given more often as previously reported did not diminish the incidence and severity of diarrhoea and did not affect inflammatory and metabolic activity compared to the placebo treatment with maltodextrin."2.76Oral glutamine supplementation during preoperative radiochemotherapy in patients with rectal cancer: a randomised double blinded, placebo controlled pilot study. ( Anderluh, F; Kompan, L; Mlakar Mastnak, D; Možina, B; Oblak, I; Rotovnik Kozjek, N; Soeters, P; Velenik, V; Zadnik, V, 2011)
"Among the 17 patients with lower rectal cancer, thirteen (76%) were originally indicated for abdominal-perineal resection (APR)."2.76A phase II study of neoadjuvant chemoradiotherapy with oxaliplatin and capecitabine for rectal cancer. ( Bai, C; Chen, S; Guan, M; Jia, N; Qiu, H; Shao, Y; Xiao, Y; Yang, T; Zhang, F; Zhao, L; Zhong, G, 2011)
"This phase II study is performed to evaluate the efficacy and safety of capecitabine combined with preoperative radiotherapy (RT) in Chinese patients with locally advanced rectal cancer (LARC)."2.76Preoperative radiotherapy combined with capecitabine chemotherapy in Chinese patients with locally advanced rectal cancer. ( Deng, J; Jin, J; Li, X; Lu, W; Meng, H; Wang, F; Xu, X; Xue, Z; Zhang, H; Zhou, G, 2011)
" Relationships between genetic variants and adverse events, tumour response, overall and disease-free survivals were assessed."2.76Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer. ( Alyasiri, A; Dvorak, A; Fleshman, JW; Hoskins, JM; McLeod, HL; Motsinger-Reif, AA; Myerson, RJ; Roy, S; Tan, BR; Thomas, F, 2011)
"Neoadjuvant chemoradiotherapy for rectal cancer can result in complete disappearance of tumor and involved nodes."2.76Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer. ( Beets, GL; Beets-Tan, RG; Buijsen, J; Engelen, SM; Hulsewé, KW; Jansen, RL; Lambregts, DM; Lammering, G; Leijtens, JW; Maas, M; Nelemans, PJ; Sosef, M; van Dam, RM, 2011)
"A total of 41 patients of low rectal cancer were treated with CPT-11, 5-FU therapy or CPT-11 plus 5-FU combined short-term radiotherapy from April 2002 to April 2009."2.76[Pathological changes of rectal cancer after irinotecan, 5-fluorouracil or combined short-term radiotherapy]. ( Chen, MX; Fan, L; Hu, XZ; Jiang, HY; Li, CY; Liang, XB; Ma, JJ; Yan, D, 2011)
"Celecoxib dosage was fixed."2.75A phase I study of capecitabine, irinotecan, celecoxib, and radiation as neoadjuvant therapy of patients with locally advanced rectal cancer. ( Alqaisi, M; Bernal, P; Bush, D; Byrd, J; Garberoglio, C; Hussein, F; Malik, I, 2010)
"Preoperative treatment of rectal cancer with combined chemotherapy and radiation therapy has become a widely accepted strategy."2.75A phase II trial of neoadjuvant capecitabine combined with hyperfractionated accelerated radiation therapy in locally advanced rectal cancer. ( Chang, M; George, TJ; Grobmyer, S; Hochwald, S; King, J; Larson, B; Marsh, Rde W; Mendenhall, WM; Siddiqui, T; Zlotecki, RA, 2010)
"Patients with poor-risk rectal cancer defined by MRI can be at high risk of disease recurrence despite standard chemoradiotherapy and optimum surgery."2.75Neoadjuvant capecitabine and oxaliplatin before chemoradiotherapy and total mesorectal excision in MRI-defined poor-risk rectal cancer: a phase 2 trial. ( Barbachano, Y; Brown, G; Chau, I; Chua, YJ; Cunningham, D; Massey, A; Oates, JR; Tait, D; Tebbutt, NC; Wotherspoon, A, 2010)
"Cap 50 merits investigation for T3-4 rectal cancers."2.75Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2. ( Azria, D; Bécouarn, Y; Berdah, JF; Bouché, O; Conroy, T; de La Roche, G; Denis, B; Dupuis, O; Etienne, PL; François, E; Gérard, JP; Gourgou-Bourgade, S; Hennequin, C; Lledo, G; Mahé, MA; Martel-Laffay, I; Mineur, L; Mirabel, X; Montoto-Grillot, C; Vendrely, V, 2010)
"Radiation injuries were reported in 37."2.75[Extended preoperative course of radiotherapy as component of combined and complex treatment of locally-advanced ampular rectal cancer]. ( Lukina, EIu; Nadvikova, EA; Semikopov, KV; Vazhenin, AV, 2010)
"Bortezomib was administered on days 1, 4, 8, and 11 every 21 days for 2 cycles with 5-fluorouracil at 225 mg/m2/day continuously and 50."2.75A phase I study of bortezomib in combination with standard 5-fluorouracil and external-beam radiation therapy for the treatment of locally advanced or metastatic rectal cancer. ( Bernard, SA; Calvo, BF; Caskey, LS; Chakravarthy, AB; Chan, E; Goldberg, RM; Ivanova, A; Kim, HJ; Myers, MO; O'Neil, BH; Raftery, L; Sanoff, HK; Tepper, JE; Wise, PE, 2010)
" Of all biomarkers, pretreatment plasma sVEGFR-1-an endogenous blocker of VEGF and PlGF, and a factor linked with "vascular normalization"-was associated with both primary tumor regression and the development of adverse events after neoadjuvant bevacizumab and chemoradiation."2.75Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer. ( Ancukiewicz, M; Bentley, R; Carroll, M; Clark, JW; Czito, BG; di Tomaso, E; Duda, DG; Jain, RK; Lauwers, GY; Mantyh, C; Poleski, M; Shah, M; Shellito, P; Tyler, D; Willett, CG, 2010)
"The detection of somatic mutations in rectal cancer tumors led us to re-evaluate the utility of the tests performed in blood samples for these polymorphisms in rectal cancer."2.75Pharmacogenetic analysis in neoadjuvant chemoradiation for rectal cancer: high incidence of somatic mutations and their relation with response. ( Balboa, E; Barros, F; Carracedo, A; Celeiro-Muñoz, C; Duran, G; Gomez-Caamaño, A; Lamas, MJ; Lopez, R, 2010)
"Standard adjuvant chemoradiotherapy of rectal cancer still consists of 5-fluorouracil (5-FU) only."2.75Adjuvant chemoradiotherapy of advanced resectable rectal cancer: results of a randomised trial comparing modulation of 5-fluorouracil with folinic acid or with interferon-α. ( Baumann, W; Henne-Bruns, D; Kornmann, M; Kreuser, ED; Kron, M; Link, KH; Staib, L; Wiegel, T, 2010)
"Patients with T3, T4, or N+ rectal cancer received radiotherapy to a total dose of 50."2.75A pilot feasibility study of TNFerade™ biologic with capecitabine and radiation therapy followed by surgical resection for the treatment of rectal cancer. ( Alexander, HR; Camphausen, K; Citrin, D; Denobile, J; Libutti, SK; Pingpank, JF; Quezado, M; Royal, RE; Seidel, G; Shuttack, Y; Steinberg, SM; Wood, BJ, 2010)
" The purpose of this study was to evaluate whether preoperative chemoradiation therapy exerted an adverse influence on laparoscopic TME for low rectal cancer."2.74Safety of laparoscopic total mesorectal excision for low rectal cancer with preoperative chemoradiation therapy. ( Akiyoshi, T; Fujimoto, Y; Fukuda, M; Konishi, T; Kuroyanagi, H; Muto, T; Oya, M; Ueno, M; Yamaguchi, T, 2009)
"Oral capecitabine was well tolerated in all patients; grade 3 toxicity was seen in only one patient (3."2.74Preoperative concomitant radiotherapy with oral capecitabine in advanced rectal cancer within 6 cm from anal verge. ( Elshazly, WG; Farouk, M; Samy, M, 2009)
"To evaluate the safety and efficacy of preoperative radiotherapy (RT) in combination with cetuximab, capecitabine, and irinotecan in patients with locally advanced rectal cancer."2.74Cetuximab in combination with capecitabine, irinotecan, and radiotherapy for patients with locally advanced rectal cancer: results of a Phase II MARGIT trial. ( Barreto-Miranda, M; Dinter, D; Erben, P; Hochhaus, A; Hofheinz, RD; Horisberger, K; Kähler, G; Kienle, P; Mai, S; Post, S; Ströbel, P; Treschl, A; Wenz, F; Willeke, F; Woernle, C, 2009)
"However, the German Rectal Cancer Study Group recently demonstrated that preoperative radiochemotherapy (RCT) was better than postoperative radiochemotherapy in terms of local control."2.74Preoperative short-course radiotherapy versus combined radiochemotherapy in locally advanced rectal cancer: a multi-centre prospectively randomised study of the Berlin Cancer Society. ( Budach, V; Burock, S; Dietel, M; Koswig, S; Kretzschmar, A; Loy, V; Schlag, PM; Siegel, R; Wernecke, KD, 2009)
"Fifty-four patients with T3/T4/N+ rectal cancers were treated on a Phase II trial using preoperative capecitabine and concomitant boost radiotherapy."2.74Temporal patterns of fatigue predict pathologic response in patients treated with preoperative chemoradiation therapy for rectal cancer. ( Cleeland, CS; Crane, CH; Das, P; Delclos, ME; Hundal, M; Janjan, NA; Krishnan, S; Lin, EH; Mendoza, TR; Park, HC; Vadhan-Raj, S; Wang, XS; Zhang, Y, 2009)
"However, the subgroup of colon cancer with stage III exhibited a statistically significant difference both for DFS, 58% vs."2.74Final results of a randomised phase III study on adjuvant chemotherapy with 5 FU and levamisol in colon and rectum cancer stage II and III by the Norwegian Gastrointestinal Cancer Group. ( Bjerkeset, O; Carlsen, E; Dahl, O; Eide, TJ; Fluge, Ø; Halvorsen, TB; Myrvold, HE; Podhorny, N; Tveit, KM; Vonen, B; Wiig, JN, 2009)
"Forty-one patients with rectal cancer (T3-4 and/or N+) received preoperative radiotherapy (1."2.74Molecular response to cetuximab and efficacy of preoperative cetuximab-based chemoradiation in rectal cancer. ( Aydin, S; Daemen, A; De Moor, B; Debucquoy, A; Gevaert, O; Haustermans, K; Libbrecht, L; Machiels, JP; McBride, WH; Penninckx, F; Scalliet, P; Sempoux, C; Stroh, C; Tejpar, S; Vlassak, S, 2009)
"Between 1993 and 2003, 186 rectal cancer patients were enrolled."2.74Longitudinal assessment of quality of life in rectal cancer patients with or without stomas following primary resection. ( Barbachano, Y; Chau, I; Chong, G; Cunningham, D; Watkins, D; Yau, T, 2009)
"Bevacizumab with chemoradiotherapy appears safe and active and yields promising survival results in locally advanced rectal cancer."2.74Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study. ( Ancukiewicz, M; Bentley, R; Boucher, Y; Chen, HX; Chung, DC; Clark, JW; Czito, BG; di Tomaso, E; Duda, DG; Fischman, AJ; Jain, RK; Lahdenranta, J; Lauwers, GY; Paulson, E; Poleski, M; Sahani, DV; Shellito, P; Vujaskovic, Z; Willett, CG; Wong, TZ, 2009)
"Treatment of rectal cancer requires a multidisciplinary approach with standardized surgical, pathological and radiotherapeutic procedures."2.74Surgical treatment for locally advanced lower third rectal cancer after neoadjuvent chemoradiation with capecitabine: prospective phase II trial. ( Elsayed, MI; Elwanis, MA; Maximous, DW; Mikhail, NN, 2009)
"Capecitabine was given at 725 mg/m(2) orally twice daily Monday through Friday concurrently with RT."2.73Phase II study of weekly intravenous oxaliplatin combined with oral daily capecitabine and radiotherapy with biologic correlates in neoadjuvant treatment of rectal adenocarcinoma. ( Andrews, C; Bullarddunn, K; Fakih, MG; Levea, C; Park, YM; Pendyala, L; Puthillath, A; Rajput, A; Ross, ME; Rustum, YM; Toth, K; Yang, GY, 2008)
"2004, 256 cases with stage III colorectal cancer randomized received de Gramont, modified FOLFOX4 (mFOLFOX4) and XELOX regimens."2.73[Clinical observation of XELOX (Capecitabine puls Oxaliplatin): an adjuvant chemotherapy regimen used in stage III colorectal cancer]. ( Cheng, RC; Diao, C; Liu, QY; Su, YJ; Wei, XP; Xu, JB; Zhang, JM, 2008)
"40 patients with rectal cancer UICC stage II/III, receiving pre-operative 5-FU-based CT/RT followed by standardized surgery, including total mesorectal excision, were investigated."2.73Thymidylate synthase genotypes and tumour regression in stage II/III rectal cancer patients after neoadjuvant fluorouracil-based chemoradiation. ( Aust, DE; Baretton, GB; Ehninger, G; Goekkurt, E; Jakob, C; Kramer, M; Liersch, T; Mogck, U; Stoehlmacher, J, 2008)
"Irinotecan 180 mg/m2 was administered biweekly on D1, LV 200 mg/m2 by intravenous infusion in 2 hours before bolus intravenous injection of 5-Fu 400 mg/m2, then followed immediately by intravenous infusion of 5-Fu 2."2.73[Irinotecan plus fuorouracil/leucovorin (FOLFIRI) as a second line chemotherapy for refractory or metastatic colorectal cancer]. ( Bai, Y; Chu, YP; Jin, ML; Li, J; Liu, DQ; Shen, L; Wang, YH; Xu, JM; Zhang, XD, 2008)
" The secondary aim was to evaluate whether distal bowel clearance < or =1 cm is safe after radiation."2.73Distal bowel surgical margin shorter than 1 cm after preoperative radiation for rectal cancer: is it safe? ( Bujko, K; Chmielik, E; Nasierowska-Guttmejer, A; Nowacki, MP; Rutkowski, A; Wojnar, A, 2008)
"Capecitabine was given at an oral dosage of 825 mg/m(2)bid on each day of the radiotherapy period with the first daily dose applied 2 h before irradiation, followed by surgery 6 weeks later."2.73Neoadjuvant capecitabine combined with standard radiotherapy in patients with locally advanced rectal cancer: mature results of a phase II trial. ( Budach, W; Debus, J; Dunst, J; Hinke, A; Hoelscher, T; Mose, S; Reese, T; Roedel, C; Rudat, V; Wulf, J; Zuehlke, H, 2008)
"Capecitabine was administered concurrently at 1,650 mg/m2 on days 1 to 14 and 22 to 35, and oxaliplatin was administered at 50 mg/m2 on days 1, 8, 22, and 29."2.73Multicenter phase II trial of chemoradiation with oxaliplatin for rectal cancer. ( Arnold, D; Bieker, M; Ewald, H; Flentje, M; Fürst, A; Haier, J; Hellmich, G; Hermann, RM; Hipp, M; Hohenberger, W; Liersch, T; Lordick, F; Reese, T; Rödel, C; Sauer, R; Schwella, N; Sülberg, H, 2007)
"Forty patients with rectal cancer (T3-T4, and/or N+, endorectal ultrasound) received preoperative radiotherapy (1."2.73Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer. ( Aydin, S; Bonny, MA; Canon, JL; Coche, JC; Coster, B; Daisne, JF; Duck, L; Haustermans, K; Honhon, B; Humblet, Y; Kartheuser, A; Kerger, J; Kirkove, C; Laurent, S; Machiels, JP; Peeters, M; Roels, S; Scalliet, P; Sempoux, C; Van Cutsem, E, 2007)
"We sought to evaluate the efficacy and safety data of a combination regimen using weekly irinotecan in combination with capecitabine and concurrent radiotherapy (CapIri-RT) as neoadjuvant treatment in rectal cancer in a phase-II trial."2.73A phase II study of capecitabine and irinotecan in combination with concurrent pelvic radiotherapy (CapIri-RT) as neoadjuvant treatment of locally advanced rectal cancer. ( Grobholz, R; Hochhaus, A; Hofheinz, RD; Horisberger, K; Kähler, G; Kraus-Tiefenbacher, U; Leitner, A; Post, S; Wenz, F; Willeke, F; Willer, A, 2007)
"Capecitabine was given orally 825 mg/m(2) twice daily for 7 days each week during RT."2.73Phase I trial of preoperative hypofractionated intensity-modulated radiotherapy with incorporated boost and oral capecitabine in locally advanced rectal cancer. ( Callahan, E; Cheng, J; Cohen, S; Freedman, GM; Hoffman, J; Konski, A; Lewis, N; Meropol, NJ; Price, R; Rogatko, A; Sigurdson, ER; Watkins-Bruner, D, 2007)
" This study was to evaluate the efficacy of FOLFOX6 regimen on Chinese colorectal cancer patients with liver metastasis, and observe the adverse events."2.73[Efficacy and toxicity of FOLFOX6 regimen in treating colorectal cancer patients with liver metastasis]. ( Chen, G; Ding, PR; Fang, YJ; Li, LR; Lu, ZH; Pan, ZZ; Wan, DS; Wang, GQ; Wu, XJ; Zhou, ZW, 2007)
" In locally advanced rectal cancer, preoperative infusional chemotherapy combined with radiation was found to be less toxic than bolus chemotherapy and radiotherapy."2.73Differences in toxicity across gender in patients treated with chemoradiation for rectal cancer. ( Elsaleh, H; Joseph, D; Kaminski, A, 2007)
"Ninety patients with metastatic colorectal cancer were included in the study."2.73TIMP-1 is significantly associated with objective response and survival in metastatic colorectal cancer patients receiving combination of irinotecan, 5-fluorouracil, and folinic acid. ( Berglund, A; Brünner, N; Byström, P; Christensen, IJ; Glimelius, B; Nielsen, HJ; Sørensen, NM, 2007)
"T3-4 rectal cancer patients received escalating doses of oxaliplatin (day 1 and 29) with a fixed dose of capecitabine of 1000 mg/m(2) twice daily (days 1-14, 25-38) added to RT with 50."2.73Preoperative chemoradiotherapy with capecitabine and oxaliplatin in locally advanced rectal cancer. A phase I-II multicenter study of the Dutch Colorectal Cancer Group. ( Cats, A; Havenga, K; Hospers, GA; Jansen, EP; Leer, JW; Marijnen, CA; Mulder, NH; Punt, CJ; Tesselaar, ME; Van de Velde, CJ; Van Krieken, HH; Wiggers, T, 2007)
"A total of 60 patients with rectal cancer (T3-T4 or N+, M1 allowed) entered the trial at five investigator sites; the data from 58 patients were assessable."2.73Phase I-II trial of cetuximab, capecitabine, oxaliplatin, and radiotherapy as preoperative treatment in rectal cancer. ( Arnold, D; Dellas, K; Hermann, RM; Hinke, A; Hipp, M; Hohenberger, W; Iesalnieks, I; Liersch, T; Lordick, F; Rödel, C; Sauer, R, 2008)
"Capecitabine was given at a dose of 900 mg m(-2) for 5 days per week combined with 45 Gy of radiotherapy in 25 doses."2.73Preoperative radiotherapy combined with 5 days per week capecitabine chemotherapy in locally advanced rectal cancer. ( Byrne, P; Cooper, R; Craven, I; Crellin, A; Melcher, A; Sebag-Montefiore, D, 2007)
"Chemoradiotherapy of the last phase II study with intermittent capecitabine (1500 mg/m(2)/day, delivered on days 1-14 and 22-35) and irinotecan (4 x 60 mg/m(2)) concurrently to radiotherapy is a safe treatment with low toxicity and high efficacy."2.73Intensified irinotecan-based neoadjuvant chemoradiotherapy in rectal cancer: four consecutive designed studies to minimize acute toxicity and to optimize efficacy measured by pathologic complete response. ( Fietkau, R; Foitzik, T; Klar, E; Klautke, G; Küchenmeister, U; Ludwig, K; Prall, F; Semrau, S, 2007)
"Patients with rectal T3-T4 and/or N0-N+ rectal cancer received capecitabine 825 mg/m(2) twice daily Monday through Friday and oxaliplatin 60 mg/m(2) intravenously on Days 1, 8, and 15, concurrently with intensity-modulated radiotherapy."2.73Phase I-II trial of concurrent capecitabine and oxaliplatin with preoperative intensity-modulated radiotherapy in patients with locally advanced rectal cancer. ( Arbea, L; Aristu, JJ; Azcona, JD; Díaz-González, JA; García-Foncillas, JM; Hernández-Lizoain, JL; Martínez-Monge, R; Moreno, M; Rodriguez, J; Sola, JJ, 2008)
"At surgery, the Rectal Cancer Regression Grade (RCRG) was registered."2.73Integrating microarray and proteomics data to predict the response on cetuximab in patients with rectal cancer. ( Daemen, A; De Bie, T; De Moor, B; Debucquoy, A; Gevaert, O; Haustermans, K; Machiels, JP, 2008)
"Irinotecan (60 mg m(-2)) was given on days 1, 8, 15 and 22."2.73Irinotecan+5-fluorouracil with concomitant pre-operative radiotherapy in locally advanced non-resectable rectal cancer: a phase I/II study. ( Biswas, A; Gollins, S; Haylock, B; Iles, S; Levine, E; Myint, S; Susnerwala, S; Swindell, R, 2008)
"A Phase I study was conducted to determine the maximal tolerated dose and the dose-limiting toxicity (DLT) of oxaliplatin (OXA) combined with capecitabine and radiotherapy as adjuvant treatment in patients with operable rectal cancer."2.73Phase I study of oxaliplatin in combination with capecitabine and radiotherapy as postoperative treatment for stage II and III rectal cancer. ( Fang, H; Jin, J; Li, YX; Liu, YP; Wang, JW; Wang, K; Wang, WH; Yu, ZH; Zhou, AP; Zhou, ZX, 2008)
"These tumours are assessed as rectal cancer using immunohistochemical and radiological tests, and certain criteria (localisation, relationship with neighbouring structures) have to be fulfilled to make the diagnosis."2.72Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations. ( Astaras, C; Bornand, A; Koessler, T, 2021)
"Capecitabine was administered concurrently with RT in escalating doses, twice daily with a 12-h interval, for two cycles of 14 days separated by a 7-day rest."2.72A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer. ( Jin, J; Li, N; Li, T; Li, YX; Liu, XF; Liu, YP; Song, YW; Wang, WH; Yu, ZH, 2006)
"The aim of the study was to evaluate tolerance and efficacy of preoperative treatment with capecitabine in combination with radiation therapy (RT) in patients with locally advanced, resectable, rectal cancer."2.72Capecitabine in combination with preoperative radiation therapy in locally advanced, resectable, rectal cancer: a multicentric phase II study. ( Beretta, GD; Chiara, S; Corvò, R; De Paoli, A; Del Prete, S; Friso, ML; Frustaci, S; Innocente, R; Luppi, G; Mantello, G; Pasetto, L; Rosso, R; Santantonio, M; Sarti, E, 2006)
"Patients with clinically unresectable rectal cancer or for whom resection with histologically clear (R0) surgical margins was unlikely received continuous capecitabine (500-825 mg/m2 twice daily, 7 days/week), oxaliplatin 2-h intravenous infusion (130 mg/m2 days 1 and 29) and pelvic radiotherapy (Monday-Friday for 5 weeks, total dose 45 Gy in 25 daily 1."2.72A phase I dose escalation study of continuous oral capecitabine in combination with oxaliplatin and pelvic radiation (XELOX-RT) in patients with locally advanced rectal cancer. ( Falk, SJ; Glynne-Jones, R; Maughan, TS; McDonald, AC; Sebag-Montefiore, D, 2006)
"7%); previous radiotherapy dosage ranged between 30 and 55 Gy (median, 50."2.72Preoperative hyperfractionated chemoradiation for locally recurrent rectal cancer in patients previously irradiated to the pelvis: A multicentric phase II study. ( Bolzicco, G; Coco, C; Dalla Palma, M; De Paoli, A; Di Russo, A; Doglietto, GB; Gambacorta, MA; Mohiuddin, M; Morganti, AG; Rossi, C; Valentini, V; Valvo, F, 2006)
"Patients with clinical T3/T4 distal rectal cancers were randomly assigned in a phase II study to receive combined neoadjuvant chemoradiotherapy followed by surgical resection."2.72Randomized phase II study of neoadjuvant combined-modality chemoradiation for distal rectal cancer: Radiation Therapy Oncology Group Trial 0012. ( Hanna, N; Hayostek, C; Mitchell, E; Mohiuddin, M; Nichols, C; Shane, R; Willett, C; Winter, K; Yuen, A, 2006)
"Capecitabine and gefitinib were administered throughout the radiation course."2.72Increased toxicity with gefitinib, capecitabine, and radiation therapy in pancreatic and rectal cancer: phase I trial results. ( Bendell, JC; Blobe, GC; Clary, BM; Czito, BG; Fernando, NH; Honeycutt, W; Hurwitz, HI; Ludwig, KA; Mantyh, CR; Morse, MA; Pappas, TN; Tyler, DS; Willett, CG; Yu, D, 2006)
"MRI criteria for poor-risk rectal cancer were tumors within 1 mm of mesorectal fascia (ie, circumferential resection margin threatened), T3 tumors at or below levators, tumors extending > or = 5 mm into perirectal fat, T4 tumors, and T1-4N2 tumors."2.72Neoadjuvant capecitabine and oxaliplatin followed by synchronous chemoradiation and total mesorectal excision in magnetic resonance imaging-defined poor-risk rectal cancer. ( Brown, G; Chau, I; Cunningham, D; Hill, M; Massey, A; Norman, AR; Oates, J; Ross, PJ; Tait, D; Tebbutt, N; Wotherspoon, A, 2006)
"Approximately 1 out of 10 advanced rectal cancers after preoperative radiotherapy or radiochemotherapy was characterized by DIS of over 5 mm."2.72Distal intramural spread of rectal cancer after preoperative radiotherapy: the results of a multicenter randomized clinical study. ( Bujko, K; Chmielik, E; Huzarski, T; Karmolinski, A; Kepka, L; Majewski, P; Nasierowska-Guttmejer, A; Nowacki, MP; Sopylo, R; Sygut, J; Wandzel, P; Wojnar, A, 2006)
"To investigate the effect of three-dimensional conformal radiotherapy (3-DCRT) in combination with FOLFOX4 chemotherapy for unresectable recurrent rectal cancer."2.72Three-dimensional conformal radiotherapy combined with FOLFOX4 chemotherapy for unresectable recurrent rectal cancer. ( He, C; Hu, JB; Sun, XN; Wang, Q; Xu, J; Yang, QC, 2006)
"Capecitabine was given orally twice daily Monday through Friday concurrently with RT."2.72A Phase I study of weekly intravenous oxaliplatin in combination with oral daily capecitabine and radiation therapy in the neoadjuvant treatment of rectal adenocarcinoma. ( Fakih, MG; Lawrence, DD; Pendyala, L; Rajput, A; Rustum, YM; Smith, JL; Toth, K; Yang, GY, 2006)
" CPT-11 (50 mg/m(2) weekly) and 5-FU (225 mg/m(2)/day continuous infusion, 5 days/week) were concurrently administered with radiation therapy (RT) (45 Gy, 1."2.72A Phase II study of preoperative radiotherapy and concomitant weekly irinotecan in combination with protracted venous infusion 5-fluorouracil, for resectable locally advanced rectal cancer. ( Aranda, E; Cervantes, A; Dotor, E; Gallén, M; García, JL; Navarro, M; Rivera, F; Sánchez-Rovira, P; Vega-Villegas, ME, 2006)
"One hundred and thirteen patients with rectal cancer were randomly classified into 2 groups."2.72[Chemoembolization of bilateral internal iliac arteries in Miles operation]. ( Hao, SH; Liu, FL, 2006)
"Some rectal cancers respond well to preoperative neoadjuvant therapy while others are inherently resistant or develop resistance during the treatment."2.72Molecular responses of rectal cancer to preoperative chemoradiation. ( Debucquoy, A; Geboes, K; Goethals, L; Haustermans, K; Mc Bride, WH; Roels, S, 2006)
"4 Gy/28 fractions) combined with 5-FU (200-225 mg/m(2)/day by continuous venous infusion) and weekly OXA (25-60 mg/m(2))."2.725-fluorouracil and weekly oxaliplatin combined with radiotherapy for locally advanced rectal cancer: surgical complications and long-term results. ( Aschele, C; Bruttocao, A; DeSalvo, GL; Fabris, G; Ferraro, B; Finco, C; Frego, M; Friso, ML; Lise, M; Lonardi, S; Nitti, D; Pucciarelli, S; Rugge, M; Toppan, P; Urso, E, 2006)
"In patients with rectal cancer who receive preoperative radiotherapy, adding fluorouracil-based chemotherapy preoperatively or postoperatively has no significant effect on survival."2.72Chemotherapy with preoperative radiotherapy in rectal cancer. ( Bardet, E; Beny, A; Bosset, JF; Calais, G; Collette, L; Daban, A; Maingon, P; Mineur, L; Ollier, JC; Radosevic-Jelic, L, 2006)
"Twenty patients with rectal cancer (clinical Stage uT3-T4 or N+) received a standard dosing regimen of cetuximab (400 mg/m(2) on Day 1 and 250 mg/m(2) on Days 8, 15, 22, and 29) and escalating doses of irinotecan and capecitabine according to phase I methods: dose level I, irinotecan 40 mg/m(2) on Days 1, 8, 15, 22, and 29 and capecitabine 800 mg/m(2) on Days 1-38; dose level II, irinotecan 40 mg/m(2) and capecitabine 1000 mg/m(2); and dose level III, irinotecan 50 mg/m(2) and capecitabine 1000 mg/m(2)."2.72Phase I trial of cetuximab in combination with capecitabine, weekly irinotecan, and radiotherapy as neoadjuvant therapy for rectal cancer. ( Dinter, D; Grobholz, R; Heeger, S; Hochhaus, A; Hofheinz, RD; Horisberger, K; Kähler, G; Kraus-Tiefenbacher, U; Post, S; Wenz, F; Willeke, F; Woernle, C, 2006)
"The 5-year incidence of local recurrence was lower with chemoradiotherapy (8."2.72Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203. ( Bedenne, L; Bonnetain, F; Bouché, O; Buecher, B; Chapet, O; Closon-Dejardin, MT; Conroy, T; Ducreux, M; Francois, E; Gérard, JP; Leduc, B; Mackiewicz, R; Maurel, J; Seitz, JF; Untereiner, M, 2006)
"Capecitabine was orally administered concurrently with radiotherapy for a total of 2 cycles in escalating doses: twice daily at 12 hour interval for consecutive 14 days as one cycle, separated by a seven day rest, then followed by another cycle."2.72[Phase I study of postoperative concurrent chemoradiation with capecitabine as adjuvant treatment for stage II/III operable rectal cancer]. ( Jin, J; Li, N; Li, T; Li, YX; Liu, YP; Song, YW; Wang, WH, 2006)
") bolus, days 1-5) plus LEV (150 mg/day orally, days 1-3); postoperative RT was delivered during week 2 at the same dosage and schedule as in arm I."2.71Randomised clinical trial of adjuvant postoperative RT vs. sequential postoperative RT plus 5-FU and levamisole in patients with stage II-III resectable rectal cancer: a final report. ( Cafiero, F; Gipponi, M; Lionetto, R, 2003)
"Peripheral lymphocytes of twelve rectal cancer patients who had undergone postoperative radiochemotherapy 2-3 years ago were investigated for residual chromosomal damage using 24-color fluorescence in situ hybridization (24-color FISH)."2.71Residual chromosomal damage after radiochemotherapy with and without amifostine detected by 24-color FISH. ( Claussen, U; Dreidax, M; Dunst, J; Kuechler, A; Liehr, T; Pigorsch, SU; Wendt, TG, 2003)
"Capecitabine was administered twice daily in escalating doses during the entire period of RT."2.71Multicenter dose-finding study of concurrent capecitabine and radiotherapy as adjuvant treatment for operable rectal cancer. ( Androulakis, N; Ardavanis, A; Georgoulias, V; Kakolyris, S; Kalbakis, K; Kourousis, C; Mavroudis, D; Pallis, A; Souglakos, J; Vardakis, N; Varveris, C, 2003)
"Capecitabine was administered concurrently at 825 mg/m2 bid on days 1 to 14 and 22 to 35, with oxaliplatin starting at 50 mg/m2 on days 1, 8, 22, and 29 with planned escalation steps of 10 mg/m2."2.71Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer. ( Grabenbauer, GG; Hohenberger, W; Papadopoulos, T; Rödel, C; Sauer, R; Schmoll, HJ, 2003)
"Patients with locally advanced operable rectal cancer (uT3/4 or uN+, Mason CS III/IV) were randomly assigned to pre or postoperative RCT: A total dose of 50."2.71Adjuvant vs. neoadjuvant radiochemotherapy for locally advanced rectal cancer: the German trial CAO/ARO/AIO-94. ( Becker, H; Fietkau, R; Hess, C; Hohenberger, W; Karstens, JH; Martus, P; Raab, R; Rödel, C; Sabitzer, H; Sauer, R; Tschmelitsch, J; Wittekind, C, 2003)
"Attempted surgical salvage of rectal cancer recurrence is performed commonly in the United States."2.71Analysis of surgical salvage after failure of primary therapy in rectal cancer: results from Intergroup Study 0114. ( Cooke, E; Hollis, D; Mayer, RJ; Niedzwiecki, D; O'Connell, M; Tepper, JE, 2003)
"Consenting patients with presumed colorectal cancer were randomized to surgery with or without 7 days of PVI (1 g 5-FU plus 5000 units heparin in 1 litre 5 per cent dextrose infused over each 24-h period)."2.71Randomized clinical trial of adjuvant radiotherapy and 5-fluorouracil infusion in colorectal cancer (AXIS). ( Donaldson, D; Gray, R; James, RD; Northover, JM; Stenning, SP; Taylor, I, 2003)
"Sixty lower rectal cancer patients were divided randomly into two groups."2.71[Combined preoperative xeloda and radiotherapy for lower rectal cancer]. ( Cai, GY; Li, TH; Wu, JW; Zhuang, CP, 2003)
"Eniluracil and 5-FU were given with a 5-week course of preoperative radiotherapy of 4500 cGy, with a possible 540-cGy boost."2.71A Phase I trial of preoperative eniluracil plus 5-fluorouracil and radiation for locally advanced or unresectable adenocarcinoma of the rectum and colon. ( Anscher, MS; Cohen, DP; Czito, BG; Ertel, PJ; Honeycutt, W; Hong, TJ; Hurwitz, HI; Lee, CG; Lockhart, AC; Ludwig, KA; Mangum, SG; Mantyh, C; Morse, MA; Petros, WP; Seigler, HF; Spector, NL; Tyler, DS, 2004)
"The purpose of our study was to determine the maximum-tolerated dose, dose-limiting toxicity, safety profile, and pharmacokinetics of the polyamine synthesis inhibitor SAM486A given in combination with 5-fluorouracil/leucovorin (5-FU/LV) in cancer patients."2.71Phase I and pharmacokinetic study of the polyamine synthesis inhibitor SAM486A in combination with 5-fluorouracil/leucovorin in metastatic colorectal cancer. ( Bootle, D; Bridgewater, J; Choi, L; de Bruijn, P; Eskens, FA; Ledermann, JA; Mueller, C; Planting, AS; Sklenar, I; Sparreboom, A; van Zuylen, L; Verweij, J, 2004)
"Preoperative chemoradiotherapy in rectal cancer using chronomodulated 5-FU and LV is feasible."2.71Phase I study of 5-fluorouracil and leucovorin by continuous infusion chronotherapy and pelvic radiotherapy in patients with locally advanced or recurrent rectal cancer. ( Berry, S; Bjarnason, GA; Davey, P; de Marsh, RW; Mendenhall, W; Parulekar, W; Rout, WR; Wong, R; Zlotecki, R, 2004)
"A total of 760 patients with colon cancer and 669 patients with rectal cancer were entered into this randomized clinical trial (RCT)."2.71Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu ( Hojyo, K; Isomoto, H; Kato, T; Kodaira, S; Kunii, Y; Kunitomo, K; Niimoto, M; Nishida, O; Ohashi, Y; Takahashi, T; Tominaga, T; Watanabe, M; Yasutomi, M, 2004)
"For patients with resectable rectal cancer receiving concurrent, full dose radiotherapy, the recommended dose of capecitabine for further study is 1800 mg m(-2) day(-1) when given in this schedule."2.71A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer. ( Leong, T; Lim Joon, D; Mackay, J; McKendrick, J; Michael, M; Ngan, SY; Zalcberg, JR, 2004)
" We assessed the feasibility and pharmacokinetic interactions of combining MMI270 with 5-fluorouracil (5-FU) and folinic acid (FA)."2.71A dose-finding and pharmacokinetic study of the matrix metalloproteinase inhibitor MMI270 (previously termed CGS27023A) with 5-FU and folinic acid. ( Blackey, R; Cassidy, J; Choi, L; Devlin, M; Eatock, M; Johnson, J; Morrison, R; Owen, S; Twelves, C, 2005)
"To establish the feasibility and efficacy of capecitabine in combination with weekly irinotecan (CAPIRI) with concurrent pelvic radiotherapy (RT) in patients with locally advanced rectal cancer."2.71Phase I trial of capecitabine and weekly irinotecan in combination with radiotherapy for neoadjuvant therapy of rectal cancer. ( Gnad, U; Hehlmann, R; Hochhaus, A; Hofheinz, RD; Kraus-Tiefenbacher, U; Müldner, A; Post, S; von Gerstenberg-Helldorf, B; Wenz, F; Willeke, F, 2005)
"The aim of this study was to define the recommended dose of oxaliplatin when combined with infusional 5-fluorouracil (5-FU) and concurrent pelvic radiotherapy."2.71Oxaliplatin combined with infusional 5-fluorouracil and concomitant radiotherapy in inoperable and metastatic rectal cancer: a phase I trial. ( Hicks, RJ; Leong, T; Lim-Joon, D; Loi, S; Mackay, J; Michael, M; Mitchell, P; Mukesh, B; Ngan, SY; Rischin, D; Zalcberg, J, 2005)
"Capecitabine is an attractive radiosensitizer which can be tumor specific."2.71Preoperative concurrent radiotherapy with capecitabine before total mesorectal excision in locally advanced rectal cancer. ( Ahn, SD; Chang, HM; Choi, EK; Kim, HC; Kim, JC; Kim, JH; Kim, JS; Kim, TW; Lee, SW; Park, JH; Ryu, MH; Shin, SS; Yu, CS, 2005)
"In patients with rectal cancer, preliminary results of EORTC Trial 22921 indicate that the addition of CT to preop RT induces down-sizing, downstaging, and significant changes in histologic characteristics."2.71Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921. ( Bardet, E; Beny, A; Bosset, JF; Briffaux, A; Calais, G; Collette, L; Daban, A; Maingon, P; Mineur, L; Radosevic-Jelic, L, 2005)
"Forty patients with rectal cancer (T3-T4 and/or N+) received radiotherapy (1."2.71Phase II study of preoperative oxaliplatin, capecitabine and external beam radiotherapy in patients with rectal cancer: the RadiOxCape study. ( Aydin, S; Baurain, JF; Canon, JL; Coche, JC; Coster, B; Duck, L; Gilbeau, L; Honhon, B; Humblet, Y; Kartheuser, A; Kerger, J; Kirkove, C; Laurent, S; Machiels, JP; Octave-Prignot, M; Remouchamps, V; Scalliet, P; Sempoux, C; Van Maele, P, 2005)
"For patients with rectal cancer treated with full thickness local excision the risk of mesorectal nodal metastases has to be very low."2.71Prediction of mesorectal nodal metastases after chemoradiation for rectal cancer: results of a randomised trial: implication for subsequent local excision. ( Bujko, K; Kepka, L; Nasierowska-Guttmejer, A; Nowacki, MP; Oledzki, J; Rogowska, D; Serkies, K; Stryczyńska, G; Suwiński, R; Tokar, P; Wieczorek, A; Winkler-Spytkowska, B, 2005)
" The initial weekly oxaliplatin dosage was 30 mg/m2 and the 5FU dosage 150 mg/m2/d."2.71Combined radiotherapy, 5-fluorouracil continuous infusion and weekly oxaliplatin in advanced rectal cancer: a phase I study. ( Bertheault-Cvitkovic, F; Conroy, T; Ducreux, M; François, E; Giovannini, M; Lemanski, C; Magnin, V; Thomas, O; Ychou, M, 2005)
"Capecitabine was administered at escalating doses from 250 to 1,250 mg/m(2) bid (including weekends) for the duration of radiotherapy."2.70Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer. ( Dunst, J; Frings, S; Hinke, A; Kölling-Schlebusch, K; Reese, T; Sutter, T; Zühlke, H, 2002)
"Twenty-eight patients with rectal cancer, staged as over T3N1 or T4 by transrectal ultrasonography between July 1997 and December 1998, were included in this study."2.70Intravenous 5-fluorouracil versus oral doxifluridine as preoperative concurrent chemoradiation for locally advanced rectal cancer: prospective randomized trials. ( Jung, HC; Kim, NK; Min, JS; Park, JK; Roh, JK; Sung, JS; Yun, SH, 2001)
"The aim of this study was to examine the efficacy and safety of both oxaliplatin as a single agent and oxaliplatin in combination with dailyx5 bolus 5-fluorouracil and folinic acid (5-FU/FA, Mayo clinic regimen) in the first-line treatment of metastatic colorectal cancer (CRC) patients."2.70A randomised phase II study of oxaliplatin alone versus oxaliplatin combined with 5-fluorouracil and folinic acid (Mayo Clinic regimen) in previously untreated metastatic colorectal cancer patients. ( Balbiani, L; Bella, S; Blajman, C; Cazap, E; Chacón, M; Cóppola, F; Giglio, R; Lastiri, F; Mickiewicz, E; Montiel, M; Perazzo, F; Pujol, F; Recondo, G; Richardet, E; Rodger, J; Schmilovich, A; Simon, J; Van Kooten, M; Vilanova, M; Wasserman, E; Zori Comba, A, 2001)
"Patients with locally advanced operable rectal cancer (uT3/4 or uN+, Mason CS III/IV) were randomly assigned to pre- or postoperative radiochemotherapy: A total dose of 50."2.70Adjuvant versus neoadjuvant radiochemotherapy for locally advanced rectal cancer. A progress report of a phase-III randomized trial (protocol CAO/ARO/AIO-94). ( Becker, H; Fietkau, R; Hess, C; Hohenberger, W; Jatzko, G; Karstens, JH; Martus, P; Raab, R; Rödel, C; Sabitzer, H; Sauer, R; Wittekind, C, 2001)
"Patients with stage II and III rectal cancer received weekly 2-hour infusions of FA 500 mg/m2 followed by continuous 24-hour infusions of 5-FU 2,600 mg/m2 postoperatively via a Port-A-Cath system."2.70Adjuvant radio-chemotherapy in stage II-III rectal cancer with 24-hour infusion of high-dose 5-fluorouracil and folinic acid: evaluation of feasibility. ( Bambach, M; Dencausse, Y; Dietzler, P; Edler, L; Hartung, G; Lindemann, H; Qeisser, W; Sturm, J; Wojatschek, C, 2001)
" Both before and after the addition of OXA, the 5-FU dose was individually adjusted according to the pharmacokinetic follow-up (target steady-state plasma concentrations 2."2.70Influence of oxaliplatin on 5-fluorouracil plasma clearance and clinical consequences. ( Boisdron-Celle, M; Brienza, S; Craipeau, C; Cvitkovic, E; Delva, R; Gamelin, E; Guérin-Meyer, V, 2002)
"Exclusive CRT approach is not safe to treat patients with low infiltrative rectal carcinoma."2.70Chemoradiation instead of surgery to treat mid and low rectal tumors: is it safe? ( David Filho, WJ; de O Ferreira, F; Ferrigno, R; Lopes, A; Nakagawa, WT; Nishimoto, IN; Rossi, BM; Vieira, RA, 2002)
" In a previous study with 5-FU stepwise dose escalation in a weekly regimen, and pharmacokinetic monitoring, we defined a therapeutic range for 5-FU plasma levels: 2,000 to 3,000 microg/L (area under the concentration-time curve at 0 to 8 hours [AUC0-8], 16 to 24 mg x h/L)."2.69Long-term weekly treatment of colorectal metastatic cancer with fluorouracil and leucovorin: results of a multicentric prospective trial of fluorouracil dosage optimization by pharmacokinetic monitoring in 152 patients. ( Alleaume, C; Boisdron-Celle, M; Burtin, P; Cailleux, PE; Danquechin-Dorval, E; Delva, R; Dumesnil, Y; Fety, R; Gamelin, E; Geslin, J; Gesta, P; Goudier, MJ; Larra, F; Lortholary, A; Maigre, M; Maillart, P; Maillet, ML; Person-Joly, MC; Picon, L; Regimbeau, C; Robert, J; Sire, M, 1998)
" However, these results cannot eliminate a small benefit when PVI is used at a higher dosage or in combination with mitomycin."2.69Adjuvant portal-vein infusion of fluorouracil and heparin in colorectal cancer: a randomised trial. European Organisation for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group, the Gruppo Interdisciplinare Valutazione Interv ( Apolone, G; Couvreur, ML; Curran, D; De Waele, B; Doci, R; Labianca, R; Lasser, P; Marsoni, S; Nakajima, T; Nitti, D; Pector, JC; Rauschecker, H; Rougier, P; Sahmoud, T; Wils, J, 1998)
" We administered pharmacokinetic modulating chemotherapy, based on the concept that the benefit of a continuous venous 5-fluorouracil (5FU) infusion can be potentiated by low-dose oral UFT, a combination of 1-(2-tetrahydrofuryl)-5-fluorouracil (tegafur) and uracil at a molar ratio of 1:4."2.69Effects of pharmacokinetic modulating chemotherapy using oral UFT and continuous venous 5FU infusion on the prognosis of irradiated rectal carcinomas with p53 overexpression. ( Kotera, H; Kusunoki, M; Noda, M; Yamamura, T; Yanagi, H, 1998)
"A total of 48 patients suffering from rectum cancer were included in this randomized study conducted at the Proctology Department of the Donetsk Regional Anti-Cancer Center."2.69Comparative evaluation of the complex treatment of rectal cancer patients (chemotherapy and X-ray therapy, Ukrain monotherapy). ( Bondar, GV; Borota, AV; Yakovets, YI; Zolotukhin, SE, 1998)
"All patients had metastatic colorectal cancer, with adjuvant or palliative chemotherapy given to six patients (22%) on schedule A and 12 patients on schedule B (41%)."2.69Continuous delivery of venous 5-fluorouracil and arterial 5-fluorodeoxyuridine for hepatic metastases from colorectal cancer: feasibility and tolerance in a randomized phase II trial comparing flat versus chronomodulated infusion. ( Adam, R; Bismuth, H; Dallemagne, B; Focan, C; Focan-Henrard, D; Jasmin, C; Jehaes, C; Kreutz, F; Levi, F; Lobelle, JP; Markiewicz, S; Misset, JL; Weerts, J, 1999)
"Median times to disease progression for the three treatment arms were as follows: 9."2.69Randomized, multicenter trial of fluorouracil plus leucovorin administered either via hepatic arterial or intravenous infusion versus fluorodeoxyuridine administered via hepatic arterial infusion in patients with nonresectable liver metastases from colore ( Lorenz, M; Müller, HH, 2000)
"Standard adjuvant chemotherapy for colorectal cancer consists of fluorouracil with folinic acid or levamisole."2.69Comparison of fluorouracil with additional levamisole, higher-dose folinic acid, or both, as adjuvant chemotherapy for colorectal cancer: a randomised trial. QUASAR Collaborative Group. ( , 2000)
" A dose-response relationship was observed between the radiation dose and the tumor downstaging and local control."2.69Preoperative chemotherapy and pelvic radiation for tethered or fixed rectal cancer: a phase II dose escalation study. ( Buie, D; Chan, AK; Heine, J; Jenken, D; Johnson, DR; Langevin, J; Wong, AO, 2000)
" 5-FU chemotherapy was administered as 120-hours continuous infusion in the first and fifth radiation week via a central venous catheter in a daily dosage of 1,000 mg/m2."2.69Intermittent use of amifostine during postoperative radiochemotherapy and acute toxicity in rectal cancer patients. ( Dunst, J; Müller, AC; Pigorsch, S; Reese, T; Semlin, S, 2000)
" Patients in arm II began with 5-FU (450 mg/m(2)/day intravenous bolus, days 1-5) plus levamisole (150 mg/day orally, days 1-3); postoperative RT was delivered during week 2 at the same dosage and schedule as in arm I."2.69Preliminary analysis of a randomized clinical trial of adjuvant postoperative RT vs. postoperative RT plus 5-FU and levamisole in patients with TNM stage II-III resectable rectal cancer. ( Bertoglio, S; Cafiero, F; Gipponi, M; Lionetto, R; Peressini, A, 2000)
"In locally advanced rectal cancer tumor-negative margins often cannot be obtained by surgery alone."2.69[First results of neoadjuvant simultaneious radiochemotherapy in advanced rectal carcinoma]. ( Fietkau, R; Hopt, UT; Kirchner, R; Klautke, G; Küchenmeister, U; Mellert, J; Mücke, R, 2000)
"The regimens for colon cancer were, Arm I: mitomycin C [intraoperative portal vein bolus (12 mg/m2) + postoperative, twice weekly and then three times bimonthly for six months intermittent i."2.68Five-year results of a randomized controlled trial of adjuvant chemotherapy for curatively resected colorectal carcinoma. The Colorectal Cancer Chemotherapy Study Group of Japan. ( , 1995)
"Twenty patients with non-resectable rectal cancer (Mason CS III-IV) have been irradiated from September 1989 through February 1994."2.68[Preoperative radiochemotherapy in primary non-resectable rectal cancer]. ( Dunst, J; Dworak, O; Keilholz, L; Köckerling, F; Sauer, R; Schwarz, B, 1995)
"Thirty-five patients with rectal cancer underwent surgery after this treatment, and 41 patients underwent surgery without pretreatment."2.68Prognostic evaluation of preoperative combined treatment for advanced cancer in the lower rectum with radiation, intraluminal hyperthermia, and 5-fluorouracil suppository. ( Ichikawa, D; Sawai, K; Takahashi, T; Yamaguchi, T; Yoshioka, Y, 1996)
"5-FU; and arm III was surgery only."2.68Prognostic factors of colorectal cancer. Results of multivariate analysis of curative resection cases with or without adjuvant chemotherapy. ( Hamano, K; Kato, T; Kodaira, S; Koyama, Y; Ogawa, N; Sakabe, T; Takahashi, T; Tominaga, T; Yasutomi, M, 1996)
" However, the combined therapy is associated with more toxic effects, raising the question of whether the benefits of the treatment justify its quality-of-life costs for the individual patient."2.68A quality-adjusted time without symptoms or toxicity (Q-TWiST) analysis of adjuvant radiation therapy and chemotherapy for resectable rectal cancer. ( Cole, BF; Gelber, RD; Goldhirsch, A; Krook, JE; Schroeder, G; Wieand, HS, 1996)
"Distant metastases occurred in two high-risk patients and in eight patients with a locally advanced tumor."2.68Intraoperative radiation therapy in integrated treatment of rectal cancers. Results of phase II study. ( Bellantone, R; Bossola, M; Cellini, N; Crucitti, F; Doglietto, GB; Ippoliti, M; Merico, M; Nucera, P; Ratto, C; Sofo, L; Trodella, L; Valentini, V, 1996)
" Laboratory studies of IFN-beta suggest that this agent may offer theoretical advantages over IFN-alpha in combination with 5-FU."2.68A phase II study of recombinant interferon-beta (r-hIFN-beta 1a) in combination with 5-fluorouracil (5-FU) in the treatment of patients with advanced colorectal carcinoma. ( Bradley, C; Hallam, S; Illingworth, JM; Joffe, JK; Perren, TJ; Primrose, J; Selby, PJ; Ward, U, 1997)
"Patients with rectal cancer of stage dukes B and C were randomized into two groups."2.68[Preoperative intraluminal 5-FU osmosis chemotherapy as an adjuvant to radical resection for rectal cancer]. ( Liu, L; Lu, J; Zhao, L, 1996)
"Resection of colorectal cancer and portal infusion of adjuvant chemotherapy."2.68Association between blood transfusion and survival in a randomised multicentre trial of perioperative adjuvant portal chemotherapy in patients with colorectal cancer. The Swiss Group for Clinical Cancer Research (SAKK). ( , 1997)
"Some 978 patients with colon cancer and 713 patients with rectal cancer were enrolled in the study, 85 (5."2.68[Prospective controlled study on the usefulness of Carmofur as a postoperative adjuvant chemotherapy for colorectal cancer]. ( Hojo, K; Ichihashi, H; Kato, T; Kikuchi, K; Kodaira, S; Kunii, Y; Ogawa, M; Takahashi, T; Tamada, R; Tominaga, T; Yasutomi, M, 1997)
"In advanced colorectal cancer the addition of folinic acid (FA) has been shown to lead to increased activity, at least in terms of response rate, in comparison with 5-fluorouracil (5FU) alone."2.67Double modulation of 5-fluorouracil in advanced colorectal cancer with low-dose interferon-alpha 2b and folinic acid. The "GISCAD" experience. Italian Group for the Study of Digestive Tract Cancer. ( Ambrosini, G; Barni, S; Duro, M; Fiorentini, G; Giaccon, G; Iirillo, A; Labianca, R; Oliani, C; Pancera, G; Piazza, E, 1994)
" Treatment was well tolerated; 4/27 patients experienced > or = ECOG grade 3 toxicity at full 5-FU dosage (500 mg/m2 bolus/infusion)."2.67A phase I-II study of N-(phosphonacetyl)-L-aspartic acid (PALA) added to 5-fluorouracil and folinic acid in advanced colorectal cancer. ( Canney, PA; Cassidy, J; Jodrell, DI; Kaye, SB; Kerr, DJ; Oster, W; Steward, WP; Yosef, H, 1994)
"Fifty-seven Dukes C colorectal cancer patients were given 5-fluorouracil-interferon-alpha 2b adjuvant treatment from October 1986 to September 1990."2.675-Fluorouracil-interferon-alpha 2b adjuvant treatment of Dukes C colorectal cancer. ( Cremone, L; Espinosa, A; Faiella, F; Frasci, G; Leone, F; Monaco, M; Persico, G; Sapio, U, 1994)
"Thirty-one patients with fixed rectal cancers (stage > or = cT3) were treated with concomitant preoperative chemotherapy and high-dose radiation in an effort to improve resectability."2.67Downstaging of advanced rectal cancer following combined preoperative chemotherapy and high dose radiation. ( Brodovsky, H; Chen, ET; Fishbein, G; Marks, G; Mohiuddin, M, 1994)
"To create hyperthermia in rectal cancer, an intraluminal electrode connected to a radiofrequency system was devised."2.67Preoperative combined treatment with radiation, intraluminal hyperthermia, and 5-fluorouracil suppositories for patients with rectal cancer. ( Horie, H; Itoh, M; Kojima, O; Takahashi, T, 1993)
"Combined modality treatment for cancer of the rectum has been shown to reduce recurrences and improve overall survival."2.67Pelvic radiotherapy with concurrent 5-fluorouracil modulated by leucovorin for rectal cancer: a phase II study. ( Ackland, SP; Bonaventura, A; Cooper, SG; Denham, JW; Hamilton, CS; Joseph, DJ; Stewart, JF, 1993)
"Eleven patients with rectum cancer and four patients with colon cancer were treated according to the following schedule: 9 million units IFN-alpha subcutaneous three times a week; 500 mg/m2 5-FU via an intravenous bolus 1 hour after the initiation of a 2-hour infusion of 500 mg/m2 of FA, once a week."2.67Treatment of refractory colorectal carcinomas with fluorouracil, folinic acid, and interferon alfa-2a. ( Bernhard, H; Klein, O; Knuth, A; Meyer zum Büschenfelde, KH, 1992)
"Three patients with isolated liver metastases and one patient with local recurrence of rectal carcinoma received regional therapy with higher 5-FU doses."2.67Fluorouracil plus interferon + folinic acid in regional and systemic therapy in colorectal cancer. ( Preiss, J, 1992)
" The present study compared the pharmacokinetic profiles of intravenous and intra-hepatic arterial infusions of folinic acid in patients with colorectal liver metastases (n = 6) who were being treated with weekly regional infusions of 5-FU."2.67A pharmacokinetic comparison of intravenous versus intra-arterial folinic acid. ( Anderson, JH; Cooke, TG; Kerr, DJ; McArdle, CS; Setanoians, A, 1992)
"Hypotension was observed in three of five patients at the highest dose level (0."2.67A phase I trial of recombinant human interleukin-1 beta alone and in combination with myelosuppressive doses of 5-fluorouracil in patients with gastrointestinal cancer. ( Botet, J; Crown, J; Gasparetto, C; Gordon, M; Jakubowski, A; Kemeny, N; Meisenberg, B; Sheridan, C; Toner, G; Wong, G, 1991)
"The value of adjuvant chemotherapy in rectal cancer is controversial with opinions varying from 'not be used' since randomized trials have not shown significant gains to 'be used as in colon cancer' as the need is the same and colon and rectal cancers are quite similar."2.66Adjuvant chemotherapy in rectal cancer: state of the art and future perspectives. ( Glimelius, B, 2020)
"Eighty-two patients with colo-rectal cancers (29 colon and 53 rectum) were admitted and underwent radical resection from January 1982 to June 1984."2.66[Reevaluation of intraluminal fluorouracil chemotherapy as an adjuvant to radical resection of colorectal cancer--results of a randomized trial]. ( Wan, DS, 1988)
"Doxifluridine is an active agent in colorectal cancer."2.66A randomized comparison of doxifluridine and fluorouracil in colorectal carcinoma. ( Alberto, P; Cavalli, F; Germano, G; Joss, R; Kaplan, S; Martz, G; Mermillod, B; Spati, B; Weber, W, 1988)
" No serious adverse effects were observed in any of the groups."2.66[Cooperative study of surgical adjuvant chemotherapy of colorectal cancer (first report): Investigation of background factors and adverse effects. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan]. ( Abe, O; Hattori, T; Inokuchi, K; Kasai, Y; Kikuchi, K; Komi, N; Kondo, T; Kunii, Y; Ogawa, N; Taguchi, T, 1987)
"Fifty-five patients with advanced colorectal cancer were entered into a randomized controlled clinical trial to evaluate order of administration and sequential methotrexate (MTX) and 5-fluorouracil (5-FU) therapy."2.66Chemotherapy of advanced colorectal cancer. A randomized trial of sequential methotrexate and 5-fluorouracil. ( Coates, A; Mackintosh, J; Raghavan, D; Swanson, C; Tattersall, MH, 1987)
"Following curative surgery for colorectal cancer 141 patients were randomized to receive a 6 month course of 5-fluorouracil (5FU) with or without postoperative levamisole or supportive treatment only."2.66Five year results of a randomized trial of adjuvant 5-fluorouracil and levamisole in colorectal cancer. ( Bell, PR; Shaw, D; Windle, R, 1987)
"In rectosigmoid cancer the group on 5-FU included 26 patients who showed a response rate of 19% (5/26)."2.66Controlled phase III clinical study of 4-epi-doxorubicin + 5-fluorouracil versus 5-fluorouracil alone in metastatic gastric and rectosigmoid cancer. ( Kolarić, K; Potrebica, V; Stanovnik, M, 1986)
" This prospective study was undertaken to record possible adverse effects of surgery, external beam radiation therapy, and 5-fluorouracil (5-FU) chemotherapy in the treatment of large bowel cancer."2.665-Fluorouracil chemotherapy and pelvic radiation in the treatment of large bowel cancer. Decreased toxicity in combined treatment with 5-fluorouracil administration through the intraperitoneal route. ( Barofsky, I; Gianola, FJ; Hancock, SL; Sugarbaker, PH; Wesley, R, 1986)
" Alpha-2 interferon, alone or in combination with 5-FU, is ineffective in advanced colorectal cancer."2.66Two randomised phase II trials of intermittent intravenous versus subcutaneous alpha-2 interferon alone (trial 1) and in combination with 5-fluorouracil (trial 2) in advanced colorectal cancer. ( Blomgren, H; Cedermark, B; Clark, PI; Fallenius, A; Kurschel, E; Lundell, G; Niederle, N; Ohman, U; Reznek, RH; Slevin, ML, 1987)
" The mean 5-FU half-life following the high dose was nearly twice as long as that observed for the low dose (12."2.66Nonlinear pharmacokinetic characteristics of 5-fluorouracil (5-FU) in colorectal cancer patients. ( Dobbs, BR; Edwards, IR; Perrier, DG; Schaaf, LJ, 1987)
"Clinical studies were prospectively conducted to quantitate the toxic side-effects of 5-FU administered by either the intravenous (i."2.66Toxicity studies of adjuvant intravenous versus intraperitoneal 5-FU in patients with advanced primary colon or rectal cancer. ( Barofsky, I; Gianola, FJ; Meyers, CE; Sugarbaker, PH; White, DE, 1986)
"Patients with advanced colorectal cancer and no prior chemotherapy were randomized to six treatment regimens: A) fluorouracil (FU) alone; B) FU + hydroxyurea (HU); C) semustine (SE) + dacarbazine (DA); D) FU + HU alternating with SE + DA; E) SE + razoxane (RA); F) mitomycin (MI) + DA."2.65Chemotherapy of advanced colorectal carcinoma: fluorouracil alone vs. two drug combinations using fluorouracil, hydroxyurea, semustine, dacarbazine, razoxane, and mitomycin. A phase III trial by the Eastern Cooperative Oncology Group (EST: 1278). ( Engstrom, PF; Klaassen, DJ; MacIntyre, JM; Mittelman, A, 1984)
"Three hundred and eleven cases of rectal cancer received treatment according to the protocol of a cooperative randomized study."2.65[Effectiveness of combined and complex treatment of patients with operable cancer of the rectum]. ( Aliev, BM; Barsukov, IuA; Bondar', GV; Dvoĭrin, VV; Knysh, VI, 1984)
"Oral tegafur and I."2.65A comparative study of oral tegafur and intravenous 5-fluorouracil in patients with metastatic colorectal cancer. ( Bedikian, AY; Bodey, GP; Karlin, D; Korinek, J; Stroehlein, J, 1983)
"With rectal cancer, 5-year survival was 57."2.65[Evaluation of preoperative administration of N1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) suppository in surgical adjuvant chemotherapy for large bowel cancer]. ( Fujita, H; Kosaka, T; Miyazaki, I; Takashima, S; Ueno, K, 1984)
"The razoxane-treated patients experienced no significant toxicity apart from a readily reversible mild leukopenia in 52% while gastrointestinal symptoms necessitated stopping the drug in only four patients."2.65A controlled prospective trial of adjuvant razoxane in resectable colorectal cancer. ( Cassell, PC; Ellis, H; Evans, MG; Gilbert, JM; Hellmann, K; Stoodley, BJ; Wastell, C, 1981)
"Every third patient with colon cancer Dukes' C and every fourth patient with rectal cancer Dukes' C survives 5 years."2.65[Background and experience of adjuvant cytostatic therapy in gastrointestinal cancer (author's transl)]. ( Bengmark, S; Eriksson, S; Hafström, L; Hugander, A, 1981)
"Fifty-three patients with colorectal cancer Dukes' B2 and C were randomized after surgery."2.65Adjuvant therapy in colorectal cancer. (A randomized trial comparing radio-chemotherapy and radio-chemotherapy combined with the methanol extraction residue of BCG, MER). ( Bartal, A; Cohen, Y; Mekori, T; Milstein, D; Robinson, E, 1979)
"A clinical trial involving 462 colon, rectum, and breast cancer patients randomized among four different dosage regimens of 5-FU (an intravenous loading course, a weekly intravenous schedule, a nontoxic schedule, and an oral schedule) has shown a significantly better response among colon-rectum cancer patients for the intravenous loading course."2.64A phase III study comparing the clinical utility of four regimens of 5-fluorouracil: a preliminary report. ( Ansfield, F; Cornell, G; Davis, H; Hill, G; Klotz, J; Minton, J; Nealon, T; Ramirez, G; Wilson, W, 1977)
"Fifty consecutive patients with colorectal cancer but no evidence of secondary deposits in the liver were included in an ongoing controlled clinical trial of adjuvant liver perfusion aimed at reducing the incidence of hepatic metastases."2.64Adjuvant liver perfusion in colorectal cancer: initial results of a clinical trial. ( Brooman, P; Rowling, JT; Taylor, I, 1977)
"Twenty patients with advanced colon cancer were treated with a combination of low-dose weekly cyclophosphamide, vincristine, and methotrexate (COM) after demonstrated progression of disease with 5-fluorouracil (5-FU)."2.64Phase II trial of a combination of cyclosphamide, vincristine, and methotrexate in advanced colorectal carcinoma. ( Desai, SA; DeWys, WD; Taylor, SG, 1978)
"Forty-six adult patients with colorectal cancer were treated with cyclophosphamide and CCNU administered orally and 5-fluorouracil (5-FU) administered either orally or by continuous iv infusion (FCC-CIF), depending on the availability of hospital beds."2.64Chemotherapy for colorectal cancer with 5-fluorouracil, cyclophosphamide, and CCNU: comparison of oral and continuous iv administration of 5-fluorouracil. ( Bedikian, AY; Bodey, GP; Burgess, MA; Livingston, R; Staab, R; Valdivieso, M, 1978)
"Fifty-two untreated patients with colorectal cancer were randomized to receive 5-fluorouracil (5-FU) alternating either with methotrexate (MTX) or Baker's Antifol (BAF) with or without the immunostimulant, levamisole (Program I)."2.64Sequential chemoimmunotherapy of colorectal cancer: evaluation of methotrexate, Baker's Antifol and levamisole. ( Bedikian, AY; Bodey, GP; Burgess, MA; Mavligit, GM; Rodriguez, V; Valdivieso, M, 1978)
"route."2.64A double-blind comparison of intensive course 5-flourouracil by oral vs. intravenous route in the treatment of colorectal carcinoma. ( Bruckner, HW; Hahn, RG; Moertel, CG; Schutt, AJ, 1975)
"Omission of radiotherapy in rectal cancer is analyzed in the context of historical findings, as well as more recent data describing risk stratification of stage II-III disease, surgical optimization, imaging limitations, improvement in systemic chemotherapeutic agents, and contemporary studies evaluating selective omission of radiotherapy."2.58The Selective Use of Radiation Therapy in Rectal Cancer Patients. ( Czito, B; Martella, A; Palta, M; Willett, C, 2018)
"Multimodality management of rectal cancer continues to evolve; total mesorectal excision is the cornerstone."2.55Randomized Clinical Trials in Colon and Rectal Cancer. ( George, TJ; Iqbal, A, 2017)
"Rectal squamous cell carcinoma is a rare tumour; it management should be based on anal curative and conservative intent chemoradiation."2.53[Rectal squamous cell carcinoma treatment: Retrospective experience in two French university hospitals, review and proposals]. ( Bosset, JF; Huguet, F; Loganadane, G; Schernberg, A; Servagi-Vernat, S; Touboul, E, 2016)
"Solitary adrenal metastasis of rectal cancer is comparatively rare condition and it is difficult to be diagnosed because it doesn't have any characteristic symptoms."2.52[A CASE OF SOLITARY ADRENAL TUMOR METASTASIZED FROM RECTAL CANCER]. ( Fukuda, H; Iida, S; Iizuka, J; Ikeda, T; Kondo, T; Omae, K; Takagi, T; Tanabe, K; Toda, N, 2015)
"Capecitabine has been widely recognized in the nCRT for patients with LARC, and has the tendency to replace 5-FU."2.50[Advances in new chemotherapeutic drugs for preoperative chemoradiation of locally advanced rectal cancer]. ( Gao, Y; Liu, M; Xiao, L, 2014)
"A 48-year-old man with colorectal cancer and right inguinal lymph node metastasis had previously undergone radiotherapy and chemotherapy (uracil/tegafur/leucovorin) after a colostomy in another hospital before being referred to us."2.50[Disappearance of a gastric lesion following modified FOLFOX6 chemotherapy in a patient with metastatic colorectal cancer: a case report and literature review]. ( Aihara, T; Fukuda, S; Iino, C; Mikami, T; Sakamoto, J; Sawaya, M; Tanaka, M; Tono, H; Yamagata, R; Yoshida, K, 2014)
"Primary squamous cell carcinoma of the rectum is a rare malignancy."2.49Concurrent chemoradiotherapy for squamous cell carcinoma of the rectum. ( Jeong, BG; Kim, DY; Kim, SY, 2013)
" We started combination chemotherapy with 5-fluorouracil, Leucovorin and oxaliplatin(modified FOLFOX6)at a 20% lower than standard dosage for safety."2.49[A case of metastatic colorectal cancer with icterus due to multiple liver metastases treated effectively by FOLFOX plus bevacizumab]. ( Fukuda, K; Koja, S; Terasawa, T; Yasuda, K, 2013)
"The treatment of rectal cancer has evolved significantly in recent decades."2.49[Radiotherapy-associated morbidity and mortality in rectal surgery]. ( Büchler, MW; Kulu, Y; Ulrich, A, 2013)
"Oxaliplatin (OX), in combination with fluoropyrimidine (5-fluorouracil or Capecitabine, FU)-based regimens and radiation, has been expected to both enhance primary tumour shrinkage and reduce micrometastases at distant sites in the neoadjuvant chemoradiotherapy (CRT) for locally advanced rectal cancer (LARC)."2.49Short term results of neoadjuvant chemoradiotherapy with fluoropyrimidine alone or in combination with oxaliplatin in locally advanced rectal cancer: a meta analysis. ( An, X; Cai, PQ; Ding, PR; Fang, YJ; Gao, YH; Goodman, K; Kong, LH; Lin, JZ; Lin, X; Pan, ZZ; Wan, DS; Wang, FH, 2013)
"Overall, 16,215 patients with colorectal cancer were enrolled, 9,785 being affected with rectal carcinoma."2.48Postoperative adjuvant chemotherapy in rectal cancer operated for cure. ( Harling, H; Kirkeby, LT; Mocellin, S; Petersen, SH; Wille-Jørgensen, P, 2012)
"Capecitabine is a rationally designed oral prodrug that is converted into 5-FU by intracellular thymidine phosphorylase."2.48The role of capecitabine in locally advanced rectal cancer treatment: an update. ( Cejas, P; Feliu, J; Fernández-Martos, C; Machancoses, AH; Moreno-García, V; Nogué, M, 2012)
"Here, we report a case with recurrence of rectal cancer who received FOLFIRI with bevacizumab chemotherapy under haemodialysis, and obtained good tumor control."2.48[FOLFIRI with bevacizumab chemotherapy for a patient with recurrence of rectal cancer under haemodialysis for chronic renal failure]. ( Endo, T; Hasegawa, H; Hoshino, G; Hoshino, H; Hoshino, Y; Ishii, Y; Kitagawa, Y; Matsunaga, A; Ochiai, H; Seo, Y; Shigeta, K, 2012)
" Given the oral bioavailability of capecitabine as well as in-vitro and in-vivo findings showing higher expression of thymidine phosphorylase in tumor cells and xenografts compared with normal tissue, capecitabine is an evolving candidate in the management of colorectal cancer with antimetabolite-based therapy."2.47Evolution of 5-fluorouracil-based chemoradiation in the management of rectal cancer. ( Patel, PA, 2011)
"He was diagnosed with interstitial pneumonitis."2.47[A case of interstitial lung diseases in patient treated with oxaliplatin, 5-fluorouracil and leucovorin (FOLFOX)]. ( Fukushima, M; Hamada, A; Ishizaka, T; Mukai, J; Nakagawa, M; Sawada, R; Takahashi, N; Yoshihara, Y, 2011)
"The management of rectal cancer has undergone significant evolution with advances in surgery, radiation therapy, and chemotherapy."2.47Beyond 5-fluorouracil: the emerging role of newer chemotherapeutics and targeted agents with radiation therapy. ( Czito, BG; Willett, CG, 2011)
"5-Fluorouracil (5-FU) is a commonly used anti-neoplastic agent."2.47Symptomatic 5-fluorouracil-induced sinus bradycardia. ( Lee, AD; McKay, MJ, 2011)
"Keywords for the search were: "rectal cancer", "preoperative radiotherapy", "phase II-III", "preoperative chemotherapy", "adjuvant chemotherapy" and "surgery"."2.47[Preoperative radiochemotherapy for rectal cancer: forecasting the next steps through ongoing and forthcoming studies]. ( Bosset, JF; Créhange, G; Maingon, P, 2011)
" The question to be addressed is how and when to apply intensified systemic therapy with adequate dosage and intensity as well as acceptable treatment-associated toxicity."2.47[Rectal cancer: current status of multimodal therapy--when and how?]. ( Becker, H; Gaedcke, J; Ghadimi, BM; Hess, C; Liersch, T; Rödel, C, 2011)
"A total number of 53 metastatic colorectal cancer patients were treated with BEV-CAPIRI regimen."2.46Efficacy and safety of bevacizumab plus capecitabine and irinotecan regimen for metastatic colorectal cancer. ( Bozkurt, MT; Cirak, Y; Degirmenci, M; Demir Piskin, G; Durusoy, R; Gorumlu, G; Karabulut, B; Karaca, B; Sanli, UA; Tunali, D; Uslu, R, 2010)
"In colorectal cancer, increased response rates are achieved by cetuximab and panitumumab within standard chemotherapy schedules, but not in chemoradiation regimens."2.46Cetuximab and chemoradiation for rectal cancer--is the water getting muddy? ( Glynne-Jones, R; Harrison, M; Mawdsley, S, 2010)
"Capecitabine has been developed as a prodrug of FU, with the goal of improving tolerability and intratumor drug concentration through tumor-specific conversion to the active drug."2.45The role of capecitabine in the management of tumors of the digestive system. ( Gennatas, C; Gennatas, S; Michalaki, V, 2009)
"The successful management of rectal cancer requires a multidisciplinary approach, with treatment decisions based on precise patient evaluations by a group of clinicians, including surgeons, gastroenterologists, medical and radiation oncologists, radiologists, and pathologists."2.45The multidisciplinary management of rectal cancer. ( Hoffe, SE; Meredith, KL; Shibata, D, 2009)
"The basic principle in the treatment of rectal cancer is the complete surgical removal of the tumor together with the lymphatic drainage region, i."2.45Limitation of surgical radicality in rectal cancer responding to neoadjuvant therapy. ( Hempen, HG; Raab, HR; Troja, A, 2009)
"Standard therapy for locally advanced rectal cancer (LARC) is concurrent neo-adjuvant chemo-radiation using infusional 5-fluorouracil (CIV-5-FU)."2.44Capecitabine vs continuous infusion 5-FU in neoadjuvant treatment of rectal cancer. A retrospective review. ( Almhanna, K; Hashmi, S; Kim, R; Saif, MW; Zelterman, D, 2008)
"Treatment of rectal cancer over the last two decades has evolved with changes in techniques of surgery and radiation based on national and international trials."2.44Total mesorectal excision and management of rectal cancer. ( Phang, PT; Pinsk, I, 2007)
"The management of rectal cancer has undergone significant evolution with advances in surgery, radiation therapy, and chemotherapy."2.44Combined-modality therapy for rectal cancer: future prospects. ( Bendell, JC; Czito, BG; Willett, CG, 2007)
"Capecitabine is an oral fluoropyrimidine that generates 5-FU preferentially within the tumor."2.44Capecitabine and radiotherapy as neoadjuvant treatment for rectal cancer. ( Ben-Josef, E, 2007)
"Patients diagnosed with rectal cancer should undergo locoregional staging with transrectal endoscopic ultrasound (EUS) or surface coil array MRI of the pelvis if that technique is available."2.44Current options for the management of rectal cancer. ( O'Neil, BH; Tepper, JE, 2007)
"Capecitabine is an oral prodrug of 5-FU that has potential advantages compared with intravenous 5-FU, including ease of administration and potentially increased therapeutic effect."2.44The use of capecitabine in the combined-modality therapy for rectal cancer. ( Liauw, SL; Minsky, BD, 2008)
"Adjuvant chemotherapy for colon cancer and combined chemotherapy and radiation therapy (RT) for rectal cancer increases the proportion of patients cured of their disease."2.43An overview of approaches to adjuvant therapy for colorectal cancer in the United States. ( Hobday, TJ, 2005)
"We relate 2 cases reports about rectal cancer and pregnancy."2.43[Management of rectal cancer in pregnant women]. ( Benouna, J; Classe, JM; Dravet, F; Dupré, PF; Mahé, MA; Pigeau, H; Pioud, R, 2005)
"Formerly the treatment of gastrointestinal cancers was exclusively surgical."2.43[Progress in the treatment of gastrointestinal cancers due to introduction of neoadjuvant concept]. ( Cseke, L; Esik, O; Horváth Ors, P; Kalmár, K; Papp, A; Yousuf, AF, 2006)
"The rare finding of heterotopic ossification in a case of primary rectal adenocarcinoma is described along with a review of the literature."2.42Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism. ( Gottfried, MR; Jones, R; Kypson, AP; Morphew, E; Seigler, HF, 2003)
"The standard in rectal cancer has been to add adjuvant radiation therapy to surgery in patients with stage II and III disease."2.42Adjuvant radiation therapy of patients with rectal cancer. ( Bechtel, J; Tepper, J, 2003)
"Adjuvant therapy of rectal cancer follow the progress obtained in colon cancer using adjuvant fluorouracil based chemotherapy and is also based on radiotherapy."2.42[Adjuvant therapy of rectal cancer]. ( Bouaouina, N; Boussen, H, 2003)
"Adjuvant therapy of colorectal cancer with oral fluorinated pyrimidines is attractive because of its ease of administration and good tolerability."2.42Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials. ( Burzykowski, T; Buyse, M; Hamada, C; Ohashi, Y; Piedbois, P; Sakamoto, J, 2004)
"Adjuvant therapy for colorectal cancer has been one of the most important contributions of medical oncology to the health of the population, saving more lives annually than more effective therapy for less common cancers, such as Hodgkin's disease."2.42Adjuvant therapy for rectal cancer in the elderly. ( Cohen, SM; Neugut, AI, 2004)
"Adjuvant radiation therapy for rectal cancer is not widely used in Japan, while chemotherapy is considered the adjuvant treatment of choice."2.41[Progress in adjuvant therapy for colorectal cancer]. ( Kakeji, Y; Kohnoe, S; Maehara, Y, 2002)
"Capecitabine is a novel fluoropyrimidine carbamate, orally administered and rationally designed to undergo tumor-selective activation."2.41[Capecitabine--a review of its antitumor activity and toxicity in clinical studies]. ( Maeda, Y; Sasaki, T, 2000)
"Advanced colorectal cancer has traditionally been treated with 5-fluorouracil, alone or in combination with leucovorin."2.41[New drugs in the treatment of advanced colorectal cancer]. ( Harboe, K; Lind, A; Ogreid, D; Todnem, K; Zotova, L, 2000)
"Capecitabine has the potential to replace bolus or continuous infusion 5-FU as the standard treatment for rectal cancer and offers a potentially enhanced therapeutic ratio."2.41Improving chemoradiotherapy in rectal cancer. ( Debus, J; Glynne-Jones, R, 2001)
"In patients with Dukes' B or C rectal cancer, combined radiation and FU increase survival and decrease local and distal recurrence."2.40Adjuvant therapy of colorectal cancer. ( Cohen, A; Kemeny, N; Saltz, L, 1997)
"In patients with resectable rectal cancer, randomized trials reveal an improvement in local control and survival with postoperative combined modality therapy."2.40The role of radiation therapy in rectal cancer. ( Minsky, BD, 1997)
"The management of distal rectal cancer is in evolution."2.40Sphincter preservation in rectal cancer. Local excision followed by postoperative radiation therapy. ( Willett, CG, 1998)
" Raltitrexed, a thymidylate synthase inhibitor, offers similar antitumoral activity together with a tolerability in comparison to standard 5-fluorouracil based chemotherapy and its simple dosage schedule also contributes to better quality of life."2.40[Drug clinics. How I treat. II. Therapeutic approaches to metastatic colorectal cancer]. ( Bours, V; Fillet, G; Jerusalem, G, 1998)
"The majority of these cases were anal cancers with proximal extension into the rectum and were excluded."2.40Squamous-cell carcinoma of the colon responsive to combination chemotherapy: report of two cases and review of the literature. ( Francis, B; Juturi, JV; Koontz, PW; Wilkes, JD, 1999)
"Despite of improvement of results in rectum cancer treatment after systematical introduction of total mesorectal excision as a standard procedure to control the compartment disease, surgical radicality may be limited in cases with large tumours in ventral position because of eccentric location of the rectum in the perirectal fat."2.40[Rectal carcinoma. Optimizing treatment by neoadjuvant and adjuvant therapy?]. ( Fasolini, F, 1999)
"Sixty-six patients with colorectal cancer were studied regarding effects of prevention of hepatic recurrence in completely performed portal infusion chemotherapy."2.40[Is portal infusion chemotherapy uneffective for hepatic recurrence after resection for colorectal cancer?]. ( Akaishi, O; Tsukikawa, S; Yabe, K; Yamaguchi, S; Yamamura, T, 1999)
"We report herein a case of rectal carcinoid with multiple liver metastasis successfully treated with hepatic arterial infusion of methotrexate (MTX) and 5-fluorouracil (5-FU)."2.40[A case of liver metastases of rectal carcinoid successfully treated with hepatic arterial infusion of methotrexate and 5-fluorouracil]. ( Idezuki, Y; Ishida, H; Nakada, H; Suzuki, T; Tada, M; Takeuchi, I, 1999)
"Despite simple screening procedures rectal cancer is often advanced when discovered."2.40Combined modality therapy of rectal cancers. ( Juretic, A; Samija, M; Sobat, H, 1999)
"In the treatment of stages 2 and 3 rectal cancer, significant reductions in local recurrence and death rates have been achieved with the combination of 5-fluorouracil and radiation therapy."2.39Role of adjuvant therapy in surgically resected colorectal carcinoma. ( Sinicrope, FA; Sugarman, SM, 1995)
"We present an additional case of rectal squamous cell carcinoma (SCC) complicating chronic ulcerative colitis in a 33-year-old woman who had the disease for 15 years."2.39Squamous cell carcinoma complicating idiopathic inflammatory bowel disease. ( Butler, B; Doerr, R; Kulaylat, MN; Satchidanand, SK; Singh, A, 1995)
" Preoperative radiotherapy with a dosage of 35-45 Gy can lead to downstaging of rectal cancer."2.39[Developments up to now and current status of adjuvant chemo- and radiotherapy in colonic and rectal carcinoma]. ( Eble, MJ; Kraus, TW; Raeth, U, 1994)
"For Dukes' C colon cancer, postoperative adjuvant chemotherapy with a combination of fluorouracil and levamisole is now recommended as standard therapy."2.39Adjuvant postoperative therapy of gastrointestinal malignancies. ( Ilson, DH; Kelsen, DP, 1994)
"Work has been done in gastric cancer, pancreatic cancer, and colon and rectal cancer, all of which demonstrate an advantage in certain clinical situations for combined-modality therapy."2.38Combined radiotherapy and chemotherapy in the treatment of gastrointestinal malignancies. ( Tepper, JE, 1992)
"Some aspects of colorectal cancer remain controversial, particularly screening recommendations and monitoring of carcinoembryonic antigen levels."2.38Colorectal cancer. Recent developments and continuing controversies. ( Lee, MW, 1992)
"Several trials in rectal cancer show an advantage for 5-FU combined with semustine and radiation therapy in terms of disease-free survival, overall survival, or both; the contribution of semustine has been questioned and is currently being investigated."2.38Current treatment approaches in colorectal cancer. ( Grem, JL, 1991)
"Conservative procedures to treat rectal cancer are also gaining support because of reduced morbidity and mortality, avoidance of colostomy, and excellent survival figures in selected patients."2.38Surgical therapy of early rectal carcinoma. ( Curley, SA; Rich, TA; Roh, MS, 1989)
" To date, a lot of phase II studies have been conducted, but there are many distance in each clinical data concerning response rate and side effect by the difference between their clinical methods with respect to the interval between methotrexate and 5-fluorouracil, or the dosage of each drugs."2.37[Current studies of sequential methotrexate and 5-fluorouracil treatment in cancer chemotherapy]. ( Murakami, M; Ota, K, 1988)
"Fluorouracil has been the mainstay of chemotherapy in colorectal cancer for many years."2.37Biochemical modulation of fluorouracil therapy in advanced colorectal cancer. ( Mackintosh, J; Tattersall, MH, 1987)
"Certainly in treatment of the carcinoid tumor surgery has a well-established curative and palliative potential."2.36Treatment of the carcinoid tumor and the malignant carcinoid syndrome. ( Moertel, CG, 1983)
"The clinical diagnosis was squamous cell carcinoma of the lower rectum, cT4b(bladder and seminal vesicle)N0M0, cStage Ⅱc."1.91[A Case of Squamous Cell Carcinoma of the Lower Rectum]. ( Doki, Y; Eguchi, H; Hata, T; Miyoshi, N; Ogino, T; Osaki, M; Sakai, D; Satoh, T; Sekido, Y; Takahashi, H; Uemura, M, 2023)
"To evaluate the association of age with treatment-related adverse events and survival in patients with mCRC and explore the potential underlying factors."1.91Association of Age With Treatment-Related Adverse Events and Survival in Patients With Metastatic Colorectal Cancer. ( Delgado, MG; Gomez, MF; Hubbard, JM; Ji, R; Kim, RD; Knepper, TC; Laber, DA; Meng, L; Permuth, JB; Thapa, R; Wang, X; Xie, H, 2023)
"BRAF V600E mutant-metastatic colorectal cancer (mCRC) is characterized by its short survival time."1.91Treatment of metastatic colorectal cancer with BRAF V600E mutation: A multicenter real-world study in China. ( Chang, W; Fu, J; Lin, Q; Lv, Y; Tang, W; Wang, G; Xu, J; Xu, Y; Zhang, T; Zheng, X; Zhu, Z, 2023)
" We investigated whether plasma angiogenesis factors could predict the efficacy of biologics combined with chemotherapy in first-line (1L) treatment in patients with RAS wild-type mCRC and the dynamics of plasma angiogenesis factors at progression during 1L treatment."1.91Role of plasma angiogenesis factors in the efficacy of first-line chemotherapy combined with biologics in RAS wild-type metastatic colorectal cancer: Results from the GI-SCREEN CRC-Ukit study. ( Abe, Y; Asano, C; Bando, H; Denda, T; Esaki, T; Kagawa, Y; Kato, T; Kawakami, H; Matsuhashi, N; Nishina, T; Nomura, S; Satake, H; Shiozawa, M; Sunakawa, Y; Takahashi, N; Takashima, A; Taniguchi, H; Yamazaki, K; Yasui, H; Yoshino, T; Yuki, S, 2023)
" Number of cycles, dose delays for any cause, and dose reductions for adverse events (AEs) were comparable between age classes."1.91Quality of life, effectiveness, and safety of aflibercept plus FOLFIRI in older patients with metastatic colorectal cancer: An analysis of the prospective QoLiTrap study. ( Anchisi, S; Bohanes, P; Derigs, HG; Geffriaud-Ricouard, C; Grünberger, B; Gueldner, M; Hofheinz, RD; Piringer, G; Scholten, F; Schwarz, L; Thaler, J; von Moos, R, 2023)
"To assess the toxicity patterns and effectiveness of doublet chemotherapy when administered at reduced doses of 20% (FOLFOX or FOLFIRI) in combination with anti-EGFR antibodies (cetuximab or panitumumab) in old, vulnerable patients with metastatic colorectal cancer (mCRC)."1.72Reduced-dose of doublet chemotherapy combined with anti-EGFR antibodies in vulnerable older patients with metastatic colorectal cancer: Data from the REVOLT study. ( Aprile, G; Avallone, A; Bilancia, D; Brugnatelli, S; Carlomagno, C; Cicero, G; Cinausero, M; Colombo, A; Corsi, D; Dell'Aquila, E; Pinto, C; Rapisardi, S; Reggiardo, G; Rosati, G, 2022)
"The time elapsed between rectal cancer diagnosis and NCRT initiation is significantly associated with pCR."1.72Rapid Initiation of Neoadjuvant Chemoradiotherapy After Diagnosis is Associated With Improved Pathologic Response in Locally Advanced Rectal Cancer. ( Bar-Sela, G; Lutsyk, M; Turgeman, I, 2022)
" The efficacy and adverse effects of maintenance treatment were compared between the two groups."1.72Efficacy and safety analysis of bevacizumab combined with capecitabine in the maintenance treatment of RAS-mutant metastatic colorectal cancer. ( Cha, Y; Huang, W; Tian, Y; Xiong, H; Yuan, X; Zhang, H, 2022)
"We diagnosed as having rectal cancer with multiple lung metastases."1.72[A Case of Rectal Cancer and Multiple Lung Metastases That Had Complete Response Treated by XELOX plus Bevacizumab after Primary Lesion Resection]. ( Aomatsu, K; Hiramatsu, S; On, O; Sugimoto, A, 2022)
" The most frequent grade 3/4 adverse events were: asthenia (21."1.72Efficacy and safety of FOLFIRI/aflibercept (FA) in an elderly population with metastatic colorectal cancer (mCRC) after failure of an oxaliplatin-based regimen. ( Alonso de Castro, B; Cameselle García, S; Carmona Campos, M; Cousillas Castiñeiras, A; De la Cámara Gómez, JC; Fernández-Montes, A; Gómez-Randulfe Rodríguez, MI; González Villarroel, P; Martínez-Lago, N; Méndez Méndez, JC; Romero Reinoso, C; Salgado Fernández, M; Vidal Insua, Y, 2022)
"Colorectal cancer is one of the most commonly diagnosed malignancies globally and nearly half of these patients develop metastatic colorectal cancer (mCRC)."1.72Tumor calcification is associated with better survival in metastatic colorectal cancer patients treated with bevacizumab plus chemotherapy. ( Liu, JY; Liu, X; Long, YX; Qiu, M; Zhou, YW, 2022)
"Obstructive colorectal cancer is locally advanced colorectal cancer with a poor prognosis."1.72A Prospective, Single-arm, Multicenter Trial of Diverting Stoma Followed by Neoadjuvant Chemotherapy Using mFOLFOX6 for Obstructive Colon Cancer: YCOG 1305 (PROBE Study). ( Endo, I; Ishibe, A; Misumi, T; Nakagawa, K; Ota, M; Suwa, H; Suwa, Y; Watanabe, J, 2022)
"Following the diagnosis of RS rectal cancer with muc, pT4a, N3(14/15), M1c, P1, pStage Ⅳc, RAS/BRAF: wild type, treatment was initiated with mFOLFOX6 plus panitumumab(Pmab)."1.62[A Case of Hyperammonemic Encephalopathy following mFOLFOX6 plus Panitumumab Therapy for Rectal Cancer]. ( Eguchi, S; Fukuoka, T; Iseki, Y; Lee, S; Miki, Y; Muguruma, K; Nagahara, H; Ohira, M; Shibutani, M; Tamura, T; Tanaka, H; Toyokawa, T; Tsujio, G; Yashiro, M; Yoshii, M, 2021)
"More capecitabine-treated patients received post-operative oxaliplatin (44."1.62Real-world outcomes for neoadjuvant capecitabine versus infusional 5-fluorouracil in the treatment of locally advanced rectal cancer. ( Christie, M; Croxford, M; Faragher, I; Gibbs, P; Guerrieri, M; Jones, IT; Kosmider, S; Lee, M; Loft, M; Steel, M; Tie, J; Wong, HL; Wong, R, 2021)
"We present a case of locally advanced rectal cancer(LARC)treated by robot assisted intersphincteric resection(ISR)and lateral lymph node dissection(LLND)after neoadjuvant chemotherapy(NAC)."1.62[A Case of Locally Advanced Rectal Cancer Treated by Robot Assisted Intersphincteric Resection after Neoadjuvant Chemotherapy]. ( Hata, T; Imada, A; Kagawa, Y; Katsura, Y; Kawai, K; Kusafuka, H; Masuzawa, T; Murakami, K; Murata, K; Omura, Y; Sakamoto, T; Takeda, Y; Takeno, A, 2021)
"The overall mEHT group had a comparable response and survival using less radiation dosing compared with standard care; the subgroup with large tumors showed improved efficacy for tumor regression after mEHT."1.62Beneficial effects of modulated electro-hyperthermia during neoadjuvant treatment for locally advanced rectal cancer. ( Cha, J; Kim, S; Lee, JH; You, SH, 2021)
" The incidences of chemotherapy-related adverse reactions, postoperative complications, and clinical pathological reactions were analyzed."1.62Safety and efficacy of preoperative mFOLFOX6 regimen chemotherapy for locally resectable advanced rectal cancer. ( Jiang, Z; Liu, L, 2021)
"Our study revealed that there was no adverse pathologic or oncological outcome with the concurrent use of PPIs along with Cape-NACRT in the treatment of LARC."1.62Concomitant Use of Proton Pump Inhibitors With Capecitabine Based Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer: Is it Safe? ( Abraham, AG; Ghosh, S; Joseph, K; Mahfouz, M; Menon, A; Mulder, K; Nijjar, T; Paulson, K; Roa, W; Severin, D; Tankel, K; Thachuthara, JJ; Usmani, N; Warkentin, H, 2021)
"Progress in rectal cancer therapy has been hindered by the lack of effective disease-specific preclinical models that account for the unique molecular profile and biology of rectal cancer."1.56Modeling rectal cancer to advance neoadjuvant precision therapy. ( Becker, SA; Camp, ER; Cross, A; Curl, E; Findlay, VJ; Hill, EG; Hoffman, BJ; Janakiraman, H; Lewin, D; Timmers, C; Wang, C; Warren, GW; Zhu, Y, 2020)
"Endpoints were pathologic response, resection margin and overall survival (OS), disease free survival (DFS), local recurrence free survival (LRFS), and metastasis free survival (MFS)."1.56Improved Outcomes for Responders After Treatment with Induction Chemotherapy and Chemo(re)irradiation for Locally Recurrent Rectal Cancer. ( Bloemen, JG; Burger, JWA; Creemers, GJM; Kusters, M; Nederend, J; Nieuwenhuijzen, GAP; Peulen, HMU; Roef, MJ; Rutten, HJT; van Lijnschoten, G; van Zoggel, DMGI; Voogt, ELK, 2020)
"Metformin is an attractive alternative radiosensitizing agent to be considered in future studies/trials."1.56Metformin as an Alternative Radiosensitizing Agent to 5-Fluorouracil During Neoadjuvant Treatment for Rectal Cancer. ( Asprino, PF; Camargo, AA; Costa, ÉT; Fernandes, JM; Jandrey, EHF; Koyama, FC; Leite, KRM; Perez, RO, 2020)
"A 68-year-old female with rectal cancer underwent low anterior resection with regional lymph node dissection."1.56[Long-Term Survival of a Patient with Advanced Recurrent Rectal Cancer Treated with a Multidisciplinary Therapy including Five Operations-A Case Report]. ( Adikrisna, R; Gokita, K; Nara, A; Onishi, I; Sueyoshi, K; Udagawa, M; Watanabe, Y, 2020)
"A 65-year-old male was diagnosed with rectal cancer invading the urinary bladder, swollen para-aorticlymph nodes, and multiple liver metastases in abdominal CT."1.56[Bladder-Sparing Surgery with Preoperative Chemotherapy for Rectal Cancer with Urinary Bladder Involvement-A Case Report]. ( Ishida, T; Kajiwara, T; Kamei, T; Karasawa, H; Kohyama, A; Kokubo, S; Naitoh, T; Ohnuma, S; Suzuki, H; Unno, M; Watanabe, K, 2020)
"Pathological diagnosis was carcinoid, se, ly2, v0, n1."1.56[A Case of Malignant Lymphoma Undergoing HAI Treatment for Multiple Liver Metastases of Carcinoid That Appeared about Nine Years after Resection of Rectal Carcinoid with Liver Metastases]. ( Gofuku, J; Hasuike, Y; Higuchi, I; Ishikawa, A; Miyamoto, M; Mori, Y; Tokunaga, M; Tsuchida, Y; Urano, N, 2020)
"Treatment options for locally advanced rectal cancer have continued to consist largely of chemotherapy, chemoradiation, and/or surgical resection."1.56Neoadjuvant Immunotherapy-Based Systemic Treatment in MMR-Deficient or MSI-High Rectal Cancer: Case Series. ( Cho, M; Damle, N; Dayyani, F; Demisse, R; Eng, C; Fakih, M; Gholami, S; Gong, J; Halabi, W; Ji, J; Kim, E; Liu, J; Louie, R; McKenny, M; Monjazeb, A; Oesterich, L; Tam, K, 2020)
"The patient had locally advanced rectal cancer with widespread contact with the sacrum, and preoperative radiochemotherapy (S-1 100 mg/day plus radiotherapy 50 Gy/25 Fr)was performed."1.56[A Case of Advanced Rectal Cancer Successfully Treated with Preoperative Radiochemotherapy]. ( Ichikawa, J; Koreeda, N; Nishiki, M; Noritomi, T; Okamoto, T; Ryu, S; Sannomiya, H; Sato, K; Shin, Y; Yamana, I; Yanagisawa, J; Yoshida, Y, 2020)
"Sixty-two patients with metastatic colorectal cancer received aflibercept (4 mg/kg) plus FOLFIRI every 2 weeks."1.51Exploration of potential prognostic biomarkers in aflibercept plus FOLFIRI in Japanese patients with metastatic colorectal cancer. ( Chiron, M; Denda, T; Esaki, T; Fujii, H; Hamaguchi, T; Itabashi, M; Kajiwara, T; Komatsu, Y; Kudo, T; Moriwaki, T; Nagashima, F; Nakajima, TE; Oki, E; Otsu, S; Sasaki, T; Sato, T; Sugimoto, N; Takahashi, S; Ura, T; Yamazaki, K; Yoshino, T, 2019)
"In 31 cases of rectal cancer, H19 and UCA1 expression levels in biopsy and resected tissue were comparable."1.51In vitro and in vivo studies on the association of long non‑coding RNAs H19 and urothelial cancer associated 1 with the susceptibility to 5‑fluorouracil in rectal cancer. ( Ishino, K; Koizumi, M; Kudo, M; Naito, Z; Sakatani, T; Wada, R; Yamada, T; Yokoyama, Y; Yoshida, H, 2019)
"Vulvar metastasis of colorectal cancer (CRC) and acquired resistance to cetuximab is a very rare phenomenon."1.51Emergence of KRAS p.G13D mutation and acquired resistance to cetuximab in colorectal cancer with vulvar metastasis: A case report. ( Ni, X; Qiang, W; Wu, Q; Zhang, C; Zhao, J, 2019)
"We report 2 cases of advanced colorectal cancer achieving complete response by FOLFOXIRI plus bevacizumab."1.51[Two Cases of Advanced Colorectal Cancer Achieving Complete Response by FOLFOXIRI plus Bevacizumab-A Case Report]. ( Aizawa, M; Endo, S; Isohata, N; Nemoto, D; Nemoto, T; Oshibe, I; Saito, T; Soeta, N; Takayanagi, D; Togashi, K; Utano, K, 2019)
"We report a case oflocally advanced rectal cancer with maintained long-term cCR after chemotherapy alone."1.51[A Case of Long-Term Clinical Complete Response after Chemotherapy for Locally Advanced Rectal Cancer]. ( Abe, T; Hayashi, K; Itoh, S; Kikuchi, I; Kimura, T; Kurihara, Y; Ota, S; Sato, T; Shimbo, T; Wakabayashi, T, 2019)
"A total of 118 rectal cancer patients receiving preoperative CRT were enrolled."1.51Identification of Predictors of Recurrence in Patients with Lower Rectal Cancer Undergoing Neoadjuvant Chemotherapy: A Direct Comparison of Short-Course and Long-Course Chemoradiotherapy. ( Araki, T; Fujikawa, H; Hiro, J; Ide, S; Kusunoki, M; Ohi, M; Okugawa, Y; Saigusa, S; Toiyama, Y; Yamamoto, A; Yasuda, H; Yoshiyama, S, 2019)
"The rates of locoregional recurrence (2."1.51Adjuvant Chemotherapy in Rectal Cancer Patients Treated With Preoperative Chemoradiation and Total Mesorectal Excision: A Multicenter and Retrospective Propensity-Score Matching Study. ( Chung, MJ; Jang, HS; Jeong, JU; Jeong, S; Kim, SH; Lee, JH; Nam, TK; Song, JH; Yu, M, 2019)
"Preoperative radio(chemo)therapy in rectal cancer may irreversibly damage pelvic bone marrow (PBM) and impair the tolerance of subsequent chemotherapy."1.51Impact of pelvic bone marrow irradiation on the hematological toxicity of subsequent chemotherapy in rectal cancer. ( Michalski, W; Spalek, M; Wyrwicz, L, 2019)
"A 35-year-old woman was diagnosed with rectal cancer with metastasis to the liver."1.51Rechallenge capecitabine after fluoropyrimidine-induced cardiotoxicity in rectal cancer: A case report. ( Ouyang, Y; Peng, T; Tong, K, 2019)
"Pathologists assess rectal cancers that have responded significantly to neoadjuvant therapy more thoroughly."1.51Variation in the Thoroughness of Pathologic Assessment and Response Rates of Locally Advanced Rectal Cancers After Chemoradiation. ( Avila, K; Chow, OS; Chu, P; Garcia-Aguilar, J; Keskin, M; Patil, S; Shia, J; Smith, DD; Smith, JJ; Widmar, M, 2019)
"Examinations revealed advanced rectal cancer involving the anal canal with invasion of the left-sided levator ani muscle."1.51[Curative Transanal Resection after Neoadjuvant Chemotherapy for Lower Rectal Cancer-A Case Report]. ( Aizawa, M; Endo, K; Endo, S; Isohata, N; Nemoto, D; Nemoto, T; Oshibe, I; Saito, T; Soeta, N; Takayanagi, D; Togashi, K; Utano, K, 2019)
"We reported 2 cases of colorectal cancer receiving neoadjuvant chemotherapy(NAC)with the aim of curative resection or anal preservation."1.51[Two Cases of Locally Advanced Rectal Cancer and Lower Rectal Cancer Resected Successfully That Enabled Anus Preservation after Preoperative Chemotherapy]. ( Chiku, T; Hashiba, T; Sano, W; Shinoda, K; Togawa, Y; Yamashita, K, 2019)
"Distant metastasis still remained a major concern in pCR patients following nCRT and TME."1.51Pathological complete response may underestimate distant metastasis in locally advanced rectal cancer following neoadjuvant chemoradiotherapy and radical surgery: Incidence, metastatic pattern, and risk factors. ( Chi, P; Huang, Y; Lin, H; Lu, X; Sun, Y; Wu, X; Zhang, Y, 2019)
"We report a case of locally advanced rectal cancer presenting with perforation that was successfully resected after preoperative chemotherapy."1.51[Locally Advanced Rectal Cancer Presenting with Perforation That Was Successfully Resected after Preoperative Chemotherapy with mFOLFOX6 plus Panitumumab]. ( Hotei, H; Kuwada, A; Maeda, Y; Murao, N; Sakabe, R; Sakoda, T; Tahara, K; Yoshimura, K, 2019)
"Patients with rectal cancer who achieve complete clinical response after neoadjuvant chemoradiation have been managed by organ-preserving strategies and acceptable long-term outcomes."1.51Achieving a Complete Clinical Response After Neoadjuvant Chemoradiation That Does Not Require Surgical Resection: It May Take Longer Than You Think! ( Andrade, A; Araújo, SEA; Fernandez, LM; Gama-Rodrigues, J; Habr-Gama, A; Perez, RO; São Julião, GP; Vailati, BB, 2019)
"Recurrence and chemoresistance in colorectal cancer remain important issues for patients treated with conventional therapeutics."1.51Effects of metformin and phenformin on apoptosis and epithelial-mesenchymal transition in chemoresistant rectal cancer. ( Jang, H; Kim, A; Kim, H; Kim, MJ; Kim, YH; Lee, SB; Lee, SJ; Myung, JK; Park, EH; Park, JH; Park, S; Shim, S, 2019)
"Capecitabine (Xeloda) is an oral 5-FU prodrug of comparable pharmacodynamic activity, currently preferred in place of 5-FU infusion, its established counterpart in neoadjuvant CRT for rectal cancer."1.48Comparing pathological complete response rate using oral capecitabine versus infusional 5-fluorouracil with preoperative radiotherapy in rectal cancer treatment. ( Evans, T; Jootun, N; Mak, J; Makin, G; Platell, C, 2018)
"For advanced rectal cancer with involved or threatened mesorectal fascia (MRF), current standard is pre-operative long course chemoradiotherapy (PLCRT) with either capecitabine or 5-fluorouracil (5-FU)."1.48Outcome of neoadjuvant chemoradiation in MRI staged locally advanced rectal cancer: Retrospective analysis of 123 Chinese patients. ( Chiang, CL; Lee, FAS; Lee, SF; Poon, CM; Tung, SY; Wong, FCS; Wong, YW, 2018)
" Dosing and completion of prescribed chemotherapy were assessed on the subset of patients who received all therapy at MSK."1.48Adoption of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer. ( Cercek, A; Crane, CH; Garcia-Aguilar, J; Gollub, MJ; Gonen, M; Guillem, JG; Nash, GM; Paty, PB; Reidy, DL; Roxburgh, CSD; Saltz, LB; Segal, NH; Seier, K; Shia, J; Smith, JJ; Stadler, ZK; Strombom, P; Temple, LKF; Vakiani, E; Varghese, A; Weiser, MR; Wu, AJ; Yaeger, R, 2018)
"The NCCN Guidelines for Rectal Cancer are now more closely aligned with those for colon cancer."1.48Management of Locoregional Rectal Cancer. ( Willett, CG, 2018)
"Data on patients with cT3/4 and N+ rectal cancer who were treated in our institution from April 2010 to February 2016 were reviewed retrospectively."1.48Therapeutic effects of oxaliplatin-based neoadjuvant chemotherapy and chemoradiotherapy in patients with locally advanced rectal cancer: a single-center, retrospective cohort study. ( Noie, T; Okuyama, T; Ono, Y; Oya, M; Sameshima, S; Tagaya, N; Takeshita, E; Yamagata, Y; Yoshioka, R, 2018)
"A diagnosis of local recurrence of rectal cancer, peritoneal metastasis and metastatic liver cancer was confirmed."1.48[A Case Describing Treatment with FOLFIRI plus Bevacizumab after a Self-Expandable Metallic Stent Placement for Local Recurrence]. ( Kodama, M; Kondo, S; Miyahara, Y; Yamazaki, K; Yokoyama, M; Yoshida, A, 2018)
"A 56-year-old woman was diagnosed with rectal cancer and liver metastases(Stage IV), and underwent low anterior resection and laparoscopic partial hepatectomy."1.48[Primary Small Bowel Tumor with Simultaneous Lung Metastases from Rectal Cancer - A Case Report]. ( Hayashi, H; Hyodo, M; Inoue, Y; Lefor, AK; Okada, M; Ota, G; Sato, H; Shinohara, S; Tsukahara, M; Yasuda, Y, 2018)
"In order to reduce the frequency and the severity of oxaliplatin-related sensory-neuropathy and preserve antitumor efficacy, we performed alternating 4 mFOLFOX6 and 4 FOLFIRI cycles, in combination with bevacizumab, in patients with metastatic colorectal cancer."1.48[A Case of a Patient with Rectum Cancer with Multiple Metastases, Who Was Able to Undergo Conversion Therapy Using Alternating mFOLFOX6 and FOLFIRI Regimens in Combination with Alternating Cetuximab and Bevacizumab]. ( O'hara, H; Yamamoto, H, 2018)
"Patients with locally advanced rectal cancer (LARC) achieving a pathological complete response (pCR) to neoadjuvant treatment usually have a good prognosis, but only accounted for less than 20%."1.48Complete pathological response following neoadjuvant FOLFOX chemotherapy in BRCA2-mutant locally advanced rectal cancer: a case report. ( Jin, M; Lin, Z; Liu, H; Liu, J; Peng, L; Wang, J; Xue, J; Zhang, D; Zhang, T, 2018)
"Primary cutaneous mucormycosis is an opportunistic fungal infection caused by the order Mucorales, most frequently by the Rhizopus species."1.48Rapidly progressing ulcer and a urine drainage bag. ( Fernandez-Guarino, M; Jimenez-Cauhe, J; Molins-Ruiz, M, 2018)
"Patients with rectal cancer treated with chemoradiotherapy and radical surgery from 2003 to 2015 (N = 222) were included."1.46Oncological Outcomes of Lateral Pelvic Lymph Node Metastasis in Rectal Cancer Treated With Preoperative Chemoradiotherapy. ( Hata, K; Ishihara, S; Kawai, K; Kiyomatsu, T; Morikawa, T; Nozawa, H; Tanaka, T; Watanabe, T, 2017)
"We report a case of locally advanced rectal cancer, treated effectively with chemotherapy consisting of mFOLFOX6 combined with radiotherapy."1.46[A Case of Effective Chemoradiotherapy Using mFOLFOX6 for Locally Advanced Rectal Cancer]. ( Hashimoto, Y; Hirata, Y; Ishizaki, Y; Kitamura, S; Kuga, Y; Miwata, T; Mouri, T, 2017)
"Distal resection margin (≤5 vs >5 mm) did not show any significant difference in cumulative incidence of locoregional recurrence (P=."1.46Continuous Effect of Radial Resection Margin on Recurrence and Survival in Rectal Cancer Patients Who Receive Preoperative Chemoradiation and Curative Surgery: A Multicenter Retrospective Analysis. ( Bae, JM; Jang, HS; Jeong, S; Kim, SH; Lee, JH; Lee, JW; Nam, TK; Song, JH; Sung, S, 2017)
"Locally advanced rectal cancer (LARC) is frequently treated with neoadjuvant chemoradiotherapy (NACRT) to reduce the risk of local recurrence and improve survival."1.46Prognostic significance of tumour regression grade after neoadjuvant chemoradiotherapy for a cohort of patients with locally advanced rectal cancer: an 8-year retrospective single-institutional study. ( Cai, S; Chen, Y; Lin, G; Lu, J; Qiu, H; Sun, X; Wu, B; Xiao, T; Xiao, Y; Xu, L; Zhou, W, 2017)
"Patients with ypT0-3N0 rectal cancer after preoperative CRT and TME were included using prospectively collected tumor registry cohort between January 2001 and December 2013."1.46Role of adjuvant chemotherapy in locally advanced rectal cancer with ypT0-3N0 after preoperative chemoradiation therapy and surgery. ( Ahn, JB; Beom, SH; Choe, EA; Heo, SJ; Hur, H; Jung, I; Jung, M; Kim, C; Kim, CG; Kim, H; Kim, JH; Kim, NK; Koom, WS; Min, BS; Park, HS; Shin, SJ, 2017)
"To investigate the association between polymorphisms of DNA repair genes and xenobiotic with acute adverse effects in locally advanced rectal cancer patients treated with neoadjuvant radiochemotherapy."1.46Potential Role of Single Nucleotide Polymorphisms of XRCC1, XRCC3, and RAD51 in Predicting Acute Toxicity in Rectal Cancer Patients Treated With Preoperative Radiochemotherapy. ( Agolli, L; Borro, M; Bracci, S; De Sanctis, V; Di Nardo, F; Enrici, RM; Falco, T; Gentile, G; Maglio, M; Minniti, G; Nicosia, L; Osti, MF; Simmaco, M; Valeriani, M, 2017)
"Rectal cancer is a malignant disease requiring multidisciplinary management."1.46Management of rectal cancer: the 2016 French guidelines. ( Bridoux, V; Brouquet, A; de Chaisemartin, C; Kirzin, S; Lakkis, Z; Lefevre, JH; Maggiori, L; Manceau, G; Panis, Y, 2017)
"Patients with locally advanced rectal cancer (LARC) receiving neoadjuvant chemoradiation (nCRT) can have a complete pathologic response (pCR), and are given postoperative adjuvant chemotherapy (ACT)."1.46Is routine use of adjuvant chemotherapy for rectal cancer with complete pathological response justified? ( Church, JM; Gamaleldin, M; Gorgun, E; Kalady, M; Liska, D; Stocchi, L, 2017)
"Patients with ypN0 rectal cancer who have received preoperative chemoradiotherapy can be divided into those who initially were node negative and those whose positive nodes have been sterilized by preoperative therapy."1.46Prognostic Value of Sterilized Lymph Nodes After Preoperative Chemoradiotherapy for Patients with ypN0 Rectal Cancer. ( Agostini, J; Benoist, S; Boige, V; Brouquet, A; Dartigues, P; Dumont, F; Goéré, D; Julié, C; Lazure, T; Penna, C; Peschaud, F; Vychnevskaia, K, 2017)
"A total of 198 patients with rectal cancer underwent preoperative endoscopic assessments after chemoradiotherapy."1.46Prediction of Pathological Complete Response Using Endoscopic Findings and Outcomes of Patients Who Underwent Watchful Waiting After Chemoradiotherapy for Rectal Cancer. ( Fukayama, M; Hata, K; Ishihara, S; Kawai, K; Kiyomatsu, T; Morikawa, T; Nozawa, H; Watanabe, T, 2017)
"In pathological stage N2 rectal cancer patients, administering adjuvant chemotherapy before chemoradiotherapy led to a lower rate of treatment failure, especially with respect to distant metastasis."1.46Patients with pathological stage N2 rectal cancer treated with early adjuvant chemotherapy have a lower treatment failure rate. ( Fang, H; Feng, YR; Jin, J; Li, N; Li, YX; Liu, XF; Liu, YP; Ren, H; Song, YW; Tang, Y; Wang, SL; Wang, WH; Wang, X; Yu, ZH, 2017)
"The rate of ypCR in advanced rectal cancer was about 10%."1.43The outcome and the frequency of pathological complete response after neoadjuvant radiotherapy in curative resections for advanced rectal cancer: a population-based study. ( Rekstad, LC; Tranø, G; Wasmuth, HH, 2016)
"The patient was diagnosed with thrombotic thrombocytopenic purpura and treated with a plasma exchange."1.43[A Case of Thrombotic Thrombocytopenic Purpura in a Patient Undergoing FOLFOX6 plus Panitumumab Therapy for Unresectable Recurrent Rectal Cancer with a Rapidly Progressive Course]. ( Hatano, Y; Ishibashi, M; Kato, K; Konda, R; Michishita, Y; Nozawa, T; Oyama, K; Sasaki, A, 2016)
"In patients with rectal cancer who have already received neoadjuvant chemoradiotherapy and undergone curative resection, adding oxaliplatin to 5-FU could prolong OS in patients aged < 73 years and ypN+ category."1.43Impact of age on efficacy of postoperative oxaliplatin-based chemotherapy in patients with rectal cancer after neoadjuvant chemoradiotherapy. ( Chen, XW; Gao, P; Huang, XZ; Ma, B; Song, YX; Sun, JX; Wang, J; Wang, ZN; Zhao, JH, 2016)
"Fifty patients with rectal cancer undergoing neoadjuvant (chemo)radiotherapy and surgery were included in the study."1.43NF-κB/p65 expression before and after treatment in rectal cancer patients undergoing neoadjuvant (chemo)radiotherapy and surgery: prognostic marker for disease progression and survival. ( Dvorak, J; Fanta, J; Kubecova, M; Rychterova, V; Voboril, R; Voborilova, J, 2016)
"Neoadjuvant RT for rectal cancer has lasting effects on the pelvic BM, which are demonstrable during adjuvant OxF."1.43Long-Term Bone Marrow Suppression During Postoperative Chemotherapy in Rectal Cancer Patients After Preoperative Chemoradiation Therapy. ( Baby, R; Chen, T; Jabbour, SK; Lu, SE; Moss, RA; Newman, NB; Nissenblatt, MJ; Sidhu, MK, 2016)
"The effect of individual dose adjustment of 5-fluorouracil (5-FU) based on pharmacokinetic monitoring on the outcome of FOLFOX for metastatic colorectal cancer was analyzed retrospectively."1.43[Individual Dose Adjustment of 5-Fluorouracil Based on Pharmacokinetic Monitoring May Improve the Outcome of FOLFOX for Metastatic Colorectal Cancer]. ( Kanda, J; Muneoka, K; Sakata, J; Sasaki, M; Shirai, Y; Wakabayashi, H; Wakai, T, 2016)
"The mean recurrence-free survival was 13."1.43[Adjuvant Systemic Chemotherapy with S-1/Oxaliplatin or mFOLFOX6 after Curative Resection of Distant Metastases in Patients with Colorectal Cancer]. ( Amada, E; Baba, S; Kameyama, N; Mitsuhashi, H; Miyata, R; Tomita, M, 2016)
"Here, we present a case of rectal cancer that became curatively resectable after preoperative chemotherapy with mFOLFOX6 plus c-mab."1.43[A Case of an Unresectable Locally Advanced Rectal Cancer with Surrounding Organ Invasion Successfully Resected after Chemotherapy with mFOLFOX6 plus Cetuximab]. ( Ariake, K; Doi, T; Takagi, H; Takemura, S, 2016)
"Distant metastasis occurred in 86."1.43[Analysis of risk factors of distant metastasis in rectal cancer patients who received total mesorectal excision following neoadjuvant chemoradiotherapy]. ( Chi, P; Huang, S; Huang, Y; Lin, H; Lu, X; Sun, Y; Wang, X; Xu, Z; Ye, D, 2016)
"The histological diagnosis was tubular adenocarcinoma (tub2-1), int, INF a, pMP, ly0, v0, pDM0, pPM0, R0."1.43[A Case of Advanced Rectal Cancer Resected Successfully after Induction Chemotherapy with Modified FOLFOX6 plus Panitumumab]. ( Aomatsu, N; Dozaiku, T; Hanno, H; Hirakawa, T; Hirooka, T; Iwauchi, T; Kawamura, M; Morimoto, J; Nakazawa, K; Nishii, T; Takayanagi, S; Takeda, O; Takeuchi, K; Uchima, Y; Yukawa, Y, 2016)
"Between 2006 and 2015, patients with rectal cancer, stages I-III, without metastasis, treated with neoadjuvant CRT/CT, who had clinical complete response were included."1.43Non-surgical management of rectal cancer. Series of 68 cases, long follow up in two leading centres in Argentina. ( Chacon, M; Coraglio, M; Dieguez, A; Huertas, E; Iseas, S; Mariani, J; Mendez, G; O'Connor, JM; Pairola, A; Roca, E; Sanchez Loria, F, 2016)
"Radical resected rectal cancer specimens and clinicopathological data of 105 patients, including 60 men and 45 women with median age of 59 years, diagnosed as locally advanced rectal cancer in Peking Union Medical College Hospital from January 2008 to December 2014 were collected retrospectively."1.43[Expression of CD133 in rectal cancer tissues and its relationship with neoadjuvant chemoradiotherapy]. ( Feng, R; Li, D; Luo, Y; Wu, H; Xiao, Y; Zhong, D, 2016)
"Data were validated in the rectal cancer cohort treated in the neoadjuvant setting."1.43Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer. ( Bacon, O; Carberry, S; Concannon, CG; Fay, J; Hector, S; Kay, EW; Lindner, AU; McCawley, N; McNamara, DA; Murphy, ÁC; Prehn, JH; Ryan, D, 2016)
"Many patients with rectal cancer undergo preoperative neoadjuvant chemoradiation, with approximately 70% exhibiting pathologic downstaging in response to treatment."1.43Genetic polymorphisms in 5-Fluorouracil-related enzymes predict pathologic response after neoadjuvant chemoradiation for rectal cancer. ( Carter, JV; Eichenberger, MR; Galandiuk, S; Nelson, B; Netz, U, 2016)
"Abdominal CT revealed Fournier's gangrene caused by small intestinal perforation."1.43[A Case of Fournier's Gangrene Caused by Small Intestinal Perforation during Bevacizumab Combination Chemotherapy]. ( Furukawa, J; Ishida, T; Kato, S; Kimata, M; Kobayashi, K; Kobayashi, T; Matsumoto, K; Ogata, Y; Ozawa, H; Sasakura, Y; Shimizu, T; Shinozaki, H; Terauchi, T; Wakabayashi, T, 2016)
"Overall and rectal cancer-specific survival were calculated by the Kaplan-Meier method."1.43DNA Mismatch Repair Deficiency in Rectal Cancer: Benchmarking Its Impact on Prognosis, Neoadjuvant Response Prediction, and Clinical Cancer Genetics. ( Bednarski, B; Borras, E; Chang, GJ; de Rosa, N; Feig, BW; Krishnan, S; Lynch, PM; Messick, CA; Rodriguez-Bigas, MA; Skibber, JM; Veerapong, J; Vilar, E; You, YN, 2016)
"To compare the short-term efficacy and treatment-related adverse reaction between preoperative three dimensional conformal radiotherapy (3D-CRT) and volumetric modulated arc therapy (VMAT) concurrently combined with chemotherapy in the treatment of locally advanced rectal carcinoma (LARC)."1.43[Short-term efficacy comparison between preoperative three dimensional conformal radiotherapy and volumetric modulated arc therapy concurrently combined with chemotherapy in the treatment of locally advanced rectal carcinoma]. ( Gao, Y; Liu, M; Xiao, L; Xiao, W; Yu, X; Zeng, Z; Zhang, R; Zhu, Y, 2016)
"A 68-year-old man was diagnosed with rectal cancer on colonoscopy and liver metastasis of rectal cancer on abdominal computed tomography(CT)."1.43[A Case of Liver Metastasis from Colorectal Cancer That Showed a Pathological Complete Response to mFOLFOX6 plus Cetuximab]. ( Chihara, T; Endo, S; Ikenaga, M; Konishi, K; Nakagawa, T; Nakashima, S; Nishijima, J; Ohta, K; Yamada, T, 2016)
"After local excision of early rectal cancer, revision radical resection is recommended for patients with high-risk pathologic stage T1 (pT1) or pT2 cancer, but the revision procedure has high morbidity rates."1.43Adjuvant chemoradiotherapy instead of revision radical resection after local excision for high-risk early rectal cancer. ( Ahn, SJ; Chung, WK; Jeong, JU; Kim, HR; Kim, YH; Nam, TK; Shim, HJ; Song, JY; Yoon, MS, 2016)
"Adjuvant chemotherapy for resected rectal cancer is widely used."1.43Adjuvant treatment for resected rectal cancer: impact of standard and intensified postoperative chemotherapy on disease-free survival in patients undergoing preoperative chemoradiation-a propensity score-matched analysis of an observational database. ( Benckert, C; Benedix, F; Bruns, C; Garlipp, B; Gastinger, I; Lippert, H; Otto, R; Popp, F; Ptok, H; Ridwelski, K, 2016)
"For patients with locally advanced rectal cancer (LARC) treated with preoperation chemoradiation (pCRT), identifying differentially expressed (DE) genes between non-responders and responders is a common approach for investigating mechanisms of chemoradiation resistance."1.43Discriminating cancer-related and cancer-unrelated chemoradiation-response genes for locally advanced rectal cancers. ( Ao, L; Cai, H; Cheng, J; Gao, Q; Guan, Q; Guo, Y; Guo, Z; Jiang, W; Li, X; Yan, H; Zhang, J, 2016)
"We report 2 cases of metastatic rectal cancer patients who received chemotherapy with FOLFOXIRI plus bevacizumab(Bev)."1.43[Two Cases of Metastatic Rectal Cancer Patients Who Received Chemotherapy with FOLFOXIRI plus Bevacizumab]. ( Aomatsu, N; Hirakawa, T; Iwauchi, T; Morimoto, J; Nagashima, D; Nakazawa, K; Nishii, T; Takeuchi, K; Tei, S; Uchima, Y; Wang, E; Yamakoshi, Y, 2016)
"Local recurrence was diagnosed 5 years and 4 months after the operation."1.43[A Patient with Colon Cancer Local Site Recurrence Who Experienced Difficulty Tolerating Intensive Chemotherapy Was Treated Effectively with sLV5FU2 Therapy]. ( Fukunaga, M; Honda, S; Kobayashi, K; Konishi, K; Miki, H; Okada, K; Ota, H; Saito, A; Tokuyama, S; Yokoyama, S; Yoshioka, S; Yukimoto, R, 2016)
"Of the 19 patients with Stage IV rectal cancer, 15 (79%) had liver surgery with curative intent."1.42Pathological response of locally advanced rectal cancer to preoperative chemotherapy without pelvic irradiation. ( Benoist, S; Bensignor, T; Brouquet, A; Dariane, C; Julié, C; Lazure, T; Nordlinger, B; Penna, C; Thirot-Bidault, A, 2015)
"For patients with locally advanced rectal cancer, higher radiation dose may contribute to the improvement of both LC and disease-free survival, without significantly increasing the incidence of acute and long-term complications compared with adjuvant chemoradiotherapy alone."1.42Adjuvant chemoradiation plus intraoperative radiotherapy versus adjuvant chemoradiation alone in patients with locally advanced rectal cancer. ( Fu, S; Huang, G; Li, P; Lu, JJ; Peng, L; Tey, J; Xiong, F; Yang, Z; Zhang, Q, 2015)
" It was designed to answer five research questions relating to safety, dosage and administration, and discontinuation from capecitabine-based adjuvant therapy."1.42Observational study of adjuvant therapy with capecitabine in colon cancer. ( Guggenberger, D; Hansen, R; Jacobs, G; Kröning, H; Schardt, C; Schmidt, P; Steffens, CC; Tschechne, B; Valdix, AR; Wohlfarth, T, 2015)
"In recent decades, the management of rectal cancer has been significantly improved by optimizing the surgical treatment with the total mesorectal excision and the development of neoadjuvant radiotherapy with or without chemotherapy."1.42[Preoperative chemoradiotherapy for rectal cancer: experience from one centre]. ( Bednarek, C; Bosset, JF; Cerda, T; Guimas, V; Lepinoy, A; Lescut, N; Schipman, B, 2015)
"Thirteen patients with colon cancer and 7 patients with rectal cancer were enrolled after curative surgery."1.42[The present status of CapeOX as adjuvant chemotherapy for colorectal cancer]. ( Ishii, K; Kanamoto, A; Miyanaga, S; Noto, M; Takeda, T; Tani, T; Yagi, M, 2015)
"Locally advanced rectal cancer patients who received neoadjuvant chemoradiotherapy following radical resection were retrospectively assessed for tumor response during 2005 to 2014 from the database of colorectal cancer."1.42[Predictive value of preoperative imaging and postoperative pathology on clinical complete response after neoadjuvant chemoradiation for locally advanced rectal cancer]. ( Du, X; Lin, G; Qiu, H; Wu, B; Xiao, Y; Xu, L; Xue, H; Zhang, G; Zhong, G; Zhou, W, 2015)
"The mainstay of treatment in rectal cancer is neoadjuvant radio chemotherapy prior to surgery, in an attempt to downstage the tumour, allowing for more complete removal during surgery."1.42High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer. ( Bacon, O; Deasy, J; Fay, J; Flanagan, L; Kay, EW; Kehoe, J; Lindner, AU; McNamara, DA; Prehn, JH, 2015)
"Primary rectal cancer patients with synchronous distant metastases between September 2001 and August 2011 were enrolled."1.42Comparison of oncologic outcomes of metastatic rectal cancer patients with or without neoadjuvant chemoradiotherapy. ( Jung, SH; Kim, JH; Kim, SH, 2015)
"In most institutions, locally advanced rectal cancer is treated with neoadjuvant chemoradiotherapy followed by surgery 6-8 weeks later, allowing time for tumor response and recovery from chemoradiotherapy-related toxicities."1.42The outcome of 5-fluorouracil chemotherapy after the completion of neoadjuvant chemoradiotherapy, administered until 2 weeks before rectal cancer resection. ( Chang, PK; Chiang, MH; Hsiao, CW; Jao, SW; Lee, CC; Lee, TY; Wu, CC, 2015)
"Locally advanced rectum cancer patients experience good results with surgery and adjuvant concurrent chemoradiation."1.42Long Term Outcomes of Preoperative versus Postoperative Concurrent Chemoradiation for Locally Advanced Rectal Cancer: Experience from Ramathibodi Medical School in Thailand. ( Boonyawan, K; Chansriwong, P; Dangprasert, S; Darunikorn, P; Dhanachai, M; Jiarpinitnun, C; Pattaranutaporn, P; Puataweepong, P; Sitathanee, C; Swangsilpa, T, 2015)
"This was a rare case of rectal cancer with submucosal invasion that showed recurrence in the bone and lymph nodes 78 months after the additional resection."1.42[Recurrence of Rectal Cancer with Submucosal Invasion in the Bone and Lymph Nodes 89 Months after Surgery--A Case Report]. ( Amikura, K; Asayama, M; Fukuda, T; Ishikawa, H; Kawashima, Y; Kazama, S; Kurozumi, M; Mori, Y; Nishimura, Y; Nishizawa, Y; Sakamoto, H; Takano, M; Takenoya, T; Tanaka, Y, 2015)
"We describe a case of perforated rectal cancer that became curatively resectable after FOLFOX4 chemotherapy."1.42[Conversion Therapy of Initially Unresectable Rectal Cancer with Perforation via FOLFOX4 Chemotherapy]. ( Fujita, Y; Ishikawa, F; Ito, H; Kamata, S; Nitta, H; Omoto, H; Yamada, C, 2015)
"A patient in his 70s was diagnosed with rectal cancer (pT3, pN1, cM0, and pStage IIIa) for which he underwent low anterior resection of the rectum and received adjuvant therapy with UFT/LV."1.42[A Case of Rectal Cancer with Multiple Liver, Lung, and Para-Aortic Lymph Node Metastases Successfully Treated with FOLFOX4 plus Bevacizumab]. ( Goya, T; Hanaka, J; Kanamura, S; Nakayama, H; Takahashi, M; Takahashi, S; Wakamatsu, T, 2015)
"Adverse events seen with chemotherapy consisted of grade 2 leukopenia in 1 patient, but there were no cases of delayed administration or dosage reduction due to grade 2 neurotoxicity."1.42Evaluation of Preoperative Chemotherapy with Modified OPTIMOX-1 Plus Bevacizumab in Patients with Advanced Rectal Cancer with Factors Contraindicative of Curative Surgery. ( Arimitsu, H; Hirano, A; Koda, K; Kosugi, C; Matsuo, K; Shiragami, R; Shuto, K; Suzuki, M; Tanaka, K; Yamazaki, M; Yasuda, H, 2015)
"Recurrent rectal cancer appears radioresistant compared with primary tumors for tumor size after CRT."1.40Chemoradiotherapy response in recurrent rectal cancer. ( Bhangu, A; Brown, G; Tait, DM; Tekkis, P; Wotherspoon, A; Yu, SK, 2014)
"The presented patient with stage IV rectal cancer and liver metastases was in a unique situation linked to its inclusion in a reversed treatment and the use of neoadjuvant chemotherapy alone."1.40Complete pathological response (ypT0N0M0) after preoperative chemotherapy alone for stage IV rectal cancer. ( Gervaz, P; Mentha, G; Morel, P; Naiken, SP; Roth, A; Rubbia-Brandt, L; Thomopoulos, T; Toso, C, 2014)
"Metastasized rectal cancer has long been considered incurable."1.40A clinical study of metastasized rectal cancer treatment: assessing a multimodal approach. ( Albertsson, M; Holmqvist, A; Jung, M; Sun, XF, 2014)
"Patients with cT2-4N0-2M0 distal rectal cancer treated with CRT (50."1.40Local recurrence after complete clinical response and watch and wait in rectal cancer after neoadjuvant chemoradiation: impact of salvage therapy on local disease control. ( Gama-Rodrigues, J; Habr-Gama, A; Lynn, PB; Perez, RO; Proscurshim, I; Sabbagh, C; São Julião, GP, 2014)
"Patients with T4 or lymph node-positive rectal cancer were treated with three cycles of XELOX plus bevacizumab and one additional cycle of XELOX."1.40Neoadjuvant capecitabine and oxaliplatin (XELOX) combined with bevacizumab for high-risk localized rectal cancer. ( Doki, Y; Fujie, Y; Fujii, M; Hasegawa, J; Ikeda, M; Kato, T; Kim, HM; Miwa, H; Miyake, Y; Mizushima, T; Mori, M; Nezu, R; Nishimura, J; Noura, S; Sekimoto, M; Takemasa, I; Takemoto, H; Tamagawa, H; Yamamoto, H, 2014)
"She had been diagnosed with idiopathic thrombocytopenic purpura (ITP) in her 20s, with a platelet count maintained at approximately 1."1.40[Concomitant use of romiplostim and chemotherapy for advanced rectal cancer associated with idiopathic thrombocytopenic purpura]. ( Fujinaga, T; Hiramatsu, N; Iijima, H; Nishida, T; Shinzaki, S; Takehara, T; Tatsumi, T; Tsujii, M; Yakushijin, T; Yamada, M; Yamada, T, 2014)
"NACRT before major rectal cancer surgery significantly decreased physical fitness as assessed by CPET."1.40The effects of neoadjuvant chemoradiotherapy on physical fitness and morbidity in rectal cancer surgery patients. ( Barben, CP; Grocott, MP; Jack, S; Kemp, GJ; Loughney, L; Sripadam, R; West, MA, 2014)
"Radiotherapy for advanced rectal cancer is an important treatment to reduce local recurrence."1.40Late complications after proctectomy in rectal cancer patients who underwent radiotherapy. ( Jung, SH; Kim, JH; Kim, SH, 2014)
"Patients with T3/T4 and or N+ rectal cancer (n = 65) were treated with preoperative concomitant boost radiotherapy (55 Gy/25 fractions) associated to concurrent chemotherapy with oral capecitabine."1.40Neoadjuvant chemoradiation with concomitant boost radiotherapy associated to capecitabine in rectal cancer patients. ( Agolli, L; Bracci, S; De Sanctis, V; Falco, T; Masoni, L; Maurizi Enrici, R; Osti, MF; Valeriani, M, 2014)
"Rectal cancer was detected up to 13 cm proximal to the anal verge."1.40[A case of advanced rectal cancer that showed complete response to the addition of XELOX+bevacizumab therapy to preoperative chemoradiotherapy with S-1/CPT-11]. ( Konno, F; Matsumoto, H; Mitsui, K; Namiki, K; Takahashi, T; Yoshida, R, 2014)
"Postoperative complications were graded according to the Clavien-Dindo classification."1.40Prognostic factors for postoperative morbidity and tumour response after neoadjuvant chemoradiation followed by resection for rectal cancer. ( Berkel, AE; Klaase, JM; van der Palen, J; Woutersen, DP, 2014)
"Patients with locally advanced rectal cancer (LARC) have a dismal prognosis."1.40Post-chemoradiation intraoperative electron-beam radiation therapy boost in resected locally advanced rectal cancer: long-term results focused on topographic pattern of locoregional relapse. ( Alvarez, E; Calvo, FA; Del Valle, E; Deutsch, E; Garcia-Alfonso, P; García-Sabrido, JL; Muñoz-Calero, A; Peligros, I; Rivera, S; Rodriguez, M; Serrano, J; Sole, CV; Turégano, F, 2014)
"Aberrant expression of MRP3 in rectal cancer confers chemo-radioresistance."1.40Multidrug resistance-associated protein 3 confers resistance to chemoradiotherapy for rectal cancer by regulating reactive oxygen species and caspase-3-dependent apoptotic pathway. ( Cao, G; Fu, C; Gong, H; Wang, H; Xing, J; Yu, E; Yu, Z; Zhang, C; Zhang, W; Zhang, X, 2014)
"Locally advanced rectal cancers are currently treated with neoadjuvant concurrent chemoradiotherapy (CCRT) followed by surgery, but stratification of risk and final outcomes remain suboptimal."1.40Overexpression of CPS1 is an independent negative prognosticator in rectal cancers receiving concurrent chemoradiotherapy. ( Chen, TJ; Hsing, CH; Lee, SW; Lee, YY; Li, CF; Lin, CY; Lin, LC; Sheu, MJ; Wu, TF, 2014)
"We examined the outcomes of transanal endoscopic microsurgery excisions with entry into the peritoneal cavity and compared them with those that did not to address our hypothesis that entry is safe with no ill infectious or oncological consequences."1.40Transanal endoscopic microsurgery with entrance into the peritoneal cavity: is it safe? ( D'Andrea, AP; Frenkel, JL; Greenleaf, CE; Marks, JH, 2014)
"Computed tomography showed intussusception caused by a large tumor in the pelvis and absence of distant metastases."1.40Intussusception due to rectal adenocarcinoma in a young adult: a case report. ( Fujiwara, T; Inada, R; Kishimoto, H; Kondo, Y; Mori, Y; Nagasaka, T; Toshima, T, 2014)
"We analyzed 120 rectal cancer patients treated with neoadjuvant pelvic radiotherapy (PRT) with concurrent 5-fluorouracil-based chemotherapy."1.40Clinical and dosimetric predictors of acute hematologic toxicity in rectal cancer patients undergoing chemoradiotherapy. ( Apte, A; Deasy, JO; Goodman, KA; Oh, JH; Son, CH; Yang, TJ, 2014)
"We report a case of rectal cancer, which was successfully treated with radical resection and neoadjuvant chemoradiotherapy."1.40[Efficiency of pre-operative chemoradiotherapy in treating a case of advanced rectal cancer]. ( Ami, K; Ando, M; Arai, K; Gokita, K; Hayasaka, J; Imai, K; Kitazume, A; Kondou, M; Okamoto, E; Shibayama, T; Takagi, K; Tamura, A; Tei, S; Watanabe, A, 2014)
"Herein, we present a case of advanced rectal cancer surgically resected after chemotherapy."1.40[Surgical resection after chemotherapy for advanced rectal cancer - report of a case]. ( Kameyama, H; Kobayashi, T; Kosugi, S; Koyama, Y; Minagawa, M; Nogami, H; Sakata, J; Shimada, Y; Suda, K; Wakai, T, 2014)
"The patient declined surgery for recurrence so radiotherapy was planned."1.40[Irradiation with carbon ions for locally recurrent rectal cancer]. ( Akita, H; Fujino, S; Fujiwara, Y; Fukata, T; Gotoh, K; Kishi, K; Marubashi, S; Miyoshi, N; Motoori, M; Noura, S; Ohue, M; Sakon, M; Sugimura, K; Takahashi, H; Yano, M, 2014)
"A colonoscopy detected KRAS wild-type rectal cancer."1.40[A case of stage IV rectal cancer successfully resected after chemotherapy (mFOLFOX6 plus panitumumab)]. ( Aisu, Y; Ando, Y; Asao, Y; Furuyama, H; Honda, K; Kadokawa, Y; Kato, S; Machimoto, T; Nishino, H; Nishiuchi, A; Yoshimura, T, 2014)
"A 69- year-old man with metastatic rectal cancer received 4 courses XELOX therapy."1.40[A case of metastatic rectal cancer with fulminant hepatitis caused by XELOX therapy]. ( Egawa, T; Ito, Y; Kemmochi, T; Makino, H; Nagashima, A; Ohkubo, Y; Shimokawa, R; Suzuki, Y; Yamamuro, W; Yoneda, M, 2014)
"Stage III rectal cancer was found in 64."1.39Prognosis factors for recurrence in patients with locally advanced rectal cancer preoperatively treated with chemoradiotherapy and adjuvant chemotherapy. ( Arbea, L; Arredondo, J; Baixauli, J; Beorlegui, C; Chopitea, A; Hernández-Lizoáin, JL; Rodríguez, J; Sola, JJ, 2013)
"Postoperative complications have had occurred in 12."1.39[Immediate results of complex treatment of resectable rectal neoplasms of distal localization]. ( Basheev, VKh; Bondar', GV; Sovpel', IV; Sovpel', OV; Zolotukhin, SÉ, 2013)
"Twenty-five patients with T3/T4N0 or N+ rectal cancer were enrolled."1.39Feasibility of an adaptive strategy in preoperative radiochemotherapy for rectal cancer with image-guided tomotherapy: boosting the dose to the shrinking tumor. ( Broggi, S; Calandrino, R; De Cobelli, F; De Nardi, P; Di Muzio, N; Di Palo, S; Fiorino, C; Iacovelli, NA; Losio, C; Orsenigo, E; Passoni, P; Ricci, V; Ronzoni, M; Slim, N; Staudacher, C; Tamburini, A, 2013)
"Management of locally advanced rectal cancer is complex because curative treatment routinely involves administration of surgery, chemotherapy, and radiation."1.39Evolving role of neoadjuvant therapy in rectal cancer. ( Schrag, D, 2013)
"After local pelvic recurrence, she underwent radiation therapy(50 Gy in total), and then chemotherapy(XELOX+bevacizumab)was started."1.39[A case of necrotizing fasciitis developed in a patient with recurrent rectal cancer treated with chemotherapy]. ( Arisawa, Y; Chiba, N; Hashimoto, M; Ishii, M; Ishikawa, S; Nakamura, T; Shimada, A, 2013)
"We report a case of advanced rectal cancer treated with chemotherapy, for which laparoscopic splenectomy had been effective for thrombocytopenia."1.39[Successful management using laparoscopic splenectomy for splenomegaly and thrombocytopenia caused by oxaliplatin-based chemotherapy for advanced rectal cancer]. ( Arita, S; Koike, N; Ohshima, Y; Shinozaki, E; Takeuchi, T, 2013)
"A total of 507 patients with rectal cancer underwent RT at HKL."1.39Preoperative long course chemoirradiation in a developing country for rectal carcinoma: Kuala Lumpur hospital experience. ( Lau, FN; Lee, WC; Phua, VC; Yusof, MM, 2013)
"Eighteen patients with rectal cancer and synchronous liver metastases, who had undergone laparoscopic colorectal resection and simultaneous treatment for liver metastases, were retrospectively reviewed."1.39The preliminary experience in simultaneous treatment of rectal cancer and synchronous liver metastases with laparoscopy. ( Chen, F; Chen, K; Ding, XM; Hu, BS; Leng, JJ; Tan, HM; Tan, JW; Zhu, Z, 2013)
"Fecal incontinence was assessed by patient self-reported data without the use of a validated score."1.39Cumulative incidence of permanent stoma after sphincter preserving low anterior resection of mid and low rectal cancer. ( Buchner, S; Dinnewitzer, A; Jäger, T; Nawara, C; Öfner, D; Wolfgang, H, 2013)
"Of all patients operated for rectal cancer, 27."1.39Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications. ( Fietkau, R; Gock, M; Klar, E; Klautke, G; Prall, F; Rau, B; Schiffmann, L; Wedermann, N, 2013)
" The clinical efficacy and bevacizumab-related adverse reactions were observed."1.39[Efficacy and safety of bevacizumab (BEV) plus chemotherapeutic agents in the treatment of metastatic colorectal cancer, mCRC]. ( Chen, Y; Cui, YH; Guo, X; Liu, TS; Yu, YY; Zhou, YH; Zhuang, RY, 2013)
"The 3-year local recurrence and distant metastasis rates in the adjuvant chemotherapy group were 4."1.39[Value of postoperative adjuvant chemotherapy in locally advanced rectal cancer patients with ypT1-4N0 after neo-adjuvant chemoradiotherapy]. ( Chang, H; Chen, L; Du, XJ; Gao, YH; Liu, MZ; Peng, HH; Wen, BX; Xiao, L; You, KY; Zeng, ZF; Zhou, GQ, 2013)
"A 69-year-old man diagnosed with lower rectal cancer was referred to our hospital."1.39[A case of pathological complete response with neoadjuvant mFOLFOX6 chemotherapy for advanced lower rectal cancer]. ( Fujiwara, Y; Gotoh, K; Ishikawa, O; Kishi, K; Marubashi, S; Motoori, M; Noura, S; Ohigashi, H; Ohue, M; Shingai, T; Sueda, T; Takahashi, H; Tomita, Y; Yano, M, 2013)
"In cases of advanced rectal cancer, preoperative chemoradiotherapy( CRT) serves to improve the local control rate, survival rate, radical resection rate, and/or probability of sphincter muscle preservation."1.39[A case of successful radical resection of rectal cancer with neo-adjuvant chemoradiotherapy]. ( Amagasa, H; Ami, K; Ando, M; Arai, K; Fujiya, K; Fukuda, A; Ganno, H; Gokita, K; Imai, K; Kamikozuru, H; Kawai, Y; Nagahama, T; Okada, Y; Seki, R; Takasaki, J; Takeuchi, S; Tei, S, 2013)
"Colonoscopy revealed a lower rectal cancer just above the dentate line, and its biopsy showed endocrine cell carcinoma."1.39[A case of rectal endocrine cell carcinoma treated by laparoscopic assisted intersphincteric resection after neoadjuvant chemotherapy]. ( Arai, S; Kataoka, M; Miyazawa, K; Oeda, Y; Shiobara, M; Tonooka, T; Wakatsuki, K; Yoshioka, S, 2013)
"We encountered a case of colorectal cancer with pelvic abscess treated with radical surgery following colostomy and chemotherapy."1.39[A case of locally advanced colorectal cancer with abscess responding to 5-fluorouracil, leucovorin, and oxaliplatin plus bevacizumab]. ( Goseki, N; Kuwabara, H; Liu, B; Mitsuoka, A; Nakajima, K; Sanada, T; Watanabe, S, 2013)
" Grade ≥3 adverse events (AEs) that occurred during 5-FU/RT and during combined 5-FU/RT + mFOLFOX-6 were recorded."1.39Gene polymorphisms predict toxicity to neoadjuvant therapy in patients with rectal cancer. ( Chen, Z; Duldulao, MP; Garcia-Aguilar, J; Ho, J; Kim, J; Le, M; Lee, W; Li, W; Nelson, RA, 2013)
"In locally advanced rectal cancer (LARC) patients, major response to neoadjuvant radiotherapy (NR) has been associated with favorable long-term outcomes."1.39What is the incidence of metastatic lymph node involvement after significant pathologic response of primary tumor following neoadjuvant treatment for locally advanced rectal cancer? ( Flejou, JF; Lefèvre, JH; Parc, Y; Svrcek, M; Tiret, E; Tranchart, H, 2013)
"Patients with small residual tumors (≤3 cm) radiologically staged ycT0-2N0 were treated by transanal endoscopic microsurgery."1.39Transanal endoscopic microsurgery for residual rectal cancer (ypT0-2) following neoadjuvant chemoradiation therapy: another word of caution. ( Bianchi, R; Gama-Rodrigues, J; Habr-Gama, A; Lynn, PB; Perez, RO; Proscurshim, I; São Julião, GP, 2013)
"The ulcer was relieved by conservative medical treatment."1.39[A case of an ulcer of the sigmoid colon during chemotherapy with FOLFOX4 and bevacizumab for recurrence of rectal carcinoma]. ( Hirata, K; Mizushima, Y; Okuya, K, 2013)
"We report a case of advanced rectal cancer with bladder carcinoma."1.39[A case of advanced rectal cancer with bladder carcinoma salvaged from myocardial infarction during operation, showing tumor regression by XELOX treatment, good quality of life]. ( Kodama, M; Mekata, E; Okumura, K; Shiogai, Y; Tani, S; Tani, T, 2013)
"A 59-years-old woman with metastatic rectal cancer treated with bevacizumab, who developed low back pain after 11 cycles of chemotherapy."1.38Perirenal hematoma associated with bevacizumab treatment. ( Hayashi, H; Nakagawa, K; Okamoto, I, 2012)
"A total of 93 Stage II-III rectal cancer patients were genotyped using peripheral blood samples."1.38X-ray cross-complementing group 1 and thymidylate synthase polymorphisms might predict response to chemoradiotherapy in rectal cancer patients. ( Anido, U; Balboa, E; Barros, F; Bernardez, B; Carracedo, A; Duran, G; Gomez, A; Lamas, MJ; Lopez, R; Rana-Diez, P, 2012)
"Carcinomas were categorized by MRI as mucinous (mucin proportion >50% within the tumor volume), and as nonmucinous."1.38Rectal cancer: mucinous carcinoma on magnetic resonance imaging indicates poor response to neoadjuvant chemoradiation. ( Düber, C; Hansen, T; Heintz, A; Hötker, AM; Junginger, T; Kreft, A; Kreitner, KF; Menig, M; Oberholzer, K; Schmidberger, H; Schneider, A, 2012)
"To evaluate the efficacy and treatment-related toxicity of accelerated hyperfractionation field-involved re-irradiation combined with concurrent capecitabine chemotherapy for locally recurrent and irresectable rectal cancer (LRIRC)."1.38Accelerated hyperfractionation field-involved re-irradiation combined with concurrent capecitabine chemotherapy for locally recurrent and irresectable rectal cancer. ( Dai, Y; Li, L; Shao, ZY; Sun, DS; Yu, JM; Zhang, JD, 2012)
"Sixty-eight patients with metastatic rectal cancer were enrolled and analyzed."1.38The effect of postoperative pelvic irradiation after complete resection of metastatic rectal cancer. ( Chang, CY; Cho, YB; Choi, DH; Chun, HK; Kim, HC; Lee, WY; Park, HC; Park, JO; Park, YS; Yun, SH, 2012)
"High TS, DPD, and positive lymph node metastasis (pN) were significantly poorer prognostic factors for DFS (TS: P < 0."1.38TS and DPD mRNA levels on formalin-fixed paraffin-embedded specimens as predictors for distant recurrence of rectal cancer treated with preoperative chemoradiotherapy. ( Inoue, Y; Kobayashi, M; Koike, Y; Kusunoki, M; Miki, C; Okugawa, Y; Saigusa, S; Tanaka, K; Toiyama, Y; Yokoe, T, 2012)
"We obtained total RNA from residual cancer cells using microdissection from a total of 52 rectal cancer specimens from patients who underwent preoperative CRT."1.38Prognostic significance of glucose transporter-1 (GLUT1) gene expression in rectal cancer after preoperative chemoradiotherapy. ( Fujikawa, H; Inoue, Y; Kusunoki, M; Matsushita, K; Okugawa, Y; Saigusa, S; Tanaka, K; Toiyama, Y; Uchida, K, 2012)
" Adverse effects ≥ grade 2 were observed in 32% of the patients and adverse effects ≥ grade 3 in 15%."1.38Safety and outcome of chemoradiotherapy in elderly patients with rectal cancer: results from two French tertiary centres. ( Bensadoun, RJ; Hamidou, H; Michel, P; Paillot, B; Roullet, B; Silvain, C; Tougeron, D; Tourani, JM, 2012)
"A total of 38 T3-4/N+ rectal cancer patients received capecitabine-oxaliplatin and radiotherapy followed by surgery."1.38A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. ( Carlomagno, C; D'Incalci, M; De Placido, S; De Stefano, A; Della Vittoria Scarpati, G; Falcetta, F; Marchini, S; Pepe, S; Singh, VK; Ubezio, P, 2012)
"After nCRT for rectal cancer, postsurgery CEA level may have more prognostic value than pretreatment level."1.38Combined modality therapy for rectal cancer: the relative value of posttreatment versus pretreatment CEA as a prognostic marker for disease recurrence. ( Chang, DT; Hong, JC; Koong, AC; Liauw, SL; McDonnell, SE; Minsky, BD; Song, S, 2012)
"The patient was a 60-year-old man with cancer of the rectum, with huge multiple hepatic metastases."1.38[Huge unresectable multiple hepatic metastases of rectum cancer responding to combined therapy with FOLFIRI +bevacizumab - a case report]. ( Bando, Y; Katakawa, M; Ogata, S; Tagami, Y, 2012)
"In spite of advances in rectal cancer surgery and the use of preoperative 5-fluorouracil-(5-FU) based chemoradiotherapy (CRT) in stage II and III disease distant metastases still occur in about 35-40% of the patients."1.38Intensified neoadjuvant chemoradiotherapy in locally advanced rectal cancer -- impact on long-term quality of life. ( Brade, J; Gencer, D; Hofheinz, RD; Hofmann, WK; Horisberger, K; Kienle, P; Kripp, M; Post, S; Welzel, G; Wenz, F; Wieneke, J, 2012)
"An analysis of 162 rectal cancer patients who underwent curative surgery between 2005 and 2010."1.38Lymph node retrieval after preoperative chemoradiotherapy for rectal cancer. ( Contu, PC; Damin, DC; Ferreira, PR; Kliemann, LM; Rosito, MA; Schwartsmann, G; Tarta, C, 2012)
"Nine cases with highly advanced rectal cancer for which curative surgery was potentially difficult were enrolled(clinical T4 in 7 cases, lateral node metastasis in 3 cases, M1 in 2 cases)."1.38[Evaluation of modified OPTIMOX1 plus bevacizumab as the neoadjuvant therapy for highly advanced rectal cancers]. ( Adachi, K; Hirano, A; Imai, K; Koda, K; Kosugi, C; Nakagawa, R; Shiragami, R; Suzuki, M; Tezuka, T; Yamazaki, M; Yasuda, H, 2012)
"After matching, only CEA and metastasectomy, but not CCRT, were independent prognostic factors."1.38Concurrent chemoradiotherapy followed by metastasectomy converts to survival benefit in stage IV rectum cancer. ( Chang, SC; Chen, WS; Jiang, JK; Lan, YT; Lee, LK; Lin, CC; Lin, JK; Lin, TC; Liu, JH; Teng, HW; Tzeng, CH; Wang, HS; Yang, SH; Yen, CC, 2012)
"Standard treatment for locally advanced rectal cancer (cT3/4 and/or cN+) includes neoadjuvant chemoradiotherapy with fluoropyrimidines (capecitabine or 5-fluorouracil) followed by radical surgical resection."1.38MicroRNA expression profile associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients. ( Fabian, P; Gombosova, J; Kocakova, I; Nekvindova, J; Radova, L; Sana, J; Slaby, O; Svoboda, M; Vyzula, R, 2012)
"Following diagnosis of T4 rectal cancer, preoperative chemotherapy was initiated with the aim of downstaging the tumor and avoiding total pelvic exenteration."1.38[Complete response obtained by preoperative chemotherapy in a case of T4 rectal cancer]. ( Akasaka, H; Hakamada, K; Koyama, M; Morohashi, H; Murata, A; Sakamoto, Y; Yokoyama, H, 2012)
"An approximately 50-year-old man with rectal cancer(RbP)[ cT3(cA), cN3, cM0, and cStage IIIb] who desired anus preservation was administered mFOLFOX6 therapy."1.38[A case of advanced rectal cancer treated effectively with intersphincteric resection and preoperative chemotherapy]. ( Ito, Y; Kimura, A; Kubo, N; Kudo, Y; Kurushima, M; Morita, T; Nishikawa, S; Takahashi, K; Tokura, T; Umehara, Y; Yachi, T, 2012)
"Sixteen months after the diagnosis of rectal cancer, the patient died."1.38[A case of advanced rectal cancer with lung and bone metastasis that was successfully treated with mFOLFOX6+bevacizumab]. ( Higuchi, T; Iida, S; Ishiguro, M; Ishikawa, T; Kobayashi, H; Masuda, T; Matsuyama, T; Okazaki, S; Sugihara, K; Uetake, H; Yamauchi, S, 2012)
" This case demonstrates the successful treatment and CR of recurrent lung metastasis after surgery for rectal cancer using lung RFA therapy and long-term administration of FOLFIRI."1.38[A case report of recurrent lung metastasis after surgery for rectal cancer for which lung radiofrequency ablation therapy and long-term administration of FOLFIRI were effective]. ( Fukushima, M; Hoshino, M; Murakami, M; Naruse, H; Suzuki, N; Suzuki, S; Tominaga, K, 2012)
"A total of 238 rectal cancer patients treated in a neo-adjuvant setting by a fluoropyrimidines-based chemo-radiotherapy (RT) were genotyped for 25 genetic polymorphisms in 16 genes relevant for treatment-associated pathways."1.37Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy. ( Agostini, M; Biason, P; Canzonieri, V; Cecchin, E; De Mattia, E; De Paoli, A; Friso, ML; Nitti, D; Pucciarelli, S; Sigon, R; Toffoli, G; Visentin, M, 2011)
"Forty-four patients with rectal cancer treated with 5-FU-based preoperative CRT were prospectively enrolled in this study."1.37Thymidylate synthase gene polymorphism affects the response to preoperative 5-fluorouracil chemoradiation therapy in patients with rectal cancer. ( Choi, J; Choi, SH; Hur, H; Kang, J; Keum, KC; Kim, H; Kim, NK; Lee, KY; Lee, MY; Min, BS; Shin, SJ, 2011)
"Stage II or III rectal cancer patients were evaluated and treated with RT and 5-FU preoperatively (neoadjuvant treatment, NG) or after surgical resection of the cancer (adjuvant treatment, AG)."1.37Imunoexpression of Ki-67 and p53 in rectal cancer tissue after treatment with neoadjuvant chemoradiation. ( Andrade, NR; Forones, NM; Gomes, TS; Neto, RA; Oshima, CT, 2011)
"Patients with rectal cancer, candidates to receive pCRT, were enrolled in a multicenter prospective observational trial."1.37Patient-reported outcomes after neoadjuvant chemoradiotherapy for rectal cancer: a multicenter prospective observational study. ( Amato, A; Capirci, C; Cuicchi, D; De Paoli, A; Del Bianco, P; Efficace, F; Nitti, D; Pucciarelli, S; Serpentini, S, 2011)
"Patients with locally advanced rectal cancer treated with neoadjuvant therapy can safely undergo laparoscopic proctectomy with a low rate of complications."1.37Laparoscopic proctectomy after neoadjuvant therapy: safety and long-term follow-up. ( Cone, MM; Diggs, BS; Herzig, DO; Lu, KC; Oommen, SC; Rea, JD, 2011)
"Adjuvant chemotherapy in rectal cancer is not well defined."1.37Risk-adapted adjuvant chemotherapy after concomitant fluoropyrimidine-radiotherapy neoadjuvant treatment for patients with resectable cT3-4 or N+ rectal cancer. ( Alfonso, R; Corona, J; Custodio, A; de las Heras, M; Dıaz-Rubio, E; Ortega, L; Puente, J; Rodriguez, L; Sanchez, JC; Sastre, J, 2011)
"Capecitabine is an attractive radiosensitizer."1.37Toxicity and complications of preoperative chemoradiotherapy for locally advanced rectal cancer. ( Cats, A; Gerhards, MF; Heuff, G; Marijnen, CA; Swellengrebel, HA; van Geloven, AA; van Tets, WF; Verheij, M; Verwaal, VJ; Vincent, A, 2011)
"Patients with mucinous rectal cancer experienced a lower rate of T-downstaging after PCRT and had a poorer prognosis than did patients with nonmucinous cancer."1.37Mucinous rectal cancer: effectiveness of preoperative chemoradiotherapy and prognosis. ( Kim, CW; Kim, JC; Kim, JH; Kim, TW; Lim, SB; Shin, US; Yoon, SN; Yoon, YS; Yu, CS, 2011)
"In 10-24% of patients with rectal cancer who are treated with neoadjuvant chemoradiation, no residual tumor is found after surgery (ypT0)."1.37Diffusion-weighted MRI for selection of complete responders after chemoradiation for locally advanced rectal cancer: a multicenter study. ( Bakers, FC; Barbaro, B; Beets, GL; Beets-Tan, RG; Haustermans, K; Lambrecht, M; Lambregts, DM; Maas, M; Valentini, V; Vandecaveye, V, 2011)
"Seventeen patients with Stage II or III rectal cancer had a planning CT scan with rectal contrast before commencement of preoperative chemoradiation."1.37Rectal motion in patients receiving preoperative radiotherapy for carcinoma of the rectum. ( Bayley, A; Brierley, JD; Brock, KK; Craig, T; Cummings, B; Dawson, LA; Dinniwell, R; Kim, JJ; Moseley, JL; Ringash, J; Sampson, E; Scott, S; Wong, R, 2011)
"We retrospectively evaluated 333 rectal cancer patients who received preoperative CRT followed by surgery with curative intent between January 2000 and December 2006."1.37Clinical significance of pre- to post-chemoradiotherapy s-CEA reduction ratio in rectal cancer patients treated with preoperative chemoradiotherapy and curative resection. ( Kim, CW; Kim, JC; Kim, KH; Lim, SB; Yang, SS; Yoon, SN; Yoon, YS; Yu, CS, 2011)
"Patients with locally advanced rectal cancer (cUICC stages II/III) are typically treated with preoperative 5-fluorouracil-based (5-FU-based) radiochemotherapy (RCT)."1.37Gender-specific acute organ toxicity during intensified preoperative radiochemotherapy for rectal cancer. ( Becker, H; Beissbarth, T; Christiansen, H; Conradi, LC; Hennies, S; Hess, CF; Liersch, T; Rave-Fränk, M; Schirmer, M; Sprenger, T; Wolff, HA, 2011)
"A 50-year-old man with advanced rectal cancer and multiple liver metastases experienced DIC during third-line treatment with cetuximab plus irinotecan, following 5-fluorouracil, leucovorin, oxaliplatin (FOLFOX) plus bevacizumab and 5-fluorouracil, leucovorin, and irinotecan (FOLFIRI) plus bevacizumab."1.37A case of heavily pretreated rectal cancer with disseminated intravascular coagulation that improved following reintroduction of FOLFOX plus bevacizumab. ( Kondo, C; Mizota, A; Muro, K; Nomura, M; Shitara, K; Takahari, D; Ura, T; Yokota, T, 2011)
"Ninety-six patients with rectal cancer received neoadjuvant therapy (41 were treated with radiotherapy and 55 with chemoradiotherapy) before surgery."1.37Combination of differentiation and T stage can predict unresponsiveness to neoadjuvant therapy for rectal cancer. ( Lin, GL; Qiu, HZ; Wu, B; Xiao, Y, 2011)
"It is said that disseminated carcinomatosis of the bone marrow has a poor prognosis, but we were able to obtain a good response in this case by chemotherapy."1.37[Successful chemotherapy of carcinomatosis of the bone marrow with disseminated intravascular coagulation from a rectal carcinoma found by eosinophilia]. ( Abiko, S; Gotoh, J; Higashiyama, A; Kawamura, A; Kawamura, N; Kudo, M; Meguro, J; Nagasako, T; Takano, M; Tamaki, T; Tanino, M; Yamamoto, Y; Yonekawa, M, 2011)
"A detailed examination revealed a rectal cancer with metastasis to the right ovary."1.37[A case of advanced rectal cancer resected successfully after preoperative XELOX chemotherapy]. ( Hatakeyama, K; Iiai, T; Kameyama, H; Nogami, H; Saitou, K; Umezu, H; Yagi, Y, 2011)
"The finding that some rectal cancers respond to neoadjuvant chemoradiation is broadening new surgical options for the treatment of some of these tumors that, until now, required a total mesorectal excision."1.37Accuracy of endoscopic ultrasound to assess tumor response after neoadjuvant treatment in rectal cancer: can we trust the findings? ( Arbea, L; Aristu, J; Baixauli, J; Beorlegui, C; Hernandez-Lizoain, JL; Pastor, C; Sola, J; Subtil, JC, 2011)
"Seven patients with rectal cancers which were difficult to ensure surgical margins for because of huge tumors(over 60mm in diameter), invasion to other organs, or severe nodal metastases, were treated with preoperative chemotherapy consisting of 2-10 courses of mFOLFOX6."1.37[Pilot study of preoperative mFOLFOX6 chemotherapy for advanced rectal cancers which were difficult to ensure surgical margins]. ( Fuyuhiro, Y; Hirakawa, K; Inoue, T; Kashiwagi, S; Maeda, K; Nagahara, H; Nakamoto, K; Noda, E, 2011)
"For patients with locally advanced rectal cancer (LARC) neoadjuvant chemoradiotherapy is recommended as standard therapy."1.37Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy. ( Bohn, B; Erben, P; Gencer, D; Hofheinz, RD; Hofmann, WK; Horisberger, K; Kähler, G; Kienle, P; Post, S; Schwaab, J; Ströbel, P; Wenz, F, 2011)
"He was diagnosed as advanced rectal cancer with an invasion of prostate, and we conducted neoadjuvant capecitabine, oxaliplatin, bevacizumab and radiation therapy."1.37[A resected case of locally invasive rectal cancer successfully treated with neoadjuvant capecitabine, oxaliplatin, bevacizumab and radiation therapy]. ( Arima, N; Shigaki, N; Sugita, H; Suzuki, S; Yamashita, H; Yokoyama, S, 2011)
"BACKGROUND Survival in rectal cancer remains unchanged despite improved treatment modalities."1.37Molecular changes consistent with increased proliferation and invasion are common in rectal cancer. ( Beynon, J; Hughes, R; Jenkins, G; Parry, J, 2011)
"Its prognostic value in rectal cancer is somewhat unknown."1.37Securin identifies a subgroup of patients with poor outcome in rectal cancer treated with long-course (chemo)radiotherapy. ( Avoranta, ST; Korkeila, EA; Minn, HR; Pyrhönen, SO; Sundström, JT; Syrjänen, KJ, 2011)
"FOLFIRI was effective for recurrent rectal cancer with paraaortic LN metastasis."1.37[A case of recurrent rectal cancer with paraaortic lymph node metastasis treated by FOLFIRI therapy leading to complete response]. ( Nishimura, Y; Sakamoto, H; Tanaka, Y; Yamaguchi, K; Yatsuoka, T, 2011)
"Two years later, he was diagnosed for rectal cancer and bilateral lung metastases by TBLB."1.37[A case of colon cancer with long-term survival treated by resection of recurrence on the rectum and chemotherapy for lung metastasis]. ( Amagasa, H; Ami, K; Ando, M; Arai, K; Fukuda, A; Ganno, H; Kurokawa, T; Nagahama, T; Nakamura, M; Okada, Y; Tei, S; Watayo, Y, 2011)
"Local postoperative complications affected 25 of 61 patients, who had lower perioperative neutrophil increases than their counterparts (P = 0."1.36Suppression of the postoperative neutrophil leucocytosis following neoadjuvant chemoradiotherapy for rectal cancer and implications for surgical morbidity. ( Glynne-Jones, R; Kerr, SF; Klonizakis, M, 2010)
"Pelvic recurrent rectal cancer is still a challenging clinical problem, and patients generally have a dismal prognosis and a poor quality of life."1.36Locally recurrent rectal cancer: prognostic factors and long-term outcomes of multimodal therapy. ( Bossola, M; Doglietto, GB; Pacelli, F; Papa, V; Rosa, F; Sanchez, AM; Tortorelli, AP; Valentini, V, 2010)
"Capecitabine was administrated 1,650 mg/m(2)/day, 7 days/week."1.36Thymidine phosphorylase to dihydropyrimidine dehydrogenase ratio as a predictive factor of response to preoperative chemoradiation with capecitabine in patients with advanced rectal cancer. ( Aygerinos, K; Baltatzis, G; Bamias, A; Beroukas, K; Boskos, CS; Dimopoulos, MA; Korkolis, D; Lamproglou, I; Liacos, C; Papasavvas, P; Stoupa, E; Terpos, E, 2010)
"Rectal tumors were localized within 12 cm from the anocutaneous verge."1.36Neoadjuvant chemoradiotherapy with capecitabine followed by laparoscopic resection in locally advanced tumors of middle and low rectum - toxicity and complications of the treatment. ( Bartos, J; Czudek, S; Gruna, J; Kycina, R; Parvez, J; Skrovina, M; Soumarova, R; Wendrinski, A, 2010)
"Of 100 patients with locally advanced rectal cancer, 32 were clinically staged as T3N0M0."1.36Clinically-staged T3N0 rectal cancer: is preoperative chemoradiotherapy the optimal treatment? ( Ceccarelli, C; Cola, B; Cuicchi, D; Di Fabio, F; Di Tullio, P; Iacopino, B; Lecce, F; Lombardi, R; Martoni, A; Minni, F; Neri, S; Pini, S; Pinto, C; Taffurelli, M; Tardio, ML; Ugolini, G, 2010)
"Colonoscopy detected rectal cancer and sigmoid al polyps."1.36[A case of advanced rectal cancer with liver and lung metastasis showing a complete response by neo-adjuvant FOLFOX4 chemotherapy]. ( Baba, K; Ishigami, S; Kitazono, M; Matsushita, D; Natsugoe, S; Ogawa, H; Shinchi, H; Ueno, S, 2010)
"Fourty-six rectal cancer patients, 25 RCT- and 21 RT-patients, were included in this study."1.36Evaluation of early metabolic responses in rectal cancer during combined radiochemotherapy or radiotherapy alone: sequential FDG-PET-CT findings. ( Buijsen, J; de Ruysscher, D; Janssen, MH; Lambin, P; Lammering, G; Ollers, MC; van den Bogaard, J; van Stiphout, RG, 2010)
"Pre-operative chemoradiation in low rectal cancer is not associated with a higher incidence of peri-operative complications and its benefits may include reduction local recurrence."1.36Impact of neoadjuvant treatment on total mesorectal excision for ultra-low rectal cancers. ( Fan, JF; Law, WL; Lim, YK; Liu, R; Lo, OS; Poon, JT, 2010)
"She was diagnosed to have rectal cancer."1.36[Elderly patient with recurrent rectal cancer successfully responded to modified FOLFOX6 chemotherapy with bevacizumab--a case report]. ( Adachi, E; Hattori, M; Kato, N; Kawase, Y; Kuroiwa, M; Matsushita, H; Mizuno, A; Okochi, O; Sato, Y; Takami, Y; Takeda, S; Tsuboi, K, 2010)
"2 Gy/f, 2 f/d plus concurrent capecitabine at an oral dosage of 825 mg/m2 bid on each day of radiotherapy period."1.36[Efficacy observation of accelerated hyperfractionation recourse radiotherapy plus concurrent capecitabine in the treatment of locoregional recurrent rectal cancer]. ( Dai, Y; Shao, ZY; Yu, JM; Zhang, JD, 2010)
"CASE 2: A 67-year-old male with colon cancer and liver and lung metastases was referred to our Dept."1.36[Two cases of unstable angina in patients treated with bevacizumab]. ( Okada, Y; Okura, Y; Takii, Y, 2010)
"Tumor response of rectal cancer to preoperative chemoradiotherapy (CRT) varies considerably."1.36Prediction of response to preoperative chemoradiotherapy in rectal cancer by multiplex kinase activity profiling. ( Boender, PJ; de Wijn, R; Dueland, S; Flatmark, K; Folkvord, S; Giercksky, KE; Grøholt, KK; Hole, KH; Johansen, M; Nesland, JM; Ree, AH; Ruijtenbeek, R, 2010)
"Twenty men with primary rectal cancer clinically involving the lower urinary tract organs underwent extended colorectal resection combined with radical prostatectomy."1.36Preliminary experience with bladder preservation for lower rectal cancers involving the lower urinary tract. ( Ito, M; Kobayashi, A; Minagawa, N; Nishizawa, Y; Saito, N; Sugito, M; Suzuki, T; Tanaka, T; Watanabe, K, 2010)
"We report two cases of colorectal cancer whose serum iron level demonstrated recurrent elevation after chemotherapy."1.36[Two cases of colorectal cancer presenting with periodic, transient elevation of serum iron due to hemolysis after chemotherapy including 5-FU]. ( Furuse, J; Hosokawa, Y; Itabashi, M; Iwamoto, N; Kase, Y; Kitagawa, N; Miyazawa, T; Motoori, S; Saisho, H, 2010)
"Most colorectal cancer patients with liver metastases are not resectable upon initial diagnosis."1.36[Successful treatment with cetuximab combination chemotherapy in a case of FOLFOX-refractory rectal cancer with previously unresectable multiple liver metastases leading to complete resection]. ( Chin, K; Fujimoto, Y; Hatake, K; Ichimura, T; Matsusaka, S; Mitsuhashi, K; Mizunuma, N; Ogura, M; Ozaka, M; Saiura, A; Shinozaki, E; Suenaga, M; Yamamoto, N, 2010)
"Patients with nonmetastatic distal rectal cancer treated by neoadjuvant chemoradiation therapy, including 50."1.36Complete clinical response after neoadjuvant chemoradiation therapy for distal rectal cancer: characterization of clinical and endoscopic findings for standardization. ( Gama-Rodrigues, J; Habr-Gama, A; Kessler, H; Marks, J; Perez, RO; Wynn, G, 2010)
"We report two cases of venous thrombosis confirmed during the bevacizumab combination chemotherapy for colorectal cancer."1.36[Two cases of venous thrombosis confirmed during the bevacizumab combination chemotherapy for colorectal cancer]. ( Hosokawa, T; Iwao, Y; Koshiishi, H; Koshinaga, T; Matsuyama, T; Nishida, K; Okamura, T; Sakamoto, K; Tokita, H, 2010)
"The patient was diagnosed as idiopathic thrombocytopenic purpura (ITP) by several examinations but medical control including steroids failed."1.36[Idiopathic thrombocytopenic purpura during chemotherapy for liver metastasis of rectal cancer]. ( Ebisui, C; Ide, Y; Kinuta, M; Mikami, K; Momozane, T; Mukai, R; Murakami, M; Murata, K; Nagase, H; Nishigaki, T; Okada, K; Owada, Y; Yamada, M; Yanagisawa, T; Yokouchi, H, 2010)
"A 42-year-old man with advanced rectal cancer underwent a low anterior resection with TME and pelvic lateral lymph-node and paraaortic lymph-node dissections."1.36[A long-term disease-free survival case of advanced rectal cancer with massive metastasis to the lateral pelvic and para-aortic lymph nodes]. ( Gotoh, K; Ishikawa, O; Kano, S; Kishi, K; Miyashiro, I; Motoori, M; Noura, S; Ohigashi, H; Ohue, M; Shingai, T; Takahashi, H; Yamada, T; Yano, M, 2010)
"A colonoscopy revealed primary rectal cancer."1.36[A case of successfully treated lower rectal cancer with both inguinal lymph nodes by chemoradiotherapy]. ( Danno, K; Imaoka, S; Inatome, J; Kagara, N; Kanoh, T; Kim, C; Kimura, Y; Monden, T; Nakamura, H; Nakano, Y; Ohnishi, T; Taniguchi, H; Tono, T; Tsukao, Y; Watanabe, A, 2010)
"Colonoscopy detected an advanced rectal cancer."1.36[A case report of advanced rectal cancer showing a pathological complete response by neo-adjuvant FOLFOX chemotherapy]. ( Hirakawa, K; Inoue, T; Kubo, N; Maeda, K; Muguruma, K; Murata, A; Nagahara, H; Noda, E; Ohira, M; Tanaka, H; Yamada, N, 2010)
"We report here a case of rectal cancer with synchronous multiple liver metastases successfully treated with a combined chemotherapy of modified FOLFOX6 (mFOLFOX6) and bevacizumab."1.36[A case of rectal cancer with synchronous multiple liver metastases successfully treated with combined chemotherapy of modified FOLFOX6 and bevacizumab]. ( Andou, S; Kitamura, Y; Tokunou, K; Toshimitsu, H; Tsushimi, K; Yamamoto, T, 2010)
"Local therapy for early rectal cancer is a valid alternative to the classical radical operation, which has a higher morbidity and mortality rate."1.35Transanal endoscopic microsurgery for the treatment of selected patients with distal rectal cancer: 15 years experience. ( Baldarelli, M; Bartolacci, S; Grillo Ruggeri, F; Guerrieri, M; Lezoche, E; Mantello, G; Organetti, L, 2008)
"However, G-CSF-producing colorectal cancer (CRC) has never been reported in the English literature."1.35Granulocyte-colony stimulating factor producing rectal cancer. ( Akamo, Y; Funahashi, H; Ochi, N; Sakamoto, M; Satoh, M; Sawai, H; Takahashi, H; Takayama, S; Takeyama, H; Wakasugi, T; Yasuda, A, 2008)
"Tumor biopsies from 35 patients with rectal cancer before therapy and parallel tumor biopsies from 31 patients two weeks after starting preoperative capecitabine chemoradiotherapy were taken."1.35Micro-RNAs miR125b and miR137 are frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer. ( Dvorak, J; Izakovicova Holla, L; Kocakova, I; Sefr, R; Svoboda, M; Tichy, B; Vrtkova, I, 2008)
"Locally advanced rectal cancer is frequently treated with neoadjuvant chemoradiotherapy to reduce local recurrence and possibly improve survival."1.35A simplified tumor regression grade correlates with survival in locally advanced rectal carcinoma treated with neoadjuvant chemoradiotherapy. ( Armstrong, J; Beddy, D; Fennelly, D; Gibbons, D; Hyland, JM; Lim, C; Moriarty, M; Sheahan, K; White, A; Winter, DC, 2008)
"We report a 59-year-old woman with rectal cancer who underwent low anterior resection in March 2007."1.35[A case with liver resection of metastasis from rectal cancer after FOLFOX4+bevacizumab treatment]. ( Fujimitsu, Y; Kojima, H; Kojima, T; Kure, N; Matsui, T; Uemura, T, 2008)
"Interstitial pneumonia was suspected, and we started treatment with steroid medication, but this had no effect."1.35[A case of diffusely infiltrating rectal cancer with pulmonary lymphangitis carcinomatosa successfully treated with mFOLFOX6 chemotherapy as salvage]. ( Fujita, M; Ishikawa, M; Katano, K; Mizuno, A; Okada, Y; Yamagishi, Y, 2008)
"In total, 106 patients with cT3,4 rectal cancer who received preoperative radiotherapy alone or concurrently with capecitabine chemotherapy at Nottingham City Hospital, UK were studied."1.35Regression of rectal cancer with radiotherapy with or without concurrent capecitabine--optimising the timing of surgical resection. ( Bessell, EM; Dhadda, AS; Zaitoun, AM, 2009)
"Forty-three men with rectal cancer had baseline and postchemoradiation FSH, LH, and testosterone measured."1.35Alterations in hormone levels after adjuvant chemoradiation in male rectal cancer patients. ( Fisher, B; Perera, F; Stitt, L; Yoon, FH, 2009)
"A treatment of 5-fluorouracil, 500 mg/body per day intravenously, or oral UFT-E (300 mg/m2) with l-leucovorin (75 mg) per day, or oral S-1 (80 mg/m2) per day five days a week, was given during radiotherapy."1.35[Our experiences of preoperative chemo-radiotherapy for T4 primary rectal cancer]. ( Agata, T; Aoyama, H; Funahashi, M; Hanai, T; Honda, K; Katsuno, H; Koide, Y; Maeda, K; Matsuoka, H; Noro, T; Sato, H; Shiota, M, 2008)
"He was diagnosed with lower rectal cancer by colonoscopy and referred to our hospital for therapy."1.35[Complete response of advanced rectal cancer with combined therapy of S-1 + chemo-radiation plus FOLFIRI--a case report]. ( Akagi, K; Fujita, J; Hata, T; Hayashi, S; Ikeda, K; Kagawa, Y; Kato, H; Kawanishi, K; Kitada, M; Maeda, S; Nomura, M; Oshima, N; Sasaki, T; Shimano, T; Shimizu, J; Takamoto, K; Tsukahara, Y, 2008)
"Recently, standard therapies for either gastric cancer or colorectal cancer have been established through the development of multidrug systemic chemotherapy and the appearance of molecular targeting drugs."1.35[Hepatic artery infusion chemotherapy to three liver metastasis cases in which systemic chemotherapy was impossible or ineffective]. ( Ando, K; Emi, Y; Endo, K; Kakeji, Y; Maehara, Y; Morita, M; Oki, E; Saeki, H; Sugiyama, M, 2008)
"Serum levels of 5-fluorouracil(5-FU)were measured in a patient receiving pharmacokinetic modulation chemotherapy( PMC), with 5-FU, as well as a combination of oxaliplatin and infusional 5-FU plus leucovorin(FOLFOX)."1.35[Pharmacokinetic monitoring of 5-fluorouracil may improve the clinical benefit with an individualized regimen-a case report]. ( Asakura, T; Hatakeyama, K; Kanda, J; Muneoka, K; Sasaki, M; Shirai, Y; Wakabayashi, H; Wakai, T, 2009)
"We report a CR case of advanced rectal cancer successfully treated with 39 courses of mFOLFOX6."1.35[A CR case of colorectal cancer given 39 courses of FOLFOX]. ( Fujiwara, M; Imai, N; Isaka, T; Kaneko, M; Kobayashi, K; Naota, H; Ogura, S; Otsubo, M; Taniguchi, K, 2009)
"We report here two cases of interstitial lung disease occurring in association with the use of this combination chemotherapy."1.35[Two cases of interstitial lung diseases in patients treated with oxaliplatin, 5-fluorouracil and Leucovorin (FOLFOX)]. ( Kato, S; Miyate, Y; Ogasawara, N; Ohori, H; Suzuki, M; Takahashi, M, 2009)
"Up to 6% of women with colorectal cancer are diagnosed in the reproductive age and are at risk for premature ovarian failure and infertility due to pelvic irradiation and chemotherapy."1.35Fertility preservation for young women with rectal cancer--a combined approach from one referral center. ( Elizur, SE; Huang, JY; Levin, D; Meterissian, S; Tan, SL; Tulandi, T, 2009)
"The patient was diagnosed stageIV rectal cancer and resected primary focus and lymph node metastasis."1.35[A successfully resected case of rectal cancer with liver metastases treated with mFOLFOX6 and bevacizumab]. ( Fujino, Y; Fujita, T; Kanaji, S; Kanbara, Y; Kawasaki, K; Kobayashi, I; Nakamura, T; Ohno, M; Osawa, M; Tsuchida, S; Ueno, K, 2009)
"In patients with locally advanced rectal cancer (LARC) staging and, after preoperative chemo-radiation therapy (CRT), restaging workup could be useful to tailor therapeutic approaches."1.35The role of dual-time combined 18-fluorodeoxyglucose positron emission tomography and computed tomography in the staging and restaging workup of locally advanced rectal cancer, treated with preoperative chemoradiation therapy and radical surgery. ( Banti, E; Bianchini, E; Capirci, C; Crepaldi, G; Del Favero, G; Facci, E; Galeotti, F; Gava, M; Marano, G; Panzavolta, R; Pasini, F; Rampin, L; Rubello, D, 2009)
"Following preoperative treatment of rectal cancer with chemoradiotherapy (CRT), a complete pathological response (CPR) can be seen in the surgical specimen."1.35Complete pathologic response after preoperative rectal cancer chemoradiotherapy. ( Ciccocioppo, A; Hewett, PJ; Rieger, NA; Stephens, JH, 2009)
"A 75-year-old man was diagnosed with gastric cancer (UL post c0- II c (c T1N0) and M-less ctype II (cT2N0)) and rectal cancer (Rb ctype II (cT2N1) with multiple lung metastases (M1)."1.35[A case of advanced gastric and rectal cancer (double cancer) successfully treated with mFOLFOX6 therapy]. ( Furuta, A; Hatsugai, K; Ishibashi, S; Ishii, T; Kaneda, I; Masuoka, H; Ohara, M; Sarashina, H; Sekine, Y; Shoji, M; Watanabe, G, 2009)
"5-Fluorouracil (5-FU) is a chemotherapeutic agent commonly used in a number of solid malignancies, including colorectal cancer."1.35A case of 5-fluorouracil-induced acute psychosis. ( Alabsi, E; Fakih, M; Fora, A, 2009)
"Thirty-three patients with rectal cancer underwent preoperative CRT."1.35Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. ( Ioue, Y; Kusunoki, M; Miki, C; Okugawa, Y; Saigusa, S; Tanaka, K; Toiyama, Y; Yokoe, T, 2009)
" The primary dose of oxaliplatin (L-OHP) ranged from 60 mg/m(2) to 85 mg/m(2), and adverse reactions and serum platinum concentration were monitored."1.35[The pharmacokinetics and safety of oxaliplatin in a hemodialysis patient treated with mFOLFOX6 therapy]. ( Fujita, M; Kataoka, Y; Katayama, T; Koide, T; Matsuda, H; Okuda, M; Yamagishi, Y, 2009)
"Approximately 20% of rectal cancer patients undergoing neoadjuvant chemoradiation achieve pCR, which has been associated with decreased local recurrence and improved recurrence-free survival."1.35Predictive factors of pathologic complete response after neoadjuvant chemoradiation for rectal cancer. ( de Campos-Lobato, LF; Dietz, D; Fazio, VW; Geisler, DP; Kalady, MF; Lavery, IC; Stocchi, L, 2009)
"Forty patients with rectal cancer underwent 5-fluorouracil based chemoradiotherapy followed by curative surgery."1.35Microdissection is essential for gene expression analysis of irradiated rectal cancer tissues. ( Inoue, Y; Kusunoki, M; Miki, C; Saigusa, S; Tanaka, K; Toiyama, Y; Yokoe, T, 2009)
"Prognosis of stage II colorectal cancer varies."1.35[Prognostic analysis of 443 cases of stage II colorectal cancer and the value of adjuvant chemotherapy]. ( Ding, PR; Li, LR; Lin, JZ; Pan, ZZ; Peng, ZH; Wan, DS; Wu, XJ; Zhou, ZG, 2009)
"Patients with locally advanced rectal cancer undergoing preoperative radiotherapy have disparity in pathological tumor regression."1.35[Multivariate analysis of clinicopathologic factors correlated with pathological complete response following preoperative radiotherapy in rectal adenocarcinoma]. ( Ding, PR; Lin, JZ; Pan, ZZ; Wan, DS; Zeng, ZF, 2009)
"Twenty-two specimens of colorectal cancer were collected."1.35[Correlation of chemosensitivity tested using histoculture drug response assay to expression of multidrug resistance genes and proteins in colorectal cancer tissues]. ( Chen, G; Fu, LW; Liang, YJ; Qiu, HB; Yuan, SQ; Zhang, LY; Zhou, ZW, 2009)
"Data concerning the type and stage of rectal cancer, multimodal treatment (surgery with or without neoadjuvant therapy or adjuvant therapy) and treatment according to the level of medical care of hospitals were recorded from 2000 to 2008."1.35[Practical neoadjuvant and adjuvant therapies for rectal cancer. How many patients are actually recruited in multimodality therapy concepts? An analysis of the Tumour Centre Schwerin]. ( Dommisch, K; Sauer, J; Sobolewski, K, 2009)
"A detailed examination revealed a rectal cancer with direct invasion of the primary rectal carcinoma into the prostate."1.35[Two cases of advanced rectal cancer resected successfully after neoadjuvant chemotherapy with FOLFOX regimen]. ( Ikeda, J; Itokawa, Y; Koide, K; Lee, CJ; Shimizu, H; Shioaki, Y; Sonoda, H; Takashina, K; Taniguchi, F; Ueshima, Y; Yamashita, T, 2009)
"A treatment of 5-fluorouracil (500 mg/body) with l-leucovorin (100 mg/body) intravenously once a week, or oral S-1 (100 mg/day/body) for four weeks, was given during radiation therapy."1.35[Assessment of chemoradiation therapy for advanced rectal cancer invaded the pelvic organ]. ( Doi, K; Hirano, Y; Ishihara, A; Kojima, K; Kudo, K; Ochi, T; Ogata, K, 2009)
"A man in his fifties with rectal cancer underwent low anterior resection in another Hospital in January 2006."1.35[A case of liver metastasis of rectal cancer demonstrating complete response for more than two years to mFOLFOX6]. ( Doi, T; Hoshi, M; Iijima, S; Kato, A; Kato, T; Kikkawa, N; Kurokawa, E; Makari, Y; Miyake, Y; Miyo, M; Oshima, S; Sakamoto, T, 2009)
"We report a case of rectal cancer with unresectable multiple liver metastases, which was worried about the transition from liver dysfunction to liver failure."1.35[A case of advanced rectal cancer with severe liver dysfunction due to multiple liver metastases]. ( Enomoto, M; Fujimori, Y; Higuchi, T; Iida, S; Ishiguro, M; Ishikawa, T; Kobayashi, H; Oda, G; Okazaki, S; Sugihara, K; Tsukamoto, S; Uetake, H; Yasuno, M, 2009)
"A 63-year-old female diagnosed as rectal cancer underwent low anterior resection and received adjuvant chemotherapy (folinate/tegafur/uracil therapy)."1.35[A case of surgical approach to the recurrence of the para-aortic lymph nodes after resection of rectal cancer]. ( Endo, W; Fujie, Y; Fukunaga, H; Hojou, S; Kakutani, A; Maeura, Y; Ogino, T; Ota, H; Shimizu, K; Toyoda, Y; Yoshioka, A; Yoshioka, S, 2009)
"Previously irradiated recurrent rectal cancer is a formidable patient threat with limited treatment options."1.35Isolated chemotherapeutic perfusion of pelvis as neoadjuvant or palliative therapy for advanced cancer of the rectum. ( Begossi, G; Belliveau, J; DiSiena, M; Gustafson, E; Wanebo, HJ, 2008)
"Therefore, ERUS-/MRI-staged T3N0 rectal cancer patients should continue to receive preoperative CMT."1.35cT3N0 rectal cancer: potential overtreatment with preoperative chemoradiotherapy is warranted. ( Aristu, JJ; Coco, C; Díaz-González, JA; Guillem, JG; Hernandez-Lizoain, JL; Jeong, SY; Leon, R; Minsky, BD; Nitti, D; Pucciarelli, S; Riedel, ER; Rodriguez-Bigas, MA; Valentini, V; Wong, WD, 2008)
"Sixty patients with locally advanced rectal cancer were treated with preoperative chemoradiation."1.35Preoperative chemoradiation with capecitabine in locally advanced rectal cancer. ( de Bruin, AF; de Wilt, JH; Ferenschild, FT; Nuyttens, JJ; Planting, AS; Verhoef, C, 2008)
"5-fluorouracil was given as continuous infusion 350 mg/m(2)/day five times weekly, and RHT (BSD-2000 system) was applied twice a week within 1 h after radiotherapy."1.35Radiochemotherapy in combination with regional hyperthermia in preirradiated patients with recurrent rectal cancer. ( Buecklein, V; Duehmke, E; Issels, RD; Milani, V; Pazos, M; Rahman, S; Schaffer, M; Schaffer, P; Tschoep, K; Wilkowski, R, 2008)
"The standard adjuvant therapy for rectal cancer is 5-fluorouracil (5-FU) often combined with radiotherapy."1.35A case of 5-fluorouracil-induced peripheral neuropathy. ( De Bleecker, JL; Pauwels, WJ; Werbrouck, BF, 2008)
"The rate of distant metastases increased from 18."1.34Prognostic groups in 1,676 patients with T3 rectal cancer treated without preoperative radiotherapy. ( Eriksen, MT; Haffner, J; Wibe, A; Wiig, JN, 2007)
"In preoperative chemoradiotherapy for rectal cancer, the pathologic response could be improved by administering capecitabine 1 hour before radiotherapy."1.34Optimal time interval between capecitabine intake and radiotherapy in preoperative chemoradiation for locally advanced rectal cancer. ( Ahn, SD; Chang, HM; Choi, EK; Choi, WS; Jang, SJ; Kim, HC; Kim, JC; Kim, JH; Kim, TW; Lee, SW; Ryu, MH; Shin, SS; Yu, CS, 2007)
"19 out of 29 patients were colon cancer, and the other 10 were rectal cancer."1.34[Feasibility of modified FOLFIRI regimen for patients with refractory advanced or recurrent colorectal cancer]. ( Honda, K; Kondo, H; Ohura, K; Sumiyoshi, T; Takahari, D; Tanaka, S; Tsuji, Y; Tsushima, T; Yoshizaki, N, 2007)
"Patients aged > or = 70 years with colon cancer benefit from chemotherapy, with no major added toxicities compared with a younger population."1.34Toxicities and survival among octogenarians and nonagenarians with colorectal cancer treated with chemotherapy or concurrent chemoradiation therapy. ( Fakih, MG; Reddy, N; Yu, J, 2007)
"Resection of locally recurrent rectal cancer (LRRC) after curative resection represents a difficult problem and a surgical challenge."1.34Prognostic and predictive factors after surgical treatment for locally recurrent rectal cancer: a single institute experience. ( Asoglu, O; Emek, E; Igci, A; Kapran, Y; Karanlik, H; Kecer, M; Muslumanoglu, M; Ozmen, V; Parlak, M, 2007)
"Capecitabine is an oral fluoropyrimidine that mimics the pharmaconkinetics of infusional 5-FU."1.34A case of capecitabine-induced coronary microspasm in a patient with rectal cancer. ( Arbea, L; Coma-Canella, I; García-Foncillas, J; Martinez-Monge, R, 2007)
"5-fluorouracil (5FU) has traditionally been the drug of choice in combination with radiation therapy."1.34Phase II study of preoperative irradiation and chemotherapy with capecitabine in patients with locally advanced rectal carcinoma. ( Amichetti, M; Caraul, B; Casula, G; Deidda, MA; Dessì, M; Farci, D; Farigu, R; Lay, GC; Maxia, L; Murtas, R; Orrù, S, 2007)
"He was diagnosed as advanced sigmoid colon cancer which invaded the rectal colon (Ra) and prostate (SI, N 0, P 0, H 0, M (-), cStage IIIa)."1.34[A case of advanced colon cancer invading the rectum effectively treated with chemoradiation therapy before surgery]. ( Maezawa, K; Mizukami, H; Nemoto, H; Sanada, Y; Sasaya, S; Yoshizawa, Y, 2007)
"Grade 3/4 neutropenia was seen in 12 patients (60%), and neuropathy was observed in 11 patients (55%)."1.34Oxaliplatin plus 5-fluorouracil/leucovorin (FOLFOX-4) as salvage chemotherapy in patients with pretreated colorectal cancer. ( Kasai, M; Mitobe, S; Munakata, M; Muto, O; Okada, R; Sakata, Y; Shitara, K, 2007)
"121 locally advanced middle-low rectal cancer patients were treated with preoperative radiotherapy or chemoradiotherapy followed by surgery after rest of 4 to 6 weeks."1.34[Evaluation of preoperative radiotherapy or chemoradiotherapy in sphincter preservation for locally advanced middle-low rectal cancer]. ( Cao, WG; Che, JF; Jin, YN; Li, H; Ma, T; Xi, WQ; Xu, HP; Zhao, R, 2007)
"Radiation enteritis is the main acute side-effect during pelvic irradiation."1.34Dose-volume relationships between enteritis and irradiated bowel volumes during 5-fluorouracil and oxaliplatin based chemoradiotherapy in locally advanced rectal cancer. ( Bendahl, PO; Gunnlaugsson, A; Johnsson, A; Kjellén, E; Nilsson, P; Willner, J, 2007)
"The standard management of rectal cancer continues to be defined by the results of randomized, clinical trials exploring the optimal timing and use of adjuvant chemotherapy and radiation therapy in relation to surgery."1.34Long-term outcomes of patients with localized rectal cancer treated with chemoradiation or radiotherapy alone because of medical inoperability or patient refusal. ( Chao, M; Fong, A; Gibbs, P; Jones, IT; Kipp, D; Lim, L; McLaughlin, S; Millar, JL; Rezo, A; Shapiro, J, 2007)
"Here, we report a case of metastatic rectal cancer showing a complete response (CR) to cycle 4 in FOLFIRI regimen, while maintaining a CR status for over 11 months and good QOL, as a result of chemotherapy with 4 cycles of FOLFIRI followed by UFT."1.34[A case of metastatic rectal cancer showing a sustained complete response to chemotherapy with FOLFIRI followed by UFT]. ( Baba, K; Matsuda, M; Tashima, R; Yamashita, Y; Yokoyama, S, 2007)
"Thirty-nine patients with colorectal cancer, who received m-FOLFOX6 in our institution, were studied."1.34[Efficacy of m-FOLFOX6 therapy for colorectal cancer in elderly patients]. ( Fukunaga, S; Hirakawa, K; Inoue, T; Kaizaki, R; Maeda, K; Nakano, T; Noda, E; Shinto, O; Wada, K; Young Kim, W, 2007)
" The dosage of FOLFOX 4 was reduced after three courses due to neutropenia and diarrhea."1.34[A patient with recurrent rectal cancer in whom pulmonary metastasis disappeared by FOLFOX 4 therapy]. ( Fujisawa, M; Ishibiki, Y; Ishiyama, S; Kitabatake, T; Kojima, K; Machida, M; Nakayama, Y; Nitta, S; Ono, S; Shinjou, K; Urao, M, 2007)
"Twenty-six patients with non-metastatic rectal cancer >T1 on pathologic TNM staging who underwent primary laparoscopic surgery were considered for comparison."1.34Laparoscopic total mesorectal excision after neoadjuvant chemoradiotherapy. ( Bona, S; Elmore, U; Furlan, N; Romario, UF; Rosati, R, 2007)
"We report two cases of advanced low rectal cancer, with preoperative chemo-radiation therapy leading to a complete histological response."1.34[Two cases of advanced low rectal cancer, preoperative chemo-radiation therapy leading to complete histological response]. ( Fujita, H; Jida, M; Kubo, M; Maeda, H; Mizuta, M; Shirakawa, K; Sogabe, O; Udaka, T; Waki, N, 2007)
"A 59-year-old man who had rectal cancer, multiple liver metastases and para-aortic LN metastasis underwent a laparoscopic rectal anterior resection."1.34[A case of multiple liver metastases from rectal cancer in poor performance status successfully treated with hepatic arterial infusion chemotherapy plus CPT-11]. ( Ide, Y; Kinuta, M; Maruyama, K; Murata, K; Ohta, H; Okada, K; Yasumoto, T; Yokouchi, H, 2007)
"In contrast, locally advanced rectal cancers in cUICC-II/-III stages (T3/T4 or N(+)) should receive long-term, 5-FU-based, neoadjuvant chemoradiotherapy according to the excellent results of the CAO/AIO/ARO-94 trial of the German Rectal Cancer Study Group."1.33[Present treatment strategies for rectal carcinoma]. ( Becker, H; Ghadimi, BM; Langer, C; Liersch, T, 2005)
" 5-FU serum concentrations were higher at night time and the peak concentration of 5-FU was obtained at 3 a."1.33[Pharmacokinetic modulating chemotherapy for rectal carcinoma metastases to the liver and lung--a case report]. ( Hatakeyama, K; Muneoka, K; Shirai, Y; Wakai, T; Yokoyama, N, 2005)
"Patients with rectal cancer treated by preoperative chemoradiation showed a surprisingly low rate of micrometastasis detection (7%), even in high-risk patients (T3 and T4 tumors)."1.33Lymph node micrometastasis in stage II distal rectal cancer following neoadjuvant chemoradiation therapy. ( Coelho Siqueira, SA; Gama-Rodrigues, JJ; Habr-Gama, A; Kiss, DR; Nishida Arazawa, ST; Perez, RO; Rawet, V, 2005)
" This study was to explore relationship of DPD to serum concentration of 5-FU in colorectal cancer patients treated with FOLFOX6 regimen, and their correlation to treatment response and adverse events."1.33[Relationship of serum level of dihydropyrimidine dehydrogenase and serum concentration of 5-fluorouracil to treatment response and adverse events in colorectal cancer patients]. ( Dong, QM; He, YJ; Li, S; Li, YY; Xia, ZJ; Zhang, L; Zhou, ZM; Zhou, ZW, 2005)
"Complete response (no residual tumour, TRG 1) was seen in 7% of the patients (3/44) and total or major regression (TRG 1-3) in 73% of the patients (32/44) treated with 50-Gy chemoradiation."1.33Tumour regression grading in the evaluation of tumour response after different preoperative radiotherapy treatments for rectal carcinoma. ( Jantunen, I; Juhola, M; Kairaluoma, M; Kellokumpu, I; Vironen, J, 2005)
"The adjuvant treatment of rectal cancer is a rapidly evolving field."1.33Preoperative chemotherapy and radiotherapy for locally advanced rectal cancer. ( Chao, M; Cullinan, M; Faragher, I; Gibbs, P; Jones, I; McLaughlin, S; Skinner, I; Tjandra, J, 2005)
" These data suggest that 5-FU/l-LV can be given in the outpatient and yields improved prognosis and minimal adverse reactions even in patients in reduced dose or prolonged interval."1.33[Retrospective analysis on efficacy and toxicity of 5-fluorouracil (5-FU) and l-leucovorin (l-LV) in advanced or recurrent colorectal cancer]. ( Chiba, N; Ishioka, C; Kakudo, Y; Kato, S; Ohori, H; Otsuka, K; Sakayori, M; Shibata, H; Takahashi, M; Takahashi, S; Yamaura, G; Yasuda, K; Yoshioka, T, 2005)
"Intersphincteric resection of low rectal tumors is a surgical technique extending rectal resection into the intersphincteric space."1.33Technique and long-term results of intersphincteric resection for low rectal cancer. ( Feil, W; Hölbling, N; Holzer, B; Novi, G; Renner, K; Rosen, HR; Schiessel, R; Urban, M, 2005)
"We tested the hypothesis that rectal tumors are most responsive to neoadjuvant therapy if they possess p53 and/or caspase 8 activity."1.33Tumor response to neoadjuvant chemoradiation therapy for rectal adenocarcinoma is mediated by p53-dependent and caspase 8-dependent apoptotic pathways. ( Coppola, D; Kelley, ST; Marcet, J; Yeatman, T, 2005)
"Patients with a locally advanced rectal cancer, treated by pre-operative CRT were studied."1.33Response to neoadjuvant therapy for rectal cancer: influence on long-term results. ( Arriola, E; Biondo, S; Cambray, M; Del Rio, C; Marti-Rague, J; Navarro, M; Novell, V; Pares, D, 2005)
"In locally advanced rectal cancer, neoadjuvant 5-fluorouracil (5-FU)-based long-term chemoradiotherapy leads to marked tumor reduction and decrease of local recurrence rate."1.33Immunohistochemical analysis of thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase in rectal cancer (cUICC II/III): correlation with histopathologic tumor regression after 5-fluorouracil-based long-term neoadjuvant chemorad ( Aust, DE; Baretton, GB; Becker, H; Häusler, P; Jakob, C; Liersch, T; Meyer, W; Schwabe, W, 2005)
"To investigate the effect and feasibility of concurrent radiation and chemotherapy combined with endorectal brachytherapy in T3 rectal cancer with complete pathologic remission as end point."1.33Preoperative chemoradiation of locally advanced T3 rectal cancer combined with an endorectal boost. ( Bisgaard, C; Hansen, JW; Jakobsen, A; Lindebjerg, J; Mortensen, JP; Rafaelsen, SR, 2006)
"Patients who had rectal cancer with a distal margin within 6 cm of the anal verge had the anus included in the field of radiotherapy (Group A, n = 26)."1.33Preoperative chemoradiation for rectal cancer causes prolonged pudendal nerve terminal motor latency. ( Chao, MW; Gibbs, P; Hiscock, R; Lim, JF; Tjandra, JJ, 2006)
" A decrease of dosage or abundance of continuation was done during the course due to complications."1.33[Five cases of locally advanced rectal cancer or local recurrence performed intra-arterial infusion chemotherapy via the internal iliac artery]. ( Agata, T; Aoyama, H; Funabashi, M; Hanai, T; Kamano, T; Katsuno, H; Koide, Y; Maeda, K; Masumori, K; Noro, T; Sato, H, 2005)
"Twenty pretreatment biopsy samples from rectal cancer patients and their paired, post-CRT surgical specimens (n = 17) were analyzed."1.33Cyclooxygenase-2 (COX-2) levels before and after chemotherapy: a study in rectal cancer. ( El-Hajjar, D; Geradts, J; Groth, J; Iyer, R; Javle, M; Lawrence, D; Watwe, V, 2005)
"In 31 patients with a rectal cancer, tumor biopsies were performed before and after pre-operative venous administration of 4 mg/m2, 6 mg/m2, or 10 mg/m2 of MMC."1.33Upregulation of thymidine phosphorylase in rectal cancer tissues by mitomycin C. ( Fukumitsu, T; Ishibashi, N; Matono, K; Mizobe, T; Ogata, Y; Sasatomi, T; Shirouzu, K; Torigoe, S; Yamashita, N; Yanagawa, T, 2006)
"Patients with bilobar colorectal cancer metastases to the liver present a unique problem in terms of resection."1.33Novel two-step resection for lesions between the middle hepatic vein and vena cava which allows the middle hepatic vein to be preserved. ( Chaudhury, PK; Horton, PJ; Martinie, JB; Metrakos, P; Rochon, C; Tzimas, GN; Znajda, TL, 2006)
"One hundred fifteen patients with rectal cancer were treated with oral 5-fluorouracil or Tegafur with preoperative radiotherapy, surgery, and intraoperative electron beam radiation therapy to identify potential pre- and on-treatment characteristics that might be of prognostic value for disease outcome."1.33Prognostic factors for disease-free survival in patients with T3-4 or N+ rectal cancer treated with preoperative chemoradiation therapy, surgery, and intraoperative irradiation. ( Alvarez, E; Calvo, FA; Cortés, J; Del Valle, E; Díaz-González, JA; García-Sabrido, JL; Gómez-Espí, M; Muñoz-Jiménez, F, 2006)
"To describe oncocytic change in rectal cancers that have been treated with chemoradiation before surgery."1.33Rectal adenocarcinoma with oncocytic features: possible relationship with preoperative chemoradiotherapy. ( Chetty, R; Rouzbahman, M; Serra, S, 2006)
"Stage II-III rectal cancer patients received 2 cycles of bolus 5-FU (425 mg/m2) and leucovorin (LV) (20 mg/m2) on days 1-5 q3w followed by oral capecitabine (800 mg/m2 bid) continuously during pelvic radiotherapy (total 50."1.33Capecitabine chemoradiation for rectal cancer after curative surgery. ( Bajetta, E; Beretta, E; Buzzoni, R; Di Bartolomeo, M; Dognini, G; Ferrario, E; Mancin, M; Mariani, L; Valvo, F, 2006)
"The clinical diagnosis of multiple pyogenic granulomas was confirmed by histological examination."1.33Multiple periungual pyogenic granulomas following systemic 5-fluorouracil. ( Cooray, P; Curr, N; Gin, D; Murugasu, A; Saunders, H; Schwarz, M, 2006)
" Taken together, the results suggest that a poloxamer gel system with 5-FU/P188/PG is an effective rectal dosage form for the treatment of both rectal and non-rectal cancers."1.33Poloxamer 188 and propylene glycol-based rectal suppository enhances anticancer effect of 5-fluorouracil in mice. ( Choi, HG; Jeong, TC; Jin, CH; Kim, JA; Lee, YS; Oh, YK; Paek, SH; Park, BC; Xuan, JJ, 2006)
"The files of 89 patients with rectal cancer, 43 treated preoperatively with oral capecitabine and 46 with intravenous 5-FU, were reviewed, and the outcome of the groups was compared."1.33Preoperative chemoradiation in rectal cancer: Retrospective comparison between capecitabine and continuous infusion of 5-fluorouracil. ( Brenner, B; Dreznik, Z; Dror, Y; Fenig, E; Figer, A; Idelevich, E; Loven, D; Nudelman, I; Shani, A; Stemmer, SM; Sulkes, A; Yerushalmi, R, 2006)
"A sample of 83 rectal cancer patients in Dukes' stages B2 or C who started a chemoradiotherapy treatment followed by surgery, have filled in the EORTC core questionnaire QLQC30 and the colorectal module QLQ-CR38, in three moments during the treatment and follow-up periods: at the beginning of the treatment, at the end of the chemoradiotherapy, and after surgery."1.33Quality of Life assessment through the EORTC questionnaires of locally advanced rectal cancer patients treated with preoperative chemo-radiotherapy. ( Arias de la Vega, F; Arraras Urdaniz, JI; Manterola Burgaleta, A; Martínez Aguillo, M; Salgado Pascual, E; Vera García, R; Villafranca Iturre, E, 2006)
"A total of 183 patients with rectal cancer (cT3-T4 or N+) were enrolled in this study."1.33Epidermal growth factor receptor as a predictor of tumor downstaging in locally advanced rectal cancer patients treated with preoperative chemoradiotherapy. ( Cho, MJ; Kim, JM; Kim, JS; Kim, KH; Li, S; Nam, JS; Song, KS; Yeo, SG; Yoon, WH, 2006)
"Tegafur levels were also higher in tumor samples than other sites (mean 3446."1.33Tegafur and 5-fluorouracil pelvic tissue concentrations in rectal cancer patients receiving preoperative chemoradiation. ( Aldaz, A; Alvarado, A; Arranz, JA; Calvo, FA; de la Mata, D; García, R; Giráldez, J; Serrano, J; Zufía, L, 2006)
"Histologic tumor regression (TR) in rectal cancer after preoperative chemoradiotherapy (CT/RT) may be useful as a surrogate end point for early treatment efficacy, but little is known about its prognostic value."1.33Prognostic value of histologic tumor regression, thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase in rectal cancer UICC Stage II/III after neoadjuvant chemoradiotherapy. ( Aust, DE; Baretton, GB; Becker, H; Häusler, P; Jakob, C; Kulle, B; Liersch, T; Meyer, W; Schwabe, W, 2006)
"Forty patients with rectal cancer pretherapeutic UICC stage II/III, receiving preoperative FU-based CT/RT (CAO/ARO/AIO-94 trial) followed by standardized surgery, including total mesorectal excision, were investigated."1.33Lymph node status and TS gene expression are prognostic markers in stage II/III rectal cancer after neoadjuvant fluorouracil-based chemoradiotherapy. ( Aust, DE; Baretton, GB; Becker, H; Ghadimi, BM; Häusler, P; Jakob, C; Kulle, B; Langer, C; Liersch, T; Schwabe, W, 2006)
" We designed a new regimen to evaluate the efficacy and feasibility of weekly low dose CPT-11 combined with 5-FU/l-LV therapy based on an RPMI regimen against advanced and recurrent colorectal cancer."1.33[Evaluation of weekly low-dose CPT-11 combined with 5-FU/l-LV therapy for advanced and recurrent colorectal cancer--preliminary study]. ( Deguchi, Y; Kaneko, I; Kii, E; Murata, T; Sonoda, K; Tsubono, M; Yasuda, K, 2006)
"Perforative rectal cancer was diagnosed, and an emergency laparotomy was done."1.33[A case of advanced rectal carcinoma, preoperative chemo-radiation therapy leading to histological complete response]. ( Aikou, T; Aridome, K; Baba, K; Hatanaka, S; Ishigami, S; Kato, K; Matsumoto, M; Natsugoe, S; Okumura, H; Onohara, S, 2006)
"Capecitabine was not resumed, and the rash resolved in 3 weeks with the use of pyridoxine and Udderly Smooth balm."1.33Hand-foot syndrome variant in a dihydropyrimidine dehydrogenase-deficient patient treated with capecitabine. ( Diasio, R; Elfiky, A; Saif, MW, 2006)
" After that his general condition recovered, and two cycles of neoadjuvant chemotherapy (NAC) by irinotecan combined with 5-fluorouracil and l-leucovorin (IFL) therapy were performed on an outpatient basis."1.33[A case of advanced rectal carcinoma with multiple lung metastases responding to irinotecan combined with 5-fluorouracil and l-leucovorin (IFL) as neoadjuvant chemotherapy (NAC)]. ( Fukada, T; Hasegawa, A; Hashimoto, R; Hayashi, T; Kametaka, H; Kawano, H; Koyama, T; Seike, K; Tanaka, H; Yasuno, K, 2006)
"In patients with locally advanced rectal cancer located 3-6 cm from anal verge who are traditionally treated with abdominoperineal resection, preservation of anal sphincter after preoperative chemoradiation therapy plus complete rectal excision with coloanal anastomosis is feasible and is associated with acceptable morbidity and no mortality."1.32Anal sphincter preservation in locally advanced low rectal adenocarcinoma after preoperative chemoradiation therapy and coloanal anastomosis. ( Fernández, R; Gutiérrez De La Barrera, M; Hernández-Pacheco, F; Labastida, S; Luna-Pérez, P; Rodríguez-Ramírez, S, 2003)
"Initial treatments of locally advanced rectal cancers focus on local control, as local relapse of a rectal cancer is correlated with a high morbidity and mortality."1.32A favourable pathological stage after neoadjuvant radiochemotherapy in patients with initially irresectable rectal cancer correlates with a favourable prognosis. ( Hospers, GA; Mulder, NH; Reerink, O; Szabo, BG; Verschueren, RC, 2003)
"A remission of lymph node metastasis was accurately shown by rES in 17/19 cases (90%) and by CT in 10/12 cases (83%)."1.32[Preoperative diagnostic procedures in locally advanced rectal carcinoma (> or =T3 or N+). What does endoluminal ultrasound achieve at staging and restaging (after neoadjuvant radiochemotherapy) in contrast to computed tomography?]. ( Becker, H; Füzesi, L; Ghadimi, BM; Jakob, C; Langer, C; Liersch, T; Markus, PM; Müller, D; Siemer, A, 2003)
"Irinotecan (CPT11) has established activity against advanced colorectal cancer without cross-resistance with 5-fluorouracil + leucovorin-based therapy."1.32Irinotecan (CPT11) plus high-dose 5-fluorouracil (5-FU) and leucovorin (LV) as salvage therapy for metastatic colorectal cancer (MCRC) after failed oxaliplatin plus 5-FU and LV: a pilot study in Taiwan. ( Chen, PM; Chen, WS; Chiou, TJ; Lin, JK; Liu, JH; Tai, CJ; Wang, WS; Yen, CC, 2003)
"The local recurrence rate of colorectal cancer has been significantly reduced due to the use of combined radiochemotherapy."1.32Feasibility and morbidity of combined hyperthermia and radiochemotherapy in recurrent rectal cancer--preliminary results. ( Abdel-Rahman, S; D hmke, E; Ertl-Wagner, B; Issels, RD; Krych, M; Pachmann, S; Schaffer, M; Schaffer, PM, 2003)
" At both institutions, concurrent chemotherapy consisted of a continuous infusion of 5-fluorouracil (5-FU) at a dosage of 1500 mg/m(2)/week."1.32The addition of continuous infusion 5-FU to preoperative radiation therapy increases tumor response, leading to increased sphincter preservation in locally advanced rectal cancer. ( Birnbaum, EH; Chandra, A; Crane, CH; Delclos, ME; Feig, BW; Fleshman, JW; Janjan, NA; Kodner, IJ; Lin, EH; Lockett, MA; Myerson, RJ; Phan, T; Picus, J; Read, TE; Singh, AK; Skibber, JM; Thames, HD, 2003)
"Pre-operative perfusion in 16 rectal cancer patients achieved a complete response (no tumour in pelvis) in 1 patient and significant tumour regression in 8 patients rendering them potentially resectable."1.32Isolated chemotherapeutic perfusion of the pelvis for advanced rectal cancer. ( Begossi, G; Belliveau, J; Levy, A; Wanebo, HJ, 2003)
"Capecitabine is an oral fluoropyrimidine used for cancer treatment."1.32Capecitabine-related neurotoxicity presenting as trismus. ( Couch, LS; Groteluschen, DL; Mulkerin, DL; Stewart, JA, 2003)
"The study reviewed Stage II and III rectal cancer patients treated with preoperative chemoradiation and resected for cure."1.32Response to preoperative chemoradiation in stage II and III rectal cancer. ( Blatchford, GJ; Brown, CL; Christensen, MA; Haynatzki, GR; Shashidharan, M; Ternent, CA; Thorson, AG, 2003)
"Curative surgery for rectal cancer seldom requires urinary tract resections."1.32Total cystectomies in the surgical treatment of rectal cancer with prior chemoradiation: analysis of postoperative morbidity and survival. ( Chwaliński, M; Nowacki, MP; Oledzki, J; Rogowski, W; Sopyło, R, 2004)
"The treatment of colorectal cancer with administration of a 2-h infusion of calcium folinate followed by a 24-h infusion of 5-fluorouracil (5-FU) is a standard therapy."1.32Catheter occlusion by calcium carbonate during simultaneous infusion of 5-FU and calcium folinate. ( Bruch, HR; Esser, M, 2003)
"Rectal cancer is a common malignant disease and occurs not infrequently in younger men."1.32[Male gonadal dose in adjuvant 3-d-pelvic irradiation after anterior resection of rectal cancer. Influence to fertility]. ( Hensley, F; Piroth, MD; Wannenmacher, M; Zierhut, D, 2003)
"We report a rectal cancer case with liver and lung metastases treated successfully with this protocol."1.32[A case of liver and lung metastases of rectal cancer responding well to 5-FU hepato-arterial infusion (HAI) with combined use of oral UFT]. ( Ebuchi, M; Hasegawa, K; Kato, K; Maruyama, M; Nagahama, T; Shinoura, H; Takashima, I, 2003)
"The accuracy of EUS restaging of rectal cancer after chemoradiation has not been extensively studied and its usefulness is unclear."1.32Accuracy of endoscopic ultrasound for restaging rectal cancer following neoadjuvant chemoradiation therapy. ( Lin, DE; Stryker, SJ; Vanagunas, A, 2004)
"In stage II (T3-4N0) and III (TxN1-2) rectal cancer, adjuvant radiochemotherapy improves overall survival and decreases the rate of local failure compared to only surgical therapy and is regarded as standard for patients with carcinoma of the lower and intermediate rectum."1.32[Principles of postoperative therapy in rectal carcinoma]. ( Folprecht, G; Köhne, CH, 2004)
" After the operation, weekly bolus of 5-fluorouracil combined with levofolinate was carried out."1.32[A case of rectal cancer with distant lymph node metastases completely responding to postoperative chemotherapy with levofolinate combined with 5-fluorouracil]. ( Inoue, M; Jingu, K; Nakajima, Y; Ochiai, T, 2004)
"Twenty-five consecutive patients with rectal cancer were included, with tumor stages (c)T(2-4)N(x)M(0), during the period 1997-1999."1.3218F-FDG positron emission tomography staging and restaging in rectal cancer treated with preoperative chemoradiation. ( Alvarez, E; Arranz, JA; Calvo, FA; Carreras, JL; Desco, M; Domper, M; Martínez-Lázaro, R; Matute, R, 2004)
"In the majority of patients with rectal cancer invading perirectal tissues or lymph nodes, lesions downstages by preoperative chemo radiotherapy."1.32[Preoperative radiation with chemotherapy for rectal cancer: its impact on downstaging of disease and the role of endorectal ultrasound]. ( Juska, P; Pavalkis, D; Pranys, D, 2004)
" For both men and women, overweight and obese patients experience less toxicity associated with adjuvant chemoradiotherapy, suggesting that actual body weight dosing of fluorouracil for obese patients is justified."1.32Impact of body mass index on outcomes and treatment-related toxicity in patients with stage II and III rectal cancer: findings from Intergroup Trial 0114. ( Benson, AB; Brady, D; Cummings, B; Fuchs, CS; Hollis, DR; Macdonald, JS; Mayer, RJ; McCollum, AD; Meyerhardt, JA; Niedzwiecki, D; O'Connell, MJ; Tepper, JE; Willett, C, 2004)
"A total of 145 rectal cancer patients were treated with surgery and postoperative radiochemotherapy."1.32Extracapsular spread of nodal metastasis as a prognostic factor in rectal cancer. ( Berger, J; Heide, J; Krüll, A, 2004)
"One hundred and fifty-five rectal cancer patients undergoing preoperative pelvic external beam radiation therapy and 5-fluorouracil-based chemotherapy followed by rectal resection were identified."1.32Rate of pathologic complete response with increased interval between preoperative combined modality therapy and rectal cancer resection. ( Gittleman, AE; Guillem, JG; Minsky, BD; Moore, HG; Paty, PB; Saltz, L; Shia, J; Temple, L; Weiser, M; Wong, D, 2004)
"Colon and rectal cancer are in France a challenging problem in public health, reaching the second place in cancer related deaths."1.32[Colorectal cancer: what should be the management of primary tumour?]. ( Delpero, JR; Lelong, B; Moutardier, V, 2004)
"We treated 2 patients with colorectal cancer accompanied by liver metastasis who showed favorable response to combined treatment with fluorouracil and l-Leucovorin."1.32[Case report of two colorectal cancer patients with liver metastasis showing favorable response to fluorouracil and l-leucovorin therapy]. ( Aoki, T; Ichimiya, H; Kato, K; Katsumata, K; Okada, K; Wakana, Y, 2004)
"We report a patient with metastatic colon cancer who developed a hypersensitivity reaction to oxaliplatin during the sixth cycle of combination chemotherapy with oxaliplatin, high-dose 5-fluorouracil and leucovorin."1.32Hypersensitivity reactions to oxaliplatin: a case report and the success of a continuous infusional desensitization schedule. ( Chang, MC; Chang, YF; Hsieh, RK; Huang, MJ; Lim, KH; Lin, HC; Lin, J; Su, YW, 2004)
"For synchronous liver metastases from rectal cancer, after extirpation of the primary lesion, a transcatheter arterial embolization was postoperatively performed 3 times at 6-month intervals."1.32[Long-term control of rectal liver metastases by hepatic arterial infusion chemotherapy of 5-fluorouracil and l-leucovorin--a case report]. ( Ishimaru, S; Kanayama, T, 2004)
"To evaluate the effects of 3-dimensional conformal radiation therapy combined with chemotherapy for rectal cancer of postoperative local recurrence."1.32[Effecting observation of 3-dimensional conformal radiotherapy combined with chemotherapy for rectal cancer of postoperative local recurrence]. ( Chen, LH; Wu, DH, 2004)
"Stage 0 rectal cancer disease is associated with excellent long-term results irrespective of treatment strategy."1.32Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results. ( Campos, FG; Gama-Rodrigues, J; Habr-Gama, A; Kiss, DR; Nadalin, W; Perez, RO; Ribeiro, U; Sabbaga, J; Silva e Sousa, AH, 2004)
"Expression of p27 in the residual rectal cancer may therefore identify patients with disease likely to be refractory to standard therapy and for whom investigational approaches should be strongly considered."1.32Expression of p27 in residual rectal cancer after preoperative chemoradiation predicts long-term outcome. ( Guillem, JG; Klimstra, DS; Mazumdar, M; Minsky, BD; Moore, HG; Ruo, L; Saltz, L; Schwartz, GK; Shia, J, 2004)
"30 colorectal cancer patients were enrolled into the study to receive adjuvant chemotherapy 2 weeks after cured resection."1.32[Relationship between dihydropyrimidine dehydrogenase(DPD) activity and toxicity of 5-FU-based adjuvant chemotherapy in colorectal cancer patients]. ( Chen, G; Li, S; Liao, H; Pan, ZZ; Wan, DS; Wang, GQ; Zhou, ZW, 2004)
"Surgical specimens were assessed for rectal cancer regression grade."1.32Preoperative chemoradiotherapy and total mesorectal excision surgery for locally advanced rectal cancer: correlation with rectal cancer regression grade. ( Cunningham, C; Dodds, E; George, BD; Jones, AC; Mortensen, NJ; Warren, BF; Wheeler, JM, 2004)
"The utility of the proposed Rectal Cancer Regression Grade must be tested against long-term outcomes before its value in predicting prognosis and survival can be determined."1.31Quantification of histologic regression of rectal cancer after irradiation: a proposal for a modified staging system. ( Ekanyaka, N; George, BD; Jones, AC; Kettlewell, MG; Kulacoglu, H; Mortensen, NJ; Warren, BF; Wheeler, JM, 2002)
"Capecitabine (Xeloda) is a new orally administered fluoropyrimidine carbamate that was rationally designed to exert its effect by tumor-selective activation."1.31Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer. ( Cho, MJ; Kim, JS; Song, KS; Yoon, WH, 2002)
"We treated a patient with unresectable rectal cancer with multiple liver, pulmonary and lymph node metastases that responded remarkably to pharmacokinetic modulating chemotherapy (PMC)."1.31[A case of unresectable rectal cancer with liver and pulmonary metastases that responded remarkably to pharmacokinetic modulating chemotherapy]. ( Chiba, M; Hayashi, K; Inaba, Y; Kamio, Y; Koyama, M; Ohe, S; Watabe, S, 2002)
"Diarrhea was the major adverse effect of UFT/LV that made patients reduce dosage."1.31Oral uracil/ftorafur (UFT) plus leucovorin as first-line chemotherapy and salvage therapy with weekly high-dose 5-fluorouracil/leucovorin for the treatment of metastatic colorectal cancer. ( Chen, JS; Hsu, KC; Tang, R; Wang, JY; Yang, TS, 2002)
"We report a case of unresectable rectal cancer in a 53-year-old male treated with chemoradiation."1.31[Long-term complete response in a case of unresectable rectal cancer following chemoradiation]. ( Musha, N; Oka, K; Saito, H; Sando, N; Sasaki, M; Setu, M; Setu, Y; Sunami, E, 2000)
" Shaping this infusional 5-FU chemotherapy within the day so that most of the daily dose is delivered around the time of the radiation therapy may further modify the toxic therapeutic ratio of combined modality therapy."1.31Investigation of the comparative toxicity of 5-FU bolus versus 5-FU continuous infusion circadian chemotherapy with concurrent radiation therapy in locally advanced rectal cancer. ( Hrushesky, W; King, V; Rivera, W; Thrall, MM; Wood, P, 2000)
"Diarrhea was the most frequent acute toxicity."1.31Preoperative chemoradiation in fixed distal rectal cancer: dose time factors for pathological complete response. ( Hagihara, PF; John, WJ; Kenady, DE; Marks, G; McGrath, PC; Mohiuddin, M; Regine, WF, 2000)
"Eight patients had synchronous distant metastases."1.31Preoperative radiation with concurrent 5-fluorouracil for locally advanced T4-primary rectal cancer. ( Grabenbauer, GG; Hohenberger, W; Papadopoulos, T; Rödel, C; Sauer, R; Schick, C, 2000)
"Patients with primary rectal cancer deemed eligible for preoperative radiation and 5-fluorouracil-based chemotherapy because of a clinically bulky or tethered tumor or endorectal ultrasound evidence of T3 and/or N1 were prospectively enrolled."1.31Prospective assessment of primary rectal cancer response to preoperative radiation and chemotherapy using 18-fluorodeoxyglucose positron emission tomography. ( Akhurst, T; Cohen, AM; Erdi, Y; Finn, RD; Gollub, MJ; Guillem, JG; Humm, J; Klimstra, DS; Larson, S; Macapinlac, H; Mazumdar, M; Minsky, BD; Paty, PB; Puig-La Calle, J; Ruo, L; Saltz, L; Tickoo, S; Yeung, H, 2000)
"Treatment of a patient with carcinoid metastases in the liver is discussed."1.31Targeted chemoembolization of tumors with poly(2-hydroxyethyl methacrylate) particles. ( Adamyan, A; Gumargalieva, K; Guseinov, E; Horák, D; Kokov, L; Skuba, N; Tchjao, A; Titova, M; Trostenyuk, N; Tsvirkun, V; Vishnevskii, V, 2000)
"The regimen appears active against rectal cancer, and appears to warrant further consideration as a treatment option for this patient population."1.31A pilot study of preoperative continuous infusion 5-fluorouracil, external microwave hyperthermia, and external beam radiotherapy for treatment of locally advanced, unresectable, or recurrent rectal cancer. ( Anscher, MS; Dewhirst, MW; Hurwitz, H; Jowell, P; Lee, C; Prosnitz, LR; Rosner, G; Samulski, T; Tyler, D, 2000)
"A continuous, 24-hour 5-fluorouracil administration was made through the bilateral internal iliac artery at a dosage of 250 mg/m2/day by the subcutaneous reservoir located at both upper legs using a Baxter infusor."1.31Continuous intra-arterial 5-FU chemotherapy in a patient with a repeated recurrence of rectal cancer: report of a case. ( Araki, Y; Inuzuka, K; Isomoto, H; Matsumoto, A; Ogoh, Y; Ozaki, K; Shirouzu, K; Toh, U; Yasunaga, M, 2000)
"We report a case of advanced rectal cancer accompanied by unresectable liver metastasis in which remission has been achieved for 7 years."1.31[A case of advanced rectal cancer with unresectable liver metastasis for which chemotherapy was markedly effective]. ( Baba, H; Kikunaga, H; Matsudo, A; Miura, H; Morisue, A; Nakai, H; Osakabe, Y; Sotome, K; Takao, M, 2000)
"We discovered metastases in 6 patients (6%) after preoperative therapy."1.31[The importance of delay in patients with tumors exemplified by pretreatment of locally advanced rectal carcinoma]. ( Gretschel, S; Rau, B; Riess, H; Schlag, PM; Wust, P, 2000)
"A 67-year-old female with rectal cancer and multiple liver metastases underwent low anterior resection by total mesorectal excision (TME), cholecystectomy and hepatic arterial cannulation in June 1995."1.31[Long survival in a case of unresectable hepatic metastasis from rectal carcinoma treated with second-look hepatectomy plus pharmacokinetic modulating chemotherapy (PMC)]. ( Kusunoki, M; Noda, M; Yamamura, T; Yanagi, H; Yoshikawa, R, 2001)
"Sixty-five patients with rectal cancer underwent tumor resection after preoperative 5-FU-based chemoradiation."1.31Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer. ( Angeletti, S; Arias, F; Azinovic, I; Brugarolas, A; Dominguez, MA; García-Foncillas, J; Illarramendi, JJ; Martínez Monge, R; Martínez, E; Okruzhnov, Y; Salgado, E; Villafranca, E, 2001)
"Two patients were diagnosed with large rectal tumors and localized prostate cancer."1.31External beam radiotherapy for synchronous rectal and prostatic tumors. ( Kapp, DS; King, C; Siu, W; Terris, MK; Wren, SM, 2001)
"Deficiency of dihydropyrimidine dehydrogenase (DPD), the rate-limiting enzyme in 5-fluorouracil (5-FU) catabolism, has been linked to toxic side effects of 5-FU."1.31Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)- related toxicity compared with controls. ( Behnke, D; Häusler, P; Höffken, K; Raida, M; Schwabe, W; Van Gennip, AH; Van Kuilenburg, AB, 2001)
"Severe fatigue was defined as 7-10 on the "worst level of fatigue" item."1.31Fatigue during preoperative chemoradiation for resectable rectal cancer. ( Cleeland, CS; Crane, CH; Engstrom, MC; Guo, H; Janjan, NA; Johnson, BA; Mendoza, TR; Wang, XS, 2001)
"114 patients with rectal cancer were treated by selective preoperative intra-arterial infusion chemotherapy."1.31[Effects of selective preoperative intra-arterial infusion chemotherapy on apoptosis and proliferation of rectal cancer cells]. ( Li, J; Liu, F; Qi, X, 2000)
"Spontaneous apoptosis in rectal cancer may serve as an important predictor of tumor regression from RCT in rectal cancer and as a significant prognosticator of relapse-free survival."1.31Apoptosis as a cellular predictor for histopathologic response to neoadjuvant radiochemotherapy in patients with rectal cancer. ( Bigalke, M; Grabenbauer, GG; Günther, K; Papadopoulos, T; Peters, A; Rödel, C; Rödel, F; Sauer, R; Schick, C, 2002)
"We performed PMC-CPT-11 therapy (modified pharmacokinetic modulating chemotherapy plus irinotecan, or modified PMC) in a case of sigmoid colon cancer with local invasion and multiple hepatic metastases."1.31[A case of hepatic metastasis from rectal carcinoma successfully treated with pharmacokinetic modulating chemotherapy (PMC)-CPT-11 therapy]. ( Chang, W; Kondo, Y; Kosaka, H; Maeda, S; Matsusaka, S; Okada, T; Oriyama, T, 2002)
"Ten patients with invasive distal rectal cancer (six T2, four T3) were treated with preoperative radiotherapy (3600-5040 cGy) with or without 5-fluorouracil based chemotherapy."1.31Preoperative radiation with or without chemotherapy and full-thickness transanal excision for selected T2 and T3 distal rectal cancers. ( Cohen, AM; Guillem, JG; Minsky, BD; Paty, PB; Quan, SH; Ruo, L, 2002)
"Capecitabine is a member of a new class of oral fluoropyrimidines."1.31Capecitabine can induce acute coronary syndrome similar to 5-fluorouracil. ( Andrasch, H; Beck, FJ; Frickhofen, N; Fuhr, HG; Jung, B; Sigmund, M, 2002)
"For locally advanced primary colorectal cancer, our institution has combined intraoperative electron irradiation (IOERT) with external beam irradiation (EBRT) +/- 5-fluorouracil (5-FU) and surgical resection."1.30Locally advanced primary colorectal cancer: intraoperative electron and external beam irradiation +/- 5-FU. ( Cha, S; Devine, R; Dozois, R; Fieck, JM; Gunderson, LL; Haddock, M; Martenson, JA; Nelson, H; O'Connell, MJ; Wolff, B, 1997)
"In patients with stage III colon cancer, adjuvant chemotherapy with fluorouracil and levamisole has been shown to produce a 40 percent reduction in the recurrence rate at a median follow-up of 6."1.30Adjuvant therapy for colon and rectal cancer. ( Ratkin, GA, 1997)
"We retrospectively examined the acute toxicity of (neo-)adjuvant combined treatment for rectal cancer in an attempt to evaluate potential factors that influence the severity of toxic side effects."1.30[The acute toxicity of the simultaneous radiochemotherapy of rectal carcinoma]. ( Fietkau, R; Grabenbauer, GG; Keilholz, L; Kessler, H; Martus, P; Rödel, C; Sauer, R, 1997)
"Three rectal cancer patients were treated with arterial infusion chemotherapy through the internal iliac artery."1.30[Arterial infusion chemotherapy in pelvic space for advanced rectal cancer]. ( Aoyama, H; Fukunaga, T; Imazeki, H; Isono, K; Iwasaki, K; Maeda, T; Matsuzaki, H; Miyazaki, S; Nakajima, K; Okazumi, S; Shinotou, K; Shutou, K; Takayama, W; Takeda, A, 1997)
"He was diagnosed as rectal cancer with multiple liver metastases."1.30[A case of multiple liver metastasis and local recurrence from rectal cancer effectively treated by arterial infusion chemotherapy using low-dose 5-fluorouracil, cisplatin and LV]. ( Endo, Y; Kodama, M; Naitoh, H; Okauchi, H; Tani, T; Yamasaki, M, 1997)
"Mitomycin C suppository was significantly less toxic compared with intravenous delivery, and higher rectal tissue concentrations were observed from 10 to 30 minutes (P < 0."1.30Suppository administration of chemotherapeutic drugs with concomitant radiation for rectal cancer. ( Ackerman, D; Galandiuk, S; Hofmeister, A; LaRocca, R; Lewis, RK; Myers, SR; Paris, KJ; Pokorny, RM; Wrightson, WR, 1997)
"Fluorouracil-induced pneumonitis was subsequently diagnosed."1.30[A case of fluorouracil-induced pneumonitis]. ( Andou, H; Itoh, K; Tsuda, T, 1997)
"5-Fluorouracil, 2600 mg/m2, was administered concurrently with 100 mg/m2 leucovorin over 24 hours of continuous intravenous infusion."1.30Weekly 24-hour infusion of high-dose 5-fluorouracil and leucovorin in patients with advanced colorectal cancer: Taiwan experience. ( Chen, PM; Chen, WS; Chiou, TJ; Fan, FS; Hsieh, RK; Jiang, JK; Lin, JK; Lin, TC; Liu, JH; Wang, WS; Yen, CC, 1998)
"Fifty-five colorectal cancer patients who had continuous intraportal chemotherapy between 1990 and 1993 (treated group) and 130 colorectal cancer patients who did not have portal chemotherapy between 1982 and 1993 (untreated group) were studied to clarify the effects of continuous intraportal chemotherapy on the prognosis."1.30[Continuous intraportal chemotherapy for prevention of metachronous hepatic metastasis in colorectal cancer]. ( Adachi, W; Amano, J; Kajikawa, S; Koide, N; Koike, S; Kuroda, T; Mihara, M; Nakata, S; Watanabe, H; Yazawa, K, 1998)
"Twenty-nine patients with advanced colorectal cancer were divided into four groups, 3 days, 5 days, 7 days, and 10 days."1.30[Enhanced induction of apoptosis of human colorectal cancer cells after preoperative treatment with 5-fluorouracil its relationship to DNA ploidy pattern]. ( Kaibara, N; Kurayoshi, K; Makino, M; Taniguchi, T; Yamane, N, 1998)
"Treatment of colorectal cancers is based on surgery and the prognosis is determined by the locoregional or metastatic tumor spread."1.30[How I treat colorectal cancer. I. Prevention and adjuvant treatment]. ( Bours, V; Fillet, G; Jerusalem, G, 1998)
"5-Fluorouracil is an S-phase-specific, synthetic pyrimidine antimetabolite, which is used as a cytostatic agent for a variety of malignant lesions, either singly or in multidrug regimens."1.30Supraventricular arrhythmia: a complication of 5-fluorouracil therapy. ( Ahmad, M; Aziz, SA; Iqbal, K; Jalal, S; Mohi-ud-Din, K; Tramboo, NA, 1998)
"Patients with resectable rectal cancer who received 20 Gy/5 fractions preoperative radiotherapy to the pelvis had excellent local and distant control of disease."1.30Five fractions of preoperative radiotherapy for selected cases of rectal carcinoma: long-term tumor control and tolerance to treatment. ( Birnbaum, E; Fleshman, J; Fry, R; Genovesi, D; Kodner, I; Lockett, MA; Menteer, J; Myerson, RJ; Picus, J; Read, T; Walz, B, 1999)
"The role in colorectal cancer is less clear, although there are some reports that suggest a benefit."1.30Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer. ( Clingan, P; Horsell, KW; King, DW; Merten, S; Morris, DL, 1999)
"To determine the maximum-tolerated dose (MTD) and recommended dose of irinotecan (CPT-11) in combination with fluorouracil (5-FU) and leucovorin (LV), using a biweekly LV5FU2 regimen and increasing doses of CPT-11, and to assess the efficacy of this combination in pretreated patients with colorectal cancer (CRC)."1.30Irinotecan combined with bolus fluorouracil, continuous infusion fluorouracil, and high-dose leucovorin every two weeks (LV5FU2 regimen): a clinical dose-finding and pharmacokinetic study in patients with pretreated metastatic colorectal cancer. ( Armand, JP; Bexon, A; Bonnay, M; Ducreux, M; Mahjoubi, M; Méry-Mignard, D; Rougier, P; Seitz, JF; Ychou, M, 1999)
"In locally advanced rectal cancer, pre-operative chemo-radiotherapy had a low toxicity profile."1.30Pre-operative chemo-radiotherapy in locally advanced rectal cancer: is this the way of future management? ( Cameron, F; Dewar, J; Einhorn, S; Elsaleh, H; Joseph, D; Latham, M; Levitt, M; Osborne, M; Robbins, P; Van Hazel, G, 1999)
"There was a high expression of PCNA in rectal cancer."1.30[The proper opportunity of surgery for rectal cancer after preoperative adjuvant chemotherapy]. ( Chen, X; Li, G; Li, J; Liu, F; Qi, X; Xu, Z; Ye, X, 1999)
"Patients with hepatic metastases from rectal cancer treated with hepatic artery (HA) chemotherapy have a life expectancy great enough to be at risk for pelvic failure."1.29Pelvic radiation therapy combined with hepatic artery chemotherapy for resected rectal carcinoma with liver metastases. ( Andrews, JC; Cha, C; Ensminger, WD; Lawrence, TS; Robertson, JM, 1996)
"Twenty patients with rectal cancer were treated with combined chemoradiation prior to operation, after pretreatment staging of all lesions with transrectal ultrasound (TRUS)."1.29Preoperative chemoradiation downstages locally advanced ultrasound-staged rectal cancer. ( Blatchford, GJ; Christensen, MA; Meade, PG; Ternent, CA; Thorson, AG, 1995)
"All 1992 phase II colorectal cancer abstracts from the 1992 Proceedings of the American Society of Clinical Oncology were reviewed and analyzed for descriptive and quantitative data and conclusions."1.29The style of early clinical research reporting: what are we saying and how do we say it? ( Gedney, C; Weissman, DE, 1993)
"5-Fluorouracil (5-FU) is a chemotherapeutic agent which has been used to treat many solid tumors including cancers of the breast, ovary, cervix, bladder, prostate gland and gastrointestinal tract."1.29Cardiotoxicity related to 5-fluorouracil chemotherapy: a report of two cases. ( Chao, TY; Wang, WB; Weng, MC, 1995)
"The another patient was 61 years old rectum cancer patient with lung and hepatic metastasis (stage V)."1.29[Low-dose continuous infusion therapy 5-FU and CDDP enabled terminal patients with lung and rectal cancer to remain at home]. ( Hayashi, K, 1994)
"51 patients with metastatic colorectal cancer (stage Dukes D) were treated with intravenous (i."1.29Treatment of advanced colorectal cancer with folinic acid and 5-fluorouracil in combination with cisplatinum. ( Dünser, E; Essl, R; Fritz, E; Mascher, H; Micksche, M; Sagaster, P; Teich, G; Umek, H; Wasilewski, M, 1994)
" 5-Fluorouracil is given in a dosage of 1000 mg/m2/day as a continuous 24-hour infusion for 4 days."1.29Concomitant preoperative radiochemotherapy in operable locally advanced rectal cancer. ( Cellini, N; Coco, C; De Franco, A; Magistrelli, P; Mattana, C; Netri, G; Picciocchi, A; Roncolini, G; Valentini, V; Vecchio, FM, 1994)
"Pharmacokinetic study of anticancer drug is essential for clinical application of cancer chemotherapy."1.29[Clinical application of drug delivery system of anti-cancer drugs--the pharmacokinetics and clinical results]. ( Hagiwara, A; Takahashi, T; Taniguchi, H; Yamaguchi, T, 1993)
"In the majority of patients with rectal cancer invading perirectal tissues or lymph nodes, lesions may be downstaged by preoperative adjuvant therapy."1.29Preoperative adjuvant radiation with chemotherapy for rectal cancer: its impact on stage of disease and the role of endorectal ultrasound. ( Bernini, A; Deen, KI; Madoff, RD; Wong, WD, 1996)
" The aim of this study was to evaluate intraoperative radiation therapy (IORT) (flab technique) combined with preoperative or postoperative radiochemotherapy."1.29Locally advanced rectal cancer: resection and intraoperative radiotherapy using the flab method combined with preoperative or postoperative radiochemotherapy. ( Fink, U; Huber, FT; Molls, M; Siewert, JR; Stepan, R; Zimmermann, F, 1996)
"To identify appropriate candidates with rectal cancer for preoperative chemoradiation therapy, the local recurrence rate and clinicopathological characteristics of 232 patients with rectal cancer undergoing curative resection in our department were investigated."1.29[Preoperative chemoradiation therapy for lower rectal cancer]. ( Iihara, K; Kimura, M; Kitada, M; Murotani, M; Niinobu, T; Nose, T; Ogawa, M; Shibata, T; Takada, T; Takami, M; Tsujinaka, T; Tsukahara, Y; Tsukamoto, F, 1996)
"These two cases suggest that dehydration and electrolyte disturbance from high stomal output could be a serious problem following chemoradiation therapy in patients with an ileostomy."1.29Ileostomy dysfunction with adjuvant chemoradiation for rectal carcinoma requiring in-hospital management: a cause for concern. ( Chen, FC; Mackay, JR; Woods, RJ, 1996)
"Distant metastases occurred in 66 patients (54 percent); five-year rate was 72 percent."1.29Intraoperative electron and external beam irradiation with or without 5-fluorouracil and maximum surgical resection for previously unirradiated, locally recurrent colorectal cancer. ( Cha, S; Devine, R; Dozois, R; Fieck, JM; Gunderson, LL; Haddock, M; Martenson, JA; Nelson, H; O'Connell, MJ; Wolff, B, 1996)
"Palliative treatment of recurrent rectal cancer remains to be a challenge."1.28Intraarterial 5-FU-infusion and simultaneous radiotherapy as palliative treatment of recurrent rectal cancer. ( Kolotas, C; Kuhn, FP; Schmitt, G; Schnabel, T; Zamboglou, N, 1992)
"Twenty patients with rectal cancer underwent the preoperative regimen that consisted of 3,000 cGy delivered in 10 fractions over 12 days with concomitant 5-fluorouracil and mitomycin-C."1.28Advantages of the Papillon protocol in the preoperative treatment of rectal carcinoma. ( Broadwater, JR; Gocio, JC; Hutchins, LF; Klimberg, VS; Lang, NP; Langston, JD; Maners, A; Westbrook, KC, 1992)
"5-fluorouracil (5-FU) was infused continuously through an Infuse-A-Port; 360 mg/m2/day for one week after operation, and 180 mg/m2/day for the following three weeks."1.28[Continuous intra-arterial infusion chemotherapy in colorectal cancer patients with nonresectable metastatic liver cancer]. ( Kubota, Y; Masaki, T; Ooya, M; Sakaguchi, M; Sameshima, S; Sawada, T; Shinozaki, M; Tsuno, N; Uchiyama, M; Watanabe, T, 1992)
"Mitomycin C was given on Day 1 (dose: 15 mg/m2 i."1.28Mitomycin C, 5-fluorouracil and radiation in advanced, locally recurrent rectal cancer. ( Dobrowsky, W, 1992)
"We reported a case of metastatic liver cancer from rectal carcinoma, which was successfully treated by systemic continuous 5-Fluorouracil and intermittent Mitomycin C chemotherapy."1.28[A case report of complete remission of liver metastasis from rectal carcinoma treated with intra-arterial infusion chemotherapy]. ( Noguchi, S; Shibata, N, 1992)
" When 50 U/ml IFN-gamma were combined with 5-FU or FUdR, the antiproliferative effects were synergistic in those cell lines with sensitivity to IFN-gamma as a single agent, but not in the IFN-gamma-insensitive cell lines."1.28The effects of gamma-interferon combined with 5-fluorouracil or 5-fluoro-2'-deoxyuridine on proliferation and antigen expression in a panel of human colorectal cancer cell lines. ( Boven, E; Haisma, HJ; Maas, IW; Pinedo, HM; Schlüper, HM, 1991)
"Presence of hepatomegaly emerged as the more significant (P = 0."1.28Prognostic factors in patients with liver metastases from colorectal carcinoma treated with discontinuous intra-arterial hepatic chemotherapy. ( Ducreux, M; Elias, D; Lasser, PH; Lumbroso, J; Pignon, JP; Rougier, P; Ruffie, P; Tigaud, JM, 1991)
" The case history reported here is discussed in relation to dose and scheduling of mitomycin C, and a safe maximum dosage is suggested."1.28Cancer-associated hemolytic-uremic syndrome with spontaneous resolution. A case report. ( Abdolrahimzadeh, S; Barone, C; Franchi, F; Gozzer, M; Seminara, P, 1991)
"Only two of them bore colonic cancer."1.28Disappearance of hyperplastic polyposis after resection of rectal cancer. Report of two cases. ( Fujita, S; Kusunoki, M; Sakanoue, Y; Shoji, Y; Utsunomiya, J; Yamamura, T; Yanagi, H, 1991)
" The tumor pool of free 5FU in those human tumors that trapped 5FU was determined to have a half-life of 0."1.28Tumor trapping of 5-fluorouracil: in vivo 19F NMR spectroscopic pharmacokinetics in tumor-bearing humans and rabbits. ( Albright, MJ; Atkinson, D; Barker, PB; el-Tahtawy, A; King, M; Ong, R; Presant, CA; Ring, R; Servis, KL; Wolf, W, 1990)
"Twelve patients with advanced colorectal cancer were subjected to alternating cycles of treatment with low immunomodulating doses of recombinant alpha-interferon (alpha IFN) + 5-fluorouracil (5FU) or with 5FU alone."1.28Immunochemotherapy of advanced colorectal cancer with alpha-interferon and 5-fluorouracil. 1. Toxicological studies. ( Bonmassar, E; Bonmassar, G; Cucchiara, G; De Vecchis, L; Lagomarsino Caprino, M; Nunziata, C; Picconi, A; Ricci, F, 1989)
"Patients with inoperable rectal cancer have a remote chance of 5-year survival."1.27Ten years' experience with a multimodality treatment of advanced stages of rectal cancer. ( Wassif, SB, 1983)
" In bioavailability studies of CF p."1.27Phase I-II trial of high-dose calcium leucovorin and 5-fluorouracil in advanced colorectal cancer. ( Campbell, J; Creaven, PJ; Herrera, L; Madajewicz, S; Mittelman, A; Perry, A; Petrelli, N; Rustum, YM, 1984)
" Isolated hyperthermic liver perfusion at 40 degrees C with an average dosage of 1000 mg 5-FU was performed in 32 patients with liver metastases (29 colorectal carcinomas, 2 carcinoids, 1 primary hepatoma)."1.27[Isolated liver perfusion in advanced metastases of colorectal cancers]. ( Aigner, KR; Link, KH; Schoch, P; Schwemmle, K; Tonn, JC; Walther, H, 1984)
"CR was observed in one case of breast cancer, and PR in 29 cases."1.27[Cooperative phase II study of spansule tegafur (SF-SP)]. ( Taguchi, T, 1984)
"Three rectal cancer patients with partial response (PR) were obtained by oral administration of 800-1200 mg/day of SF-SP."1.27[The case studies on oral administration of tegafur encapsulated with slow releasing granule (SF-SP) for three rectal patients]. ( Endo, S; Furukawa, R; Katsumi, S; Mukae, S; Sato, T; Sekine, S; Watanabe, I; Watanabe, S, 1984)
"Two cohorts of rats, 240 with colon cancer and 150 controls, were assessed clinically and immunologically for their response to tumour and its management which was either by surgical excision alone or by surgical excision combined with either adjuvant chemotherapy or immunotherapy."1.27Clinical and in vivo response following surgery or surgery plus adjuvant chemotherapy or immunotherapy for colorectal carcinoma in a rat model. ( House, AK; Maley, MA, 1983)
"Of 29 evaluable patients with breast cancer (six of whom had received prior chemotherapy), one achieved a complete response and five achieved a partial response (total response rate, 21%)."1.27Sequential methotrexate plus 5-FU in advanced breast and colorectal cancers: a phase II study. ( Calman, KC; Crossling, F; Ferguson, C; George, WD; Habeshaw, T; Hutcheon, A; Kaye, SB; McArdle, C; Sangster, G; Smith, D, 1984)
"5-Fluorouracil was administered intraperitoneally in maximally tolerated doses from week 26 onwards and failed to influence significantly the development of either benign or malignant tumours."1.27Chemotherapy of chemically-induced colorectal tumours. ( Gilbert, JM; Kark, AE; Slavin, G; Thompson, EM, 1983)
"However, against colo-rectal and stomach cancer, the response rate was only 25% (2/8) and 28."1.27[Chemotherapy and total body hyperthermia]. ( Kato, N; Yamanaka, N, 1985)
"The chemosensitivity of human colorectal cancer was studied in relation to the biological features of the tumor using a human tumor/nude mouse in-vivo system."1.27Biological features and chemosensitivity of human colorectal cancer xenografted in nude mice. ( Yamada, K, 1987)
" In 10 of these tumors, comparative dose-response curves were obtained."1.27Comparison of 5-FU versus FUDR activity in human colorectal cancer using an in vitro clonogenic assay (HTCA). ( Flentje, D; Flentje, M; Schlag, P, 1986)
" Furthermore the differing levels of 5-FU metabolites in normal and malignant tissue could not be correlated with the pharmacokinetic parameters studied."1.27The relationship between plasma pharmacokinetics and tissue metabolites of 5-fluorouracil (5-FU) in patients with colorectal cancer. ( Chisholm, EM; Finan, PJ; Giles, GR; Woodhouse, L, 1987)
"Effect of this treatment on the pain could be evaluated in 16 patients."1.27Palliation of pelvic recurrence of colorectal cancer with intra-arterial 5-fluorouracil and mitomycin. ( Chuang, VP; Claghorn, L; Mavligit, G; Patt, YZ; Peters, RE; Wallace, S, 1985)
"The mitomycin C and BCNU were alternated monthly at the start of each FUDR cycle."1.27Treatment of metastatic colorectal cancer with hepatic artery combination chemotherapy. ( Cohen, AM; Higgins, J; Schaeffer, N, 1986)
"Sixty-six patients with advanced colorectal cancer were treated with 5-fluorouracil, Mitomycin C, and 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea."1.27The efficacy of 5-fluorouracil, mitomycin C, and methyl CCNU in advanced colorectal cancer. ( Chapman, J; Chinn, B; Demitrish, MM; Enochs, K; Garland, M; Groshko, G; Pederson, B; Rocchio, R; Vaughn, CB; Ward, D, 1986)
" However, increase in tegafur dosage volume did not correlate with 5-FU levels."1.27[5-FU concentration in the blood and tissue of patients with gastric and colorectal cancer after administration of UFT or tegafur]. ( Arima, S; Futami, K; Kinashi, M; Shigeta, M; Shimura, H, 1986)
"The sensitivity of human colorectal cancer to 5-fluorouracil (5-FU) and its derivatives: 1-(tetrahydro-2-furyl)-5-FU (tegafur) and 1-hexylcarbamoyl-5-FU (HCFU) was determined by in vitro succinate dehydrogenase inhibition (SDI) test and in vivo subrenal capsule (SRC) assay."1.27[Human colorectal carcinoma is more sensitive to HCFU than 5-FU and tegafur in in vitro and in vivo drug sensitivity tests]. ( Anai, H; Fukuchi, K; Kusumoto, H; Kusumoto, T; Maehara, Y; Miyamoto, K; Sugimachi, K, 1988)
"Since colorectal cancer tissues are resistant to various antitumor drugs, the chemosensitivity test of HCFU should aid in determining the effects of a particular drug for an individual patient."1.27Colorectal carcinoma in vitro is more sensitive to 1-hexylcarbamoyl-5-fluorouracil compared with six other antitumor drugs: carboquone, Adriamycin, mitomycin C, aclacinomycin A, cisplatin, 5-fluorouracil. ( Anai, H; Kusumoto, H; Kusumoto, T; Maehara, Y; Sugimachi, K, 1988)
"Fifteen patients with stomach cancer and colorectal cancer were orally administered 600 mg of UFT before operation and the concentration of tegafur, 5-fluorouracil (5-FU) and uracil in the tissues and serum were measured by chemical assay."1.27[The serum and tissue concentrations of tegafur, 5-fluorouracil and uracil in patients with gastric and colorectal cancers after oral administration of UFT]. ( Kikuchi, K; Kunii, Y; Mori, Y; Nitta, A; Saitou, T; Takahashi, N, 1988)
"Excisions of metastatic liver cancer were performed in 23 pts and 15 pts had nonresectable metastatic liver cancer."1.27[Results of intra-arterial infusion chemotherapy in colorectal cancer patients with metastatic liver cancer]. ( Hojo, K; Moriya, Y; Sawada, T, 1988)
"Twenty-three patients with advanced colorectal cancer were treated with folinic acid (200 mg/m2/day 1-5 IV bolus injection) and 5-fluorouracil (400 mg/m2/day 1-5 IV in 15 minutes) every 28 days."1.27High-dose folinic acid and 5-fluorouracil in advanced colorectal cancer. ( Bartolucci, R; Brugia, M; Buzzi, F; Di Costanzo, F; Padalino, D, 1988)
"However, it is unfortunate that colorectal cancer screening in young patients is difficult because of the low rates of precancerous states (4%)."1.27Colorectal carcinoma in patients younger than 40 years of age. Montpellier Cancer Institute experience with 78 patients. ( Astre, C; Domergue, J; Ismail, M; Joyeux, H; Pujol, H; Saint-Aubert, B; Solassol, C, 1988)
"The results of combined treatment for rectal cancer including preoperative intraarterial chemotherapy are discussed."1.27[Preliminary results of preoperative regional chemotherapy of cancer of the rectum]. ( Mel'nikov, RA; Mosidze, BA, 1988)
" There have been a number of reports relating the plasma levels of cytotoxic agents with pharmacodynamic parameters."1.27Pharmacokinetics and pharmacodynamics of locoregional 5 fluorouracil (5FU) in advanced colorectal liver metastases. ( Goldberg, JA; Kerr, DJ; McArdle, CS; McKillop, JH; Willmott, N, 1988)
"In patients with colorectal cancer metastatic to the liver, partial response (PR) rates in Regimens I and II were 38% and 62%, respectively."1.27Intra-hepato-arterial chemotherapy with CDDP and 5-FU for metastases to the liver from colorectal and gastric cancers. ( Hamazoe, R; Ishiguro, M; Koga, S; Maeta, M; Murakami, A; Sawada, T; Shimizu, N, 1988)
"32 cases of colon cancer were given I/V 5-fluorouracil for at least one year."1.27Advanced colorectal carcinoma--5 year survival of 76 cases treated at the Department of Therapeutic Radiology, Singapore General Hospital. ( Chia, KB; Chua, EJ; Khor, TH; Sethi, VK; Tan, BC; Tan, TM, 1987)
"Thirty-six patients with advanced colorectal cancer with unequivocal evidence of progression while treated with fluoropyrimidines were treated with a six-day continuous infusion of 500 mg/m2/d of folinic acid initiated 24 hours before a five-day course of 5-FU administered as an intravenous (IV) bolus of 370 mg/m2/d."1.27High-dose continuous infusion folinic acid and bolus 5-fluorouracil in patients with advanced colorectal cancer: a phase II study. ( Bertrand, M; Blayney, DW; Carr, BI; Cecchi, G; Doroshow, JH; Goldberg, D; Leong, L; Margolin, K; Metter, G; Multhauf, P, 1986)
"Colorectal cancer is one of the most resistant tumors to chemotherapy."1.27[Chemotherapy of advanced and recurrent colorectal cancer]. ( Tominaga, T, 1986)
"We treated 45 patients with advanced colon cancer with HDFA and 5-FU for 5 consecutive days."1.27High-dose folinic acid (HDFA) combined with 5-fluorouracil (5-FU) in first line chemotherapy of advanced large bowel cancer. ( Astone, A; Barone, C; Cassano, A; Cavallaro, A; Garufi, C; Grieco, A; Netri, G; Noviello, MR; Ricevuto, E; Rossi, S, 1987)
"In the colorectal cancer group, the response rate for Regimen A was 28."1.27[Sequential methotrexate-5-fluorouracil (MTX-5-FU) treatment of patients with advanced gastric and colorectal cancer. Sequential Methotrexate-5-FU Study Group]. ( Akazawa, S; Futatsuki, K; Kanamaru, R; Miyazaki, T; Murakami, M; Niitsu, Y; Ota, K; Sakai, Y; Wakui, A; Yokoyama, M, 1987)
"Patients with metastatic colorectal cancer confined to the liver received fluorodeoxyuridine (FUdR) through the hepatic artery or through the portal vein."1.27Tumor and liver drug uptake following hepatic artery and portal vein infusion. ( Daly, JM; Kemeny, N; Ridge, JA; Sigurdson, ER, 1987)
"Eleven non-resectable cancer patients have been successfully treated by means of a one-shot and continuous intra-arterial infusion chemotherapy, utilizing an implantable vascular access device (Catheter Access) connected to a continuous infusion pump (Nipro portable syringe infusion pump) via a non-corning needle (Nipro coreless needle set)."1.27[Continuous intra-arterial infusion chemotherapy by implantable catheter access connected with a continuous infusion pump]. ( Agishi, T; Fuchinoue, S; Honda, H; Nakagawa, Y; Nakazawa, H; Ohta, K; Takahashi, K; Teraoka, S, 1987)
"Allopurinol has been shown to ameliorate the myelotoxicity of 5-fluorouracil (5-FU) given as an infusion."1.27Failure of allopurinol to provide clinically significant protection against the hematologic toxicity of a bolus 5-FU schedule. ( Ahmann, FR; Garewal, H, 1986)
" While the in vitro studies failed to reveal any synergism between 5-FU and MND, pharmacokinetic evaluation revealed that 5-FU clearance was significantly reduced (26."1.275-Fluorouracil-metronidazole combination therapy in metastatic colorectal cancer. Clinical, pharmacokinetic and in vitro cytotoxicity studies. ( Ayoub, J; Bardakji, Z; Besner, JG; Jolivet, J; Langelier, Y, 1986)
" Since toxicity is a prominent impediment, the possibility of therapeutic synergy may perhaps be explored at drastically reduced doses of PALA, combined with other modulating measures."1.27Weekly 5-fluorouracil combined with PALA: toxic and therapeutic effects in colorectal cancer. ( Camacho, FJ; Engstrom, PF; Green, MD; Greenwald, ES; Kaplan, BH; Muggia, FM; Wernz, JC, 1987)
" Of the 66 patients with colorectal carcinoma, 44 had not been previously treated with cytostatics and 22 were resistant to previous chemotherapy with 5-FU given either as a single agent or combined with other drugs."1.27Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil combined with high-dose folinic acid. An update. ( Chollet, P; Goldschmidt, E; Machover, D; Mathé, G; Misset, JL; Schwarzenberg, L; Vanden-Bulcke, JM, 1985)
"Five patients with colorectal cancer and unresectable synchronous liver metastases have survived for over five years at this writing."1.27Long-term survivors of colorectal cancer with unresectable hepatic metastases. ( Fujimoto, S; Higuchi, M; Kitsukawa, Y; Miyazaki, M; Okui, K, 1985)
"For many years surgery has been the treatment of choice for squamous cell carcinoma of the anus, but it is now becoming apparent that well-planned definitive radiation therapy combined with chemotherapy may obviate the need for an abdomino-perineal resection."1.27The use of radiation therapy combined with chemotherapy in the management of squamous cell carcinoma of the anus and marginally resectable adenocarcinoma of the rectum. ( Sischy, B, 1985)
"Multimodality therapy for colorectal cancer is composed of surgery, chemotherapy and irradiation; and hyperthermia joins them recently."1.27[Multimodality therapy of colorectal cancer]. ( Fujimoto, S; Miyazaki, M; Okui, K, 1985)
"Thirty-six patients with advanced colorectal cancer whose disease progressed during treatment with 5-fluorouracil (5-FU) chemotherapy were treated with methyl-CCNU and methotrexate."1.27Methyl-CCNU and methotrexate therapy in patients with advanced colorectal cancer after failure of 5-fluorouracil chemotherapy. ( Bazos, MJ; Evans, WK; Myers, R; Shepherd, FA; Zorzitto, ML, 1986)
"In group A for gastric cancer and in group C for colon cancer, the histological response was stronger at the edge of the cancer than at its surface."1.27[Preoperative treatment with 5-fluorouracil (5-FU) in gastric and colorectal cancer]. ( Hashizume, Y; Hirano, M; Iwa, T; Kawaura, Y; Ohmura, K; Sakatoku, M; Takayama, K; Yamada, T, 1985)
" In pharmacokinetic studies in five patients, both schedules produced prolonged plasma beta-half-lives of 5-FU (96-189 minutes)."1.27Phase I evaluation and pharmacokinetic study of weekly iv thymidine and 5-FU in patients with advanced colorectal carcinoma. ( Chun, H; Kemeny, N; Lynch, G; Martin, D; Young, C, 1985)
"Twenty-nine patients with advanced colorectal cancer were treated with methotrexate (MTX) 200 mg/m2 followed 1 h later by fluorouracil (FU) (1000 mg/m2) and 24 h later by oral leucovorin 20 mg every 6 h for six doses."1.27A phase II study of sequential methotrexate and fluorouracil in advanced colorectal cancer. ( Ford, J; Margolese, R; Panasci, L, 1985)
"Allopurinol has been shown to decrease the gastro-intestinal and bone marrow toxicity of 5-fluorouracil."1.27Allopurinol mouthwashes and 5-fluorouracil induced oral toxicity. ( Clark, PI; Slevin, ML, 1985)
"Treatment of colorectal cancer beyond surgical resection has had only minimal success in the past."1.27Colorectal cancer: speculations on the role of intraperitoneal therapy. ( Muggia, FM, 1985)
"Other nonneoplastic gastrointestinal disorders showed an 18% abnormal CSAp titer frequency, of which more than half bordered the upper limit of normalcy."1.26Colon-specific antigen-p (CSAp). I. Initial clinical evaluation as a marker for colorectal cancer. ( Goldenberg, DM; Nelson, MO; Pant, KD; Shochat, D, 1982)
"Sixteen patients with advanced colo-rectal cancer were treated with the combination methyl-CCNU, vincristin, 5-fluorouracil and streptozotocin (MOF-Strepto)."1.26[The combination methyl-CCNU, vincristine, 5-fluorouracil and streptozotocin in the treatment of advanced colo-rectal adenocarcinoma]. ( Cavalli, F; Sessa, C; Togni, P; Varini, M, 1982)
"A retrospective study of 37 colorectal cancer patients with synchronous liver metastases was made."1.26Comparative efficacy of antitumor treatment for liver metastases from colorectal cancer. ( Fujimoto, S; Kitsukawa, Y; Miyazaki, M; Okui, K, 1981)
" Further evaluation of vindesine will require dosage modification."1.26Sequential phase II studies of chemotherapy for colorectal cancer with 5-fluorouracil and vindesine with or without methyl-1,3 cis(2 chloroethyl)-1-nitrosourea. ( Bedikian, AY; Bennetts, RW; Bodey, GP; Karlin, DA; Stroehlein, JR; Valdivieso, M, 1982)
"Twenty-seven patients with liver metastasis from colorectal cancer were treated with intrahepatic arterial chemotherapy and external radiotherapy consisting of 5-fluorouracil (5-FU) (10 mg/kg/day for 8 days), adriamycin (5 mg/m2/day for 7 days) and methotrexate (MTX) (240 mg/m2/X1), combined with 2,100 rads of whole liver irradiation."1.26Therapy of liver tumors metastatic from colorectal cancer with whole-liver radiation combined with 5-FU, adriamycin, and methotrexate. ( Friedman, MA; Phillips, TL; Resser, KJ; Volberding, PA, 1982)
"Two patients with advanced rectal cancer, women aged 73 and 49 years, have survived more than nine years with chemotherapy only and no surgical removal of the disease foci."1.26Long-term survivors with nonresectable advanced carcinoma of the rectum. ( Fukuda, I; Iwanaga, T; Koyama, H; Otani, T; Taniguchi, H, 1981)
"Treatment with Semustine (Methyl-CCNU) resulted in a partial response lasting 15 months."1.26Response of metastatic cloacogenic carcinoma to treatment with semustine. ( Wampler, GL; Zimm, S, 1981)
"Less than 20% of advanced colorectal cancers respond to chemotherapy."1.26Chemotherapy for gastrointestinal malignancy. ( Balint, JA; Van der Veer, LD, 1980)
"46 patients with rectal cancer were treated preoperatively with intrarectal administration of 5-FU emulsion (25 cases) or 5-FU suppositories (21 cases) for a period of 10 days before surgery, and the histological effect of this regimen on the metastatic lesion in the lymph nodes, as well as in the primary tumor was examined."1.26Clinical studies of intrarectal administration of 5-FU emulsion as an adjunct to surgical treatment of rectal cancer. ( Fijita, Y; Kojima, O; Majima, S; Morisawa, K; Nishioka, B; Umehara, M; Watanabe, S; Yamane, E, 1980)
"The role of chemotherapy in colorectal cancer is still not precisely defined."1.26[Incurable colorectal cancer. Possibilities and limits of differentiated therapy (author's transl)]. ( Rauchenberger, B; Winkler, R, 1977)
"A group of 24 patients with colorectal cancer and another group of 28 patients with 13 different primaries were treated."1.26Treatment of hepatic metastases by percutaneous hepatic arterial infusion. ( Minton, JP; Petrek, JA, 1979)
"Eighty-four previously untreated patients with metastatic adenocarcinoma of the large intestine received intravenous ftorafur at a dosage of 2."1.26Phase II evaluation of ftorafur in previously untreated colorectal cancer: a Southwest Oncology Group Study. ( Buroker, T; Groppe, C; Guy, G; Heilbrun, L; Hoogstraten, B; McCracken, J; Padilla, F; Quagliana, J; Vaitkevicius, VK, 1979)
"Relief of pain was noted in two-thirds of the patients."1.26Intraarterial infusion chemotherapy (5-fluorouracil) in patients with inextirpable or locally recurrent rectal cancer. ( Hafström, L; Jönsson, PE; Landberg, T; Owman, T; Sundkvist, K, 1979)
"Fifty-two patients with advanced colorectal cancer were treated with a combination of 5-Fluorouracil (FU) plus methyl-1,3-cis (2-chlorethyl)-1-nitrosourea (MeCCNU)."1.26Lack of effectiveness of combined 5- fluorouracil and methyl-CCNU therapy in advanced colorectal cancer. ( Frei, E; Lokich, JJ; Mayer, RJ; Skarin, AT, 1977)
"Although advanced gastrointestinal cancer is the most commonplace problem encountered by the medical oncologist, this group of diseases has proved exceedingly resistant to past chemotherapy efforts."1.25Clinical management of advanced gastrointestinal cancer. ( Moertel, CG, 1975)
"The roles of lysosomal enzymes in colorectal cancer are discussed."1.25Arylsulfatse B in colorectal cancer. ( Krementz, ET; Meeker, W; Morgan, LR; Samuels, MS; Thomas, W, 1975)
"There was no clinical evidence of carcinoid syndrome."1.255-Hydroxyindole-secreting rectal carcinoid tumour. ( Cheetham, HD; Murray-Lyon, IM; Sandler, M; Watts, JA; Williams, R, 1972)

Research

Studies (2,610)

TimeframeStudies, this research(%)All Research%
pre-1990621 (23.79)18.7374
1990's350 (13.41)18.2507
2000's684 (26.21)29.6817
2010's765 (29.31)24.3611
2020's190 (7.28)2.80

Authors

AuthorsStudies
Tataryn, B1
Kryzhanivska, A1
Holotiuk, V1
Andriiv, A1
Ivantsіv, O1
Catenacci, DVT1
Diefenhardt, M4
Ludmir, EB3
Hofheinz, RD20
Ghadimi, M13
Minsky, BD41
Fleischmann, M1
Fokas, E12
Rödel, C37
Rosati, G4
Corsi, D1
Avallone, A7
Brugnatelli, S1
Dell'Aquila, E1
Cinausero, M1
Aprile, G2
Cicero, G1
Carlomagno, C4
Colombo, A2
Rapisardi, S1
Pinto, C5
Reggiardo, G1
Bilancia, D1
Marin, S1
Pérez-Cordón, L1
Salvà, F1
Camps, M1
Campins, L1
Lianes, P1
Touati, R1
Cohen, R1
Li, N5
Zhu, Y8
Liu, LY2
Feng, YR2
Wang, WL1
Wang, J14
Wang, H7
Li, GF1
Tang, Y6
Hu, C2
Liu, WY2
Ren, H3
Wang, SL3
Wang, WH5
Song, YW5
Liu, YP6
Fang, H5
Lu, NN2
Chen, B2
Qi, SN2
Liu, XF3
Li, YX7
Jin, J8
Lutsyk, M2
Turgeman, I1
Bar-Sela, G1
Lee, J3
Koom, WS8
Byun, HK1
Yang, G2
Kim, MS2
Park, EJ2
Ahn, JB9
Beom, SH4
Kim, HS3
Shin, SJ6
Kim, K3
Chang, JS3
De Felice, F5
Musio, D4
Tombolini, V4
Cortesi, E3
Ichikawa, N2
Homma, S2
Funakoshi, T2
Hattori, M3
Sato, M3
Kamiizumi, Y2
Omori, K2
Nomura, M4
Yokota, R2
Koike, M2
Kon, H2
Takeda, K3
Ishizu, H2
Matsuoka, S2
Hirose, K2
Ishikawa, T8
Murata, R2
Iijima, H3
Yoshida, T5
Minagawa, N3
Takahashi, N5
Taketomi, A2
Rong, X1
Liu, H5
Yu, H2
Zhao, J2
Wang, Y5
Chiloiro, G1
Cusumano, D1
Boldrini, L1
Romano, A1
Placidi, L1
Nardini, M1
Meldolesi, E1
Barbaro, B9
Coco, C14
Crucitti, A1
Persiani, R1
Petruzziello, L1
Ricci, R3
Salvatore, L2
Sofo, L4
Alfieri, S2
Manfredi, R1
Valentini, V27
Gambacorta, MA11
Yamada, K5
Ioka, T2
Suzuki, N3
Yoshida, S5
Tomochika, S1
Matsukuma, S1
Matsui, H2
Shindo, Y2
Tokumitsu, Y2
Watanabe, Y5
Iida, M4
Takeda, S3
Hazama, S2
Ueno, T2
Nagano, H3
Tsujio, G1
Muguruma, K4
Eguchi, S2
Iseki, Y2
Miki, Y3
Yoshii, M1
Fukuoka, T3
Tamura, T4
Shibutani, M3
Nagahara, H6
Toyokawa, T3
Tanaka, H8
Lee, S3
Yashiro, M2
Ohira, M3
Taniguchi, A1
Adachi, Y2
Kimura, Y4
Iitaka, D1
Nagata, T1
Iwata, G1
Yamaoka, N1
Kagawa, Y6
Inoue, A2
Nishizawa, Y4
Kawai, K7
Ohta, T3
Hata, T10
Naito, A2
Komatsu, H1
Miyazaki, Y1
Tomokuni, A1
Motoori, M4
Fujitani, K1
Kato, T14
Takeda, Y4
Murata, K7
Song, JH3
Lee, JH19
Kim, SH13
Um, JW1
McCleary, NJ1
Zhang, S2
Ma, C1
Ou, FS1
Bainter, TM1
Venook, AP3
Niedzwiecki, D6
Lenz, HJ8
Innocenti, F1
O'Neil, BH3
Polite, BN4
Hochster, HS1
Atkins, JN3
Goldberg, RM3
Ng, K1
Mayer, RJ14
Blanke, CD4
O'Reilly, EM2
Fuchs, CS4
Meyerhardt, JA4
Hagiwara, Y1
Yamamoto, Y10
Inagaki, Y1
Tomisaki, R1
Tsuji, M1
Fukuda, S3
Onoda, T1
Suzuki, H4
Niisato, Y1
Tange, Y1
Ikeda, N2
Kobayashi, M4
Akutsu, D1
Yamada, T10
Moriwaki, T3
Narasaka, T1
Tsuchiya, K1
Tamburini, E3
Tassinari, D2
Ramundo, M1
De Stefano, A4
Viola, MG1
Romano, C2
Elia, MT1
Zanaletti, N1
Rudnas, B1
Casadei-Gardini, A1
Delrio, P4
Toma, I1
Granata, V2
Petrucelli, L1
Huang, W2
Zhang, H6
Tian, Y1
Cha, Y1
Xiong, H1
Yuan, X1
Ge, P1
Reyila, A1
Li, XY1
Liu, SY1
Jiang, YX1
Yang, YJ2
Li, XL1
Bian, Y1
Jo, H1
Lee, MS1
Lee, YP1
Kim, H10
Hong, JY1
Park, SH3
Park, JO5
Park, YS9
Lim, HY1
Kang, WK3
Kim, ST1
Hiramatsu, S1
Sugimoto, A1
On, O1
Aomatsu, K1
Liang, YH1
Liang, JT4
Lin, BR1
Huang, J1
Hung, JS1
Lai, SL1
Chen, TC1
Tsai, JH1
Cheng, YM1
Tsao, TH1
Hsu, WL1
Chen, KH1
Yeh, KH1
Matsubara, Y1
Masuishi, T1
Ogata, T1
Nakazawa, T1
Kato, K10
Nozawa, K2
Narita, Y1
Honda, K4
Bando, H2
Taniguchi, H11
Kadowaki, S1
Ando, M5
Tajika, M1
Muro, K4
Mehta, R1
Frakes, J2
Kim, J4
Nixon, A1
Liu, Y4
Howard, L1
Martinez Jimenez, ME1
Carballido, E1
Imanirad, I3
Sanchez, J1
Dessureault, S1
Xie, H4
Felder, S2
Sahin, I1
Hoffe, S2
Malafa, M1
Kim, R3
Punt, CJA3
Kwakman, JJM1
Mol, L1
Kim, JG10
Baik, SH6
Shin, SH1
Park, I1
Lee, MA4
Jeon, SY1
Han, SW1
Kang, MH2
Oh, J1
Kim, JS12
Kim, JY3
Ahn, MS1
Zang, DY2
Bae, BN1
Jo, HJ1
Kim, HK2
Kim, JH27
Yoon, JA1
Kim, DH3
Bello Crespo, M1
Trujillano Ruiz, A1
Gajete Pablos, MA1
Roa García, DM1
Gioseffi, HA1
Jimenez-Fonseca, P1
Salazar, R2
Valenti, V2
Msaouel, P1
Carmona-Bayonas, A1
Nishina, T2
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Iida, F1
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Shinozaki, M1
Tsuno, N1
Uchiyama, M1
Sakaguchi, M1
Dobrowsky, W2
Percarpio, B1
Bitterman, J1
Sabbath, K2
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Ruszkowski, R1
Bowen, J1
Platz, D1
Braumann, D1
Buggisch, P1
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Kleeberg, UR1
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Hiddemann, W1
Knipp, H1
Wilke, H1
Bodenstein, H1
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Meyer zum Büschenfelde, KH1
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van Groeningen, CJ3
Laurensse, EJ1
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Anderson, JH1
Setanoians, A1
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Schaldenbrand, JD1
Siders, DB1
Zainea, GG1
Thieme, ET1
Kanda, T1
Kubo, T1
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Smid, K1
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Clinical Trials (158)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Randomised Multicenter Phase-III-study: Preoperative Radiochemotherapy and Adjuvant Chemotherapy With 5-Fluorouracil Plus Oxaliplatin Versus Preoperative Radiochemotherapy and Adjuvant Chemotherapy With 5-Fluorouracil for Locally Advanced Rect[NCT00349076]Phase 31,256 participants (Actual)Interventional2006-07-31Completed
Prospective Randomized Phase III Study of Concurrent Capecitabine and Radiotherapy With or Without Oxaliplatin as Adjuvant Treatment for Stage II and III Rectal Cancer[NCT00714077]570 participants (Anticipated)Observational2008-04-30Recruiting
Targeted Therapy With or Without Dose Intensified Radiotherapy for Oligo-progressive Disease in Oncogene-addicted Lung Tumours[NCT03256981]Phase 2/Phase 3113 participants (Actual)Interventional2017-11-27Active, not recruiting
Precision Radiation for OligoMetastatIc and MetaStatic DiseasE (PROMISE)-004: Consolidative Use of Radiotherapy to Block (CURB) Oligoprogression[NCT03808662]Phase 2107 participants (Actual)Interventional2019-01-16Active, not recruiting
Stereotactic Radiotherapy for Oligo-Progressive Metastatic Cancer (The STOP Trial): A Randomized Phase II Trial[NCT02756793]90 participants (Actual)Interventional2016-10-31Active, not recruiting
TRAP - Targeted Radiotherapy in Androgen-suppressed Prostate Cancer Patients.[NCT03644303]84 participants (Anticipated)Interventional2018-08-13Recruiting
THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI Guided Radiotherapy[NCT04815694]63 participants (Anticipated)Interventional2021-03-17Recruiting
Phase I Study of Pre-operative Capecitabine and Lenvatinib With External Radiation Therapy in Locally Advanced Rectal Adenocarcinoma[NCT02935309]Phase 120 participants (Actual)Interventional2016-10-14Completed
Randomized Multicentre Phase III Study of Short Course Radiation Therapy Followed by Prolonged Pre-operative Chemotherapy and Surgery in Primary High Risk Rectal Cancer Compared to Standard Chemoradiotherapy and Surgery and Optional Adjuvant Chemotherapy.[NCT01558921]Phase 3920 participants (Actual)Interventional2011-06-21Active, not recruiting
A Phase II Multicenter Randomized Trial Evaluating 3-year Disease Free Survival in Patients With Locally Advanced Rectal Cancer Treated With Chemoradiation Plus Induction or Consolidation Chemotherapy and Total Mesorectal Excision or Non-operative Managem[NCT02008656]Phase 2358 participants (Actual)Interventional2013-11-30Active, not recruiting
Estudo Randomizado de Fase II Com Capecitabina Versus 5-Fluorouracil/Leucovorin em Bolus Associados à Radioterapia no Tratamento Neoadjuvante de câncer de Reto Localmente avançado: INCAGI004.[NCT03428529]Phase 2/Phase 363 participants (Actual)Interventional2011-01-12Completed
Multicenter Randomized Trial Evaluating FOLFIRI Plus Cetuximab Versus FOLFIRI Plus Bevacizumab in First Line Treatment of Metastatic Colorectal Cancer.[NCT00433927]Phase 3568 participants (Anticipated)Interventional2007-01-31Active, not recruiting
Phase 2 Study Comparing Efficacy and Safety of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab[NCT03368859]Phase 270 participants (Actual)Interventional2018-03-20Terminated (stopped due to Study may continue)
Randomized, Open, Multicenter Phase III Study With Capecitabine Plus Bevacizumab Versus Capecitabine Plus Irinotecan Plus Bevacizumab as First-line Therapy in Patients With Metastatic Colorectal Cancer[NCT01249638]Phase 3516 participants (Anticipated)Interventional2010-12-31Recruiting
"Neo-adjuvant FOLFOXIRI and Chemoradiotherapy for High Risk (Ugly) Locally Advanced Rectal Cancer"[NCT04838496]Phase 2128 participants (Anticipated)Interventional2021-06-01Not yet recruiting
Randomized Phase II Study for Evaluation of Efficacy and Safety of Maintenance Treatment With 5-FU/FA Plus Panitumumab vs. 5-FU/FA Alone After Prior Induction Treatment With mFOLFOX6 Plus Panitumumab and Re-induction With mFOLFOX6 Plus Panitumumab in Case[NCT01991873]Phase 2387 participants (Actual)Interventional2014-04-30Completed
Multicentric Phase II-III Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma After a Favorable Response to Induction Chemotherapy[NCT04749108]Phase 2/Phase 31,075 participants (Anticipated)Interventional2021-11-26Recruiting
A Single-Arm Phase II Study in Japan to Assess the Efficacy and Safety of Aflibercept Administered Every Two Weeks in Combination With FOLFIRI in Patients With Metastatic Colorectal Cancer Who Progressed During or Following an Oxaliplatin-Based Regimen[NCT01882868]Phase 262 participants (Actual)Interventional2013-07-31Completed
Drug Response in Patient-derived Organoids Models of Advanced or Recurrent Ovarian Cancer, an Exploratory Research[NCT05290961]30 participants (Anticipated)Observational [Patient Registry]2022-03-09Recruiting
PATHOS Tradeoffs in Patient Decision Making About Rectal Cancer Treatment: Benefits Compared to Quality Of Life.[NCT04925154]192 participants (Anticipated)Observational [Patient Registry]2021-12-13Recruiting
Adjuvant Chemotherapy With FOLFOX After Total Mesorectal Excision for Locally Advanced Rectal Cancer; an Open-label, Multicenter, Prospective, Randomized Phase 3 Trial[NCT02167321]Phase 290 participants (Actual)Interventional2014-12-31Active, not recruiting
Non Inferiority Multicenter Phase III Randomized Trial Comparing Preoperative Chemotherapy Only to Chemotherapy Followed by Chemoradiotherapy for Locally Advanced Resectable Rectal Cancer (Intergroup FRENCH-GRECCAR- PRODIGE)[NCT03875781]Phase 3540 participants (Anticipated)Interventional2019-06-05Recruiting
Short-course Radiation Followed by mFOLFOX-6 Plus COMPOUND 2055269 for Locally-advanced Rectal Adenocarcinoma[NCT03503630]Phase 244 participants (Actual)Interventional2018-07-20Active, not recruiting
A Prospective, Open-Label, Single-Arm and Multicentre Phase II Study to Explore the Efficacy and Safety of Neoadjuvant Cadonilimab Plus Chemotherapy Following Short-Course Radiotherapy in Middle and Lower Locally Advanced Rectal Cancer[NCT05792735]Phase 227 participants (Anticipated)Interventional2023-04-11Recruiting
Rationale and Design of a Prospective, Multicenter Phase Ⅱ Clinical Trial of Safety and Efficacy Evaluation of Long Course Neoadjuvant Chemoradiotherapy Plus Tislelizumab Followed by TME for LARC.[NCT04911517]Phase 250 participants (Anticipated)Interventional2021-06-01Recruiting
Preoperative Hyperfractionated Radiotherapy Versus Combined Radiochemotherapy for Patients With Locally Advanced Rectal Cancer: a Phase III Randomized Trial.[NCT01814969]Phase 3260 participants (Anticipated)Interventional2014-03-31Recruiting
Preoperative Radiochemotherapy With Concurrent Deep Regional Hyperthermia for Locally Advanced Rectal Cancer. A Prospective Phase II Trial[NCT02353858]Phase 278 participants (Actual)Interventional2012-08-31Completed
Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial[NCT05496491]84 participants (Anticipated)Interventional2022-08-30Recruiting
Patient Reported Outcomes Following Cancer of the Rectum[NCT04936581]200 participants (Anticipated)Observational2021-09-01Recruiting
A Phase II Clinical Trial Platform of Sensitization Utilizing Total Neoadjuvant Therapy (TNT) in Rectal Cancer[NCT02921256]Phase 2363 participants (Actual)Interventional2017-01-11Completed
MAgnetic Resonance Imaging Guided LAteral Lymph Node Dissection in Lower REctal Cancer - A Multicenter, Prospective, Registry Study (MALAREC)[NCT04850027]268 participants (Anticipated)Observational [Patient Registry]2021-01-01Recruiting
Evaluation of the Efficacy and Toxicity of Neo-adjuvant Short Course Radiation Therapy Concurrently With Continuous Infusion 5-fluorouracil in the Management of Locally Advanced Rectal Cancer Patients[NCT04370418]Phase 2/Phase 38 participants (Anticipated)Interventional2020-05-01Recruiting
An In Depth Study Evaluating Patterns in the Colon Cancer Patients Clinical Trials[NCT05715905]500 participants (Anticipated)Observational2024-02-29Not yet recruiting
Incidence of The Bowel, Bladder, and Sexual Dysfunction Following Surgery for Colorectal Malignancy[NCT04134104]38 participants (Actual)Observational [Patient Registry]2014-12-31Completed
Phase II: First Line Treatment by FOLFIRINOX for Patients With a Rectum Cancer With Synchronous Non Resectable Metastasis[NCT01674309]Phase 265 participants (Actual)Interventional2012-04-30Completed
A Phase II/III Trial of Neoadjuvant FOLFOX With Selective Use of Combined Modality Chemoradiation Versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection With Total Mesorectal Exci[NCT01515787]Phase 2/Phase 31,194 participants (Anticipated)Interventional2012-06-12Active, not recruiting
Phase I Trial of Dose-escalation Preoperative Short-course Radiotherapy (5×6Gy/7Gy/8Gy) Followed by Neo-adjuvant Chemotherapy in Locally Advanced Rectal Cancer : the FJUHR-01 Trial[NCT03466424]9 participants (Anticipated)Observational2022-08-01Recruiting
Study Protocol - The Development of a Novel Patient Reported Outcomes Measure Committed to the Watch-and-wait Program for Rectal Cancer: An International Delphi Study Protocol[NCT05040646]80 participants (Actual)Observational2021-11-01Completed
Short-course Preoperative Radiotherapy With Consolidating Chemotherapy vs. Preoperative Chemoradiation in Patients With Unresectable Rectal Cancer: Phase III Study[NCT00833131]Phase 3540 participants (Anticipated)Interventional2008-11-30Recruiting
Preoperative Short Course Radiotherapy With Consolidation Chemotherapies and Camrelizumab Followed by Delayed Surgery in Locally Advanced Rectal Cancer[NCT04231552]Phase 1/Phase 230 participants (Actual)Interventional2019-11-10Active, not recruiting
Randomized Phase II Trial of Preoperative Combined Modality Chemoradiation for Distal Rectal Cancer[NCT00006366]Phase 20 participants Interventional2001-02-28Completed
XELOX III. Capecitabine (Xeloda) in Combination With Oxaliplatin (Eloxatin) as First-line Treatment of Patients With Advanced or Metastatic Colorectal Cancer. A Randomized Phase II Study[NCT00212615]Phase 2/Phase 3116 participants (Actual)Interventional2004-02-29Completed
Palliative Radiotherapy Followed by Chemotherapy Against Palliative Surgery in Patients With Rectal Cancer With Unresectable Synchronous Distant Metastases[NCT01157806]Phase 220 participants (Anticipated)Interventional2010-01-31Recruiting
Preoperative Short-course Radiotherapy With Local Boost Versus Conventional Preoperative Short-course Radiotherapy for Rectal Cancer[NCT02498353]100 participants (Anticipated)Interventional2015-07-31Not yet recruiting
Translational Validation Study to Examine KFO179-1 Biomarker Scores for the Prediction and Prognosis of Advanced Primary Resectable Rectal Cancer Stages UICC II-IV, With a 5-FU-based Standard Radiochemotherapy Followed by Total Mesorectal Excision.[NCT03034473]200 participants (Actual)Interventional2011-08-31Active, not recruiting
A Phase I/II Study of Bevacizumab, Erlotinib and 5-fluorouracil With Concurrent External Beam Radiation Therapy in Locally Advanced Rectal Cancer[NCT00307736]Phase 1/Phase 232 participants (Actual)Interventional2006-05-31Completed
Two-Week COurse Versus Conventionally Fractionated Preoperative Chemoradiotherapy In Locally Advanced Rectal Cancer (TwoArc Trial): A Phase III Randomized Clinical Trial[NCT02484040]Phase 3370 participants (Anticipated)Interventional2015-12-31Recruiting
Two Week-course Preoperative Chemoradiotherapy Followed by Delayed Operation for Rectal Cancer: Phase II Multicenter Clinical Trial (KROG 11-02)[NCT01431599]Phase 280 participants (Anticipated)Interventional2011-09-30Recruiting
Multicenter, Phase II Study of Preoperative Chemoradiotherapy With Raltitrexed for Intermediate or Locally Advanced Rectal Cancer in the Fit Elderly[NCT02992886]Phase 268 participants (Actual)Interventional2016-09-30Completed
Early Evaluation of Chemosensitivity for Low-risk Stage II/III Rectal Cancer[NCT03666442]Phase 261 participants (Actual)Interventional2018-06-01Completed
A Multicenter, Prospective, Randomized Clinical Trial to Investigate the Combined Modality Therapy for Locally Advanced Mid/Low Rectal Cancer.[NCT03042000]1,200 participants (Anticipated)Interventional2017-02-28Not yet recruiting
FOUR ARMS PHASE III CLINICAL TRIAL FOR T3-T4 RESECTABLE RECTAL CANCER COMPARING PRE-OPERATIVE PELVIC IRRADIATION TO PRE-OPERATIVE IRRADIATION COMBINED WITH FLUOROURACIL AND LEUCOVORIN WITH OR WITHOUT POST-OPERATIVE ADJUVANT CHEMOTHERAPY[NCT00002523]Phase 31,011 participants (Actual)Interventional1993-04-30Completed
Multicenter Phase II Study of Preoperative Chemoradiotherapy With CApecitabine Plus Temozolomide in Patients With MGMT Silenced and Microsatellite Stable Locally Advanced RecTal Cancer: the CATARTIC Trial[NCT05136326]Phase 221 participants (Anticipated)Interventional2021-12-01Recruiting
Complete Pathologic Response Rectal Cancers EYSAC.1 Study[NCT03351959]1,000 participants (Anticipated)Observational2018-01-01Recruiting
"Radical External Beam Chemoradiation in Patients With Rectal Cancer: a Wait-and-see Approach"[NCT03001362]48 participants (Anticipated)Interventional2015-03-31Recruiting
Chemotherapy Combined With High-dose Radiotherapy for Low Rectal Cancer Using Magnetic Resonance Guided Radiotherapy Linear Accelerator:A Prospective Phase 2 Trial[NCT05338866]58 participants (Anticipated)Observational2022-01-01Enrolling by invitation
Multicenter Randomized Controlled Phase III Trial Comparing Ileostomy Closure Before or After Adjuvant Therapy in Patients Operated for Rectal Cancer[NCT04372992]14 participants (Actual)Interventional2020-09-01Terminated (stopped due to Low accrual - no restart after pandemic suspension)
Chemotherapy or No Chemotherapy in Clear Margins After Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer. A Randomised Phase III Trial of Control Vs Capecitabine Plus Oxaliplatin [CHRONICLE][NCT00427713]Phase 3800 participants (Anticipated)Interventional2004-11-30Completed
The Effect of Neoadjuvant Chemoradiotherapy on Exercise Capacity in Colrectal Cancer Patients[NCT01334593]25 participants (Actual)Observational2011-08-31Completed
A Clinical Trial Comparing Preoperative Radiation Therapy And Capecitabine With or Without Oxaliplatin With Preoperative Radiation Therapy And Continuous Intravenous Infusion Of 5-Fluorouracil With or Without Oxaliplatin In The Treatment Of Patients With [NCT00058474]Phase 31,608 participants (Actual)Interventional2004-07-31Active, not recruiting
Efficacy and Safety of Two Neoadjuvant Strategies With Bevacizumab in Locally Advanced Resectable Rectal Cancer: A Randomized, Non-Comparative Phase II Study[NCT00865189]Phase 291 participants (Actual)Interventional2007-10-23Completed
Randomized Phase II Study of Adjuvant Chemotherapy With 5-FU/Leucovorin vs. Oxaliplatin/5-FU/Leucovorin After Preoperative Chemoradiotherapy With Fluoropyrimidines Followed by Surgery in Patients With Locally Advanced Rectal Cancer[NCT00807911]Phase 2320 participants (Anticipated)Interventional2008-11-30Active, not recruiting
KCSP Trial of cONsolidation Chemotherapy for Locally Advanced Mid or Low Rectal Cancer After neoadjUvant Concurrent chemoraDiothErapy: A Multicenter, Randomized Controlled Trial (KONCLUDE Trial)[NCT02843191]Phase 3358 participants (Anticipated)Interventional2016-12-31Recruiting
Phase II Trial of Weekly Carboplatin-Paclitaxel Adjuvant Chemotherapy After Intensity Modulated Extended-field Chemoradiation in the Treatment of Locally Advanced Cervical Cancer With Para-aortic Positive Nodes[NCT04016142]Phase 221 participants (Actual)Interventional2020-07-15Active, not recruiting
5-Fluorouracil Versus Capecitabine as Perioperative Treatment for Locally Advanced Rectal Cancer. a Randomized Phase III Trial[NCT01500993]Phase 3401 participants (Actual)Interventional2002-03-31Completed
Phase 1/2 Study of Valproic Acid and Short-course Radiotherapy Plus Capecitabine as preoperatIve Treatment in Low-moderate Risk Rectal Cancer[NCT01898104]Phase 1/Phase 2152 participants (Anticipated)Interventional2012-05-31Recruiting
The Prognostic Impact Of The Neutrophil To Lymphocyte Ratio In Patients With Locally Advanced Rectal Cancer[NCT05673343]100 participants (Anticipated)Observational2023-01-04Not yet recruiting
Phase II Study of Preoperative Radiation With Concurrent Capecitabine, Oxaliplatin and Bevacizumab Followed by Surgery and Postoperative 5-FU, Leucovorin, Oxaliplatin (FOLFOX) and Bevacizumab in Patients With Locally Advanced Rectal Cancer[NCT00321685]Phase 257 participants (Actual)Interventional2006-07-25Completed
Phase II Trial of Neoadjuvant Chemoradiation With Bevacizumab for Chinese Locally Advanced Rectal Adenocarcinoma[NCT01554059]Phase 225 participants (Actual)Interventional2012-03-31Completed
Rectal Microbiome Variability Among Rectal Cancer Cohorts Including Complete Clinical Responders, Pathologic Responders, and Early Recurrence[NCT04223102]40 participants (Anticipated)Interventional2020-02-18Active, not recruiting
A Prospective Multicenter Randomized Controlled Trial of the Clinical Efficacy of Neoadjuvant Therapy Based on Organoids Drug Sensitivity Versus Empirical Neoadjuvant Therapy in the Treatment of Advanced Rectal Cancer[NCT05352165]192 participants (Anticipated)Interventional2023-01-01Not yet recruiting
Timing of Rectal Cancer Response to Chemoradiation[NCT00335816]Phase 2248 participants (Anticipated)Interventional2008-08-31Active, not recruiting
Effect of Concurrent Capecitabine-based Long-term Radiotherapy Followed by 4 Cycles XELOX Pre- a Delayed TME Compared With 6 Cycles XELOX post-a Regular Timing TME in Patients With High Risk Rectal Cancer: a Multi-centers, Randomized, Open-Label Trial[NCT03038256]Phase 2244 participants (Anticipated)Interventional2018-01-31Recruiting
Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy. A Prospective Phase II Pilot Trial of the German Rectal Cancer Study Group[NCT03561142]Phase 294 participants (Anticipated)Interventional2018-06-15Recruiting
An Open Label, Non-Randomized Multisite Phase II Trial Combining Bevacizumab, Atezolizumab and Rucaparib for the Treatment of Previously Treated Recurrent and Progressive Endometrial Carcinoma[NCT03694262]Phase 230 participants (Actual)Interventional2019-07-19Completed
The New Challenge of Decoding Rectal Cancer Signatures By Non-Invasive Imaging: A Retrospective Radiomics Study[NCT05331040]350 participants (Anticipated)Observational2020-05-01Active, not recruiting
Pd1 Antibody Sintilimab ± Chemoradiotherapy for Locally Advanced Rectal Cancer[NCT04304209]Phase 2195 participants (Anticipated)Interventional2019-10-28Active, not recruiting
Determination of Microbiological Factors Associated With Poor Response to Neoadjuvant Therapy in Rectal Cancers: Focus on Cyclomodulin-producing Escherichia Coli[NCT04103567]220 participants (Anticipated)Interventional2020-01-14Recruiting
Phase I Study of Pre-operative Continuous 5-FU, and Sorafenib With External Radiation Therapy in Locally Advanced Rectal Adenocarcinoma[NCT01376453]Phase 118 participants (Actual)Interventional2011-06-30Completed
METIMMOX: Colorectal Cancer METastasis - Shaping Anti-tumor IMMunity by OXaliplatin[NCT03388190]Phase 280 participants (Actual)Interventional2018-05-29Active, not recruiting
Study of the Value of the PET/CT in Evaluating the Response of Distal Rectal Cancer to Neoadjuvant Chemoradiation Therapy[NCT00254683]Phase 2100 participants (Anticipated)Interventional2005-09-30Recruiting
Timing to Minimally Invasive Surgery After Neoadjuvant Chemoradiotherapy for Rectal Cancer: a Multicenter Randomised Controlled Trial[NCT03465982]340 participants (Anticipated)Interventional2018-06-05Recruiting
Randomized Control Trial Comparing the Impact of a Lengthening of the Interval Between the Radiochemotherapy and Surgery (7 Weeks vs. 11 Weeks) on Complete Pathological Response in Rectal Cancer[NCT01648894]Phase 3265 participants (Actual)Interventional2012-10-25Completed
A Phase II/III Randomized Controlled Study of Neoadjuvant FOLFOX6 Treatment With or Without Radiation Compared to 5-Fu Based Chemoradiation in Treating Patients With Resectable Rectal Cancer[NCT01211210]Phase 2/Phase 3495 participants (Actual)Interventional2010-06-30Active, not recruiting
Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy of Lower Rectal Cancer With Suspected Local Lymph Node Metastasis[NCT03587480]250 participants (Anticipated)Interventional2018-12-17Recruiting
A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum[NCT00145769]Phase 3326 participants (Actual)Interventional2001-07-31Completed
Validation of the French Version of the Low Anterior Resection Syndrome (LARS) Score for Measuring Bowel Dysfunction After Sphincter-preserving Surgery Among Rectal Cancer Patients[NCT03569488]1,100 participants (Anticipated)Observational2020-01-24Recruiting
A Phase I/II Study of Weekly Intravenous Oxaliplatin in Combination With Oral Daily Capecitabine and Radiation Therapy in the Neoadjuvant Treatment of Rectal Cancer[NCT00086931]Phase 1/Phase 237 participants (Actual)Interventional2003-09-30Completed
MRI Simulation-guided Boost in Short-course Preoperative Radiotherapy (SCPRT) Followed by Consolidation Chemotherapy Versus Long Course Chemoradiation for Unresectable Rectal Cancer[NCT03714490]Phase 2200 participants (Anticipated)Interventional2018-10-23Recruiting
Resource-Sparing Curative Treatment for Rectal Cancer[NCT01459328]Phase 3350 participants (Anticipated)Interventional2009-09-30Recruiting
The Predictive Value of Cytokines on Response to Preoperative Chemoradiotherapy in Patients With Rectal Cancer[NCT02077296]34 participants (Actual)Observational2014-03-31Completed
Phase I Study of Continuous Dosing of Sunitinib in Non GIST Sarcomas With Concomitant Radiotherapy[NCT01308034]Phase 125 participants (Actual)Interventional2011-03-31Completed
Neoadjuvant Chemoradiotherapy Versus Neoadjuvant Chemotherapy For Unresectable Locally Advanced Colon Cancer: An Open, Multi-centered, Randomize Controlled Phase 3 Trial.[NCT03970694]Phase 349 participants (Actual)Interventional2019-05-11Terminated (stopped due to Significant differences in conversion rate as well as R0 resection rate between the two groups.)
Induction Chemotherapy, Preoperative Radiochemotherapy, Consolidation Chemotherapy, Operation and Adjuvant Chemotherapy in the Treatment of Locally Advanced Rectal Cancer- OIGIT 5-01 Phase II Trial[NCT01489332]Phase 260 participants (Anticipated)Interventional2011-10-31Recruiting
Maintenance of Chemotherapy Following Neoadjuvant Chemoradiation Therapy for Distal Rectal Cancer[NCT01613469]Phase 25 participants (Actual)Interventional2011-08-31Terminated (stopped due to Re-eval of patient population)
Induction Chemotherapy With FOLFIRINOX ( 5 Fluorouracil, Oxaliplatine and Irinotecan) Followed by Short Course Radiotherapy in Locally Advanced Rectal Cancer[NCT05868317]Phase 270 participants (Anticipated)Interventional2020-11-01Active, not recruiting
Preoperative Induction Chemotherapy in Combination With Bevacizumab Followed by Combined Chemoradiotherapy in Locally Advanced Rectal Cancer With High Risk of Recurrence- Phase II Pilot Study With Preoperative Administration of Capecitabine (Xeloda), Oxal[NCT01434147]Phase 225 participants (Actual)Interventional2011-10-31Completed
A Phase II Study of Oxaliplatin (Eloxatin) Capecitabine (Xeloda) and Pre-operative Radiotherapy for Patients With Locally Advanced and Inoperable Rectal Cancer.[NCT00220051]Phase 2109 participants (Actual)Interventional2001-11-30Completed
Randomized Phase III Trial Comparing in a Preoperative Schedule the Result of Two Concurrent Chemoradiation Schemes (45 Gy + Capecitabine vs 50 Gy + Capecitabine - Oxaliplatin) on the Rate of Sterilization of the Operative Specimen in Resectable Rectal Ca[NCT00227747]Phase 3598 participants (Anticipated)Interventional2005-11-08Completed
Phase I Study of Preoperative Concurrent Chemo-radiation With Capecitabine in Elderly Rectal Cancer Patients[NCT01584544]Phase 124 participants (Actual)Interventional2011-01-31Completed
Preoperative Radiochemotherapy With IMRT - Simultaneous Integrated Boost in Locally Advanced Rectal Cancer - BISER[NCT02268006]Phase 250 participants (Anticipated)Interventional2014-01-31Recruiting
Follow up and Functional Outcome of Organ Saving Treatment in Patients With Good Response to Neo-adjuvant (Chemo)Radiation for Rectal Cancer[NCT02278653]100 participants (Anticipated)Observational [Patient Registry]2014-03-31Active, not recruiting
Diagnostic Value of Novel MR Imaging Techniques for the Primary Staging and Restaging of Rectal Cancer[NCT01721785]307 participants (Actual)Observational2012-10-31Completed
Preoperative Combined Radiochemotherapy for Patients With Newly Diagnosed, Primary Operable and Locally Advanced Rectal Carcinoma (cT3, Nx, M0) of the Lower and Middle Rectum[NCT00297141]Phase 260 participants (Actual)Interventional2004-10-31Completed
Usefulness of Cell-free DNA Quantification With Fluorescent Assay in Response Evaluation of Palliative Chemotherapy[NCT05227950]100 participants (Anticipated)Observational [Patient Registry]2022-01-01Recruiting
Frequency and Classification of Radiation-induced Diarrhoea in Patients With Prostate and Rectal Cancer During Curative External Radiotherapy[NCT05684432]100 participants (Anticipated)Observational2022-06-01Recruiting
A Phase II Trial of Chemoradiotherapy and Local Excision for uT2uN0 Rectal Cancer[NCT00114231]Phase 290 participants (Actual)Interventional2006-05-31Completed
Randomized Phase II Trial Of Neoadjuvant Combined Modality Therapy For Locally Advanced Rectal Cancer[NCT00081289]Phase 2146 participants (Actual)Interventional2004-03-31Completed
A Phase II Study of 5-Fluorouracil, Bevacizumab (Avastin), and Radiation in the Preoperative or Adjuvant Treatment of Patients With Stage II / III Rectal Cancer[NCT00308516]Phase 266 participants (Actual)Interventional2006-03-31Completed
Minimal Invasive Treatment for Patients With Good Response to Chemoradiation With Selection and Follow-up by MRI: a Single Arm Phase-II Feasibility Study in Rectal Cancer[NCT00939666]28 participants (Actual)Interventional2009-07-01Completed
DETECT: Defining the Target Volume for Endoluminal Radiation Boosting in Patients With Rectal Cancer[NCT04927897]50 participants (Anticipated)Observational2022-08-16Recruiting
Timing To Minimally Invasive Surgery After Neoadjuvant Chemoradiotherapy For Rectal Cancer: A Multicenter Randomized Controlled Trial - Biomarkers SubStudy[NCT03962088]200 participants (Anticipated)Observational2019-04-01Recruiting
Total Neoadjuvant Therapy in Rectal Cancer Treatment[NCT04747951]Phase 4280 participants (Anticipated)Interventional2020-10-30Recruiting
Low-dose Versus Standard-dose Capecitabine Adjuvant Chemotherapy for Chinese Elderly Patients With Stage II/III Colorectal Cancer: A Randomized, Phase 3 Non-inferiority Study[NCT02316535]Phase 3710 participants (Anticipated)Interventional2014-11-30Recruiting
Randomized Open-label Trial of Dose Dense, Fixed Dose Capecitabine Compared to Standard Dose Capecitabine in Metastatic Breast Cancer and Advanced/Metastatic Gastrointestinal Cancers.[NCT02595320]Phase 2200 participants (Actual)Interventional2015-10-05Active, not recruiting
Preoperative Radiotherapy With or Without Concurrent Chemotherapy (5-Fluorouracil and Leucovorin) in T3-4 Rectal Cancers - Randomized Trial[NCT00296608]Phase 3762 participants (Actual)Interventional1993-04-30Completed
Effects of Different Treatment for Anorectal Function of Patients With Rectal Cancer: a Study Protocol for a Prospective, Observational, Controlled, Multicentre Study[NCT05671809]402 participants (Anticipated)Observational [Patient Registry]2023-01-01Not yet recruiting
Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer: A Randomized Phase II Trial of the German Rectal Cancer Study Group[NCT02363374]Phase 2311 participants (Actual)Interventional2015-03-25Completed
A Phase II Trial of Preoperative Capecitabine Plus Irinotecan Followed by Combined Modality Capecitabine and Radiation for Locally Advanced Rectal Cancer: Hoosier Oncology Group GI03-53[NCT00216086]Phase 222 participants (Actual)Interventional2005-05-31Terminated (stopped due to Funding withdrawn)
Retrospective Study Comparing Neoadjuvent Short Course of Radiotherapy to Conventional Chemoradiation in Cancer Rectum[NCT04814784]48 participants (Anticipated)Observational2021-03-31Not yet recruiting
Evaluation of Computed Tomography and Magnetic Diffusion Resonance Imaging in the Preoperative Staging of Colon Cancer[NCT05727007]120 participants (Actual)Interventional2019-01-23Completed
Neoadjuvant Radiotherapy and Capecitabine With or Without Panitumumab in Patients With Advanced, K-ras Unmutated Rectal Cancer. A Randomized Multicenter Phase II Trial[NCT00814619]Phase 268 participants (Actual)Interventional2008-11-30Completed
Capecitabine as Radiosensitising Agent in Neoadjuvant Treatment of Locally Advanced Resectable Rectal Cancer[NCT01152710]Phase 257 participants (Actual)Interventional2004-06-30Completed
Phase 1 Study of Postoperative Capecitabine With Concurrent Radiation in Elderly With Stage II/III Rectal Cancer[NCT01268943]Phase 118 participants (Actual)Interventional2010-11-30Completed
A Pilot Study Using Neoadjuvant Proton Beam Radiation Therapy and Chemotherapy for Marginally Resectable Carcinoma of the Pancreas[NCT00763516]8 participants (Actual)Interventional2009-02-28Completed
Preoperative Radiotherapy With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer: CRAB Phase II Study[NCT00842686]Phase 260 participants (Anticipated)Interventional2009-01-31Active, not recruiting
A Study Using Photon/Proton Beam Radiation Therapy and Chemotherapy for Unresectable Carcinoma of the Pancreas[NCT00685763]13 participants (Actual)Interventional2008-03-31Completed
Phase I Study of Erlotinib and Temsirolimus in Resistant Solid Malignancies[NCT00770263]Phase 146 participants (Actual)Interventional2009-05-31Completed
Proteomic Approach Using Matrix-assisted Laser Desorption/Ionization Tandem Time-of-flight (MALDI-TOF/TOF) of Tumor Response in Rectal Carcinoma After Radiochemotherapy[NCT00855946]46 participants (Actual)Observational2009-05-31Completed
Semen Analysis Following Definitive Treatment of Prostate Cancer With Proton Radiation Therapy Alone[NCT01072513]31 participants (Actual)Interventional2010-03-31Completed
MRI for Response Evaluation After Chemoradiation for Locally Advanced Rectal Cancer[NCT04790227]50 participants (Anticipated)Observational2022-01-31Not yet recruiting
Prediction of Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer.[NCT02439086]20 participants (Anticipated)Interventional2015-09-30Not yet recruiting
A Phase III, Multi-institutional Randomised Trial Comparing Neoadjuvant Chemoradiotherapy (NARCT) and Total Neoadjuvant Therapy (TNT) in Patients With T3 (a/b/c) Rectal Cancer[NCT06097416]Phase 3100 participants (Anticipated)Interventional2024-10-31Not yet recruiting
A Randomized, Phase II Study of Concurrent Radiotherapy and Oxaliplatin, Capecitabine With or Without Cetuximab in Rectal Cancer Tumor Stratified by KRAS Mutation Status.[NCT00795301]Phase 274 participants Interventional2008-07-31Active, not recruiting
Evaluation of Individual Radiosensitivity of Cancer Patients to be Treated by Radiotherapy or Radiochemotherapy Per-operative[NCT02797405]97 participants (Actual)Interventional2016-10-31Terminated (stopped due to Withdrawal of analysis study Partner.)
Surgical Treatment and Molecular Marker Exploration of Locally Recurrent Colorectal Cancer[NCT06114420]500 participants (Anticipated)Observational2023-01-30Recruiting
Pre-operative Radiation Therapy (RT) and Temozolomide (TMZ) in Patients With Newly Diagnosed Glioblastoma. A Phase I Study. (PARADIGMA)[NCT03480867]Phase 10 participants (Actual)Interventional2017-03-31Withdrawn (stopped due to competing study was opened by the surgeon after this trial was opened)
Cetuximab (Erbitux®), Capecitabine and Radiotherapy in Neoadjuvant Treatment of Patients With Locally Advanced Resectable Rectal Cancer: A Phase II Pilot Study[NCT00689702]Phase 243 participants (Actual)Interventional2007-02-28Active, not recruiting
Standardization of Laparoscopic Surgery for Right Hemi Colon Cancer (SLRC)[NCT02942238]582 participants (Anticipated)Interventional2017-01-31Not yet recruiting
Randomized Phase 2 Study Comparing Pathological Responses on Colorectal Cancer Metastases After Preoperative Treatment Combining Bevacizumab With FOLFOX or FOLFIRI[NCT01858649]Phase 260 participants (Actual)Interventional2013-05-31Completed
Randomised Phase 2 Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Treatment Combining Cetuximab With FOLFOX or FOLFIRI in RAS and B-RAF WT Tumors[NCT01858662]Phase 24 participants (Actual)Interventional2014-01-31Terminated (stopped due to due to poor recrutment)
AVF3963s Neoadjuvant Bevacizumab and Carboplatin Followed by Concurrent Bevacizumab, Carboplatin and Radiotherapy in the Primary Treatment of Cervix Cancer[NCT00600210]Phase 20 participants (Actual)Interventional2008-01-31Withdrawn (stopped due to low patient accrual)
Postoperative Evaluation of 5-FU by Bolus Injection vs. 5-FU by Prolonged Venous Infusion Prior to and Following Combined Prolonged Venous Infusion Plus Pelvic XRT vs. Bolus 5-FU Plus Leucovorin Plus Levamisole Prior to and Following Combined Pelvic XRT P[NCT00002551]Phase 31,917 participants (Actual)Interventional1994-03-31Completed
PD1 Antibody Toripalimab and Chemoradiotherapy for dMMR/MSI-H Locally Advanced Colorectal Cancer[NCT04301557]Phase 225 participants (Anticipated)Interventional2020-07-31Recruiting
Lateral Pelvic Lymph Node Dissection After Neoadjuvant Chemo-radiation for Preoperative Enlarged Lateral Nodes in Advanced Low Rectal Cancer: a Phase III Randomized Controlled Trial[NCT02614157]51 participants (Actual)Interventional2016-05-31Terminated (stopped due to The enrollment was too low)
A Pilot Study Investigating Preoperative Proton Radiotherapy for Retroperitoneal Sarcoma[NCT00901836]2 participants (Actual)Interventional2009-05-31Terminated (stopped due to Study closed due to feasability)
Phase II Study Of Radiotherapy And Capecitabine As Pre-Operative Treatment In Patients With Colorectal Cancer[NCT00075556]Phase 20 participants Interventional2002-01-31Active, not recruiting
A Phase I, Open-Label, Non-Randomized, Dose-Escalating Safety, Tolerability and Pharmacokinetic Study of TAS-114 in Combination With S-1 in Patients With Advanced Solid Tumors[NCT02454062]Phase 1120 participants (Actual)Interventional2013-03-31Completed
A Prospective, Randomized, Active-Control, Multi-Center Study Assessing Overall Survival Using Chemotherapy With or Without Impedance-Based Radiofrequency Ablation for Subjects With Colorectal Cancer and Incurable Metastatic Liver Disease, Failing at Leas[NCT00510627]Phase 40 participants (Actual)Interventional2007-08-31Withdrawn (stopped due to Boston Scientific has decided to close the Study.)
A Phase I Trial of Isolated Hepatic Perfusion With Oxaliplatin Followed by Hepatic Arterial Infusion of FUDR and Leucovorin for Patients With Unresectable Colorectal Liver Metastases[NCT01042691]Phase 110 participants (Actual)Interventional2003-05-31Completed
Phase III Multicenter Randomized Controlled Trial of Adjuvant Chemoradiotherapy vs Chemotherapy for Radical Resected Advanced Gastric Carcinoma Concurrent With Lymph Node Metastasis and Lymphovascular Invasion[NCT03680261]Phase 3556 participants (Anticipated)Interventional2018-10-01Not yet recruiting
Prospective Evaluation of 18F-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) in the Multimodality Management of Locally Advanced Primary Rectal Cancer[NCT00004891]149 participants (Actual)Interventional1999-09-30Completed
Development of Quantitative Imaging Biomarkers for Evaluating Sarcoma Patients[NCT02579980]32 participants (Actual)Interventional2015-10-31Completed
Phase I Trial of 5-Fluoro-2'-Deoxycytidine With Tetrahydrouridine[NCT00359606]Phase 158 participants (Actual)Interventional1999-04-30Completed
Phase 0 Trial of [F-18]-5-Fluoro-2'-Deoxycytidine With Tetrahydrouridine[NCT01479348]Early Phase 15 participants (Actual)Interventional2011-11-01Terminated (stopped due to Slow, insufficient accrual.)
A Phase II Study Assessing Efficacy and Safety of TS-1 in Combination With Calcium Folinate in Patients With Heavily Pre-treated Metastatic Colorectal Cancer[NCT03517618]Phase 241 participants (Actual)Interventional2014-07-05Completed
Phase I Trial of Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin Plus Early Postoperative Intraperitoneal Paclitaxel and 5-FU for Peritoneal Carcinomatosis[NCT00001569]Phase 174 participants Interventional1997-01-31Completed
MicroOrganoSphere Drug Screen to Lead Care (MODEL) Precision Oncology Pilot Trial in Colorectal Cancer (CRC)[NCT05189171]180 participants (Anticipated)Observational2022-10-25Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Objective Response Rate (ORR)

ORR is defined as the proportion of participants with a complete response (CR) or partial response (PR) as determined by a investigator assessment based on Response Evaluation Criteria in Solid Tumors (RECIST), Version 1.1. (NCT03368859)
Timeframe: From randomization up to 30 days after last dose of study drug; median time on follow-up was 25.6 (0.3 - 64.4) and 37.6 (0.3 - 66.3) weeks in ABT-165 plus FOLFIRI and Bevacizumab plus FOLFIRI, respectively

Interventionpercentage of participants (Number)
ABT-165 Plus FOLFIRI5.6
Bevacizumab Plus FOLFIRI14.7

Overall Survival (OS)

OS is defined as the time from randomization until death from any cause. (NCT03368859)
Timeframe: Follow up continued until the first occurrence of radiographic progression, death from any cause or termination of the study; median follow-up time was 25.6(0.3-64.4) and 37.6(0.3-66.3) weeks in ABT-165 plus FOLFIRI and Bevacizumab + FOLFIRI, respectively

InterventionMonths (Median)
ABT-165 Plus FOLFIRI7.95
Bevacizumab Plus FOLFIRINA

Progression Free Survival (PFS)

PFS is defined as the time from randomization until the first occurrence of radiographic progression determined by investigator assessment or death from any cause. (NCT03368859)
Timeframe: Follow up continued until the first occurrence of radiographic progression, death from any cause or termination of the study; median follow-up time was 25.6(0.3-64.4) and 37.6(0.3-66.3) weeks in ABT-165 plus FOLFIRI and Bevacizumab + FOLFIRI, respectively

InterventionMonths (Median)
ABT-165 Plus FOLFIRI3.78
Bevacizumab Plus FOLFIRI7.36

Active Metabolite SN-38 / Irinotecan Ratio on Area Under the Concentration Time Curve (Rmet): Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non - compartmental PK analysis of irinotecan and SN-38 in combination with aflibercept and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 1.5, 2, 4.5 and 23 hours post irinotecan infusion on Day 1 of Cycle 1

Interventionratio (Mean)
Aflibercept + FOLFIRI0.0313

Area Under the Concentration Time Curve (AUC) for Free Aflibercept: ITT Population

Sparse blood sampling was performed on 52 participants and additional blood sampling for detailed PK analysis was performed on 10 participants as per protocol. A population PK analysis was performed and an overall data is reported for all the participants. (NCT01882868)
Timeframe: Pre-dose, 1, 4, 24, 336 hours post aflibercept infusion on Day 1 of Cycle 1 for participants with sparse sampling & pre-dose, 1, 2, 4, 8, 24, 48, 168, 336 hours post aflibercept infusion on Day 1 of Cycle 1 for participants with additional sampling

Interventionmcg*day/mL (Mean)
Aflibercept + FOLFIRI304.6

Area Under the Concentration Time Curve (AUC) for Free Aflibercept: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of free aflibercept in combination with irinotecan and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 1, 2, 4, 8, 24, 48, 168 and 336 hours post aflibercept infusion on Day 1 of Cycle 1

Interventionmcg*day/mL (Mean)
Aflibercept + FOLFIRI355

Area Under the Concentration Time Curve From Time 0 to 14 Days Post Start of Infusion (AUC0-14 Day) for Free Aflibercept: ITT Population

Sparse blood sampling was performed on 52 participants and additional blood sampling for detailed PK analysis was performed on 10 participants as per protocol. A population PK analysis was performed and an overall data is reported for all the participants. (NCT01882868)
Timeframe: Pre-dose, 1, 4, 24, 336 hours post aflibercept infusion on Day 1 of Cycle 1 for participants with sparse sampling & pre-dose, 1, 2, 4, 8, 24, 48, 168, 336 hours post aflibercept infusion on Day 1 of Cycle 1 for participants with additional sampling

Interventionmcg*day/mL (Mean)
Aflibercept + FOLFIRI246.9

Clearance at Steady State (CLss) for 5-FU: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of 5-FU in combination with aflibercept and irinotecan in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 2.5, 21 and 45 hours post 5-FU infusion on Day 1 of Cycle 1

Interventionliter/hour (Mean)
Aflibercept + FOLFIRI122

Maximum Observed Plasma Concentration (Cmax) for Free Aflibercept: ITT Population

Sparse blood sampling was performed on 52 participants and additional blood sampling for detailed pharmacokinetic (PK) analysis was performed on 10 participants as per protocol. A population PK analysis was performed and an overall data is reported for all the participants. (NCT01882868)
Timeframe: Pre-dose, 1, 4, 24, 336 hours post aflibercept infusion on Day 1 of Cycle 1 for participants with sparse sampling & pre-dose, 1, 2, 4, 8, 24, 48, 168, 336 hours post aflibercept infusion on Day 1 of Cycle 1 for participants with additional sampling

Interventionmcg/mL (Mean)
Aflibercept + FOLFIRI73.19

Number of Participants With Treatment Emergent Adverse Events (TEAEs)

Adverse event (AE) was defined as any untoward medical occurrence in a participant who received study drug and did not necessarily have to have a causal relationship with the treatment. TEAEs were defined as AEs that developed or worsened during the on--treatment period which was defined as the period from the time of first dose of study treatment until 30 days after the last dose of study treatment. (NCT01882868)
Timeframe: First dose (Day 1 of Cycle 1) of study treatment up to end of treatment visit (30 days after last dose of study treatment) (maximum duration: 77 weeks)

Interventionparticipants (Number)
Aflibercept + FOLFIRI62

Overall Survival (OS)

OS was defined as the time interval from the date of first study drug administration to the date of death due to any cause. If death was not observed, the participant was censored at the last date the participant was known to be alive or the study cut-off date, whichever was first. OS was estimated by Kaplan-Meier estimates. (NCT01882868)
Timeframe: Baseline up to death or study cut--off (maximum duration: 24.7 months)

Interventionmonths (Median)
Aflibercept + FOLFIRI15.59

Percentage of Participants With Overall Response

Overall response in participants was defined as the percentage of participants with confirmed complete response (CR) or partial response (PR) assessed by an independent radiological review committee (IRRC) according to response evaluation criteria in solid tumors (RECIST) version 1.1. CR was defined as disappearance of all target lesions; any lymph node (target or non-target) must have reduction in the short axis to <10 mm; PR was defined as at least 30% decrease in sum of diameters of target lesions, taking as reference the baseline sum diameters. Percentage of participants with overall response and the 95% confidence interval (CI) were provided. The 95% CI was calculated using normal approximation. (NCT01882868)
Timeframe: Baseline and every 6 weeks until DP (maximum duration: 16.4 months)

Interventionpercentage of participants (Number)
Aflibercept + FOLFIRI8.3

Progression Free Survival (PFS)

PFS was defined as the time interval from the date of first study drug administration to the date of first observation of DP or death due to any cause, whichever came first. If death or progression was not observed, the participant was censored at the date of participant's last valid progression-free tumor assessment prior to the study cut-off date. DP for PFS was assessed by the IRRC based on tumor imaging according to RECIST 1.1. Progression in disease was defined as at least 20% increase in the sum of diameters of target lesions compared to smallest sum of diameters on-study with absolute increase of at least 5 mm, progression of existing non-target lesions, or presence of new lesions. PFS was estimated by Kaplan-Meier estimates. (NCT01882868)
Timeframe: Baseline and every 6 weeks until DP or death, due to any cause (maximum duration: 16.4 months)

Interventionmonths (Median)
Aflibercept + FOLFIRI5.42

Steady State Drug Concentration (Css) for 5-FU: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of 5-FU in combination with aflibercept and irinotecan in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 2.5, 21 and 45 hours post 5-FU infusion on Day 1 of Cycle 1

Interventionng/mL (Mean)
Aflibercept + FOLFIRI930

Terminal Elimination Half-life (t1/2z) for Free Aflibercept: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of free aflibercept in combination with irinotecan and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 1, 2, 4, 8, 24, 48, 168 and 336 hours post aflibercept infusion on Day 1 of Cycle 1

Interventiondays (Mean)
Aflibercept + FOLFIRI4.47

Total Body Clearance (CL) for Free Aflibercept: ITT Population

Sparse blood sampling was performed on 52 participants and additional blood sampling for detailed PK analysis was performed on 10 participants as per protocol. A population PK analysis was performed and an overall data is reported for all the participants. (NCT01882868)
Timeframe: Pre-dose, 1, 4, 24, 336 hours post aflibercept infusion on Day 1 of Cycle 1 for participants with sparse sampling & pre-dose, 1, 2, 4, 8, 24, 48, 168, 336 hours post aflibercept infusion on Day 1 of Cycle 1 for participants with additional sampling

Interventionliter/day (Mean)
Aflibercept + FOLFIRI0.8053

Total Body Clearance (CL) for Free Aflibercept: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of free aflibercept in combination with irinotecan and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 1, 2, 4, 8, 24, 48, 168 and 336 hours post aflibercept infusion on Day 1 of Cycle 1

Interventionliter/day (Mean)
Aflibercept + FOLFIRI0.716

Total Body Clearance (CL) for Irinotecan: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of irinotecan in combination with aflibercept and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 1.5, 2, 4.5 and 23 hours post irinotecan infusion on Day 1 of Cycle 1

Interventionliter/hour (Mean)
Aflibercept + FOLFIRI18.3

Volume of Distribution at the Steady State (Vss) for Free Aflibercept: ITT Population

Sparse blood sampling was performed on 52 participants and additional blood sampling for detailed PK analysis was performed on 10 participants as per protocol. A population PK analysis was performed and an overall data is reported for all the participants. (NCT01882868)
Timeframe: Pre-dose, 1, 4, 24, 336 hours post aflibercept infusion on Day 1 of Cycle 1 for participants with sparse sampling & pre-dose, 1, 2, 4, 8, 24, 48, 168, 336 hours post aflibercept infusion on Day 1 of Cycle 1 for participants with additional sampling

Interventionliters (Mean)
Aflibercept + FOLFIRI6.197

Volume of Distribution at the Steady State (Vss) for Free Aflibercept: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of free aflibercept in combination with irinotecan and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 1, 2, 4, 8, 24, 48, 168 and 336 hours post aflibercept infusion on Day 1 of Cycle 1

Interventionliters (Mean)
Aflibercept + FOLFIRI3.53

Volume of Distribution at the Steady State (Vss) for Irinotecan: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of irinotecan in combination with aflibercept and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Predose (prior to aflibercept infusion), 1.5, 2, 4.5 and 23 hours post irinotecan infusion on Day 1 of Cycle 1

Interventionliter (Mean)
Aflibercept + FOLFIRI92.5

Aflibercept Immunogenicity Assessment: Number of Participants With Positive Sample(s) in the Anti-drug Antibodies (ADA) Assay and in the Neutralizing Anti-drug Antibodies (NAb) Assay

Blood samples of participants were analyzed by using a titer-based, bridging immunoassay developed and validated to detect aflibercept ADA in human serum. Samples with positive antibody levels were further analyzed using a validated, non-quantitative, competitive ligand binding assay to detect NAb. (NCT01882868)
Timeframe: Baseline, at any time post baseline and 90 days after the last dose of aflibercept

Interventionparticipants (Number)
At baseline in the ADA assay (n=62)At any time post-baseline in the ADA assay (n=62)At any time post-baseline in the NAb assay (n=62)At 90 days after last dose in the ADA assay (n=50)At 90 days after last dose in NAb assay (n=50)
Aflibercept + FOLFIRI10000

Area Under the Concentration Time Curve (AUC) for Irinotecan and Its Active Metabolite SN-38: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of irinotecan and SN-38 in combination with aflibercept and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 1.5, 2, 4.5 and 23 hours post irinotecan infusion on Day 1 of Cycle 1

Interventionng*h/mL (Mean)
Plasma Irinotecan (n=10)Plasma SN-38 (n=4)
Aflibercept + FOLFIRI17700341

Area Under the Concentration Time Curve From Time 0 to 14 Days Post Start of Infusion (AUC0-14 Day) for Free and VEGF-Bound Aflibercept: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of free and VEGF-bound aflibercept in combination with irinotecan and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Predose (prior to aflibercept infusion), 1, 2, 4, 8, 24, 48, 168 and 336 hours post aflibercept infusion on Day 1 of Cycle 1

Interventionmcg*day/mL (Mean)
Plasma Free-Aflibercept (n=10)Plasma VEGF-Bound Aflibercept (n=5)
Aflibercept + FOLFIRI31223.3

Area Under the Concentration Time Curve From Time 0 to the Time of Last Quantifiable Concentration (AUClast) for Free and VEGF-Bound Aflibercept: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of free and VEGF-bound aflibercept in combination with irinotecan and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Predose (prior to aflibercept infusion), 1, 2, 4, 8, 24, 48, 168 and 336 hours post aflibercept infusion on Day 1 of Cycle 1

Interventionmcg*day/mL (Mean)
Plasma Free-Aflibercept (n=10)Plasma VEGF-Bound Aflibercept (n=8)
Aflibercept + FOLFIRI32124.4

Area Under the Concentration Time Curve From Time 0 to the Time of Last Quantifiable Concentration (AUClast) for Irinotecan and Its Active Metabolite SN-38: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of irinotecan and SN-38 in combination with aflibercept and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 1.5, 2, 4.5 and 23 hours post irinotecan infusion on Day 1 of Cycle 1

Interventionng*h/mL (Mean)
Plasma IrinotecanPlasma SN-38
Aflibercept + FOLFIRI16900344

Maximum Observed Plasma Concentration (Cmax) for Free and Vascular Endothelial Growth Factor (VEGF)-Bound Aflibercept: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of free and VEGF-bound aflibercept in combination with irinotecan and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Predose (prior to aflibercept infusion), 1, 2, 4, 8, 24, 48, 168 and 336 hours post aflibercept infusion on Day 1 of Cycle 1

Interventionmcg/mL (Mean)
Plasma Free-Aflibercept (n=10)Plasma VEGF-Bound Aflibercept (n=8)
Aflibercept + FOLFIRI90.82.83

Maximum Observed Plasma Concentration (Cmax) for Irinotecan and Its Active Metabolite SN-38: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of irinotecan and SN-38 in combination with aflibercept and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Predose (prior to aflibercept infusion), 1.5, 2, 4.5 and 23 hours post irinotecan infusion on Day 1 of Cycle 1

Interventionng/mL (Mean)
Plasma IrinotecanPlasma SN-38
Aflibercept + FOLFIRI222032.2

Terminal Elimination Half-life (t1/2z) for Irinotecan and Its Active Metabolite SN-38: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of irinotecan and SN-38 in combination with aflibercept and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Pre-dose (prior to aflibercept infusion), 1.5, 2, 4.5 and 23 hours post irinotecan infusion on Day 1 of Cycle 1

Interventionhours (Mean)
Plasma Irinotecan (n=10)Plasma SN-38 (n=5)
Aflibercept + FOLFIRI5.1910.3

Time to Reach Maximum Plasma Concentration Observed (Tmax) for Free and VEGF-Bound Aflibercept in Cycle 1: Participants With Additional Blood Sampling for Detailed PK Analysis

In 10 participants of ITT population, additional blood samples were obtained for detailed non-compartmental PK analysis of free and VEGF-bound aflibercept in combination with irinotecan and 5-FU in Cycle 1. (NCT01882868)
Timeframe: Predose (prior to aflibercept infusion), 1, 2, 4, 8, 24, 48, 168 and 336 hours post aflibercept infusion on Day 1 of Cycle 1

Interventiondays (Median)
Plasma Free-Aflibercept (n=10)Plasma VEGF-Bound Aflibercept (n=8)
Aflibercept + FOLFIRI0.0713.97

Neoadjuvant Rectal Cancer (NAR) Score

A linear regression model that controls for the stratification factors (cT-stage and cN-stage) will be used. Mean NAR scores along with standard errors and confidence intervals will be reported by treatment. The NAR score ranges from zero to 100 with lower values corresponding to better prognosis. (NCT02921256)
Timeframe: Baseline to up to 3 years

Interventionscore on a scale (Mean)
Arm Ia (mFOLFOX6, RT, Capecitabine)12.6
Arm II (mFOLFOX6, RT, Capecitabine, Veliparib)13.7
Arm Ib (mFOLFOX6, RT, Capecitabine)14.1
Arm III (mFOLFOX6, RT, Capecitabine, Pembrolizumab)11.5

Rate of Pathologic Complete Response (Nodes and Tumor) ypT0 and ypN0

Pathologic Complete Response means no remaining cancer detectable in the pathology sample. Analyzed by a logistic regression model that controls for the stratification factors (cT-stage and cN-stage). Observed proportions along with confidence intervals will be presented by treatment. (NCT02921256)
Timeframe: Up to 3 years

Interventionpercentage of participants (Mean)
Arm Ia (mFOLFOX6, RT, Capecitabine)21.6
Arm II (mFOLFOX6, RT, Capecitabine, Veliparib)33.8
Arm Ib (mFOLFOX6, RT, Capecitabine)29.4
Arm III (mFOLFOX6, RT, Capecitabine, Pembrolizumab)31.9

Rate of Sphincter Preservation

Sphincter preservation means that the surgical procedure used to remove the tumor did not disturb the sphincter muscle. Analyzed by a logistic regression model that controls for the stratification factors (cT-stage and cN-stage). Observed proportions along with confidence intervals will be presented by treatment. (NCT02921256)
Timeframe: Up to 3 years

Interventionpercentage of participants (Mean)
Arm Ia (mFOLFOX6, RT, Capecitabine)52.5
Arm II (mFOLFOX6, RT, Capecitabine, Veliparib)59.3
Arm Ib (mFOLFOX6, RT, Capecitabine, Pembrolizumab)71.0
Arm III (mFOLFOX6, RT, Capecitabine, Pembrolizumab)59.4

Maximum Tolerated Dose (MTD) of Erlotinib When Administered in Combination With 5-fluorouracil (5-FU), Bevacizumab, and External Beam Radiation Therapy

MTD of Erlotinib was determined using a traditional 3 + 3 dose escalation scheme of three dose levels (50,100,150mg). Successive cohorts of 3-6 patients were enrolled into dose escalation cohorts for 14 day cycles. MTD reflects the highest dose of Erlotinib that had ≤1 out of 6 patients with Dose-Limiting Toxicity (DLT) at the highest dose level below the maximally administered dose. The maximally administered dose is the first dose that causes DLT in >33% of patients. DLT was defined as: Any grade 4 neutropenia, Any grade 3 thrombocytopenia, or Any ≥ grade 3 non-hematologic toxicity that results in greater than 7 days interruption in therapy. (NCT00307736)
Timeframe: 3 years

Interventionmg (Number)
5-FU, Bevacizumab, Erlotinib and Radiation100

Pathologic Complete Response

The number of subjects who achieved a pathologic complete response as determine by pathologist, following completion of the study therapy. Pathologic complete response represents the absence of residual invasive disease in the rectum and in the regional lymph nodes. (NCT00307736)
Timeframe: 3 years

InterventionParticipants (Count of Participants)
Completed Study Therapy9
Underwent Resection10
Treated at MTD7

Percentage of Participants With Disease-free Survival

Summary of disease free survival at 1, 2, and 3 years. Disease free survival is the length of time after primary treatment for cancer ends that the participant survives without any clinical signs or symptoms of that cancer. The data is shown of the percentage of participants still in disease free survival at one, two, and three years. (NCT00307736)
Timeframe: 1, 2, 3 years

Interventionpercentage of participants (Number)
1 Year2 Years3 Years
5-fluorocuracil, Bevacizumab, Erlotinib and Radiation93.483.475.5

Post-operative Complications After Resection of Rectal Cancers Following Preoperative 5-FU, Bevacizumab, Erlotinib, and External Beam Radiation Therapy.

Surgical morbidity following R0 resection with one of the following procedures: abdominal perineal resection, low anterior resection, and low anterior resection with coloanal anastomosis. (NCT00307736)
Timeframe: 3 years

Interventionparticipants (Number)
anastomotic leaksintra-abdominal infectionwound infectionspulmonary embolussmall bowel obstructionurinary obstruction/retentionfever
Surgery, 5-fluorocuracil, Bevacizumab, Erlotinib and Radiation4221151

Summary of Grade 3 or Greater Toxicity

"Summary of grade 3 or greater toxicity by grade and type. All adverse events were evaluated using National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 3.0.~Grade 3: Severe or medically significant but not immediately life threatening; hospitalization or prolongation of hospitalization indicated; disabling; limiting self care activities of daily living.~Grade 4 Life-threatening consequences; urgent intervention indicated." (NCT00307736)
Timeframe: 3 years

,
Interventionparticipants (Number)
LymphopeniaDiarrhea w/o prior colostomyHypophosphatemiaRash: acne/acneiformALT-SGPTAST-SGOTCardiac-ischemiaColitisDehydrationFatigueFebrile neutropeniaHypertensionHyperuricemiaHypokalemiaHyponatremiaMuco/stomatitis (symptom) oral cavityMuco/stomatitis by exam-oral cavityProteinuriaRadiation dermatitisRash/desquamationRectum-pain
Grade 31663211111101011111111
Grade 4500000000010100000000

Disease-Free Survival (DFS)

The DFS was defined as the time from the first treatment intake to disease recurrence assessed (second primary cancer, local or distant recurrence, distant metastases) or death from any cause. The DFS was analyzed using Kaplan-Meier method. (NCT00865189)
Timeframe: From first time of the treatment administration to the date of second cancer, local or regional recurrence, distant metastasis or death from any cause (up to approximately 6 years)

Interventionmonths (Median)
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)68.3
Arm B (Bevacizumab, Chemoradiotherapy)NA

Number of Cycles of Chemotherapy

(NCT00865189)
Timeframe: Arm A: Week 16 to Week 23; Arm B: Week 1 to Week 7

Interventioncycles (Mean)
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)4.4
Arm B (Bevacizumab, Chemoradiotherapy)4.8

Number of Cycles of Induction Chemotherapy

(NCT00865189)
Timeframe: 6 cycles (12 weeks; cycle length = 14 days)

Interventioncycles (Mean)
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)5.8

Number of Cycles of Radiotherapy

(NCT00865189)
Timeframe: Arm A: Week 16 to Week 23; Arm B: Week 1 to Week 7

Interventioncycles (Mean)
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)4.5
Arm B (Bevacizumab, Chemoradiotherapy)5.0

Overall Survival

The overall survival was defined as the time from the first treatment intake to death from any cause. (NCT00865189)
Timeframe: From the first treatment administration to the date of death (up to approximately 6 years)

Interventionmonths (Median)
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)NA
Arm B (Bevacizumab, Chemoradiotherapy)NA

Percentage of Participants Who Died

(NCT00865189)
Timeframe: Baseline up to approximately 6 years

Interventionpercentage of participants (Number)
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)8.7
Arm B (Bevacizumab, Chemoradiotherapy)24.4

Percentage of Participants With Second Cancer, Local or Regional Recurrence, Distant Metastasis, or Death

(NCT00865189)
Timeframe: Baseline up to approximately 6 years

Interventionpercentage of participants (Number)
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)30.4
Arm B (Bevacizumab, Chemoradiotherapy)33.3

Percentage of Participants With Surgery

The surgery involving a radical rectal excision using the TME technique. (NCT00865189)
Timeframe: Arm A: approximately 28-31 weeks after initiation of treatment; Arm B: approximately 13-15 weeks after initiation of treatment

Interventionpercentage of participants (Number)
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)91.3
Arm B (Bevacizumab, Chemoradiotherapy)97.8

Percentage of Participants With Tumor Sterilization Defined by ypT0-N0

Tumor sterilization was defined as the absence of residual tumor cells in the resected specimen including lymph nodes (ypT0-N0). The rate of sterilization of the tumoral specimen was assessed after surgery on the surgical specimen by local review. Analyses were performed for participants who have been operated as defined by the protocol (within the study and TME technique) and for all participants who have been operated. Reported is the percentage of participants with tumor sterilization. (NCT00865189)
Timeframe: After surgery (Arm A: approximately 28-31 weeks after initiation of treatment; Arm B: approximately 13-15 weeks after initiation of treatment)

Interventionpercentage of participants (Number)
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)23.8
Arm B (Bevacizumab, Chemoradiotherapy)11.4

Percentage of Participants With Local and Distant Recurrences

The percentage of participants with a recurrence was described by type of recurrence (local and distant recurrence). (NCT00865189)
Timeframe: After surgery (Arm A: approximately 28-31 weeks after initiation of treatment; Arm B: approximately 13-15 weeks after initiation of treatment)

,
Interventionpercentage of participants (Number)
Local recurrenceDistant recurrence
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)2.217.4
Arm B (Bevacizumab, Chemoradiotherapy)6.713.3

Percentage of Participants With Tumor Down-Staging (ypT0-pT2)

A participant with a downstaging was defined as a participant with T3 (T describes the size of the original [primary] tumor) at inclusion and T2 or T1 or T0 after surgery, or with N+ (N describes lymph nodes involvement) at inclusion and N- after surgery and if T is equal at inclusion and after surgery. The clinical tumor-node-metastasis (cTNM) classification was used at inclusion and the pathological staging tumor and nodes (ypTN) classification after surgery. Reported is the percentage of participants with tumor downstaging of the surgical specimen according to the local review and centralized review. (NCT00865189)
Timeframe: After surgery (Arm A: approximately 28-31 weeks after initiation of treatment; Arm B: approximately 13-15 weeks after initiation of treatment)

,
Interventionpercentage of participants (Number)
Downstaging, local review (n=41, 44)Downstaging, centralized review (n=39, 43)
Arm A (Bevacizumab, Induction Chemotherapy, Chemoradiotherapy)65.964.1
Arm B (Bevacizumab, Chemoradiotherapy)54.555.8

5-year Overall Survival Rate

Overall survival is defined as time from registration to death from any cause. 5-year overall survival rate is estimated using Kaplan-Meier method. (NCT00321685)
Timeframe: survival follow-up began after post-operative chemotherapy, assessed every 3 months for patients 3-5 years from registration, every 6 months for patients 5-10 years from registration and every 12 months for patients 10 years from registration

Interventionpercentage of participants (Number)
Arm I80

5-year Recurrence-free Survival Rate

Recurrence free survival is defined as time from surgery to disease recurrence or death without recurrence (whichever occurred first) among resected patients. 5-year recurrence-free survival rate is estimated using Kaplan-Meier method, with 90% confidence interval calculated using Greenwood's formula. (NCT00321685)
Timeframe: recurrence follow-up began after post-operative chemotherapy, assessed every 3 months for patients 3-5 years from registration, every 6 months for patients 5-10 years from registration and every 12 months for patients 10 years from registration

Interventionpercentage of participants (Number)
Arm I81

Pathologic Complete Response Rate

Pathologic complete response to preoperative therapy was determined at the time of surgical resection. Pathologic complete response (pCR) is defined as no evidence of invasive cells on pathologic examination of the primary rectal cancer (or tissue from the area where the tumor had been if there is a complete clinical response). Pathologic complete response rate is calculated as number of patients achieving pathologic complete response divided by all eligible and treated patients (NCT00321685)
Timeframe: Assessed at surgery time

Interventionpercentage of participants (Number)
Arm I17

Resection Rate for T3 Rectal Cancers

Resection rate is defined as number of patients with T3 rectal cancer who underwent curative surgical resection among all eligible and treated patients with T3 rectal cancers (NCT00321685)
Timeframe: Assessed at surgery time

Interventionpercentage of participants (Number)
Arm I92

Resection Rate for T4 Rectal Cancers

Resection rate is defined as number of patients with T4 rectal cancer who underwent curative surgical resection among all eligible and treated patients with T4 rectal cancers (NCT00321685)
Timeframe: Assessed at surgery time

Interventionpercentage of participants (Number)
Arm I75

Number of Participants Experienced Dose Limited Toxicity

Dose related toxicity is defined as follows:1. luecopenia > grade 2; granular cell decrease > grade 2; anemia > grade 1; platelet > grade 1;SGPT/SGOT elevation > grade 1; ALP > grade 1; GGT > grade 1; Tbil > grade 1;renal function damag > grade 2;Non-gradular cell decreased fever > grade 1;nausea/vomiting > grade 1; fatigue > grade 2; weight loss > grade 2;gastritis > grade 2; dairrea > grade 2; abdominal pain > grade 2; upper gastrointestinal bleeding > grade 1;other toxic reaction > grade 2;KPS < 50 during the treatment (NCT01584544)
Timeframe: up to 7 weeks from start of the treatment

Interventionparticipants (Number)
1000mg0
1200mg1
1350mg1
1500mg0
1650mg1

3-Year Disease-free Survival

The primary endpoint was 3-year disease-free survival (DFS). Evidence of local recurrence, distant metastasis, or death from any cause within 3 years counted as events in the time-to-event Kaplan-Meier analysis of disease-free survival. (NCT00114231)
Timeframe: Up to 3 years

Interventionpercentage of patients (Number)
Treatment (Capecitabine, Oxaliplatin, Radiotherapy, Surgery)88.2

Local Recurrence Rate

The local recurrence rate (percentage) is defined as the percentage of patients who had local recurrence as initial sites of failure at the end of follow-up. (NCT00114231)
Timeframe: Up to 5 years

Interventionpercentage of patients (Number)
Treatment (Capecitabine, Oxaliplatin, Radiotherapy, Surgery)4

R0 Resection Rate (Negative Margin Rate)

The rate (percentage) of patients with negative resection margins after undergoing local excision is reported below. (NCT00114231)
Timeframe: At time of surgery

Interventionpercentage of patients (Number)
Treatment (Capecitabine, Oxaliplatin, Radiotherapy, Surgery)98.7

Rate of Pathologic Complete Response of the Primary Tumor

The rate (percentage) of patients with pathologic complete response (pCR) is reported below. Pathologic response will be determined by comparing tumor width and stage in the surgical specimen with the same parameters as determined by pre-CRT ERUS: PATHOLOGIC COMPLETE RESPONSE (pCR): no residual tumor. (NCT00114231)
Timeframe: Up to 5 years

Interventionpercentage of patients (Number)
Treatment (Capecitabine, Oxaliplatin, Radiotherapy, Surgery)44

Morbidity and Mortality Rate

Morbidity and mortality after neoadjuvant cheoradiotherapy and local excision. (NCT00114231)
Timeframe: Up to 30 days

Interventionpercentage of patients (Number)
MortalityMorbidity
Treatment (Capecitabine, Oxaliplatin, Radiotherapy, Surgery)610

Change From Baseline in EORTC QLQ-CR38 Defecation Symptom Score at Completion of Chemoradiation

"The defecation symptom score is calculated from seven symptom questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-CR38. The question responses range from 1 not at all to 4 very much such that a higher response indicates worse symptoms. The mean of these responses is linearly transformed to a range of 0 (best) to 100 (worst). Change from baseline is calculated as the time point value - baseline value and a decrease from baseline indicates improvement in symptoms. A negative number indicates improvement in symptoms." (NCT00081289)
Timeframe: Baseline and completion of chemoradiation, approximately 6-8 weeks from randomization

Interventionscore on a scale (Mean)
Neoadjuvant Chemoradiation With Irinotecan4.8
Neoadjuvant Chemoradiation With Oxaliplatin8.8

Change From Baseline in EORTC QLQ-CR38 Defecation Symptom Score at Post-operative Chemotherapy

"The defecation symptom score is calculated from seven symptom questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-CR38. The question responses range from 1 not at all to 4 very much such that a higher response indicates worse symptoms. The mean of these responses is linearly transformed to a range of 0 (best) to 100 (worst). Change from baseline is calculated as the time point value - baseline value and a decrease from baseline indicates improvement in symptoms. A negative number indicates improvement in symptoms." (NCT00081289)
Timeframe: Baseline and completion of post-operative chemotherapy, approximately 32 to 40 weeks from randomization based on 18 weeks of post-operative chemotherapy

Interventionscore on a scale (Mean)
Neoadjuvant Chemoradiation With Irinotecan-1.6
Neoadjuvant Chemoradiation With Oxaliplatin14.6

Change From Baseline in EORTC QLQ-CR38 Defecation Symptom Score at Two Years

"The defecation symptom score is calculated from seven symptom questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-CR38. The question responses range from 1 not at all to 4 very much such that a higher response indicates worse symptoms. The mean of these responses is linearly transformed to a range of 0 (best) to 100 (worst). Change from baseline is calculated as the time point value - baseline value and a decrease from baseline indicates improvement in symptoms. A negative number indicates improvement in symptoms." (NCT00081289)
Timeframe: Baseline and two years

Interventionscore on a scale (Mean)
Neoadjuvant Chemoradiation With Irinotecan0.4
Neoadjuvant Chemoradiation With Oxaliplatin-1.6

Change From Baseline in EORTC QLQ-CR38 Gastro-intestinal Symptom Score at Completion of Chemoradiation

The gastro-intestinal (GI) symptom score is calculated from five symptom questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-CR38. The question responses range from 1 (not at all) to 4 (very much) such that a higher response indicates worse symptoms. The mean of these responses is linearly transformed to a range of 0 (best) to 100 (worst). Change from baseline is calculated as the time point value - baseline value and a decrease from baseline indicates improvement in symptoms. A negative number indicates improvement in symptoms. (NCT00081289)
Timeframe: Baseline and completion of chemoradiation approximately 6-8 weeks from randomization

Interventionscore on a scale (Mean)
Neoadjuvant Chemoradiation With Irinotecan5.9
Neoadjuvant Chemoradiation With Oxaliplatin20.3

Change From Baseline in EORTC QLQ-CR38 Gastro-intestinal Symptom Score at Completion of Post-operative Chemotherapy

The gastro-intestinal (GI) symptom score is calculated from five symptom questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-CR38. The question responses range from 1 (not at all) to 4 (very much) such that a higher response indicates worse symptoms. The mean of these responses is linearly transformed to a range of 0 (best) to 100 (worst). Change from baseline is calculated as the time point value - baseline value and a decrease from baseline indicates improvement in symptoms. A negative number indicates improvement in symptoms. (NCT00081289)
Timeframe: Baseline and completion of post-operative chemotherapy approximately 32 to 40 weeks from randomization based on 18 weeks of post-operative chemotherapy

Interventionscore on a scale (Mean)
Neoadjuvant Chemoradiation With Irinotecan-1.5
Neoadjuvant Chemoradiation With Oxaliplatin3.9

Change From Baseline in EORTC QLQ-CR38 Gastro-intestinal Symptom Score at Two Years

The gastro-intestinal (GI) symptom score is calculated from five symptom questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-CR38. The question responses range from 1 (not at all) to 4 (very much) such that a higher response indicates worse symptoms. The mean of these responses is linearly transformed to a range of 0 (best) to 100 (worst). Change from baseline is calculated as the time point value - baseline value and a decrease from baseline indicates improvement in symptoms. A negative number indicates improvement in symptoms. (NCT00081289)
Timeframe: Baseline and two years

Interventionscore on a scale (Mean)
Neoadjuvant Chemoradiation With Irinotecan0.4
Neoadjuvant Chemoradiation With Oxaliplatin6.7

Change From Baseline in QLQ-C30 Global Health Status Score at Completion of Chemoradiation

"Global Health Status is calculated from two questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-C30. The question responses range from 1 very poor to 7 excellent such that a higher response indicates better quality of life (QOL). The mean of these responses is linearly transformed to a range of 0 (worst) to 100 (best). Change from baseline is calculated as the time point value - baseline value and a decrease from baseline indicates decline in quality of life. A positive number indicates improvement in QOL." (NCT00081289)
Timeframe: Baseline and completion of chemoradiation, approximately 6-8 weeks from randomization

Interventionscore on a scale (Mean)
Neoadjuvant Chemoradiation With Irinotecan-10.3
Neoadjuvant Chemoradiation With Oxaliplatin-12.2

Change From Baseline in QLQ-C30 Global Health Status Score at Completion of Post-operative Chemotherapy

"Global Health Status is calculated from two questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-C30. The question responses range from 1 very poor to 7 excellent such that a higher response indicates better quality of life (QOL). The mean of these responses is linearly transformed to a range of 0 (worst) to 100 (best). Change from baseline is calculated as the time point value - baseline value and a decrease from baseline indicates decline in quality of life. A positive number indicates improvement in QOL." (NCT00081289)
Timeframe: Baseline and completion of post-operative chemotherapy approximately 32 to 40 weeks from randomization based on 18 weeks of post-operative chemotherapy

Interventionscore on a scale (Mean)
Neoadjuvant Chemoradiation With Irinotecan-12.5
Neoadjuvant Chemoradiation With Oxaliplatin-7.1

Change From Baseline in QLQ-C30 Global Health Status Score at Two Years

"Global Health Status is calculated from two questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-C30. The question responses range from 1 very poor to 7 excellent such that a higher response indicates better quality of life (QOL). The mean of these responses is linearly transformed to a range of 0 (worst) to 100 (best). Change from baseline is calculated as the time point value - baseline value and a decrease from baseline indicates decline in quality of life. A negative number indicates improvement in symptoms." (NCT00081289)
Timeframe: Baseline and two years

Interventionscore on a scale (Mean)
Neoadjuvant Chemoradiation With Irinotecan-6.8
Neoadjuvant Chemoradiation With Oxaliplatin-1.3

Disease-free Survival Rate at 4 Years

Disease-free survival time is defined as time from randomization to date of local-regional failure, the appearance of distant metastases, the appearance of a second primary failure, or date of death from any cause/ Disease-free survival rates are estimated by the Kaplan-Meier method. Patients last known to be alive without failure are censored at the date of last contact. (NCT00081289)
Timeframe: From randomization to four years

Interventionpercentage of participants (Number)
Neoadjuvant Chemoradiation With Irinotecan68
Neoadjuvant Chemoradiation With Oxaliplatin62

Distant Failure Rate at 4 Years

Time to distant failure is defined as time from randomization to date of the appearance of distant metastases, last known follow-up (censored), or death without distant failure (competing risk). Distant failure rates are estimated by the cumulative incidence method. (NCT00081289)
Timeframe: From randomization to four years

Interventionpercentage of participants (Number)
Neoadjuvant Chemoradiation With Irinotecan24
Neoadjuvant Chemoradiation With Oxaliplatin30

Local-regional Failure Rate at 4 Years

Local-regional failure is defined as any of the following: no clinical complete response (cCR) in the primary site and/or nodes at any time after treatment completion (persistence), recurrence and/or progression in the primary site and/or nodes after cCR, and nonprotocol surgery to the primary site after cCR. Time to local-regional failure is defined as time from randomization to date of failure, last known follow-up (censored), or death without local-regional failure (competing risk). Local-regional failure rates are estimated by the cumulative incidence method. (NCT00081289)
Timeframe: From randomization to four years

Interventionpercentage of participants (Number)
Neoadjuvant Chemoradiation With Irinotecan16
Neoadjuvant Chemoradiation With Oxaliplatin18

Pathologic Complete Response Rate

"A pathologic complete response (pCR) was defined as no evidence of residual cancer histologically; disease progression or death before surgery was considered less than pCR (even without surgical specimen). All cases were reviewed by the study's surgical oncology co-chair for the determination of pCR.~Each arm was first analyzed alone. If the arm had 9 or more pCRs in 48 evaluable pts, then the null hypothesis (H0) of 10% pCR rate would be rejected in favor of the alternative hypothesis of 25%, providing 90% power with a two-sided 10% type I error rate. If both arms reject H0, then statistical selection theory would be used to choose the arm for further study in a phase III trial. If only one arm has acceptable pCR rate, then that arm would be pursued in a phase III trial." (NCT00081289)
Timeframe: After protocol surgery, approximately 10-16 weeks from randomization based on surgery occurring 4-8 weeks after chemoradiation

Interventionpercentage of participants (Number)
Neoadjuvant Chemoradiation With Irinotecan10.4
Neoadjuvant Chemoradiation With Oxaliplatin20.8

Second Primary Rate at 4 Years

Time to second primary is defined as time from randomization to date of the appearance of a second primary cancer, last known follow-up (censored), or death without second primary (competing risk). Second primary rates are estimated by the cumulative incidence method. (NCT00081289)
Timeframe: From randomization to four years

Interventionpercentage of participants (Number)
Neoadjuvant Chemoradiation With Irinotecan2
Neoadjuvant Chemoradiation With Oxaliplatin6

Survival Rate at 4 Years

Survival time is defined as time from registration/randomization to the date of death from any cause or last known follow-up (censored). Survival rates are estimated by the Kaplan-Meier method. (NCT00081289)
Timeframe: From randomization to four years

Interventionpercentage of participants (Number)
Neoadjuvant Chemoradiation With Irinotecan85
Neoadjuvant Chemoradiation With Oxaliplatin75

Number of Participants With Grade 3+ Treatment-related Adverse Events

Highest grade adverse event per subject were counted. Adverse events were graded using the Common Terminology Criteria for Adverse Events (CTCAE) v3.0. Grade refers to the severity of the AE. The CTCAE v3.0 assigns Grades 1 through 5 with unique clinical descriptions of severity for each AE based on this general guideline: Grade 1 Mild AE, Grade 2 Moderate AE, Grade 3 Severe AE, Grade 4 Life-threatening or disabling AE, Grade 5 Death related to AE. (NCT00081289)
Timeframe: From start of treatment to end of follow-up. Maximum follow-up is 5.2 years.

,
InterventionParticipants (Count of Participants)
HematologicNon-HematologicOverall
Neoadjuvant Chemoradiation With Irinotecan203238
Neoadjuvant Chemoradiation With Oxaliplatin192936

Number of Participants With Grade 3+ Treatment-related Adverse Events Postoperatively

Highest grade adverse event per subject were counted. Adverse events were graded using the Common Terminology Criteria for Adverse Events (CTCAE) v3.0. Grade refers to the severity of the AE. The CTCAE v3.0 assigns Grades 1 through 5 with unique clinical descriptions of severity for each AE based on this general guideline: Grade 1 Mild AE, Grade 2 Moderate AE, Grade 3 Severe AE, Grade 4 Life-threatening or disabling AE, Grade 5 Death related to AE. (NCT00081289)
Timeframe: From post-surgery to before chemotherapy (CT), or within 60 days of surgery if no postoperative CT. Approximately 10-16 weeks to 14-22 weeks from randomization based on CT starting 4-6 weeks after surgery.

,
InterventionParticipants (Count of Participants)
HematologicNon-HematologicOverall
Neoadjuvant Chemoradiation With Irinotecan199
Neoadjuvant Chemoradiation With Oxaliplatin3910

Number of Participants With Grade 3+ Treatment-related Adverse Events Preoperatively

Highest grade adverse event per subject were counted. Adverse events were graded using the Common Terminology Criteria for Adverse Events (CTCAE) v3.0. Grade refers to the severity of the AE. The CTCAE v3.0 assigns Grades 1 through 5 with unique clinical descriptions of severity for each AE based on this general guideline: Grade 1 Mild AE, Grade 2 Moderate AE, Grade 3 Severe AE, Grade 4 Life-threatening or disabling AE, Grade 5 Death related to AE. (NCT00081289)
Timeframe: From start of treatment to surgery, approximately 10-16 weeks from randomization based on surgery occurring 4-8 weeks after chemoradiation. If no surgery, then <= 90 days from start of treatment.

,
InterventionParticipants (Count of Participants)
HematologicNon-HematologicOverall
Neoadjuvant Chemoradiation With Irinotecan51114
Neoadjuvant Chemoradiation With Oxaliplatin21414

Disease-Free Survival (DFS), The Proportion of Patients Predicted to be Alive Without Evidence of Disease Recurrence 24 Months After Completion of Protocol Treatment

The Proportion of Patients Predicted to be Alive Without Evidence of Disease Recurrence 24 Months After Completion of Protocol Treatment (NCT00308516)
Timeframe: 24 months

Interventionpercentage of participants (Number)
Preoperative 5FU/Radiation/Bevacizumab85
Postoperative 5FU/Radiation/Bevacizumab97

Overall Survival (OS), the Length of Time, in Months, That Patients Were Alive From Their First Date of Protocol Treatment Until Death

Overall Survival (OS) is defined ad the Length of time, in months, that patients were alive from their first date of protocol treatment until death. (NCT00308516)
Timeframe: 24 months

Interventionmonths (Median)
Preoperative 5FU/Radiation/BevacizumabNA
Postoperative 5FU/Radiation/BevacizumabNA

Disease-Free Survival

The three year rate of Disease-Free Survival (NCT00216086)
Timeframe: 36 months

Interventionpercentage (Number)
Single Group Assignment75.5

Local and Distant Disease Recurrence Rates

To determine the rates of local and distant disease recurrence after treatment. (NCT00216086)
Timeframe: 36 months

Interventionpercentage of particpants (Number)
metastatic disease recurrencelocally recurrence
Single Group Assignment220

Pathological Complete Response (pCR) Rate

"· To determine the pathological response rate of preoperative chemotherapy with capecitabine and irinotecan followed by combined modality chemoradiation with capecitabine in patients with locally advanced rectal cancer.~Pathological response was defined in the protocol as the proportion of complete (pCR) and non-complete pathological response (pNCR) among all evaluable patients." (NCT00216086)
Timeframe: 36 months

Interventionpercentage of patients (Number)
pCRpNCR
Single Group Assignment3356

Dose Related Toxicity

dose related toxicity is defined as follows:1. WBC damage >= grade 3; granular cell decrease >= grade 3; hemoglobin >= grade 2; platelet >= grade 2;SGPT/SGOT elevation >= grade 2; ALP >= grade 2; GGT >= grade 2; Tbil >= grade 2;renal function damage: BUN/Cr elevation >= grade 2;Non-gradular cell decreased fever >= grade 2;nausea/vomiting >= grade 2; fatigue >= grade 3; weight loss >= grade 3;gastritis >= grade 3; dairrea >= grade 3; abdominal pain >= grade 3; pancreatitis >= grade 2; upper gastrointestinal bleeding >= grade 2;other toxic reaction >= grade 3;KPS < 50 during the treatment (NCT01268943)
Timeframe: up to 9 weeks

Interventionevent (Number)
1000mg1
1200mg0
1400mg0
1500mg3

Cumulative Incidence of grade3+ Bowel Perforation, Grade 3+ Bleeding (Ocurring Withing 1 Years) and grade4+ Nonhematologic Acute Adverse Events (Limited to Within 90 Days of Treatment Start)

(NCT00685763)
Timeframe: 1 year following the completion of radiation therapy

Interventionparticipants (Number)
Proton Radiation and Chemotherapy0

Number of Participants With Serious and Non-Serious Adverse Events

Here is the number of participants with serious and non-serious adverse events assessed by the Common Terminology Criteria for Adverse Events (CTCAE v4.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life-threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT01479348)
Timeframe: Date treatment consent signed to date off study, approximately 20 months and 12 days.

InterventionParticipants (Count of Participants)
1/Intravenous (IV) Tetrahydrouridine (THU)2

Frequency and Severity of Adverse Events Assessed by the Common Terminology Criteria for Adverse Events (CTCAE) v4.0

[F-18]-5-fluoro-2'-deoxycytidine (FdCyd) was administered intravenously with administration of tetrahydrouridine (THU) and the frequency and severity of adverse events was observed. A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life-threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. Grade 0 is normal, Grade 1 is mild, Grade 2 is moderate, Grade 3 is severe or medically significant but not immediately life-threatening, Grade 4 is life-threatening consequences, and Grade 5 is death related to adverse event. (NCT01479348)
Timeframe: Within 5 days after interventions

Interventionadverse events (Number)
Day 1 Adverse EventsDay 2, Grade 2 HypoalbuminemiaDay 2, Grade 3 AnemiaDay 3 Adverse EventsDay 4 Adverse EventsDay 5 Adverse Events
1/Intravenous (IV) Tetrahydrouridine (THU)011000

Radiation Dosimetry Estimates of 5-fluoro-2'-Deoxycytidine (FdCyd) in Humans

Radiation dosimetry was determined based on the first patients. This involved making region of interest measurements on the scan for each major organ and measuring the uptake. Using standard dosimetry software this is converted into mSv/MBq, a standard measure of dosimetry. The software is known as Organ Level INternal Dose Assessment/EXponential Modeling (OLINDA) and is commonly used to generate this kind of data. (NCT01479348)
Timeframe: 1 year

InterventionmSv/MBq (Mean)
AdrenalsBrainBreastsGallbladder wallLower large intestine wallSmall intestineStomach wallUpper large intestine wallHeart wallKidneysLiverLungsMuscleOvariesPancreasRed marrowOsteogenic cellsSkinSpleenTestesThymusThyroidUrinary bladder wallUterus
1/Intravenous (IV) Tetrahydrouridine (THU)1.838.171.034.052.522.131.902.041.105.266.021.821.161.571.631.141.718.651.691.031.128.237.961.63

Tumor to Background Ratios (TBRs) of Target Lesions at 4 Time Points After Injection

Participants were scanned by positron emission tomography (PET) and lesions were measured at 4 time points after injection. (NCT01479348)
Timeframe: 9 minutes, 32 minutes, 56 minutes and 2 hours after injection

InterventionTBR ratio (Number)
Pt 1 L. Parotid adenosquam. cell ca at 9 minPt 1 L. Parotid adenosquam. cell ca at 32 minPt 1 L. Parotid adenosquam. cell ca at 56 minPt 1 L. Parotid adenosquam. cell ca at 2 hrsPt 2 R. Parapharyngeal Spindle Cell Ca at 9 minPt 2 R. Parapharyngeal Spindle Cell Ca at 32 minPt 2 R. Parapharyngeal Spindle Cell Ca at 56 minPt 2 R. Parapharyngeal Spindle Cell Ca at 2 hrsPt 3 Non-small Cell Lung Ca at 9 minPt 3 Non-small Cell Lung Ca at 32 minPt 3 Non-small Cell Lung Ca at 56 minPt 3 Non-small Cell Lung Ca at 2 hrsPt 4 Non-small Cell Lung Ca at 9 minPt 4 Non-small Cell Lung Ca at 32 minPt 4 Non-small Cell Lung Ca at 56 minPt 4 Non-small Cell Lung Ca at 2 hrsPt 5 Hepatocellular Ca at 9 minPt 5 Hepatocellular Ca at 32 minPt 5 Hepatocellular Ca at 56 minPt 5 Hepatocellular Ca at 2 hrs
1/Intravenous (IV) Tetrahydrouridine (THU)1.41.51.51.61.91.71.71.61.41.41.51.72.42.11.62.0NANANANA

Reviews

228 reviews available for fluorouracil and Cancer of Rectum

ArticleYear
Oxaliplatin-based adjuvant chemotherapy rather than fluorouracil-based chemotherapy in rectal cancer is more efficient to decrease distant metastasis and increase survival after preoperative chemoradiotherapy and surgery: a meta-analysis.
    International journal of colorectal disease, 2022, Volume: 37, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-F

2022
Severe Gastrointestinal Disorder Due to Capecitabine Associated with Dihydropyrimidine Dehydrogenase Deficiency: A Case Report and Literature Review.
    Internal medicine (Tokyo, Japan), 2022, Aug-15, Volume: 61, Issue:16

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Dihydropyrimidine Dehydrogenase Deficiency; Fluoroura

2022
Adjuvant chemotherapy after neoadjuvant chemo-radiotherapy and surgery in locally advanced rectal cancer. A systematic review of literature with a meta-analysis of randomized clinical trials.
    Critical reviews in oncology/hematology, 2022, Volume: 172

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Fluoroura

2022
Efficacy and safety of aflibercept plus chemotherapy in metastatic colorectal cancer: A systematic review and PRISMA-Compliant single-arm Meta-Analysis of noncomparative clinical studies and randomized controlled trials.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2022
Is short-course radiotherapy and total neoadjuvant therapy the new standard of care in locally advanced rectal cancer? A sensitivity analysis of the RAPIDO clinical trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2022, Volume: 33, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Chemoradiotherapy; Chemotherapy, Adju

2022
Management of Rectal Cancer.
    Hematology/oncology clinics of North America, 2022, Volume: 36, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Fluoroura

2022
A Systematic Review of Conversion to Resectability in Unresectable Metastatic Colorectal Cancer Chemotherapy Trials.
    American journal of clinical oncology, 2022, 08-01, Volume: 45, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colonic Neopla

2022
[Impact of IMRT for neoadjuvant rectal cancer?]
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2022, Volume: 26, Issue:6-7

    Topics: Fluorouracil; Humans; Neoadjuvant Therapy; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulate

2022
Chemotherapy Duration for Various Indications in Colorectal Cancer: a Review.
    Current oncology reports, 2023, Volume: 25, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Fluorou

2023
A phase Ib/II trial of PEP503 (NBTXR3, radioenhancer) with radiotherapy and chemotherapy in patients with rectal cancer.
    Nanomedicine (London, England), 2023, Volume: 18, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials

2023
A systemic review and meta-analysis of Aflibercept plus FOLFIRI regimen as a second-line treatment for metastatic colorectal cancer: A PRISMA compliant pooled analysis of randomized controlled trials and single arm studies to assess efficacy and safety.
    Critical reviews in oncology/hematology, 2023, Volume: 188

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2023
Phase II biomarker identification study of anti-VEGF agents with FOLFIRI for pretreated metastatic colorectal cancer.
    Future oncology (London, England), 2023, Volume: 19, Issue:23

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers; Camptothecin; Clinical Tria

2023
Triplet-drug chemotherapy combined with anti-EGFR antibody as an effective therapy for patients with initially unresectable metastatic colorectal cancer: a meta-analysis.
    World journal of surgical oncology, 2023, Nov-18, Volume: 21, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Clinical Trials, Phase II as Topic; Colon

2023
Oxaliplatin-Induced Multiple Focal Nodular Hyperplasia Masquerading as Colorectal Liver Metastasis-Case Report and Review of Literature.
    Journal of gastrointestinal cancer, 2020, Volume: 51, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Digestive System S

2020
Adjuvant chemotherapy in rectal cancer: state of the art and future perspectives.
    Current opinion in oncology, 2020, Volume: 32, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clinical Trials, Phase II as

2020
Total neoadjuvant therapy for rectal cancer: Making sense of the results from the RAPIDO and PRODIGE 23 trials.
    Cancer treatment reviews, 2021, Volume: 96

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Clinical Trials, Ph

2021
Total neoadjuvant therapy for rectal cancer: Making sense of the results from the RAPIDO and PRODIGE 23 trials.
    Cancer treatment reviews, 2021, Volume: 96

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Clinical Trials, Ph

2021
Total neoadjuvant therapy for rectal cancer: Making sense of the results from the RAPIDO and PRODIGE 23 trials.
    Cancer treatment reviews, 2021, Volume: 96

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Clinical Trials, Ph

2021
Total neoadjuvant therapy for rectal cancer: Making sense of the results from the RAPIDO and PRODIGE 23 trials.
    Cancer treatment reviews, 2021, Volume: 96

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Clinical Trials, Ph

2021
Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations.
    ESMO open, 2021, Volume: 6, Issue:4

    Topics: Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradiotherapy; Fluorouracil; Humans; Rectal Neoplasms

2021
[Neoadjuvant treatment for rectal cancer].
    Bulletin du cancer, 2021, Volume: 108, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Clinical

2021
Meta-analysis of oxaliplatin-based versus fluorouracil-based neoadjuvant chemoradiotherapy and adjuvant chemotherapy for locally advanced rectal cancer.
    Oncotarget, 2017, May-23, Volume: 8, Issue:21

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans

2017
Evaluating the addition of oxaliplatin to single agent fluoropyrimidine in the treatment of locally advanced rectal cancer: a systematic review and meta-analysis.
    Expert review of anticancer therapy, 2017, Volume: 17, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Free Survival; Fl

2017
Randomized Clinical Trials in Colon and Rectal Cancer.
    Surgical oncology clinics of North America, 2017, Volume: 26, Issue:4

    Topics: Chemotherapy, Adjuvant; Colonic Neoplasms; Fluorouracil; Humans; Neoadjuvant Therapy; Randomized Con

2017
The Selective Use of Radiation Therapy in Rectal Cancer Patients.
    Current oncology reports, 2018, 04-11, Volume: 20, Issue:6

    Topics: Chemoradiotherapy; Combined Modality Therapy; Fluorouracil; Humans; Neoplasm Recurrence, Local; Neop

2018
Systematic review of treatment intensification using novel agents for chemoradiotherapy in rectal cancer.
    The British journal of surgery, 2018, Volume: 105, Issue:12

    Topics: Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Proto

2018
Potential predictive biomarkers in locally advanced rectal cancer treated with preoperative chemo-radiotherapy.
    Acta bio-medica : Atenei Parmensis, 2018, 12-17, Volume: 89, Issue:9-S

    Topics: Antimetabolites, Antineoplastic; Biomarkers; Biomarkers, Tumor; Chemoradiotherapy; Fluorouracil; Gen

2018
[Acute Kidney Injury in a Patient with Diarrhea and Vomiting Undergoing Chemotherapy for Colorectal Cancer].
    Rinsho byori. The Japanese journal of clinical pathology, 2016, Volume: 64, Issue:5

    Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Diarrhea; Fluoroura

2016
Capecitabine versus 5-fluorouracil in neoadjuvant chemoradiotherapy of locally advanced rectal cancer: A meta-analysis.
    Medicine, 2019, Volume: 98, Issue:17

    Topics: Anal Canal; Capecitabine; Chemoradiotherapy, Adjuvant; Clinical Studies as Topic; Fluorouracil; Huma

2019
Optimizing neoadjuvant therapy for rectal cancer with oxaliplatin.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2013, Mar-01, Volume: 11, Issue:3

    Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Clinical Trials as Topic

2013
Radiochemotherapy in rectal cancer: the role of oxaliplatin.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2003, Volume: 5 Suppl 3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Dige

2003
Concurrent chemoradiotherapy for squamous cell carcinoma of the rectum.
    Hepato-gastroenterology, 2013, Volume: 60, Issue:123

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcin

2013
[A case of metastatic colorectal cancer with icterus due to multiple liver metastases treated effectively by FOLFOX plus bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:8

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Fata

2013
Postoperative 5-FU based radiochemotherapy in rectal cancer: retrospective long term results and prognostic factors of a pooled analysis on 1,338 patients.
    Anticancer research, 2013, Volume: 33, Issue:10

    Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Fluorouracil; Humans; Kap

2013
[Radiotherapy-associated morbidity and mortality in rectal surgery].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2013, Volume: 84, Issue:11

    Topics: Antineoplastic Agents; Combined Modality Therapy; Fluorouracil; Guideline Adherence; Humans; Infusio

2013
[Advances in new chemotherapeutic drugs for preoperative chemoradiation of locally advanced rectal cancer].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2014, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Fluorourac

2014
[Penile metastasis from rectal carcinoma: a case report and literature review].
    Zhonghua nan ke xue = National journal of andrology, 2014, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluoroura

2014
[Disappearance of a gastric lesion following modified FOLFOX6 chemotherapy in a patient with metastatic colorectal cancer: a case report and literature review].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2014, Volume: 111, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Ma

2014
Extensive bowel necrosis related to bevacizumab in metastatic rectal cancer patient: a case report and review of literature.
    Japanese journal of clinical oncology, 2015, Volume: 45, Issue:3

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemothera

2015
Review on adjuvant chemotherapy for rectal cancer - why do treatment guidelines differ so much?
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-

2015
Postoperative chemotherapy in patients with rectal cancer receiving preoperative radio(chemo)therapy: A meta-analysis of randomized trials comparing surgery ± a fluoropyrimidine and surgery + a fluoropyrimidine ± oxaliplatin.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2015, Volume: 41, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Combined Modality T

2015
Second-Line Therapy for Endometrial Cancer: The Need for Better Options.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Nov-01, Volume: 33, Issue:31

    Topics: Adenocarcinoma; Amines; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Clinical Trials

2015
[A CASE OF SOLITARY ADRENAL TUMOR METASTASIZED FROM RECTAL CANCER].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2015, Volume: 106, Issue:3

    Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Adrenalectomy; Aged; Antineoplastic Combined Chemotherapy P

2015
Adjuvant Chemotherapy in Rectal Cancer after Chemoradiotherapy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2016, Volume: 28, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Disease-Free Survival;

2016
[A Case of Pathologically Complete Response of a Rectal Cancer after Preoperative Treatment with mFOLFOX6 and Radiation Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluoroura

2015
Oxaliplatin/fluorouracil-based adjuvant chemotherapy for locally advanced rectal cancer after neoadjuvant chemoradiotherapy and surgery: a systematic review and meta-analysis of randomized controlled trials.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2016, Volume: 18, Issue:8

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; D

2016
Fluorouracil-based neoadjuvant chemoradiotherapy with or without oxaliplatin for treatment of locally advanced rectal cancer: An updated systematic review and meta-analysis.
    Oncotarget, 2016, Jul-19, Volume: 7, Issue:29

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Fluorouracil; Humans; N

2016
[Rectal squamous cell carcinoma treatment: Retrospective experience in two French university hospitals, review and proposals].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2016, Volume: 20, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcin

2016
Synchronous quintuple primary gastrointestinal tract malignancies: Case report.
    World journal of gastroenterology, 2017, Jan-07, Volume: 23, Issue:1

    Topics: Adenocarcinoma, Mucinous; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cancer

2017
Comparison of 5-FU-based and Capecitabine-based Neoadjuvant Chemoradiotherapy in Patients With Rectal Cancer: A Meta-analysis.
    Clinical colorectal cancer, 2017, Volume: 16, Issue:3

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherap

2017
Capecitabine-induced oromandibular dystonia: a case report and literature review.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:6

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Asian People; Brain Stem; Capecitabine; Deoxycytidi

2008
Neoadjuvant chemoradiation for rectal cancer: is more better?
    Oncology (Williston Park, N.Y.), 2008, Volume: 22, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2008
Chemotherapy in addition to preoperative radiotherapy in locally advanced rectal cancer - a systematic overview.
    Reviews on recent clinical trials, 2008, Volume: 3, Issue:3

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Evidence-Based Medicine; Fluorouracil; H

2008
[Advance in preoperative radiochemotherapy for resectable rectal cancer].
    Ai zheng = Aizheng = Chinese journal of cancer, 2008, Volume: 27, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptotic Protease-Activating Factor 1; Carcinoembry

2008
The role of capecitabine in the management of tumors of the digestive system.
    Reviews on recent clinical trials, 2009, Volume: 4, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms

2009
The multidisciplinary management of rectal cancer.
    The Surgical clinics of North America, 2009, Volume: 89, Issue:1

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Diagnostic Imaging; Digestive System Surgic

2009
[Neoadjuvant radiochemotherapy for rectal cancer].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2009, Volume: 80, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dose Fractionation, Radia

2009
[Possibilities of resistance prediction to neoadjuvant concomitant chemoradiotherapy in the treatment algorithm of patients with rectal carcinoma].
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2008, Volume: 21, Issue:6

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Capecitabine; Chemotherapy, Adju

2008
Limitation of surgical radicality in rectal cancer responding to neoadjuvant therapy.
    Onkologie, 2009, Volume: 32, Issue:5

    Topics: Antineoplastic Agents; Fluorouracil; Germany; Neoadjuvant Therapy; Practice Patterns, Physicians'; R

2009
Efficacy and safety of bevacizumab plus capecitabine and irinotecan regimen for metastatic colorectal cancer.
    Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Ant

2010
Preoperative radiotherapy of advanced rectal cancer with capecitabine and oxaliplatin with or without cetuximab: A pooled analysis of three prospective phase I-II trials.
    International journal of radiation oncology, biology, physics, 2010, Oct-01, Volume: 78, Issue:2

    Topics: Age Factors; Analysis of Variance; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antine

2010
Cetuximab and chemoradiation for rectal cancer--is the water getting muddy?
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:3

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined C

2010
Does adjuvant fluoropyrimidine-based chemotherapy provide a benefit for patients with resected rectal cancer who have already received neoadjuvant radiochemotherapy? A systematic review of randomised trials.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; F

2010
[A case of poorly differentiated adenocarcinoma of the rectum with disseminated carcinomatosis of the bone marrow successfully treated with mFOLFOX-6/bevacizumab].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2010, Volume: 107, Issue:7

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined C

2010
[Difference of colon cancer and rectal cancer-from the view of an oncological physician].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2010, Volume: 32, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Chromosomal In

2010
Induction chemotherapy before chemoradiotherapy and surgery for locally advanced rectal cancer : is it time for a randomized phase III trial?
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2010, Volume: 186, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clinical Trials, Phase II as

2010
Evolution of 5-fluorouracil-based chemoradiation in the management of rectal cancer.
    Anti-cancer drugs, 2011, Volume: 22, Issue:4

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Neoadjuvant Ther

2011
[A case of interstitial lung diseases in patient treated with oxaliplatin, 5-fluorouracil and leucovorin (FOLFOX)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Lung Disease

2011
[Severe gastric and duodenal ulcer after chemotherapy of mFOLFOX6 and bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:3

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2011
Beyond 5-fluorouracil: the emerging role of newer chemotherapeutics and targeted agents with radiation therapy.
    Seminars in radiation oncology, 2011, Volume: 21, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clini

2011
Symptomatic 5-fluorouracil-induced sinus bradycardia.
    Internal medicine journal, 2011, Volume: 41, Issue:7

    Topics: Antimetabolites, Antineoplastic; Arrhythmia, Sinus; Bradycardia; Fluorouracil; Humans; Infusions, In

2011
[Preoperative radiochemotherapy for rectal cancer: forecasting the next steps through ongoing and forthcoming studies].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2011, Volume: 15, Issue:6-7

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineop

2011
[Rectal cancer: current status of multimodal therapy--when and how?].
    Zentralblatt fur Chirurgie, 2011, Volume: 136, Issue:4

    Topics: Algorithms; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Chemoradiotherapy, Adjuvant; Combine

2011
[Chemotherapy and rectal cancer].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2011, Volume: 15, Issue:6-7

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineop

2011
Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer.
    The British journal of surgery, 2012, Volume: 99, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Female; F

2012
Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer.
    The British journal of surgery, 2012, Volume: 99, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Female; F

2012
Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer.
    The British journal of surgery, 2012, Volume: 99, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Female; F

2012
Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer.
    The British journal of surgery, 2012, Volume: 99, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Female; F

2012
Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer.
    The British journal of surgery, 2012, Volume: 99, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Female; F

2012
Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer.
    The British journal of surgery, 2012, Volume: 99, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Female; F

2012
Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer.
    The British journal of surgery, 2012, Volume: 99, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Female; F

2012
Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer.
    The British journal of surgery, 2012, Volume: 99, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Female; F

2012
Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer.
    The British journal of surgery, 2012, Volume: 99, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Female; F

2012
Postoperative adjuvant chemotherapy in rectal cancer operated for cure.
    The Cochrane database of systematic reviews, 2012, Mar-14, Issue:3

    Topics: Antineoplastic Agents; Biological Products; Camptothecin; Chemotherapy, Adjuvant; Fluorouracil; Huma

2012
Rectal cancer: state of the art in 2012.
    Current opinion in oncology, 2012, Volume: 24, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Combined Modality Therapy; Fluoro

2012
What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Pha

2012
What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Pha

2012
What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Pha

2012
What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Pha

2012
What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Pha

2012
What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Pha

2012
What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Pha

2012
What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Pha

2012
What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Pha

2012
The role of capecitabine in locally advanced rectal cancer treatment: an update.
    Drugs, 2012, May-28, Volume: 72, Issue:8

    Topics: Antineoplastic Agents; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Fluorouracil; Humans;

2012
[FOLFIRI with bevacizumab chemotherapy for a patient with recurrence of rectal cancer under haemodialysis for chronic renal failure].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camp

2012
Addisonian crisis secondary to bilateral adrenal metastases in rectal carcinoma: report of a rare case and literature review.
    Journal of gastrointestinal cancer, 2013, Volume: 44, Issue:2

    Topics: Addison Disease; Adenocarcinoma; Adrenal Gland Neoplasms; Antimetabolites, Antineoplastic; Capecitab

2013
Oxaliplatin-induced thrombotic thrombocytopenic purpura: case report and literature review.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Nov-01, Volume: 30, Issue:31

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protoc

2012
Short term results of neoadjuvant chemoradiotherapy with fluoropyrimidine alone or in combination with oxaliplatin in locally advanced rectal cancer: a meta analysis.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Fluo

2013
Neoadjuvant short- or long-term radio(chemo)therapy for rectal cancer: how and who should be treated?
    Digestive diseases (Basel, Switzerland), 2012, Volume: 30 Suppl 2

    Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Dose Fractionation, Radiation; Fluorou

2012
Combined-modality therapy for rectal cancer using irinotecan.
    Oncology (Williston Park, N.Y.), 2002, Volume: 16, Issue:5 Suppl 5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials as Top

2002
Future directions in adjuvant therapy for rectal cancer.
    Oncology (Williston Park, N.Y.), 2002, Volume: 16, Issue:5 Suppl 5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clinical Trials as Topic; Co

2002
[Adjuvant and neoadjuvant radiochemotherapy of rectal carcinoma].
    Praxis, 2002, Sep-11, Volume: 91, Issue:37

    Topics: Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Humans; N

2002
Chemotherapy for colorectal cancer.
    Hematology/oncology clinics of North America, 2002, Volume: 16, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colon

2002
Chemoradiation with novel agents for rectal cancer.
    Clinical colorectal cancer, 2002, Volume: 2, Issue:1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Camptothecin; Cetuximab; Chemotherapy, Ad

2002
[Progress in adjuvant therapy for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug A

2002
Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.
    Journal of surgical oncology, 2003, Volume: 82, Issue:2

    Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Bone Morphogenetic Protein 2; Bone Morphogen

2003
Adjuvant radiation therapy of patients with rectal cancer.
    Clinical colorectal cancer, 2003, Volume: 2, Issue:4

    Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Colectomy; Combined Modality Therapy; Dos

2003
[Adjuvant therapy of rectal cancer].
    La Tunisie medicale, 2003, Volume: 81, Issue:2

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Fluorour

2003
[Radiotherapy for locally relapsed rectal cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Camptothecin; Combined Modality Thera

2003
Chemotherapeutic and biologic agents as radiosensitizers in rectal cancer.
    Seminars in radiation oncology, 2003, Volume: 13, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Campt

2003
Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Feb-01, Volume: 22, Issue:3

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2004
The development and application of functional nuclear magnetic resonance to in vivo therapeutic anticancer research: 2002 Sir Godfrey Hounsfield lecture delivered at the President's Day, Manchester.
    The British journal of radiology, 2004, Volume: 77, Issue:916

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Biliary Tract; Biomarkers; Fluorouracil; Forecastin

2004
Adjuvant therapy for rectal cancer in the elderly.
    Drugs & aging, 2004, Volume: 21, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cli

2004
Combined-modality therapy of rectal cancer with irinotecan-based regimens.
    Oncology (Williston Park, N.Y.), 2004, Volume: 18, Issue:14 Suppl 1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemothe

2004
Combined modality treatment for rectal cancer.
    Seminars in oncology, 2005, Volume: 32, Issue:1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Com

2005
Commentary on Wang et al., "Pre-operative chemotherapy with oral tegafur-uracil and leucovorin for rectal cancer" (J Surg Oncol 89: 256-263).
    Journal of surgical oncology, 2005, May-01, Volume: 90, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Combined Modalit

2005
An overview of approaches to adjuvant therapy for colorectal cancer in the United States.
    Clinical colorectal cancer, 2005, Volume: 5 Suppl 1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Com

2005
Pathological complete response following pre-operative chemoradiotherapy in rectal cancer: analysis of phase II/III trials.
    The British journal of radiology, 2005, Volume: 78, Issue:934

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Clinical Trials,

2005
[Management of rectal cancer in pregnant women].
    Bulletin du cancer, 2005, Volume: 92, Issue:11

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Case Management; Cesarean Section; Chemotherapy, Adjuv

2005
The integration of oral capecitabine into chemoradiation regimens for locally advanced rectal cancer: how successful have we been?
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:3

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol

2006
Preoperative and adjuvant treatment of localized rectal cancer.
    Current oncology reports, 2006, Volume: 8, Issue:3

    Topics: Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Fluorouracil; Huma

2006
[FOLFIRI regimen for metastatic or recurrent colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials, Phase III as Topic; C

2006
Intensified neoadjuvant radiochemotherapy for locally advanced rectal cancer: a review.
    International journal of colorectal disease, 2007, Volume: 22, Issue:5

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C

2007
[Progress in the treatment of gastrointestinal cancers due to introduction of neoadjuvant concept].
    Magyar sebeszet, 2006, Volume: 59, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Ci

2006
[Adjuvant chemotherapy for colorectal cancer in Japan-current state and problem areas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colonic Neopla

2007
Integration of novel agents into combined-modality treatment for rectal cancer patients.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2007, Volume: 183, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemotherapy, Adjuvant;

2007
Radiotherapy for localized rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18 Suppl 9

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothe

2007
[Bevacizumab (Avastin)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:8

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C

2007
[Preoperative treatments of rectal cancers].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2007, Volume: 11, Issue:6-7

    Topics: Antimetabolites, Antineoplastic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as T

2007
Capecitabine vs continuous infusion 5-FU in neoadjuvant treatment of rectal cancer. A retrospective review.
    International journal of colorectal disease, 2008, Volume: 23, Issue:2

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycy

2008
Total mesorectal excision and management of rectal cancer.
    Expert review of anticancer therapy, 2007, Volume: 7, Issue:10

    Topics: Adenocarcinoma; Anastomosis, Surgical; Antineoplastic Agents; Combined Modality Therapy; Disease Man

2007
Combined-modality therapy for rectal cancer: future prospects.
    Clinical colorectal cancer, 2007, Volume: 6, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Com

2007
Capecitabine and radiotherapy as neoadjuvant treatment for rectal cancer.
    American journal of clinical oncology, 2007, Volume: 30, Issue:6

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant

2007
Current options for the management of rectal cancer.
    Current treatment options in oncology, 2007, Volume: 8, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine;

2007
Chemo-radiotherapy: an alternative to surgery for squamous cell carcinoma of the rectum--report of six patients and literature review.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2009, Volume: 11, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co

2009
The use of capecitabine in the combined-modality therapy for rectal cancer.
    Clinical colorectal cancer, 2008, Volume: 7, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemo

2008
Treatment of the carcinoid tumor and the malignant carcinoid syndrome.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Ap

1983
Chemotherapy in alimentary tract malignomas.
    Hepato-gastroenterology, 1981, Volume: 28, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxor

1981
Intraarterial hepatic infusion chemotherapy in metastatic liver cancer.
    Seminars in oncology, 1983, Volume: 10, Issue:2

    Topics: Antineoplastic Agents; Colonic Neoplasms; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusio

1983
Comparison of systemic chemotherapy with hepatic arterial infusion in metastatic colorectal carcinoma.
    Seminars in oncology, 1983, Volume: 10, Issue:2

    Topics: Antineoplastic Agents; Catheterization; Colonic Neoplasms; Drug Therapy, Combination; Floxuridine; F

1983
Hepatic arterial chemotherapy for colorectal cancer metastatic to the liver.
    Annals of internal medicine, 1984, Volume: 100, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridin

1984
The systemic chemotherapy of hepatic metastases.
    Seminars in oncology, 1983, Volume: 10, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; D

1983
An analysis of chemotherapy for colorectal carcinoma.
    Journal of surgical oncology, 1984, Volume: 25, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Combine

1984
[Treatment of metastatic liver tumors].
    Voprosy onkologii, 1984, Volume: 30, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Emboli

1984
Systemic adjuvant therapy with BCG versus BCG + 5FU in colorectal cancer Dukes' Class C: updated critical analysis.
    Progress in experimental tumor research, 1980, Volume: 25

    Topics: Aged; BCG Vaccine; Carcinoembryonic Antigen; Clinical Trials as Topic; Colonic Neoplasms; Female; Fl

1980
Systemic chemotherapy for advanced gastrointestinal cancer.
    Southern medical journal, 1980, Volume: 73, Issue:8

    Topics: Antineoplastic Agents; Apudoma; Biliary Tract Neoplasms; Colonic Neoplasms; Drug Therapy, Combinatio

1980
Studies on the treatment and prevention of colorectal liver metastases.
    Annals of the Royal College of Surgeons of England, 1981, Volume: 63, Issue:4

    Topics: Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Fluorouracil; Hemodynamics; Humans; Liv

1981
Large bowel cancer: an overview.
    The Australian and New Zealand journal of surgery, 1982, Volume: 52, Issue:1

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Femal

1982
Possibilities and limitations of the cytostatic treatment of gastrointestinal carcinoma.
    Hepato-gastroenterology, 1982, Volume: 29, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Es

1982
[Choice of treatment in rectal cancer. Consensus Conference, Chamber of Commerce and Industry, Paris, December 1-2, 1994].
    Annales de gastroenterologie et d'hepatologie, 1995, Volume: 31, Issue:4

    Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Prot

1995
Adjuvant chemotherapy for colon and rectal cancer.
    Seminars in oncology, 1995, Volume: 22, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Fluoroura

1995
Adjuvant radiation for rectal cancer: when and with what?
    Current opinion in general surgery, 1994

    Topics: Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Humans; R

1994
Role of adjuvant therapy in surgically resected colorectal carcinoma.
    Gastroenterology, 1995, Volume: 109, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined

1995
[Chemotherapy of metastasizing cancers of the colon and rectum].
    Annales de chirurgie, 1993, Volume: 47, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neopla

1993
Squamous cell carcinoma complicating idiopathic inflammatory bowel disease.
    Journal of surgical oncology, 1995, Volume: 59, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transiti

1995
[Developments up to now and current status of adjuvant chemo- and radiotherapy in colonic and rectal carcinoma].
    Langenbecks Archiv fur Chirurgie, 1994, Volume: 379, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colon

1994
[Adjuvant chemotherapy in cancers of the colon and rectum].
    La Revue du praticien, 1994, Dec-15, Volume: 44, Issue:20

    Topics: Chemotherapy, Adjuvant; Colonic Neoplasms; Fluorouracil; Humans; Levamisole; Rectal Neoplasms

1994
Adjuvant postoperative therapy of gastrointestinal malignancies.
    Oncology (Williston Park, N.Y.), 1994, Volume: 8, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined

1994
[Pre- and postoperative radiotherapy with and without chemotherapy in rectal cancer].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1994, Volume: 65, Issue:7

    Topics: Chemotherapy, Adjuvant; Combined Modality Therapy; Fluorouracil; Humans; Neoplasm Staging; Radiother

1994
[Adjuvant chemotherapy in rectal cancer].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1994, Volume: 65, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans

1994
[Adjuvant therapy in colorectal carcinomas].
    Deutsche medizinische Wochenschrift (1946), 1994, Dec-02, Volume: 119, Issue:48

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Fluoroura

1994
Preoperative combined modality treatment for rectal cancer.
    Oncology (Williston Park, N.Y.), 1994, Volume: 8, Issue:5

    Topics: Combined Modality Therapy; Fluorouracil; Humans; Leucovorin; Randomized Controlled Trials as Topic;

1994
The role of chemotherapy and adjuvant therapy in the management of colorectal cancer.
    Cancer, 1994, Oct-01, Volume: 74, Issue:7 Suppl

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemotherapy, Adjuvant; Colonic Neo

1994
Surgical adjuvant therapy for rectal cancer: present options.
    Diseases of the colon and rectum, 1994, Volume: 37, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

1994
Large scale trial for adjuvant treatment in high risk resected colorectal cancers. Rationale to test the combination of loco-regional and systemic chemotherapy and to compare l-leucovorin + 5-FU to levamisole + 5-FU.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1993, Volume: 4 Suppl 2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal N

1993
Primary linitis plastica of the rectum: report of four cases and review of the literature.
    Surgery today, 1996, Volume: 26, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1996
The role of adjuvant radiation therapy in the treatment of colorectal cancer.
    Hematology/oncology clinics of North America, 1997, Volume: 11, Issue:4

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colonic Neoplasms

1997
The role of adjuvant chemotherapy in the treatment of colorectal cancer.
    Hematology/oncology clinics of North America, 1997, Volume: 11, Issue:4

    Topics: Adjuvants, Immunologic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protoc

1997
[The current status of postoperative adjuvant chemotherapy for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:10

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colect

1997
Adjuvant therapy of colorectal cancer.
    Surgical oncology clinics of North America, 1997, Volume: 6, Issue:4

    Topics: Adjuvants, Immunologic; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Chemother

1997
Current and future directions in adjuvant combined-modality therapy of rectal cancer.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Combinations

1997
Results of local excision followed by postoperative radiation therapy for rectal cancer.
    Radiation oncology investigations, 1997, Volume: 5, Issue:5

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Fluorouracil; Humans; Neoplasm Recurrence,

1997
[Chemoradiation for rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autonomic Pathways; Drug Administration Schedule; Fl

1997
The role of radiation therapy in rectal cancer.
    Seminars in oncology, 1997, Volume: 24, Issue:5 Suppl 18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy;

1997
[Surgery and multidisciplinary treatment for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined

1998
Sphincter preservation in rectal cancer. Local excision followed by postoperative radiation therapy.
    Seminars in radiation oncology, 1998, Volume: 8, Issue:1

    Topics: Abdomen; Anal Canal; Antimetabolites, Antineoplastic; Carcinoma; Chemotherapy, Adjuvant; Colostomy;

1998
[Drug clinics. How I treat. II. Therapeutic approaches to metastatic colorectal cancer].
    Revue medicale de Liege, 1998, Volume: 53, Issue:6

    Topics: Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic

1998
Colorectal cancer: treatment of advanced disease.
    Cancer treatment reviews, 1998, Volume: 24, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoco

1998
Induction therapy for rectal carcinoma.
    Seminars in surgical oncology, 1998, Volume: 15, Issue:2

    Topics: Antidotes; Antimetabolites, Antineoplastic; Carcinoma; Combined Modality Therapy; Fluorouracil; Huma

1998
[Treatment of peritoneal carcinosis of colorectal origin].
    Journal de chirurgie, 1997, Volume: 134, Issue:5-6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemothe

1997
Management of hepatic metastases.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1999, Volume: 5, Issue:1

    Topics: Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil;

1999
Management of hepatic metastases.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1999, Volume: 5, Issue:1

    Topics: Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil;

1999
Management of hepatic metastases.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1999, Volume: 5, Issue:1

    Topics: Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil;

1999
Management of hepatic metastases.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1999, Volume: 5, Issue:1

    Topics: Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil;

1999
[Chemoradiotherapy in treatment of cancer of the anal canal].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 1998, Volume: 2, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemotherapy,

1998
Adjuvant therapy with oral fluoropyrimidines as main chemotherapeutic agents after curative resection for colorectal cancer: individual patient data meta-analysis of randomized trials.
    Japanese journal of clinical oncology, 1999, Volume: 29, Issue:2

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol

1999
Squamous-cell carcinoma of the colon responsive to combination chemotherapy: report of two cases and review of the literature.
    Diseases of the colon and rectum, 1999, Volume: 42, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisp

1999
[Continuous radiosensitizing chemotherapy].
    Pathologie-biologie, 1999, Volume: 47, Issue:3

    Topics: Antineoplastic Agents; Carboplatin; Carcinoma; Cisplatin; Clinical Trials as Topic; Combined Modalit

1999
[Treatment with cytostatic agents should be considered in colorectal cancer. It improves prognosis and quality of life].
    Lakartidningen, 1999, May-12, Volume: 96, Issue:19

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

1999
Which 5-fluorouracil regimen?--the great debate.
    Anti-cancer drugs, 1999, Volume: 10, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms;

1999
[Systemic palliative chemotherapy with 5-fluorouracil and leucovorin in disseminated colorectal cancer].
    Ugeskrift for laeger, 1999, Jun-21, Volume: 161, Issue:25

    Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols;

1999
[Rectal carcinoma. Optimizing treatment by neoadjuvant and adjuvant therapy?].
    Zentralblatt fur Chirurgie, 1999, Volume: 124, Issue:5

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Fluorouracil; Hu

1999
Adenosquamous carcinoma of the rectum showing endocrine-cell differentiation: report of a case.
    Diseases of the colon and rectum, 1999, Volume: 42, Issue:8

    Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Adenosquamous; Chemotherapy, Adjuvant; Fluorouraci

1999
Infusional chemoradiation for rectal and anal cancers.
    Oncology (Williston Park, N.Y.), 1999, Volume: 13, Issue:10 Suppl 5

    Topics: Anal Gland Neoplasms; Animals; Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluoroura

1999
[Is portal infusion chemotherapy uneffective for hepatic recurrence after resection for colorectal cancer?].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration

1999
[A case of liver metastases of rectal carcinoid successfully treated with hepatic arterial infusion of methotrexate and 5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Combined Modality Therapy; Dr

1999
Combined modality therapy of rectal cancers.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10 Suppl 6

    Topics: Antineoplastic Agents; Fluorouracil; Humans; Hyperthermia, Induced; Neoadjuvant Therapy; Neoplasm St

1999
[Radiotherapy and chemotherapy in the treatment of cancer of the rectum].
    Journal de chirurgie, 2000, Volume: 137, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Clinical Trials as Topic; Contro

2000
[Conceptual changes in cancer chemotherapy--biochemical modulation of 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:6

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms;

2000
[Capecitabine--a review of its antitumor activity and toxicity in clinical studies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabin

2000
Treatment of colorectal cancer.
    Annales chirurgiae et gynaecologiae, 2000, Volume: 89, Issue:3

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colectomy; Colonic Neoplasms; Colorectal Ne

2000
[New drugs in the treatment of advanced colorectal cancer].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Sep-30, Volume: 120, Issue:23

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoco

2000
Irinotecan in preoperative combined-modality therapy for locally advanced rectal cancer.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:12 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Fluorouracil; Humans; Irinotecan; Radi

2000
Rectal cancer: integrating oxaliplatin into chemoradiation studies.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:12 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Clinical Trials,

2000
Raltitrexed/5-fluorouracil-based combination chemotherapy regimens in anticancer therapy.
    Anti-cancer drugs, 2001, Volume: 12, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Fluo

2001
Chemoradiotherapy for rectal cancer--is there an optimal combination?
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:8

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Clinical Trials, Phas

2001
Improving chemoradiotherapy in rectal cancer.
    The oncologist, 2001, Volume: 6 Suppl 4

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Clinica

2001
Progress in treatment of cancer of the large bowel.
    The Journal of the Oklahoma State Medical Association, 1976, Volume: 69, Issue:8

    Topics: Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Follow-Up Studies; Humans; Intestinal Obstru

1976
[Current trends of complementary therapy in radical surgery of colo-rectal cancer].
    Minerva chirurgica, 1979, Mar-15, Volume: 34, Issue:5

    Topics: Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Humans; Immunotherapy; Postoperative Care; P

1979
Chemotherapy of colorectal carcinoma.
    Seminars in oncology, 1976, Volume: 3, Issue:4

    Topics: Administration, Oral; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Drug Administration Sche

1976
Management of gastrointestinal cancer.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluor

1977
Chemotherapy of gastrointestinal cancer.
    The New England journal of medicine, 1978, Nov-09, Volume: 299, Issue:19

    Topics: Apudoma; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Hum

1978
[Basic trends in the combined treatment of locally spread rectal cancer].
    Vestnik Akademii meditsinskikh nauk SSSR, 1979, Issue:8

    Topics: Fluorouracil; Humans; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Postoperati

1979
[Symposium on carcinoma of colon and rectum: 4. The role of adjuvant therapy with surgery in cancers of the colon and rectum].
    Canadian journal of surgery. Journal canadien de chirurgie, 1978, Volume: 21, Issue:1

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Immunosuppressive Agents; Neoplasm Metastasis; Nitrosourea

1978
Current protocol approaches in large bowel cancer.
    Seminars in oncology, 1976, Volume: 3, Issue:4

    Topics: Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Th

1976
Abdominal surgery (second of three parts).
    The New England journal of medicine, 1975, Oct-30, Volume: 293, Issue:18

    Topics: Abdomen; Acute Disease; Anus Diseases; Appendectomy; Appendicitis; Appendix; Carcinoembryonic Antige

1975
Combined radiotherapy and chemotherapy in the treatment of gastrointestinal malignancies.
    Seminars in oncology, 1992, Volume: 19, Issue:4 Suppl 11

    Topics: Combined Modality Therapy; Fluorouracil; Humans; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neo

1992
Accomplishments in surgical adjuvant therapy for large bowel cancer.
    Cancer, 1992, Sep-01, Volume: 70, Issue:5 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Drug T

1992
Chemotherapy of colorectal cancer.
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined

1992
Colorectal cancer. Recent developments and continuing controversies.
    Postgraduate medicine, 1992, Volume: 91, Issue:1

    Topics: Carcinoembryonic Antigen; Chemotherapy, Adjuvant; Colonic Neoplasms; Fluorouracil; Humans; Levamisol

1992
Unusual serpentine hyperpigmentation associated with 5-fluorouracil. Case report and review of cutaneous manifestations associated with systemic 5-fluorouracil.
    Journal of the American Academy of Dermatology, 1991, Volume: 25, Issue:5 Pt 2

    Topics: Adenocarcinoma; Aged; Drug Eruptions; Fluorouracil; Humans; Infusions, Intravenous; Male; Photosensi

1991
Role of radiation therapy in the treatment of carcinoma of the rectum.
    Journal of surgical oncology. Supplement, 1991, Volume: 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combined Modality Therapy; Fluorourac

1991
Chemotherapy of advanced cancer of the colon and rectum.
    Seminars in oncology, 1991, Volume: 18, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Fluorouracil; Huma

1991
Current treatment approaches in colorectal cancer.
    Seminars in oncology, 1991, Volume: 18, Issue:1 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Humans; Rectal Neop

1991
The role of immunotherapy in colorectal cancer.
    Seminars in oncology, 1991, Volume: 18, Issue:1 Suppl 1

    Topics: Antibodies, Monoclonal; Colonic Neoplasms; Fluorouracil; Humans; Immunologic Factors; Immunotherapy;

1991
Management of colorectal cancer.
    Comprehensive therapy, 1990, Volume: 16, Issue:11

    Topics: Adenocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Combined Modality Therapy; Fluorouracil; Hu

1990
Surgical therapy of early rectal carcinoma.
    Hematology/oncology clinics of North America, 1989, Volume: 3, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combined Modality Therapy; Fluorourac

1989
Anogenital papillomavirus infection and neoplasia in immunodeficient women.
    Obstetrics and gynecology clinics of North America, 1987, Volume: 14, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Combined Modality Therapy; Female; Fluorouracil; Genital Neoplas

1987
Treatment of colorectal hepatic metastases.
    Surgery, gynecology & obstetrics, 1985, Volume: 161, Issue:6

    Topics: Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; F

1985
Systemic cytostatic drug therapy in liver cancer.
    Annales chirurgiae et gynaecologiae. Supplementum, 1986, Volume: 200

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic;

1986
Colorectal cancer: surgical management of recurrent and metastatic disease.
    Journal of the National Medical Association, 1988, Volume: 80, Issue:5

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Liver Neoplasms; Neoplasm Recurrence, Local; Rectal Neoplas

1988
Hepatic artery ligation or embolization and locoregional chemotherapy of liver metastases from colorectal cancer.
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Emboli

1988
[Current studies of sequential methotrexate and 5-fluorouracil treatment in cancer chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Dru

1988
Evaluation and treatment of hepatic metastasis from colorectal cancer.
    Indiana medicine : the journal of the Indiana State Medical Association, 1988, Volume: 81, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Fluoro

1988
Surgical adjuvant therapy of rectal cancer.
    Seminars in oncology, 1988, Volume: 15, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Clinical Trials as Topic; Combined Modali

1988
Adjuvant therapy of colorectal cancer. Why we still don't know.
    JAMA, 1988, Jun-24, Volume: 259, Issue:24

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Neopla

1988
Role of chemotherapy in the treatment of colorectal carcinoma.
    Seminars in surgical oncology, 1987, Volume: 3, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined M

1987
Overview of current status and future direction of clinical trials with 5-fluorouracil in combination with folinic acid.
    Cancer treatment reports, 1987, Volume: 71, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Fluorou

1987
Biochemical modulation of fluorouracil therapy in advanced colorectal cancer.
    Annals of the Academy of Medicine, Singapore, 1987, Volume: 16, Issue:3

    Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Interactions; F

1987
[Chemotherapy of cancer of the large intestine].
    Sovetskaia meditsina, 1985, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms

1985
Optimal schedule for 5-fluorouracil chemotherapy. Intermittent bolus or continuous infusion?
    American journal of clinical oncology, 1985, Volume: 8, Issue:5

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusi

1985
Potentiation of antimetabolite action by alkylating agents.
    Advances in enzyme regulation, 1985, Volume: 24

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brea

1985
The prognosis and management of recurrent abdominal malignancies.
    Current problems in surgery, 1969

    Topics: Abdominal Neoplasms; Adolescent; Adult; Antineoplastic Agents; Bile Duct Neoplasms; Chemotherapy, Ca

1969
Dobbins WO 3d,+DOBBINS WO III: Rectal biopsy. A review of its diagnostic usefulness.
    Gastroenterology, 1968, Volume: 55, Issue:4

    Topics: Amyloidosis; Biopsy; Colitis, Ulcerative; Crohn Disease; Cystic Fibrosis; Cysts; Deficiency Diseases

1968
[Chemotherapy of cancer of the rectum and the colon].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1970, Nov-16, Volume: 25, Issue:46

    Topics: Antimetabolites; Colonic Neoplasms; Drug Synergism; Floxuridine; Fluorouracil; Humans; Injections, I

1970
Chemotherapy of residual disease in solid tumours.
    Revue europeenne d'etudes cliniques et biologiques. European journal of clinical and biological research, 1971, Volume: 16, Issue:2

    Topics: Colonic Neoplasms; Cyclophosphamide; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Lun

1971
Newer concepts in chemotherapy of cancer.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Breast Neoplasms; Colonic Neoplasms; Dysgerminoma; Female; Fluorouracil; Humans; Injections, Intra-A

1972
Obstacles to the improvement of radiotherapy of rectal cancer.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:12

    Topics: Adenocarcinoma; Animals; Cyclophosphamide; Fluorouracil; Humans; Laparotomy; Lymphography; Methods;

1973
Chemotherapy in colorectal cancer.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:12

    Topics: Carmustine; Chlorambucil; Colonic Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorourac

1973

Trials

773 trials available for fluorouracil and Cancer of Rectum

ArticleYear
Impact of body-mass index on treatment and outcome in locally advanced rectal cancer: A secondary, post-hoc analysis of the CAO/ARO/AIO-04 randomized phase III trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2021, Volume: 164

    Topics: Body Mass Index; Fluorouracil; Humans; Male; Neoadjuvant Therapy; Rectal Neoplasms; Treatment Outcom

2021
Postoperative Chemoradiotherapy With Capecitabine and Oxaliplatin vs Capecitabine for Stage II to III Rectal Cancer: A Randomized Clinical Trial.
    JAMA network open, 2021, 11-01, Volume: 4, Issue:11

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; China; Fema

2021
THUNDER 2: THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI guided radiotherapy.
    BMC cancer, 2022, Jan-15, Volume: 22, Issue:1

    Topics: Adult; Antineoplastic Agents; Capecitabine; Feasibility Studies; Female; Fluorouracil; Humans; Magne

2022
Impact of omitting fluorouracil from FOLFIRI plus bevacizumab as second-line chemotherapy for patients with metastatic colorectal cancer.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2023
Phase I Study of Lenvatinib and Capecitabine with External Radiation Therapy in Locally Advanced Rectal Adenocarcinoma.
    The oncologist, 2022, 08-05, Volume: 27, Issue:8

    Topics: Adenocarcinoma; Capecitabine; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm

2022
Impact of chronological age on efficacy and safety of fluoropyrimidine plus bevacizumab in older non-frail patients with metastatic colorectal cancer: a combined analysis of individual data from two phase II studies of patients aged >75 years.
    Japanese journal of clinical oncology, 2022, 07-08, Volume: 52, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colonic Neopla

2022
Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022, 08-10, Volume: 40, Issue:23

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Dis

2022
Quality of life in a randomized trial comparing two neoadjuvant regimens for locally advanced rectal cancer-INCAGI004.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fecal Incontinence;

2022
Predictive value of chromosome 18q11.2-q12.1 loss for benefit from bevacizumab in metastatic colorectal cancer: A post hoc analysis of the randomized phase III-trial AGITG-MAX.
    International journal of cancer, 2022, 10-01, Volume: 151, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Chromosome Deletion; Chromosomes; Colon

2022
Efficacy of FOLFIRI plus cetuximab vs FOLFIRI plus bevacizumab in 1st-line treatment of older patients with RAS wild-type metastatic colorectal cancer: an analysis of the randomised trial FIRE-3.
    British journal of cancer, 2022, Volume: 127, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colonic

2022
Germline Polymorphisms in Genes Involved in the Antioxidant System Predict the Efficacy of Cetuximab in Metastatic Colorectal Cancer Patients Enrolled in FIRE-3 Trial.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Bevacizumab; Camptothecin; Cetuximab;

2022
Multicenter, single-arm, phase II study of the continuous use of panitumumab in combination with FOLFIRI after FOLFOX for RAS wild-type metastatic colorectal cancer: Exploratory sequential examination of acquired mutations in circulating cell-free DNA.
    International journal of cancer, 2022, Dec-15, Volume: 151, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell-Free Nucleic Acids; Colonic Neopl

2022
[The TAILOR study establishes, in patients mCRC wt, the first line use of FOLFOX in combination with cetuximab].
    Recenti progressi in medicina, 2022, Volume: 113, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Colonic Neoplasms; Colorectal Neoplasms;

2022
Randomized phase II trial of FOLFIRI-panitumumab compared with FOLFIRI alone in patients with RAS wild-type circulating tumor DNA metastatic colorectal cancer beyond progression to first-line FOLFOX-panitumumab: the BEYOND study (GEMCAD 17-01).
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2022, Volume: 24, Issue:11

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Circulating Tu

2022
Population pharmacokinetic analyses of regorafenib and capecitabine in patients with locally advanced rectal cancer (SAKK 41/16 RECAP).
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Fluorouracil; Humans; Phenylurea Compo

2022
Efficacy and safety of dilpacimab (ABT-165) versus bevacizumab plus FOLFIRI in metastatic colorectal cancer: a phase II study.
    Future oncology (London, England), 2022, Volume: 18, Issue:27

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Co

2022
A Randomized, Open-Label, Multicenter, Phase 3 Study of High-Dose Vitamin C Plus FOLFOX ± Bevacizumab versus FOLFOX ± Bevacizumab in Unresectable Untreated Metastatic Colorectal Cancer (VITALITY Study).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 10-03, Volume: 28, Issue:19

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Bevacizumab; C

2022
First-line fluoropyrimidine plus bevacizumab followed by irinotecan-escalation versus initial fluoropyrimidine, irinotecan and bevacizumab in patients with metastatic colorectal cancer - Final survival and per-protocol analysis of the randomised XELAVIRI
    European journal of cancer (Oxford, England : 1990), 2022, Volume: 173

    Topics: Aged; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Co

2022
Standard diametric versus volumetric early tumor shrinkage as a predictor of survival in metastatic colorectal cancer: subgroup findings of the randomized, open-label phase III trial FIRE-3 / AIO KRK-0306.
    European radiology, 2023, Volume: 33, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colonic Neopla

2023
Neoadjuvant FOLFOXIRI prior to chemoradiotherapy for high-risk ("ugly") locally advanced rectal cancer: study protocol of a single-arm, multicentre, open-label, phase II trial (MEND-IT).
    BMC cancer, 2022, Sep-06, Volume: 22, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Clinical Trials, Ph

2022
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212).
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212).
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212).
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212).
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212).
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212).
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212).
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212).
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer: An analysis of the PanaMa trial (AIO KRK 0212).
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Napabucasin Plus FOLFIRI in Patients With Previously Treated Metastatic Colorectal Cancer: Results From the Open-Label, Randomized Phase III CanStem303C Study.
    Clinical colorectal cancer, 2023, Volume: 22, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms;

2023
Napabucasin Plus FOLFIRI in Patients With Previously Treated Metastatic Colorectal Cancer: Results From the Open-Label, Randomized Phase III CanStem303C Study.
    Clinical colorectal cancer, 2023, Volume: 22, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms;

2023
Napabucasin Plus FOLFIRI in Patients With Previously Treated Metastatic Colorectal Cancer: Results From the Open-Label, Randomized Phase III CanStem303C Study.
    Clinical colorectal cancer, 2023, Volume: 22, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms;

2023
Napabucasin Plus FOLFIRI in Patients With Previously Treated Metastatic Colorectal Cancer: Results From the Open-Label, Randomized Phase III CanStem303C Study.
    Clinical colorectal cancer, 2023, Volume: 22, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms;

2023
Efficacy and safety of folfiri plus aflibercept in second-line treatment of metastatic colorectal cancer: Real-life data from Turkish oncology group.
    Journal of cancer research and therapeutics, 2022, Volume: 18, Issue:12 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2022
Efficacy and safety of folfiri plus aflibercept in second-line treatment of metastatic colorectal cancer: Real-life data from Turkish oncology group.
    Journal of cancer research and therapeutics, 2022, Volume: 18, Issue:12 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2022
Efficacy and safety of folfiri plus aflibercept in second-line treatment of metastatic colorectal cancer: Real-life data from Turkish oncology group.
    Journal of cancer research and therapeutics, 2022, Volume: 18, Issue:12 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2022
Efficacy and safety of folfiri plus aflibercept in second-line treatment of metastatic colorectal cancer: Real-life data from Turkish oncology group.
    Journal of cancer research and therapeutics, 2022, Volume: 18, Issue:12 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2022
Comparison of short course radiotherapy with chemoradiotherapy for locally advanced rectal cancers in the elderly: A multicentre, randomised, non-blinded, phase 3 trial.
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 180

    Topics: Activities of Daily Living; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chem

2023
Tumor Response-speed Heterogeneity as a Novel Prognostic Factor in Patients With Metastatic Colorectal Cancer.
    American journal of clinical oncology, 2023, 02-01, Volume: 46, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Long-term results of a phase 2 study of neoadjuvant chemotherapy with molecularly targeted agents for locally advanced rectal cancer.
    International journal of clinical oncology, 2023, Volume: 28, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Follow-Up Studi

2023
NPY Methylated ctDNA is a Promising Biomarker for Treatment Response Monitoring in Metastatic Colorectal Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 05-01, Volume: 29, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers; Colonic Neoplasms; Colorect

2023
Trop-2 and Nectin-4 immunohistochemical expression in metastatic colorectal cancer: searching for the right population for drugs' development.
    British journal of cancer, 2023, Volume: 128, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2023
One-Week versus Two-Week Chemoradiotherapy Followed by Curative Surgery in Rectal Cancer: Long-Term Comparative Pooled Analysis of Two Prospective Multicenter Phase II Trials.
    Cancer research and treatment, 2023, Volume: 55, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fluorouracil; Human

2023
An Immune-Related Gene Expression Signature Predicts Benefit from Adding Atezolizumab to FOLFOXIRI plus Bevacizumab in Metastatic Colorectal Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 06-13, Volume: 29, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2023
Total neoadjuvant treatment to increase the clinical complete response rate for distal locally advanced rectal cancer (TESS): A study protocol of a prospective, open-label, multicenter, single-arm, phase 2 trial.
    Cancer medicine, 2023, Volume: 12, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Clinical Trials, Ph

2023
A phase Ib/II trial of PEP503 (NBTXR3, radioenhancer) with radiotherapy and chemotherapy in patients with rectal cancer.
    Nanomedicine (London, England), 2023, Volume: 18, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials

2023
Preoperative chemoradiotherapy using tegafur/uracil, oral leucovorin, and irinotecan (TEGAFIRI) followed by oxaliplatin-based chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: the study protocol for a phase II trial.
    BMC cancer, 2023, May-17, Volume: 23, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Phase II as Topi

2023
Patient-Reported Outcomes During and After Treatment for Locally Advanced Rectal Cancer in the PROSPECT Trial (Alliance N1048).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 07-20, Volume: 41, Issue:21

    Topics: Adult; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin;

2023
Preoperative Treatment of Locally Advanced Rectal Cancer.
    The New England journal of medicine, 2023, Jul-27, Volume: 389, Issue:4

    Topics: Adult; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy,

2023
Adverse events during first-line treatments for mCRC: The Toxicity over Time (ToxT) analysis of three randomised trials.
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 189

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2023
FOLFOXIRI Plus Cetuximab or Bevacizumab as First-Line Treatment of
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 09-01, Volume: 41, Issue:25

    Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; C

2023
Neoadjuvant chemotherapy with modified FOLFOXIRI for locally advanced rectal cancer to transform effectively EMVI and MRF from positive to negative: results of a long-term single center phase 2 clinical trial.
    BMC cancer, 2023, Jun-27, Volume: 23, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant

2023
Total neoadjuvant therapy with or without aflibercept in rectal cancer: 3-year results of GEMCAD-1402.
    Journal of the National Cancer Institute, 2023, Dec-06, Volume: 115, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fluorouracil; Human

2023
Optimal maintenance strategy following FOLFOX plus anti-EGFR induction therapy in patients with RAS wild type metastatic colorectal cancer: An individual patient data pooled analysis of randomised clinical trials.
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 190

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Colonic Neoplasms; Colorectal Neoplasms;

2023
Health-related quality of life in patients with RAS wild-type metastatic colorectal cancer treated with fluorouracil and folinic acid with or without panitumumab as maintenance therapy: a prespecified secondary analysis of the PanaMa (AIO KRK 0212) trial.
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 190

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Fluorouraci

2023
Sintilimab plus bevacizumab and CapeOx (BBCAPX) on first-line treatment in patients with RAS mutant, microsatellite stable, metastatic colorectal cancer: study protocol of a randomized, open-label, multicentric study.
    BMC cancer, 2023, Jul-18, Volume: 23, Issue:1

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; C

2023
Compliance and Toxicity of Total Neoadjuvant Therapy for Rectal Cancer: A Secondary Analysis of the OPRA Trial.
    International journal of radiation oncology, biology, physics, 2024, Jan-01, Volume: 118, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fluorouracil; Human

2024
Delta tocotrienol as a supplement to FOLFOXIRI in first-line treatment of metastatic colorectal cancer. A randomized, double-blind, placebo-controlled phase II study.
    Acta oncologica (Stockholm, Sweden), 2023, Volume: 62, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin;

2023
Single-arm, phase II study of intra-arterial chemotherapy plus total neoadjuvant therapy to optimise complete response in distal rectal cancer: a study protocol.
    BMJ open, 2023, 10-05, Volume: 13, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Phase II as Topi

2023
Preoperative sequential short-course radiation therapy and FOLFOX chemotherapy versus long-course chemoradiotherapy for locally advanced rectal cancer: a multicenter, randomized controlled trial (SOLAR trial).
    BMC cancer, 2023, Nov-03, Volume: 23, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant

2023
Sequential short-course radiation therapy and chemotherapy in the neoadjuvant treatment of rectal adenocarcinoma.
    Radiation oncology (London, England), 2019, Aug-19, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradi

2019
Early MRI predictors of disease-free survival in locally advanced rectal cancer from the GRECCAR 4 trial.
    The British journal of surgery, 2019, Volume: 106, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant

2019
Randomized controlled trial of 8 weeks' vs 12 weeks' interval between neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2020, Volume: 22, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fluorouracil; Human

2020
Association of Sex With Toxic Effects, Treatment Adherence, and Oncologic Outcomes in the CAO/ARO/AIO-94 and CAO/ARO/AIO-04 Phase 3 Randomized Clinical Trials of Rectal Cancer.
    JAMA oncology, 2020, 02-01, Volume: 6, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Female; Fluorouracil; Humans; Ma

2020
Resection or Stenting in the Treatment of Symptomatic Advanced Metastatic Rectal Cancer: A Dilemma.
    Anticancer research, 2019, Volume: 39, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camp

2019
Effect of interval between preoperative radiotherapy and surgery on clinical outcome and radiation proctitis in rectal cancer from FOWARC trial.
    Cancer medicine, 2020, Volume: 9, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Cohort Stu

2020
Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil, and Leucovorin Versus Oxaliplatin, 5-Fluorouracil, Leucovorin, and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Preoperative Chemoradiation: A Tri
    The oncologist, 2020, Volume: 25, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Chemotherapy, Adjuvant; Disease-Free Su

2020
Feasibility of modulated electro-hyperthermia in preoperative treatment for locally advanced rectal cancer: Early phase 2 clinical results.
    Neoplasma, 2020, Volume: 67, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Feasibility Studies

2020
Compliance and tolerability of short-course radiotherapy followed by preoperative chemotherapy and surgery for high-risk rectal cancer - Results of the international randomized RAPIDO-trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020, Volume: 147

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Fluoroura

2020
Compliance and tolerability of short-course radiotherapy followed by preoperative chemotherapy and surgery for high-risk rectal cancer - Results of the international randomized RAPIDO-trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020, Volume: 147

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Fluoroura

2020
Compliance and tolerability of short-course radiotherapy followed by preoperative chemotherapy and surgery for high-risk rectal cancer - Results of the international randomized RAPIDO-trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020, Volume: 147

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Fluoroura

2020
Compliance and tolerability of short-course radiotherapy followed by preoperative chemotherapy and surgery for high-risk rectal cancer - Results of the international randomized RAPIDO-trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020, Volume: 147

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Fluoroura

2020
Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label, multicenter, phase II randomized controlled trial.
    Trials, 2020, Apr-07, Volume: 21, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Clinical

2020
NORAD01-GRECCAR16 multicenter phase III non-inferiority randomized trial comparing preoperative modified FOLFIRINOX without irradiation to radiochemotherapy for resectable locally advanced rectal cancer (intergroup FRENCH-GRECCAR- PRODIGE trial).
    BMC cancer, 2020, May-29, Volume: 20, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Ad

2020
Neoadjuvant FOLFIRINOX followed by Chemoradiotherapy for Middle and Lower Rectal Cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2020, Jun-01, Volume: 21, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Deoxycytidine; Female; Flu

2020
Association of Treatment Adherence With Oncologic Outcomes for Patients With Rectal Cancer: A Post Hoc Analysis of the CAO/ARO/AIO-04 Phase 3 Randomized Clinical Trial.
    JAMA oncology, 2020, 09-01, Volume: 6, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Chi

2020
A prospective, single-arm, multicenter trial of neoadjuvant chemotherapy with mFOLFOX6 plus panitumumab without radiotherapy for locally advanced rectal cancer.
    International journal of colorectal disease, 2020, Volume: 35, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Neoadjuvant Therap

2020
Short-course radiation followed by mFOLFOX-6 plus avelumab for locally-advanced rectal adenocarcinoma.
    BMC cancer, 2020, Sep-01, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antin

2020
The long-term influence of hospital and surgeon volume on local control and survival in the randomized German Rectal Cancer Trial CAO/ARO/AIO-94.
    Surgical oncology, 2020, Volume: 35

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Germany; Hos

2020
Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma.
    Radiation oncology (London, England), 2020, Oct-07, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological

2020
Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma.
    Radiation oncology (London, England), 2020, Oct-07, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological

2020
Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma.
    Radiation oncology (London, England), 2020, Oct-07, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological

2020
Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma.
    Radiation oncology (London, England), 2020, Oct-07, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological

2020
Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma.
    Radiation oncology (London, England), 2020, Oct-07, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological

2020
Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma.
    Radiation oncology (London, England), 2020, Oct-07, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological

2020
Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma.
    Radiation oncology (London, England), 2020, Oct-07, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological

2020
Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma.
    Radiation oncology (London, England), 2020, Oct-07, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological

2020
Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma.
    Radiation oncology (London, England), 2020, Oct-07, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological

2020
Results of phase II trial of intensified neoadjuvant treatment with interdigitating radiotherapy and chemotherapy with oxaliplatin, 5-fluorouracil and folinic acid in patients with locally advanced rectal cancer (PROARCT trial).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2021, Volume: 155

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Middle Aged; Neoad

2021
Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric assessment: A planned interim analysis of a multicenter, phase II trial.
    Journal of geriatric oncology, 2021, Volume: 12, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Fluorouracil; Humans; Neoad

2021
Optimizing treatment sequencing of chemotherapy for patients with rectal cancer: The KIR randomized phase II trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2021, Volume: 155

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease-Free Survival; Fluor

2021
Quality of life in rectal cancer patients with or without oxaliplatin in the randomised CAO/ARO/AIO-04 phase 3 trial.
    European journal of cancer (Oxford, England : 1990), 2021, Volume: 144

    Topics: Adenocarcinoma, Mucinous; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ri

2021
Randomized phase II study comparing the efficacy and safety of SOX versus mFOLFOX6 as neoadjuvant chemotherapy without radiotherapy for locally advanced rectal cancer (KSCC1301).
    BMC cancer, 2021, Jan-05, Volume: 21, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2021
Tumor regression grading after preoperative hyperfractionated radiotherapy/chemoradiotherapy for locally advanced rectal cancers: interim analysis of phase III clinical study.
    Neoplasma, 2021, Volume: 68, Issue:3

    Topics: Chemoradiotherapy; Dose Fractionation, Radiation; Fluorouracil; Humans; Neoplasm Recurrence, Local;

2021
Deep regional hyperthermia with preoperative radiochemotherapy in locally advanced rectal cancer, a prospective phase II trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2021, Volume: 159

    Topics: Adenocarcinoma; Chemoradiotherapy; Fluorouracil; Humans; Hyperthermia; Neoadjuvant Therapy; Neoplasm

2021
Intensified Total Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer: A Phase II Trial.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2021, Volume: 33, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Neoadjuvant

2021
Use of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: Initial Results From the Pembrolizumab Arm of a Phase 2 Randomized Clinical Trial.
    JAMA oncology, 2021, Aug-01, Volume: 7, Issue:8

    Topics: Anal Canal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Chemo

2021
Cetuximab in treatment of metastatic colorectal cancer: final survival analyses and extended RAS data from the NORDIC-VII study.
    British journal of cancer, 2017, May-09, Volume: 116, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Colonic Neoplasms; Disease-F

2017
A Dose-finding and Biomarker Evaluation Phase Ib Study of Everolimus in Association With 5-Fluorouracil and Pelvic Radiotherapy as Neoadjuvant Treatment of Locally Advanced Rectal Cancer (E-LARC Study).
    Clinical colorectal cancer, 2017, Volume: 16, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cohort Studies; Combined Mo

2017
Pre-operative hyperfractionated concurrent radiochemotherapy for locally advanced rectal cancers: a phase II clinical study.
    The British journal of radiology, 2017, Volume: 90, Issue:1074

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Dose Fr

2017
Systemic Chemotherapy as Salvage Treatment for Locally Advanced Rectal Cancer Patients Who Fail to Respond to Standard Neoadjuvant Chemoradiotherapy.
    The oncologist, 2017, Volume: 22, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free

2017
Prospective randomized trial of neoadjuvant chemotherapy during the 'wait period' following preoperative chemoradiotherapy for rectal cancer: results of the WAIT trial.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2017, Volume: 19, Issue:11

    Topics: Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Female; Fluorourac

2017
Treatment of Locally Advanced Rectal Cancer: Turning Good Rationale Into Good Evidence?
    Diseases of the colon and rectum, 2017, Volume: 60, Issue:7

    Topics: Antineoplastic Agents; Camptothecin; Chemoradiotherapy; Colectomy; Dose-Response Relationship, Drug;

2017
A Multicenter Phase 2 Study on the Feasibility and Efficacy of Neoadjuvant Chemotherapy Without Radiotherapy for Locally Advanced Rectal Cancer.
    Annals of surgical oncology, 2017, Volume: 24, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Feasibili

2017
Preoperative long-course chemoradiotherapy plus adjuvant chemotherapy versus short-course radiotherapy without adjuvant chemotherapy both with delayed surgery for stage II-III resectable rectal cancer: 5-Year survival data of a randomized controlled trial
    Medicina (Kaunas, Lithuania), 2017, Volume: 53, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2017
A Phase 2 Study of 5-Fluorouracil (5-FU), Ziv-Aflibercept, and Radiation for the Preoperative and Adjuvant Treatment of Patients with Stage II/III Rectal Cancer.
    Cancer investigation, 2017, Sep-14, Volume: 35, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; C

2017
Postoperative Chemoradiotherapy After Local Resection for High-Risk T1 to T2 Low Rectal Cancer: Results of a Single-Arm, Multi-Institutional, Phase II Clinical Trial.
    Diseases of the colon and rectum, 2017, Volume: 60, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Colectomy

2017
Improved Metastasis- and Disease-Free Survival With Preoperative Sequential Short-Course Radiation Therapy and FOLFOX Chemotherapy for Rectal Cancer Compared With Neoadjuvant Long-Course Chemoradiotherapy: Results of a Matched Pair Analysis.
    International journal of radiation oncology, biology, physics, 2017, 10-01, Volume: 99, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2017
Selecting patients for hyperthermia combined with preoperative chemoradiotherapy for locally advanced rectal cancer.
    International journal of clinical oncology, 2018, Volume: 23, Issue:2

    Topics: Aged; Antigens, Neoplasm; Carbonic Anhydrase IX; Chemoradiotherapy; Combined Modality Therapy; Femal

2018
Tumor Regression Grading After Preoperative Chemoradiotherapy as a Prognostic Factor and Individual-Level Surrogate for Disease-Free Survival in Rectal Cancer.
    Journal of the National Cancer Institute, 2017, 12-01, Volume: 109, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradiotherapy, Adjuvant; Disease-Free

2017
Comparisons of Efficacy, Safety, and Cost of Chemotherapy Regimens FOLFOX4 and FOLFIRINOX in Rectal Cancer: A Randomized, Multicenter Study.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Apr-03, Volume: 24

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; China; Disease-Free Sur

2018
Preoperative radiotherapy and local excision of rectal cancer: Long-term results of a randomised study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 127, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Combined Mo

2018
Neoadjuvant rectal score as individual-level surrogate for disease-free survival in rectal cancer in the CAO/ARO/AIO-04 randomized phase III trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 07-01, Volume: 29, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemoradiotherapy, Adjuvant; Femal

2018
Hemoglobin level and XRCC1 polymorphisms to select patients with locally advanced rectal cancer candidate for neoadjuvant chemoradiotherapy with concurrent capecitabine and a platinum salt.
    Medical oncology (Northwood, London, England), 2018, May-02, Volume: 35, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuva

2018
Preoperative radiotherapy or chemoradiotherapy in rectal cancer - Is survival improved? An update of the "Nordic" LARC study in non-resectable cancers.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 127, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Fluorouracil; Human

2018
Impact of age on the efficacy of oxaliplatin in the preoperative chemoradiotherapy and adjuvant chemotherapy of rectal cancer: a post hoc analysis of the CAO/ARO/AIO-04 phase III trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 08-01, Volume: 29, Issue:8

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy,

2018
Repeating of local therapy of distant metastases increases overall survival in patients with synchronous metastasized rectal cancer-a monocentric analysis.
    International journal of colorectal disease, 2018, Volume: 33, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Fol

2018
A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS.
    British journal of cancer, 2018, Volume: 119, Issue:6

    Topics: Adult; Aged; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Administration Schedule; Feasib

2018
Consolidation mFOLFOX6 Chemotherapy After Chemoradiotherapy Improves Survival in Patients With Locally Advanced Rectal Cancer: Final Results of a Multicenter Phase II Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Dis

2018
FOLFIRINOX as induction treatment in rectal cancer patients with synchronous metastases: Results of the FFCD 1102 phase II trial.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 104

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2018
Challenges and solutions in the design and execution of the PROSPECT Phase II/III neoadjuvant rectal cancer trial (NCCTG N1048/Alliance).
    Clinical trials (London, England), 2019, Volume: 16, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2019
Total neoadjuvant approach with FOLFOXIRI plus bevacizumab followed by chemoradiotherapy plus bevacizumab in locally advanced rectal cancer: the TRUST trial.
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 110

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemoradioth

2019
Preoperative Volumetric Modulated Arc Therapy With Simultaneous Integrated Boost for Locally Advanced Distal Rectal Cancer.
    Technology in cancer research & treatment, 2019, 01-01, Volume: 18

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabin

2019
Preoperative FOLFOX in resectable locally advanced rectal cancer can be a safe and promising strategy: the R-NAC-01 study.
    Surgery today, 2019, Volume: 49, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2019
Leukocytosis and neutrophilia as independent prognostic immunological biomarkers for clinical outcome in the CAO/ARO/AIO-04 randomized phase 3 rectal cancer trial.
    International journal of cancer, 2019, 10-15, Volume: 145, Issue:8

    Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2019
Dose escalation of preoperative short-course radiotherapy followed by neoadjuvant chemotherapy in locally advanced rectal cancer: protocol for an open-label, single-centre, phase I clinical trial.
    BMJ open, 2019, 03-23, Volume: 9, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Fluorouracil; Hum

2019
Phase II Trial of Neoadjuvant Chemotherapy, Chemoradiotherapy, and Laparoscopic Surgery with Selective Lateral Node Dissection for Poor-Risk Low Rectal Cancer.
    Annals of surgical oncology, 2019, Volume: 26, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradioth

2019
Long-course preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for clinical T4 and fixed clinical T3 rectal cancer: long-term results of the randomized Polish II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2019, 08-01, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Consolid

2019
Long-course preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for clinical T4 and fixed clinical T3 rectal cancer: long-term results of the randomized Polish II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2019, 08-01, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Consolid

2019
Long-course preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for clinical T4 and fixed clinical T3 rectal cancer: long-term results of the randomized Polish II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2019, 08-01, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Consolid

2019
Long-course preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for clinical T4 and fixed clinical T3 rectal cancer: long-term results of the randomized Polish II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2019, 08-01, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Consolid

2019
Cost-effectiveness analysis of long-course oxaliplatin and bolus of fluorouracil based preoperative chemoradiotherapy vs. 5x5Gy radiation plus FOLFOX4 for locally advanced resectable rectal cancer.
    Radiation oncology (London, England), 2019, Jun-24, Volume: 14, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Decision Support Techniques; Fluo

2019
Efficacy and Safety of Two Neoadjuvant Strategies With Bevacizumab in MRI-Defined Locally Advanced T3 Resectable Rectal Cancer: Final Results of a Randomized, Noncomparative Phase 2 INOVA Study.
    Clinical colorectal cancer, 2019, Volume: 18, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab

2019
Neoadjuvant Chemotherapy With mFOLFOXIRI Without Routine Use of Radiotherapy for Locally Advanced Rectal Cancer.
    Clinical colorectal cancer, 2019, Volume: 18, Issue:4

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherap

2019
Chronomodulated capecitabine and adjuvant radiation in intermediate-risk to high-risk rectal cancer: a phase II study.
    American journal of clinical oncology, 2014, Volume: 37, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

2014
Evaluation of short-course radiotherapy followed by neoadjuvant bevacizumab, capecitabine, and oxaliplatin and subsequent radical surgical treatment in primary stage IV rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2013
Neoadjuvant chemoradiation for distal rectal cancer: 5-year updated results of a randomized phase 2 study of neoadjuvant combined modality chemoradiation for distal rectal cancer.
    International journal of radiation oncology, biology, physics, 2013, Jul-01, Volume: 86, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Agents; Camptothecin; Chemoradiotherapy;

2013
Phase II trial of preoperative radiochemotherapy with concurrent bevacizumab, capecitabine and oxaliplatin in patients with locally advanced rectal cancer.
    Radiation oncology (London, England), 2013, Apr-15, Volume: 8

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2013
Neoadjuvant treatment for unresectable rectal cancer: an interim analysis of a multicentre randomized study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 107, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Fluorouracil

2013
Prospective phase II trial of neoadjuvant chemo-radiotherapy with Oxaliplatin and Capecitabine in locally advanced rectal cancer (XELOXART).
    Medical oncology (Northwood, London, England), 2013, Volume: 30, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuva

2013
Phase II study of concomitant chemoradiotherapy with local hyperthermia and metronidazole for locally advanced fixed rectal cancer.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2013, Volume: 15, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradi

2013
A phase II trial of neoadjuvant IMRT-based chemoradiotherapy followed by one cycle of capecitabine for stage II/III rectal adenocarcinoma.
    Radiation oncology (London, England), 2013, May-29, Volume: 8

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Com

2013
Primary tumor location and bevacizumab effectiveness in patients with metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antimeta

2013
Neoadjuvant oxaliplatin and capecitabine and bevacizumab without radiotherapy for poor-risk rectal cancer: N-SOG 03 Phase II trial.
    Japanese journal of clinical oncology, 2013, Volume: 43, Issue:10

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2013
[Impact of CCND1 A870G polymorphism on acute adverse events in postoperative rectal cancer patients treated with adjuvant concurrent chemoradiotherapy].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2013, Volume: 35, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuva

2013
Postchemoradiation laparoscopic resection and intraoperative electron-beam radiation boost in locally advanced rectal cancer: long-term outcomes.
    Journal of cancer research and clinical oncology, 2013, Volume: 139, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2013
Palliative radiotherapy and chemotherapy instead of surgery in symptomatic rectal cancer with synchronous unresectable metastases: a phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Disease-Free Survival; Female; Fluorourac

2013
Watch and wait approach following extended neoadjuvant chemoradiation for distal rectal cancer: are we getting closer to anal cancer management?
    Diseases of the colon and rectum, 2013, Volume: 56, Issue:10

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiot

2013
Negative-balance isolated pelvic perfusion in patients with incurable symptomatic rectal cancer: results and drug dose correlation to adverse events.
    Acta radiologica (Stockholm, Sweden : 1987), 2014, Volume: 55, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Ca

2014
HER2 in high-risk rectal cancer patients treated in EXPERT-C, a randomized phase II trial of neoadjuvant capecitabine and oxaliplatin (CAPOX) and chemoradiotherapy (CRT) with or without cetuximab.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2013
Preoperative chemoradiation therapy with capecitabine/oxaliplatin and cetuximab in rectal cancer: long-term results of a prospective phase 1/2 study.
    International journal of radiation oncology, biology, physics, 2013, Dec-01, Volume: 87, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2013
Analysis of bevacizumab-based preoperative radiochemotherapy in patients with locally advanced rectal cancer on surgery-associated spectrum of complications.
    Annals of surgical oncology, 2014, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2014
Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal cancer: a phase 1 trial.
    International journal of radiation oncology, biology, physics, 2014, Feb-01, Volume: 88, Issue:2

    Topics: Adenocarcinoma; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Co

2014
Phase I/II study of neoadjuvant bevacizumab, erlotinib and 5-fluorouracil with concurrent external beam radiation therapy in locally advanced rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:1

    Topics: Adenocarcinoma; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; B

2014
Two-week course of preoperative chemoradiotherapy followed by delayed surgery for rectal cancer: a phase II multi-institutional clinical trial (KROG 11-02).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 110, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine;

2014
Two-week course of preoperative chemoradiotherapy followed by delayed surgery for rectal cancer: a phase II multi-institutional clinical trial (KROG 11-02).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 110, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine;

2014
Two-week course of preoperative chemoradiotherapy followed by delayed surgery for rectal cancer: a phase II multi-institutional clinical trial (KROG 11-02).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 110, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine;

2014
Two-week course of preoperative chemoradiotherapy followed by delayed surgery for rectal cancer: a phase II multi-institutional clinical trial (KROG 11-02).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 110, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine;

2014
Results in the elderly with locally advanced rectal cancer from the ACCOR12/PRODIGE 2 phase III trial: tolerance and efficacy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 110, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecit

2014
Neoadjuvant chemotherapy without routine use of radiation therapy for patients with locally advanced rectal cancer: a pilot trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Neoadjuvant chemotherapy without routine use of radiation therapy for patients with locally advanced rectal cancer: a pilot trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Neoadjuvant chemotherapy without routine use of radiation therapy for patients with locally advanced rectal cancer: a pilot trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Neoadjuvant chemotherapy without routine use of radiation therapy for patients with locally advanced rectal cancer: a pilot trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Neoadjuvant chemotherapy without routine use of radiation therapy for patients with locally advanced rectal cancer: a pilot trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Neoadjuvant chemotherapy without routine use of radiation therapy for patients with locally advanced rectal cancer: a pilot trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Neoadjuvant chemotherapy without routine use of radiation therapy for patients with locally advanced rectal cancer: a pilot trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Neoadjuvant chemotherapy without routine use of radiation therapy for patients with locally advanced rectal cancer: a pilot trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Neoadjuvant chemotherapy without routine use of radiation therapy for patients with locally advanced rectal cancer: a pilot trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2014
RAS mutations and cetuximab in locally advanced rectal cancer: results of the EXPERT-C trial.
    European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:8

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cape

2014
Five fractions of radiation therapy followed by 4 cycles of FOLFOX chemotherapy as preoperative treatment for rectal cancer.
    International journal of radiation oncology, biology, physics, 2014, Mar-15, Volume: 88, Issue:4

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Dose Fractionation, Radiation; Drug Admi

2014
Concomitant boost IMRT-based neoadjuvant chemoradiotherapy for clinical stage II/III rectal adenocarcinoma: results of a phase II study.
    Radiation oncology (London, England), 2014, Mar-07, Volume: 9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradi

2014
Chronicle: results of a randomised phase III trial in locally advanced rectal cancer after neoadjuvant chemoradiation randomising postoperative adjuvant capecitabine plus oxaliplatin (XELOX) versus control.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined

2014
Chronicle: results of a randomised phase III trial in locally advanced rectal cancer after neoadjuvant chemoradiation randomising postoperative adjuvant capecitabine plus oxaliplatin (XELOX) versus control.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined

2014
Chronicle: results of a randomised phase III trial in locally advanced rectal cancer after neoadjuvant chemoradiation randomising postoperative adjuvant capecitabine plus oxaliplatin (XELOX) versus control.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined

2014
Chronicle: results of a randomised phase III trial in locally advanced rectal cancer after neoadjuvant chemoradiation randomising postoperative adjuvant capecitabine plus oxaliplatin (XELOX) versus control.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined

2014
Capecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jun-20, Volume: 32, Issue:18

    Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy,

2014
Neoadjuvant chemoradiation therapy using concurrent S-1 and irinotecan in rectal cancer: impact on long-term clinical outcomes and prognostic factors.
    International journal of radiation oncology, biology, physics, 2014, Jul-01, Volume: 89, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Analysis of Variance; Antineoplastic Combined Chemo

2014
Polymorphisms in folate-metabolizing enzymes and response to 5-fluorouracil among patients with stage II or III rectal cancer (INT-0144; SWOG 9304).
    Cancer, 2014, Nov-01, Volume: 120, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Disease-Free Survival; Female; Fluorouracil; Folic Acid; Genetic Ass

2014
Neoadjuvant chronomodulated capecitabine with radiotherapy in rectal cancer: a phase II brunch regimen study.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycyt

2014
Pathological response and safety of two neoadjuvant strategies with bevacizumab in MRI-defined locally advanced T3 resectable rectal cancer: a randomized, noncomparative phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:11

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2014
Neoadjuvant capecitabine, bevacizumab and radiotherapy for locally advanced rectal cancer: results of a single-institute Phase I study.
    Journal of radiation research, 2014, Volume: 55, Issue:6

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Bevacizumab; Capecitabine; Deoxycytidine; F

2014
Oxaliplatin, fluorouracil, and leucovorin versus fluorouracil and leucovorin as adjuvant chemotherapy for locally advanced rectal cancer after preoperative chemoradiotherapy (ADORE): an open-label, multicentre, phase 2, randomised controlled trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuva

2014
Oxaliplatin, fluorouracil, and leucovorin versus fluorouracil and leucovorin as adjuvant chemotherapy for locally advanced rectal cancer after preoperative chemoradiotherapy (ADORE): an open-label, multicentre, phase 2, randomised controlled trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuva

2014
Oxaliplatin, fluorouracil, and leucovorin versus fluorouracil and leucovorin as adjuvant chemotherapy for locally advanced rectal cancer after preoperative chemoradiotherapy (ADORE): an open-label, multicentre, phase 2, randomised controlled trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuva

2014
Oxaliplatin, fluorouracil, and leucovorin versus fluorouracil and leucovorin as adjuvant chemotherapy for locally advanced rectal cancer after preoperative chemoradiotherapy (ADORE): an open-label, multicentre, phase 2, randomised controlled trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuva

2014
Phase II trial evaluating the feasibility of interdigitating folfox with chemoradiotherapy in locally advanced and metastatic rectal cancer.
    British journal of cancer, 2014, Nov-11, Volume: 111, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2014
Nuclear maspin expression as a predictive marker for fluorouracil treatment response in colon cancer.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:4

    Topics: Adjuvants, Immunologic; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Cell Nucleus; Chem

2015
Prediction of pathologic staging with magnetic resonance imaging after preoperative chemoradiotherapy in rectal cancer: pooled analysis of KROG 10-01 and 11-02.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 113, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemor

2014
Effect of neoadjuvant chemoradiation on tumor-infiltrating/associated lymphocytes in locally advanced rectal cancers.
    Anticancer research, 2014, Volume: 34, Issue:11

    Topics: Antimetabolites, Antineoplastic; Case-Control Studies; Chemoradiotherapy; Female; Fluorouracil; Foll

2014
Preoperative treatment with capecitabine, cetuximab and radiotherapy for primary locally advanced rectal cancer--a phase II clinical trial.
    Anticancer research, 2014, Volume: 34, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Co

2014
Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid--short Radiotherapy--rectum 3rd trial).
    BMC cancer, 2014, Nov-24, Volume: 14

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Moda

2014
Neoadjuvant sandwich treatment with oxaliplatin and capecitabine administered prior to, concurrently with, and following radiation therapy in locally advanced rectal cancer: a prospective phase 2 trial.
    International journal of radiation oncology, biology, physics, 2014, Dec-01, Volume: 90, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemother

2014
Neoadjuvant sandwich treatment with oxaliplatin and capecitabine administered prior to, concurrently with, and following radiation therapy in locally advanced rectal cancer: a prospective phase 2 trial.
    International journal of radiation oncology, biology, physics, 2014, Dec-01, Volume: 90, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemother

2014
Neoadjuvant sandwich treatment with oxaliplatin and capecitabine administered prior to, concurrently with, and following radiation therapy in locally advanced rectal cancer: a prospective phase 2 trial.
    International journal of radiation oncology, biology, physics, 2014, Dec-01, Volume: 90, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemother

2014
Neoadjuvant sandwich treatment with oxaliplatin and capecitabine administered prior to, concurrently with, and following radiation therapy in locally advanced rectal cancer: a prospective phase 2 trial.
    International journal of radiation oncology, biology, physics, 2014, Dec-01, Volume: 90, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemother

2014
Efficacy endpoints of radiation therapy group protocol 0247: a randomized, phase 2 study of neoadjuvant radiation therapy plus concurrent capecitabine and irinotecan or capecitabine and oxaliplatin for patients with locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2015, Jan-01, Volume: 91, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Ca

2015
No benefit of adjuvant Fluorouracil Leucovorin chemotherapy after neoadjuvant chemoradiotherapy in locally advanced cancer of the rectum (LARC): Long term results of a randomized trial (I-CNR-RT).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 113, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Female; F

2014
Adjuvant chemotherapy for rectal cancer patients treated with preoperative (chemo)radiotherapy and total mesorectal excision: a Dutch Colorectal Cancer Group (DCCG) randomized phase III trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant

2015
Kinetically guided neoadjuvant chemoradiotherapy based on 5-Fluorouracil in patients with locally advanced rectal cancer.
    Clinical pharmacokinetics, 2015, Volume: 54, Issue:5

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemoradiothe

2015
Prospective phase II trial of nimotuzumab in combination with radiotherapy and concurrent capecitabine in locally advanced rectal cancer.
    International journal of colorectal disease, 2015, Volume: 30, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cape

2015
Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Apr-01, Volume: 21, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemoradiotherapy; Disease-Free Survival; Fem

2015
GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer.
    Cancer research and treatment, 2015, Volume: 47, Issue:4

    Topics: Aged; Biomarkers, Tumor; Chemoradiotherapy, Adjuvant; Endoplasmic Reticulum Chaperone BiP; Female; F

2015
Preoperative chemoradiotherapy with 5-fluorouracil and oxaliplatin for locally advanced rectal cancer: long-term results of a phase II trial.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Disease-Free Surviva

2015
Postoperative irinotecan in resected stage II-III rectal cancer: final analysis of the French R98 Intergroup trial†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemot

2015
Carcinoma microsatellite instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for stage II rectal cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:4

    Topics: Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Chemotherapy, Adjuvant; Female; Fluorourac

2015
Induction FOLFOX followed by preoperative hyperfractionated radiotherapy plus bolus 5-fluorouracil in locally advanced rectal carcinoma: single arm phase I-II study.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Dose Fractionation,

2015
Clinical complete response (cCR) after neoadjuvant chemoradiotherapy and conservative treatment in rectal cancer. Findings from the ACCORD 12/PRODIGE 2 randomized trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 115, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Dise

2015
Phase II Trial of Preoperative Radiation With Concurrent Capecitabine, Oxaliplatin, and Bevacizumab Followed by Surgery and Postoperative 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX), and Bevacizumab in Patients With Locally Advanced Rectal Cancer: 5-
    The oncologist, 2015, Volume: 20, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecit

2015
Sandwich-like neoadjuvant therapy with bevacizumab for locally advanced rectal cancer: a phase II trial.
    Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2015
Pilot study of modified FOLFOX6 adjuvant chemotherapy for high-risk rectal cancer treated with neoadjuvant chemoradiotherapy.
    Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuva

2015
Phase I dose escalation trial of nitroglycerin in addition to 5-fluorouracil and radiation therapy for neoadjuvant treatment of operable rectal cancer.
    Surgery, 2015, Volume: 158, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2015
[Immediate results of combined therapy for local recurrences of rectal cancer].
    Voprosy onkologii, 2015, Volume: 61, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch

2015
Prognostic significance of clinical and pathological stages on locally advanced rectal carcinoma after neoadjuvant chemoradiotherapy.
    Radiation oncology (London, England), 2015, Jun-04, Volume: 10

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch

2015
Chemotherapy Alone for Patients With Stage II/III Rectal Cancer Undergoing Radical Surgery.
    The oncologist, 2015, Volume: 20, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Female; Fluorour

2015
Surgery with versus without preoperative concurrent chemoradiotherapy for mid/low rectal cancer: an interim analysis of a prospective, randomized trial.
    Chinese journal of cancer, 2015, Jun-10, Volume: 34, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Com

2015
NRG Oncology Radiation Therapy Oncology Group 0822: A Phase 2 Study of Preoperative Chemoradiation Therapy Using Intensity Modulated Radiation Therapy in Combination With Capecitabine and Oxaliplatin for Patients With Locally Advanced Rectal Cancer.
    International journal of radiation oncology, biology, physics, 2015, Sep-01, Volume: 93, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuva

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cana

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2015
Carcinoembryonic antigen has prognostic value for tumor downstaging and recurrence in rectal cancer after preoperative chemoradiotherapy and curative surgery: A multi-institutional and case-matched control study of KROG 14-12.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 116, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoem

2015
Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: Results of the BRANCH trial.
    Oncotarget, 2015, Oct-06, Volume: 6, Issue:30

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; C

2015
A multicenter phase II study of preoperative chemoradiotherapy with S-1 plus oxaliplatin for locally advanced rectal cancer (SHOGUN trial).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 116, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2015
Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:11

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capeci

2015
Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:11

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capeci

2015
Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:11

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capeci

2015
Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:11

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capeci

2015
Risk-Adapted Adjuvant Chemotherapy After Concomitant Fluoropyrimidine-Radiotherapy Neoadjuvant Treatment for Patients With Resectable CT3-4 or N+ Rectal Cancer: Five-Year Disease-Free Survival Results of a Single-Center Series.
    Clinical colorectal cancer, 2016, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total
    BMC cancer, 2015, Oct-23, Volume: 15

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothera

2015
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total
    BMC cancer, 2015, Oct-23, Volume: 15

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothera

2015
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total
    BMC cancer, 2015, Oct-23, Volume: 15

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothera

2015
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total
    BMC cancer, 2015, Oct-23, Volume: 15

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothera

2015
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total
    BMC cancer, 2015, Oct-23, Volume: 15

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothera

2015
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total
    BMC cancer, 2015, Oct-23, Volume: 15

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothera

2015
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total
    BMC cancer, 2015, Oct-23, Volume: 15

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothera

2015
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total
    BMC cancer, 2015, Oct-23, Volume: 15

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothera

2015
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total
    BMC cancer, 2015, Oct-23, Volume: 15

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothera

2015
Watch and wait policy after preoperative radiotherapy for rectal cancer; management of residual lesions that appear clinically benign.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2016, Volume: 42, Issue:2

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiot

2016
A Randomized Phase 2 Study of Neoadjuvant Chemoradiaton Therapy With 5-Fluorouracil/Leucovorin or Irinotecan/S-1 in Patients With Locally Advanced Rectal Cancer.
    International journal of radiation oncology, biology, physics, 2015, Dec-01, Volume: 93, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradi

2015
CoCStom trial: study protocol for a randomised trial comparing completeness of adjuvant chemotherapy after early versus late diverting stoma closure in low anterior resection for rectal cancer.
    BMC cancer, 2015, Nov-21, Volume: 15

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Digestive Syst

2015
Clinical research of intraperitoneal implantation of sustained-release 5-fluorouracil in advanced colorectal cancer.
    World journal of surgical oncology, 2015, Nov-24, Volume: 13

    Topics: Antineoplastic Agents; Colectomy; Colonic Neoplasms; Delayed-Action Preparations; Disease-Free Survi

2015
A phase II study of preoperative mFOLFOX6 with short-course radiotherapy in patients with locally advanced rectal cancer and liver-only metastasis.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2016, Volume: 118, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2016
A Feasibility Study of Neoadjuvant XELOX Without Radiotherapy for Locally Advanced Lower Rectal Cancer.
    Anticancer research, 2016, Volume: 36, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcin

2016
Phase I study of pre-operative continuous 5-FU and sorafenib with external radiation therapy in locally advanced rectal adenocarcinoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2016, Volume: 118, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Dose

2016
Oxaliplatin-containing Preoperative Therapy in Locally Advanced Rectal Cancer: Local Response, Toxicity and Long-term Outcome.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2016, Volume: 28, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease Progression

2016
Consolidation chemotherapy during neoadjuvant chemoradiation (CRT) for distal rectal cancer leads to sustained decrease in tumor metabolism when compared to standard CRT regimen.
    Radiation oncology (London, England), 2016, Feb-24, Volume: 11

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Chemoradiotherapy; Consolidation Chemotherapy; Double-B

2016
Disease Control, Survival, and Toxicity Outcome After Intensified Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer: A Single-Institution Experience.
    Clinical colorectal cancer, 2016, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2016
Pathologic Complete Response in Rectal Cancer: Can We Detect It? Lessons Learned From a Proposed Randomized Trial of Watch-and-Wait Treatment of Rectal Cancer.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Female; Fluorouraci

2016
Impact of Organ-Preserving Strategies on Anorectal Function in Patients with Distal Rectal Cancer Following Neoadjuvant Chemoradiation.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:4

    Topics: Adenocarcinoma; Aged; Anal Canal; Antimetabolites, Antineoplastic; Chemoradiotherapy; Fecal Incontin

2016
Early results of multicenter phase II trial of perioperative oxaliplatin and capecitabine without radiotherapy for high-risk rectal cancer: CORONA I study.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2016, Volume: 42, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; D

2016
Quality of Life Outcomes From a Phase 2 Trial of Short-Course Radiation Therapy Followed by FOLFOX Chemotherapy as Preoperative Treatment for Rectal Cancer.
    International journal of radiation oncology, biology, physics, 2016, 08-01, Volume: 95, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; C

2016
Effect of Interval (7 or 11 weeks) Between Neoadjuvant Radiochemotherapy and Surgery on Complete Pathologic Response in Rectal Cancer: A Multicenter, Randomized, Controlled Trial (GRECCAR-6).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 11-01, Volume: 34, Issue:31

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free

2016
Effect of Interval (7 or 11 weeks) Between Neoadjuvant Radiochemotherapy and Surgery on Complete Pathologic Response in Rectal Cancer: A Multicenter, Randomized, Controlled Trial (GRECCAR-6).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 11-01, Volume: 34, Issue:31

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free

2016
Effect of Interval (7 or 11 weeks) Between Neoadjuvant Radiochemotherapy and Surgery on Complete Pathologic Response in Rectal Cancer: A Multicenter, Randomized, Controlled Trial (GRECCAR-6).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 11-01, Volume: 34, Issue:31

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free

2016
Effect of Interval (7 or 11 weeks) Between Neoadjuvant Radiochemotherapy and Surgery on Complete Pathologic Response in Rectal Cancer: A Multicenter, Randomized, Controlled Trial (GRECCAR-6).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 11-01, Volume: 34, Issue:31

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-20, Volume: 34, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2016
Does the addition of oxaliplatin to preoperative chemoradiation benefit cT4 or fixed cT3 rectal cancer treatment? A subgroup analysis from a prospective study.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2016, Volume: 42, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Digestive S

2016
Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Anastomosis, Surgical; Anastomotic Leak; Antineoplastic Agents; Chemora

2016
Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Anastomosis, Surgical; Anastomotic Leak; Antineoplastic Agents; Chemora

2016
Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Anastomosis, Surgical; Anastomotic Leak; Antineoplastic Agents; Chemora

2016
Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Anastomosis, Surgical; Anastomotic Leak; Antineoplastic Agents; Chemora

2016
Acute Adverse Events and Postoperative Complications in a Randomized Trial of Preoperative Short-course Radiotherapy Versus Long-course Chemoradiotherapy for T3 Adenocarcinoma of the Rectum: Trans-Tasman Radiation Oncology Group Trial (TROG 01.04).
    Annals of surgery, 2017, Volume: 265, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Cause of Death; Chemoradiotherapy; Colectomy; Disease-Free Survival; Do

2017
A Phase II/III randomized controlled trial comparing perioperative versus postoperative chemotherapy with mFOLFOX6 for lower rectal cancer with suspected lateral pelvic node metastasis: Japan Clinical Oncology Group Study JCOG1310 (PRECIOUS study).
    Japanese journal of clinical oncology, 2017, Volume: 47, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Drug Administrat

2017
[Neoadjuvant short-term radiotherapy followed by FOLFOX chemotherapy : No standard treatment for rectal cancer].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2016, Volume: 192, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Fluorouracil; Guide

2016
[Inclusion of oxaliplatin in the multimodal treatment of locally advanced rectal cancer].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2017, Volume: 193, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherap

2017
Polymorphisms of MTHFR C677T and A1298C associated with survival in patients with colorectal cancer treated with 5-fluorouracil-based chemotherapy.
    International journal of clinical oncology, 2017, Volume: 22, Issue:3

    Topics: Aged; Colonic Neoplasms; Colorectal Neoplasms; Female; Fluorouracil; Haplotypes; Humans; Male; Methy

2017
Preoperative capecitabine and accelerated intensity-modulated radiotherapy in locally advanced rectal cancer: a phase II trial.
    American journal of clinical oncology, 2008, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycy

2008
Glutathione S-transferase P1 Ile105Val polymorphism is associated with haematological toxicity in elderly rectal cancer patients receiving preoperative chemoradiotherapy.
    Drugs & aging, 2008, Volume: 25, Issue:6

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; Fluorouracil;

2008
Phase II study of weekly intravenous oxaliplatin combined with oral daily capecitabine and radiotherapy with biologic correlates in neoadjuvant treatment of rectal adenocarcinoma.
    International journal of radiation oncology, biology, physics, 2008, Nov-01, Volume: 72, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Ch

2008
A modern regimen of pre-operative concurrent chemo-radiation therapy in locally advanced rectal cancer.
    Journal of surgical oncology, 2008, Sep-01, Volume: 98, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Combined Modalit

2008
A randomised phase III trial of adjuvant radio-chemotherapy comparing Irinotecan, 5FU and Leucovorin to 5FU and Leucovorin in patients with rectal cancer: a Hellenic Cooperative Oncology Group Study.
    European journal of cancer (Oxford, England : 1990), 2008, Volume: 44, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemother

2008
[Clinical observation of XELOX (Capecitabine puls Oxaliplatin): an adjuvant chemotherapy regimen used in stage III colorectal cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2008, Volume: 30, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; C

2008
Randomized phase III study comparing preoperative radiotherapy with chemoradiotherapy in nonresectable rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Aug-01, Volume: 26, Issue:22

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2008
Randomized phase III study comparing preoperative radiotherapy with chemoradiotherapy in nonresectable rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Aug-01, Volume: 26, Issue:22

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2008
Randomized phase III study comparing preoperative radiotherapy with chemoradiotherapy in nonresectable rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Aug-01, Volume: 26, Issue:22

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2008
Randomized phase III study comparing preoperative radiotherapy with chemoradiotherapy in nonresectable rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Aug-01, Volume: 26, Issue:22

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2008
Randomised trial comparing biweekly oxaliplatin plus oral capecitabine versus oxaliplatin plus i.v. bolus fluorouracil/leucovorin in metastatic colorectal cancer patients: results of the Southern Italy Cooperative Oncology study 0401.
    Journal of cancer research and clinical oncology, 2009, Volume: 135, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

2009
Thymidylate synthase genotypes and tumour regression in stage II/III rectal cancer patients after neoadjuvant fluorouracil-based chemoradiation.
    Cancer letters, 2008, Dec-18, Volume: 272, Issue:2

    Topics: Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Fluorouracil; Genotype; Humans; Male; Mid

2008
Phase I study of preoperative radiation therapy with concurrent infusional 5-fluorouracil and oxaliplatin followed by surgery and postoperative 5-fluorouracil plus leucovorin for T3/T4 rectal adenocarcinoma: ECOG E1297.
    International journal of radiation oncology, biology, physics, 2008, Sep-01, Volume: 72, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2008
[Irinotecan plus fuorouracil/leucovorin (FOLFIRI) as a second line chemotherapy for refractory or metastatic colorectal cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2008, Volume: 30, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Diseas

2008
Distal bowel surgical margin shorter than 1 cm after preoperative radiation for rectal cancer: is it safe?
    Annals of surgical oncology, 2008, Volume: 15, Issue:11

    Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Human

2008
Phase I trial of neoadjuvant chemoradiotherapy (CRT) with capecitabine and weekly irinotecan followed by laparoscopic total mesorectal excision (LTME) in rectal cancer patients.
    Investigational new drugs, 2009, Volume: 27, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camp

2009
Neoadjuvant treatment with single-agent cetuximab followed by 5-FU, cetuximab, and pelvic radiotherapy: a phase II study in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2009, Feb-01, Volume: 73, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Huma

2009
Safety of laparoscopic total mesorectal excision for low rectal cancer with preoperative chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2009, Volume: 13, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cohort Studies; Dose Fractionation,

2009
Neoadjuvant capecitabine combined with standard radiotherapy in patients with locally advanced rectal cancer: mature results of a phase II trial.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2008, Volume: 184, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemo

2008
Preoperative concomitant radiotherapy with oral capecitabine in advanced rectal cancer within 6 cm from anal verge.
    International journal of colorectal disease, 2009, Volume: 24, Issue:4

    Topics: Administration, Oral; Adult; Anal Canal; Antimetabolites, Antineoplastic; Capecitabine; Combined Mod

2009
Cetuximab in combination with capecitabine, irinotecan, and radiotherapy for patients with locally advanced rectal cancer: results of a Phase II MARGIT trial.
    International journal of radiation oncology, biology, physics, 2009, Aug-01, Volume: 74, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2009
Neo-adjuvant treatment of rectal cancer with capecitabine and oxaliplatin in combination with radiotherapy: a phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; D

2009
Preoperative short-course radiotherapy versus combined radiochemotherapy in locally advanced rectal cancer: a multi-centre prospectively randomised study of the Berlin Cancer Society.
    BMC cancer, 2009, Feb-06, Volume: 9

    Topics: Adult; Female; Fluorouracil; Follow-Up Studies; Germany; Humans; Male; Middle Aged; Neoadjuvant Ther

2009
Capecitabine initially concomitant to radiotherapy then perioperatively administered in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2009, Oct-01, Volume: 75, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality The

2009
Temporal patterns of fatigue predict pathologic response in patients treated with preoperative chemoradiation therapy for rectal cancer.
    International journal of radiation oncology, biology, physics, 2009, Nov-01, Volume: 75, Issue:3

    Topics: Activities of Daily Living; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidin

2009
Final results of a randomised phase III study on adjuvant chemotherapy with 5 FU and levamisol in colon and rectum cancer stage II and III by the Norwegian Gastrointestinal Cancer Group.
    Acta oncologica (Stockholm, Sweden), 2009, Volume: 48, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Agents; Antirheumatic Agents; Chemotherapy,

2009
Molecular response to cetuximab and efficacy of preoperative cetuximab-based chemoradiation in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Jun-10, Volume: 27, Issue:17

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2009
Longitudinal assessment of quality of life in rectal cancer patients with or without stomas following primary resection.
    Diseases of the colon and rectum, 2009, Volume: 52, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2009
Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2010, Mar-01, Volume: 76, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Jun-20, Volume: 27, Issue:18

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2009
Effect of total mesorectal excision on the outcome of rectal cancer after standardized postoperative radiochemotherapy: do randomized studies translate into clinical routine?
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2009, Volume: 185, Issue:6

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Humans; Incidence;

2009
Surgical treatment for locally advanced lower third rectal cancer after neoadjuvent chemoradiation with capecitabine: prospective phase II trial.
    World journal of surgical oncology, 2009, Jun-09, Volume: 7

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine

2009
Preoperative downstaging chemoradiation with concurrent irinotecan and capecitabine in MRI-defined locally advanced rectal cancer: a phase I trial (NWCOG-2).
    British journal of cancer, 2009, Sep-15, Volume: 101, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Combined Mo

2009
[Efficacy of FORFIRI regimen on oxaliplatin-based chemotherapy-failed advanced colorectal cancer].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic N

2009
Double blind randomized phase II study with radiation+5-fluorouracil+/-celecoxib for resectable rectal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 93, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Combined Modality Therapy; D

2009
Association between histological type of tumour growth and patient survival in t2-t3 lymph node-negative rectal cancer treated with sphincter-preserving total mesorectal excision.
    Pathology oncology research : POR, 2010, Volume: 16, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

2010
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2009
A phase I study of capecitabine, irinotecan, celecoxib, and radiation as neoadjuvant therapy of patients with locally advanced rectal cancer.
    American journal of clinical oncology, 2010, Volume: 33, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitab

2010
A phase II trial of neoadjuvant capecitabine combined with hyperfractionated accelerated radiation therapy in locally advanced rectal cancer.
    American journal of clinical oncology, 2010, Volume: 33, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplasti

2010
Increasing the rates of complete response to neoadjuvant chemoradiotherapy for distal rectal cancer: results of a prospective study using additional chemotherapy during the resting period.
    Diseases of the colon and rectum, 2009, Volume: 52, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucov

2009
Increasing the rates of complete response to neoadjuvant chemoradiotherapy for distal rectal cancer: results of a prospective study using additional chemotherapy during the resting period.
    Diseases of the colon and rectum, 2009, Volume: 52, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucov

2009
Increasing the rates of complete response to neoadjuvant chemoradiotherapy for distal rectal cancer: results of a prospective study using additional chemotherapy during the resting period.
    Diseases of the colon and rectum, 2009, Volume: 52, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucov

2009
Increasing the rates of complete response to neoadjuvant chemoradiotherapy for distal rectal cancer: results of a prospective study using additional chemotherapy during the resting period.
    Diseases of the colon and rectum, 2009, Volume: 52, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucov

2009
A phase II study of cetuximab, capecitabine and radiotherapy in neoadjuvant treatment of patients with locally advanced resectable rectal cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2010, Volume: 36, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Capec

2010
Phase II, randomized study of concomitant chemoradiotherapy followed by surgery and adjuvant capecitabine plus oxaliplatin (CAPOX) compared with induction CAPOX followed by concomitant chemoradiotherapy and surgery in magnetic resonance imaging-defined, l
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-10, Volume: 28, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; D

2010
Phase II, randomized study of concomitant chemoradiotherapy followed by surgery and adjuvant capecitabine plus oxaliplatin (CAPOX) compared with induction CAPOX followed by concomitant chemoradiotherapy and surgery in magnetic resonance imaging-defined, l
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-10, Volume: 28, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; D

2010
Phase II, randomized study of concomitant chemoradiotherapy followed by surgery and adjuvant capecitabine plus oxaliplatin (CAPOX) compared with induction CAPOX followed by concomitant chemoradiotherapy and surgery in magnetic resonance imaging-defined, l
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-10, Volume: 28, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; D

2010
Phase II, randomized study of concomitant chemoradiotherapy followed by surgery and adjuvant capecitabine plus oxaliplatin (CAPOX) compared with induction CAPOX followed by concomitant chemoradiotherapy and surgery in magnetic resonance imaging-defined, l
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-10, Volume: 28, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; D

2010
Neoadjuvant capecitabine and oxaliplatin before chemoradiotherapy and total mesorectal excision in MRI-defined poor-risk rectal cancer: a phase 2 trial.
    The Lancet. Oncology, 2010, Volume: 11, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Administrati

2010
Neoadjuvant capecitabine and oxaliplatin before chemoradiotherapy and total mesorectal excision in MRI-defined poor-risk rectal cancer: a phase 2 trial.
    The Lancet. Oncology, 2010, Volume: 11, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Administrati

2010
Neoadjuvant capecitabine and oxaliplatin before chemoradiotherapy and total mesorectal excision in MRI-defined poor-risk rectal cancer: a phase 2 trial.
    The Lancet. Oncology, 2010, Volume: 11, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Administrati

2010
Neoadjuvant capecitabine and oxaliplatin before chemoradiotherapy and total mesorectal excision in MRI-defined poor-risk rectal cancer: a phase 2 trial.
    The Lancet. Oncology, 2010, Volume: 11, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Administrati

2010
Neo-adjuvant chemo-radiation of rectal cancer with volumetric modulated arc therapy: summary of technical and dosimetric features and early clinical experience.
    Radiation oncology (London, England), 2010, Feb-19, Volume: 5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Carcinoma; Deoxycytidine; Femal

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-01, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2010
Preoperative capecitabine and pelvic radiation in locally advanced rectal cancer--is it equivalent to 5-FU infusion plus leucovorin and radiotherapy?
    International journal of radiation oncology, biology, physics, 2010, Volume: 76, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adju

2010
[Extended preoperative course of radiotherapy as component of combined and complex treatment of locally-advanced ampular rectal cancer].
    Voprosy onkologii, 2010, Volume: 56, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluoro

2010
A phase I study of bortezomib in combination with standard 5-fluorouracil and external-beam radiation therapy for the treatment of locally advanced or metastatic rectal cancer.
    Clinical colorectal cancer, 2010, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Boronic Acids;

2010
Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/leucovorin plus oxaliplatin (FOLFOX-6) as first-line treatment for metastatic colorectal cancer.
    International journal of cancer, 2011, Feb-01, Volume: 128, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Coloni

2011
Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer.
    The oncologist, 2010, Volume: 15, Issue:6

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemothera

2010
Pharmacogenetic analysis in neoadjuvant chemoradiation for rectal cancer: high incidence of somatic mutations and their relation with response.
    Pharmacogenomics, 2010, Volume: 11, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Capecitabine; Ch

2010
Technical feasibility of laparoscopic total mesorectal excision for patients with low rectal cancer after concurrent radiation and chemotherapy with bevacizumab plus FOLFOX.
    Surgical endoscopy, 2011, Volume: 25, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplast

2011
Medium-term results of neoadjuvant systemic chemotherapy using irinotecan, 5-fluorouracil, and leucovorin in patients with locally advanced rectal cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2010, Volume: 36, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Drug Adm

2010
Bevacizumab, capecitabine, amifostine, and preoperative hypofractionated accelerated radiotherapy (HypoArc) for rectal cancer: a Phase II study.
    International journal of radiation oncology, biology, physics, 2011, Jun-01, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amifostine; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibod

2011
Preoperative chemoradiation with irinotecan and capecitabine in patients with locally advanced resectable rectal cancer: long-term results of a Phase II study.
    International journal of radiation oncology, biology, physics, 2011, Mar-15, Volume: 79, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Combined Mo

2011
A safety and survival analysis of neoadjuvant bevacizumab with standard chemoradiation in a phase I/II study compared with standard chemoradiation in locally advanced rectal cancer.
    The oncologist, 2010, Volume: 15, Issue:8

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
High-dose-rate intraluminal brachytherapy during preoperative chemoradiation for locally advanced rectal cancers.
    World journal of gastroenterology, 2010, Sep-21, Volume: 16, Issue:35

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Brachytherapy; Capecitabine; Combined Modality T

2010
Adjuvant chemoradiotherapy of advanced resectable rectal cancer: results of a randomised trial comparing modulation of 5-fluorouracil with folinic acid or with interferon-α.
    British journal of cancer, 2010, Oct-12, Volume: 103, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Combined Chemotherapy Pro

2010
Preoperative chemoradiation with cetuximab, irinotecan, and capecitabine in patients with locally advanced resectable rectal cancer: a multicenter Phase II study.
    International journal of radiation oncology, biology, physics, 2011, Nov-01, Volume: 81, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplast

2011
Long-term results from a randomized phase II trial of neoadjuvant combined-modality therapy for locally advanced rectal cancer.
    Radiation oncology (London, England), 2010, Sep-29, Volume: 5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deoxycytidine;

2010
Long-term results from a randomized phase II trial of neoadjuvant combined-modality therapy for locally advanced rectal cancer.
    Radiation oncology (London, England), 2010, Sep-29, Volume: 5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deoxycytidine;

2010
Long-term results from a randomized phase II trial of neoadjuvant combined-modality therapy for locally advanced rectal cancer.
    Radiation oncology (London, England), 2010, Sep-29, Volume: 5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deoxycytidine;

2010
Long-term results from a randomized phase II trial of neoadjuvant combined-modality therapy for locally advanced rectal cancer.
    Radiation oncology (London, England), 2010, Sep-29, Volume: 5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deoxycytidine;

2010
Randomized trial of postoperative adjuvant therapy in Stage II and III rectal cancer to define the optimal sequence of chemotherapy and radiotherapy: 10-year follow-up.
    International journal of radiation oncology, biology, physics, 2011, Nov-15, Volume: 81, Issue:4

    Topics: Antineoplastic Agents; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Survival; Dose Fracti

2011
Late patient-reported toxicity after preoperative radiotherapy or chemoradiotherapy in nonresectable rectal cancer: results from a randomized Phase III study.
    International journal of radiation oncology, biology, physics, 2011, Nov-15, Volume: 81, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemoradiotherapy; Diagnostic

2011
Neoadjuvant bevacizumab, oxaliplatin, 5-fluorouracil, and radiation for rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplas

2012
KRAS and BRAF mutations and PTEN expression do not predict efficacy of cetuximab-based chemoradiotherapy in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2011, Nov-15, Volume: 81, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2011
Phase III trial of irinotecan plus infusional 5-fluorouracil/folinic acid versus irinotecan plus oxaliplatin as first-line treatment of advanced colorectal cancer.
    European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic N

2011
[Evaluation of bevacizumab combined with irinotecan-based regimen as the first-line treatment for patients with metastatic colorectal cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2010, Volume: 32, Issue:10

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclon

2010
Preoperative radiotherapy with capecitabine and mitomycin C in locally advanced rectal carcinoma.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antine

2011
Pathologic complete response after neoadjuvant treatment for rectal cancer decreases distant recurrence and could eradicate local recurrence.
    Annals of surgical oncology, 2011, Volume: 18, Issue:6

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combin

2011
Comparison of the micronucleus and chromosome aberration techniques for the documentation of cytogenetic damage in radiochemotherapy-treated patients with rectal cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Combined Modality Ther

2011
Preoperative chemoradiotherapy using concurrent capecitabine and irinotecan in magnetic resonance imaging-defined locally advanced rectal cancer: impact on long-term clinical outcomes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Mar-10, Volume: 29, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemother

2011
Preoperative oxaliplatin, capecitabine, and external beam radiotherapy in patients with newly diagnosed, primary operable, cT₃NxM0, low rectal cancer: a phase II study.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:2

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; C

2011
Preoperative oxaliplatin, capecitabine, and external beam radiotherapy in patients with newly diagnosed, primary operable, cT₃NxM0, low rectal cancer: a phase II study.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:2

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; C

2011
Preoperative oxaliplatin, capecitabine, and external beam radiotherapy in patients with newly diagnosed, primary operable, cT₃NxM0, low rectal cancer: a phase II study.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:2

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; C

2011
Preoperative oxaliplatin, capecitabine, and external beam radiotherapy in patients with newly diagnosed, primary operable, cT₃NxM0, low rectal cancer: a phase II study.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:2

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; C

2011
Randomized phase 3 trial comparing preoperative and postoperative chemoradiotherapy with capecitabine for locally advanced rectal cancer.
    Cancer, 2011, Aug-15, Volume: 117, Issue:16

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2011
Thymidylate synthase as a prognostic biomarker for locally advanced rectal cancer after multimodal treatment.
    Annals of surgical oncology, 2011, Volume: 18, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biom

2011
Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (StarPan/STAR-02 Study).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols;

2011
A pilot feasibility study of TNFerade™ biologic with capecitabine and radiation therapy followed by surgical resection for the treatment of rectal cancer.
    Oncology, 2010, Volume: 79, Issue:5-6

    Topics: Adult; Capecitabine; Combined Modality Therapy; Deoxycytidine; Feasibility Studies; Female; Fluorour

2010
Addition of bevacizumab to XELOX induction therapy plus concomitant capecitabine-based chemoradiotherapy in magnetic resonance imaging-defined poor-prognosis locally advanced rectal cancer: the AVACROSS study.
    The oncologist, 2011, Volume: 16, Issue:5

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agen

2011
Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized phase III trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jul-10, Volume: 29, Issue:20

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose Fractionation, Rad

2011
Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized phase III trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jul-10, Volume: 29, Issue:20

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose Fractionation, Rad

2011
Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized phase III trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jul-10, Volume: 29, Issue:20

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose Fractionation, Rad

2011
Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized phase III trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jul-10, Volume: 29, Issue:20

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose Fractionation, Rad

2011
Pre-operative bevacizumab, capecitabine, oxaliplatin and radiation among patients with locally advanced or low rectal cancer: a phase II trial.
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Co

2012
Oral glutamine supplementation during preoperative radiochemotherapy in patients with rectal cancer: a randomised double blinded, placebo controlled pilot study.
    Clinical nutrition (Edinburgh, Scotland), 2011, Volume: 30, Issue:5

    Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemical Phenomena; Chemoradiotherapy, Adjuvant

2011
Preoperative treatment with capecitabine, bevacizumab and radiotherapy for primary locally advanced rectal cancer--a two stage phase II clinical trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 102, Issue:1

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; B

2012
A phase II trial of neoadjuvant chemoradiation and local excision for T2N0 rectal cancer: preliminary results of the ACOSOG Z6041 trial.
    Annals of surgical oncology, 2012, Volume: 19, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape

2012
Radiation Therapy Oncology Group 0247: a randomized Phase II study of neoadjuvant capecitabine and irinotecan or capecitabine and oxaliplatin with concurrent radiotherapy for patients with locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, Mar-15, Volume: 82, Issue:4

    Topics: Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine;

2012
Radiation Therapy Oncology Group 0247: a randomized Phase II study of neoadjuvant capecitabine and irinotecan or capecitabine and oxaliplatin with concurrent radiotherapy for patients with locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, Mar-15, Volume: 82, Issue:4

    Topics: Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine;

2012
Radiation Therapy Oncology Group 0247: a randomized Phase II study of neoadjuvant capecitabine and irinotecan or capecitabine and oxaliplatin with concurrent radiotherapy for patients with locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, Mar-15, Volume: 82, Issue:4

    Topics: Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine;

2012
Radiation Therapy Oncology Group 0247: a randomized Phase II study of neoadjuvant capecitabine and irinotecan or capecitabine and oxaliplatin with concurrent radiotherapy for patients with locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, Mar-15, Volume: 82, Issue:4

    Topics: Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine;

2012
A phase II study of neoadjuvant chemoradiotherapy with oxaliplatin and capecitabine for rectal cancer.
    Cancer letters, 2011, Nov-28, Volume: 310, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemot

2011
T3+ and T4 rectal cancer patients seem to benefit from the addition of oxaliplatin to the neoadjuvant chemoradiation regimen.
    Annals of surgical oncology, 2012, Volume: 19, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape

2012
Preoperative radiotherapy combined with capecitabine chemotherapy in Chinese patients with locally advanced rectal cancer.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2011, Volume: 15, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuv

2011
Phase II trial of neoadjuvant chemotherapy with XELOX plus bevacizumab for locally advanced rectal cancer.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:8

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined C

2011
Phase II study of bevacizumab and chemoradiation in the preoperative or adjuvant treatment of patients with stage II/III rectal cancer.
    Clinical colorectal cancer, 2012, Volume: 11, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Co

2012
Identification of a biomarker profile associated with resistance to neoadjuvant chemoradiation therapy in rectal cancer.
    Annals of surgery, 2011, Volume: 254, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biom

2011
Neoadjuvant capecitabine, radiotherapy, and bevacizumab (CRAB) in locally advanced rectal cancer: results of an open-label phase II study.
    Radiation oncology (London, England), 2011, Aug-31, Volume: 6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Co

2011
[Effectiveness of neoadjuvant chemoradiotherapy of locally advanced rectal cancer in conjunction with local hyperthermia and metronidazole].
    Voprosy onkologii, 2011, Volume: 57, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; D

2011
Initial results of a randomized controlled trial comparing clinical and pathological downstaging of rectal cancer after preoperative short-course radiotherapy or long-term chemoradiotherapy, both with delayed surgery.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2012, Volume: 14, Issue:3

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Drug Administrat

2012
Preoperative concomitant boost intensity-modulated radiotherapy with oral capecitabine in locally advanced mid-low rectal cancer: a phase II trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 102, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality

2012
Preoperative concomitant boost intensity-modulated radiotherapy with oral capecitabine in locally advanced mid-low rectal cancer: a phase II trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 102, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality

2012
Preoperative concomitant boost intensity-modulated radiotherapy with oral capecitabine in locally advanced mid-low rectal cancer: a phase II trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 102, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality

2012
Preoperative concomitant boost intensity-modulated radiotherapy with oral capecitabine in locally advanced mid-low rectal cancer: a phase II trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 102, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality

2012
Acute toxicity of radiochemotherapy in rectal cancer patients: a risk particularly for carriers of the TGFB1 Pro25 variant.
    International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; C

2012
Phase II study of preoperative helical tomotherapy with a simultaneous integrated boost for rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Chemoradiotherapy; Disease-Free Survival; Dose Fract

2012
Short course chemotherapy followed by concomitant chemoradiotherapy and surgery in locally advanced rectal cancer: a randomized multicentric phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Comb

2012
Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer.
    British journal of cancer, 2011, Nov-22, Volume: 105, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studie

2011
Four-week neoadjuvant intensity-modulated radiation therapy with concurrent capecitabine and oxaliplatin in locally advanced rectal cancer patients: a validation phase II trial.
    International journal of radiation oncology, biology, physics, 2012, Jun-01, Volume: 83, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape

2012
[Pathological changes of rectal cancer after irinotecan, 5-fluorouracil or combined short-term radiotherapy].
    Zhonghua yi xue za zhi, 2011, Aug-09, Volume: 91, Issue:29

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Hum

2011
Genomic alterations in rectal tumors and response to neoadjuvant chemoradiotherapy: an exploratory study.
    Radiation oncology (London, England), 2011, Nov-18, Volume: 6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Chemoradiotherapy, Adjuvan

2011
Combination of irinotecan and 5-fluorouracil with radiation in locally advanced rectal adenocarcinoma.
    Journal of gastrointestinal cancer, 2012, Volume: 43, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradi

2012
A phase II study of neoadjuvant bevacizumab plus capecitabine and concomitant radiotherapy in patients with locally advanced rectal cancer.
    Angiogenesis, 2012, Volume: 15, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemo

2012
High-dose radiotherapy (60 Gy) with oral UFT/folinic acid and escalating doses of oxaliplatin in patients with non-resectable locally advanced rectal cancer (LARC): a phase I trial.
    Acta oncologica (Stockholm, Sweden), 2012, Volume: 51, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Feas

2012
Neoadjuvant treatment of mid-to-lower rectal cancer with oxaliplatin plus 5-fluorouracil and leucovorin in combination with radiotherapy: a Korean single center phase II study.
    International journal of clinical oncology, 2013, Volume: 18, Issue:2

    Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meie

2013
Phase II trial of concomitant neoadjuvant chemotherapy with oxaliplatin and capecitabine and intensity-modulated radiotherapy (IMRT) in rectal cancer.
    Journal of gastrointestinal cancer, 2012, Volume: 43, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cape

2012
Effect of neoadjuvant cetuximab, capecitabine, and radiotherapy for locally advanced rectal cancer: results of a phase II study.
    International journal of colorectal disease, 2012, Volume: 27, Issue:10

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabin

2012
Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, May-10, Volume: 30, Issue:14

    Topics: Adenocarcinoma; Adult; Aged; Analysis of Variance; Antibodies, Monoclonal; Antibodies, Monoclonal, H

2012
Characterisation of rectal motion during neo-adjuvant radiochemotherapy for rectal cancer with image-guided tomotherapy: implications for adaptive dose escalation strategies.
    Acta oncologica (Stockholm, Sweden), 2012, Volume: 51, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiot

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over S

2012
Comparison of magnetic resonance imaging and histopathological response to chemoradiotherapy in locally advanced rectal cancer.
    Annals of surgical oncology, 2012, Volume: 19, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Confidence In

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Mo

2012
Long-term follow-up of preoperative pelvic radiation therapy and concomitant boost irradiation in locally advanced rectal cancer patients: a multi-institutional phase II study (KROG 04-01).
    International journal of radiation oncology, biology, physics, 2012, Nov-15, Volume: 84, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Sur

2012
Dose-effect relationship in chemoradiotherapy for locally advanced rectal cancer: a randomized trial comparing two radiation doses.
    International journal of radiation oncology, biology, physics, 2012, Nov-15, Volume: 84, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brachytherapy; Denmark; Dose-Response Relationship, Ra

2012
Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal cancer: Hoosier Oncology Group GI03-53.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemoradiot

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2012
KRAS mutation status and clinical outcome of preoperative chemoradiation with cetuximab in locally advanced rectal cancer: a pooled analysis of 2 phase II trials.
    International journal of radiation oncology, biology, physics, 2013, Jan-01, Volume: 85, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antin

2013
Phase II study of preoperative radiotherapy and concomitant weekly intravenous oxaliplatin combined with oral capecitabine for stages II-III rectal cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2012, Volume: 14, Issue:8

    Topics: Administration, Intravenous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabi

2012
Multicenter phase II clinical trial of preoperative capecitabine with concurrent radiotherapy in patients with locally advanced rectal cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2013, Volume: 15, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxy

2013
Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a randomised controlled trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protoco

2012
Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a randomised controlled trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protoco

2012
Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a randomised controlled trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protoco

2012
Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a randomised controlled trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protoco

2012
Capecitabine-associated hand-foot-skin reaction is an independent clinical predictor of improved survival in patients with colorectal cancer.
    British journal of cancer, 2012, Nov-06, Volume: 107, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease-Free Surv

2012
[Preoperative chemoradiotherapy and postoperative chemotherapy with 5-fluorouracil and oxaliplatin in rectal cancer: initial results of the CAO/ARO/AIO-04 study].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2012, Volume: 83, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined

2012
Long-term results of 2 adjuvant trials reveal differences in chemosensitivity and the pattern of metastases between colon cancer and rectal cancer.
    Clinical colorectal cancer, 2013, Volume: 12, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplas

2013
Clinical outcome of the ACCORD 12/0405 PRODIGE 2 randomized trial in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Dec-20, Volume: 30, Issue:36

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Deo

2012
Neoadjuvant chemoradiotherapy with or without panitumumab in patients with wild-type KRAS, locally advanced rectal cancer (LARC): a randomized, multicenter, phase II trial SAKK 41/07.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chem

2013
A prospective pilot study of target-guided personalized chemotherapy with intensity-modulated radiotherapy in patients with early rectal cancer.
    American journal of clinical oncology, 2014, Volume: 37, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Combined-modality therapy for rectal cancer: analysis of potential differences in disease presentation, treatment adherence, and treatment outcome according to race.
    American journal of clinical oncology, 2014, Volume: 37, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Black or African American; Chemoradiotherapy,

2014
Does preoperative radiotherapy with postoperative chemotherapy increase acute side-effects and postoperative complications of total mesorectal excision? Report of the randomized Finnish rectal cancer trial.
    Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society, 2012, Volume: 101, Issue:4

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Co

2012
Preoperative short-course concurrent chemoradiation therapy followed by delayed surgery for locally advanced rectal cancer: a phase 2 multicenter study (KROG 10-01).
    International journal of radiation oncology, biology, physics, 2013, May-01, Volume: 86, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Dose Fractionation,

2013
Phase 2 study of preoperative radiation with concurrent capecitabine, oxaliplatin, and bevacizumab followed by surgery and postoperative 5-fluorouracil, leucovorin, oxaliplatin (FOLFOX), and bevacizumab in patients with locally advanced rectal cancer: ECO
    Cancer, 2013, Apr-15, Volume: 119, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2013
Phase II trial of first-line chemoradiotherapy with intensity-modulated radiation therapy followed by chemotherapy for synchronous unresectable distant metastases rectal adenocarcinoma.
    Radiation oncology (London, England), 2013, Jan-07, Volume: 8

    Topics: Adenocarcinoma; Adult; Aged; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidi

2013
Is the standardized uptake value of FDG-PET/CT predictive of pathological complete response in locally advanced rectal cancer treated with capecitabine-based neoadjuvant chemoradiation?
    Oncology, 2013, Volume: 84, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; De

2013
Clinical relevance of positron emission tomography/computed tomography-positive inguinal nodes in rectal cancer after neoadjuvant chemoradiation.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2013, Volume: 15, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Disease-F

2013
Long-term results of preoperative 5-fluorouracil-oxaliplatin chemoradiation therapy in locally advanced rectal cancer.
    Anticancer research, 2013, Volume: 33, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Dise

2013
Radiochemotherapy with short daily infusion of low-dose oxaliplatin, leucovorin, and 5-FU in T3-T4 unresectable rectal cancer: a phase II IATTGI study.
    International journal of radiation oncology, biology, physics, 2002, Oct-01, Volume: 54, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2002
Acute diarrhea during adjuvant therapy for rectal cancer: a detailed analysis from a randomized intergroup trial.
    International journal of radiation oncology, biology, physics, 2002, Oct-01, Volume: 54, Issue:2

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Fluorouracil; Humans; Infus

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2002
Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer.
    International journal of radiation oncology, biology, physics, 2003, Jan-01, Volume: 55, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined

2003
Early results from a phase I/II radiation dose-escalation study with concurrent amifostine and infusional 5-fluorouracil chemotherapy for preoperative treatment of unresectable or locally recurrent rectal carcinoma.
    Seminars in oncology, 2002, Volume: 29, Issue:6 Suppl 19

    Topics: Adenocarcinoma; Amifostine; Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytoprotecti

2002
Surgical adjuvant therapy of rectal carcinoma: a controlled evaluation of leucovorin, 5-fluorouracil and radiation therapy with or without interferon-alpha2b.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2003
A Phase II study of irinotecan in combination with 120-h infusion of 5-fluorouracil in patients with metastatic colorectal carcinoma: Japan Clinical Oncology Group Study (JCOG9703).
    Japanese journal of clinical oncology, 2003, Volume: 33, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug A

2003
Preoperative concurrent chemoradiotherapy in locally advanced rectal cancer with high-dose radiation and oxaliplatin-containing regimen: the Lyon R0-04 phase II trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-15, Volume: 21, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2003
Synchronous postoperative adjuvant chemoradiation therapy for locally advanced carcinoma of the rectum.
    International journal of colorectal disease, 2004, Volume: 19, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma; Chemotherapy, Adjuvant;

2004
Efficacy of chemoradiotherapy on pain relief in patients with intrapelvic recurrence of rectal cancer.
    Japanese journal of clinical oncology, 2003, Volume: 33, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Ther

2003
Randomised clinical trial of adjuvant postoperative RT vs. sequential postoperative RT plus 5-FU and levamisole in patients with stage II-III resectable rectal cancer: a final report.
    Journal of surgical oncology, 2003, Volume: 83, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease-Free Su

2003
Residual chromosomal damage after radiochemotherapy with and without amifostine detected by 24-color FISH.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2003, Volume: 179, Issue:7

    Topics: Aged; Amifostine; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Chromosome Aberrations; C

2003
Multicenter dose-finding study of concurrent capecitabine and radiotherapy as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2003, Aug-01, Volume: 56, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine

2003
Multicenter dose-finding study of concurrent capecitabine and radiotherapy as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2003, Aug-01, Volume: 56, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine

2003
Multicenter dose-finding study of concurrent capecitabine and radiotherapy as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2003, Aug-01, Volume: 56, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine

2003
Multicenter dose-finding study of concurrent capecitabine and radiotherapy as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2003, Aug-01, Volume: 56, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine

2003
Results of a randomized trial with or without 5-FU-based preoperative chemotherapy followed by postoperative chemotherapy in resected colon and rectal carcinoma.
    Japanese journal of clinical oncology, 2003, Volume: 33, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy;

2003
Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Aug-15, Volume: 21, Issue:16

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy

2003
Adjuvant vs. neoadjuvant radiochemotherapy for locally advanced rectal cancer: the German trial CAO/ARO/AIO-94.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2003, Volume: 5, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; Fluorouracil; Germany;

2003
Two different schedules of irinotecan (CPT-11) in patients with advanced colorectal carcinoma relapsing after a 5-fluorouracil and leucovorin combination. A randomized study.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:6

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasm

2003
Analysis of surgical salvage after failure of primary therapy in rectal cancer: results from Intergroup Study 0114.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Oct-01, Volume: 21, Issue:19

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2003
Randomized clinical trial of adjuvant radiotherapy and 5-fluorouracil infusion in colorectal cancer (AXIS).
    The British journal of surgery, 2003, Volume: 90, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antimetabolites, Antineoplastic; Colonic Neoplasms;

2003
[Preoperative chemoradiotherapy for locally advanced rectal cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colectomy;

2003
[Combined preoperative xeloda and radiotherapy for lower rectal cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2003, Volume: 25, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine

2003
Preoperative chemoradiotherapy versus preoperative radiotherapy in rectal cancer patients: assessment of acute toxicity and treatment compliance. Report of the 22921 randomised trial conducted by the EORTC Radiotherapy Group.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluo

2004
[Appropriate duration of postoperative oral adjuvant chemotherapy with HCFU for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:1

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; Diseas

2004
A Phase I trial of preoperative eniluracil plus 5-fluorouracil and radiation for locally advanced or unresectable adenocarcinoma of the rectum and colon.
    International journal of radiation oncology, biology, physics, 2004, Mar-01, Volume: 58, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplasti

2004
Phase I and pharmacokinetic study of the polyamine synthesis inhibitor SAM486A in combination with 5-fluorouracil/leucovorin in metastatic colorectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Amidines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Coloni

2004
Phase I study of 5-fluorouracil and leucovorin by continuous infusion chronotherapy and pelvic radiotherapy in patients with locally advanced or recurrent rectal cancer.
    International journal of radiation oncology, biology, physics, 2004, Apr-01, Volume: 58, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chronotherapy; Combined Modality Therapy; Diarrhea; Di

2004
Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu
    International journal of clinical oncology, 2004, Volume: 9, Issue:2

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2004
A pilot phase II study of capecitabine in advanced or recurrent colorectal cancer.
    Japanese journal of clinical oncology, 2004, Volume: 34, Issue:4

    Topics: Administration, Oral; Aged; Anorexia; Antimetabolites, Antineoplastic; Capecitabine; Colonic Neoplas

2004
[Influence of preoperative (hyperthermic) radiochemotherapy on manometric anal sphincter function in locally advanced rectal cancer].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2004, Volume: 180, Issue:5

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluor

2004
[An institution-randomized trial of 5-fluorouracil and l-leucovorin therapy given monthly versus every two months to patients with advanced colorectal carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Case-Control Studies; Colo

2004
Regional pelvic hyperthermia as an adjunct to chemotherapy (oxaliplatin, folinic acid, 5-fluorouracil) in pre-irradiated patients with locally recurrent rectal cancer: a pilot study.
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2004, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combine

2004
Sphincter preservation following preoperative radiotherapy for rectal cancer: report of a randomised trial comparing short-term radiotherapy vs. conventionally fractionated radiochemotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 72, Issue:1

    Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

2004
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer.
    British journal of cancer, 2004, Sep-13, Volume: 91, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2004
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer.
    British journal of cancer, 2004, Sep-13, Volume: 91, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2004
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer.
    British journal of cancer, 2004, Sep-13, Volume: 91, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2004
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer.
    British journal of cancer, 2004, Sep-13, Volume: 91, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2004
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer.
    British journal of cancer, 2004, Sep-13, Volume: 91, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2004
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer.
    British journal of cancer, 2004, Sep-13, Volume: 91, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2004
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer.
    British journal of cancer, 2004, Sep-13, Volume: 91, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2004
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer.
    British journal of cancer, 2004, Sep-13, Volume: 91, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2004
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer.
    British journal of cancer, 2004, Sep-13, Volume: 91, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2004
Chemoradiation with raltitrexed (Tomudex) in preoperative treatment of stage II-III resectable rectal cancer: a phase II study.
    International journal of radiation oncology, biology, physics, 2004, Sep-01, Volume: 60, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Female; Fluorouracil; Folic Acid; Follow-Up Studies; Hematini

2004
Chemoradiation with raltitrexed and oxaliplatin in preoperative treatment of stage II-III resectable rectal cancer: Phase I and II studies.
    International journal of radiation oncology, biology, physics, 2004, Sep-01, Volume: 60, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouraci

2004
A dose-finding and pharmacokinetic study of the matrix metalloproteinase inhibitor MMI270 (previously termed CGS27023A) with 5-FU and folinic acid.
    Cancer chemotherapy and pharmacology, 2005, Volume: 55, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms

2005
Leucovorin and fluorouracil vs levamisole and fluorouracil as adjuvant chemotherapy in rectal cancer.
    Oncology reports, 2004, Volume: 12, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorou

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Preoperative versus postoperative chemoradiotherapy for rectal cancer.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studi

2004
Phase I trial of capecitabine and weekly irinotecan in combination with radiotherapy for neoadjuvant therapy of rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Mar-01, Volume: 23, Issue:7

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Capec

2005
Oxaliplatin combined with infusional 5-fluorouracil and concomitant radiotherapy in inoperable and metastatic rectal cancer: a phase I trial.
    British journal of cancer, 2005, Feb-28, Volume: 92, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap

2005
Posttreatment TNM staging is a prognostic indicator of survival and recurrence in tethered or fixed rectal carcinoma after preoperative chemotherapy and radiotherapy.
    International journal of radiation oncology, biology, physics, 2005, Mar-01, Volume: 61, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Humans; Leucovo

2005
How accurate is magnetic resonance imaging in restaging rectal cancer in patients receiving preoperative combined chemoradiotherapy?
    Diseases of the colon and rectum, 2005, Volume: 48, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

2005
Intensified concurrent chemoradiotherapy with 5-fluorouracil and irinotecan as neoadjuvant treatment in patients with locally advanced rectal cancer.
    British journal of cancer, 2005, Apr-11, Volume: 92, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined

2005
Phase II study of irinotecan, 5-fluorouracil and leucovorin as first-line therapy for advanced colorectal cancer.
    Japanese journal of clinical oncology, 2005, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptoth

2005
A phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Drug Administration Sch

2005
Promising results of a cooperative group phase II trial of preoperative chemoradiation for locally advanced rectal cancer (TROG 9801).
    Diseases of the colon and rectum, 2005, Volume: 48, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Dose Fractionation, Radia

2005
Preoperative concurrent radiotherapy with capecitabine before total mesorectal excision in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2005, Oct-01, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Human

2005
Preoperative concurrent radiotherapy with capecitabine before total mesorectal excision in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2005, Oct-01, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Human

2005
Preoperative concurrent radiotherapy with capecitabine before total mesorectal excision in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2005, Oct-01, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Human

2005
Preoperative concurrent radiotherapy with capecitabine before total mesorectal excision in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2005, Oct-01, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Human

2005
Postoperative complications in patients irradiated pre-operatively for rectal cancer: report of a randomised trial comparing short-term radiotherapy vs chemoradiation.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2005, Volume: 7, Issue:4

    Topics: Antineoplastic Agents; Colectomy; Fluorouracil; Humans; Leucovorin; Neoadjuvant Therapy; Postoperati

2005
[Chronotherapy combining 5-fluorouracil, folinic acid and carboplatin as first line treatment in metastatic colorectal cancer. A phase 2 study].
    Pathologie-biologie, 2005, Volume: 53, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chronob

2005
Treatment of rectal cancer by chemoradiation followed by surgery: analysis and early clinical outcome in 66 patients.
    The Israel Medical Association journal : IMAJ, 2005, Volume: 7, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Endosonography; Fem

2005
Noninvasive magnetic resonance thermography of recurrent rectal carcinoma in a 1.5 Tesla hybrid system.
    Cancer research, 2005, Jul-01, Volume: 65, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidi

2005
Randomized controlled trial to evaluate laparoscopic surgery for colorectal cancer: Japan Clinical Oncology Group Study JCOG 0404.
    Japanese journal of clinical oncology, 2005, Volume: 35, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplas

2005
Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Combined Modal

2005
Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Combined Modal

2005
Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Combined Modal

2005
Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Combined Modal

2005
Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Combined Modal

2005
Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Combined Modal

2005
Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Combined Modal

2005
Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Combined Modal

2005
Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Combined Modal

2005
[Multicenter comparative study of the recurrence-inhibitory effect of oral fluoropyrimidine drugs in patients with colorectal cancer following curative resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:7

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Pr

2005
Multicenter phase II study of oral capecitabine plus irinotecan as first-line chemotherapy in advanced colorectal cancer: a Korean Cancer Study Group trial.
    Acta oncologica (Stockholm, Sweden), 2005, Volume: 44, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Ant

2005
[Clinical evaluation of chemotherapy with irinotecan (CPT-11), l-leucovorin (l-LV), 5-fluorouracil (5-FU), and UFT for metastatic or recurrent colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug A

2005
Phase II study of preoperative oxaliplatin, capecitabine and external beam radiotherapy in patients with rectal cancer: the RadiOxCape study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:12

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemot

2005
Preoperative radiation with concurrent chemotherapy for resectable rectal cancer: effect of dose escalation on pathologic complete response, local recurrence-free survival, disease-free survival, and overall survival.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil

2006
A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorou

2006
A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorou

2006
A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorou

2006
A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorou

2006
A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorou

2006
A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorou

2006
A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorou

2006
A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorou

2006
A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorou

2006
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Carcinoma; Carcinom

2005
A phase I/II study of oxaliplatin when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group (CCOG) study.
    British journal of cancer, 2005, Oct-31, Volume: 93, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Free

2005
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2005
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2005
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2005
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2005
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2005
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2005
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2005
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2005
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2005
Prediction of mesorectal nodal metastases after chemoradiation for rectal cancer: results of a randomised trial: implication for subsequent local excision.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2005, Volume: 76, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Combined Modality Therapy; Fluorouracil;

2005
Capecitabine in combination with preoperative radiation therapy in locally advanced, resectable, rectal cancer: a multicentric phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine;

2006
A phase I dose escalation study of continuous oral capecitabine in combination with oxaliplatin and pelvic radiation (XELOX-RT) in patients with locally advanced rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:1

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; C

2006
Combined radiotherapy, 5-fluorouracil continuous infusion and weekly oxaliplatin in advanced rectal cancer: a phase I study.
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:18

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Fluor

2005
Preoperative hyperfractionated chemoradiation for locally recurrent rectal cancer in patients previously irradiated to the pelvis: A multicentric phase II study.
    International journal of radiation oncology, biology, physics, 2006, Mar-15, Volume: 64, Issue:4

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents; Combined Modality Therapy; Dose Fractionat

2006
Adjuvant chemotherapy with folinic acid and 5-fluorouracil in patients with locally advanced rectal cancer previously treated by preoperative radiochemotherapy and curative tumor resection.
    International journal of colorectal disease, 2006, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Chemotherapy, Adjuvant; Colectomy; Drug Therapy, Combination; Female; Fluor

2006
Randomized phase II study of neoadjuvant combined-modality chemoradiation for distal rectal cancer: Radiation Therapy Oncology Group Trial 0012.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Feb-01, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemot

2006
Increased toxicity with gefitinib, capecitabine, and radiation therapy in pancreatic and rectal cancer: phase I trial results.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Feb-01, Volume: 24, Issue:4

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch

2006
Neoadjuvant capecitabine and oxaliplatin followed by synchronous chemoradiation and total mesorectal excision in magnetic resonance imaging-defined poor-risk rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Feb-01, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap

2006
Comparison of the efficacy of oral capecitabine versus bolus 5-FU in preoperative radiotherapy of locally advanced rectal cancer.
    Journal of Korean medical science, 2006, Volume: 21, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality

2006
Distal intramural spread of rectal cancer after preoperative radiotherapy: the results of a multicenter randomized clinical study.
    International journal of radiation oncology, biology, physics, 2006, May-01, Volume: 65, Issue:1

    Topics: Adult; Aged; Anal Canal; Antimetabolites, Antineoplastic; Chi-Square Distribution; Combined Modality

2006
Concurrent chemoradiation with capecitabine and weekly irinotecan as preoperative treatment for rectal cancer: results from a phase I/II study.
    British journal of cancer, 2006, Apr-10, Volume: 94, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Combined Modality

2006
Phase I/II study of preoperative oxaliplatin, fluorouracil, and external-beam radiation therapy in patients with locally advanced rectal cancer: Cancer and Leukemia Group B 89901.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jun-01, Volume: 24, Issue:16

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2006
Phase I/II study of oxaliplatin with weekly bolus fluorouracil and high-dose leucovorin (ROX) as first-line therapy for patients with colorectal cancer.
    Japanese journal of clinical oncology, 2006, Volume: 36, Issue:4

    Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dose-Respo

2006
Three-dimensional conformal radiotherapy combined with FOLFOX4 chemotherapy for unresectable recurrent rectal cancer.
    World journal of gastroenterology, 2006, Apr-28, Volume: 12, Issue:16

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluo

2006
A Phase I study of weekly intravenous oxaliplatin in combination with oral daily capecitabine and radiation therapy in the neoadjuvant treatment of rectal adenocarcinoma.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Capecitabine

2006
Influence of neoadjuvant radiochemotherapy combined with hyperthermia on the quality of life in rectum cancer patients.
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2006, Volume: 22, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluo

2006
A Phase II study of preoperative radiotherapy and concomitant weekly irinotecan in combination with protracted venous infusion 5-fluorouracil, for resectable locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Sep-01, Volume: 66, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy

2006
A phase II Study of the global dose and schedule of capecitabine in Japanese patients with metastatic colorectal cancer.
    Japanese journal of clinical oncology, 2006, Volume: 36, Issue:7

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Colonic Neoplasms;

2006
[Chemoembolization of bilateral internal iliac arteries in Miles operation].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2006, Volume: 31, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemoembolization, Therapeutic; Female; Fluor

2006
Complications, functional outcome and quality of life after intensive preoperative chemoradiotherapy for rectal cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2006, Volume: 32, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Phase III trial of fluorouracil-based chemotherapy regimens plus radiotherapy in postoperative adjuvant rectal cancer: GI INT 0144.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Aug-01, Volume: 24, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2006
The synchronization of chemotherapy to circadian rhythms and irradiation in pre-operative chemoradiation therapy with hyperthermia for local advanced rectal cancer.
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2006, Volume: 22, Issue:5

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Chronotherapy; Combined Modality Therapy; Fem

2006
Molecular responses of rectal cancer to preoperative chemoradiation.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2

    Topics: Adult; Aged; Biomarkers, Tumor; Celecoxib; Cyclooxygenase 2; Female; Fluorouracil; Humans; Immunohis

2006
[The prospective study on application of parenteral nutrition with alanyl-glutamine dipeptide in chemotherapy of gastrointestinal neoplasms patients].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Complement C3; Compl

2006
5-fluorouracil and weekly oxaliplatin combined with radiotherapy for locally advanced rectal cancer: surgical complications and long-term results.
    Archives of medical research, 2006, Volume: 37, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modalit

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Chemotherapy with preoperative radiotherapy in rectal cancer.
    The New England journal of medicine, 2006, Sep-14, Volume: 355, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2006
Phase I trial of cetuximab in combination with capecitabine, weekly irinotecan, and radiotherapy as neoadjuvant therapy for rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Dec-01, Volume: 66, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2006
Preoperative chemoradiotherapy with concomitant small field boost irradiation for locally advanced rectal cancer: a multi-institutional phase II study (KROG 04-01).
    Diseases of the colon and rectum, 2006, Volume: 49, Issue:11

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Dose Fractionation, Radiation; Female; Fluorouracil; H

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Phase II study of capecitabine (Xeloda) and concomitant boost radiotherapy in patients with locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2006, Nov-01, Volume: 66, Issue:3

    Topics: Adult; Aged; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Female;

2006
Phase II trial of preoperative chemoradiation with a hyperfractionated radiation boost in locally advanced rectal cancer.
    American journal of clinical oncology, 2006, Volume: 29, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality T

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
    Croatian medical journal, 2006, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2006
[Phase I study of postoperative concurrent chemoradiation with capecitabine as adjuvant treatment for stage II/III operable rectal cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deox

2006
A haplotype of the methylenetetrahydrofolate reductase gene predicts poor tumor response in rectal cancer patients receiving preoperative chemoradiation.
    Pharmacogenetics and genomics, 2006, Volume: 16, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

2006
Association between pathologic response in metastatic lymph nodes after preoperative chemoradiotherapy and risk of distant metastases in rectal cancer: An analysis of outcomes in a randomized trial.
    International journal of radiation oncology, biology, physics, 2007, Feb-01, Volume: 67, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Confidence Intervals; Disea

2007
Multicenter phase II trial of chemoradiation with oxaliplatin for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Jan-01, Volume: 25, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; C

2007
Multicenter phase II trial of chemoradiation with oxaliplatin for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Jan-01, Volume: 25, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; C

2007
Multicenter phase II trial of chemoradiation with oxaliplatin for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Jan-01, Volume: 25, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; C

2007
Multicenter phase II trial of chemoradiation with oxaliplatin for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Jan-01, Volume: 25, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; C

2007
Preoperative capecitabine with pelvic radiotherapy for locally advanced rectal cancer (phase I trial).
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006, Volume: 89, Issue:11

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; F

2006
Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2007
A phase I/II study of irinotecan when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group Study.
    British journal of cancer, 2007, Feb-26, Volume: 96, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cohort Studies; Combined

2007
A phase II study of capecitabine and irinotecan in combination with concurrent pelvic radiotherapy (CapIri-RT) as neoadjuvant treatment of locally advanced rectal cancer.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camp

2007
[Multicenter phase II study of modified FOLFIRI regimen in the advanced colorectal cancer patient refractory to fluoropyrimidine and oxaliplatin].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Co

2006
Phase I trial of preoperative hypofractionated intensity-modulated radiotherapy with incorporated boost and oral capecitabine in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2007, Apr-01, Volume: 67, Issue:5

    Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dose

2007
Preoperative radio-chemotherapy (RT-CT) in rectal cancer. Prospective study with postoperative RT-CT control group.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2007, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Amputation, Surgical; Antimetabolites, Antineoplastic; Colostomy; Combined Modality

2007
[Efficacy and toxicity of FOLFOX6 regimen in treating colorectal cancer patients with liver metastasis].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Disease-Free Surviva

2007
Bevacizumab, oxaliplatin, and capecitabine with radiation therapy in rectal cancer: Phase I trial results.
    International journal of radiation oncology, biology, physics, 2007, Jun-01, Volume: 68, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2007
Differences in toxicity across gender in patients treated with chemoradiation for rectal cancer.
    Australasian radiology, 2007, Volume: 51, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv

2007
Mitomycin-C/5-fluorouracil/leucovorin and hyperfractionated radiation therapy for rectal carcinoma: a phase II study with long-term follow-up.
    Clinical colorectal cancer, 2007, Volume: 6, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dise

2007
TIMP-1 is significantly associated with objective response and survival in metastatic colorectal cancer patients receiving combination of irinotecan, 5-fluorouracil, and folinic acid.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Jul-15, Volume: 13, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Carcinoembryonic An

2007
Preoperative chemoradiotherapy with capecitabine and oxaliplatin in locally advanced rectal cancer. A phase I-II multicenter study of the Dutch Colorectal Cancer Group.
    Annals of surgical oncology, 2007, Volume: 14, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycyti

2007
A phase II study of preoperative capecitabine and radiation therapy in patients with rectal cancer.
    American journal of clinical oncology, 2007, Volume: 30, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combi

2007
Preoperative chemoradiotherapy for rectal cancer: randomized trial comparing oral uracil and tegafur and oral leucovorin vs. intravenous 5-fluorouracil and leucovorin.
    International journal of radiation oncology, biology, physics, 2008, Jan-01, Volume: 70, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols

2008
Octreotide in the management of chemoradiotherapy-induced diarrhea refractory to loperamide in patients with rectal carcinoma.
    Oncology, 2006, Volume: 71, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma; Combined Modality Therapy; Diarrhea; Dose-Response Re

2006
Phase I-II trial of cetuximab, capecitabine, oxaliplatin, and radiotherapy as preoperative treatment in rectal cancer.
    International journal of radiation oncology, biology, physics, 2008, Mar-15, Volume: 70, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2008
Patients with curative resection of cT3-4 rectal cancer after preoperative radiotherapy or radiochemotherapy: does anybody benefit from adjuvant fluorouracil-based chemotherapy? A trial of the European Organisation for Research and Treatment of Cancer Rad
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-01, Volume: 25, Issue:28

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Fluorourac

2007
Patients with curative resection of cT3-4 rectal cancer after preoperative radiotherapy or radiochemotherapy: does anybody benefit from adjuvant fluorouracil-based chemotherapy? A trial of the European Organisation for Research and Treatment of Cancer Rad
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-01, Volume: 25, Issue:28

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Fluorourac

2007
Patients with curative resection of cT3-4 rectal cancer after preoperative radiotherapy or radiochemotherapy: does anybody benefit from adjuvant fluorouracil-based chemotherapy? A trial of the European Organisation for Research and Treatment of Cancer Rad
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-01, Volume: 25, Issue:28

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Fluorourac

2007
Patients with curative resection of cT3-4 rectal cancer after preoperative radiotherapy or radiochemotherapy: does anybody benefit from adjuvant fluorouracil-based chemotherapy? A trial of the European Organisation for Research and Treatment of Cancer Rad
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-01, Volume: 25, Issue:28

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Fluorourac

2007
Randomized, multicenter, phase IIb study of preoperative chemoradiotherapy in T3 mid-distal rectal cancer: raltitrexed + oxaliplatin + radiotherapy versus cisplatin + 5-fluorouracil + radiotherapy.
    International journal of radiation oncology, biology, physics, 2008, Feb-01, Volume: 70, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Mod

2008
Comparative outcome between chemoradiotherapy and lateral pelvic lymph node dissection following total mesorectal excision in rectal cancer.
    Annals of surgery, 2007, Volume: 246, Issue:5

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Digestive System Surgical Procedures; Disease

2007
Preoperative radiotherapy combined with 5 days per week capecitabine chemotherapy in locally advanced rectal cancer.
    British journal of cancer, 2007, Nov-19, Volume: 97, Issue:10

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Disease Pro

2007
Intensified irinotecan-based neoadjuvant chemoradiotherapy in rectal cancer: four consecutive designed studies to minimize acute toxicity and to optimize efficacy measured by pathologic complete response.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2007, Volume: 85, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Capec

2007
[Impact of perioperative chemotherapy on prognosis of colorectal cancer: a report of 82 cases].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2007
Phase I-II trial of concurrent capecitabine and oxaliplatin with preoperative intensity-modulated radiotherapy in patients with locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2008, Jul-01, Volume: 71, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Male;

2008
Integrating microarray and proteomics data to predict the response on cetuximab in patients with rectal cancer.
    Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2008

    Topics: Algorithms; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Artifi

2008
[Preoperative chemoradiotherapy with FOLFOX in low rectal cancer: a multicenter study].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2008, Volume: 11, Issue:2

    Topics: Adult; Aged; Chemotherapy, Adjuvant; Female; Fluorouracil; Formyltetrahydrofolates; Humans; Male; Mi

2008
Phase II study of capecitabine and oxaliplatin given prior to and concurrently with preoperative pelvic radiotherapy in patients with locally advanced rectal cancer.
    British journal of cancer, 2008, Apr-08, Volume: 98, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemother

2008
Irinotecan+5-fluorouracil with concomitant pre-operative radiotherapy in locally advanced non-resectable rectal cancer: a phase I/II study.
    British journal of cancer, 2008, Apr-08, Volume: 98, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy

2008
Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092).
    International journal of radiation oncology, biology, physics, 2008, Nov-01, Volume: 72, Issue:3

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Diarrhea; Dru

2008
Capecitabine, irinotecan, oxaliplatin (CAPIRINOX) and concomitant irradiation in advanced rectal cancer: the Lyon R-02-01 phase I trial.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2008, Volume: 20, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitab

2008
Preoperative treatment combining capecitabine with radiation therapy in rectal cancer: a GERCOR Phase II Study.
    Oncology, 2007, Volume: 73, Issue:3-4

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therap

2007
Phase I study of oxaliplatin in combination with capecitabine and radiotherapy as postoperative treatment for stage II and III rectal cancer.
    International journal of radiation oncology, biology, physics, 2008, Nov-01, Volume: 72, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Admin

2008
Adjuvant chemotherapy in cancer of the colon and rectum: demonstration of effectiveness of prolonged 5-FU chemotherapy in a prospectively controlled, randomized trial.
    The Surgical clinics of North America, 1981, Volume: 61, Issue:6

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Neo

1981
Adjuvant chemotherapy of large bowel cancer.
    Cancer treatment reviews, 1982, Volume: 9, Issue:3

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Floxu

1982
Chemotherapy after palliative resection of colorectal cancer. Yorkshire Gastrointestinal Tumour Group.
    The British journal of surgery, 1984, Volume: 71, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Th

1984
Activity of sequential low-dose methotrexate and fluorouracil in advanced colorectal carcinoma: attempt at correlation with tissue and blood levels of phosphoribosylpyrophosphate.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neopl

1984
Efficacy of MER immunotherapy when added to a regimen of 5-fluorouracil and methyl-CCNU following resection for carcinoma of the large bowel. A Veterans Administration Surgical Oncology Group report.
    Cancer, 1984, Jul-15, Volume: 54, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Clinical Trials as Topic;

1984
Metastatic colorectal carcinoma. A prospective randomized trial of Methyl-CCNU, 5-Fluorouracil (5-FU) and vincristine (MOF) versus MOF plus streptozotocin (MOF-Strep).
    Cancer, 1983, Jan-01, Volume: 51, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials

1983
Methyl-CCNU, 5-fluorouracil, vincristine, and streptozocin (MOF-STREP) in metastatic colo-rectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Clinical Trials as Topi

1983
Combined irradiation and three-drug chemotherapy in inoperable colorectal carcinoma.
    Acta radiologica. Oncology, 1982, Volume: 21, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Drug

1982
High-dose intermittent iv 5-FU and melphalan in advanced colorectal carcinoma.
    Cancer treatment reports, 1983, Volume: 67, Issue:6

    Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug The

1983
The systemic chemotherapy of hepatic metastases.
    Seminars in oncology, 1983, Volume: 10, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; D

1983
A trial of high-dose 5-fluorouracil with razoxane or adriamycin in the treatment of advanced adenocarcinoma of the gastrointestinal tract.
    American journal of clinical oncology, 1983, Volume: 6, Issue:4

    Topics: Adenocarcinoma; Clinical Trials as Topic; Colonic Neoplasms; Doxorubicin; Drug Administration Schedu

1983
Efficacy of prolonged intermittent therapy with combined 5-fluorouracil and methyl-CCNU following resection for carcinoma of the large bowel. A Veterans Administration Surgical Oncology Group report.
    Cancer, 1984, Jan-01, Volume: 53, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topi

1984
Adjuvant therapy for colo-rectal cancer.
    Annales chirurgiae et gynaecologiae, 1983, Volume: 72, Issue:6

    Topics: Adjuvants, Immunologic; BCG Vaccine; Clinical Trials as Topic; Colonic Neoplasms; Combined Modality

1983
An analysis of chemotherapy for colorectal carcinoma.
    Journal of surgical oncology, 1984, Volume: 25, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Combine

1984
Prospective randomized reappraisal of 5-fluorouracil in metastatic colorectal carcinoma. A comparative trial with 6-thioguanine.
    Cancer, 1984, Jun-15, Volume: 53, Issue:12

    Topics: Adenocarcinoma; Bone Marrow; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Female; Fluorour

1984
Prospective randomised trial of early cytotoxic therapy for recurrent colorectal carcinoma detected by serum CEA.
    Gut, 1984, Volume: 25, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Clinical Trials as Topic;

1984
Combination therapy with methotrexate and 5-fluorouracil: a prospective randomized clinical trial of order of administration.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:7

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical T

1984
Chemotherapy of advanced colorectal carcinoma: fluorouracil alone vs. two drug combinations using fluorouracil, hydroxyurea, semustine, dacarbazine, razoxane, and mitomycin. A phase III trial by the Eastern Cooperative Oncology Group (EST: 1278).
    American journal of clinical oncology, 1984, Volume: 7, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Ne

1984
[Effectiveness of combined and complex treatment of patients with operable cancer of the rectum].
    Voprosy onkologii, 1984, Volume: 30, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Clinical Trials as Topic; Cobalt Radioisotopes; Combined Modality Thera

1984
Complications following postoperative combined radiation and chemotherapy in adenocarcinoma of the rectum and rectosigmoid. A randomized trial that failed.
    Cancer, 1984, Dec-01, Volume: 54, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined M

1984
Combination chemotherapy with 5-fluorouracil, CCNU, and vincristine in metastatic colorectal carcinoma.
    American journal of clinical oncology, 1984, Volume: 7, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neopl

1984
A comparative study of oral tegafur and intravenous 5-fluorouracil in patients with metastatic colorectal cancer.
    American journal of clinical oncology, 1983, Volume: 6, Issue:2

    Topics: Administration, Oral; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Injections,

1983
Final results of a randomized trial on the treatment of rectal cancer with preoperative radiotherapy alone or in combination with 5-fluorouracil, followed by radical surgery. Trial of the European Organization on Research and Treatment of Cancer Gastroint
    Cancer, 1984, May-01, Volume: 53, Issue:9

    Topics: Adenocarcinoma; Clinical Trials as Topic; Colectomy; Combined Modality Therapy; Fluorouracil; Follow

1984
[Evaluation of preoperative administration of N1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) suppository in surgical adjuvant chemotherapy for large bowel cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:11

    Topics: Adult; Colonic Neoplasms; Colostomy; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative C

1984
Preliminary research on the evaluation of some prognostic factors in a randomized study of adjuvant immunochemotherapy in colorectal adenocarcinoma.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1984, Volume: 3, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Colonic Ne

1984
Randomized phase II studies in advanced colorectal carcinoma: a North Central Cancer Treatment Group study.
    Cancer treatment reports, 1983, Volume: 67, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Drug Evalu

1983
[Biological effect of recombined leukocyte alpha-2-interferon in metastasizing colorectal cancers].
    Deutsche medizinische Wochenschrift (1946), 1984, May-18, Volume: 109, Issue:20

    Topics: Adenocarcinoma; Adult; Colonic Neoplasms; Female; Fluorouracil; Herpes Labialis; Humans; Hypotension

1984
[Antiblastic therapy of nonadvanced colorectal cancer: preliminary results of a randomized therapeutic trial].
    Annali italiani di chirurgia, 1982, Volume: 54, Issue:1

    Topics: Adenocarcinoma; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluo

1982
[Clinical evaluation of combination chemotherapy of aclacinomycin A (ACM) and 5-fluorouracil (5-FU) for advanced carcinoma of gastrointestinal tract].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:4

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Bile Duct Neoplasms; Clinical Trials as Topic; Colonic Neo

1982
Methyl-CCNU and ftorafur in treatment of rectosigmoidal tumors and ftorafur capsules in treatment of colorectal tumors.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1981, Volume: 79

    Topics: Capsules; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Huma

1981
Adjuvant chemotherapy of colorectal carcinoma.
    Arizona medicine, 1982, Volume: 39, Issue:8

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Humans; Rectal Neo

1982
Combination chemotherapy containing semustine (MeCCNU) in patients with advanced colorectal cancer previously treated with 5-fluorouracil (5-Fu).
    American journal of clinical oncology, 1983, Volume: 6, Issue:2

    Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Fluorouracil;

1983
Systemic adjuvant therapy with BCG versus BCG + 5FU in colorectal cancer Dukes' Class C: updated critical analysis.
    Progress in experimental tumor research, 1980, Volume: 25

    Topics: Aged; BCG Vaccine; Carcinoembryonic Antigen; Clinical Trials as Topic; Colonic Neoplasms; Female; Fl

1980
Therapy of advanced colorectal carcinoma with 5-fluorouracil and cyclophosphamide in combination with either CCNU or methotrexate.
    Cancer, 1980, Feb-15, Volume: 45, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide

1980
Combination chemotherapy of advanced colorectal cancer with triazinate and ICRF-159 after failure of 5-Fluorouracil.
    Oncology, 1980, Volume: 37, Issue:5

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Drug Therapy, C

1980
MItomycin C, methyl-CCNU and 5-fluorouracil in the treatment of metastatic colorectal carcinoma.
    Cancer chemotherapy and pharmacology, 1980, Volume: 5, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; F

1980
The efficacy of 5-fluorouracil, mitomycin C, and methyl CCNU in advanced gastrointestinal malignancy.
    Oncology, 1981, Volume: 38, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Dru

1981
The effect of fluorouracil on survival in metastatic colorectal cancer fluorouracil response improves survival.
    The Australian and New Zealand journal of surgery, 1981, Volume: 51, Issue:1

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Humans; Neoplasm Metastasis; Prognosis; R

1981
Adjuvant chemotherapy and immunotherapy for colorectal cancer: preliminary communication.
    Journal of the Royal Society of Medicine, 1980, Volume: 73, Issue:3

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Immuno

1980
A controlled prospective trial of adjuvant razoxane in resectable colorectal cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1981, Volume: 79

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Humans; Piperazines; Razoxane; Rectal Neo

1981
[Background and experience of adjuvant cytostatic therapy in gastrointestinal cancer (author's transl)].
    Zentralblatt fur Chirurgie, 1981, Volume: 106, Issue:19

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluor

1981
Combination chemotherapy of advanced colorectal cancer utilizing 5-fluorouracil, semustine, dacarbazine, vincristine, and hydroxyurea: a phase III trial by the Eastern Cooperative Oncology Group (EST: 4275).
    Cancer, 1982, Apr-15, Volume: 49, Issue:8

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Administration

1982
Sequential chemotherapy of advanced colorectal cancer with standard or high-dose methotrexate followed by 5-fluorouracil.
    Medical and pediatric oncology, 1982, Volume: 10, Issue:2

    Topics: Aged; Clinical Trials as Topic; Colonic Neoplasms; Digestive System; Drug Therapy, Combination; Fluo

1982
Large bowel cancer: an overview.
    The Australian and New Zealand journal of surgery, 1982, Volume: 52, Issue:1

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Femal

1982
The role of pre-operative adjuvant therapy in the management of borderline operability rectal cancer.
    Clinical radiology, 1982, May-03, Volume: 33, Issue:3

    Topics: Clinical Trials as Topic; Fluorouracil; Humans; Preoperative Care; Prognosis; Rectal Neoplasms; Rect

1982
Combined adjuvant therapy of radically operated colorectal cancer patients. (chemotherapy, radiotherapy, and MER-BCG).
    Cancer chemotherapy and pharmacology, 1982, Volume: 8, Issue:1

    Topics: Adult; Aged; BCG Vaccine; Colonic Neoplasms; Female; Fluorouracil; Humans; Immunotherapy; Male; Midd

1982
High dose 5-fluorouracil (5-FU) and folinic acid in advanced colorectal cancer resistant to standard dose 5-FU treatment: results of a phase II study.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:10

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Resistance, Neoplasm; Drug The

1995
A pilot study of concomitant protracted venous infusion 5-fluorouracil and hyperfractionated radiotherapy in rectal tumors.
    American journal of clinical oncology, 1995, Volume: 18, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Human

1995
[Clinico-pathological studies on three preoperative combined treatments for rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:11

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorouracil; Humans; Hyper

1995
Five-year results of a randomized controlled trial of adjuvant chemotherapy for curatively resected colorectal carcinoma. The Colorectal Cancer Chemotherapy Study Group of Japan.
    Japanese journal of clinical oncology, 1995, Volume: 25, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Dis

1995
Cimetidine and survival with colorectal cancer.
    Lancet (London, England), 1995, Jul-08, Volume: 346, Issue:8967

    Topics: CD8-Positive T-Lymphocytes; Cimetidine; Colonic Neoplasms; Combined Modality Therapy; Disease-Free S

1995
[Is radiotherapy necessary in the control of colorectal cancer?].
    Ginecologia y obstetricia de Mexico, 1995, Volume: 63

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Cobalt Radioisotopes; Colectomy; Colonic

1995
Adjuvant post-operative radiotherapy vs radiotherapy plus 5-FU and levamisole in patients with TNM stage II-III resectable rectal cancer. A phase III randomized clinical trial. P.A.R. Cooperative Study Group.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1995, Volume: 21, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorou

1995
Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer.
    BMJ (Clinical research ed.), 1993, Mar-20, Volume: 306, Issue:6880

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neop

1993
Intraoperative radiotherapy for primary and recurrent rectal cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1995, Volume: 21, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

1995
[Definition, classification and combined treatment of locally invasive rectal neoplasms].
    Khirurgiia, 1994, Issue:10

    Topics: Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Humans; Neoplasm Invasiveness; Neoplasm

1994
Reversible hepatic steatosis in patients treated with interferon alfa-2a and 5-fluorouracil.
    Cancer, 1995, May-15, Volume: 75, Issue:10

    Topics: Adenocarcinoma; Colonic Neoplasms; Fatty Liver; Female; Fluorouracil; Humans; Interferon alpha-2; In

1995
Royal Marsden phase III trial of fluorouracil with or without interferon alfa-2b in advanced colorectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Disease-Free Survival; Drug Administration Schedu

1995
Relationship of acute gastrointestinal toxicity and the volume of irradiated small bowel in patients receiving combined modality therapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:6

    Topics: Adenocarcinoma; Combined Modality Therapy; Fluorouracil; Humans; Intestine, Small; Leucovorin; Neopl

1995
Continuous hepatic arterial infusion of 5-fluorouracil for unresectable colorectal liver metastases: phase II study.
    Surgery, 1995, Volume: 117, Issue:6

    Topics: Abdominal Pain; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Stu

1995
Different dose regimens of 5-fluorouracil and interferon-alpha in patients with metastatic colorectal carcinoma.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Sc

1995
Preoperative radiation and chemotherapy in the treatment of adenocarcinoma of the rectum.
    Annals of surgery, 1995, Volume: 221, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Case

1995
Double modulation of 5-fluorouracil in advanced colorectal cancer with low-dose interferon-alpha 2b and folinic acid. The "GISCAD" experience. Italian Group for the Study of Digestive Tract Cancer.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:11

    Topics: Adult; Aged; Colonic Neoplasms; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil;

1994
Efficacy of postoperative 5-FU, high-dose leucovorin, and sequential radiation therapy for clinically resectable rectal cancer.
    Cancer investigation, 1995, Volume: 13, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

1995
A pilot clinical trial of surgical adjuvant treatment with high-dose 6S-leucovorin/5-fluorouracil and radiation therapy for high-risk rectal carcinoma.
    Tumori, 1994, Oct-31, Volume: 80, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modali

1994
Long-term results of single course of adjuvant intraportal chemotherapy for colorectal cancer. Swiss Group for Clinical Cancer Research (SAKK)
    Lancet (London, England), 1995, Feb-11, Volume: 345, Issue:8946

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coloni

1995
[Preoperative radiochemotherapy in primary non-resectable rectal cancer].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1995, Volume: 171, Issue:2

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Chemotherapy, Adjuvant; Female; Fluorouracil;

1995
Weekly therapy with folinic acid and high-dose 5-fluorouracil 24-hour infusion in previously untreated patients with metastatic colorectal carcinoma.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil

1994
A phase I-II study of N-(phosphonacetyl)-L-aspartic acid (PALA) added to 5-fluorouracil and folinic acid in advanced colorectal cancer.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neop

1994
[Adjuvant therapy in colorectal carcinomas].
    Deutsche medizinische Wochenschrift (1946), 1994, Dec-02, Volume: 119, Issue:48

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Fluoroura

1994
The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease-Free Survival; Fluor

1994
5-Fluorouracil-interferon-alpha 2b adjuvant treatment of Dukes C colorectal cancer.
    Diseases of the colon and rectum, 1994, Volume: 37, Issue:7

    Topics: Aged; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Colonic Neoplasms; Confidence

1994
Adjuvant intraperitoneal 5-fluorouracil and intravenous leucovorin after colorectal cancer surgery: a randomized phase II placebo-controlled study.
    International journal of colorectal disease, 1994, Volume: 9, Issue:1

    Topics: Adult; Aged; Chemotherapy, Adjuvant; Colonic Neoplasms; Female; Fluorouracil; Humans; Infusions, Par

1994
Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery.
    The New England journal of medicine, 1994, Aug-25, Volume: 331, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Drug Therapy, Combination

1994
Downstaging of advanced rectal cancer following combined preoperative chemotherapy and high dose radiation.
    International journal of radiation oncology, biology, physics, 1994, Aug-30, Volume: 30, Issue:1

    Topics: Adult; Aged; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Fluorouracil;

1994
Local excision and postoperative radiation therapy for rectal cancer.
    American journal of clinical oncology, 1994, Volume: 17, Issue:5

    Topics: Actuarial Analysis; Adult; Aged; Aged, 80 and over; Anal Canal; Brachytherapy; Chemotherapy, Adjuvan

1994
Preoperative combined treatment with radiation, intraluminal hyperthermia, and 5-fluorouracil suppositories for patients with rectal cancer.
    Surgery today, 1993, Volume: 23, Issue:12

    Topics: Aged; Combined Modality Therapy; Female; Fluorouracil; Humans; Hyperthermia, Induced; Male; Middle A

1993
Randomized comparison of fluorouracil and leucovorin therapy versus fluorouracil, leucovorin, and cisplatin therapy in patients with advanced colorectal cancer.
    Cancer, 1994, Mar-15, Volume: 73, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Colonic Neoplasms

1994
5-fluorouracil and interferon-alpha-2a in advanced colorectal cancer. Results of two treatment schedules.
    Cancer, 1993, Dec-01, Volume: 72, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Catheters, Indwelling; Colonic Neoplasms; Drug Admin

1993
Preoperative 5-fluorouracil, low-dose leucovorin, and concurrent radiation therapy for rectal cancer.
    Cancer, 1994, Jan-15, Volume: 73, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Brachytherapy; Combined Modality Therapy; Drug Administration Schedule;

1994
A phase II study of continuous infusion 5-fluorouracil and leucovorin with weekly cisplatin in metastatic colorectal carcinoma.
    Cancer, 1993, Aug-01, Volume: 72, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Dose-Resp

1993
Pelvic radiotherapy with concurrent 5-fluorouracil modulated by leucovorin for rectal cancer: a phase II study.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1993, Volume: 5, Issue:3

    Topics: Adenocarcinoma; Aged; Combined Modality Therapy; Diarrhea; Female; Fluorouracil; Humans; Leucovorin;

1993
Large scale trial for adjuvant treatment in high risk resected colorectal cancers. Rationale to test the combination of loco-regional and systemic chemotherapy and to compare l-leucovorin + 5-FU to levamisole + 5-FU.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1993, Volume: 4 Suppl 2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal N

1993
Nonparametric estimation for the difference or ratio of median failure times.
    Biometrics, 1993, Volume: 49, Issue:2

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Mathematics; Models, Statistical; Rectal Neoplasms; Surviva

1993
Determination of the optimal dose of 5-fluorouracil when combined with low dose D,L-leucovorin and irradiation in rectal cancer: results of three consecutive phase II studies. EORTC Radiotherapy Group.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:10

    Topics: Combined Modality Therapy; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Met

1993
Phase II evaluation of recombinant alpha-2a-interferon and continuous infusion fluorouracil in previously untreated metastatic colorectal adenocarcinoma.
    Cancer, 1993, Feb-15, Volume: 71, Issue:4

    Topics: Abdominal Neoplasms; Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Administration Schedule; F

1993
[Phase I study of 5-fluorouracil and l-leucovorin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration

1993
Preoperative concurrent 5-fluorouracil infusion, mitomycin C and pelvic radiation therapy in tethered and fixed rectal carcinoma.
    International journal of radiation oncology, biology, physics, 1993, Apr-02, Volume: 25, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

1993
Pre-operative combined 5-FU, low dose leucovorin, and sequential radiation therapy for unresectable rectal cancer.
    International journal of radiation oncology, biology, physics, 1993, Apr-02, Volume: 25, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluo

1993
The efficacy of preoperative 5-fluorouracil, high-dose leucovorin, and sequential radiation therapy for unresectable rectal cancer.
    Cancer, 1993, Jun-01, Volume: 71, Issue:11

    Topics: Aged; Brachytherapy; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil;

1993
[Possible effect of administration methods on pharmacological action. Study of cytostatic therapy in advanced cancer].
    Lakartidningen, 1995, Dec-13, Volume: 92, Issue:50

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neop

1995
Prognostic evaluation of preoperative combined treatment for advanced cancer in the lower rectum with radiation, intraluminal hyperthermia, and 5-fluorouracil suppository.
    American journal of surgery, 1996, Volume: 171, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female;

1996
Prognostic factors of colorectal cancer. Results of multivariate analysis of curative resection cases with or without adjuvant chemotherapy.
    American journal of clinical oncology, 1996, Volume: 19, Issue:4

    Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemothe

1996
A quality-adjusted time without symptoms or toxicity (Q-TWiST) analysis of adjuvant radiation therapy and chemotherapy for resectable rectal cancer.
    Journal of the National Cancer Institute, 1996, Aug-07, Volume: 88, Issue:15

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cost of Illness; Fluorouraci

1996
A phase II trial of weekly infusional 5-fluorouracil in combination with low-dose leucovorin in patients with advanced colorectal cancer.
    Investigational new drugs, 1995, Volume: 13, Issue:3

    Topics: Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Administration Sche

1995
[Clinical evaluation of intra-arterial infusion chemotherapy for advanced or recurrent pelvic tumors with or without radiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplati

1996
Fluorouracil and leucovorin with or without interferon alfa-2b in advanced colorectal cancer: analysis of a prospective randomized phase III trial. Hellenic Cooperative Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:10

    Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Disease-F

1996
Intraoperative radiation therapy in integrated treatment of rectal cancers. Results of phase II study.
    Diseases of the colon and rectum, 1996, Volume: 39, Issue:12

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorouracil; Humans; Intraoperative Per

1996
Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Colon

1997
A phase II study of recombinant interferon-beta (r-hIFN-beta 1a) in combination with 5-fluorouracil (5-FU) in the treatment of patients with advanced colorectal carcinoma.
    British journal of cancer, 1997, Volume: 75, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Colonic Neop

1997
[Low-dose cisplatin added to continuous infusion of 5-fluorouracil or oral administration of UFT for inoperable advanced or recurrent colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Coloni

1997
[Reversible liver steatosis in patients treated with 5-fluorouracil and interferon-alpha].
    Ugeskrift for laeger, 1997, Feb-03, Volume: 159, Issue:6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Colonic Neoplasms; Fatty Liver; Female; Fluo

1997
Phase II study of trimetrexate, fluorouracil, and leucovorin for advanced colorectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colonic N

1997
Preoperative 5-FU, low-dose leucovorin, and radiation therapy for locally advanced and unresectable rectal cancer.
    International journal of radiation oncology, biology, physics, 1997, Jan-15, Volume: 37, Issue:2

    Topics: Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Sur

1997
A clinical trial to evaluate the worth of preoperative multimodality therapy in patients with operable carcinoma of the rectum: a progress report of National Surgical Breast and Bowel Project Protocol R-03.
    Diseases of the colon and rectum, 1997, Volume: 40, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluo

1997
Fluorouracil and high-dose leucovorin with radiotherapy as adjuvant therapy for rectal cancer. Results of a phase II study.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Diseas

1997
Improved surgical results after combining preoperative hyperthermia with chemotherapy and radiotherapy for patients with carcinoma of the rectum.
    Diseases of the colon and rectum, 1997, Volume: 40, Issue:4

    Topics: Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Hyperthermia, Ind

1997
Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated metastatic colorectal cancer.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neo

1997
Adjuvant postoperative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: initial results of intergroup 0114.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:5

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Adult; Aged; Agranulocytosis; Antidotes; Antimetabolites, An

1997
[A randomized comparative study of surgical adjuvant chemotherapy using 5-fluorouracil and dl-leucovorin with CDDP 5-FU and dl-leucovorin for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:7

    Topics: Adenocarcinoma; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Ci

1997
Selective chemoembolization in the management of hepatic metastases in refractory colorectal carcinoma: a phase II trial.
    Diseases of the colon and rectum, 1997, Volume: 40, Issue:7

    Topics: Abdominal Pain; Adult; Aged; Alkaline Phosphatase; Angiography; Antimetabolites, Antineoplastic; Ant

1997
Chemoradiation therapy and IORT in locally advanced rectal cancer: preliminary results in 36 patients.
    Frontiers of radiation therapy and oncology, 1997, Volume: 31

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluo

1997
[Preoperative intraluminal 5-FU osmosis chemotherapy as an adjuvant to radical resection for rectal cancer].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1996, Volume: 34, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy

1996
Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer. Norwegian Adjuvant Rectal Cancer Project Group.
    The British journal of surgery, 1997, Volume: 84, Issue:8

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Dis

1997
Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer. Norwegian Adjuvant Rectal Cancer Project Group.
    The British journal of surgery, 1997, Volume: 84, Issue:8

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Dis

1997
Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer. Norwegian Adjuvant Rectal Cancer Project Group.
    The British journal of surgery, 1997, Volume: 84, Issue:8

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Dis

1997
Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer. Norwegian Adjuvant Rectal Cancer Project Group.
    The British journal of surgery, 1997, Volume: 84, Issue:8

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Dis

1997
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for advanced colorectal carcinoma: a preliminary study.
    Journal of surgical oncology, 1997, Volume: 66, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Dis

1997
Increased apoptosis rate by hyperthermochemoradiotherapy for advanced rectal cancers.
    Surgery today, 1997, Volume: 27, Issue:8

    Topics: Administration, Rectal; Antimetabolites, Antineoplastic; Apoptosis; Chemotherapy, Adjuvant; Fluorour

1997
Association between blood transfusion and survival in a randomised multicentre trial of perioperative adjuvant portal chemotherapy in patients with colorectal cancer. The Swiss Group for Clinical Cancer Research (SAKK).
    The European journal of surgery = Acta chirurgica, 1997, Volume: 163, Issue:9

    Topics: Aged; Antimetabolites, Antineoplastic; Blood Transfusion; Chemotherapy, Adjuvant; Colonic Neoplasms;

1997
Is chemoradiation feasible in elderly patients? A study of 17 patients with anorectal carcinoma.
    Cancer, 1997, Oct-15, Volume: 80, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Mo

1997
Preoperative combined oral UFT plus leucovorin and radiation therapy for rectal cancer.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Combinati

1997
[Prospective controlled study on the usefulness of Carmofur as a postoperative adjuvant chemotherapy for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Admi

1997
Five-day continuous infusion of 5-fluorouracil and pulsed folinic acid in patients with metastatic colorectal carcinoma: an effective second-line regimen.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:11

    Topics: Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Administration Sche

1997
Postoperative adjuvant radiotherapy and 5-fluorouracil chemotherapy for rectal carcinoma.
    Australasian radiology, 1998, Volume: 42, Issue:1

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Hu

1998
Long-term weekly treatment of colorectal metastatic cancer with fluorouracil and leucovorin: results of a multicentric prospective trial of fluorouracil dosage optimization by pharmacokinetic monitoring in 152 patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Colon

1998
Acute treatment-related diarrhea during postoperative adjuvant therapy for high-risk rectal carcinoma.
    International journal of radiation oncology, biology, physics, 1998, Jun-01, Volume: 41, Issue:3

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Diarrhea; Fluorouracil; Huma

1998
Oxaliplatin combined to 5-fluorouracil and folinic acid: an effective therapy in patients with advanced colorectal cancer.
    Anti-cancer drugs, 1998, Volume: 9, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasm

1998
Bolus/infusional 5-fluorouracil and folinic acid. A report on two prospective, consecutive phase II studies with 5-fluorouracil dose escalation.
    British journal of cancer, 1998, Volume: 77, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antidotes; Antimetabolites, Antineoplastic; Carcinoma; Cohort Studie

1998
Adjuvant portal-vein infusion of fluorouracil and heparin in colorectal cancer: a randomised trial. European Organisation for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group, the Gruppo Interdisciplinare Valutazione Interv
    Lancet (London, England), 1998, Jun-06, Volume: 351, Issue:9117

    Topics: Aged; Anticoagulants; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic Neoplasms; Di

1998
Effects of pharmacokinetic modulating chemotherapy using oral UFT and continuous venous 5FU infusion on the prognosis of irradiated rectal carcinomas with p53 overexpression.
    International journal of oncology, 1998, Volume: 13, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy,

1998
Phase I dose escalating trial of hyperfractionated pre-operative chemoradiation for locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 1998, Aug-01, Volume: 42, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antidotes; Antineoplastic Combined Chemotherapy Prot

1998
A multistep therapy with subcutaneous low dose recombinant interleukin-2, 5-fluorouracil and leucovorin prolongs the response of metastatic colorectal cancer patients: a pilot study.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1998, Volume: 52, Issue:7-8

    Topics: Aged; Colonic Neoplasms; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Inte

1998
Schedule-selective biochemical modulation of 5-fluorouracil: a phase II study in advanced colorectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:9

    Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Disease-F

1995
[Phase II study on preoperative radio-chemo-thermotherapy in locally advanced rectal carcinoma].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1998, Volume: 174, Issue:11

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Follo

1998
[Chemoradiotherapy in treatment of cancer of the anal canal].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 1998, Volume: 2, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemotherapy,

1998
[Adjuvant radiochemotherapy with 5-FU and folinic acid in Dukes stage B and C rectum carcinoma: an interim analysis].
    Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, 1998, Volume: 115

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorou

1998
Hyperthermia for treatment of rectal cancer: evaluation for induction of multidrug resistance gene (mdr1) expression.
    International journal of cancer, 1999, Jan-05, Volume: 80, Issue:1

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Combined M

1999
5-fluorouracil and levofolinic acid with or without recombinant interferon-2b in patients with advanced colorectal carcinoma: a randomized multicenter study with stratification for tumor burden and liver involvement by the Southern Italy Oncology Group.
    Cancer, 1999, Feb-01, Volume: 85, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Analysis of Variance; Antidotes; Antineoplastic Combined Chemotherapy P

1999
Comparative evaluation of the complex treatment of rectal cancer patients (chemotherapy and X-ray therapy, Ukrain monotherapy).
    Drugs under experimental and clinical research, 1998, Volume: 24, Issue:5-6

    Topics: Adult; Aged; Alkaloids; Antineoplastic Agents; Berberine Alkaloids; Combined Modality Therapy; Femal

1998
Local excision of rectal carcinoma: a safe alternative for more advanced tumors?
    Journal of surgical oncology, 1999, Volume: 70, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

1999
Continuous delivery of venous 5-fluorouracil and arterial 5-fluorodeoxyuridine for hepatic metastases from colorectal cancer: feasibility and tolerance in a randomized phase II trial comparing flat versus chronomodulated infusion.
    Anti-cancer drugs, 1999, Volume: 10, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biological Clocks; Colonic Neoplasms; C

1999
[Systemic palliative chemotherapy with 5-fluorouracil and leucovorin in disseminated colorectal cancer].
    Ugeskrift for laeger, 1999, Jun-21, Volume: 161, Issue:25

    Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols;

1999
Phase I study of 5-fluorouracil administered by protracted venous infusion, leucovorin, and pelvic radiation therapy.
    Cancer, 1999, Aug-15, Volume: 86, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemotherapy, Adjuvant; Combined Modality

1999
Postoperative radiation and concomitant bolus fluorouracil with or without additional chemotherapy with fluorouracil and high-dose leucovorin in patients with high-risk rectal cancer: a randomized phase III study conducted by the Hellenic Cooperative Onco
    Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Adminis

1999
[Combination chemotherapy of continuous infusion 5-FU and daily low-dose CDDP in colorectal carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Administration Sc

1999
[Clinical evaluation of intermittent hepatic arterial infusion therapy with CDDP and 5-FU for liver metastasis of colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Admi

1999
[Weekly hepatic arterial infusion of high dose 5-fluorouracil for liver metastasis from colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:12

    Topics: Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorourac

1999
[Evaluation of intermittent hepatic arterial infusion chemotherapy for multiple liver metastasis of colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:12

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Administration Schedule; Femal

1999
Randomized, multicenter trial of fluorouracil plus leucovorin administered either via hepatic arterial or intravenous infusion versus fluorodeoxyuridine administered via hepatic arterial infusion in patients with nonresectable liver metastases from colore
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

2000
Preoperative radiochemotherapy in rectal cancer: long-term results of a phase II trial.
    International journal of radiation oncology, biology, physics, 2000, Jan-15, Volume: 46, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Follo

2000
Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02.
    Journal of the National Cancer Institute, 2000, Mar-01, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

2000
Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02.
    Journal of the National Cancer Institute, 2000, Mar-01, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

2000
Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02.
    Journal of the National Cancer Institute, 2000, Mar-01, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

2000
Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02.
    Journal of the National Cancer Institute, 2000, Mar-01, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

2000
Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02.
    Journal of the National Cancer Institute, 2000, Mar-01, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

2000
Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02.
    Journal of the National Cancer Institute, 2000, Mar-01, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

2000
Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02.
    Journal of the National Cancer Institute, 2000, Mar-01, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

2000
Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02.
    Journal of the National Cancer Institute, 2000, Mar-01, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

2000
Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02.
    Journal of the National Cancer Institute, 2000, Mar-01, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

2000
Comparison of fluorouracil with additional levamisole, higher-dose folinic acid, or both, as adjuvant chemotherapy for colorectal cancer: a randomised trial. QUASAR Collaborative Group.
    Lancet (London, England), 2000, May-06, Volume: 355, Issue:9215

    Topics: Adjuvants, Immunologic; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic Neoplasms;

2000
Oxaliplatin and raltitrexed combined with leucovorin-modulated 5-fluorouracil i.v. bolus every two weeks: a dose finding study in advanced previously treated colorectal carcinoma. Southern Italy Cooperative Oncology Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2000, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Dose-Resp

2000
Can p53 alterations be used to predict tumour response to pre-operative chemo-radiotherapy in locally advanced rectal cancer?
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2000, Volume: 56, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor;

2000
Preoperative radiochemotherapy in locally advanced or recurrent rectal cancer: regional radiofrequency hyperthermia correlates with clinical parameters.
    International journal of radiation oncology, biology, physics, 2000, Sep-01, Volume: 48, Issue:2

    Topics: Age Factors; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Follo

2000
Preoperative chemotherapy and pelvic radiation for tethered or fixed rectal cancer: a phase II dose escalation study.
    International journal of radiation oncology, biology, physics, 2000, Oct-01, Volume: 48, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2000
A prospective randomized trial comparing intravenous 5-fluorouracil and oral doxifluridine as postoperative adjuvant treatment for advanced rectal cancer.
    Annals of surgical oncology, 2000, Volume: 7, Issue:9

    Topics: Adenocarcinoma; Administration, Oral; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disea

2000
Intermittent use of amifostine during postoperative radiochemotherapy and acute toxicity in rectal cancer patients.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2000, Volume: 176, Issue:9

    Topics: Amifostine; Chemotherapy, Adjuvant; Combined Modality Therapy; Dose Fractionation, Radiation; Fluoro

2000
Preliminary analysis of a randomized clinical trial of adjuvant postoperative RT vs. postoperative RT plus 5-FU and levamisole in patients with TNM stage II-III resectable rectal cancer.
    Journal of surgical oncology, 2000, Volume: 75, Issue:2

    Topics: Adjuvants, Immunologic; Adult; Aged; Analysis of Variance; Antimetabolites, Antineoplastic; Antineop

2000
[Short-term hypofractionated radiotherapy followed by total mesorectal excision].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2000, Volume: 176, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv

2000
[First results of neoadjuvant simultaneious radiochemotherapy in advanced rectal carcinoma].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2000, Volume: 176, Issue:12

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Dose

2000
Preoperative combined modality therapy for clinically resectable uT3 rectal adenocarcinoma.
    International journal of radiation oncology, biology, physics, 2001, Mar-15, Volume: 49, Issue:4

    Topics: Adenocarcinoma; Anal Canal; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free

2001
Intravenous 5-fluorouracil versus oral doxifluridine as preoperative concurrent chemoradiation for locally advanced rectal cancer: prospective randomized trials.
    Japanese journal of clinical oncology, 2001, Volume: 31, Issue:1

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Floxuridin

2001
Randomized adjuvant study comparing two schemes of 5-fluorouracil and leucovorin in stage B2 and C colon adenocarcinoma: study design and preliminary safety results. Groupe d'Etude et de Recherche Clinique en Oncologie Radiotherapies.
    Seminars in oncology, 2001, Volume: 28, Issue:1 Suppl 1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Admini

2001
Improved overall survival among responders to preoperative chemoradiation for locally advanced rectal cancer.
    American journal of clinical oncology, 2001, Volume: 24, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female;

2001
A randomised phase II study of oxaliplatin alone versus oxaliplatin combined with 5-fluorouracil and folinic acid (Mayo Clinic regimen) in previously untreated metastatic colorectal cancer patients.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Disease-Free Surviva

2001
[Randomized trial of adjuvant chemotherapy with or without radiotherapy in rectal cancers].
    Annales de chirurgie, 2001, Volume: 126, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Fluorouracil; Humans; Leucov

2001
Adjuvant versus neoadjuvant radiochemotherapy for locally advanced rectal cancer. A progress report of a phase-III randomized trial (protocol CAO/ARO/AIO-94).
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2001, Volume: 177, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans;

2001
Combined chemo- and radiotherapy vs. radiotherapy alone in the treatment of primary, nonresectable adenocarcinoma of the rectum.
    International journal of radiation oncology, biology, physics, 2001, Jun-01, Volume: 50, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

2001
Early toxicity from preoperative radiotherapy with continuous infusion 5-fluorouracil for resectable adenocarcinoma of the rectum: a Phase II trial for the Trans-Tasman Radiation Oncology Group.
    International journal of radiation oncology, biology, physics, 2001, Jul-15, Volume: 50, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality T

2001
A phase I/II trial of three-dimensionally planned concurrent boost radiotherapy and protracted venous infusion of 5-FU chemotherapy for locally advanced rectal carcinoma.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Colectomy; Combined

2001
Phase II clinical trial of preoperative combined chemoradiation for T3 and T4 resectable rectal cancer: preliminary results.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Dose Fracti

2001
Ten years of preoperative chemoradiation for extraperitoneal T3 rectal cancer: acute toxicity, tumor response, and sphincter preservation in three consecutive studies.
    International journal of radiation oncology, biology, physics, 2001, Oct-01, Volume: 51, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Combined

2001
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autonomic Nervous System; Disease-Free Survival; Female

2001
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autonomic Nervous System; Disease-Free Survival; Female

2001
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autonomic Nervous System; Disease-Free Survival; Female

2001
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autonomic Nervous System; Disease-Free Survival; Female

2001
Adjuvant radio-chemotherapy in stage II-III rectal cancer with 24-hour infusion of high-dose 5-fluorouracil and folinic acid: evaluation of feasibility.
    Onkologie, 2001, Volume: 24, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2001
Randomized multicenter phase II study comparing a combination of fluorouracil and folinic acid and alternating irinotecan and oxaliplatin with oxaliplatin and irinotecan in fluorouracil-pretreated metastatic colorectal cancer patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Nov-15, Volume: 19, Issue:22

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; C

2001
Adjuvant 5FU plus levamisole in colonic or rectal cancer: improved survival in stage II and III.
    British journal of cancer, 2001, Nov-16, Volume: 85, Issue:10

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coloni

2001
[Clinical study on treatment of rectal carcinoma with Chinese herbal medicine and high dose fluorouracil emulsion via rectal infusion].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1999, Volume: 19, Issue:7

    Topics: Adenocarcinoma; Administration, Rectal; Adult; Antimetabolites, Antineoplastic; CD4-CD8 Ratio; Drug

1999
Radiotherapy, concomitant protracted-venous-infusion 5-fluorouracil, and surgery for ultrasound-staged T3 or T4 rectal cancer.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Endosonography; Fem

2001
Effect of preoperative radiochemotherapy on lymph node retrieval after resection of rectal cancer.
    Archives of surgery (Chicago, Ill. : 1960), 2002, Volume: 137, Issue:2

    Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Chi-Square Distributi

2002
Phase II study of a weekly 8-hour 5-fluorouracil and leucovorin infusion for patients with advanced colorectal cancer: dose adjusted according to its toxicity.
    Japanese journal of clinical oncology, 2001, Volume: 31, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dose-Response Relati

2001
Adjuvant therapy in rectal cancer: analysis of stage, sex, and local control--final report of intergroup 0114.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Apr-01, Volume: 20, Issue:7

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combin

2002
Randomized trial of postoperative adjuvant therapy in stage II and III rectal cancer to define the optimal sequence of chemotherapy and radiotherapy: a preliminary report.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Apr-01, Volume: 20, Issue:7

    Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol

2002
Influence of oxaliplatin on 5-fluorouracil plasma clearance and clinical consequences.
    Cancer chemotherapy and pharmacology, 2002, Volume: 49, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2002
Preoperative chemoradiation in patients with resectable rectal cancer: results on tumor response.
    Annals of surgical oncology, 2002, Volume: 9, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2002
Neoadjuvant therapy of rectal carcinoma with UFT-leucovorin plus radiotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Diseas

2002
Chemoradiation instead of surgery to treat mid and low rectal tumors: is it safe?
    Annals of surgical oncology, 2002, Volume: 9, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Flu

2002
Prolongation of postoperative disease-free interval and survival in human colorectal cancer by B.C.G. or B.C.G. plus 5-fluorouracil.
    Lancet (London, England), 1976, Apr-24, Volume: 1, Issue:7965

    Topics: Administration, Oral; BCG Vaccine; Colonic Neoplasms; Evaluation Studies as Topic; Fluorouracil; Fol

1976
Adjuvant chemotherapy in large-bowel cancer: demonstration of effectiveness of single agent chemotherapy in a prospectively controlled,, randomized trial.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Humans; Palliative Care; Prognosis; Rando

1978
Chemoimmunotherapy in disseminated melanoma and colorectal carcinoma.
    The Australian and New Zealand journal of surgery, 1978, Volume: 48, Issue:3

    Topics: Bacterial Vaccines; Colonic Neoplasms; Corynebacterium; Dacarbazine; Female; Fluorouracil; Humans; I

1978
[Initial experiences with a nation-wide Austrian study of adjuvant chemo- and immunotherapy of colorectal cancer following radical surgery].
    Acta medica Austriaca. Supplement, 1979, Volume: 6

    Topics: Antineoplastic Agents; Austria; Colectomy; Colonic Neoplasms; Drug Therapy, Combination; Fluorouraci

1979
A phase III study comparing the clinical utility of four regimens of 5-fluorouracil: a preliminary report.
    Cancer, 1977, Volume: 39, Issue:1

    Topics: Administration, Oral; Aged; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Drug Admi

1977
Gastrointestinal cancer--colon (surgery-radiotherapy). The role of radiation therapy in the management of rectosigmoid cancer.
    Cancer, 1977, Volume: 40, Issue:1 Suppl

    Topics: Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Neoplasm Me

1977
Management of gastrointestinal cancer.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluor

1977
Intraluminal fluorouracil chemotherapy adjunct to surgical procedures for respectable carcinoma of the colon and rectum.
    Surgery, gynecology & obstetrics, 1977, Volume: 145, Issue:4

    Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Female; Fluorouracil; Follow-Up Studies; H

1977
Adjuvant liver perfusion in colorectal cancer: initial results of a clinical trial.
    British medical journal, 1977, Nov-19, Volume: 2, Issue:6098

    Topics: Aged; Clinical Trials as Topic; Colonic Neoplasms; England; Female; Fluorouracil; Follow-Up Studies;

1977
Chemotherapy as an adjuvant to surgery for colorectal cancer. A follow-up report.
    Archives of surgery (Chicago, Ill. : 1960), 1978, Volume: 113, Issue:2

    Topics: Adenocarcinoma; Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Drug Eval

1978
Randomized trial of melphalan plus 5-fluorouracil (5-FU) versus methyl-CCNU plus 5-FU in patients with advanced colorectal cancer.
    Cancer treatment reports, 1978, Volume: 62, Issue:3

    Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; H

1978
Phase II trial of 5-fluorouracil plus melphalan in colorectal carcinoma.
    Cancer treatment reports, 1978, Volume: 62, Issue:3

    Topics: Adenocarcinoma; Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combinat

1978
Phase II trial of 5-fluorouracil, adriamycin, and mitomycin C in advanced colorectal cancer.
    Cancer treatment reports, 1978, Volume: 62, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Blood Cell Count; Clinical Trials as Topic; Colonic Neoplasms; Doxorubi

1978
Phase II trial of ftorafur with mitomycin C versus ftorafur with methyl-CCNU in untreated colorectal cancer.
    Cancer treatment reports, 1978, Volume: 62, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; Drug Ther

1978
Phase II trial of a combination of cyclosphamide, vincristine, and methotrexate in advanced colorectal carcinoma.
    Cancer treatment reports, 1978, Volume: 62, Issue:8

    Topics: Adult; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy,

1978
Chemotherapy for colorectal cancer with 5-fluorouracil, cyclophosphamide, and CCNU: comparison of oral and continuous iv administration of 5-fluorouracil.
    Cancer treatment reports, 1978, Volume: 62, Issue:10

    Topics: Administration, Oral; Adult; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Eva

1978
Sequential chemoimmunotherapy of colorectal cancer: evaluation of methotrexate, Baker's Antifol and levamisole.
    Cancer, 1978, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Colonic Neopl

1978
Chemotherapy of advanced measurable colon and rectal carcinoma with oral 5-fluorouracil, alone or in combination with cyclophosphamide or 6-thioguanine, with intravenous 5-fluorouracil or beta-2'-deoxythioguanosine or with oral 3(4-methyl-cyclohexyl)-1(2-
    Cancer, 1978, Volume: 42, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Colonic Neoplasms; Cyc

1978
A randomized study of two different schedules of methyl CCNU, 5-FU and vincristine for metastatic colorectal carcinoma.
    Cancer, 1979, Volume: 43, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Digestive System; D

1979
Phase I study of thymidine plus 5-fluorouracil infusions in advanced colorectal carcinoma.
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Flu

1979
Adjuvant therapy in colorectal cancer. (A randomized trial comparing radio-chemotherapy and radio-chemotherapy combined with the methanol extraction residue of BCG, MER).
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1979, Volume: 31, Issue:1

    Topics: BCG Vaccine; Clinical Trials as Topic; Colonic Neoplasms; Evaluation Studies as Topic; Female; Fluor

1979
Results of a prospective randomized study of hepatic artery infusion with 5-fluorouracil versus intravenous 5-fluorouracil in patients with hepatic metastases from colorectal cancer: A Central Oncology Group study.
    Surgery, 1979, Volume: 86, Issue:4

    Topics: Adenocarcinoma; Catheterization; Clinical Trials as Topic; Colonic Neoplasms; Female; Fluorouracil;

1979
Adjuvant chemotherapy for large bowel cancer: an optimistic appraisal.
    Minnesota medicine, 1979, Volume: 62, Issue:7

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Humans; Lymphatic Metastasis; Postoperati

1979
Adriamycin, mitomycin C, and 5-fluorouracil in combination for advanced colorectal adenocarcinoma previously treated with 5-fluorouracil.
    Cancer clinical trials, 1979,Winter, Volume: 2, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Doxorubicin; Dru

1979
Adjuvant cytotoxic liver perfusion for colorectal cancer.
    The British journal of surgery, 1979, Volume: 66, Issue:12

    Topics: Adenocarcinoma; Aged; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; England; Female;

1979
Cytotoxic perfusion for colorectal liver metastases.
    The British journal of surgery, 1978, Volume: 65, Issue:2

    Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Evaluation Studies as Topi

1978
Chemotherapy of large intestinal carcinoma. Current results and future prospects.
    Cancer, 1975, Volume: 36, Issue:6 Suppl

    Topics: Administration, Oral; Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Colonic Neoplasms

1975
Methyl-CCNU (NSC-95441) in advanced colorectal carcinoma after failure of 5-fluorouracil (NSC-19893) therapy.
    Cancer treatment reports, 1976, Volume: 60, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Blood Platelet Disorders; Clinical Trials as Topic; Colonic Neoplasms;

1976
Nitrosoureas: useful agents for the treatment of advanced gastrointestinal cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combin

1976
Current protocol approaches in large bowel cancer.
    Seminars in oncology, 1976, Volume: 3, Issue:4

    Topics: Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Th

1976
Randomized comparison of melphalan and 5-fluorouracil in the treatment of advanced gastrointestinal cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:9

    Topics: Adult; Aged; Biliary Tract Diseases; Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; F

1976
Adjuvant chemotherapy with 5-fluorouracil after surgical resection of colorectal carcinoma (COG protocol 7041). A preliminary report.
    American journal of surgery, 1977, Volume: 133, Issue:1

    Topics: Adenocarcinoma; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Prospective Studies; Rectal N

1977
Combination with 5-fluorouracil, methyl-CCNU and beta-2-deoxythioguanosine in advanced colo-rectal adenocarcinoma.
    Clinical oncology, 1977, Volume: 3, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Deoxyribonucleosides; Drug Therapy, Combination; Fem

1977
Methyl-CCNU versus methyl-CCNU and 5-fluorouracil in carcinoma of the large bowel.
    Cancer treatment reports, 1977, Volume: 61, Issue:8

    Topics: Arylsulfatases; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluo

1977
A double-blind comparison of intensive course 5-flourouracil by oral vs. intravenous route in the treatment of colorectal carcinoma.
    Cancer, 1975, Volume: 35, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Clinical Trials as Topic; Colonic Neoplasms; Evaluation Studie

1975
Therapy of advanced colorectal cancer with a combination of 5-fluorouracil, methyl-1,3-cis(2-chlorethyl)-1-nitrosourea, and vincristine.
    Journal of the National Cancer Institute, 1975, Volume: 54, Issue:1

    Topics: Antineoplastic Agents; Colonic Neoplasms; Cyclohexanes; Evaluation Studies as Topic; Female; Fluorou

1975
Chemotherapy as an adjuvant to surgery for colorectal cancer.
    Annals of surgery, 1975, Volume: 181, Issue:5

    Topics: Adenocarcinoma; Administration, Oral; Colonic Neoplasms; Fluorouracil; Humans; Postoperative Care; P

1975
Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma.
    Cancer, 1975, Volume: 36, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administratio

1975
Phase II study of epirubicin sequential methotrexate and 5-fluorouracil for advanced colorectal cancer.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Drug Admin

1992
[Multicenter cooperative study of pre- and post-operative adjuvant chemotherapy in the treatment of colorectal cancer. North Kyushu Co-operative Study Group for Cancer Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:12

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coloni

1992
Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum. Gastrointestinal Tumor Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; F

1992
Treatment of metastatic colorectal carcinoma with a combination of fluorouracil and recombinant interferon alfa-2b: preliminary data of a phase II study.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Fem

1992
Interferon alpha-2b, 5-fluorouracil, and folinic acid combination therapy in advanced colorectal cancer: preliminary results of a phase I/II trial.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Fem

1992
Treatment of refractory colorectal carcinomas with fluorouracil, folinic acid, and interferon alfa-2a.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil

1992
Fluorouracil plus interferon + folinic acid in regional and systemic therapy in colorectal cancer.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration

1992
Combined modality therapy of rectal cancer: decreased acute toxicity with the preoperative approach.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Adminis

1992
Phase I trial of postoperative 5-FU, radiation therapy, and high dose leucovorin for resectable rectal cancer.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:1

    Topics: Adenocarcinoma; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin;

1992
A pharmacokinetic comparison of intravenous versus intra-arterial folinic acid.
    British journal of cancer, 1992, Volume: 65, Issue:1

    Topics: Adenocarcinoma; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intra

1992
A phase I trial of recombinant human interleukin-1 beta alone and in combination with myelosuppressive doses of 5-fluorouracil in patients with gastrointestinal cancer.
    Blood, 1991, Sep-15, Volume: 78, Issue:6

    Topics: Adult; Aged; Blood Glucose; Bone Marrow; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combinati

1991
Relative importance of dose, body surface area, sex, and age for 5-fluorouracil clearance.
    Oncology, 1991, Volume: 48, Issue:4

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Surface Area; Breast

1991
Effective surgical adjuvant therapy for high-risk rectal carcinoma.
    The New England journal of medicine, 1991, Mar-14, Volume: 324, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

1991
Effective surgical adjuvant therapy for high-risk rectal carcinoma.
    The New England journal of medicine, 1991, Mar-14, Volume: 324, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

1991
Effective surgical adjuvant therapy for high-risk rectal carcinoma.
    The New England journal of medicine, 1991, Mar-14, Volume: 324, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

1991
Effective surgical adjuvant therapy for high-risk rectal carcinoma.
    The New England journal of medicine, 1991, Mar-14, Volume: 324, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

1991
NCI advocates use of adjuvant therapy for rectal cancer.
    American family physician, 1991, Volume: 43, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Nat

1991
Randomized study of continuous infusion fluorouracil versus fluorouracil plus cisplatin in patients with metastatic colorectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin

1990
Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Female; Fluorouracil; Humans; Inf

1990
Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Female; Fluorouracil; Humans; Inf

1990
Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Female; Fluorouracil; Humans; Inf

1990
Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Female; Fluorouracil; Humans; Inf

1990
A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topi

1987
[Concepts in the prevention and treatment of liver metastases of colorectal cancer by regional chemotherapy].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1988, Volume: 59, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Colonic Ne

1988
A phase III randomized trial of epirubicin versus 5-fluorouracil in metastatic rectal/sigmoid adenocarcinoma.
    American journal of clinical oncology, 1989, Volume: 12, Issue:4

    Topics: Adenocarcinoma; Clinical Trials as Topic; Epirubicin; Fluorouracil; Humans; Neoplasm Metastasis; Ran

1989
[Comparison of surgical therapy and combined irradiation in rectal cancer--first report, effect of irradiation on the tumor. Study Group of Surgical Therapy and Combined Irradiation in Rectal Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Adminis

1989
[Reevaluation of intraluminal fluorouracil chemotherapy as an adjuvant to radical resection of colorectal cancer--results of a randomized trial].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1988, Volume: 10, Issue:5

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Colonic Neoplasms; Combined Modality Therapy;

1988
Prolongation of the disease-free interval in surgically treated rectal carcinoma.
    The New England journal of medicine, 1985, 06-06, Volume: 312, Issue:23

    Topics: Adenocarcinoma; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Follow-U

1985
Prolongation of the disease-free interval in surgically treated rectal carcinoma.
    The New England journal of medicine, 1985, 06-06, Volume: 312, Issue:23

    Topics: Adenocarcinoma; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Follow-U

1985
Prolongation of the disease-free interval in surgically treated rectal carcinoma.
    The New England journal of medicine, 1985, 06-06, Volume: 312, Issue:23

    Topics: Adenocarcinoma; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Follow-U

1985
Prolongation of the disease-free interval in surgically treated rectal carcinoma.
    The New England journal of medicine, 1985, 06-06, Volume: 312, Issue:23

    Topics: Adenocarcinoma; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Follow-U

1985
Prolongation of the disease-free interval in surgically treated rectal carcinoma.
    The New England journal of medicine, 1985, 06-06, Volume: 312, Issue:23

    Topics: Adenocarcinoma; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Follow-U

1985
Prolongation of the disease-free interval in surgically treated rectal carcinoma.
    The New England journal of medicine, 1985, 06-06, Volume: 312, Issue:23

    Topics: Adenocarcinoma; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Follow-U

1985
Prolongation of the disease-free interval in surgically treated rectal carcinoma.
    The New England journal of medicine, 1985, 06-06, Volume: 312, Issue:23

    Topics: Adenocarcinoma; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Follow-U

1985
Prolongation of the disease-free interval in surgically treated rectal carcinoma.
    The New England journal of medicine, 1985, 06-06, Volume: 312, Issue:23

    Topics: Adenocarcinoma; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Follow-U

1985
Prolongation of the disease-free interval in surgically treated rectal carcinoma.
    The New England journal of medicine, 1985, 06-06, Volume: 312, Issue:23

    Topics: Adenocarcinoma; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorouracil; Follow-U

1985
A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Female; Fluorouracil; Humans; Inf

1989
Chemotherapy of large bowel carcinoma--fluorouracil (FU) + hydroxyurea (HU) vs. methyl-CCNU, oncovin, fluorouracil, and streptozotocin (MOF-Strep). An Eastern Cooperative Oncology Group study.
    American journal of clinical oncology, 1985, Volume: 8, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Female; Fluorour

1985
A controlled evaluation of recent approaches to biochemical modulation or enhancement of 5-fluorouracil therapy in colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Drug Evaluat

1985
Systemic infusional chemotherapy for liver metastasis: an improved schedule for 5-fluorouracil.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1986, Volume: 100

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Floxuridine; Fluorouracil

1986
A Northern California Oncology Group randomized trial of leucovorin plus 5-fluorouracil versus sequential methotrexate, 5-fluorouracil, and leucovorin in patients with advanced colorectal cancer who failed treatment with 5-fluorouracil or 5-fluorodeoxyuri
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Drug Administration Sc

1987
A randomized comparison of doxifluridine and fluorouracil in colorectal carcinoma.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Female; Floxurid

1988
Regional infusion of fluoropyrimidines for hepatic metastases of colorectal cancer.
    Pharmaceutisch weekblad. Scientific edition, 1988, Apr-22, Volume: 10, Issue:2

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infu

1988
Systemic cytostatic drug therapy in liver cancer.
    Annales chirurgiae et gynaecologiae. Supplementum, 1986, Volume: 200

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic;

1986
5-Methyltetrahydrofolic acid (MFH4): an effective folate for the treatment of advanced colorectal cancer with 5-FU.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 110

    Topics: Adenocarcinoma; Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination;

1988
Adjuvant therapy for colorectal cancer: the NSABP clinical trials.
    Advances in experimental medicine and biology, 1988, Volume: 244

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Combine

1988
[Randomized study of lentinan on patients with advanced gastric and colorectal cancer. Tohoku Lentinan Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration

1986
[Prospective adjuvant chemotherapy, with mitomycin C plus long-term carmofur in colorectal cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1986, Volume: 32, Issue:3

    Topics: Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; D

1986
Comparison of oral ftorafur and intravenous 5-fluorouracil in patients with advanced cancer of the stomach, colon or rectum.
    Oncology, 1986, Volume: 43, Issue:4

    Topics: Actuarial Analysis; Adenocarcinoma; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Mid

1986
[Cooperative study of surgical adjuvant chemotherapy of colorectal cancer (first report): Investigation of background factors and adverse effects. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:2

    Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Fluorourac

1987
Intraportal chemotherapy in colorectal carcinoma as an adjuvant modality.
    World journal of surgery, 1987, Volume: 11, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; C

1987
Mitomycin C plus carmofur (HCFU) adjuvant chemotherapy for noncuratively resected cases of colorectal carcinoma (interim report).
    The Japanese journal of surgery, 1987, Volume: 17, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy;

1987
Oral ftorafur versus intravenous 5-fluorouracil. A comparative study in patients with colorectal cancer.
    Acta oncologica (Stockholm, Sweden), 1987, Volume: 26, Issue:6

    Topics: Administration, Oral; Adult; Aged; Blood Platelets; Colonic Neoplasms; Female; Fluorouracil; Humans;

1987
[Prospective adjuvant chemotherapy of mitomycin C plus HCFU for colorectal cancer (2d report)--6-year survival after surgery: Tokai Cooperative Study Group of Surgical Adjuvant Chemotherapy].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:4

    Topics: Adjuvants, Immunologic; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colect

1988
Pilot study on the regional treatment of colorectal liver metastases by intermittent arterial ischaemia with degradable starch microspheres and arterial and portal infusion with mitomycin C plus 5-fluorouracil--a clinical trial led by the Gastrointestinal
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Emboliz

1988
Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: results from NSABP protocol R-01.
    Journal of the National Cancer Institute, 1988, Mar-02, Volume: 80, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Th

1988
A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topi

1988
A prospective randomized trial of fluorouracil versus fluorouracil plus cisplatin in the treatment of metastatic colorectal cancer: a Hoosier Oncology Group trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Co

1988
Surgical adjuvant therapy of rectal cancer.
    Seminars in oncology, 1988, Volume: 15, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Clinical Trials as Topic; Combined Modali

1988
Adjuvant therapy in large bowel adenocarcinoma: long-term results of a Southwest Oncology Group Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:6

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine

1988
Adjuvant therapy of colorectal cancer. Why we still don't know.
    JAMA, 1988, Jun-24, Volume: 259, Issue:24

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Neopla

1988
Sequential 5-fluorouracil, methotrexate, and calcium leucovorin in metastatic colorectal cancer.
    Wisconsin medical journal, 1988, Volume: 87, Issue:5

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Col

1988
Systemic therapy of colorectal cancer.
    Wisconsin medical journal, 1988, Volume: 87, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Colonic Neoplas

1988
Chemotherapy of advanced colorectal cancer. A randomized trial of sequential methotrexate and 5-fluorouracil.
    American journal of clinical oncology, 1987, Volume: 10, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Female;

1987
A randomized clinical trial of combination chemotherapy in advanced colorectal cancer.
    American journal of clinical oncology, 1987, Volume: 10, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neopl

1987
Five year results of a randomized trial of adjuvant 5-fluorouracil and levamisole in colorectal cancer.
    The British journal of surgery, 1987, Volume: 74, Issue:7

    Topics: Adult; Aged; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Leukocyte M

1987
Continuous-infusion cisplatin and bolus 5-fluorouracil in colorectal carcinoma.
    Cancer treatment reports, 1987, Volume: 71, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Co

1987
Applications of dose intensity to problems in chemotherapy of breast and colorectal cancer.
    Seminars in oncology, 1987, Volume: 14, Issue:4 Suppl 4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Colonic

1987
Overview of current status and future direction of clinical trials with 5-fluorouracil in combination with folinic acid.
    Cancer treatment reports, 1987, Volume: 71, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Fluorou

1987
A randomized phase I and II study of short-term infusion of high-dose fluorouracil with or without N-(phosphonacetyl)-L-aspartic acid in patients with advanced pancreatic and colorectal cancers.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Colonic Neoplasms; Drug Administration Schedule;

1988
Preliminary analysis of a randomized comparison of 5-fluorouracil versus 5-fluorouracil and high-dose continuous-infusion folinic acid in disseminated colorectal cancer.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Adenocarcinoma; Biological Availability; Colonic Neoplasms; Fluorouracil; Hematopoiesis; Humans; Inf

1987
Clinical studies of biochemical modulation of 5-fluorouracil by leucovorin in patients with advanced colorectal cancer by the North Central Cancer Treatment Group and Mayo Clinic.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Colonic Neoplasms; Dose-Respon

1987
Controlled phase III clinical study of 4-epi-doxorubicin + 5-fluorouracil versus 5-fluorouracil alone in metastatic gastric and rectosigmoid cancer.
    Oncology, 1986, Volume: 43, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Doxorubicin;

1986
Combination chemotherapy (5-fluorouracil, methyl-CCNU, mitomycin C) versus 5-fluorouracil alone for advanced previously untreated colorectal carcinoma. A phase III study of the Piedmont Oncology Association.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; C

1986
Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Ne

1986
5-Fluorouracil chemotherapy and pelvic radiation in the treatment of large bowel cancer. Decreased toxicity in combined treatment with 5-fluorouracil administration through the intraperitoneal route.
    Cancer, 1986, Aug-15, Volume: 58, Issue:4

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule

1986
Clinical trial of cisplatin and intensive course 5-fluorouracil for the treatment of advanced colorectal cancer.
    American journal of clinical oncology, 1986, Volume: 9, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Co

1986
Hepatic arterial ligation and portal vein infusion: a clinical trial by the Gastrointestinal Tract Cancer Group of the European Organization for Research and Treatment of Cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1986, Volume: 100

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Gastrointestinal Neoplasms; Hepatic Arter

1986
Fluorouracil in chemoprophylaxis of colorectal cancer. Results of a controlled clinical trial.
    Diseases of the colon and rectum, 1986, Volume: 29, Issue:11

    Topics: Aged; Clinical Trials as Topic; Colonic Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans;

1986
5-Fluorouracil and folinic acid in the treatment of metastatic colorectal cancer: a randomized comparison. A Southwest Oncology Group Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Ne

1987
Adjuvant immunochemotherapy in colorectal cancer Dukes C.
    Oncology, 1987, Volume: 44, Issue:2

    Topics: Adjuvants, Immunologic; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fema

1987
Pilot trial of prolonged continuous-infusion 5-fluorouracil and weekly cisplatin in advanced colorectal cancer.
    Cancer treatment reports, 1987, Volume: 71, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical

1987
Two randomised phase II trials of intermittent intravenous versus subcutaneous alpha-2 interferon alone (trial 1) and in combination with 5-fluorouracil (trial 2) in advanced colorectal cancer.
    International journal of colorectal disease, 1987, Volume: 2, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Sched

1987
Nonlinear pharmacokinetic characteristics of 5-fluorouracil (5-FU) in colorectal cancer patients.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:4

    Topics: Adult; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Fluorouracil; Half-Life; Humans;

1987
Toxicity studies of adjuvant intravenous versus intraperitoneal 5-FU in patients with advanced primary colon or rectal cancer.
    American journal of clinical oncology, 1986, Volume: 9, Issue:5

    Topics: Colonic Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Fluorouracil; Humans

1986
A randomized trial of oral 5-fluorouracil versus placebo as adjuvant therapy in colorectal cancer Dukes' B and C: results after 5 years observation time.
    The British journal of surgery, 1985, Volume: 72, Issue:2

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Double-Blind Method; Fluorou

1985
A randomized controlled trial of adjuvant portal vein cytotoxic perfusion in colorectal cancer.
    The British journal of surgery, 1985, Volume: 72, Issue:5

    Topics: Aged; Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil;

1985
Clinical trial of adjuvant chemotherapy after surgical resection of colorectal cancer metastatic to the liver.
    Mayo Clinic proceedings, 1985, Volume: 60, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neopl

1985
Prospective, randomized trial of intravenous versus intraperitoneal 5-fluorouracil in patients with advanced primary colon or rectal cancer.
    Surgery, 1985, Volume: 98, Issue:3

    Topics: Adult; Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorourac

1985
Prospective randomized trial of intravenous v intraperitoneal 5-FU in patients with advanced primary colon or rectal cancer.
    Seminars in oncology, 1985, Volume: 12, Issue:3 Suppl 4

    Topics: Adult; Catheters, Indwelling; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Colo

1985
Optimal schedule for 5-fluorouracil chemotherapy. Intermittent bolus or continuous infusion?
    American journal of clinical oncology, 1985, Volume: 8, Issue:5

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusi

1985
Radiation therapy alone or in combination with chemotherapy in the treatment of residual or inoperable carcinoma of the rectum and rectosigmoid or pelvic recurrence following colorectal surgery. Radiation Therapy Oncology Group study (76-16).
    American journal of clinical oncology, 1985, Volume: 8, Issue:2

    Topics: Abscess; Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical T

1985
[Results of phase III study of lentinan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neopl

1985
The need for pilot studies and surgery-only controls in adjuvant therapy trials for large-bowel cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1985, Volume: 98

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topi

1985
Experience with continuous regional chemotherapy and hepatic resection as treatment of hepatic metastases from colorectal primaries. A prospective randomized study.
    Cancer, 1985, Mar-15, Volume: 55, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Colonic Neoplasms; Combined Modality Therapy; F

1985
Combination chemo-radiotherapy for residual, recurrent or inoperable carcinoma of the rectum: E.C.O.G. study (EST 3276).
    International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cobalt Radioisotopes; Combined Modality Therapy; Fem

1985
Adrenal function in patients treated with testosterone and fluorinated pyrimidines.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:2

    Topics: 17-Ketosteroids; Adenocarcinoma; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormon

1968
A pilot study for the evaluation of a new regime of combined therapy for the radical treatment of marginally operable rectal (or colo-rectal) cancer.
    European journal of cancer, 1974, Volume: 10, Issue:9

    Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Evaluation Studies as Topic; Female; Fluor

1974
[Main problems of the method of clinical study of new antineoplastic agents].
    Vestnik Akademii meditsinskikh nauk SSSR, 1966, Volume: 21, Issue:4

    Topics: Antineoplastic Agents; Biopsy; Clinical Trials as Topic; Female; Fluorouracil; Humans; Intestinal Po

1966
Comparison of antimetabolites in the treatment of breast and colon cancer.
    JAMA, 1967, May-29, Volume: 200, Issue:9

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites; Breast Neoplasms; Child; Clinical Trials a

1967
Intraluminal chemotherapy (HN2 or 5-FU) adjuvant to operation for cancer of the colon and rectum. II. Follow-up report of 97 cases.
    Cancer, 1967, Volume: 20, Issue:5

    Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Follow-Up Studies; Humans; M

1967
A five year progress report on the effectiveness of intraluminal chemotherapy (5-fluorouracil) adjuvant to surgery for colorectal cancer.
    American journal of surgery, 1968, Volume: 115, Issue:2

    Topics: Carcinoma; Colonic Neoplasms; Female; Fluorouracil; Humans; Injections, Intravenous; Male; Mechloret

1968
[Tolerance of 5-fluorouracil in intensive treatment with high doses: 4 or 24-hour perfusions?].
    European journal of cancer, 1968, Volume: 4, Issue:6

    Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Fluorouracil; Humans; Injections, Intraven

1968

Other Studies

1625 other studies available for fluorouracil and Cancer of Rectum

ArticleYear
CHEMOTHERAPY IN RECTAL CANCER.
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2021, Volume: 74, Issue:8

    Topics: Disease-Free Survival; Fluorouracil; Humans; Neoplasm Staging; Rectal Neoplasms

2021
Exploring New Approaches for Locally Advanced Gastroesophageal Adenocarcinomas: TNT, Irinotecan, and ctDNA.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 12-01, Volume: 27, Issue:23

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Fluorouracil; Hum

2021
Reduced-dose of doublet chemotherapy combined with anti-EGFR antibodies in vulnerable older patients with metastatic colorectal cancer: Data from the REVOLT study.
    Journal of geriatric oncology, 2022, Volume: 13, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Colonic Neoplasms; Colorectal Neopl

2022
Cost-minimisation analysis of rectal cancer neoadjuvant chemoradiotherapy based on fluoropyrimidines (capecitabine versus 5-fluorouracil).
    European journal of hospital pharmacy : science and practice, 2021, Volume: 28, Issue:Suppl 2

    Topics: Capecitabine; Fluorouracil; Humans; Neoadjuvant Therapy; Rectal Neoplasms; Retrospective Studies

2021
[Drug Approval: Nivolumab plus ipilimumab for patients with MSI -high metastatic colorectal cancer previously treated with 5-fluorouracilchemotherapy].
    Bulletin du cancer, 2022, Volume: 109, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemo

2022
Rapid Initiation of Neoadjuvant Chemoradiotherapy After Diagnosis is Associated With Improved Pathologic Response in Locally Advanced Rectal Cancer.
    American journal of clinical oncology, 2022, 01-01, Volume: 45, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
Neoadjuvant Therapy for Rectal Cancer: Updates From the UNICANCER-PRODIGE 23 Trial.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Fluorouracil; Humans; Irinotecan;

2022
The survival impact of preoperative FOLFOX for resectable locally advanced rectal cancer: the R-NAC-01 study.
    Surgery today, 2022, Volume: 52, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucovorin; Male; Midd

2022
Efficacy of apatinib combined with FOLFIRI in the first-line treatment of patients with metastatic colorectal cancer.
    Investigational new drugs, 2022, Volume: 40, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2022
[A Resected Case of Advanced Lower Rectal Cancer with Neoadjuvant Chemotherapy by FOLFOXIRI plus Cetuximab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2021, Volume: 48, Issue:13

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Fluorouracil; Humans

2021
[A Case of Hyperammonemic Encephalopathy following mFOLFOX6 plus Panitumumab Therapy for Rectal Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2021, Volume: 48, Issue:13

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Fluorouracil; Hum

2021
[A Case of R0 Resection, with Preservation of Bladder Function, of Advanced Rectal Cancer Infiltrating the Bladder with a Single Metastatic Liver Tumor Due to Preoperative Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2021, Volume: 48, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Liver Neopla

2021
[A Long-Survival Case of Lower Rectal Cancer with Unresectable Liver Metastases Treated with FOLFOXIRI plus Bevacizumab(BEV)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2021, Volume: 48, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Fem

2021
Age and comorbidity association with survival outcomes in metastatic colorectal cancer: CALGB 80405 analysis.
    Journal of geriatric oncology, 2022, Volume: 13, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2022
Efficacy and safety analysis of bevacizumab combined with capecitabine in the maintenance treatment of RAS-mutant metastatic colorectal cancer.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Carcinoembryonic Antigen;

2022
A Comparison of Folinic Acid, Fluorouracil and Irinotecan (FOLFIRI) plus Bevacizumab and FOLFIRI plus Aflibercept as Second-line Treatment for Metastatic Colorectal Cancer.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2022, Volume: 34, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2022
[A Case of Rectal Cancer and Multiple Lung Metastases That Had Complete Response Treated by XELOX plus Bevacizumab after Primary Lesion Resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2022, Volume: 49, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Female; Fluorouracil; Hum

2022
Ramucirumab plus triplet chemotherapy as an alternative salvage treatment for patients with metastatic colorectal cancer.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2022, Volume: 121, Issue:10

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms

2022
Long-Term Safety Data on S-1 Administered After Previous Intolerance to Capecitabine-Containing Systemic Treatment for Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2022, Volume: 21, Issue:3

    Topics: Capecitabine; Cardiotoxicity; Colonic Neoplasms; Colorectal Neoplasms; Fluorouracil; Hand-Foot Syndr

2022
Safety and effectiveness of aflibercept in combination with FOLFIRI in Korean patients with metastatic colorectal cancer who received oxaliplatin-containing regimen.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2023
Conjunctivitis associated with capecitabine treatment in a patient with colon cancer: The importance on educating patients into identifying adverse reactions.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:8

    Topics: Aged, 80 and over; Capecitabine; Colonic Neoplasms; Conjunctivitis; Fluorouracil; Humans; Male; Rect

2022
Robotic low anterior resection of rectal metastasis from small bowel adenocarcinoma: A case report.
    Asian journal of endoscopic surgery, 2022, Volume: 15, Issue:4

    Topics: Adenocarcinoma; Aged; Duodenal Neoplasms; Female; Fluorouracil; Humans; Keratin-20; Keratin-7; Leuco

2022
Efficacy and safety of FOLFIRI/aflibercept (FA) in an elderly population with metastatic colorectal cancer (mCRC) after failure of an oxaliplatin-based regimen.
    PloS one, 2022, Volume: 17, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Ne

2022
Benefit from upfront FOLFOXIRI and bevacizumab in BRAFV600E-mutated metastatic colorectal cancer patients: does primary tumour location matter?
    British journal of cancer, 2022, Volume: 127, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2022
Tumor calcification is associated with better survival in metastatic colorectal cancer patients treated with bevacizumab plus chemotherapy.
    Future oncology (London, England), 2022, Volume: 18, Issue:22

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2022
Genetic variants involved in the cGAS-STING pathway predict outcome in patients with metastatic colorectal cancer: Data from FIRE-3 and TRIBE trials.
    European journal of cancer (Oxford, England : 1990), 2022, Volume: 172

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colonic Neopla

2022
Safety and efficacy of irinotecan, oxaliplatin, and capecitabine (XELOXIRI) regimen with or without targeted drugs in patients with metastatic colorectal cancer: a retrospective cohort study.
    BMC cancer, 2022, Jul-21, Volume: 22, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab;

2022
Real-world overall survival of patients receiving cetuximab in later lines of treatment for metastatic colorectal cancer.
    Future oncology (London, England), 2022, Volume: 18, Issue:29

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colonic Neoplasms; Colorect

2022
Capecitabine plus oxaliplatin in the treatment of metastatic colorectal cancer at Tygerberg Hospital: a retrospective study.
    The Pan African medical journal, 2022, Volume: 42

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colonic Neoplasms; Colorectal N

2022
Patient-derived tumor organoids predict responses to irinotecan-based neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer.
    International journal of cancer, 2023, 02-01, Volume: 152, Issue:3

    Topics: Chemoradiotherapy; Fluorouracil; Humans; Irinotecan; Neoadjuvant Therapy; Neoplasms, Second Primary;

2023
MicroRNA-19b Plays a Key Role in 5-Fluorouracil Resistance and Predicts Tumor Progression in Locally Advanced Rectal Cancer Patients.
    International journal of molecular sciences, 2022, Oct-18, Volume: 23, Issue:20

    Topics: Fluorouracil; Humans; MicroRNAs; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Rectal Neoplasms

2022
Aflibercept with FOLFIRI in Japanese patients with metastatic colorectal cancer: results of a post-marketing surveillance.
    International journal of clinical oncology, 2023, Volume: 28, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Coloni

2023
Association between a single nucleotide polymorphism in the R3HCC1 gene and irinotecan toxicity.
    Cancer medicine, 2023, Volume: 12, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2023
A signature of circulating microRNAs predicts the response to treatment with FOLFIRI plus aflibercept in metastatic colorectal cancer patients.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 159

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Circulating MicroRNA; Colonic Neoplasm

2023
Maintenance of angiogenesis inhibition with aflibercept after progression to bevacizumab in metastatic colorectal cancer: real life study in the Valencian community.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023, Volume: 25, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Colore

2023
Could the concomitant use of beta blockers with bevacizumab improve survival in metastatic colon cancer?
    European journal of clinical pharmacology, 2023, Volume: 79, Issue:4

    Topics: Adrenergic beta-Antagonists; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colonic Ne

2023
An integrated multiomics analysis of rectal cancer patients identified POU2F3 as a putative druggable target and entinostat as a cytotoxic enhancer of 5-fluorouracil.
    International journal of cancer, 2023, 07-15, Volume: 153, Issue:2

    Topics: Antineoplastic Agents; Chemoradiotherapy; Fluorouracil; Humans; Multiomics; Neoadjuvant Therapy; Oct

2023
[A Case of Recurrent Rectal Cancer with Acute Lower Extremity Arterial Occlusion during Treatment with Bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2023, Volume: 50, Issue:3

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Fluorourac

2023
Incidence of Disease Recurrence in Patients With Colon and Upper Rectum Adenocarcinoma Stage II and III Receiving Adjuvant Capecitabine Monotherapy: Do Number of Chemotherapy Cycles and Relative Dose Intensity of the Drug Play a Role?
    Clinical colorectal cancer, 2023, Volume: 22, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant

2023
Effect of short-course radiotherapy followed by oxaliplatin-based consolidation chemotherapy on organ preservation in locally advanced rectal cancer.
    International journal of colorectal disease, 2023, Apr-06, Volume: 38, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Consolidation Chemotherapy; Fluor

2023
Maintenance therapy with Fluoropyrimidine and cetuximab or bevacizumab after first line FOLFOX-chemotherapy in metastatic colorectal cancer according to RAS or BRAF
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biological Factors; Cetuximab; Colonic

2023
[A Case of Squamous Cell Carcinoma of the Lower Rectum].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2023, Volume: 50, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Fluorouracil; Humans; Male

2023
Liver cirrhosis following oxaliplatin-based adjuvant chemotherapy for rectal cancer.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascites; Chemotherapy, Adjuva

2023
Impact of prior bevacizumab therapy on the incidence of ramucirumab-induced proteinuria in colorectal cancer: a multi-institutional cohort study.
    International journal of clinical oncology, 2023, Volume: 28, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cohort Studies; Colonic N

2023
Association of Age With Treatment-Related Adverse Events and Survival in Patients With Metastatic Colorectal Cancer.
    JAMA network open, 2023, 06-01, Volume: 6, Issue:6

    Topics: Abdominal Pain; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Female; Fluorouracil; Human

2023
A case report of typhlitis during novel use of ropidoxuridine-capecitabine-radiotherapy for treatment-naïve rectal cancer.
    Cancer chemotherapy and pharmacology, 2023, Volume: 92, Issue:2

    Topics: Adenocarcinoma; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Fem

2023
Short-Course Radiation and Consolidation Chemotherapy for Rectal Cancer-The Rise and Fall of a Treatment Strategy-Rest in Peace.
    Diseases of the colon and rectum, 2023, 10-01, Volume: 66, Issue:10

    Topics: Chemoradiotherapy; Consolidation Chemotherapy; Fluorouracil; Humans; Neoadjuvant Therapy; Rectal Neo

2023
Single-organ pulmonary metastasis is a favorable prognostic factor in metastatic colorectal cancer patients treated with FOLFIRI and vascular endothelial growth factor inhibitors.
    BMC cancer, 2023, Jul-06, Volume: 23, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Colorectal Neoplasm

2023
[Preoperative treatment of rectal cancer-Critical comments on the US-American PROSPECT trial].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:8

    Topics: Fluorouracil; Humans; Neoplasm Staging; Preoperative Care; Rectal Neoplasms; United States

2023
Treatment of metastatic colorectal cancer with BRAF V600E mutation: A multicenter real-world study in China.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2023, Volume: 49, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cetuximab; Colonic Neoplasms; Colorecta

2023
[Neoadjuvant FOLFOX chemotherapy of locally advanced rectal cancer-Results of the PROSPECT study].
    Chirurgie (Heidelberg, Germany), 2023, Volume: 94, Issue:9

    Topics: Fluorouracil; Humans; Neoadjuvant Therapy; Prospective Studies; Rectal Neoplasms; Rectum

2023
Cetuximab as first-line treatment for metastatic colorectal cancer (mCRC): a model-based economic evaluation in Indonesia setting.
    BMC cancer, 2023, Aug-08, Volume: 23, Issue:1

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Col

2023
Role of plasma angiogenesis factors in the efficacy of first-line chemotherapy combined with biologics in RAS wild-type metastatic colorectal cancer: Results from the GI-SCREEN CRC-Ukit study.
    Cancer medicine, 2023, Volume: 12, Issue:18

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biological Prod

2023
Quality of life, effectiveness, and safety of aflibercept plus FOLFIRI in older patients with metastatic colorectal cancer: An analysis of the prospective QoLiTrap study.
    Journal of geriatric oncology, 2023, Volume: 14, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms;

2023
Negative hyperselection of elderly patients with RAS and BRAF wild-type metastatic colorectal cancer receiving initial panitumumab plus FOLFOX or 5-FU/LV.
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 195

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Col

2023
YpN0 rectal cancer patients with sterilized lymph nodes after neoadjuvant chemoradiotherapy are of greater risk of recurrence.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2020, Volume: 52, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, A

2020
Exploration of potential prognostic biomarkers in aflibercept plus FOLFIRI in Japanese patients with metastatic colorectal cancer.
    Cancer science, 2019, Volume: 110, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asian People; Biomarkers, Tumor; Camptothecin; Colon

2019
A rectal cancer organoid platform to study individual responses to chemoradiation.
    Nature medicine, 2019, Volume: 25, Issue:10

    Topics: Animals; Chemoradiotherapy; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasm Me

2019
Poorly differentiated neuroendocrine rectal carcinoma with uncommon immune-histochemical features and clinical presentation with a subcutaneous metastasis, treated with first line intensive triplet chemotherapy plus bevacizumab FIr-B/FOx regimen: an exper
    BMC cancer, 2019, Oct-16, Volume: 19, Issue:1

    Topics: Aged; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2019
[A Case of Lung Metastases from Rectal Cancer Treated for Quite Long with FOLFIRI plus Ramucirumab as a Late Line of Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:10

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemothera

2019
In vitro and in vivo studies on the association of long non‑coding RNAs H19 and urothelial cancer associated 1 with the susceptibility to 5‑fluorouracil in rectal cancer.
    International journal of oncology, 2019, Volume: 55, Issue:6

    Topics: Adult; Aged; Biomarkers, Tumor; Biopsy; Cell Proliferation; Computational Biology; Drug Resistance,

2019
Results of Tri-Modality Therapy for Rectal Cancer in Elderly Patients.
    Anticancer research, 2019, Volume: 39, Issue:11

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemor

2019
Neoadjuvant chemotherapy without radiotherapy for patients with locally advanced rectal cancer. Oncologic outcomes.
    Revista espanola de enfermedades digestivas, 2020, Volume: 112, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Disease-Free S

2020
[A Case of FOLFOXIRI plus BV Therapy Responding to Liver Metastasis of Rectal Cancer with the Portal Venous Tumor Thrombi(Vp4)as Oncologic Emergency].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Hepatectom

2019
Prognostic impact of residual lateral lymph node metastasis after neoadjuvant (chemo)radiotherapy in patients with advanced low rectal cancer.
    BJS open, 2019, Volume: 3, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Disease-Free Surv

2019
Emergence of KRAS p.G13D mutation and acquired resistance to cetuximab in colorectal cancer with vulvar metastasis: A case report.
    Medicine, 2019, Volume: 98, Issue:50

    Topics: Adenocarcinoma; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols

2019
Adjuvant chemotherapy for locally advanced rectal cancer in elderly patients after neoadjuvant chemoradiotherapy and surgery: Toxicity and survival outcomes.
    Medicine, 2020, Volume: 99, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Fem

2020
Modeling rectal cancer to advance neoadjuvant precision therapy.
    International journal of cancer, 2020, 09-01, Volume: 147, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Fluorouracil; Heterografts; Huma

2020
FOLFOX and capecitabine-induced hepatic granuloma mimicking metastasis in a rectal cancer patient.
    BMJ case reports, 2020, Mar-04, Volume: 13, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemi

2020
[Two Cases of Advanced Colorectal Cancer Achieving Complete Response by FOLFOXIRI plus Bevacizumab-A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms;

2019
[A Case of Long-Term Clinical Complete Response after Chemotherapy for Locally Advanced Rectal Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colostomy; Fluorouracil; Humans; Leucovorin; Male; R

2019
Improved Outcomes for Responders After Treatment with Induction Chemotherapy and Chemo(re)irradiation for Locally Recurrent Rectal Cancer.
    Annals of surgical oncology, 2020, Volume: 27, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Femal

2020
Metformin as an Alternative Radiosensitizing Agent to 5-Fluorouracil During Neoadjuvant Treatment for Rectal Cancer.
    Diseases of the colon and rectum, 2020, Volume: 63, Issue:7

    Topics: Animals; Case-Control Studies; Chemoradiotherapy; Combined Modality Therapy; Female; Fluorouracil; H

2020
ADJUVANT CHEMOTHERAPY IN LOCALLY ADVANCED RECTAL CANCER: DECIDING ON THE OPTIMAL STRATEGY.
    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 2020, Volume: 72, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemotherapy, Adjuvant; Disease-Free Survival

2020
RHBDD2 overexpression promotes a chemoresistant and invasive phenotype to rectal cancer tumors via modulating UPR and focal adhesion genes.
    Biochimica et biophysica acta. Molecular basis of disease, 2020, 08-01, Volume: 1866, Issue:8

    Topics: Antimetabolites, Antineoplastic; Caco-2 Cells; Cell Adhesion; Cell Movement; Cell Proliferation; Dru

2020
[Long-Term Survival of a Patient with Advanced Recurrent Rectal Cancer Treated with a Multidisciplinary Therapy including Five Operations-A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Female; Fluorouracil; Humans; Ne

2020
[Bladder-Sparing Surgery with Preoperative Chemotherapy for Rectal Cancer with Urinary Bladder Involvement-A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Male; Neoadj

2020
[Locally Advanced Rectal Cancer Curatively Resected after Modified FOLFOXIRI plus Bevacizumab Chemotherapy-A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Fluorouracil; Human

2020
[A Case of Malignant Lymphoma Undergoing HAI Treatment for Multiple Liver Metastases of Carcinoid That Appeared about Nine Years after Resection of Rectal Carcinoid with Liver Metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Chemoembolization, Therapeuti

2020
MRI T2-weighted sequences-based texture analysis (TA) as a predictor of response to neoadjuvant chemo-radiotherapy (nCRT) in patients with locally advanced rectal cancer (LARC).
    La Radiologia medica, 2020, Volume: 125, Issue:12

    Topics: Adult; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Female; Fluoroura

2020
TRIBE2 results and toxicity - Authors' reply.
    The Lancet. Oncology, 2020, Volume: 21, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Fluorouracil; Humans; Leu

2020
Neoadjuvant Immunotherapy-Based Systemic Treatment in MMR-Deficient or MSI-High Rectal Cancer: Case Series.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2020, Volume: 18, Issue:7

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2020
A Diagnostic Biopsy-Adapted Immunoscore Predicts Response to Neoadjuvant Treatment and Selects Patients with Rectal Cancer Eligible for a Watch-and-Wait Strategy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 10-01, Volume: 26, Issue:19

    Topics: Aged; Biopsy; CD3 Complex; CD8-Positive T-Lymphocytes; Cell Lineage; Cell Proliferation; Disease-Fre

2020
Feasibility of relatively low neoadjuvant radiation doses for locally advanced rectal cancer: A propensity score-matched analysis.
    Cancer reports (Hoboken, N.J.), 2019, Volume: 2, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Disease-Free Surv

2019
Portal Vein Thrombosis in Metastatic Colorectal Cancer During FOLFIRI-bevacizumab Chemotherapy Successfully Treated with Apixaban.
    Internal medicine (Tokyo, Japan), 2021, Jan-01, Volume: 60, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasm

2021
5-Fluorouracil-induced encephalopathy.
    Cleveland Clinic journal of medicine, 2020, Aug-31, Volume: 87, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Female; Fluorouracil; Humans;

2020
Disturbance of consciousness due to hyperammonemia and lactic acidosis during mFOLFOX6 regimen: Case report.
    Medicine, 2020, Aug-14, Volume: 99, Issue:33

    Topics: Acidosis, Lactic; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protoc

2020
Real-world outcomes for neoadjuvant capecitabine versus infusional 5-fluorouracil in the treatment of locally advanced rectal cancer.
    Internal medicine journal, 2021, Volume: 51, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Australia; Capecitabine; Fluorouracil; Humans; Neoad

2021
A Prospective, Single-arm, Multicenter Trial of Diverting Stoma Followed by Neoadjuvant Chemotherapy Using mFOLFOX6 for Obstructive Colon Cancer: YCOG 1305 (PROBE Study).
    Annals of surgery, 2022, 07-01, Volume: 276, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Fluoroura

2022
The Older Adults With Rectal Cancer-Does Age Matter?: A Single-center Experience.
    American journal of clinical oncology, 2020, 12-01, Volume: 43, Issue:12

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Comorbidity; Female; Fluorouracil; Hospitalization; H

2020
Even a partial pathological response is associated with lower relapse rates in patients with operable rectal cancer undergoing neoadjuvant chemotherapy.
    Journal of surgical oncology, 2021, Volume: 123, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase

2021
Total Neoadjuvant Treatment for Rectal Cancer: Preliminary Experience.
    The American surgeon, 2021, Volume: 87, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Female; Fl

2021
Prognostic Value of Pretreatment Serum CA199 in Patients with Locally Advanced Rectal Cancer Treated with CRT Followed by TME with Normal Pretreatment Carcinoembryonic Antigen Levels.
    Digestive surgery, 2021, Volume: 38, Issue:1

    Topics: Adenocarcinoma; Aged; Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Agents; Antineoplasti

2021
Organ Preservation in the Treatment of Stage II and III Rectal Cancer.
    Diseases of the colon and rectum, 2020, Volume: 63, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Colectomy;

2020
[A Case of Locally Advanced Rectal Cancer Treated by Robot Assisted Intersphincteric Resection after Neoadjuvant Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2021, Volume: 48, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucovorin; Neoa

2021
[Two Cases of Resectable Liver Metastasis from Colorectal Cancer with Pathological Complete Response after Neoadjuvant Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Female; Flu

2020
[Laparoscopic Abdominoperineal Resection Following Intensive Chemotherapy for Stage Ⅳ Rectal Cancer with Unresectable Metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Fluorouracil; Hum

2020
[A Case of Advanced Rectal Cancer Successfully Treated with Preoperative Radiochemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:13

    Topics: Adenocarcinoma; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy

2020
Hepatectomy for liver metastasis from rectal cancer in a patient with mitochondrial disease.
    BMJ case reports, 2021, Feb-05, Volume: 14, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Diabetes Mellitus, Type 2; Fema

2021
Initial experience of preoperative short-course radiotherapy followed by oxaliplatin-based consolidation chemotherapy for locally advanced rectal cancer.
    International journal of colorectal disease, 2021, Volume: 36, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Consolidation Chemot

2021
Beneficial effects of modulated electro-hyperthermia during neoadjuvant treatment for locally advanced rectal cancer.
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2021, Volume: 38, Issue:1

    Topics: Fluorouracil; Humans; Hyperthermia; Hyperthermia, Induced; Middle Aged; Neoadjuvant Therapy; Neoplas

2021
Locally advanced rectal adenocarcinoma: Treatment sequences, intensification, and rectal organ preservation.
    CA: a cancer journal for clinicians, 2021, Volume: 71, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoembryonic

2021
Safety and efficacy of preoperative mFOLFOX6 regimen chemotherapy for locally resectable advanced rectal cancer.
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2021, Jan-28, Volume: 46, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; China; Fluorouracil; Humans; Neoadjuvant Therapy; Ne

2021
Effective chemotherapy and targeted therapy supplemented with stereotactic radiotherapy of a patient with metastatic colon cancer following renal transplantation: a case report.
    Journal of medical case reports, 2021, Mar-20, Volume: 15, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Colorectal Neoplasms; Diabetes Mell

2021
Risk factors for sexual dysfunction after rectal cancer surgery in 948 consecutive patients: A prospective cohort study.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2021, Volume: 47, Issue:8

    Topics: Adenocarcinoma; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Ch

2021
Hyperammonemia-induced impaired consciousness following mFOLFOX6 therapy in a patient with recurrent rectal cancer.
    International journal of clinical pharmacology and therapeutics, 2021, Volume: 59, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Consciousness; Female; Fluorouracil; Humans; Hyperam

2021
Are we already in the era of total neoadjuvant treatment for rectal cancer?
    The Lancet. Oncology, 2021, Volume: 22, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Fluorouracil; Humans; Irinotecan;

2021
Prognostic impact of additive chemotherapy after curative resection of metachronous colorectal liver metastasis: a single-centre retrospective study.
    BMC cancer, 2021, May-03, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capeci

2021
Improved response rate in patients with prognostically poor locally advanced rectal cancer after treatment with induction chemotherapy and chemoradiotherapy when compared with chemoradiotherapy alone: A matched case-control study.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2021, Volume: 47, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Case-Control Studie

2021
Real-world Patterns of Adjuvant Chemotherapy Following Neoadjuvant Chemoradiation for Patients With Resected Rectal Adenocarcinoma.
    American journal of clinical oncology, 2021, 08-01, Volume: 44, Issue:8

    Topics: Adenocarcinoma; Alberta; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Fem

2021
Concomitant Use of Proton Pump Inhibitors With Capecitabine Based Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer: Is it Safe?
    American journal of clinical oncology, 2021, 09-01, Volume: 44, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemor

2021
Tumor Volume as Predictor of Pathologic Complete Response Following Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer.
    American journal of clinical oncology, 2021, 09-01, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Capecitabine; Chemoradiotherapy; Female; Fluorouracil; Huma

2021
Relation between body composition and severe diarrhea in patients treated with preoperative chemoradiation with capecitabine for rectal cancer: a single-centre cohort study.
    BMC gastroenterology, 2021, Aug-04, Volume: 21, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Body Composition; Capecitabine; Cohort Studies; Deox

2021
Does chronomodulated radiotherapy improve pathological response in locally advanced rectal cancer?
    Chronobiology international, 2017, Volume: 34, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Circ

2017
Oncological Outcomes of Lateral Pelvic Lymph Node Metastasis in Rectal Cancer Treated With Preoperative Chemoradiotherapy.
    Diseases of the colon and rectum, 2017, Volume: 60, Issue:5

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy; Colectomy; Female; Fluorouracil;

2017
Gene expression levels of gamma-glutamyl hydrolase in tumor tissues may be a useful biomarker for the proper use of S-1 and tegafur-uracil/leucovorin in preoperative chemoradiotherapy for patients with rectal cancer.
    Cancer chemotherapy and pharmacology, 2017, Volume: 79, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Che

2017
[A Case Report on a Successful Resection after FOLFIRI plus Cetuximab Therapy for Unresectable Colorectal Cancer with Multiple Liver Metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2017, Volume: 44, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colectomy; Combined M

2017
[A Case of Effective Chemoradiotherapy Using mFOLFOX6 for Locally Advanced Rectal Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2017, Volume: 44, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Drug Combinations;

2017
The Role of Concomitant Radiation Boost in Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer.
    Anticancer research, 2017, Volume: 37, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Fe

2017
Continuous Effect of Radial Resection Margin on Recurrence and Survival in Rectal Cancer Patients Who Receive Preoperative Chemoradiation and Curative Surgery: A Multicenter Retrospective Analysis.
    International journal of radiation oncology, biology, physics, 2017, 07-01, Volume: 98, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents; Capecit

2017
Prognostic significance of tumour regression grade after neoadjuvant chemoradiotherapy for a cohort of patients with locally advanced rectal cancer: an 8-year retrospective single-institutional study.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2017, Volume: 19, Issue:7

    Topics: Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Disease-Free Survival; Female; Fluorouraci

2017
Relationship Between Expression of Proteins ERCC1, ERCC2, and XRCC1 and Clinical Outcomes in Patients with Rectal Cancer Treated with FOLFOX-Based Preoperative Chemoradiotherapy.
    World journal of surgery, 2017, Volume: 41, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; DNA-Bindin

2017
Cutaneous Drug REactions: Annular, polycyclic erythematous exanthema in an oncology patient.
    European journal of dermatology : EJD, 2017, Jun-01, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol

2017
Role of adjuvant chemotherapy in locally advanced rectal cancer with ypT0-3N0 after preoperative chemoradiation therapy and surgery.
    BMC cancer, 2017, Sep-02, Volume: 17, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Modality Therapy

2017
Comparing pathological complete response rate using oral capecitabine versus infusional 5-fluorouracil with preoperative radiotherapy in rectal cancer treatment.
    ANZ journal of surgery, 2018, Volume: 88, Issue:1-2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine;

2018
[A Case of Bilateral Lymph Node Metastases of Rectal Cancer Treated with Chemotherapy and Surgery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2017, Volume: 44, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Combined Modality Therapy; Fluoro

2017
Outcomes of patients with abdominoperineal resection (APR) and low anterior resection (LAR) who had very low rectal cancer.
    Medicine, 2017, Volume: 96, Issue:43

    Topics: Anal Canal; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Digestive System Surgi

2017
Outcome of neoadjuvant chemoradiation in MRI staged locally advanced rectal cancer: Retrospective analysis of 123 Chinese patients.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2018, Volume: 117, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Capecitabine; Chemoradiotherapy; Female; Fluorouracil; Humans; Magnetic

2018
The Role of Oxaliplatin in Chemoradiotherapy for Rectal Cancer.
    Asia-Pacific journal of clinical oncology, 2017, Volume: 13, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant

2017
Outcomes of neoadjuvant chemoradiotherapy followed by total mesorectal excision surgery for locally advanced rectal cancer: a single-institution experience.
    Singapore medical journal, 2018, Volume: 59, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biom

2018
Authors' reply to "Rectal sparing approach after preoperative radio- and/or chemotherapy (RESARCH) in patients with rectal cancer: potential pitfalls of a multicentre observational study".
    Techniques in coloproctology, 2018, Volume: 22, Issue:2

    Topics: Fluorouracil; Humans; Neoplasm Staging; Preoperative Care; Rectal Neoplasms; Rectum

2018
[A Case of Laparoscopic Surgery Performed for Locally Advanced Rectal Cancer Suspected of Invasion to Prostate].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2017, Volume: 44, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Laparoscopy; Leucovorin; Male;

2017
[Experience of Ramucirumab plus FOLFIRI as Second-Line Treatment for Metastatic Colorectal Cancer in Our Hospital].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2017, Volume: 44, Issue:12

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2017
Could early tumour volume changes assessed on morphological MRI predict the response to chemoradiation therapy in locally-advanced rectal cancer?
    Clinical radiology, 2018, Volume: 73, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2018
Adoption of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer.
    JAMA oncology, 2018, 06-14, Volume: 4, Issue:6

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherap

2018
Prognostic Impact of R0 Resection and Targeted Therapy for Colorectal Cancer with Synchronous Peritoneal Metastasis.
    Annals of surgical oncology, 2018, Volume: 25, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab;

2018
Does Adjuvant Chemotherapy After Preoperative Chemoradiation Improve Overall Survival in Patients With Rectal Cancer?
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:5

    Topics: Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Survival; Fluorouracil; Humans; Radiotherapy

2018
Effect of Comorbidities in Stage II/III Colorectal Cancer Patients Treated With Surgery and Neoadjuvant/Adjuvant Chemotherapy: A Single-Center, Observational Study.
    Clinical colorectal cancer, 2018, Volume: 17, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemot

2018
[A Case of Colon Cancer with Brain, Liver and Lung Metastasis Successfully Treated with Bevacizumab plus Xelox Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Capecitabine; Deoxycyt

2018
Tumor response after long interval comparing 5x5Gy radiation therapy with chemoradiation therapy in rectal cancer patients.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2018, Volume: 44, Issue:7

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Agents; Carcinoma, Signet Ring

2018
[IDEA study (International Duration Evaluation of Adjuvant Chemotherapy) for patients with stage III colon cancer: Possibility of reducing to 3 months treatment for 60% of the patients!]
    Bulletin du cancer, 2018, Volume: 105, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Clinical Trial

2018
Management of Locoregional Rectal Cancer.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2018, Volume: 16, Issue:5S

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Disease-Free Survival; Fluorourac

2018
Therapeutic effects of oxaliplatin-based neoadjuvant chemotherapy and chemoradiotherapy in patients with locally advanced rectal cancer: a single-center, retrospective cohort study.
    World journal of surgical oncology, 2018, Jun-05, Volume: 16, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemoradiotherapy, A

2018
[Research progress of neoadjuvant therapy for locally advanced rectal cancer].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2018, Jun-25, Volume: 21, Issue:6

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant

2018
[A Case of Rectal Cancer and Multiple Liver Metastases Treated Using mFOLFOX and Bevacizumab under Maintenance Dialysis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Fluorouracil; Glomerulonephritis, IGA;

2018
[A Case Describing Treatment with FOLFIRI plus Bevacizumab after a Self-Expandable Metallic Stent Placement for Local Recurrence].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Fluorouracil; Humans; Int

2018
Radiation therapy damages external anal sphincter and perineal muscle floor.
    Journal of surgical oncology, 2018, Volume: 118, Issue:4

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Arterioles; Collagen; Dilatation, Pathol

2018
Identification of Predictors of Recurrence in Patients with Lower Rectal Cancer Undergoing Neoadjuvant Chemotherapy: A Direct Comparison of Short-Course and Long-Course Chemoradiotherapy.
    Oncology, 2019, Volume: 96, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; C

2019
[Primary Small Bowel Tumor with Simultaneous Lung Metastases from Rectal Cancer - A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Intestinal Neoplasms;

2018
Adjuvant Chemotherapy in Rectal Cancer Patients Treated With Preoperative Chemoradiation and Total Mesorectal Excision: A Multicenter and Retrospective Propensity-Score Matching Study.
    International journal of radiation oncology, biology, physics, 2019, 02-01, Volume: 103, Issue:2

    Topics: Aged; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluoro

2019
C-Reactive Protein Level Predicts Survival Outcomes in Rectal Cancer Patients Undergoing Total Mesorectal Excision After Preoperative Chemoradiation Therapy.
    Annals of surgical oncology, 2018, Volume: 25, Issue:13

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; C-Reactive Pr

2018
[A Case of a Patient with Rectum Cancer with Multiple Metastases, Who Was Able to Undergo Conversion Therapy Using Alternating mFOLFOX6 and FOLFIRI Regimens in Combination with Alternating Cetuximab and Bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Female;

2018
Complete pathological response following neoadjuvant FOLFOX chemotherapy in BRCA2-mutant locally advanced rectal cancer: a case report.
    BMC cancer, 2018, Dec-14, Volume: 18, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; BRCA2 Protein; Fluorouracil; Humans; Leucovor

2018
Impact of pelvic bone marrow irradiation on the hematological toxicity of subsequent chemotherapy in rectal cancer.
    Neoplasma, 2019, Mar-05, Volume: 66, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chemoradiotherapy; Fluorouracil; Humans

2019
Rechallenge capecitabine after fluoropyrimidine-induced cardiotoxicity in rectal cancer: A case report.
    Medicine, 2019, Volume: 98, Issue:2

    Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Capecitabine; Cardiotoxicity; Combined Modal

2019
[A Case of Complete Response to Lower Rectal Cancer after Preoperative Chemotherapy with CapeOX Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Fluorouracil; Humans; Male; Neoa

2018
[A Case of Resistance to Systemic Therapy in Hypermutation of Colorectal Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Humans; Le

2018
Rapidly progressing ulcer and a urine drainage bag.
    Dermatology online journal, 2018, Nov-15, Volume: 24, Issue:11

    Topics: Adrenal Cortex Hormones; Aged; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemothera

2018
Refining the Use of Adjuvant Oxaliplatin in Clinical Stage II or III Rectal Adenocarcinoma.
    The oncologist, 2019, Volume: 24, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; C

2019
Variation in the Thoroughness of Pathologic Assessment and Response Rates of Locally Advanced Rectal Cancers After Chemoradiation.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2019, Volume: 23, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cohort Studies; F

2019
[Curative Transanal Resection after Neoadjuvant Chemotherapy for Lower Rectal Cancer-A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Middle Aged; Neoadjuva

2019
[Two Cases of Locally Advanced Rectal Cancer and Lower Rectal Cancer Resected Successfully That Enabled Anus Preservation after Preoperative Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:1

    Topics: Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Male; Middle

2019
Thymidylate synthase gene polymorphism predicts disease free survival in stage II-III rectal adenocarcinoma patients receiving adjuvant 5-FU-based chemotherapy.
    Chinese clinical oncology, 2019, Volume: 8, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil; Hu

2019
Pathological complete response may underestimate distant metastasis in locally advanced rectal cancer following neoadjuvant chemoradiotherapy and radical surgery: Incidence, metastatic pattern, and risk factors.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2019, Volume: 45, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain N

2019
Survival Outcomes After Surgical Management of the Primary Tumor With and Without Radiotherapy for Metastatic Rectal Adenocarcinoma: A National Cancer Database (NCDB) Analysis.
    Clinical colorectal cancer, 2019, Volume: 18, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Pro

2019
[Locally Advanced Rectal Cancer Presenting with Perforation That Was Successfully Resected after Preoperative Chemotherapy with mFOLFOX6 plus Panitumumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucovorin; Orga

2019
Reply to C. Kersten et al and D.A. Parikh et al.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019, 06-20, Volume: 37, Issue:18

    Topics: Cetuximab; Fluorouracil; Humans; Leucovorin; Oxaliplatin; Rectal Neoplasms

2019
Induction Chemotherapy Reduces Patient-reported Toxicities During Neoadjuvant Chemoradiation with Intensity Modulated Radiotherapy for Rectal Cancer.
    Clinical colorectal cancer, 2019, Volume: 18, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, A

2019
Neutrophil-to-Lymphocyte Ratio in Rectal Cancer-Novel Biomarker of Tumor Immunogenicity During Radiotherapy or Confounding Variable?
    International journal of molecular sciences, 2019, May-17, Volume: 20, Issue:10

    Topics: Aged; Biomarkers, Tumor; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil; H

2019
Interleukin-17A polymorphisms predict the response and development of tolerance to FOLFOX chemotherapy in colorectal cancer treatment.
    Cancer gene therapy, 2020, Volume: 27, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cross-Sectional Stud

2020
[A Case of a Patient with Locally Recurrent Rectal Cancer Who Underwent Surgical Resection after Chemotherapy with FOLFOXIRI plus Bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Female; Fluorouracil; Hum

2019
ARID3A Positivity Correlated With Favorable Prognosis in Patients With Residual Rectal Cancer After Neoadjuvant Chemoradiotherapy.
    Anticancer research, 2019, Volume: 39, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Chemoradiotherapy, Adjuvant; Disease-Free Survival; DNA-Binding Prot

2019
Achieving a Complete Clinical Response After Neoadjuvant Chemoradiation That Does Not Require Surgical Resection: It May Take Longer Than You Think!
    Diseases of the colon and rectum, 2019, Volume: 62, Issue:7

    Topics: Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Female; Fluorouracil; Humans; Ma

2019
[A Case of Curatively Resected Rectosigmoid Colon Cancer That Invaded the Urinary Bladder after Neoadjuvant Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Male; Neoadj

2019
Effects of metformin and phenformin on apoptosis and epithelial-mesenchymal transition in chemoresistant rectal cancer.
    Cancer science, 2019, Volume: 110, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Movement;

2019
Successful treatment of unresectable advanced rectal cancer with liver metastases by hemostasis re-irradiation of the rectal cancer and palliative low-dose whole-liver radiation therapy: a case report.
    Clinical journal of gastroenterology, 2020, Volume: 13, Issue:1

    Topics: Abdominal Pain; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothe

2020
Pretreatment blood biomarkers predict pathologic responses to neo-CRT in patients with locally advanced rectal cancer.
    Future oncology (London, England), 2019, Volume: 15, Issue:28

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Capecitabine; Carcin

2019
[A case with multiple liver metastases from rectal cancer responding completely to FOLFOX for a long duration without exacerbation of peripheral neuropathy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Fluorouracil; Humans; Leucovorin; Live

2013
Prognosis factors for recurrence in patients with locally advanced rectal cancer preoperatively treated with chemoradiotherapy and adjuvant chemotherapy.
    Diseases of the colon and rectum, 2013, Volume: 56, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Carcinoma; Chemoradiotherapy; C

2013
Novel single-nucleotide polymorphism markers predictive of pathologic response to preoperative chemoradiation therapy in rectal cancer patients.
    International journal of radiation oncology, biology, physics, 2013, Jun-01, Volume: 86, Issue:2

    Topics: Alleles; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Capecitabine;

2013
Routine defunctioning stoma after chemoradiation and total mesorectal excision: a single-surgeon experience.
    World journal of gastroenterology, 2013, Mar-21, Volume: 19, Issue:11

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Colostomy; Dose Fractiona

2013
Update: NCCN colon and rectal cancer clinical practice guidelines.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2004, Volume: 2 Suppl 3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2004
Modern multidisciplinary treatment of rectal cancer based on staging with magnetic resonance imaging leads to excellent local control, but distant control remains a challenge.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine

2013
[Tolerance and efficacy of preoperative radiation therapy for elderly patients treated for rectal cancer].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2013, Volume: 17, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Chemotherapy, Adjuvant; Dose Fractionation, Radiatio

2013
[Immediate results of complex treatment of resectable rectal neoplasms of distal localization].
    Klinichna khirurhiia, 2013, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Case-Control Studies; Disease-Free Survival; Female; Fluorour

2013
Histopathological regression grading matches excellently with local and regional spread after neoadjuvant therapy of rectal cancer.
    Pathology, research and practice, 2013, Volume: 209, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Chi-Square Distributio

2013
Neoadjuvant-intensified treatment for rectal cancer: time to change?
    World journal of gastroenterology, 2013, May-28, Volume: 19, Issue:20

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2013
Oxaliplatin-induced acquired long QT syndrome with torsades de pointes and myocardial injury in a patient with dilated cardiomyopathy and rectal cancer.
    Journal of the Chinese Medical Association : JCMA, 2013, Volume: 76, Issue:8

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathy, Dilated

2013
Feasibility of an adaptive strategy in preoperative radiochemotherapy for rectal cancer with image-guided tomotherapy: boosting the dose to the shrinking tumor.
    International journal of radiation oncology, biology, physics, 2013, Sep-01, Volume: 87, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Dose Fractionation,

2013
Evolving role of neoadjuvant therapy in rectal cancer.
    Current treatment options in oncology, 2013, Volume: 14, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Com

2013
Therapy-related acute promyelocytic leukemia after chemoradiotherapy with capecitabine for rectal adenocarcinoma.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:3

    Topics: Antimetabolites, Antineoplastic; Bone Marrow; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Leu

2014
[A case of necrotizing fasciitis developed in a patient with recurrent rectal cancer treated with chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cape

2013
[Successful management using laparoscopic splenectomy for splenomegaly and thrombocytopenia caused by oxaliplatin-based chemotherapy for advanced rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fatal Outcome; Fluorouracil; Humans; Laparoscopy; Le

2013
[Successful treatment of a patient using mFOLFOX6 after laparoscopic surgery for rectal cancer with peritoneal dissemination].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Lap

2013
Preoperative long course chemoirradiation in a developing country for rectal carcinoma: Kuala Lumpur hospital experience.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2013
Clinical outcome of neoadjuvant chemoradiation therapy with oxaliplatin and capecitabine or 5-fluorouracil for locally advanced rectal cancer.
    Journal of surgical oncology, 2013, Volume: 108, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothe

2013
The preliminary experience in simultaneous treatment of rectal cancer and synchronous liver metastases with laparoscopy.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2013, Volume: 24, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Anastomosis, Surgical; Antineoplastic Combined Chemotherapy

2013
Aggressive strategy for the treatment of synchronous metastatic anal squamous cell carcinoma.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplat

2013
Mutational and clinical predictors of pathologic complete response in the treatment of locally advanced rectal cancer.
    Journal of gastrointestinal cancer, 2014, Volume: 45, Issue:1

    Topics: Adenocarcinoma; Adenomatous Polyposis Coli Protein; Adolescent; Adult; Aged; Aged, 80 and over; Anti

2014
[Adjuvant chemotherapy for patients with rectal cancer].
    Ugeskrift for laeger, 2013, Sep-09, Volume: 175, Issue:37

    Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Fluorouracil; Humans; Magnetic Resonance Imaging; Pos

2013
Long-term quality-of-life after neoadjuvant short-course radiotherapy and long-course radiochemotherapy for locally advanced rectal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 108, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Chemoradiotherapy; Cross-Sectional Studies; Disease-Free Survival; F

2013
Cumulative incidence of permanent stoma after sphincter preserving low anterior resection of mid and low rectal cancer.
    Diseases of the colon and rectum, 2013, Volume: 56, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Anastomosis, Surgical; Anastomotic Leak;

2013
[Use of hydrogel tissues with 5-fluorouracil and sodium alginate, "COLETEX-5-FTUR," for radiomodification in cancer patients receiving radiation therapy].
    Voprosy onkologii, 2013, Volume: 59, Issue:4

    Topics: Adult; Aged; Alginates; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fluorouracil; Glucuronic A

2013
Acute effects of pelvic irradiation on the adult uterus revealed by dynamic contrast-enhanced MRI.
    The British journal of radiology, 2013, Volume: 86, Issue:1031

    Topics: Adult; Antimetabolites, Antineoplastic; Chemoradiotherapy; Contrast Media; Endometrium; Female; Fluo

2013
Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications.
    BMC surgery, 2013, Sep-30, Volume: 13

    Topics: Adenocarcinoma; Aged; Anastomotic Leak; Antineoplastic Agents; Antineoplastic Combined Chemotherapy

2013
Cancer-initiating cells derived from human rectal adenocarcinoma tissues carry mesenchymal phenotypes and resist drug therapies.
    Cell death & disease, 2013, Oct-03, Volume: 4

    Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2013
Metastatic lymph node ratio in stage III rectal carcinoma is a valuable prognostic factor even with less than 12 lymph nodes retrieved: a prospective study.
    American journal of surgery, 2014, Volume: 207, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Chemoradiotherapy; Colonoscop

2014
The prognostic value of tumour regression grade following neoadjuvant chemoradiation therapy for rectal cancer.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2014, Volume: 16, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy;

2014
Impact of chemotherapy on normal tissue complication probability models of acute hematologic toxicity in patients receiving pelvic intensity modulated radiation therapy.
    International journal of radiation oncology, biology, physics, 2013, Dec-01, Volume: 87, Issue:5

    Topics: Aged; Antineoplastic Agents; Anus Neoplasms; Bone Marrow; Chemoradiotherapy; Cisplatin; Drug Adminis

2013
Comparison of two preoperative chemoradiotherapy regimens for locally advanced rectal cancer: capecitabine alone versus capecitabine plus irinotecan.
    Radiation oncology (London, England), 2013, Nov-04, Volume: 8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2013
C-reactive protein as predictor of recurrence in patients with rectal cancer undergoing chemoradiotherapy followed by surgery.
    Anticancer research, 2013, Volume: 33, Issue:11

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Proto

2013
[A case of hepatitis B virus reactivation in a patient with prior resolved hepatitis B infection during bevacizumab plus FOLFIRI treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:11

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab

2013
Evaluation of capecitabine and oxaliplatin administered prior to and then concomitant to radiotherapy in high risk locally advanced rectal cancer.
    Journal of surgical oncology, 2014, Volume: 109, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; China;

2014
Preoperative chemoradiation with or without induction oxaliplatin plus 5-fluorouracil in locally advanced rectal cancer. Long-term outcome analysis.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2014, Volume: 190, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Chemorad

2014
[Efficacy and safety of bevacizumab (BEV) plus chemotherapeutic agents in the treatment of metastatic colorectal cancer, mCRC].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2013, Volume: 35, Issue:8

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Che

2013
[Value of postoperative adjuvant chemotherapy in locally advanced rectal cancer patients with ypT1-4N0 after neo-adjuvant chemoradiotherapy].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2013, Volume: 35, Issue:9

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Pro

2013
[A case of metastatic colorectal cancer with hyperammonemic encephalopathy induced by 5-FU in a patient continuously treated with XELOX therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:13

    Topics: Amino Acids, Branched-Chain; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases, Metabol

2013
[A case of advanced rectal cancer treated with leucovorin, fluorouracil, and oxaliplatin plus panitumumab preoperative chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; F

2013
[A case of pathological complete response with neoadjuvant mFOLFOX6 chemotherapy for advanced lower rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovor

2013
[A case of successful radical resection of rectal cancer with neo-adjuvant chemoradiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Fluorouracil; Humans; Leucovorin;

2013
[Neoadjuvant chemoradiotherapy with capecitabine and oxaliplatin for the treatment of locally advanced lower rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine

2013
[A case of good response in a rectal cancer patient with decreased dihydropyrimidine dehydrogenase activity because of strict control of the 5-fluorouracil dose].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Dihydrouracil Dehydrogenase (NADP); Fluo

2013
[A case of rectal endocrine cell carcinoma treated by laparoscopic assisted intersphincteric resection after neoadjuvant chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Endocrine Cells; Fluorouraci

2013
[Two cases of locally advanced colorectal cancer curatively resected after neoadjuvant chemotherapy with 5-fluorouracil, leucovorin, and oxaliplatin plus panitumumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans

2013
[A case of locally advanced colorectal cancer with abscess responding to 5-fluorouracil, leucovorin, and oxaliplatin plus bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Abscess; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2013
Chemoradiotherapy response in recurrent rectal cancer.
    Cancer medicine, 2014, Volume: 3, Issue:1

    Topics: Adult; Aged; Chemoradiotherapy; Fluorouracil; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imag

2014
Oxaliplatin and capecitabine concomitant with neoadjuvant radiotherapy and extended to the resting period in high risk locally advanced rectal cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2014, Volume: 190, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; China;

2014
Complete pathological response (ypT0N0M0) after preoperative chemotherapy alone for stage IV rectal cancer.
    BMC surgery, 2014, Jan-17, Volume: 14

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combi

2014
Does pathologic response of rectal cancer influence postoperative morbidity after neoadjuvant radiochemotherapy and total mesorectal excision?
    Surgery, 2014, Volume: 155, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2014
Laparoscopic abdominosacral resection for locally advanced primary rectal cancer after treatment with mFOLFOX6 plus bevacizumab, followed by preoperative chemoradiotherapy.
    Asian journal of endoscopic surgery, 2014, Volume: 7, Issue:1

    Topics: Abdomen; Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplas

2014
A clinical study of metastasized rectal cancer treatment: assessing a multimodal approach.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2014
Local recurrence after complete clinical response and watch and wait in rectal cancer after neoadjuvant chemoradiation: impact of salvage therapy on local disease control.
    International journal of radiation oncology, biology, physics, 2014, Mar-15, Volume: 88, Issue:4

    Topics: Algorithms; Antineoplastic Agents; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Fluor

2014
Local recurrence after complete clinical response and watch and wait in rectal cancer after neoadjuvant chemoradiation: impact of salvage therapy on local disease control.
    International journal of radiation oncology, biology, physics, 2014, Mar-15, Volume: 88, Issue:4

    Topics: Algorithms; Antineoplastic Agents; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Fluor

2014
Local recurrence after complete clinical response and watch and wait in rectal cancer after neoadjuvant chemoradiation: impact of salvage therapy on local disease control.
    International journal of radiation oncology, biology, physics, 2014, Mar-15, Volume: 88, Issue:4

    Topics: Algorithms; Antineoplastic Agents; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Fluor

2014
Local recurrence after complete clinical response and watch and wait in rectal cancer after neoadjuvant chemoradiation: impact of salvage therapy on local disease control.
    International journal of radiation oncology, biology, physics, 2014, Mar-15, Volume: 88, Issue:4

    Topics: Algorithms; Antineoplastic Agents; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Fluor

2014
MRI and FDG-PET for assessment of response to neoadjuvant chemotherapy in locally advanced rectal cancer.
    Annals of surgical oncology, 2014, Volume: 21, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Capecitabine; Chemoth

2014
Over compliance with capecitabine oral chemotherapy.
    International journal of clinical pharmacy, 2014, Volume: 36, Issue:2

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Hu

2014
Cetuximab-induced esophageal ulcer: the first report in literature.
    The Libyan journal of medicine, 2014, Volume: 9, Issue:1

    Topics: Abdomen, Acute; Adenocarcinoma; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2014
Neoadjuvant capecitabine and oxaliplatin (XELOX) combined with bevacizumab for high-risk localized rectal cancer.
    Cancer chemotherapy and pharmacology, 2014, Volume: 73, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Comb

2014
[Concomitant use of romiplostim and chemotherapy for advanced rectal cancer associated with idiopathic thrombocytopenic purpura].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2014, Volume: 111, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Capecitabine; Deoxycytidine; Female; Fluorou

2014
Preoperative chemoradiotherapy in rectal cancer induces changes in the expression of nuclear β-catenin: prognostic significance.
    BMC cancer, 2014, Mar-15, Volume: 14

    Topics: Antimetabolites, Antineoplastic; beta Catenin; Cadherins; Capecitabine; Chemoradiotherapy; Colorecta

2014
A complete response to mFOLFOX6 and panitumumab chemotherapy in advanced stage rectal adenocarcinoma: a case report.
    World journal of surgical oncology, 2014, Mar-26, Volume: 12

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil

2014
[Feasibility study on Xelox (capecitabine plus oxapliplatin) in the volumetric modulated arc therapy (VMAT)-based preoperative chemoradiotherapy for locally advanced rectal cancer].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2014, Volume: 17, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Feas

2014
Primary squamous cell carcinoma of the most distal rectum: a dilemma in origin and management.
    BMJ case reports, 2014, Apr-02, Volume: 2014

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemoradioth

2014
P21 and CD166 as predictive markers of poor response and outcome after fluorouracil-based chemoradiotherapy for the patients with rectal cancer.
    BMC cancer, 2014, Apr-04, Volume: 14

    Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Biomarkers, Tumor; Cell Adhesion Molecules, Neuronal;

2014
Gastrointestinal: bevacizumab-induced reversible posterior leukoencephalopathy syndrome in patient with rectal cancer.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:5

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab

2014
The effects of neoadjuvant chemoradiotherapy on physical fitness and morbidity in rectal cancer surgery patients.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2014, Volume: 40, Issue:11

    Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Cohort Studies; De

2014
The role of tissue diagnosis prior to neoadjuvant chemoradiotherapy for locally advanced rectal cancer.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2014, Volume: 16, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Chemoradiot

2014
Late complications after proctectomy in rectal cancer patients who underwent radiotherapy.
    World journal of surgery, 2014, Volume: 38, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antineoplastic Agents; Case-C

2014
Can a biomarker-based scoring system predict pathologic complete response after preoperative chemoradiotherapy for rectal cancer?
    Diseases of the colon and rectum, 2014, Volume: 57, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Biomarkers, Tumor; Biopsy; Chemoradiotherapy; Combined Modality Therapy

2014
Neoadjuvant chemoradiation with concomitant boost radiotherapy associated to capecitabine in rectal cancer patients.
    International journal of colorectal disease, 2014, Volume: 29, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Capecit

2014
Interval between neoadjuvant treatment and definitive surgery in locally advanced rectal cancer: impact on response and oncologic outcomes.
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Digestive

2014
[A case of advanced rectal cancer that showed complete response to the addition of XELOX+bevacizumab therapy to preoperative chemoradiotherapy with S-1/CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camp

2014
[The combination of neoadjuvant chemoradiotherapy and epidermal growth factor receptor inhibitors in the treatment of rectal adenocarcinoma].
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2014, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adj

2014
Effect of long interval between hyperthermochemoradiation therapy and surgery for rectal cancer on apoptosis, proliferation and tumor response.
    Anticancer research, 2014, Volume: 34, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Prolife

2014
Prognostic factors for postoperative morbidity and tumour response after neoadjuvant chemoradiation followed by resection for rectal cancer.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2014, Volume: 18, Issue:9

    Topics: Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Anastomotic Leak; Antimetabolites, Anti

2014
Helical tomotherapy combined with capecitabine in the preoperative treatment of locally advanced rectal cancer.
    BioMed research international, 2014, Volume: 2014

    Topics: Adult; Aged; Aged, 80 and over; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluo

2014
Post-chemoradiation intraoperative electron-beam radiation therapy boost in resected locally advanced rectal cancer: long-term results focused on topographic pattern of locoregional relapse.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 112, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; E

2014
Risk factors for bowel dysfunction after sphincter-preserving rectal cancer surgery: a prospective study using the Memorial Sloan Kettering Cancer Center bowel function instrument.
    Diseases of the colon and rectum, 2014, Volume: 57, Issue:8

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab

2014
Fat composition changes in bone marrow during chemotherapy and radiation therapy.
    International journal of radiation oncology, biology, physics, 2014, Sep-01, Volume: 90, Issue:1

    Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Co

2014
Tumour regression grading after chemoradiotherapy for locally advanced rectal cancer: a near pathologic complete response does not translate into good clinical outcome.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 112, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineopl

2014
EGFR ligands and DNA repair genes: genomic predictors of complete response after capecitabine-based chemoradiotherapy in locally advanced rectal cancer.
    The pharmacogenomics journal, 2015, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Co

2015
Adjuvant treatment for locally advanced rectal cancer patients after preoperative chemoradiotherapy: when, and for whom?
    Clinical colorectal cancer, 2014, Volume: 13, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Comb

2014
Multidrug resistance-associated protein 3 confers resistance to chemoradiotherapy for rectal cancer by regulating reactive oxygen species and caspase-3-dependent apoptotic pathway.
    Cancer letters, 2014, Oct-28, Volume: 353, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Apoptosis; Caspase 3; Cell

2014
Overexpression of CPS1 is an independent negative prognosticator in rectal cancers receiving concurrent chemoradiotherapy.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:11

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Carbamoyl-Phosphate Syntha

2014
S-1-Based versus capecitabine-based preoperative chemoradiotherapy in the treatment of locally advanced rectal cancer: a matched-pair analysis.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Capecitabine; Chemoradiotherapy; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Humans; Mal

2014
Impact of perineural and lymphovascular invasion on oncological outcomes in rectal cancer treated with neoadjuvant chemoradiotherapy and surgery.
    Annals of surgical oncology, 2015, Volume: 22, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemoradiotherapy

2015
Adjuvant chemotherapy for patients with rectal cancer?
    The Lancet. Oncology, 2014, Volume: 15, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Fluorouracil; Humans; Leu

2014
Transanal endoscopic microsurgery with entrance into the peritoneal cavity: is it safe?
    Diseases of the colon and rectum, 2014, Volume: 57, Issue:10

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Blood Loss, Su

2014
Adaptation of international guidelines for metastatic colorectal cancer: an asian consensus.
    Clinical colorectal cancer, 2014, Volume: 13, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2014
Intussusception due to rectal adenocarcinoma in a young adult: a case report.
    World journal of gastroenterology, 2014, Sep-21, Volume: 20, Issue:35

    Topics: Abdominal Pain; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; B

2014
Clinical and dosimetric predictors of acute hematologic toxicity in rectal cancer patients undergoing chemoradiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 113, Issue:1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemoth

2014
Role of genetic polymorphisms in NFKB-mediated inflammatory pathways in response to primary chemoradiation therapy for rectal cancer.
    International journal of radiation oncology, biology, physics, 2014, Nov-01, Volume: 90, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Capecitabine; Chemoradiotherapy; Cyclooxygenase 1; Cyclooxygenase 2;

2014
IQGAP1 in rectal adenocarcinomas: localization and protein expression before and after radiochemotherapy.
    Cancer letters, 2015, Jan-28, Volume: 356, Issue:2 Pt B

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor;

2015
[Influence of preoperative chemoradiotherapy on changes of epidermal growth factor receptor expression in patients treated by preoperative chemoradiotherapy for local advanced rectal carcinoma].
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2014, Volume: 27, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuv

2014
Neoadjuvant bevacizumab and chemoradiotherapy in locally advanced rectal cancer: early outcome and technical impact on toxicity.
    World journal of surgical oncology, 2014, Nov-06, Volume: 12

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2014
Complete Neoadjuvant Treatment for Rectal Cancer: The Brown University Oncology Group CONTRE Study.
    American journal of clinical oncology, 2017, Volume: 40, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherap

2017
Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation.
    World journal of gastroenterology, 2014, Nov-14, Volume: 20, Issue:42

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Chemoradiot

2014
[A case of mFOLFOX6-induced lactic acidosis in a patient with colon cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:11

    Topics: Acidosis, Lactic; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin;

2014
Association between the cytogenetic profile of tumor cells and response to preoperative radiochemotherapy in locally advanced rectal cancer.
    Medicine, 2014, Volume: 93, Issue:26

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Ad

2014
Comparative survival effectiveness between pre-operative and postoperative chemoradiotherapy for locally advanced rectal cancer: a retrospective study in Phramongkutklao Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014, Volume: 97 Suppl 2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy; Combined Modalit

2014
Pathological response of locally advanced rectal cancer to preoperative chemotherapy without pelvic irradiation.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2015, Volume: 17, Issue:6

    Topics: Adult; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemor

2015
[Combined treatment of patients with locally advanced rectal cancer].
    Voprosy onkologii, 2014, Volume: 60, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2014
Relationships between SMAD3 expression and preoperative fluoropyrimidine-based chemoradiotherapy response in locally advanced rectal cancer patients.
    World journal of surgery, 2015, Volume: 39, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Disease-Free Surv

2015
Efficacy and safety of neoadjuvant intensity-modulated radiotherapy with concurrent capecitabine for locally advanced rectal cancer.
    Diseases of the colon and rectum, 2015, Volume: 58, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemo

2015
Downstage migration after neoadjuvant chemoradiotherapy for rectal cancer: the reverse of the Will Rogers phenomenon?
    Cancer, 2015, Jun-01, Volume: 121, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Clinical Trials, Phase

2015
Adjuvant chemoradiation plus intraoperative radiotherapy versus adjuvant chemoradiation alone in patients with locally advanced rectal cancer.
    American journal of clinical oncology, 2015, Volume: 38, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju

2015
Observational study of adjuvant therapy with capecitabine in colon cancer.
    Current medical research and opinion, 2015, Volume: 31, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; C

2015
Elevated platelet count as predictor of recurrence in rectal cancer patients undergoing preoperative chemoradiotherapy followed by surgery.
    International surgery, 2015, Volume: 100, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers; Female; Fluorouracil; F

2015
[Efficiency of pre-operative chemoradiotherapy in treating a case of advanced rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy;

2014
[Surgical resection after chemotherapy for advanced rectal cancer - report of a case].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protoc

2014
[A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Hum

2014
[Irradiation with carbon ions for locally recurrent rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Heavy Io

2014
[A case of neoadjuvant chemotherapy for locally advanced rectal cancer, which had a invasion into the vagina followed by curative resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Laparoscopy; Leucovori

2014
[A case of stage IV rectal cancer successfully resected after chemotherapy (mFOLFOX6 plus panitumumab)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Ther

2014
[A case of rectal cancer with brain metastasis successfully treated with combined modality therapy - a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2014
[A case of metastatic rectal cancer with fulminant hepatitis caused by XELOX therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Hep

2014
Safety and efficacy of adjuvant therapy with oxaliplatin, leucovorin and 5-fluorouracil after mesorectal excision with lateral pelvic lymph node dissection for stage iii lower rectal cancer.
    Anticancer research, 2015, Volume: 35, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluo

2015
[Preoperative chemoradiotherapy for rectal cancer: experience from one centre].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2015, Volume: 19, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Pro

2015
Sustaining Blood Lymphocyte Count during Preoperative Chemoradiotherapy as a Predictive Marker for Pathologic Complete Response in Locally Advanced Rectal Cancer.
    Cancer research and treatment, 2016, Volume: 48, Issue:1

    Topics: Adult; Aged; Biomarkers, Pharmacological; Chemoradiotherapy; Female; Fluorouracil; Humans; Lymphocyt

2016
Potential Role of Single Nucleotide Polymorphisms of XRCC1, XRCC3, and RAD51 in Predicting Acute Toxicity in Rectal Cancer Patients Treated With Preoperative Radiochemotherapy.
    American journal of clinical oncology, 2017, Volume: 40, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiothera

2017
[The present status of CapeOX as adjuvant chemotherapy for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy,

2015
Inferior mesenteric artery chemoembolization and chemotherapy for advanced rectal cancer: report of a clinical case.
    Tumori, 2015, Jun-25, Volume: 101, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Female

2015
Adjuvant Chemotherapy for Locally Advanced Rectal Cancer: Is It a Given?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jun-10, Volume: 33, Issue:17

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2015
Comprehensive evaluation of the effectiveness of gene expression signatures to predict complete response to neoadjuvant chemoradiotherapy and guide surgical intervention in rectal cancer.
    Cancer genetics, 2015, Volume: 208, Issue:6

    Topics: Adenocarcinoma; Chemoradiotherapy; Female; Fluorouracil; Gene Expression Profiling; Gene Expression

2015
[Predictive value of preoperative imaging and postoperative pathology on clinical complete response after neoadjuvant chemoradiation for locally advanced rectal cancer].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2015, Volume: 18, Issue:5

    Topics: Chemoradiotherapy; Fluorouracil; Humans; Magnetic Resonance Imaging; Neoadjuvant Therapy; Neoplasm S

2015
Evaluating Variations of Bladder Volume Using an Ultrasound Scanner in Rectal Cancer Patients during Chemoradiation: Is Protocol-Based Full Bladder Maintenance Using a Bladder Scanner Useful to Maintain the Bladder Volume?
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Female; Fluorouracil; Gamma Rays; Humans; Leucovorin; Logistic M

2015
Correlation of CEA but not CA 19-9 as serum biomarkers of disease activity in a case of metastatic rectal adenocarcinoma.
    Cancer biology & therapy, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; CA-19-9 Antigen;

2015
Role of Adjuvant Chemotherapy in ypT0-2N0 Patients Treated with Preoperative Chemoradiation Therapy and Radical Resection for Rectal Cancer.
    International journal of radiation oncology, biology, physics, 2015, Jul-01, Volume: 92, Issue:3

    Topics: Adenocarcinoma; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chem

2015
High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer.
    Radiation oncology (London, England), 2015, Jun-13, Volume: 10

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Baculoviral

2015
Comparison of oncologic outcomes of metastatic rectal cancer patients with or without neoadjuvant chemoradiotherapy.
    International journal of colorectal disease, 2015, Volume: 30, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitab

2015
The outcome of 5-fluorouracil chemotherapy after the completion of neoadjuvant chemoradiotherapy, administered until 2 weeks before rectal cancer resection.
    Journal of the Chinese Medical Association : JCMA, 2015, Volume: 78, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy; Female; Fluorour

2015
Neoadjuvant therapy does not affect lymph node ratio in rectal cancer.
    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 2016, Volume: 14, Issue:5

    Topics: Adenocarcinoma; Aged; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil; Humans; I

2016
[A Case of Concurrent Cancer in a Giant Rectal Villous Adenoma That Resulted in Extensive Lymph Node Metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:6

    Topics: Adenoma, Villous; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy,

2015
The outcome and the frequency of pathological complete response after neoadjuvant radiotherapy in curative resections for advanced rectal cancer: a population-based study.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2016, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemoradiotherapy; Cohort Studies; Digestive

2016
Clinical outcomes of elderly patients receiving neoadjuvant chemoradiation for locally advanced rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape

2015
Chemoradiation for High-grade Neuroendocrine Carcinoma of the Rectum and Anal Canal.
    American journal of clinical oncology, 2017, Volume: 40, Issue:6

    Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Camptotheci

2017
Prediction of neoadjuvant radiation chemotherapy response and survival using pretreatment [(18)F]FDG PET/CT scans in locally advanced rectal cancer.
    European journal of nuclear medicine and molecular imaging, 2016, Volume: 43, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Disease-Free

2016
[Using "Collegel" complex in combined therapy of rectum cancer].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2015, Issue:4

    Topics: Administration, Rectal; Alginates; Antineoplastic Combined Chemotherapy Protocols; Combined Modality

2015
[A Case of Radical Resection of Rectal Cancer with Multiple Liver and Lung Metastases after Preoperative Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:10

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; F

2015
Further evidence for preoperative chemoradiotherapy and transanal endoscopic surgery (TEM) in T2-3s,N0,M0 rectal cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2016, Volume: 18, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Che

2016
Long Term Outcomes of Preoperative versus Postoperative Concurrent Chemoradiation for Locally Advanced Rectal Cancer: Experience from Ramathibodi Medical School in Thailand.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:16

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fem

2015
[Long-Term Successful Management of Recurrent Rectal Cancer in the Predialysis State with FOLFIRI Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dialysis; Fatal Outcome; Fluorou

2015
Therapy-Induced Cellular Senescence Induces Epithelial-to-Mesenchymal Transition and Increases Invasiveness in Rectal Cancer.
    Clinical colorectal cancer, 2016, Volume: 15, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cellular Senescence; Doxorubicin; Epithelial-

2016
Watch-and-wait approach versus surgical resection after chemoradiotherapy for patients with rectal cancer (the OnCoRe project): a propensity-score matched cohort analysis.
    The Lancet. Oncology, 2016, Volume: 17, Issue:2

    Topics: Adenocarcinoma; Aged; Case-Control Studies; Chemoradiotherapy, Adjuvant; Colostomy; Disease-Free Sur

2016
Pilot Study of Neoadjuvant Chemoradiotherapy with Three Cycles of 5-Fluorouracil Plus Leucovorin for Treatment of Locally Advanced Rectal Cancer.
    Annals of surgical oncology, 2016, Volume: 23, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Case

2016
Capecitabine-Induced Severe Toxicity Secondary to DPD Deficiency and Successful Treatment with Low Dose 5-Fluorouracil.
    Journal of gastrointestinal cancer, 2017, Volume: 48, Issue:1

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Dihydropyrimidine Dehydrogenase Deficiency; Dose-Resp

2017
[A Patient with Rectal Cancer and Multiple Lung Metastases Treated with XELOX plus Bevacizumab (Bev) Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colectomy; Deoxycyt

2015
[Two Cases of Curative Resection of Locally Advanced Rectal Cancer after Preoperative Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Male; Methot

2015
[A Patient with Recurrent Ulcerative Colitis-Associated Rectal Cancer Attaining a Complete Response with FOLFIRI plus Bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colitis, Ulcerative; Comb

2015
[Recurrence of Rectal Cancer with Submucosal Invasion in the Bone and Lymph Nodes 89 Months after Surgery--A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone Neoplasms; Camptot

2015
[Conversion Therapy of Initially Unresectable Rectal Cancer with Perforation via FOLFOX4 Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colostomy; Combined

2015
[A Case of Rectal Cancer with Multiple Liver, Lung, and Para-Aortic Lymph Node Metastases Successfully Treated with FOLFOX4 plus Bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aorta; Bevacizumab; Chemotherapy, Adjuvant; Fl

2015
[A Case of Thrombotic Thrombocytopenic Purpura in a Patient Undergoing FOLFOX6 plus Panitumumab Therapy for Unresectable Recurrent Rectal Cancer with a Rapidly Progressive Course].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:1

    Topics: ADAM Proteins; ADAMTS13 Protein; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy

2016
Evaluation of Preoperative Chemotherapy with Modified OPTIMOX-1 Plus Bevacizumab in Patients with Advanced Rectal Cancer with Factors Contraindicative of Curative Surgery.
    Hepato-gastroenterology, 2015, Volume: 62, Issue:140

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cohort Stu

2015
Impact of age on efficacy of postoperative oxaliplatin-based chemotherapy in patients with rectal cancer after neoadjuvant chemoradiotherapy.
    Oncotarget, 2016, Apr-12, Volume: 7, Issue:15

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Fluoro

2016
Comparative effectiveness of postoperative chemotherapy among older patients with non-metastatic rectal cancer treated with preoperative chemoradiotherapy.
    Journal of geriatric oncology, 2016, Volume: 7, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothe

2016
NF-κB/p65 expression before and after treatment in rectal cancer patients undergoing neoadjuvant (chemo)radiotherapy and surgery: prognostic marker for disease progression and survival.
    Neoplasma, 2016, Volume: 63, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; C

2016
Sequential boost in neoadjuvant irradiation for T3N0-1 rectal cancer: long-term results from a single-center experience.
    Tumori, 2016, Jun-02, Volume: 2016, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Dig

2016
Long-Term Bone Marrow Suppression During Postoperative Chemotherapy in Rectal Cancer Patients After Preoperative Chemoradiation Therapy.
    International journal of radiation oncology, biology, physics, 2016, Apr-01, Volume: 94, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Dise

2016
[Individual Dose Adjustment of 5-Fluorouracil Based on Pharmacokinetic Monitoring May Improve the Outcome of FOLFOX for Metastatic Colorectal Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female;

2016
[Adjuvant Systemic Chemotherapy with S-1/Oxaliplatin or mFOLFOX6 after Curative Resection of Distant Metastases in Patients with Colorectal Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Dru

2016
[A Case of an Unresectable Locally Advanced Rectal Cancer with Surrounding Organ Invasion Successfully Resected after Chemotherapy with mFOLFOX6 plus Cetuximab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Fluorouracil; Humans; Leucovorin; Male; M

2016
[Analysis of risk factors of distant metastasis in rectal cancer patients who received total mesorectal excision following neoadjuvant chemoradiotherapy].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2016, Volume: 19, Issue:4

    Topics: Chemoradiotherapy; Digestive System Surgical Procedures; Fluorouracil; Humans; Neoadjuvant Therapy;

2016
[Analysis of clinical predictive factors of pathologic complete response after neoadjuvant chemoradiotherapy in rectal cancer].
    Zhonghua yi xue za zhi, 2016, Apr-26, Volume: 96, Issue:16

    Topics: Adenocarcinoma; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant Therapy; Radiotherapy, Intensit

2016
Intensity-Modulated Radiotherapy in Neoadjuvant Concurrent Chemoradiotherapy for Locally Advanced Rectal Cancer.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:6

    Topics: Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant Therapy; Radiotherapy, Intensity-Modulated; Rec

2016
Oncologic Safety of Local Excision Compared With Total Mesorectal Excision for ypT0-T1 Rectal Cancer: A Propensity Score Analysis.
    Medicine, 2016, Volume: 95, Issue:20

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape

2016
[A Case of Unresectable Rectal Cancer with Multiple Liver Metastases Treated Effectively with 22 Courses of XELOX Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Humans; L

2016
[A Case of Advanced Rectal Cancer Resected Successfully after Induction Chemotherapy with Modified FOLFOX6 plus Panitumumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:5

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil

2016
Non-surgical management of rectal cancer. Series of 68 cases, long follow up in two leading centres in Argentina.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2016, Volume: 48, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Argentina; Chemoradiotherapy; Disease-F

2016
[Research hotspot and progress of preoperative chemoradiotherapy for rectal cancer].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2016, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Chemoradiotherapy; Deoxyc

2016
[Clinical study on locally advanced rectal cancer patients with pathological complete response after neoadjuvant chemoradiotherapy].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2016, Volume: 19, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothe

2016
[Expression of CD133 in rectal cancer tissues and its relationship with neoadjuvant chemoradiotherapy].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2016, Volume: 19, Issue:6

    Topics: AC133 Antigen; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deox

2016
Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
    Journal of translational medicine, 2016, 07-01, Volume: 14, Issue:1

    Topics: Biomarkers, Tumor; Calnexin; Cell Death; Cell Survival; Clone Cells; Colorectal Neoplasms; Endoplasm

2016
Genetic polymorphisms in 5-Fluorouracil-related enzymes predict pathologic response after neoadjuvant chemoradiation for rectal cancer.
    Surgery, 2016, Volume: 160, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Chemoradiotherapy; Databases, Factual; Female; Fluorouracil; Genotyp

2016
[A Case of Fournier's Gangrene Caused by Small Intestinal Perforation during Bevacizumab Combination Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Chemoradiotherapy; Drainage; Fatal Outc

2016
DNA Mismatch Repair Deficiency in Rectal Cancer: Benchmarking Its Impact on Prognosis, Neoadjuvant Response Prediction, and Clinical Cancer Genetics.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-01, Volume: 34, Issue:25

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Benchmarking; Biomarkers, Tumor; Chemoradioth

2016
[Short-term efficacy comparison between preoperative three dimensional conformal radiotherapy and volumetric modulated arc therapy concurrently combined with chemotherapy in the treatment of locally advanced rectal carcinoma].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2016, Volume: 19, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Fema

2016
PD-L1 is upregulated by radiochemotherapy in rectal adenocarcinoma patients and associated with a favourable prognosis.
    European journal of cancer (Oxford, England : 1990), 2016, Volume: 65

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; B7-H1 Antigen; Biomarkers, Tumor; Chemoradiother

2016
Outcomes of Preoperative Chemoradiotherapy and Combined Chemotherapy with Radiotherapy Without Surgery for Locally Advanced Rectal Cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2016, Volume: 17, Issue:7

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capeci

2016
[A Case of Liver Metastasis from Colorectal Cancer That Showed a Pathological Complete Response to mFOLFOX6 plus Cetuximab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Combined Modality Therapy; Fluorour

2016
Adjuvant chemoradiotherapy instead of revision radical resection after local excision for high-risk early rectal cancer.
    Radiation oncology (London, England), 2016, Sep-05, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, A

2016
Preoperative chemoradiotherapy for elderly patients with locally advanced rectal cancer-a real-world outcome study.
    Japanese journal of clinical oncology, 2016, Volume: 46, Issue:12

    Topics: Age Factors; Aged; Aged, 80 and over; Capecitabine; Chemoradiotherapy; Diarrhea; Disease-Free Surviv

2016
Management of rectal cancer: the 2016 French guidelines.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2017, Volume: 19, Issue:2

    Topics: Adenocarcinoma; Anal Canal; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Chemoradiotherap

2017
Adjuvant treatment for resected rectal cancer: impact of standard and intensified postoperative chemotherapy on disease-free survival in patients undergoing preoperative chemoradiation-a propensity score-matched analysis of an observational database.
    Langenbeck's archives of surgery, 2016, Volume: 401, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy, Adjuvant; Da

2016
Discriminating cancer-related and cancer-unrelated chemoradiation-response genes for locally advanced rectal cancers.
    Scientific reports, 2016, 11-15, Volume: 6

    Topics: Aged; Algorithms; DNA Repair; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans;

2016
A Retrospective Analysis on Two-week Short-course Pre-operative Radiotherapy in Elderly Patients with Resectable Locally Advanced Rectal Cancer.
    Scientific reports, 2016, 11-25, Volume: 6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy,

2016
Is routine use of adjuvant chemotherapy for rectal cancer with complete pathological response justified?
    American journal of surgery, 2017, Volume: 213, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-F

2017
Prognostic Value of Sterilized Lymph Nodes After Preoperative Chemoradiotherapy for Patients with ypN0 Rectal Cancer.
    Annals of surgical oncology, 2017, Volume: 24, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Disease-Free Surv

2017
Reply to I. Gounaris and M. Hall et al.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, 05-01, Volume: 35, Issue:13

    Topics: Fluorouracil; Humans; Leucovorin; Neoadjuvant Therapy; Prostatic Neoplasms; Rectal Neoplasms

2017
We Have the Tools: It's Time to Use Them Correctly!
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, 05-01, Volume: 35, Issue:13

    Topics: Fluorouracil; Humans; Leucovorin; Neoadjuvant Therapy; Rectal Neoplasms; Research Design

2017
Comment on the FOWARC Study Report.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, 05-01, Volume: 35, Issue:13

    Topics: Fluorouracil; Humans; Leucovorin; Neoadjuvant Therapy; Rectal Neoplasms; Rectum

2017
[Two Cases of Metastatic Rectal Cancer Patients Who Received Chemotherapy with FOLFOXIRI plus Bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Female; Fluorourac

2016
[A Patient with Colon Cancer Local Site Recurrence Who Experienced Difficulty Tolerating Intensive Chemotherapy Was Treated Effectively with sLV5FU2 Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Abdominal Neoplasms; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil

2016
[Pathological Complete Response in a Case of Multiple Liver Metastases from Rectal Cancer Treated with XELOX plus Bevacizumab(Bev)Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colectomy; Combined Modal

2016
[A Case of Rectal Cancer with Unresectable Liver Metastasis Responding to Rechallenge with FOLFIRI].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Fluorouracil;

2016
[A Case of Advanced Rectal Cancer Resulting in a Pathologically Complete Response after Neoadjuvant Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deo

2016
Prediction of Pathological Complete Response Using Endoscopic Findings and Outcomes of Patients Who Underwent Watchful Waiting After Chemoradiotherapy for Rectal Cancer.
    Diseases of the colon and rectum, 2017, Volume: 60, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc

2017
Patients with pathological stage N2 rectal cancer treated with early adjuvant chemotherapy have a lower treatment failure rate.
    BMC cancer, 2017, 03-09, Volume: 17, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuva

2017
Prinzmetal angina (Coronary vasospasm) associated with 5-fluorouracil chemotherapy.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:7

    Topics: Administration, Sublingual; Antineoplastic Combined Chemotherapy Protocols; Chest Pain; Coronary Ang

2017
FOLFOX and intensified split-course chemoradiation as initial treatment for rectal cancer with synchronous metastases.
    Acta oncologica (Stockholm, Sweden), 2017, Volume: 56, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; F

2017
Pneumatosis cystoides intestinalis after fluorouracil chemotherapy for rectal cancer.
    World journal of gastroenterology, 2008, May-28, Volume: 14, Issue:20

    Topics: Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2008
Combined cetuximab, capecitabine, oxaliplatin, and radiotherapy in rectal cancer: Dr. Jekyll or Mr. Hyde? In regard to Rödel et al. (Int J Radiat Oncol Biol Phys 2008;70:1081-1086.).
    International journal of radiation oncology, biology, physics, 2008, Jul-01, Volume: 71, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2008
Local excision of distal rectal cancer: an update of cancer and leukemia group B 8984.
    Diseases of the colon and rectum, 2008, Volume: 51, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality T

2008
Transanal endoscopic microsurgery for the treatment of selected patients with distal rectal cancer: 15 years experience.
    Surgical endoscopy, 2008, Volume: 22, Issue:9

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survi

2008
The prognostic value of lymph node metastases and tumour regression grade in rectal cancer patients treated with long-course preoperative chemoradiotherapy.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2009, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Age Factors; Aged; Chemotherapy, Adjuvant; Cohort Studies; Colectomy; Female; Fluoro

2009
Granulocyte-colony stimulating factor producing rectal cancer.
    World journal of surgical oncology, 2008, Jun-29, Volume: 6

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colectomy; Fatal Outcome;

2008
[Pathomorphosis of rectal cancer after irradiation on the background of intra-arterial regional chemotherapy].
    Klinichna khirurhiia, 2008, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Cancer, Regional Perfusion; Female; Fluorouraci

2008
Accuracy of endorectal ultrasonography in staging locally advanced rectal cancer after preoperative chemoradiation.
    Surgical endoscopy, 2008, Volume: 22, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Endosonography; Fem

2008
[Combination chemotherapy composed of mFOLFOX 6, FOLFIRI 2 and surgery and radiation therapy for locoregional recurrences and multiple lung metastases from rectal cancer--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoembryonic Antigen; Cisplatin; C

2008
[5-FU/LV therapy for a rectal cancer patient undergoing continuous hemodialysis with multiple hepatic metastases--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:7

    Topics: Biomarkers, Tumor; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Middle Aged; Rectal Neop

2008
[Rectal adenocarcinoma metastasis to the facial skin--case report].
    Otolaryngologia polska = The Polish otolaryngology, 2008, Volume: 62, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Facial Neopl

2008
Desensitization to oxaliplatin with two stages of premedication in a patient with metastatic rectal cancer.
    Clinical therapeutics, 2008, Volume: 30, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Desensitization, Immunologic;

2008
Biological image-guided radiotherapy in rectal cancer: is there a role for FMISO or FLT, next to FDG?
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:7

    Topics: Antimetabolites, Antineoplastic; Cell Hypoxia; Combined Modality Therapy; Dideoxynucleosides; Fluoro

2008
Micro-RNAs miR125b and miR137 are frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer.
    International journal of oncology, 2008, Volume: 33, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine

2008
Early clinical results from chemoradiation with 5-fluorouracil and oxaliplatin for locally advanced rectal cancer.
    Clinical colorectal cancer, 2008, Volume: 7, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemotherapy, Adjuvant; Cohor

2008
A simplified tumor regression grade correlates with survival in locally advanced rectal carcinoma treated with neoadjuvant chemoradiotherapy.
    Annals of surgical oncology, 2008, Volume: 15, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv

2008
[A case with liver resection of metastasis from rectal cancer after FOLFOX4+bevacizumab treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:10

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2008
[A case of increased resectability with preoperative chemotherapy FOLFOX4 for unresectable rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonoscopy; Fluorouracil;

2008
Hepatic arterial infusion chemotherapy combined with venous embolization in a patient with hepatic metastases with an arteriovenous shunt.
    Cardiovascular and interventional radiology, 2009, Volume: 32, Issue:4

    Topics: Angiography; Antimetabolites, Antineoplastic; Arteriovenous Fistula; Combined Modality Therapy; Cont

2009
Use of molecular imaging to predict clinical outcome in patients with rectal cancer after preoperative chemotherapy and radiation.
    International journal of radiation oncology, biology, physics, 2009, May-01, Volume: 74, Issue:1

    Topics: Adenocarcinoma; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Capecitabine;

2009
[A case of diffusely infiltrating rectal cancer with pulmonary lymphangitis carcinomatosa successfully treated with mFOLFOX6 chemotherapy as salvage].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Fluorouracil; Humans

2008
[A case of metastatic lung and liver tumors from rectal cancer treated with oral UFT and CPT-11 by hepatic arterial infusion followed by FOLFOX and FOLFIRI].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:11

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptotheci

2008
[Epiphora in a patient receiving FOLFOX therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Lacrimal Apparatus Disea

2008
Can an FDG-PET/CT predict tumor clearance of the mesorectal fascia after preoperative chemoradiation of locally advanced rectal cancer?
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2008, Volume: 184, Issue:9

    Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fasci

2008
Regression of rectal cancer with radiotherapy with or without concurrent capecitabine--optimising the timing of surgical resection.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2009, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Female

2009
Relationships of insulin-like growth factor-1 receptor and epidermal growth factor receptor expression to clinical outcomes in patients with colorectal cancer.
    Oncology, 2009, Volume: 76, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Colorectal Neoplasm

2009
Neo-adjuvant chemoradiotherapy in advanced rectal carcinoma: a note of caution.
    Irish medical journal, 2008, Volume: 101, Issue:9

    Topics: Adenocarcinoma; Fatal Outcome; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Rectal

2008
Alterations in hormone levels after adjuvant chemoradiation in male rectal cancer patients.
    International journal of radiation oncology, biology, physics, 2009, Jul-15, Volume: 74, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Fluorouracil; Follicle Stimula

2009
Epidermal growth factor receptor gene copy number, K-ras mutation and pathological response to preoperative cetuximab, 5-FU and radiation therapy in locally advanced rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2009
[Our experiences of preoperative chemo-radiotherapy for T4 primary rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Antineoplastic Agents; Drug Combinations; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Thera

2008
[A case of huge advanced rectal cancer invaded into the surrounding organs resected successfully after preoperative chemotherapy with mFOLFOX6].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Male; Neoadj

2008
[Modified FOLFOX6 treatment for obstructive jaundice caused by hepatic lymph-node metastasis from liver metastases of rectal cancer--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Female; Fluorouracil; Huma

2008
[A case report of a patient with hand-foot syndrome induced by bolus 5-fluorouracil therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Antineoplastic Agents; Chemistry, Pharmaceutical; Fluorouracil; Foot; Hand; Humans; Male; Middle Age

2008
[A case report of complete remission of relapsed rectal cancer liver metastasis after systemic chemotherapy successfully treated by radiofrequency ablation].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Catheter Ablation; Fluorouracil; Humans; Leucovorin;

2008
[Complete response of advanced rectal cancer with combined therapy of S-1 + chemo-radiation plus FOLFIRI--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Drug Combinations;

2008
[Hepatic artery infusion chemotherapy to three liver metastasis cases in which systemic chemotherapy was impossible or ineffective].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoembryonic Antigen; Female; Fluorouracil; Hepa

2008
Laparoscopic resection of extraperitoneal rectal cancer: a comparative analysis with open resection.
    Surgical endoscopy, 2009, Volume: 23, Issue:8

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Mod

2009
Caveolin-1 as a prognostic marker for local control after preoperative chemoradiation therapy in rectal cancer.
    International journal of radiation oncology, biology, physics, 2009, Mar-01, Volume: 73, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Caveolin 1; Deoxycytidine

2009
Risk of hypogonadism from scatter radiation during pelvic radiation in male patients with rectal cancer.
    International journal of radiation oncology, biology, physics, 2009, Aug-01, Volume: 74, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Brachytherapy; Fluorouracil; Follic

2009
[Pharmacokinetic monitoring of 5-fluorouracil may improve the clinical benefit with an individualized regimen-a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Monitoring; Fluorouracil; Humans; Liver N

2009
[A CR case of colorectal cancer given 39 courses of FOLFOX].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Combined Modality Therapy;

2009
To widen the setting of cancer patients who could benefit from metronomic capecitabine.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:1

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxyc

2009
Complete peritonectomy and intraperitoneal chemotherapy for recurrent rectal cancer with peritoneal metastasis.
    World journal of gastroenterology, 2009, Feb-14, Volume: 15, Issue:6

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2009
[Two cases of interstitial lung diseases in patients treated with oxaliplatin, 5-fluorouracil and Leucovorin (FOLFOX)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; L

2009
[Report of a case effectively treated by appropriate therapy for severe anticipatory nausea and vomiting due to FOLFOX or FOLFIRI].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Fluorouracil; Humans; Leucovorin; Male

2009
Fertility preservation for young women with rectal cancer--a combined approach from one referral center.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2009, Volume: 13, Issue:6

    Topics: Adult; Antimetabolites, Antineoplastic; Cryopreservation; Female; Fluorouracil; Humans; Infertility,

2009
Biological image-guided radiotherapy in rectal cancer: challenges and pitfalls.
    International journal of radiation oncology, biology, physics, 2009, Nov-01, Volume: 75, Issue:3

    Topics: Aged; Aged, 80 and over; Algorithms; Antimetabolites, Antineoplastic; Combined Modality Therapy; Fea

2009
A case of Takotsubo cardiomyopathy during 5-fluorouracil treatment for rectal adenocarcinoma.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2009, Volume: 76, Issue:1

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Female; Fluorouracil; Heart Failure; Humans; Middle

2009
Synchronous isolated adrenal metastasis from rectum adenocarcinoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2009, Volume: 11, Issue:4

    Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Female; Flu

2009
[A case of locally advanced rectal cancer responding to FOLFOX].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Magnetic Resonance

2009
[A successfully resected case of rectal cancer with liver metastases treated with mFOLFOX6 and bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2009
[A case report of complete response to RPMI regimen for multiple lymph node metastases following rectal cancer surgery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:4

    Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Fluorouracil; Humans; Leucovorin; Lymphatic Metastas

2009
Accuracy of MRI for predicting the circumferential resection margin, mesorectal fascia invasion, and tumor response to neoadjuvant chemoradiotherapy for locally advanced rectal cancer.
    Journal of magnetic resonance imaging : JMRI, 2009, Volume: 29, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Fascia; Female; Fluorouracil;

2009
Lymph node harvest after proctectomy for invasive rectal adenocarcinoma following neoadjuvant therapy: does the same standard apply?
    Diseases of the colon and rectum, 2009, Volume: 52, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2009
The role of dual-time combined 18-fluorodeoxyglucose positron emission tomography and computed tomography in the staging and restaging workup of locally advanced rectal cancer, treated with preoperative chemoradiation therapy and radical surgery.
    International journal of radiation oncology, biology, physics, 2009, Aug-01, Volume: 74, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorodeoxyglucose F18; Flu

2009
Suppression of the postoperative neutrophil leucocytosis following neoadjuvant chemoradiotherapy for rectal cancer and implications for surgical morbidity.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2010, Volume: 12, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Fl

2010
A case report of pathologically complete response of a huge rectal cancer after systemic chemotherapy with mFOLFOX6.
    Japanese journal of clinical oncology, 2009, Volume: 39, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; DNA-Binding Proteins; Dru

2009
Complete pathologic response after preoperative rectal cancer chemoradiotherapy.
    ANZ journal of surgery, 2009, Volume: 79, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Fr

2009
Postoperative chemotherapy after neoadjuvant chemoradiation and surgery for rectal cancer: is it essential for patients with ypT0-2N0?
    Journal of surgical oncology, 2009, Oct-01, Volume: 100, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv

2009
[A case of advanced gastric and rectal cancer (double cancer) successfully treated with mFOLFOX6 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:7

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P

2009
Intestinal permeability, vitamin A absorption, alpha-tocopherol, and neopterin in patients with rectal carcinoma treated with chemoradiation.
    Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Aged; alpha-Tocopherol; Antimetabolites, Antineoplastic; Antioxidants; Carbohydrates

2010
A case of 5-fluorouracil-induced acute psychosis.
    Clinical colorectal cancer, 2009, Volume: 8, Issue:3

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Comb

2009
Postoperative morbidity with diversion after low anterior resection in the era of neoadjuvant therapy: a single institution experience.
    Journal of the American College of Surgeons, 2009, Volume: 209, Issue:1

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antimetabolites,

2009
Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy.
    Annals of surgical oncology, 2009, Volume: 16, Issue:12

    Topics: AC133 Antigen; Adult; Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers

2009
Predicting grade 3 acute diarrhea during radiation therapy for rectal cancer using a cutoff-dose logistic regression normal tissue complication probability model.
    International journal of radiation oncology, biology, physics, 2010, May-01, Volume: 77, Issue:1

    Topics: Antimetabolites, Antineoplastic; Diarrhea; Dose-Response Relationship, Radiation; Fluorouracil; Huma

2010
Rectal angiosarcoma after adjuvant chemoradiotherapy for adenocarcinoma of the rectum.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-20, Volume: 27, Issue:27

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Fatal Outcome; Fluorouracil

2009
[The pharmacokinetics and safety of oxaliplatin in a hemodialysis patient treated with mFOLFOX6 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:8

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P

2009
Hyperfractionated accelerated radiotherapy for rectal cancer in patients with prior pelvic irradiation.
    International journal of radiation oncology, biology, physics, 2010, May-01, Volume: 77, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deox

2010
Predictive factors of pathologic complete response after neoadjuvant chemoradiation for rectal cancer.
    Annals of surgery, 2009, Volume: 250, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chi-Square Distribution; Female; Fl

2009
Microdissection is essential for gene expression analysis of irradiated rectal cancer tissues.
    Oncology reports, 2009, Volume: 22, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dih

2009
[Prognostic analysis of 443 cases of stage II colorectal cancer and the value of adjuvant chemotherapy].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecita

2009
[Multivariate analysis of clinicopathologic factors correlated with pathological complete response following preoperative radiotherapy in rectal adenocarcinoma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Carcinoembryonic An

2009
[Risk factors related to lymph node metastases after neoadjuvant therapy for locally advanced rectal cancer].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; CA-1

2009
[Correlation of chemosensitivity tested using histoculture drug response assay to expression of multidrug resistance genes and proteins in colorectal cancer tissues].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Tr

2009
[Clinical significance of a transient increase in carcinoembryonic antigen and carbohydrate antigen 19-9 in patients with metastatic colorectal cancer receiving chemotherapy].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:9

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Ant

2009
[A case of rectal cancer with liver metastases successfully treated with modified FOLFOX6 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; He

2009
[Practical neoadjuvant and adjuvant therapies for rectal cancer. How many patients are actually recruited in multimodality therapy concepts? An analysis of the Tumour Centre Schwerin].
    Zentralblatt fur Chirurgie, 2009, Volume: 134, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cancer Care Facilities; Chemotherapy, Adjuvant; Comb

2009
Recommendation preoperative 5-FU/RT fir T1-3, N0 disease.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2003, Volume: 1, Issue:3

    Topics: Algorithms; Antineoplastic Agents; Combined Modality Therapy; Fluorouracil; Humans; Practice Guideli

2003
Effects of preoperative chemoradiotherapy on anal sphincter functions and quality of life in rectal cancer patients.
    International journal of colorectal disease, 2010, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant;

2010
[Metachronous metastasis from rectal adenocarcinoma to the penis--case report].
    Magyar onkologia, 2009, Volume: 53, Issue:3

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Comb

2009
NCCN guideline updates: colon and rectal cancers, version 1.2004.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2004, Volume: 2, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Com

2004
Preoperative chemoradiotherapy does not necessarily reduce lymph node retrieval in rectal cancer specimens--results from a prospective evaluation with extensive pathological work-up.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2010, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2010
Locally recurrent rectal cancer: prognostic factors and long-term outcomes of multimodal therapy.
    Annals of surgical oncology, 2010, Volume: 17, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

2010
[A case of liver metastasis of rectal cancer, refractory to previous chemotherapy(5-FU/LV, irinotecan, oxaliplatin) responding to bevacizumab combined with FOLFIRI chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:10

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agen

2009
Thymidine phosphorylase to dihydropyrimidine dehydrogenase ratio as a predictive factor of response to preoperative chemoradiation with capecitabine in patients with advanced rectal cancer.
    Journal of surgical oncology, 2010, Oct-01, Volume: 102, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant;

2010
Neoadjuvant chemoradiotherapy with capecitabine followed by laparoscopic resection in locally advanced tumors of middle and low rectum - toxicity and complications of the treatment.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2010, Volume: 36, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Colectomy; Deoxycytid

2010
Chemoradiotherapy in the management of primary squamous-cell carcinoma of the rectum.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2011, Volume: 13, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy,

2011
Clinically-staged T3N0 rectal cancer: is preoperative chemoradiotherapy the optimal treatment?
    Annals of surgical oncology, 2010, Volume: 17, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

2010
[Two cases of advanced rectal cancer resected successfully after neoadjuvant chemotherapy with FOLFOX regimen].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucovorin; Male; Midd

2009
[Assessment of chemoradiation therapy for advanced rectal cancer invaded the pelvic organ].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Adenocarcinoma, Mucinous; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modalit

2009
[A case report of metastatic liver tumor from rectosigmoid colon cancer demonstrating a pathological complete response with FOLFOX and FOLFIRI treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothec

2009
[A case of liver metastasis of rectal cancer demonstrating complete response for more than two years to mFOLFOX6].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; M

2009
[A case of advanced rectal cancer with severe liver dysfunction due to multiple liver metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Hepatic Artery; Humans; Infusion

2009
[Two case reports of metastatic liver carcinoma with the effective treatment of radiofrequency ablation and intraarterial chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Aged; Catheter Ablation; Combined Modality Therapy; Esophageal Neoplasms; Fluorouracil; Humans; Infu

2009
[A case of surgical approach to the recurrence of the para-aortic lymph nodes after resection of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta, Abdominal; Combined Modality Therapy; Female;

2009
High-grade acute organ toxicity during preoperative radiochemotherapy as positive predictor for complete histopathologic tumor regression in multimodal treatment of locally advanced rectal cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2010, Volume: 186, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap

2010
Drug monitoring during FOLFOX6 therapy in a rectal cancer patient on chronic hemodialysis.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Chronic Disease; Drug Monitoring;

2010
[A case of advanced rectal cancer with liver and lung metastasis showing a complete response by neo-adjuvant FOLFOX4 chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemothe

2010
MGMT -535G>T polymorphism is associated with prognosis for patients with metastatic colorectal cancer treated with oxaliplatin-based chemotherapy.
    Journal of cancer research and clinical oncology, 2010, Volume: 136, Issue:8

    Topics: Amino Acid Substitution; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cape

2010
Complications after sphincter-saving resection in rectal cancer patients according to whether chemoradiotherapy is performed before or after surgery.
    International journal of radiation oncology, biology, physics, 2010, Sep-01, Volume: 78, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Anastomosis, Surgical; Antineoplastic Combined Chemotherapy

2010
Evaluation of early metabolic responses in rectal cancer during combined radiochemotherapy or radiotherapy alone: sequential FDG-PET-CT findings.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 94, Issue:2

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; De

2010
Gene expression profiles of epidermal growth factor receptor, vascular endothelial growth factor and hypoxia-inducible factor-1 with special reference to local responsiveness to neoadjuvant chemoradiotherapy and disease recurrence after rectal cancer surg
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2010, Volume: 22, Issue:4

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Combined Modality Therapy;

2010
[Herpes simplex virus bronchopneumonitis in patient with acute respiratory failure after surgery].
    Medicina intensiva, 2010, Volume: 34, Issue:2

    Topics: Acute Disease; Acyclovir; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antiviral Agents; B

2010
Thymidylate synthase germline polymorphisms in rectal cancer patients treated with neoadjuvant chemoradiotherapy based on 5-fluorouracil.
    Journal of cancer research and clinical oncology, 2010, Volume: 136, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Base Sequence; Combined Modality Th

2010
Patient-reported acute gastrointestinal symptoms during concurrent chemoradiation treatment for rectal cancer.
    Cancer, 2010, Apr-15, Volume: 116, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Diarrhea; Feasibility Studies

2010
Vascular endothelial growth factor gene polymorphisms in patients with colorectal cancer.
    Revista espanola de enfermedades digestivas, 2010, Volume: 102, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv

2010
Neoadjuvant chemotherapy in MRI-staged rectal cancer.
    The Lancet. Oncology, 2010, Volume: 11, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Humans; N

2010
Capecitabine initially concomitant to radiotherapy then perioperatively administered in locally advanced rectal cancer. In regard to MG Zampino et al. (Int J Radiat Oncol Biol Phys 2009;75:421-427).
    International journal of radiation oncology, biology, physics, 2010, Mar-15, Volume: 76, Issue:4

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fluorouraci

2010
Impact of tumor response on survival after radiochemotherapy in locally advanced rectal carcinoma.
    The American journal of surgical pathology, 2010, Volume: 34, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv

2010
Salvage surgery for locally recurrent rectal cancer: total mesorectal excision during the primary operation does not influence the outcome.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2011, Volume: 13, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Digestiv

2011
Impact of neoadjuvant treatment on total mesorectal excision for ultra-low rectal cancers.
    World journal of surgical oncology, 2010, Mar-26, Volume: 8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality T

2010
Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy.
    The pharmacogenomics journal, 2011, Volume: 11, Issue:3

    Topics: Adult; Aged; Female; Fluorouracil; Gene Expression Profiling; Genetic Association Studies; Genotype;

2011
[Treatment of advanced and/or metastatic colorectal cancer with bevacizumab in combination with oxaliplatin-based chemotherapy (Folfox7 regimen)].
    Bulletin du cancer, 2010, Volume: 97, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
Stage II/III rectal cancer with intermediate response to preoperative radiochemotherapy: do we have indications for individual risk stratification?
    World journal of surgical oncology, 2010, Apr-13, Volume: 8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clin

2010
Role of neo-adjuvant chemoradiation in locally advanced rectal cancers.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2010, Volume: 20, Issue:3

    Topics: Chemotherapy, Adjuvant; Fluorouracil; Humans; Immunosuppressive Agents; Infusions, Intravenous; Leuc

2010
Correlations of clinicopathological factors with protein expression levels of thymidylate synthase, dihydropyrimidine dehydrogenase and orotate phosphoribosyltransferase in colorectal cancer.
    Chemotherapy, 2010, Volume: 56, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Dihydrouracil Dehydrogenase (NADP); Female; Fluor

2010
[Drug eruption (erythema multiforme type) following chemoradiotherapy with mitomycin C and 5-fluorouracil administration for squamous cell carcinoma of the anal canal].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:4

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modal

2010
[Pathologically complete response of multiple liver metastases from rectal cancer treated with mFOLFOX6 plus bevacizumab].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2010, Volume: 107, Issue:5

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Comb

2010
Oxaliplatin plus dual inhibition of thymidilate synthase during preoperative pelvic radiotherapy for locally advanced rectal carcinoma: long-term outcome.
    International journal of radiation oncology, biology, physics, 2011, Mar-01, Volume: 79, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2011
Anal function and intersphincteric resection.
    Diseases of the colon and rectum, 2010, Volume: 53, Issue:6

    Topics: Adenocarcinoma; Anal Canal; Antineoplastic Agents; Combined Modality Therapy; Fluorouracil; Humans;

2010
Circulating lymphocyte number has a positive association with tumor response in neoadjuvant chemoradiotherapy for advanced rectal cancer.
    Radiation oncology (London, England), 2010, Jun-03, Volume: 5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Ther

2010
[A case or resection of synchronous multiple liver metastases from rectal cancer after FOLFOX4 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Liver Neopla

2010
[Elderly patient with recurrent rectal cancer successfully responded to modified FOLFOX6 chemotherapy with bevacizumab--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:6

    Topics: Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combine

2010
Sexual function in females after radiotherapy for rectal cancer.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coitus; Cross-S

2010
Preoperative chemoradiotherapy for rectal cancer: a comparison between intravenous 5-fluorouracil and oral capecitabine.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2010, Volume: 12 Suppl 2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine;

2010
Development of bronchiolitis obliterans organizing pneumonia with platinum-based chemotherapy for metastatic rectal cancer.
    Clinical colorectal cancer, 2010, Volume: 9, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Com

2010
[Efficacy observation of accelerated hyperfractionation recourse radiotherapy plus concurrent capecitabine in the treatment of locoregional recurrent rectal cancer].
    Zhonghua yi xue za zhi, 2010, Apr-13, Volume: 90, Issue:14

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Dose Fractionation, Radia

2010
[Two cases of unstable angina in patients treated with bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:7

    Topics: Aged; Angina, Unstable; Angiogenesis Inhibitors; Angiography; Antibodies, Monoclonal; Antibodies, Mo

2010
Preoperative chemoradiation for rectal cancer using capecitabine and celecoxib correlated with posttreatment assessment of thymidylate synthase and thymidine phosphorylase expression.
    International journal of radiation oncology, biology, physics, 2011, Aug-01, Volume: 80, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cape

2011
Prediction of response to preoperative chemoradiotherapy in rectal cancer by multiplex kinase activity profiling.
    International journal of radiation oncology, biology, physics, 2010, Oct-01, Volume: 78, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidi

2010
Radiosensitizing drugs: lessons to be learned from the oxaliplatin story.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Oct-10, Volume: 28, Issue:29

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined Modal

2010
Are we ready to use an early alternative end point as the primary end point of a phase III study in rectal cancer?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Oct-10, Volume: 28, Issue:29

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Clinical Trial

2010
Patterns of response after preoperative intensity-modulated radiation therapy and capecitabine/oxaliplatin in rectal cancer: is there still a place for ecoendoscopic ultrasound?
    International journal of radiation oncology, biology, physics, 2011, Oct-01, Volume: 81, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deox

2011
Preliminary experience with bladder preservation for lower rectal cancers involving the lower urinary tract.
    Journal of surgical oncology, 2010, Dec-01, Volume: 102, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Feasibility

2010
[Two cases of colorectal cancer presenting with periodic, transient elevation of serum iron due to hemolysis after chemotherapy including 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:9

    Topics: Aged; Bilirubin; Colonic Neoplasms; Female; Fluorouracil; Hemolysis; Humans; Iron; Male; Middle Aged

2010
Prognostic role of EGFR gene copy number and KRAS mutation in patients with locally advanced rectal cancer treated with preoperative chemoradiotherapy.
    British journal of cancer, 2010, Sep-28, Volume: 103, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; ErbB Receptors;

2010
Outcome standards for an organ preservation strategy in stage II and III rectal adenocarcinoma after neoadjuvant chemoradiation.
    Annals of surgical oncology, 2011, Volume: 18, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoth

2011
Prospective study on the FDG-PET/CT predictive and prognostic values in patients treated with neoadjuvant chemoradiation therapy and radical surgery for locally advanced rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorodeox

2011
Perirenal hematoma associated with bevacizumab treatment.
    Investigational new drugs, 2012, Volume: 30, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2012
Thymidylate synthase gene polymorphism affects the response to preoperative 5-fluorouracil chemoradiation therapy in patients with rectal cancer.
    International journal of radiation oncology, biology, physics, 2011, Nov-01, Volume: 81, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Female; Fluorouraci

2011
A retrospective observational study on the safety and efficacy of first-line treatment with bevacizumab combined with FOLFIRI in metastatic colorectal cancer.
    British journal of cancer, 2010, Nov-09, Volume: 103, Issue:10

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2010
Criteria for three-dimensional anorectal ultrasound assessment of response to chemoradiotherapy in rectal cancer patients.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2011, Volume: 13, Issue:12

    Topics: Adenocarcinoma; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy,

2011
A gene expression signature for chemoradiosensitivity of colorectal cancer cells.
    International journal of radiation oncology, biology, physics, 2010, Nov-15, Volume: 78, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Surviv

2010
L-type amino-acid transporter 1 expression predicts the response to preoperative hyperthermo-chemoradiotherapy for advanced rectal cancer.
    Anticancer research, 2010, Volume: 30, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Biopsy; Cell Membrane; Fluorouracil; Humans; Hyperthermia, Induced; Lar

2010
Imunoexpression of Ki-67 and p53 in rectal cancer tissue after treatment with neoadjuvant chemoradiation.
    Journal of gastrointestinal cancer, 2011, Volume: 42, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Mo

2011
A bilateral cicatricial ectropion and bilateral upper lid shortening caused by 5-fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency.
    Cutaneous and ocular toxicology, 2011, Volume: 30, Issue:2

    Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma; Dihydropyrimidine Dehydrogenase Defic

2011
[Successful treatment with cetuximab combination chemotherapy in a case of FOLFOX-refractory rectal cancer with previously unresectable multiple liver metastases leading to complete resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:11

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplas

2010
Predictive factors of tumor response after neoadjuvant chemoradiation for locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2011, Jun-01, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Carcinoembryonic Anti

2011
Standard-dose tegafur combined with uracil is not safe treatment after severe toxicity from 5-fluorouracil or capecitabine.
    Annals of internal medicine, 2010, Dec-07, Volume: 153, Issue:11

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Dihydropyrimidine Dehydrogenase Defici

2010
Patient-reported outcomes after neoadjuvant chemoradiotherapy for rectal cancer: a multicenter prospective observational study.
    Annals of surgery, 2011, Volume: 253, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Dose Fractionation, Radiation

2011
Hepar lobatum carcinomatosum associated with metastatic rectal carcinoma: an unusual cause of liver dysmorphy.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2011, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Liver; Liver Neoplasms; Male;

2011
[A case of liver metastases from rectal cancer showed a complete response by FOLFIRI and bevacizumab chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:13

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C

2010
X-ray cross-complementing group 1 and thymidylate synthase polymorphisms might predict response to chemoradiotherapy in rectal cancer patients.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy;

2012
Complete clinical response after neoadjuvant chemoradiation therapy for distal rectal cancer: characterization of clinical and endoscopic findings for standardization.
    Diseases of the colon and rectum, 2010, Volume: 53, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Endoscopy, Gastrointestinal; Female; Fluorouracil; Huma

2010
Complete clinical response after neoadjuvant chemoradiation therapy for distal rectal cancer: characterization of clinical and endoscopic findings for standardization.
    Diseases of the colon and rectum, 2010, Volume: 53, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Endoscopy, Gastrointestinal; Female; Fluorouracil; Huma

2010
Complete clinical response after neoadjuvant chemoradiation therapy for distal rectal cancer: characterization of clinical and endoscopic findings for standardization.
    Diseases of the colon and rectum, 2010, Volume: 53, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Endoscopy, Gastrointestinal; Female; Fluorouracil; Huma

2010
Complete clinical response after neoadjuvant chemoradiation therapy for distal rectal cancer: characterization of clinical and endoscopic findings for standardization.
    Diseases of the colon and rectum, 2010, Volume: 53, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Endoscopy, Gastrointestinal; Female; Fluorouracil; Huma

2010
Laparoscopic proctectomy after neoadjuvant therapy: safety and long-term follow-up.
    Surgical endoscopy, 2011, Volume: 25, Issue:6

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Digestive System Surgi

2011
Adjuvant 5-fluorouracil-induced colitis necessitating completion colectomy.
    Journal of gastrointestinal cancer, 2011, Volume: 42, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colectomy; Colitis; Fluorou

2011
Risk-adapted adjuvant chemotherapy after concomitant fluoropyrimidine-radiotherapy neoadjuvant treatment for patients with resectable cT3-4 or N+ rectal cancer.
    Anti-cancer drugs, 2011, Volume: 22, Issue:2

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol

2011
[Long-term control of sacral metastasis from rectal cancer with S-1 + radiation treatment (RT) and mFOLFOX6 combination therapy--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Dru

2010
[A case with liver resection of metastasis from rectal cancer after bevacizumab treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C

2010
[The efficacy of cetuximab for metastatic colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplast

2010
[Two cases of venous thrombosis confirmed during the bevacizumab combination chemotherapy for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Aged; Angiogenesis Inducing Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antin

2010
[A long-term survival case of rectal cancer with Virchow's lymph node metastasis by multimodality therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2010
[Idiopathic thrombocytopenic purpura during chemotherapy for liver metastasis of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C

2010
[A long-term disease-free survival case of advanced rectal cancer with massive metastasis to the lateral pelvic and para-aortic lymph nodes].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined C

2010
[A case of successfully treated lower rectal cancer with both inguinal lymph nodes by chemoradiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized;

2010
[A case report of advanced rectal cancer showing a pathological complete response by neo-adjuvant FOLFOX chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovor

2010
[A case of rectal cancer with synchronous multiple liver metastases successfully treated with combined chemotherapy of modified FOLFOX6 and bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C

2010
[Long-term survival case after liver resection and postoperative hepatic arterial infusion for multiple liver metastases from rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Antimetabolites, Antineoplastic; Disease-Free Survival; Fluorouracil; Hepatectomy; Humans; Infusions

2010
Rectal cancer: mucinous carcinoma on magnetic resonance imaging indicates poor response to neoadjuvant chemoradiation.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma

2012
Toxicity and complications of preoperative chemoradiotherapy for locally advanced rectal cancer.
    The British journal of surgery, 2011, Volume: 98, Issue:3

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemot

2011
5-FU-induced hyperammonemic encephalopathy in a case of metastatic rectal adenocarcinoid successfully rechallenged with the fluoropyrimidine analog, capecitabine.
    Anticancer research, 2011, Volume: 31, Issue:1

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Brain Diseases; Capecitabine; Deoxycytidine;

2011
Postoperative low pelvic radiotherapy and chemotherapy for stage II and III rectal cancer.
    American journal of clinical oncology, 2012, Volume: 35, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Drug Admin

2012
Stage-to-stage comparison of preoperative and postoperative chemoradiotherapy for T3 mid or distal rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemorad

2012
Mucinous rectal cancer: effectiveness of preoperative chemoradiotherapy and prognosis.
    Annals of surgical oncology, 2011, Volume: 18, Issue:8

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol

2011
Diffusion-weighted MRI for selection of complete responders after chemoradiation for locally advanced rectal cancer: a multicenter study.
    Annals of surgical oncology, 2011, Volume: 18, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemor

2011
Diffusion-weighted MRI for selection of complete responders after chemoradiation for locally advanced rectal cancer: a multicenter study.
    Annals of surgical oncology, 2011, Volume: 18, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemor

2011
Diffusion-weighted MRI for selection of complete responders after chemoradiation for locally advanced rectal cancer: a multicenter study.
    Annals of surgical oncology, 2011, Volume: 18, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemor

2011
Diffusion-weighted MRI for selection of complete responders after chemoradiation for locally advanced rectal cancer: a multicenter study.
    Annals of surgical oncology, 2011, Volume: 18, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemor

2011
[Effective cetuximab monotherapy for a case of recurrence rectal cancer after multiple previous chemotherapy treatment (FOLFOX, FOLFIRI)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2011
[A case of unresectable rectal cancer with severe pelvic infiltration responding to FOLFOX].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Leu

2011
Accelerated hyperfractionation field-involved re-irradiation combined with concurrent capecitabine chemotherapy for locally recurrent and irresectable rectal cancer.
    The British journal of radiology, 2012, Volume: 85, Issue:1011

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidine; Diseas

2012
An evaluation of whether neoadjuvant therapy delays closure of defunctioning loop ileostomy following anterior resection for rectal cancer.
    Minerva chirurgica, 2011, Volume: 66, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antimetabolites, Antineoplast

2011
Value of diffusion-weighted magnetic resonance imaging for prediction and early assessment of response to neoadjuvant radiochemotherapy in rectal cancer: preliminary results.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Diffus

2012
Circulating cell-free DNA: a promising marker of pathologic tumor response in rectal cancer patients receiving preoperative chemoradiotherapy.
    Annals of surgical oncology, 2011, Volume: 18, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carb

2011
The predictive role of sequential FDG-PET/CT in response of locally advanced rectal cancer to neoadjuvant chemoradiation.
    American journal of clinical oncology, 2012, Volume: 35, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Fema

2012
Neoadjuvant radiochemotherapy and surgery for advanced rectal cancer : prognostic significance of tumor regression.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:4

    Topics: Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcin

2011
Evaluation of ¹⁸F-FDG-PET for early detection of suboptimal response of rectal cancer to preoperative chemoradiotherapy: a prospective analysis.
    Annals of surgical oncology, 2011, Volume: 18, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Fema

2011
Rectal motion in patients receiving preoperative radiotherapy for carcinoma of the rectum.
    International journal of radiation oncology, biology, physics, 2011, May-01, Volume: 80, Issue:1

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Contrast Media; Fluorouracil; Humans; Mo

2011
[Ileitis following capecitabine use].
    Nederlands tijdschrift voor geneeskunde, 2011, Volume: 155

    Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Ileitis; M

2011
MRI-based indications for neoadjuvant radiochemotherapy in rectal carcinoma: interim results of a prospective multicenter observational study.
    Annals of surgical oncology, 2011, Volume: 18, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape

2011
Clinical significance of pre- to post-chemoradiotherapy s-CEA reduction ratio in rectal cancer patients treated with preoperative chemoradiotherapy and curative resection.
    Annals of surgical oncology, 2011, Volume: 18, Issue:12

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabin

2011
Gender-specific acute organ toxicity during intensified preoperative radiochemotherapy for rectal cancer.
    The oncologist, 2011, Volume: 16, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Com

2011
A case of heavily pretreated rectal cancer with disseminated intravascular coagulation that improved following reintroduction of FOLFOX plus bevacizumab.
    International journal of clinical oncology, 2011, Volume: 16, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Diss

2011
Short-course versus standard chemoradiation in T3 rectal cancer.
    The oncologist, 2011, Volume: 16, Issue:5

    Topics: Adenocarcinoma; Aged; Female; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm Staging; Radiation

2011
Tumor volume reduction rate after preoperative chemoradiotherapy as a prognostic factor in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camp

2012
Combination of differentiation and T stage can predict unresponsiveness to neoadjuvant therapy for rectal cancer.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2011, Volume: 13, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Disease-Free Surv

2011
The use of molecular markers as a method to predict the response to neoadjuvant therapy for advanced stage rectal adenocarcinoma.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2012, Volume: 14, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Apoptotic Protease-

2012
[Successful chemotherapy of carcinomatosis of the bone marrow with disseminated intravascular coagulation from a rectal carcinoma found by eosinophilia].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2011, Volume: 108, Issue:7

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Carcino

2011
Clinical outcomes of mild hyperthermia for locally advanced rectal cancer treated with preoperative radiochemotherapy.
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2011, Volume: 27, Issue:5

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemotherapy, Adj

2011
[Eighty-five-year-old patient with recurrent rectal cancer effectively treated with CapeOX chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:7

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Capecitabine; Deo

2011
[A case of advanced rectal cancer resected successfully after preoperative XELOX chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deox

2011
Adjuvant modified FOLFOX-4 in patients with stage III rectum adenocarcinoma.
    Asian Pacific journal of cancer prevention : APJCP, 2011, Volume: 12, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chem

2011
[Effect of the duration of time between chemo-radiotherapy and surgical intervention on the results of the combined treatment of rectal cancer].
    Voprosy onkologii, 2011, Volume: 57, Issue:2

    Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cis

2011
Accuracy of endoscopic ultrasound to assess tumor response after neoadjuvant treatment in rectal cancer: can we trust the findings?
    Diseases of the colon and rectum, 2011, Volume: 54, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Colonoscopy; Endosonography;

2011
[Pilot study of preoperative mFOLFOX6 chemotherapy for advanced rectal cancers which were difficult to ensure surgical margins].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Leu

2011
A single-centre experience of chemoradiotherapy for rectal cancer: is there potential for nonoperative management?
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2012, Volume: 14, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; De

2012
The prognostic value of grade of regression and oncocytic change in rectal adenocarcinoma treated with neo-adjuvant chemoradiotherapy.
    Journal of surgical oncology, 2012, Volume: 105, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2012
Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy.
    BMC cancer, 2011, Aug-19, Volume: 11

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2011
[Neoadjuvant radiochemotherapy for rectal cancer].
    MMW Fortschritte der Medizin, 2011, Sep-01, Volume: 153, Issue:35

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Fluorouracil; Hu

2011
[A resected case of locally invasive rectal cancer successfully treated with neoadjuvant capecitabine, oxaliplatin, bevacizumab and radiation therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2011
Molecular changes consistent with increased proliferation and invasion are common in rectal cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2011, Volume: 13, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Case-Control Stu

2011
The effect of postoperative pelvic irradiation after complete resection of metastatic rectal cancer.
    Journal of surgical oncology, 2012, Volume: 105, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Ch

2012
TS and DPD mRNA levels on formalin-fixed paraffin-embedded specimens as predictors for distant recurrence of rectal cancer treated with preoperative chemoradiotherapy.
    Journal of surgical oncology, 2012, Volume: 105, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Dihydrouracil Dehydrogenase (NADP);

2012
Securin identifies a subgroup of patients with poor outcome in rectal cancer treated with long-course (chemo)radiotherapy.
    Acta oncologica (Stockholm, Sweden), 2011, Volume: 50, Issue:8

    Topics: Aged; Antimetabolites, Antineoplastic; Biopsy; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine;

2011
The differential impact of microsatellite instability as a marker of prognosis and tumour response between colon cancer and rectal cancer.
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Colonic Neoplasms; Female; Fluorouracil; Humans;

2012
Prognostic significance of glucose transporter-1 (GLUT1) gene expression in rectal cancer after preoperative chemoradiotherapy.
    Surgery today, 2012, Volume: 42, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Line, Tumor; Ch

2012
Total mesorectal excision of initially unresectable locally advanced rectal cancer infiltrating the pelvic wall after treatment with FOLFOX4 plus bevacizumab and preoperative chemoradiation: report of a case.
    Surgery today, 2012, Volume: 42, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Chem

2012
Tumor response and negative distal resection margins of rectal cancer after hyperthermochemoradiation therapy.
    Anticancer research, 2011, Volume: 31, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

2011
Safety and outcome of chemoradiotherapy in elderly patients with rectal cancer: results from two French tertiary centres.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycyti

2012
Pathologic complete response after FOLFOX7 in a locally advanced rectal cancer.
    Journal of clinical gastroenterology, 2012, Volume: 46, Issue:1

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Flu

2012
A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, Jul-15, Volume: 83, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Biopsy; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine

2012
[A case of recurrent rectal cancer with paraaortic lymph node metastasis treated by FOLFIRI therapy leading to complete response].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Camptothecin; Female; Fluorouracil; Humans; L

2011
[A case of metastatic rectal cancer in an extremely aged patient successfully treated with mFOLFOX6 plus bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combin

2011
[Repeated resections for originally unresectable liver metastasis from colorectal cancer after multiagent chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemothera

2011
[A case of colon cancer with long-term survival treated by resection of recurrence on the rectum and chemotherapy for lung metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Fluorouracil; Humans; Leucov

2011
[A case of no recurrence over 10 years in advanced rectal cancer with bleeding treated by urgent arterial embolization followed by synchronous liver resection and extended lymph node dissection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Chemoembolization, Therapeutic; Combined Modality Therapy; Fe

2011
[Diffusion-weighted MR imaging in patients with rectal cancer: our initial experience].
    Acta gastroenterologica Latinoamericana, 2011, Volume: 41, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Diffusion Magnetic Resonance Imagin

2011
Optimal lymph node harvest in rectal cancer (UICC stages II and III) after preoperative 5-FU-based radiochemotherapy. Acetone compression is a new and highly efficient method.
    The American journal of surgical pathology, 2012, Volume: 36, Issue:2

    Topics: Acetone; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy; Female;

2012
A observational study of the efficacy and safety of capecitabine versus bolus infusional 5-fluorouracil in pre-operative chemoradiotherapy for locally advanced rectal cancer.
    International journal of colorectal disease, 2012, Volume: 27, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Deoxycytidin

2012
"The only thing I know is that I know nothing": 5-fluorouracil in human milk.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:2

    Topics: Adult; Antimetabolites, Antineoplastic; Breast Feeding; Chromatography, High Pressure Liquid; Female

2012
In regard to "Thymidylate synthase gene polymorphism affects the response to preoperative 5-fluorouracil chemoradiation therapy in patients with rectal cancer" (Int J Radiat Oncol Biol Phys 2011;81:669-676).
    International journal of radiation oncology, biology, physics, 2012, Mar-01, Volume: 82, Issue:3

    Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy; Female; Fluorouracil; Humans; Male; Polymorphism

2012
Adjuvant chemotherapy with or without pelvic radiotherapy after simultaneous surgical resection of rectal cancer with liver metastases: analysis of prognosis and patterns of recurrence.
    International journal of radiation oncology, biology, physics, 2012, Sep-01, Volume: 84, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Deoxycyt

2012
Combined modality therapy for rectal cancer: the relative value of posttreatment versus pretreatment CEA as a prognostic marker for disease recurrence.
    Annals of surgical oncology, 2012, Volume: 19, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; C

2012
[Huge unresectable multiple hepatic metastases of rectum cancer responding to combined therapy with FOLFIRI +bevacizumab - a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biop

2012
Development of a standardized method for contouring the lumbosacral plexus: a preliminary dosimetric analysis of this organ at risk among 15 patients treated with intensity-modulated radiotherapy for lower gastrointestinal cancers and the incidence of rad
    International journal of radiation oncology, biology, physics, 2012, Oct-01, Volume: 84, Issue:2

    Topics: Anatomic Landmarks; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Fluorouracil; Hu

2012
Intensified neoadjuvant chemoradiotherapy in locally advanced rectal cancer -- impact on long-term quality of life.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2012, Volume: 38, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2012
Response of glutathione S-transferase Pi (GSTP1) to neoadjuvant therapy in rectal adenocarcinoma.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2012, Volume: 14, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; F

2012
Predicting pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer using 18FDG-PET/CT.
    Annals of surgical oncology, 2012, Volume: 19, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemor

2012
Simultaneous neoadjuvant radiochemotherapy with capecitabine and oxaliplatin for locally advanced rectal cancer. Treatment outcome outside clinical trials.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2012, Volume: 188, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deoxycy

2012
Severe hypertriglyceridaemia associated with the use of capecitabine.
    The Netherlands journal of medicine, 2012, Volume: 70, Issue:2

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Hypertriglycerid

2012
[A case of resected rectal cancer with hepatic node and multiple liver metastases effectively treated by preoperative modified FOLFOX6 and sLV5FU2 chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Human

2012
MR imaging of rectal cancer before and after chemoradiation therapy.
    La Radiologia medica, 2012, Volume: 117, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Fema

2012
Dose--volume effects on patient-reported acute gastrointestinal symptoms during chemoradiation therapy for rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, Jul-15, Volume: 83, Issue:4

    Topics: Aged; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Defecation; Deoxycytidine; Diarrhea; F

2012
Impact of interval between neoadjuvant chemoradiotherapy and TME for locally advanced rectal cancer on pathologic response and oncologic outcome.
    Annals of surgical oncology, 2012, Volume: 19, Issue:9

    Topics: Adenocarcinoma; Aged; Anastomotic Leak; Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant

2012
Evaluation of the efficacy of modified De Gramont and modified FOLFOX4 regimens for adjuvant therapy of locally advanced rectal cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2011, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemorad

2011
Induction chemotherapy with capecitabine and oxaliplatin followed by chemoradiotherapy before total mesorectal excision in patients with locally advanced rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidi

2012
Short-term results and long-term oncologic outcomes between neoadjuvant chemoradiotherapy and adjuvant postoperative chemoradiotherapy for stage III rectal cancer: a case-matched study.
    Annals of surgical oncology, 2012, Volume: 19, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Chemoradiotherapy; Female; Flu

2012
[Role of pharmacokinetic monitoring of serum fluorouracil concentration in patients with local advanced and metastatic colorectal cancer and further improving efficacy of fluorouracil-based chemotherapy].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2012, Volume: 34, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol

2012
[A case of rectal hemorrhage during chemotherapy with bevacizumab for local recurrence of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:4

    Topics: Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols

2012
[Complete clinical and pathological response to mFOLFOX6 neoadjuvant chemotherapy in a case of advanced rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucovorin; Neoa

2012
[A case of locally advanced rectal cancer had a pathological complete response to XELOX Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoembryonic Antigen; Deoxycytidin

2012
Hand-foot syndrome related to chemotherapy.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2012, Oct-16, Volume: 184, Issue:15

    Topics: Antineoplastic Agents; Capecitabine; Deoxycytidine; Female; Fluorouracil; Hand-Foot Syndrome; Humans

2012
[A case of remnant liver metastases after resection of liver metastases from rectal cancer following treatment with 5-FU, L-OHP and CPT-11, with markedly effective treatment by cetuximab plus S-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:5

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2012
Lymph node retrieval after preoperative chemoradiotherapy for rectal cancer.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy,

2012
Long-term results with oral fluoropyrimidines and oxaliplatin-based preoperative chemoradiotherapy in patients with resectable rectal cancer. A single-institution experience.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2012, Volume: 14, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Drug Administration

2012
Capecitabine in the treatment of rectal cancer.
    The Lancet. Oncology, 2012, Volume: 13, Issue:6

    Topics: Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans;

2012
[A case of response to panitumumab as third-line chemotherapy for multiple liver metastases and portal venal tumor embolus of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:6

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Embol

2012
[A case report of pathologically complete response of locally advanced rectal cancer after neoadjuvant chemoradiotherapy with XELOX and bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:6

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab

2012
Squamous cell carcinoma of the rectum: a single institution experience.
    Techniques in coloproctology, 2012, Volume: 16, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; C

2012
[Increased INR from concomitant use of acenocoumarol and capecitabine].
    Nederlands tijdschrift voor geneeskunde, 2012, Volume: 156, Issue:26

    Topics: Acenocoumarol; Aged, 80 and over; Anticoagulants; Antimetabolites, Antineoplastic; Atrial Fibrillati

2012
[Evaluation of modified OPTIMOX1 plus bevacizumab as the neoadjuvant therapy for highly advanced rectal cancers].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:7

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Che

2012
Concurrent chemoradiotherapy followed by metastasectomy converts to survival benefit in stage IV rectum cancer.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012, Volume: 16, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camp

2012
Early prediction of histopathological response of rectal tumors after one week of preoperative radiochemotherapy using 18 F-FDG PET-CT imaging. A prospective clinical study.
    Radiation oncology (London, England), 2012, Aug-01, Volume: 7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothe

2012
Is restaging with chest and abdominal CT scan after neoadjuvant chemoradiotherapy for locally advanced rectal cancer necessary?
    Annals of surgical oncology, 2013, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; De

2013
Oncologically safe distal resection margins in rectal cancer patients treated with chemoradiotherapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012, Volume: 16, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2012
Use of adjuvant chemotherapy in stage C (III) rectal cancer: comparison of data from matched patients in a teaching hospital's clinico-pathological database.
    Asia-Pacific journal of clinical oncology, 2012, Volume: 8, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2012
[A case of huge advanced rectal cancer resected successfully after chemotherapy with mFOLFOX6].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Combined Modality Therapy; Female; Flu

2012
Prognostic significance of thymidylate synthase polymorphisms in rectal cancer patients treated with neoadjuvant chemoradiotherapy.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2013, Volume: 15, Issue:4

    Topics: 3' Untranslated Regions; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy

2013
Molecular markers predict distant metastases after adjuvant chemoradiation for rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, Dec-01, Volume: 84, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Chemoradiotherapy,

2012
[A case of adenocarcinoma occurring at colostomy site 7 years after abdominoperineal resection for rectal cancer resected after preoperative mFOLFOX6 chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:9

    Topics: Abdominal Wall; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Colost

2012
In regard to Samuelian et Al.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Antineoplastic Agents; Data Interpretation, Statistical; Diarrhea; Fluorouracil; Humans; Postoperati

2012
Pathological complete response and sphincter-sparing surgery after neoadjuvant radiochemotherapy with regional hyperthermia for locally advanced rectal cancer compared with radiochemotherapy alone.
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2012, Volume: 28, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy;

2012
Gene polymorphisms predict toxicity to neoadjuvant therapy in patients with rectal cancer.
    Cancer, 2013, Mar-01, Volume: 119, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemothe

2013
Bevacizumab-containing chemotherapy is safe in patients with unresectable metastatic colorectal cancer and a synchronous asymptomatic primary tumor.
    Japanese journal of clinical oncology, 2013, Volume: 43, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy

2013
[Evaluation of the efficacy and prognostic factors for colorectal liver metastases treated with transcatheter arterial chemoembolization].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2012, Volume: 34, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Tumor-Associated, Carbohydrate; Carcinoembryonic Antigen;

2012
MicroRNA expression profile associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients.
    Radiation oncology (London, England), 2012, Nov-20, Volume: 7

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Combi

2012
Small bowel dose parameters predicting grade ≥ 3 acute toxicity in rectal cancer patients treated with neoadjuvant chemoradiation: an independent validation study comparing peritoneal space versus small bowel loop contouring techniques.
    International journal of radiation oncology, biology, physics, 2013, Apr-01, Volume: 85, Issue:5

    Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Female; Fluorouracil; Humans; Intestin

2013
What is the incidence of metastatic lymph node involvement after significant pathologic response of primary tumor following neoadjuvant treatment for locally advanced rectal cancer?
    Annals of surgical oncology, 2013, Volume: 20, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, A

2013
Rectal cancer in pregnancy: a case report and review of the literature.
    Journal of gastrointestinal cancer, 2013, Volume: 44, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucovorin; Neo

2013
Transanal endoscopic microsurgery for residual rectal cancer (ypT0-2) following neoadjuvant chemoradiation therapy: another word of caution.
    Diseases of the colon and rectum, 2013, Volume: 56, Issue:1

    Topics: Adenocarcinoma; Aged; Anal Canal; Brazil; Chemoradiotherapy; Female; Fluorouracil; Humans; Male; Mic

2013
Which way is forward in the treatment of rectal cancer?
    Nature reviews. Clinical oncology, 2013, Volume: 10, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy;

2013
5-FU-induced cardiac toxicity--an underestimated problem in radiooncology?
    Radiation oncology (London, England), 2012, Dec-15, Volume: 7

    Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma; Cardiotoxins; Chemoradiotherapy; Electrocardiograp

2012
[Complete response obtained by preoperative chemotherapy in a case of T4 rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:12

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Comb

2012
[Two cases of interstitial pneumonia caused by cetuximab plus mFOLFOX6 therapy in metastatic colorectal cancer patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:12

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2012
[A case of advanced rectal cancer treated effectively with intersphincteric resection and preoperative chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Leu

2012
[A case of a colon cancer patient with liver metastasis subjected to hepatectomy after achieving radiographic complete response with preoperative chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Hepat

2012
[A case of advanced rectal cancer with lung and bone metastasis that was successfully treated with mFOLFOX6+bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:12

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone

2012
[A case report of recurrent lung metastasis after surgery for rectal cancer for which lung radiofrequency ablation therapy and long-term administration of FOLFIRI were effective].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Catheter Ablation; Fluorouracil; Human

2012
[A case report of successful treatment for rectosigmoid cancer with peritoneal dissemination after neoadjuvant chemoradiotherapy with XELOX and bevacizumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cape

2013
[A case of an ulcer of the sigmoid colon during chemotherapy with FOLFOX4 and bevacizumab for recurrence of rectal carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:1

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab

2013
[A case of advanced rectal cancer with bladder carcinoma salvaged from myocardial infarction during operation, showing tumor regression by XELOX treatment, good quality of life].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:1

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluo

2013
Impact of adjuvant chemoradiotherapy for rectal cancer on the long-term quality of life and late side effects: a multicentric clinical evaluation by the Turkish Oncology Group.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:11

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemora

2012
SKP2 overexpression is associated with a poor prognosis of rectal cancer treated with chemoradiotherapy and represents a therapeutic target with high potential.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:2

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor;

2013
Improved outcomes for rectal cancer in the era of preoperative chemoradiation and tailored mesorectal excision: a series of 338 consecutive cases.
    The American surgeon, 2013, Volume: 79, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antine

2013
Neoadjuvant therapy for rectal cancer decreases the number of lymph nodes harvested in operative specimens.
    American journal of surgery, 2013, Volume: 205, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy; Female; Fluorour

2013
Neoadjuvant oxaliplatin and 5-fluorouracil with concurrent radiotherapy in patients with locally advanced rectal cancer: a single-institution experience.
    La Radiologia medica, 2013, Volume: 118, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Combined Modality Therapy; Dose Fractionation

2013
Neoadjuvant therapy and mini-invasive total mesorectal excision for rectal cancer: feasibility and outcome analysis from a single institution prospectively collected data base.
    Tumori, 2012, Volume: 98, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2012
Pelvic radiation therapy combined with hepatic artery chemotherapy for resected rectal carcinoma with liver metastases.
    International journal of radiation oncology, biology, physics, 1996, Jan-01, Volume: 34, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Hepat

1996
Quantification of histologic regression of rectal cancer after irradiation: a proposal for a modified staging system.
    Diseases of the colon and rectum, 2002, Volume: 45, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouracil; Humans; Male;

2002
Long-term results of reirradiation for patients with recurrent rectal carcinoma.
    Cancer, 2002, Sep-01, Volume: 95, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

2002
Radio-chemotherapy as a preoperative treatment for advanced rectal cancer. Evaluation of down-staging and morbidity.
    Onkologie, 2002, Volume: 25, Issue:4

    Topics: Adult; Aged; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studi

2002
Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2002, Oct-01, Volume: 54, Issue:2

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplasti

2002
[A case of unresectable rectal cancer with liver and pulmonary metastases that responded remarkably to pharmacokinetic modulating chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:9

    Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Drug Administr

2002
Phenytoin toxicity as a result of 5-fluorouracil administration.
    The New Zealand medical journal, 2002, Aug-09, Volume: 115, Issue:1159

    Topics: Anticonvulsants; Antimetabolites, Antineoplastic; Drug Interactions; Epilepsy; Female; Fluorouracil;

2002
[A case of colon metastasis to the lung treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Sc

2002
Effect of preoperative radiochemotherapy on lymph node retrieval after resection of rectal cancer.
    Techniques in coloproctology, 2002, Volume: 6, Issue:2

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorouracil; Humans; Lymph Nodes; Preop

2002
Oral uracil/ftorafur (UFT) plus leucovorin as first-line chemotherapy and salvage therapy with weekly high-dose 5-fluorouracil/leucovorin for the treatment of metastatic colorectal cancer.
    Japanese journal of clinical oncology, 2002, Volume: 32, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; D

2002
Epidermal growth factor receptor is a predictor of tumor response in locally advanced rectal cancer patients treated with preoperative radiotherapy.
    International journal of radiation oncology, biology, physics, 2002, Dec-01, Volume: 54, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; ErbB Rec

2002
Epidermal growth factor receptor is a predictor of tumor response in locally advanced rectal cancer patients treated with preoperative radiotherapy.
    International journal of radiation oncology, biology, physics, 2002, Dec-01, Volume: 54, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; ErbB Rec

2002
Epidermal growth factor receptor is a predictor of tumor response in locally advanced rectal cancer patients treated with preoperative radiotherapy.
    International journal of radiation oncology, biology, physics, 2002, Dec-01, Volume: 54, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; ErbB Rec

2002
Epidermal growth factor receptor is a predictor of tumor response in locally advanced rectal cancer patients treated with preoperative radiotherapy.
    International journal of radiation oncology, biology, physics, 2002, Dec-01, Volume: 54, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; ErbB Rec

2002
[A case of locally extended rectal cancer responding to intra-arterial infusion therapy via the internal iliac artery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:12

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouraci

2002
[A case of metastatic vaginal tumor of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:12

    Topics: Adenocarcinoma; Combined Modality Therapy; Female; Fluorouracil; Humans; Hysterectomy; Middle Aged;

2002
Anal sphincter preservation in locally advanced low rectal adenocarcinoma after preoperative chemoradiation therapy and coloanal anastomosis.
    Journal of surgical oncology, 2003, Volume: 82, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Anastomosis, Surgical; Antimetabolites, Antineoplastic; Col

2003
A favourable pathological stage after neoadjuvant radiochemotherapy in patients with initially irresectable rectal cancer correlates with a favourable prognosis.
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:2

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Fluorouracil; Humans; Neoplasm Recurrence,

2003
Response to preoperative chemoradiation increases the use of sphincter-preserving surgery in patients with locally advanced low rectal carcinoma.
    Cancer, 2003, Jan-15, Volume: 97, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Agents; Combined Modality Therapy; Digest

2003
Prognostic role of serum vascular endothelial growth factor, basic fibroblast growth factor and nitric oxide in patients with colorectal carcinoma.
    Cytokine, 2002, Nov-24, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol

2002
Combined-modality therapy in locally advanced primary rectal cancer.
    Diseases of the colon and rectum, 2003, Volume: 46, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

2003
[The interest of radiotherapy in cancer of the rectum].
    Presse medicale (Paris, France : 1983), 2003, Feb-22, Volume: 32, Issue:7

    Topics: Chemotherapy, Adjuvant; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intravenous; Neo

2003
Distal intramural spread is an independent prognostic factor for distant metastasis and poor outcome in patients with rectal cancer: a multivariate analysis.
    Annals of surgical oncology, 2003, Volume: 10, Issue:2

    Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluoroura

2003
[Preoperative diagnostic procedures in locally advanced rectal carcinoma (> or =T3 or N+). What does endoluminal ultrasound achieve at staging and restaging (after neoadjuvant radiochemotherapy) in contrast to computed tomography?].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2003, Volume: 74, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality T

2003
Neoadjuvant systemic fluorouracil and mitomycin C prior to synchronous chemoradiation is an effective strategy in locally advanced rectal cancer.
    British journal of cancer, 2003, Apr-07, Volume: 88, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2003
Weekly hepatic arterial infusion of 5-fluorouracil and subsequent systemic chemotherapy for liver metastases from colorectal cancer.
    Japanese journal of clinical oncology, 2003, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic;

2003
Irinotecan (CPT11) plus high-dose 5-fluorouracil (5-FU) and leucovorin (LV) as salvage therapy for metastatic colorectal cancer (MCRC) after failed oxaliplatin plus 5-FU and LV: a pilot study in Taiwan.
    Japanese journal of clinical oncology, 2003, Volume: 33, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Adminis

2003
Longer time interval between completion of neoadjuvant chemoradiation and surgical resection does not improve downstaging of rectal carcinoma.
    Diseases of the colon and rectum, 2003, Volume: 46, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Ch

2003
[Clinical outcome of intra-hepatic arterial infusion therapy for multiple liver metastases from colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Colonic Neoplasms; Combined Modalit

2003
Physical training during intrahepatic chemotherapy.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Exercise Therapy; Fluorouracil; Forced Expiratory V

2003
Feasibility and morbidity of combined hyperthermia and radiochemotherapy in recurrent rectal cancer--preliminary results.
    Onkologie, 2003, Volume: 26, Issue:2

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease Progress

2003
Minidose warfarin is associated with a high incidence of International Normalized Ratio elevation during chemotherapy with FOLFOX regimen.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:6

    Topics: Adult; Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug

2003
Cardiac toxicity associated with capecitabine therapy.
    Acta oncologica (Stockholm, Sweden), 2003, Volume: 42, Issue:4

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diagnosis, Differential; Electrocardio

2003
The addition of continuous infusion 5-FU to preoperative radiation therapy increases tumor response, leading to increased sphincter preservation in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2003, Sep-01, Volume: 57, Issue:1

    Topics: Academic Medical Centers; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Chemotherapy,

2003
Isolated chemotherapeutic perfusion of the pelvis for advanced rectal cancer.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2003, Volume: 5, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheterization; Chemotherapy, Cancer,

2003
Capecitabine-related neurotoxicity presenting as trismus.
    Clinical colorectal cancer, 2003, Volume: 3, Issue:2

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Central Nervous System; Confusion; Deoxycytidine; Dia

2003
P27 does not predict histopathological response to radiochemotherapy in rectal cancer.
    The Journal of surgical research, 2003, Volume: 113, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Cell Cycle Proteins

2003
Response to preoperative chemoradiation in stage II and III rectal cancer.
    Diseases of the colon and rectum, 2003, Volume: 46, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil;

2003
5-Fluorouracil in the treatment of inoperable carcinoma of the colon and rectum.
    Cancer chemotherapy reports, 1962, Volume: 20

    Topics: Antineoplastic Agents; Carcinoma; Colonic Neoplasms; Fluorouracil; Humans; Rectal Neoplasms; Rectum;

1962
CHEMOTHERAPY OF METASTATIC LIVER CANCER BY PROLONGED HEPATIC-ARTERY INFUSION.
    The New England journal of medicine, 1964, Feb-13, Volume: 270

    Topics: Alkaline Phosphatase; Bile Duct Neoplasms; Bilirubin; Chemotherapy, Cancer, Regional Perfusion; Colo

1964
METHODOLOGY OF PRELIMINARY CHEMOTHERAPEUTIC TRIALS IN PATIENTS WITH MALIGNANT SOLID TUMORS.
    Cancer chemotherapy reports, 1963, Volume: 32

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Colonic Neoplasms; Cyclophosp

1963
PERCUTANEOUS VISCERAL CATHETERIZATION FOR INFUSION CANCER CHEMOTHERAPY.
    JAMA, 1964, Apr-20, Volume: 188

    Topics: Biomedical Research; Catheterization; Fluorouracil; Geriatrics; Humans; Injections, Intra-Arterial;

1964
VINCRISTINE (NSC-67574) THERAPY OF ADULT PATIENTS WITH SOLID TUMORS.
    Cancer chemotherapy reports, 1964, Volume: 34

    Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoid Tumor; Carcinoma, Bronchogenic; Carcinoma, Squamous

1964
FLUORINATED PYRIMIDINE THERAPY OF ADVANCED GASTROINTESTINAL CANCER.
    Gastroenterology, 1964, Volume: 46

    Topics: Alopecia; Colonic Neoplasms; Drug Eruptions; Esophagitis; Fluorouracil; Gallbladder Neoplasms; Human

1964
SERIAL ENZYME CHANGES IN CANCER PATIENTS UNDERGOING CHEMOTHERAPY.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Clinical Enzyme Tests; Colonic Neoplasms; D-Alani

1964
A REPORT OF THE SYSTEMIC USE OF 5-FLUOROURACIL IN THE TREATMENT OF CHINESE CANCER PATIENTS.
    British journal of cancer, 1964, Volume: 18

    Topics: Adenocarcinoma; Aged; Breast Neoplasms; Carcinoma; Carcinoma, Squamous Cell; China; Fallopian Tube N

1964
PALLIATIVE MANAGEMENT OF GASTROINTESTINAL CANCER.
    Canadian Medical Association journal, 1964, May-30, Volume: 90

    Topics: Adenocarcinoma; Ascites; Deglutition Disorders; Fluorouracil; Humans; Neoplasm Metastasis; Neoplasms

1964
TREATMENT OF MALIGNANT TUMOURS WITH 5-FLUOROURACIL IN 80 PATIENTS.
    Acta radiologica: therapy, physics, biology, 1964, Volume: 2

    Topics: Biomedical Research; Breast Neoplasms; Colonic Neoplasms; Drug Therapy; Esophageal Neoplasms; Female

1964
FLUOROURACIL COLON-RECTUM ADJUVANT CHEMOTHERAPY.
    Archives of surgery (Chicago, Ill. : 1960), 1964, Volume: 89

    Topics: Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Therapy; Fluorouracil; Humans; Infusions, Parenteral

1964
5-FLUOURACIL IN THE TREATMENT OF DISSEMINATED COLON AND RECTAL CARCINOMA.
    The New Zealand medical journal, 1964, Volume: 63

    Topics: Adenocarcinoma; Colonic Neoplasms; Fluorouracil; Geriatrics; Neoplasm Metastasis; Pharmacology; Rect

1964
REGIONAL INTRA-ARTERIAL INFUSION OF 5-FLUOROURACIL FOR CANCER.
    Surgery, 1964, Volume: 56

    Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Carcinoma, Squamous Cell; Female; Fluorouracil; Glioblast

1964
A LESS TOXIC FLUOROURACIL DOSAGE SCHEDULE.
    JAMA, 1964, Nov-16, Volume: 190

    Topics: Alopecia; Breast Neoplasms; Colonic Neoplasms; Diarrhea; Drug Eruptions; Epistaxis; Female; Floxurid

1964
STUDIES IN THE TOXICITY AND CLINICAL APPLICATION OF 5-FLUOROURACIL.
    The Medical journal of Australia, 1964, Oct-10, Volume: 2

    Topics: Adenocarcinoma; Agranulocytosis; Biomedical Research; Diarrhea; Diverticulitis; Drug Eruptions; Fluo

1964
COMBINED SPLIT-COURSE THERAPY WITH 5-FLUOROURACIL AND MEGAVOLTAGE IRRADIATION.
    Annales medicinae internae Fenniae, 1964, Volume: 53

    Topics: Colonic Neoplasms; Drug Therapy; Fluorouracil; Lung Neoplasms; Neoplasms; Radiography, Thoracic; Rad

1964
PELVIC PERFUSION AND CARCINOMA OF THE RECTUM.
    American journal of surgery, 1965, Volume: 109

    Topics: Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Equipment and Supplies; Fluorouracil; Humans; M

1965
TREATMENT OF MALIGNANT NEOPLASMS OF THE GASTROINTESTINAL TRACT WITH A COMBINATION OF 5-FLUOROURACIL AND RADIATION: A RANDOMIZED DOUBLE-BLIND STUDY.
    Radiology, 1965, Volume: 84

    Topics: Adenocarcinoma; Colonic Neoplasms; Double-Blind Method; Drug Therapy; Fluorouracil; Humans; Neoplasm

1965
COMPARISON OF 5-FLUOROURACIL (NSC-19893) AND 2'-DEOXY-5-FLUOROURIDINE (NSC-27640) IN TREATMENT OF PATIENTS WITH ADVANCED ADENOCARCINOMA OF COLON OR RECTUM.
    Cancer chemotherapy reports, 1965, Volume: 44

    Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Deoxyuridine; Drug Therapy; Fluorouracil;

1965
[Effectiveness of preoperative radio-chemo-thermotherapy with respect to thermometry in locally advanced rectal carcinoma].
    Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, 1998, Volume: 115, Issue:Suppl I

    Topics: Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluoroura

1998
Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Sep-15, Volume: 9, Issue:11

    Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic Neoplasms; Dihydrouracil Dehy

2003
Total cystectomies in the surgical treatment of rectal cancer with prior chemoradiation: analysis of postoperative morbidity and survival.
    International journal of colorectal disease, 2004, Volume: 19, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Cystecto

2004
Molecular pharmacology of cancer therapy in human colorectal cancer by gene expression profiling.
    Cancer research, 2003, Oct-15, Volume: 63, Issue:20

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Gene Expression;

2003
Catheter occlusion by calcium carbonate during simultaneous infusion of 5-FU and calcium folinate.
    Onkologie, 2003, Volume: 26, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Calcium Carbonate; Catheterization, Central Venous;

2003
[Male gonadal dose in adjuvant 3-d-pelvic irradiation after anterior resection of rectal cancer. Influence to fertility].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2003, Volume: 179, Issue:11

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Dose Fractionation, Radiati

2003
[A case of liver and lung metastases of rectal cancer responding well to 5-FU hepato-arterial infusion (HAI) with combined use of oral UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sche

2003
[A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administrat

2003
[A case of unresectable liver metastases from rectosigmoid colon cancer with survival for over 3 years after multidisciplinary treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Drug Admini

2003
[A case of locally extended rectal carcinoma quickly responding to local intraarterial infusion therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule;

2003
Preliminary results on the influence of chemoradiation on apparent diffusion coefficients of primary rectal carcinoma measured by magnetic resonance imaging.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2003, Volume: 179, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Catheterization, Central Venous; Combi

2003
Carcinoembryonic antigen surge in metastatic colorectal cancer patients responding to oxaliplatin combination chemotherapy: implications for tumor marker monitoring and guidelines.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Dec-01, Volume: 21, Issue:23

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoembryonic

2003
Rectal adenocarcinoma with germ-cell differentiation: report of a case.
    Diseases of the colon and rectum, 2003, Volume: 46, Issue:12

    Topics: Adenocarcinoma; Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin

2003
Presentations from the Walter Reed Army Medical Center. Case 1: rectal carcinoma.
    Oncology (Williston Park, N.Y.), 2003, Volume: 17, Issue:11

    Topics: Adenocarcinoma, Mucinous; Adult; Camptothecin; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; N

2003
Accuracy of endoscopic ultrasound for restaging rectal cancer following neoadjuvant chemoradiation therapy.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Diagnostic Errors; Dose Fractionati

2004
Biweekly irinotecan plus bolus 5-fluorouracil and folinic acid in patients with advanced stage colorectal cancer.
    Japanese journal of clinical oncology, 2003, Volume: 33, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic N

2003
[Principles of postoperative therapy in rectal carcinoma].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2004, Volume: 75, Issue:1

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agen

2004
[A case of rectal cancer with distant lymph node metastases completely responding to postoperative chemotherapy with levofolinate combined with 5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female

2004
18F-FDG positron emission tomography staging and restaging in rectal cancer treated with preoperative chemoradiation.
    International journal of radiation oncology, biology, physics, 2004, Feb-01, Volume: 58, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorodeoxyglucos

2004
[Preoperative radiation with chemotherapy for rectal cancer: its impact on downstaging of disease and the role of endorectal ultrasound].
    Medicina (Kaunas, Lithuania), 2004, Volume: 40, Issue:1

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma in Situ; Chemotherapy, Adjuvant;

2004
Impact of body mass index on outcomes and treatment-related toxicity in patients with stage II and III rectal cancer: findings from Intergroup Trial 0114.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Feb-15, Volume: 22, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Chemotherapy

2004
Extracapsular spread of nodal metastasis as a prognostic factor in rectal cancer.
    International journal of radiation oncology, biology, physics, 2004, Mar-01, Volume: 58, Issue:3

    Topics: Actuarial Analysis; Adult; Aged; Analysis of Variance; Antimetabolites, Antineoplastic; Combined Mod

2004
Rate of pathologic complete response with increased interval between preoperative combined modality therapy and rectal cancer resection.
    Diseases of the colon and rectum, 2004, Volume: 47, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Combined Modality Thera

2004
Outcome of rectal and sigmoid carcinoma patients receiving adjuvant chemoradiotherapy in Marmara University Hospital.
    Journal of chemotherapy (Florence, Italy), 2003, Volume: 15, Issue:6

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Colectomy; Combined Modality Therap

2003
Changes in apoptotic and mitotic index, bcl2, and p53 expression in rectum carcinomas after short-term cytostatic treatment.
    Annals of the New York Academy of Sciences, 2003, Volume: 1010

    Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Apoptosis; Biopsy; Female; Fluorouracil; Genes

2003
[Analysis of microsatellite instability and p53 LOH in advanced colorectal cancers--first report of the No. 3 protocol].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Admi

2004
[Colorectal cancer: what should be the management of primary tumour?].
    La Revue du praticien, 2004, Jan-31, Volume: 54, Issue:2

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colon; Colonoscopy; Colorectal Neoplasms; D

2004
[Case report of two colorectal cancer patients with liver metastasis showing favorable response to fluorouracil and l-leucovorin therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:4

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule;

2004
Sphincter preservation in locally advanced rectal cancer due to the addition of continuous infusion 5-FU to preoperative radiation therapy or advances in surgical techniques?
    International journal of radiation oncology, biology, physics, 2004, Jun-01, Volume: 59, Issue:2

    Topics: Anal Canal; Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorouracil; Humans; Lymph

2004
Hypersensitivity reactions to oxaliplatin: a case report and the success of a continuous infusional desensitization schedule.
    Anti-cancer drugs, 2004, Volume: 15, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Desen

2004
Substitution of oral fluoropyrimidines for infusional fluorouracil with radiotherapy: how much data do we need?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Aug-01, Volume: 22, Issue:15

    Topics: Administration, Oral; Aminoacridines; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemo

2004
Sequential preoperative fluorodeoxyglucose-positron emission tomography assessment of response to preoperative chemoradiation: a means for determining longterm outcomes of rectal cancer.
    Journal of the American College of Surgeons, 2004, Volume: 199, Issue:1

    Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Colectomy; Fluorodeoxyglucose F18; Fluorouracil; Huma

2004
[Choice of chemotherapeutic drugs for colorectal cancers by DPD and OPRT activities in cancer tissues].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:7

    Topics: Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Dihydrouracil Dehydrogenase (NADP); Female

2004
Anti-metastatic effect of capecitabine on human colon cancer xenografts in nude mouse rectum.
    International journal of cancer, 2004, Oct-20, Volume: 112, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Colonic Neoplasms; Deoxycytidine; Fluorourac

2004
[Long-term control of rectal liver metastases by hepatic arterial infusion chemotherapy of 5-fluorouracil and l-leucovorin--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dru

2004
[Effecting observation of 3-dimensional conformal radiotherapy combined with chemotherapy for rectal cancer of postoperative local recurrence].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2004, Aug-07, Volume: 42, Issue:15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; F

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Chemoradiotherapy for rectal cancer--when, why, and how?
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Antineoplastic Agents; Combined Modality Therapy; Fluorouracil; Humans; Neoplasm Recurrence, Local;

2004
[Relationship between expression of thymidylate synthase and colorectal carcinoma].
    Zhonghua yi xue za zhi, 2004, Sep-02, Volume: 84, Issue:17

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Administration Schedule; Femal

2004
[A case of rectal cancer with multiple liver and peritoneal metastases that responded dramatically to low-dose 5-FU plus LV and CDDP combination chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy

2004
Long-term results using local excision after preoperative chemoradiation among selected T3 rectal cancer patients.
    International journal of radiation oncology, biology, physics, 2004, Nov-15, Volume: 60, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality T

2004
Expression of p27 in residual rectal cancer after preoperative chemoradiation predicts long-term outcome.
    Annals of surgical oncology, 2004, Volume: 11, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap

2004
Thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase expression, and histological tumour regression after 5-FU-based neo-adjuvant chemoradiotherapy in rectal cancer.
    The Journal of pathology, 2004, Volume: 204, Issue:5

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Combined Modality Therapy; D

2004
[Successful treatment of liver metastasis and extrahepatic metastasis with hepatic arterial infusion of CDDP, CPT-11, and 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemothe

2004
[A case of postoperative pelvic metastasis and multiple liver metastases of the rectal cancer successfully treated by arterial infusion therapy with 5-FU/leucovorin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Hepatic Artery; Humans; Iliac Artery;

2004
[A case of long-term survival after chemo-radiation for postoperative local recurrence of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy

2004
[Evaluation of intra-arterial infusion chemotherapy associated with radiotherapy for two cases of local recurrence of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Female;

2004
[Relationship between dihydropyrimidine dehydrogenase(DPD) activity and toxicity of 5-FU-based adjuvant chemotherapy in colorectal cancer patients].
    Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:11 Suppl

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplas

2004
Immunohistochemical evaluation of thymidylate synthase (TS) and p16INK4a in advanced colorectal cancer: implication of TS expression in 5-FU-based adjuvant chemotherapy.
    Japanese journal of clinical oncology, 2004, Volume: 34, Issue:10

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; C

2004
Cardiotoxicity and neurotoxicity of high-dose continuous fluorouracil as a result of degradation compounds in the drug vials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Dec-15, Volume: 22, Issue:24

    Topics: Acetaldehyde; Aged; Antimetabolites, Antineoplastic; Brain Diseases; Carcinoma; Chemistry, Pharmaceu

2004
Complete pathologic response following preoperative chemoradiation therapy for middle to lower rectal cancer is not a prognostic factor for a better outcome.
    Diseases of the colon and rectum, 2004, Volume: 47, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chi-Square

2004
Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2005, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorouracil; Humans;

2005
Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2005, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorouracil; Humans;

2005
Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2005, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorouracil; Humans;

2005
Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2005, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorouracil; Humans;

2005
Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2005, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorouracil; Humans;

2005
Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2005, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorouracil; Humans;

2005
Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2005, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorouracil; Humans;

2005
Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2005, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorouracil; Humans;

2005
Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2005, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorouracil; Humans;

2005
Preoperative chemoradiotherapy and total mesorectal excision surgery for locally advanced rectal cancer: correlation with rectal cancer regression grade.
    Diseases of the colon and rectum, 2004, Volume: 47, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv

2004
[A case of advanced rectal cancer responding to 5-fluorouracil based preoperative chemoradiation therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:1

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Drug Administratio

2005
Update on design of the National Surgical Adjuvant Breast and Bowel Project trial R-04.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Feb-01, Volume: 23, Issue:4

    Topics: Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Fluorouracil; Humans; Rectal Neoplasm

2005
Epidermal growth factor receptor gene polymorphisms predict pelvic recurrence in patients with rectal cancer treated with chemoradiation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Jan-15, Volume: 11, Issue:2 Pt 1

    Topics: Adult; Aged; Antineoplastic Agents; Caenorhabditis elegans Proteins; Chemotherapy, Adjuvant; DNA, Ne

2005
[Present treatment strategies for rectal carcinoma].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2005, Volume: 76, Issue:3

    Topics: Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Endosonography; Fluorourac

2005
[Pharmacokinetic modulating chemotherapy for rectal carcinoma metastases to the liver and lung--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:2

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dru

2005
Australian experience of a modified schedule of FOLFOX with high activity and tolerability and improved convenience in untreated metastatic colorectal cancer patients.
    British journal of cancer, 2005, Mar-14, Volume: 92, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Chemotherapy, Adjuvant; Colo

2005
Lymph node micrometastasis in stage II distal rectal cancer following neoadjuvant chemoradiation therapy.
    International journal of colorectal disease, 2005, Volume: 20, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2005
Expression level of thymidylate synthase is a good predictor of chemosensitivity to 5-fluorouracil in colorectal cancer.
    Journal of gastroenterology, 2005, Volume: 40, Issue:2

    Topics: Antimetabolites, Antineoplastic; Colonic Neoplasms; Dihydrouracil Dehydrogenase (NADP); Drug Screeni

2005
The effects of capecitabine in Raynaud's disease: a case report.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Capecitabine; Deoxycytidine; Fluorouracil; Follow-Up Studie

2005
[A case of bilateral multiple liver metastases with distant lymph node metastases due to rectal cancer successfully treated with hepatic arterial infusion (HAI) of levofolinate (l-LV)/5-fluorouracil (5-FU) and radiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:3

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dr

2005
Radiofrequency ablation therapy of remnant colorectal liver metastases after a course of hepatic arterial infusion chemotherapy.
    Journal of vascular and interventional radiology : JVIR, 2005, Volume: 16, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Catheter Ablation; Catheters, Indwe

2005
[Relationship of serum level of dihydropyrimidine dehydrogenase and serum concentration of 5-fluorouracil to treatment response and adverse events in colorectal cancer patients].
    Ai zheng = Aizheng = Chinese journal of cancer, 2005, Volume: 24, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Dihydroura

2005
[Minutes of the 23th meeting of the European Society for Therapeutic Radiology and Oncology (ESTRO). Amsterdam, 24-28 October 2004].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2005, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amifostine; Antineoplastic Agents, Hormonal; Antineo

2005
Tumour regression grading in the evaluation of tumour response after different preoperative radiotherapy treatments for rectal carcinoma.
    International journal of colorectal disease, 2005, Volume: 20, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv

2005
Preoperative radio-chemotherapy treatment in locally advanced rectal carcinoma. Results of 8-year follow-up.
    Onkologie, 2005, Volume: 28, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Disease-Free Survival; Dose Fractionat

2005
Prognostic and predictive value of the thymidylate synthase expression in patients with non-metastatic colorectal cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2005, Volume: 31, Issue:8

    Topics: Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Chemotherapy, Adjuvant; Colonic Neoplasms;

2005
Preoperative chemotherapy and radiotherapy for locally advanced rectal cancer.
    ANZ journal of surgery, 2005, Volume: 75, Issue:5

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Midd

2005
Complete pathologic response after chemoradiation for rectal cancer.
    Diseases of the colon and rectum, 2005, Volume: 48, Issue:5

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Hu

2005
Preoperative chemoradiation in rectal cancer: why we need a common language.
    Onkologie, 2005, Volume: 28, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease Progression; Dose F

2005
Outcome after the introduction of a multimodality treatment program for locally advanced rectal cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2005, Volume: 31, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

2005
Leflunomide and peripheral neuropathy: a potential interaction between uracil/tegafur and leflunomide.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:1

    Topics: Administration, Oral; Aged; Arthritis, Rheumatoid; Comorbidity; Disease Progression; Drug Administra

2005
Combined-modality neoadjuvant therapy for rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic;

2005
Association of statin use with a pathologic complete response to neoadjuvant chemoradiation for rectal cancer.
    International journal of radiation oncology, biology, physics, 2005, Aug-01, Volume: 62, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspir

2005
Rectal cancer clinical practice guidelines in oncology.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2005, Volume: 3, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Fluorouracil; Humans; Leucovorin; Live

2005
[Retrospective analysis on efficacy and toxicity of 5-fluorouracil (5-FU) and l-leucovorin (l-LV) in advanced or recurrent colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Drug Admin

2005
[Second-line chemotherapy with bi-weekly CPT-11 and cisplatin for recurrent colorectal cancer resistant to 5-FU based chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:7

    Topics: Adult; Aged; Alopecia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cispl

2005
Capecitabine as third line therapy in patients with advanced colorectal cancer.
    Acta oncologica (Stockholm, Sweden), 2005, Volume: 44, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogen

2005
Technique and long-term results of intersphincteric resection for low rectal cancer.
    Diseases of the colon and rectum, 2005, Volume: 48, Issue:10

    Topics: Adenocarcinoma; Adenoma, Villous; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols;

2005
Tumor response to neoadjuvant chemoradiation therapy for rectal adenocarcinoma is mediated by p53-dependent and caspase 8-dependent apoptotic pathways.
    Clinical colorectal cancer, 2005, Volume: 5, Issue:2

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Apoptosis; Biomarkers; Caspase 8; Caspases; F

2005
Response to neoadjuvant therapy for rectal cancer: influence on long-term results.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2005, Volume: 7, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Combined Modal

2005
Serpentine supravenous streaks induced by 5-fluorouracil.
    Journal of the American Academy of Dermatology, 2005, Volume: 53, Issue:3

    Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Hyperpigmentation; Inf

2005
The reliability of lymph-node staging in rectal cancer after preoperative chemoradiotherapy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2005, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

2005
Immunohistochemical analysis of thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase in rectal cancer (cUICC II/III): correlation with histopathologic tumor regression after 5-fluorouracil-based long-term neoadjuvant chemorad
    The American journal of surgical pathology, 2005, Volume: 29, Issue:10

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor;

2005
Can histopathologic assessment of circumferential margin after preoperative pelvic chemoradiotherapy for T3-T4 rectal cancer predict for 3-year disease-free survival?
    International journal of radiation oncology, biology, physics, 2005, Nov-01, Volume: 63, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antimetabolites, Antineoplastic; Combined Moda

2005
Preoperative chemoradiation of locally advanced T3 rectal cancer combined with an endorectal boost.
    International journal of radiation oncology, biology, physics, 2006, Feb-01, Volume: 64, Issue:2

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bra

2006
[Expression of mRNA levels of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyltransferase of colorectal cancer--relationships among mRNA levels in association with response to 5-FU based treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dihydrouracil Dehydr

2005
Pre-operative chemo-radiotherapy improves the sphincter preservation rate in patients with rectal cancer located within 3 cm of the anal verge.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2006, Volume: 32, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Capecit

2006
Preoperative chemoradiation for rectal cancer causes prolonged pudendal nerve terminal motor latency.
    Diseases of the colon and rectum, 2006, Volume: 49, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Biopsy; Female; Fluorouracil; Follow-U

2006
[Pseudomembranous colitis after 5-fluorouracil chemotherapy in rectal cancer patient].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2005, Volume: 46, Issue:5

    Topics: Antimetabolites, Antineoplastic; Colon; Colonoscopy; Enterocolitis, Pseudomembranous; Fluorouracil;

2005
[Colorectal carcinoma].
    Praxis, 2005, Nov-02, Volume: 94, Issue:44

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy

2005
[Five cases of locally advanced rectal cancer or local recurrence performed intra-arterial infusion chemotherapy via the internal iliac artery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Iliac Artery; Infusion

2005
Cyclooxygenase-2 (COX-2) levels before and after chemotherapy: a study in rectal cancer.
    American journal of clinical oncology, 2005, Volume: 28, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Biopsy; Cohort Studies; Combined Modal

2005
Preoperative sequential short-term radiotherapy plus chemotherapy can induce complete remission in T3N2 rectal cancer.
    Acta oncologica (Stockholm, Sweden), 2005, Volume: 44, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidi

2005
Upregulation of thymidine phosphorylase in rectal cancer tissues by mitomycin C.
    Journal of surgical oncology, 2006, Jan-01, Volume: 93, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Che

2006
Thyroid metastasis from colorectal cancer: role of [18F]-fluoro-2-deoxy-D-glucose positron emission tomography.
    Clinical colorectal cancer, 2005, Volume: 5, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Colect

2005
Oncocytic modifications in rectal adenocarcinomas after radio and chemotherapy.
    Virchows Archiv : an international journal of pathology, 2006, Volume: 448, Issue:4

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Cell Transformation, Neopl

2006
Novel two-step resection for lesions between the middle hepatic vein and vena cava which allows the middle hepatic vein to be preserved.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic

2006
Concurrent oxaliplatin, capecitabine, and radiation therapy in the neoadjuvant therapy of rectal adenocarcinoma: can we get the right dose first?
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase

2006
Can molecular imaging predict response to preoperative chemoradiation in patients with rectal cancer? A Fox Chase Cancer Center prospective experience.
    Seminars in oncology, 2005, Volume: 32, Issue:6 Suppl 9

    Topics: Adenocarcinoma; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deoxycytidine; Femal

2005
Weekly oxaliplatin and preoperative radiotherapy as a new neoadjuvant therapy for locally-advanced rectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Sched

2006
Prognostic factors for disease-free survival in patients with T3-4 or N+ rectal cancer treated with preoperative chemoradiation therapy, surgery, and intraoperative irradiation.
    International journal of radiation oncology, biology, physics, 2006, Mar-15, Volume: 64, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

2006
[A case of advanced rectal cancer responding to l-Leucovorin (LV)/5-fluorouracil( 5-FU) therapy as neoadjuvant chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Adminis

2006
Serum CEA as a predictor for the response to preoperative chemoradiation in rectal cancer.
    Journal of surgical oncology, 2006, Feb-01, Volume: 93, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biom

2006
Neoadjuvant radiochemotherapy for patients with locally advanced rectal cancer leads to impairment of the anal sphincter.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Antineoplastic Agents;

2006
Long-term results after neoadjuvant radiochemotherapy for locally advanced resectable extraperitoneal rectal cancer.
    Diseases of the colon and rectum, 2006, Volume: 49, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil

2006
Rectal adenocarcinoma with oncocytic features: possible relationship with preoperative chemoradiotherapy.
    Journal of clinical pathology, 2006, Volume: 59, Issue:10

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Chemotherapy, Adjuvant; Fe

2006
Capecitabine as an alternative in a case of fluorouracil-induced photodermatitis.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2006, Volume: 18, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Ph

2006
Bevacizumab in metastatic colorectal cancer: a left intracardiac thrombotic event.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:7

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2006
Feasibility of 5-Fluorouracil resumption in a patient experiencing drug-induced acute Prinzmetal angina.
    Acta oncologica (Stockholm, Sweden), 2006, Volume: 45, Issue:2

    Topics: Adenocarcinoma; Angina Pectoris, Variant; Electrocardiography; Fluorouracil; Humans; Male; Middle Ag

2006
Capecitabine chemoradiation for rectal cancer after curative surgery.
    Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:1

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Co

2006
Anemia and long-term outcome in adjuvant and neoadjuvant radiochemotherapy of stage II and III rectal adenocarcinoma: the Freiburg experience (1989-2002).
    World journal of gastroenterology, 2006, Mar-28, Volume: 12, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protoco

2006
Effects of radiotherapy on different histopathological types of rectal carcinoma.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2006, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouraci

2006
Multiple periungual pyogenic granulomas following systemic 5-fluorouracil.
    The Australasian journal of dermatology, 2006, Volume: 47, Issue:2

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Diagnosis, Differential; Fluorouracil; Granul

2006
Tumour regression and mesorectal lymph node changes after intensified neoadjuvant chemoradiation for carcinoma of the rectum.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2006, Volume: 114, Issue:3

    Topics: Adenocarcinoma; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Ca

2006
Intraventricular metastases from rectal-sigmoid adenocarcinoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cardiac Tamponad

2006
Poloxamer 188 and propylene glycol-based rectal suppository enhances anticancer effect of 5-fluorouracil in mice.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:5

    Topics: Administration, Rectal; Alanine Transaminase; Animals; Antimetabolites, Antineoplastic; Aspartate Am

2006
Improved incidence of pT0 downstaged surgical specimens in locally advanced rectal cancer (LARC) treated with induction oxaliplatin plus 5-fluorouracil and preoperative chemoradiation.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

2006
[Treatment efficacy of surgical management for liver metastasis from colorectal cancer--a report of 198 cases].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplas

2006
MRI identified prognostic features of tumors in distal sigmoid, rectosigmoid, and upper rectum: treatment with radiotherapy and chemotherapy.
    International journal of radiation oncology, biology, physics, 2006, Jun-01, Volume: 65, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

2006
Defunctioning stomas in the treatment of rectal cancer.
    The British journal of surgery, 2006, Volume: 93, Issue:6

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorouracil; Humans; Neoadjuvant Therap

2006
Preoperative chemoradiation in rectal cancer: Retrospective comparison between capecitabine and continuous infusion of 5-fluorouracil.
    Journal of surgical oncology, 2006, Jun-01, Volume: 93, Issue:7

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols

2006
Neoadjuvant radiochemotherapy in the treatment of fixed and semi-fixed rectal tumors. Analysis of results and prognostic factors.
    Radiation oncology (London, England), 2006, Mar-28, Volume: 1

    Topics: Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil;

2006
Clinical and pathologic predictors of locoregional recurrence, distant metastasis, and overall survival in patients treated with chemoradiation and mesorectal excision for rectal cancer.
    American journal of clinical oncology, 2006, Volume: 29, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant

2006
Postoperative chemotherapy may not be necessary for patients with ypN0-category after neoadjuvant chemoradiotherapy of rectal cancer.
    Diseases of the colon and rectum, 2006, Volume: 49, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modali

2006
[Second-line chemotherapy with pharmacokinetic modulating chemotherapy for unresectable colorectal carcinoma recurrences resistant to 5-FU-based chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chronotherapy; Co

2006
Chemotherapy with bevacizumab, irinotecan, 5-fluorouracil and leucovorin (IFL) associated with a large, embolizing thrombus in the thoracic aorta.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:12

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2006
Quality of Life assessment through the EORTC questionnaires of locally advanced rectal cancer patients treated with preoperative chemo-radiotherapy.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Body Image; Emotions

2006
[The lethal effect of combined MDR1 antisense RNA with oxaliplatin and 5-FU on drug-resistant rectal carcinoma cells].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2006, Jun-01, Volume: 44, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Combined Modality Therapy; Drug Syne

2006
Epidermal growth factor receptor as a predictor of tumor downstaging in locally advanced rectal cancer patients treated with preoperative chemoradiotherapy.
    International journal of radiation oncology, biology, physics, 2006, Sep-01, Volume: 66, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Capecitabine; Combined Modality The

2006
Gene expression in tumor-adjacent normal tissue is associated with recurrence in patients with rectal cancer treated with adjuvant chemoradiation.
    Pharmacogenetics and genomics, 2006, Volume: 16, Issue:8

    Topics: Adult; Aged; Chemotherapy, Adjuvant; Cross-Sectional Studies; Female; Fluorouracil; Gene Expression

2006
A pathologic complete response of rectal cancer to preoperative combined-modality therapy results in improved oncological outcome compared with those who achieve no downstaging on the basis of preoperative endorectal ultrasonography.
    Annals of surgical oncology, 2006, Volume: 13, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality T

2006
Tegafur and 5-fluorouracil pelvic tissue concentrations in rectal cancer patients receiving preoperative chemoradiation.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:7

    Topics: Adipose Tissue; Adult; Aged; Antimetabolites, Antineoplastic; Female; Fluorouracil; Humans; Intestin

2006
Acute small bowel toxicity and preoperative chemoradiotherapy for rectal cancer: investigating dose-volume relationships and role for inverse planning.
    International journal of radiation oncology, biology, physics, 2006, Oct-01, Volume: 66, Issue:2

    Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Diarrhea; Fe

2006
Analysis of clinical outcomes and prognostic factors of neoadjuvant chemoradiotherapy combined with surgery: intraperitoneal versus extraperitoneal rectal cancer.
    European journal of cancer care, 2006, Volume: 15, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Fema

2006
Prognostic value of histologic tumor regression, thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase in rectal cancer UICC Stage II/III after neoadjuvant chemoradiotherapy.
    The American journal of surgical pathology, 2006, Volume: 30, Issue:9

    Topics: Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NADP); Disease-Free Survival; Female;

2006
Prognostic markers of local relapse in rectal cancer: are we any further forward?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Sep-01, Volume: 24, Issue:25

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemotherapy, Adjuvant; Disease-F

2006
Lymph node status and TS gene expression are prognostic markers in stage II/III rectal cancer after neoadjuvant fluorouracil-based chemoradiotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Sep-01, Volume: 24, Issue:25

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemotherapy, Adjuva

2006
Just how useful an endpoint is complete pathological response after neoadjuvant chemoradiation in rectal cancer?
    International journal of radiation oncology, biology, physics, 2006, Oct-01, Volume: 66, Issue:2

    Topics: Antimetabolites, Antineoplastic; Endpoint Determination; Fluorouracil; Humans; Neoadjuvant Therapy;

2006
[Evaluation of weekly low-dose CPT-11 combined with 5-FU/l-LV therapy for advanced and recurrent colorectal cancer--preliminary study].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Col

2006
[A case of advanced rectal carcinoma, preoperative chemo-radiation therapy leading to histological complete response].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colostomy; Combined Modality Therapy; Dru

2006
Neoplastic mesorectal microfoci (MMF) following neoadjuvant chemoradiotherapy: clinical and prognostic implications.
    Annals of surgical oncology, 2006, Volume: 13, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; F

2006
Acute proctocolitis with commencement of neoadjuvant chemoradiation for rectal cancer.
    American journal of clinical oncology, 2006, Volume: 29, Issue:5

    Topics: Acute Disease; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Dose Fractionation, Radiation;

2006
Hand-foot syndrome variant in a dihydropyrimidine dehydrogenase-deficient patient treated with capecitabine.
    Clinical colorectal cancer, 2006, Volume: 6, Issue:3

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deficiency Diseases; Deoxycyt

2006
[Effectiveness of preoperative chemoradiotherapy for advanced rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Drug Admini

2006
[A case of effective multidisciplinary treatment with hepatic resection for synchronous multiple liver metastases from rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubic

2006
[Case report of a liver metastasis from rectal cancer achieving complete response (CR) by a combination of intra-hepatic arterial infusion of irinotecan (CPT-11) with degradable starch microspheres (DSM) and weekly high-dose intra-hepatic arterial chemoth
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:10

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administrat

2006
Preoperative chemoradiotherapy with capecitabine versus protracted infusion 5-fluorouracil for rectal cancer: a matched-pair analysis.
    International journal of radiation oncology, biology, physics, 2006, Dec-01, Volume: 66, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chi-Square Distributi

2006
Matrix metalloproteinase-9 expression correlated with tumor response in patients with locally advanced rectal cancer undergoing preoperative chemoradiotherapy.
    International journal of radiation oncology, biology, physics, 2007, Jan-01, Volume: 67, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female;

2007
Prognostic significance of circumferential resection margin following total mesorectal excision and adjuvant chemoradiotherapy in patients with rectal cancer.
    Annals of surgical oncology, 2007, Volume: 14, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biop

2007
Prognostic significance of circumferential resection margin following total mesorectal excision and adjuvant chemoradiotherapy in patients with rectal cancer.
    Annals of surgical oncology, 2007, Volume: 14, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biop

2007
Prognostic significance of circumferential resection margin following total mesorectal excision and adjuvant chemoradiotherapy in patients with rectal cancer.
    Annals of surgical oncology, 2007, Volume: 14, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biop

2007
Prognostic significance of circumferential resection margin following total mesorectal excision and adjuvant chemoradiotherapy in patients with rectal cancer.
    Annals of surgical oncology, 2007, Volume: 14, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biop

2007
Comparison of 5-fluorouracil/leucovorin and capecitabine in preoperative chemoradiotherapy for locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2007, Feb-01, Volume: 67, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality The

2007
[A case of advanced rectal carcinoma with multiple lung metastases responding to irinotecan combined with 5-fluorouracil and l-leucovorin (IFL) as neoadjuvant chemotherapy (NAC)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant

2006
Combined surgery and chemoradiation as a treatment for the Buschke-Löwenstein tumour.
    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 2006, Volume: 4, Issue:6

    Topics: Abdominal Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinom

2006
Treatment of rectal cancer.
    The New England journal of medicine, 2006, Dec-07, Volume: 355, Issue:23

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Leu

2006
Treatment of rectal cancer.
    The New England journal of medicine, 2006, Dec-07, Volume: 355, Issue:23

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Guideline A

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Female; Flu

2006
Prognostic groups in 1,676 patients with T3 rectal cancer treated without preoperative radiotherapy.
    Diseases of the colon and rectum, 2007, Volume: 50, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

2007
Optimal time interval between capecitabine intake and radiotherapy in preoperative chemoradiation for locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2007, Mar-15, Volume: 67, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine

2007
[Utility of arterial infusion chemotherapy and radiation therapy for the pelvic local recurrence of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:12

    Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial;

2006
[A case report of successful local control with chemoradiation for unresectable rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; M

2006
Efficient and safe application of a FOLFIRI/bevacizumab combination to a patient with locally advanced rectal cancer and severe chronic renal failure.
    Onkologie, 2007, Volume: 30, Issue:1-2

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2007
Addition of weekly oxaliplatin to standard preoperative chemoradiation for locally advanced rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Feb-10, Volume: 25, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clini

2007
[Feasibility of modified FOLFIRI regimen for patients with refractory advanced or recurrent colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:2

    Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplas

2007
Toxicities and survival among octogenarians and nonagenarians with colorectal cancer treated with chemotherapy or concurrent chemoradiation therapy.
    Clinical colorectal cancer, 2007, Volume: 6, Issue:5

    Topics: Age Factors; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2007
Analysis of early postoperative morbidity among patients with rectal cancer treated with and without neoadjuvant chemoradiotherapy.
    Annals of surgical oncology, 2007, Volume: 14, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Case-Control Studies; Combined Modality Therapy; Female

2007
[A retrospective study of irinotecan plus fluorouracil and l-leucovorin chemotherapy for advanced and metastatic colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasm

2007
Outcomes of hepatic artery infusion therapy for hepatic metastases from colorectal carcinoma after radiological placement of infusion catheters.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2007, Volume: 33, Issue:6

    Topics: Aged; Angiography; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Carcinoembryonic Antigen; Car

2007
Prognostic and predictive factors after surgical treatment for locally recurrent rectal cancer: a single institute experience.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2007, Volume: 33, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; Fluoro

2007
Chemotherapy or no chemotherapy in clear margins after neoadjuvant chemoradiation in locally advanced rectal cancer: CHRONICLE. A randomised phase III trial of control vs. capecitabine plus oxaliplatin.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase III as Topic; C

2007
Effect of time interval between surgery and preoperative chemoradiotherapy with 5-fluorouracil or 5-fluorouracil and oxaliplatin on outcomes in rectal cancer.
    Journal of surgical oncology, 2007, Sep-01, Volume: 96, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Disease-Free Survival; Female

2007
Adjuvant therapy for stage II and III colorectal cancer.
    Seminars in oncology, 2007, Volume: 34, Issue:2 Suppl 1

    Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agent

2007
Adjuvant therapy for stage II and III colorectal cancer.
    Seminars in oncology, 2007, Volume: 34, Issue:2 Suppl 1

    Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agent

2007
Adjuvant therapy for stage II and III colorectal cancer.
    Seminars in oncology, 2007, Volume: 34, Issue:2 Suppl 1

    Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agent

2007
Adjuvant therapy for stage II and III colorectal cancer.
    Seminars in oncology, 2007, Volume: 34, Issue:2 Suppl 1

    Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agent

2007
Adjuvant therapy for stage II and III colorectal cancer.
    Seminars in oncology, 2007, Volume: 34, Issue:2 Suppl 1

    Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agent

2007
Adjuvant therapy for stage II and III colorectal cancer.
    Seminars in oncology, 2007, Volume: 34, Issue:2 Suppl 1

    Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agent

2007
Adjuvant therapy for stage II and III colorectal cancer.
    Seminars in oncology, 2007, Volume: 34, Issue:2 Suppl 1

    Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agent

2007
Adjuvant therapy for stage II and III colorectal cancer.
    Seminars in oncology, 2007, Volume: 34, Issue:2 Suppl 1

    Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agent

2007
Adjuvant therapy for stage II and III colorectal cancer.
    Seminars in oncology, 2007, Volume: 34, Issue:2 Suppl 1

    Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agent

2007
A case of capecitabine-induced coronary microspasm in a patient with rectal cancer.
    World journal of gastroenterology, 2007, Apr-14, Volume: 13, Issue:14

    Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Coronary Vasospasm; Deoxycytidine; Dihydrouraci

2007
[A case report of a patient with advanced rectal cancer who was administered chemotherapy in collaboration with a clinical pathway and visiting nursing care].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 2

    Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Community Health Nurs

2006
Preoperative radiotherapy in elderly patients with rectal cancer.
    Gastroenterologie clinique et biologique, 2007, Volume: 31, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; APACHE; Chi-Square Distributi

2007
Capecitabine-induced headache responding to diltiazem.
    Chemotherapy, 2007, Volume: 53, Issue:4

    Topics: Adult; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diltiazem; Female; Fluorouracil

2007
Phase II study of preoperative irradiation and chemotherapy with capecitabine in patients with locally advanced rectal carcinoma.
    Journal of experimental & clinical cancer research : CR, 2007, Volume: 26, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant;

2007
Six-year stabilisation of a relapsed pelvic mass from rectal cancer after oxaliplatin-containing chemotherapy.
    Journal of cancer research and clinical oncology, 2007, Volume: 133, Issue:10

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans;

2007
Is final TNM staging a predictor for survival in locally advanced rectal cancer after preoperative chemoradiation therapy?
    Annals of surgical oncology, 2007, Volume: 14, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

2007
[A case of advanced colon cancer invading the rectum effectively treated with chemoradiation therapy before surgery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Admi

2007
Images in clinical medicine. Diffuse chemoradiotherapy-related enterocolitis.
    The New England journal of medicine, 2007, Jun-14, Volume: 356, Issue:24

    Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Colon; Combined Modality Therapy

2007
Does preoperative chemo-radiotherapy enhance the expression of vascular endothelial growth factor in patients with rectal cancer?
    Oncology reports, 2007, Volume: 18, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Caco-2 Cells; Cell Line, Tumor; Cell Survival; Combined Modal

2007
Oxaliplatin plus 5-fluorouracil/leucovorin (FOLFOX-4) as salvage chemotherapy in patients with pretreated colorectal cancer.
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Adm

2007
Extensive colonic ischemia following treatment with bevacizumab, fluouracil and CPT-11 in a young patient with advanced adenocarcinoma of the rectum.
    The Israel Medical Association journal : IMAJ, 2007, Volume: 9, Issue:6

    Topics: Adenocarcinoma; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Huma

2007
[Evaluation of preoperative radiotherapy or chemoradiotherapy in sphincter preservation for locally advanced middle-low rectal cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape

2007
Squamous-cell carcinoma of the rectum: a rare but curable tumor.
    Diseases of the colon and rectum, 2007, Volume: 50, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Carcinoma, Squam

2007
Microsatellite instability is frequently observed in rectal cancer and influenced by neoadjuvant chemoradiation.
    International journal of radiation oncology, biology, physics, 2007, Aug-01, Volume: 68, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Agents; Female; Fluorouracil; Humans; Male; Microsatellite Instabilit

2007
Modification of leucovorin dose within a simplified FOLFOX regimen improves tolerability without compromising efficacy.
    Clinical colorectal cancer, 2007, Volume: 6, Issue:8

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dose-Respo

2007
Preoperative radiotherapy and concomitant capecitabine treatment induce thymidylate synthase and thymidine phosphorylase mRNAs in rectal carcinoma.
    Neoplasma, 2007, Volume: 54, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Carcinoembryonic Antigen; Combined Modal

2007
[Laparoscopic ovarian transposition and cryopreservation of ovarian tissue before chemo-radiotherapy for rectal cancer].
    Gynecologie, obstetrique & fertilite, 2007, Volume: 35, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Cryo

2007
Analysis of anal sphincter preservation rate according to tumor level and neoadjuvant chemoradiotherapy in rectal cancer patients.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2008, Volume: 12, Issue:1

    Topics: Adenocarcinoma; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2008
[Efficacy of CPT-11 combined 5-FU/CF (FOLFIRI) regimen on advanced colorectal cancer].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic N

2007
Neoadjuvant chemotherapy enables R0 resection of locally advanced rectal cancer in a patient with a previously irradiated pelvis.
    The British journal of radiology, 2007, Volume: 80, Issue:956

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Trans

2007
Survivin, p53, and Ki-67 as predictors of histopathologic response in locally advanced rectal cancer treated with preoperative chemoradiotherapy.
    International journal of colorectal disease, 2008, Volume: 23, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Digestive Syst

2008
Bevacizumab-associated reversible hypotension.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:10

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C

2007
Mucinous rectal adenocarcinoma can be associated to tumor downstaging after preoperative chemoradiotherapy.
    Diseases of the colon and rectum, 2007, Volume: 50, Issue:10

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemother

2007
Dose-volume relationships between enteritis and irradiated bowel volumes during 5-fluorouracil and oxaliplatin based chemoradiotherapy in locally advanced rectal cancer.
    Acta oncologica (Stockholm, Sweden), 2007, Volume: 46, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Dose Fractionation, Radiation; Dose-R

2007
Daily low-dose/continuous capecitabine combined with neo-adjuvant irradiation reduces VEGF and PDGF-BB levels in rectal carcinoma patients.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:1

    Topics: Antimetabolites, Antineoplastic; Becaplermin; Capecitabine; Carcinoma; Combined Modality Therapy; De

2008
Therapy of colon carcinoma: an oncology perspective. Interview with Piotr M. Czaykowski by Paul C. Adams.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2007, Volume: 21, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2007
Survival after radiofrequency ablation of colorectal liver metastases: 10-year experience.
    Annals of surgery, 2007, Volume: 246, Issue:4

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized;

2007
Long-term outcomes of patients with localized rectal cancer treated with chemoradiation or radiotherapy alone because of medical inoperability or patient refusal.
    Diseases of the colon and rectum, 2007, Volume: 50, Issue:12

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Female; Fluorourac

2007
The dose-volume relationship of small bowel irradiation and acute grade 3 diarrhea during chemoradiotherapy for rectal cancer.
    International journal of radiation oncology, biology, physics, 2008, Feb-01, Volume: 70, Issue:2

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Combined Modality Therapy; Diarrhea; Female; Fluorou

2008
Adjuvant management of rectal cancer: the more we learn, the less we know.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-01, Volume: 25, Issue:28

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Fluorouracil; Humans; Neoadj

2007
Preoperative chemoradiation followed by transanal excision for rectal cancer.
    The Journal of surgical research, 2008, Volume: 148, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality T

2008
[A case of metastatic rectal cancer showing a sustained complete response to chemotherapy with FOLFIRI followed by UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Humans; L

2007
Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:3

    Topics: Acetyltransferases; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Line, Tu

2008
[Efficacy of m-FOLFOX6 therapy for colorectal cancer in elderly patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neopla

2007
[A patient with recurrent rectal cancer in whom pulmonary metastasis disappeared by FOLFOX 4 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Ther

2007
Laparoscopic total mesorectal excision after neoadjuvant chemoradiotherapy.
    Surgical oncology, 2007, Volume: 16 Suppl 1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Dose Fractionation, Radiation; Female; Fluorouracil; F

2007
[Long- term remission survival with a case of rectal carcinoid tumor with metastasis in the soft tissue effectively treated with the combination therapy of irinotecan/5-fluorouracil/levofolinate followed by resection].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Nov-10, Volume: 96, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoid Tumor; Chemotherapy, Adjuvan

2007
Cryptogenic organizing pneumonitis during oxaliplatin chemotherapy for colorectal cancer: case report.
    Chest, 2007, Volume: 132, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Cryptogenic Organizing

2007
[Two cases of advanced low rectal cancer, preoperative chemo-radiation therapy leading to complete histological response].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:13

    Topics: Adenocarcinoma; Adult; Aged; Combined Modality Therapy; Fluorouracil; Humans; Lymph Node Excision; M

2007
Biological predictive factors in rectal cancer treated with preoperative radiotherapy or radiochemotherapy.
    British journal of cancer, 2008, Jan-15, Volume: 98, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; C

2008
[Treatment for locally-advanced rectal cancer].
    Voprosy onkologii, 2007, Volume: 53, Issue:5

    Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Digestive System

2007
Isolated chemotherapeutic perfusion of pelvis as neoadjuvant or palliative therapy for advanced cancer of the rectum.
    Annals of surgical oncology, 2008, Volume: 15, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusio

2008
Preoperative irinotecan/5-FU/leucovorin plus concurrent radiotherapy in rectal cancer.
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; D

2008
cT3N0 rectal cancer: potential overtreatment with preoperative chemoradiotherapy is warranted.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jan-20, Volume: 26, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carb

2008
Oxaliplatin-induced immune mediated thrombocytopenia.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:5

    Topics: Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Plat

2008
[A case of multiple liver metastases from rectal cancer in poor performance status successfully treated with hepatic arterial infusion chemotherapy plus CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Fluorouracil; Human

2007
Chemoradiotherapy for rectal cancer: an updated analysis of factors affecting pathological response.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2008, Volume: 20, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clinical Trials, Phase II as

2008
Capecitabine-related cardiotoxicity: recognition and management.
    The journal of supportive oncology, 2008, Volume: 6, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Colonic Neoplasms; Deo

2008
[It's a good ability to keep all your bases covered].
    Cirugia espanola, 2008, Volume: 83, Issue:2

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorouracil; Humans; Liver Neoplasms; N

2008
Chemoradiotherapy followed by surgery in rectal cancer: improved local control using a moderately high pelvic radiation dose.
    Japanese journal of clinical oncology, 2008, Volume: 38, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Chemotherap

2008
[Treatment of rectal cancer and follow up].
    Revista de gastroenterologia de Mexico, 2007, Volume: 72 Suppl 2

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonoscopy; Endoscopy; Female; Fluorouraci

2007
Predictive value of Ki67 and p53 in locally advanced rectal cancer: correlation with thymidylate synthase and histopathological tumor regression after neoadjuvant 5-FU-based chemoradiotherapy.
    World journal of gastroenterology, 2008, Feb-21, Volume: 14, Issue:7

    Topics: Adenocarcinoma; Female; Fluorouracil; Gene Expression; Humans; Ki-67 Antigen; Male; Middle Aged; Neo

2008
Preoperative chemoradiation with capecitabine in locally advanced rectal cancer.
    The Netherlands journal of medicine, 2008, Volume: 66, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality

2008
Radiochemotherapy in combination with regional hyperthermia in preirradiated patients with recurrent rectal cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2008, Volume: 184, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Confidence I

2008
Sphincter-preserving operations following preoperative chemoradiation: an alternative to abdominoperineal resection for lower rectal cancer?
    World journal of surgery, 2008, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Agents; Colectomy; Female

2008
A case of 5-fluorouracil-induced peripheral neuropathy.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:3

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Electromyography; Female; Fluorouracil; Humans; Low

2008
Administration of oxaliplatin to a pregnant woman with rectal cancer.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease-Free Survival

2009
Chronic myeloid leukemia following the treatment of rectal adenocarcinoma.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; De

2008
[A case of liver metastasis of rectal cancer demonstrating complete response for three years to 5-FU/l-leucovorin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:4

    Topics: Aged; Carcinoembryonic Antigen; Colonoscopy; Fluorouracil; Humans; Immunohistochemistry; Leucovorin;

2008
Pulmonary fibrosis after chemotherapy with oxaliplatin and 5-fluorouracil for colorectal cancer.
    Oncology, 2007, Volume: 73, Issue:3-4

    Topics: Adenocarcinoma; Adrenal Cortex Hormones; Aged; Antineoplastic Combined Chemotherapy Protocols; Fluor

2007
[A case of recurrent rectal cancer with lymphangiosis carcinomatosa successfully treated with modified FOLFOX6 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Leucovorin; Lung Neopl

2008
[A case of advanced rectal cancer responding to neoadjuvant chemotherapy with CPT-11, 5-FU and l-LV after coronary artery bypass graft].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Coronary

2008
Intra-arterial chemotherapy in advanced pelvic tumors.
    Archives of surgery (Chicago, Ill. : 1960), 1967, Volume: 94, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Injections, Int

1967
[Intra-arterial chemotherapy using an implantable infusion pump in liver metastases of colorectal tumors and hepatomas].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1984, Volume: 55, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Colonic Neoplasms; Doxoru

1984
[Current status of chemotherapy of gastric and colorectal cancer].
    Onkologie, 1981, Volume: 4, Issue:2

    Topics: Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Neoplasm Invasivene

1981
Adjuvant and palliative treatment of colorectal cancer with fluorinated pyrimidines. A pharmacological and clinical review.
    Acta chirurgica Scandinavica. Supplementum, 1981, Volume: 504

    Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorine; Fluorouracil; Humans; Liver

1981
Colon-specific antigen-p (CSAp). I. Initial clinical evaluation as a marker for colorectal cancer.
    Cancer, 1982, Sep-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Adenoma; Antigens, Neoplasm; Carcinoembryonic Antigen; Colonic Neoplasms; Epitopes;

1982
Colorectal cancer. Radiotherapy.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1982, Volume: 83

    Topics: Animals; Carcinoembryonic Antigen; Colonic Neoplasms; Dose-Response Relationship, Radiation; Fluorou

1982
Hepatic artery infusion with 5-fluorouracil and mitomycin-C in metastatic colorectal carcinoma phase II study.
    Medical and pediatric oncology, 1982, Volume: 10, Issue:5

    Topics: Adult; Aged; Catheterization; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female;

1982
Elucidation of pathways of 5-fluorouracil metabolism in xenografts of human colorectal adenocarcinoma.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:6

    Topics: Adenocarcinoma; Allopurinol; Animals; Colonic Neoplasms; Female; Fluorouracil; Humans; Hypoxanthines

1983
Ten years' experience with a multimodality treatment of advanced stages of rectal cancer.
    Cancer, 1983, Dec-01, Volume: 52, Issue:11

    Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Re

1983
Palliative therapy of pelvic tumors by intra-arterial infusion of cytotoxic drugs.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 86

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Doxorubicin; Fe

1983
Clinical pharmacological studies of concurrent infusion of 5-fluorouracil and thymidine in treatment of colorectal carcinomas.
    Cancer research, 1982, Volume: 42, Issue:7

    Topics: Colonic Neoplasms; Drug Therapy, Combination; Floxuridine; Fluorouracil; Humans; Infusions, Parenter

1982
[The combination methyl-CCNU, vincristine, 5-fluorouracil and streptozotocin in the treatment of advanced colo-rectal adenocarcinoma].
    Schweizerische medizinische Wochenschrift, 1982, Jun-26, Volume: 112, Issue:26

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Leu

1982
Continuous five-day infusion of PALA and 5FU: a pilot phase II trial.
    Medical and pediatric oncology, 1983, Volume: 11, Issue:3

    Topics: Adult; Aged; Aspartic Acid; Carcinoma; Colonic Neoplasms; Drug Administration Schedule; Drug Eruptio

1983
Prolonged and continuous percutaneous intra-arterial hepatic infusion chemotherapy in advanced metastatic liver adenocarcinoma from colorectal primary.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 86

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality

1983
[Local infusion therapy in liver metastases of colorectal cancers. Results of a phase-II study].
    Deutsche medizinische Wochenschrift (1946), 1984, Apr-06, Volume: 109, Issue:14

    Topics: Catheters, Indwelling; Colonic Neoplasms; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusio

1984
[Cardiotoxicity of 5-fluorouracil].
    La Clinica terapeutica, 1984, Jan-31, Volume: 108, Issue:2

    Topics: Aged; Breast Neoplasms; Dose-Response Relationship, Drug; Electrocardiography; Female; Fluorouracil;

1984
Phase II study of methyl-CCNU, vincristine, 5-fluorouracil, and streptozotocin in advanced colorectal cancer. By the Gastrointestinal Tumor Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Female; Fluorour

1984
[Up-date of the chemotherapy of carcinoma of the colo-rectum: our experience with 5-fluorouracil and folinic acid in high doses].
    La Clinica terapeutica, 1984, Aug-31, Volume: 110, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Leu

1984
[Chemotherapy of gastrointestinal cancer in the advanced stage with a combination of 5-fluorouracil, adriamycin, mitomycin C (FAM). A non-controlled study].
    La Clinica terapeutica, 1984, Aug-31, Volume: 110, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Drug Ev

1984
Prognostic factors and in vitro cytotoxic sensitivity in colorectal cancer.
    The British journal of surgery, 1984, Volume: 71, Issue:12

    Topics: Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Colonic Neoplasms; Floxuridine

1984
[Treatment of rectocolic and gastric adenocarcinomas with 5-fluorouracil associated with high doses of folinic acid. Results of an experimental study].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1982, Sep-16, Volume: 58, Issue:33

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Leu

1982
[Completely implantable infusion pump. A new therapeutic possibility for selected patients with liver tumors].
    Deutsche medizinische Wochenschrift (1946), 1983, Jul-01, Volume: 108, Issue:26

    Topics: Carcinoma, Hepatocellular; Catheters, Indwelling; Colonic Neoplasms; Floxuridine; Fluorouracil; Hepa

1983
Patterns of failure after surgical cure of large liver tumors. A change in the proximate cause of death and a need for effective systemic adjuvant therapy.
    American journal of surgery, 1984, Volume: 147, Issue:4

    Topics: Adult; Aged; Carcinoembryonic Antigen; Carcinoma, Hepatocellular; Colonic Neoplasms; Combined Modali

1984
Sequential methotrexate and 5-fluorouracil: improved response rate in metastatic colorectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Colonic Neoplasms; Drug

1984
Potentiation of the antitumor action of 5-fluorouracil with 5-ethyl-2'-deoxyuridine in human colorectal tumor xenografts.
    Oncology, 1984, Volume: 41, Issue:3

    Topics: Adenocarcinoma, Mucinous; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Coloni

1984
Phase I-II trial of high-dose calcium leucovorin and 5-fluorouracil in advanced colorectal cancer.
    Cancer research, 1984, Volume: 44, Issue:10

    Topics: Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Leucovorin; Male; Mid

1984
Immune capability of rats with colorectal carcinoma treated by resection with or without 5-fluorouracil or levamisole.
    Journal of surgical oncology, 1984, Volume: 27, Issue:3

    Topics: Animals; B-Lymphocytes; Cell Migration Inhibition; Colonic Neoplasms; Cytotoxicity, Immunologic; Flu

1984
[Isolated liver perfusion in advanced metastases of colorectal cancers].
    Onkologie, 1984, Volume: 7, Issue:1

    Topics: Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Fluorouracil; Humans; Liver Neoplasms;

1984
Continuous intravenous administration of 1-(2-tetrahydrofuryl)-5-fluorouracil [FT] by intravenous hyperalimentation (IVH)--stability of FT in IVH solution and tumor levels of 5-fluorouracil (5-FU).
    Japanese journal of clinical oncology, 1983, Volume: 13, Issue:1

    Topics: Colonic Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Humans; Parenteral Nutrition, Tot

1983
Phase II study of ftorafur in previously untreated and treated patients with advanced colorectal cancer.
    Cancer treatment reports, 1983, Volume: 67, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male;

1983
[A study on postoperative long-term continuous immuno-chemotherapy with PSK and 5-FUDS for advanced gastric and colo-rectal cancers].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:3

    Topics: Aged; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Human

1983
[Intra-arterial infusion chemotherapy for metastatic hepatic tumor of colo-rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil

1983
Combination of dacarbazine, mitomycin C, 5-fluorouracil and vincristine in advanced colorectal cancer.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dacarbazine; Female;

1983
[Cooperative phase II study of spansule tegafur (SF-SP)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:2

    Topics: Administration, Oral; Aged; Breast Neoplasms; Capsules; Colonic Neoplasms; Delayed-Action Preparatio

1984
Phase I-II studies of oral tegafur (ftorafur).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:2

    Topics: Administration, Oral; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Dose-Response Relationship,

1983
Treatment of metastatic colorectal carcinoma with 5-FU, mitomycin, vincristine, and methotrexate.
    Cancer treatment reports, 1984, Volume: 68, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Fem

1984
[The case studies on oral administration of tegafur encapsulated with slow releasing granule (SF-SP) for three rectal patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:5

    Topics: Adenocarcinoma; Administration, Oral; Aged; Capsules; Delayed-Action Preparations; Female; Fluoroura

1984
Intra-arterial infusion chemotherapy in rectal cancer.
    Canadian journal of surgery. Journal canadien de chirurgie, 1984, Volume: 27, Issue:1

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Female; Fluoroura

1984
[Experimental chemotherapy of human gastrointestinal and breast cancers in nude mice and its correlation to clinical effect].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:9 Suppl

    Topics: Adenocarcinoma; Adult; Aged; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Pr

1984
[Study on the concentration of FT-207 and 5-FU in serum, lymph nodes and tissues after administration of FT-207 suppositories].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8

    Topics: Adult; Aged; Breast Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Lymphoma, Non-Hodgkin; Mal

1984
[Morphologic, ultrastructural and histochemical changes in rectal cancer after intrarectal fluorouracil therapy].
    Zhonghua yi xue za zhi, 1984, Volume: 64, Issue:9

    Topics: DNA, Neoplasm; Fluorouracil; Histocytochemistry; Humans; Rectal Neoplasms

1984
[Combined treatment data on rectal cancer].
    Voprosy onkologii, 1981, Volume: 27, Issue:8

    Topics: Aged; Fluorouracil; Humans; Kyrgyzstan; Male; Neoplasm Staging; Rectal Neoplasms; Rectum

1981
Studies on surgical adjuvant chemotherapy for colorectal cancer and administration of neocarzinostatin into the lumen of the colon or rectum using a double balloon catheter and iontophoresis.
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1981, Jan-01, Volume: 50, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Catheterization; Colonic Neoplasms; Dogs; Fluorouracil; Humans

1981
Adjuvant therapy for carcinoma of the colon and rectum.
    International advances in surgical oncology, 1984, Volume: 7

    Topics: Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; L

1984
A combination of 5-fluorouracil and thymidine in advanced colorectal carcinoma.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Colonic Neoplasms; Drug Sy

1984
Clinical trial of sequential N-phosphonacetyl-L-aspartate, thymidine, and 5-fluorouracil in advanced colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Ataxia; Colonic Neoplasm

1984
Comparative levels of tissue enzymes concerned in the early metabolism of 5-fluorouracil in normal and malignant human colorectal tissue.
    British journal of cancer, 1984, Volume: 50, Issue:5

    Topics: Aged; Colon; Colonic Neoplasms; Epithelium; Female; Fluorouracil; Humans; Male; Middle Aged; Pentosy

1984
[Adjuvant chemotherapy in cancers of the stomach, pancreas and intestine].
    Bulletin du cancer, 1984, Volume: 71, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined M

1984
Evaluation of a sequential 5-FU and hydroxyurea combination in advanced bowel cancer.
    Cancer treatment reports, 1984, Volume: 68, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonic Neoplasms;

1984
Sequential combination chemotherapy with methotrexate and 5-fluorouracil in advanced colorectal carcinoma.
    Tumori, 1984, Dec-31, Volume: 70, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration

1984
Phase II study of hepatic artery infusion with 5-fluorouracil, adriamycin, and mitomycin C (FAM) in liver metastases from colorectal carcinoma.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Fluorouracil;

1984
[Treatment of advanced colonic and rectal adenocarcinoma: combination of 5-FU and high-dose folinic acid].
    Bulletin du cancer, 1983, Volume: 70, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluo

1983
[Evaluation of intraluminal fluorouracil chemotherapy as an adjuvant to radical resection of colorectal cancers].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1983, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Aged; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans;

1983
Clinical and in vivo response following surgery or surgery plus adjuvant chemotherapy or immunotherapy for colorectal carcinoma in a rat model.
    Journal of the Royal Society of Medicine, 1983, Volume: 76, Issue:10

    Topics: Animals; Colonic Neoplasms; Combined Modality Therapy; Disease Models, Animal; Fluorouracil; Levamis

1983
[A clinical study (phase II) of a combination of 5-fluorouracil, vincristine and methyl CCNU in patients with advanced carcinoma of the large intestine].
    Lijecnicki vjesnik, 1983, Volume: 105, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation;

1983
First histologic findings in metastases of colorectal carcinoma following isolated liver perfusion with cytostatics.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 86

    Topics: Adenocarcinoma; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Fluorouracil; Humans; L

1983
Intra-arterial perfusion therapy with 5-fluorouracil in patients with metastatic colorectal carcinoma and intractable pelvic pain.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 86

    Topics: Adult; Colonic Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Fluor

1983
Transient repeated dearterialization combined with intra-arterial infusion of oncolytic drugs in the treatment of liver tumors.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 86

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Cyclophosphamide; Duod

1983
First experimental and clinical results of isolated liver perfusion with cytotoxics in metastases from colorectal primary.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 86

    Topics: Animals; Antineoplastic Agents; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Colonic N

1983
5-Fluorouracil, vincristine and hydroxyurea combination chemotherapy in metastatic colorectal cancer.
    Tumori, 1983, Oct-31, Volume: 69, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Hyd

1983
[Treatment of advanced cancer of the colon and rectum with the combination of 5-fluorouracil, imidazolecarboxamide and vincristine].
    Medicina, 1983, Volume: 43, Issue:2

    Topics: Aged; Aminoimidazole Carboxamide; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms;

1983
Sequential methotrexate plus 5-FU in advanced breast and colorectal cancers: a phase II study.
    Cancer treatment reports, 1984, Volume: 68, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Drug Evaluation

1984
Chemoradiotherapeutic prevention of local recurrence after stapled anastomoses in rectal cancer.
    Scottish medical journal, 1981, Volume: 26, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Female; Fluorouracil; Follow-Up Studies; Humans;

1981
Comparative efficacy of antitumor treatment for liver metastases from colorectal cancer.
    The Japanese journal of surgery, 1981, Volume: 11, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Hepatic Artery; Humans;

1981
Chemotherapy of carcinomas of the digestive tract.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1982, Volume: 80

    Topics: Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Administration Schedule; Esop

1982
Intrahepatic artery 5-fluorouracil and mitomycin-C in previously untreated patients with hepatic metastases from colorectal carcinoma.
    Military medicine, 1982, Volume: 147, Issue:3

    Topics: Adult; Colonic Neoplasms; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Mitomyci

1982
[Adjuvant treatment in surgery of colon and rectal cancer].
    Acta gastroenterologica Latinoamericana, 1982, Volume: 12, Issue:2

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Immunotherapy; Prognosis; Rectal Neoplasms; Thiotepa

1982
Severe glomerular mesangiolysis in a patient with rectal adenocarcinoma treated with cytotoxic drugs.
    Virchows Archiv. A, Pathological anatomy and histopathology, 1982, Volume: 398, Issue:2

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Cytarabine; Fluorescent Antibody Technique; Fluorouraci

1982
[Clinical trial of UFT in recurrent or advanced cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasm

1982
[Clinical study of serum and tissue concentrations of FT-207 and 5-FU in patients with cancer of the large intestine following preoperative application of FT-207 suppositories].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:9

    Topics: Adult; Aged; Biological Assay; Female; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Large;

1982
[Gastrointestinal tumors: chemotherapeutic preparations].
    Fortschritte der Medizin, 1983, Apr-07, Volume: 101, Issue:13

    Topics: Antineoplastic Agents; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Gast

1983
[Treatment of cancers of the colon and rectum].
    Revue medicale de Bruxelles, 1983, Volume: 4, Issue:3

    Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Rectal Ne

1983
Chemotherapy of chemically-induced colorectal tumours.
    Journal of the Royal Society of Medicine, 1983, Volume: 76, Issue:6

    Topics: Animals; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Female; Fluorouracil; Neopla

1983
Metastatic colorectal cancer. Combination chemotherapy in patients previously treated with 5-fluorouracil.
    New York state journal of medicine, 1980, Volume: 80, Issue:8

    Topics: Adult; Aged; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middl

1980
Rectal adenocarcinoma treated with intra-arterial 5-fluorouracil. Prolonged remission.
    New York state journal of medicine, 1982, Volume: 82, Issue:3

    Topics: Adenocarcinoma; Female; Fluorouracil; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neop

1982
Sequential methotrexate and 5-FU in the treatment of colorectal cancer.
    Cancer treatment reports, 1982, Volume: 66, Issue:7

    Topics: Colonic Neoplasms; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Follow-Up

1982
Treatment of advanced colorectal and gastric adenocarcinomas with 5-FU combined with high-dose folinic acid: a pilot study.
    Cancer treatment reports, 1982, Volume: 66, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Gastrointesti

1982
Preoperative use of 5-fluorouracil suppository for carcinoma of the rectum.
    American journal of surgery, 1982, Volume: 143, Issue:2

    Topics: Adult; Aged; Female; Fluorouracil; Humans; Intestinal Mucosa; Male; Methods; Middle Aged; Preoperati

1982
[Sequential methotrexate and fluorouracil in metastasizing colorectal carcinomas. Results of a phase II pilot study (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1982, Apr-02, Volume: 107, Issue:13

    Topics: Adult; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Life Expectancy; Male; Methotrexate; M

1982
Fluorouracil for colorectal cancer: a sobering look.
    JAMA, 1982, May-28, Volume: 247, Issue:20

    Topics: Colonic Neoplasms; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Rectal Neoplasms

1982
[Immunotherapy in the treatment of colorectal cancers in the aged].
    Minerva medica, 1982, Apr-28, Volume: 73, Issue:18

    Topics: Aged; Aging; BCG Vaccine; Carmustine; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Middle

1982
Phase II study of sequential methotrexate-5-FU therapy in advanced measurable colorectal cancer.
    Cancer treatment reports, 1982, Volume: 66, Issue:7

    Topics: Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Fluorou

1982
[Chemotherapy of colorectal cancer].
    Sovetskaia meditsina, 1982, Issue:4

    Topics: Antineoplastic Agents; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combinatio

1982
Sequential phase II studies of chemotherapy for colorectal cancer with 5-fluorouracil and vindesine with or without methyl-1,3 cis(2 chloroethyl)-1-nitrosourea.
    American journal of clinical oncology, 1982, Volume: 5, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; F

1982
Colorectal cancer. Chemotherapy.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1982, Volume: 83

    Topics: Adjuvants, Pharmaceutic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Colonic Neoplasms;

1982
Colorectal cancer. Prospects in management.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1982, Volume: 83

    Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Colonic Neoplasms; Fluorouracil; Humans; Postoperat

1982
Combination chemotherapy in patients with advanced colorectal carcinoma previously treated with 5-FU.
    Cancer treatment reports, 1982, Volume: 66, Issue:12

    Topics: Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Nitrosourea Compou

1982
Therapy of liver tumors metastatic from colorectal cancer with whole-liver radiation combined with 5-FU, adriamycin, and methotrexate.
    Cancer chemotherapy and pharmacology, 1982, Volume: 9, Issue:1

    Topics: Aged; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver

1982
Clinical trials and the consent of the patient.
    The Practitioner, 1982, Volume: 226, Issue:1373

    Topics: Aged; Clinical Trials as Topic; Ethics Committees, Research; Ethics, Medical; Female; Fluorouracil;

1982
[Results of surgical and complex treatment of colonic and rectal cancer].
    Archiv fur Geschwulstforschung, 1982, Volume: 52, Issue:6

    Topics: Colectomy; Colonic Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Lomustine; Neoplasm Staging; P

1982
[Isolated liver perfusion with 5-fluorouracil (5-FU) in the human].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1982, Volume: 53, Issue:9

    Topics: Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Female; Fluorouracil; Humans; Liver Neo

1982
[Clinical studies on 5-fluorouracil suppository for rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:4

    Topics: Adult; Aged; Female; Fluorouracil; Humans; Male; Middle Aged; Rectal Neoplasms; Rectum; Suppositorie

1982
Treatment of asymptomatic metastatic cancer to the liver from primary colon and rectal cancer by the intraarterial administration of chemotherapy and radioactive isotopes.
    Journal of surgical oncology, 1982, Volume: 20, Issue:3

    Topics: Antineoplastic Agents; Catheters, Indwelling; Cisplatin; Colonic Neoplasms; Drug Therapy, Combinatio

1982
Methyl-CCNU, 6-thioguanine, and 5-fluorouracil in advanced colorectal cancer.
    Medical and pediatric oncology, 1981, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Hum

1981
Chemotherapy of human colorectal tumor xenografts in athymic mice with clinically active drugs: 5-fluorouracil and 1-3-bis-(-2-chloroethyl)-1-nitrosourea (BCNU). Comparison with doxorubicin derivatives: 4'deoxydoxorubicin and 4'-O-methyldoxorubicin.
    International journal of cancer, 1981, Jan-15, Volume: 27, Issue:1

    Topics: Adenocarcinoma; Animals; Carmustine; Colonic Neoplasms; Doxorubicin; Fluorouracil; Humans; Mice; Mic

1981
[Analysis of radiobiological parameters of radiation therapy of local rectum carcinomas after preceding synchronization of the tumour cell cycle (author's transl)].
    Radiobiologia, radiotherapia, 1981, Volume: 22, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Cell Cycle; Fluorouracil; Humans; Middle Aged; Rectal Neoplasms

1981
Therapy for metastatic colorectal carcinoma with a combination of methyl-CCNU, 5-fluorouracil vincristine and streptozotocin (MOF-Strep).
    Cancer, 1980, Mar-01, Volume: 45, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorourac

1980
[Treatment of inoperable liver metastases: preliminary results with intrahepatic chemotherapy via a new type of indwelling catheter (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, Aug-28, Volume: 106, Issue:35

    Topics: Adult; Aged; Catheters, Indwelling; Colonic Neoplasms; Female; Fluorouracil; Hepatic Artery; Humans;

1981
Studies in an animal model on the effectiveness of adjuvant chemotherapy with 5-FU and BCNU in cases of colorectal adenocarcinoma.
    Journal of cancer research and clinical oncology, 1981, Volume: 100, Issue:2

    Topics: Adenocarcinoma; Animals; Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluoroura

1981
Inoperable rectal cancer.
    The Journal of family practice, 1981, Volume: 13, Issue:3

    Topics: Activities of Daily Living; Aged; Female; Fluorouracil; Home Care Services; Home Nursing; Humans; Re

1981
[Intra-arterial injection of antineoplastic agents in colorectal neoplasms].
    Nihon rinsho. Japanese journal of clinical medicine, 1981, Volume: 39, Issue:5

    Topics: Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Humans; Injections, Intra-Arterial; Mitomyci

1981
Long-term survivors with nonresectable advanced carcinoma of the rectum.
    Diseases of the colon and rectum, 1981, Volume: 24, Issue:7

    Topics: Adenocarcinoma; Aged; Female; Fluorouracil; Follow-Up Studies; Humans; Middle Aged; Prognosis; Recta

1981
Transfemoral hepatic artery infusion for metastatic carcinoma.
    Journal of surgical oncology, 1981, Volume: 18, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Doxorubicin; Female; Femoral Artery; Fluorour

1981
Phase I study of protracted venous infusion of 5-fluorouracil.
    Cancer, 1981, Dec-15, Volume: 48, Issue:12

    Topics: Adult; Aged; Catheters, Indwelling; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Admini

1981
Response of metastatic cloacogenic carcinoma to treatment with semustine.
    Cancer, 1981, Dec-15, Volume: 48, Issue:12

    Topics: Anus Neoplasms; Carcinoma, Transitional Cell; Drug Administration Schedule; Female; Fluorouracil; Hu

1981
[Gastrointestinal tumors. Prognostic factors and chemotherapy of today].
    Deutsche medizinische Wochenschrift (1946), 1981, Dec-04, Volume: 106, Issue:49

    Topics: Carmustine; Colonic Neoplasms; Doxorubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans

1981
[Current aspects of precautional therapy of colorectal neoplasms].
    Minerva medica, 1980, Mar-17, Volume: 71, Issue:10

    Topics: Antineoplastic Agents; BCG Vaccine; Colonic Neoplasms; Fluorouracil; Humans; Immunotherapy; Postoper

1980
The value of lymphocyte transformation in carcinoma of the colon and rectum.
    Surgery, gynecology & obstetrics, 1980, Volume: 150, Issue:5

    Topics: Adenocarcinoma; Carcinoembryonic Antigen; Colonic Neoplasms; Fluorouracil; Humans; Lymphocyte Activa

1980
Adjuvant chemotherapy of human colorectal adenocarcinoma after growth on mice with congenital thymic dysplasia ("nude"). 2. Tumor remission following treatment with 5-FU and VCR of xenotransplanted primary human colorectal adenocarcinomas.
    Journal of cancer research and clinical oncology, 1980, Volume: 97, Issue:1

    Topics: Adenocarcinoma; Animals; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Mice; Mice,

1980
Treatment of carcinoma of the rectum and squamous carcinoma of the anus by combination chemotherapy, radiotherapy and operation.
    Surgery, gynecology & obstetrics, 1980, Volume: 151, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans;

1980
Chemotherapy for gastrointestinal malignancy.
    The American journal of gastroenterology, 1980, Volume: 74, Issue:1

    Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Therapy, Combination; Esophageal Neoplasms; Fluoroura

1980
Comparison of two combination chemotherapy regimens in advanced colorectal cancer.
    British medical journal, 1980, Aug-30, Volume: 281, Issue:6240

    Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorourac

1980
[Adjuvant chemotherapy of human colorectal adenocarcinoma after growth on mice with congenital thymic dysplasia ("nude"). 1. Experiments to test the feasibility of combined chemotherapy with VCR and 5-FU (author's transl)].
    Journal of cancer research and clinical oncology, 1980, Volume: 96, Issue:3

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Mice; M

1980
Clinical studies of intrarectal administration of 5-FU emulsion as an adjunct to surgical treatment of rectal cancer.
    The Japanese journal of surgery, 1980, Volume: 10, Issue:2

    Topics: Emulsions; Fluorouracil; Humans; Lymphatic Metastasis; Preoperative Care; Rectal Neoplasms; Rectum;

1980
Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice.
    Cancer research, 1981, Volume: 41, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Fluorodeoxyuridylate; Fluorouracil; Humans; M

1981
[Clinical and morphological determination of the effectiveness of preoperative radiologic and combined radiologic-chemotherapeutic therapy in locally metastasized rectal cancer].
    Radiobiologia, radiotherapia, 1980, Volume: 21, Issue:4

    Topics: Adult; Aged; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Preoperative Care

1980
Modulation of 5-fluorouracil metabolism and cytotoxicity by antimetabolite pretreatment in human colorectal adenocarcinoma HCT-8.
    Cancer research, 1981, Volume: 41, Issue:3

    Topics: Adenocarcinoma; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Fluorouracil; Humans; Me

1981
Preoperative chemoradiation downstages locally advanced ultrasound-staged rectal cancer.
    American journal of surgery, 1995, Volume: 170, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middl

1995
5-Fluorouracil/levamisole induced intrahepatic fat infiltration imitating liver metastasis.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:7

    Topics: Adult; Antineoplastic Agents; Chemotherapy, Adjuvant; Diagnosis, Differential; Fatty Liver; Fluorour

1995
The style of early clinical research reporting: what are we saying and how do we say it?
    Journal of cancer education : the official journal of the American Association for Cancer Education, 1993,Winter, Volume: 8, Issue:4

    Topics: Abstracting and Indexing; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Car

1993
Preoperative infusional chemoradiation therapy for stage T3 rectal cancer.
    International journal of radiation oncology, biology, physics, 1995, Jul-15, Volume: 32, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Drug Administration Sched

1995
Isolated pelvic perfusion for unresectable cancer using a balloon occlusion technique.
    Archives of surgery (Chicago, Ill. : 1960), 1993, Volume: 128, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcino

1993
[Adjuvant therapy after curative resection of rectal carcinoma].
    Deutsche medizinische Wochenschrift (1946), 1995, Apr-13, Volume: 120, Issue:15

    Topics: Chemotherapy, Adjuvant; Disease-Free Survival; Fluorouracil; Humans; Radiotherapy, Adjuvant; Rectal

1995
Cardiotoxicity related to 5-fluorouracil chemotherapy: a report of two cases.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1995, Volume: 55, Issue:3

    Topics: Aged; Female; Fluorouracil; Humans; Male; Middle Aged; Myocardial Infarction; Nasopharyngeal Neoplas

1995
Interaction of 5-fluorouracil with folates.
    Australian and New Zealand journal of medicine, 1995, Volume: 25, Issue:1

    Topics: Aged; Colonic Neoplasms; Drug Interactions; Drug Therapy, Combination; Female; Fluorouracil; Folic A

1995
[Low-dose continuous infusion therapy 5-FU and CDDP enabled terminal patients with lung and rectal cancer to remain at home].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 4

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorourac

1994
[The immediate results of the combined treatment of rectal cancer using intra-arterial selective polychemotherapy].
    Klinicheskaia khirurgiia, 1994, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Doxorubicin; Female; Fluorou

1994
Colo-rectal carcinoma in a tropical African population: an overview report.
    East African medical journal, 1994, Volume: 71, Issue:10

    Topics: Adenocarcinoma; Administration, Rectal; Adolescent; Adult; Aged; Anus Neoplasms; Ascites; Colonic Ne

1994
Adjuvant treatment for cancer of the colon and rectum.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1994, Volume: 6, Issue:5

    Topics: Chemotherapy, Adjuvant; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Rectal N

1994
[Endolymphatic polychemotherapy with local ultra high frequency hyperthermia for the combined treatment of invasive rectal cancer].
    Klinicheskaia khirurgiia, 1993, Issue:5

    Topics: Adenosarcoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy;

1993
Treatment of patients with irresectable liver metastases from colorectal cancer by chemo-occlusion with degradable starch microspheres.
    The British journal of surgery, 1994, Volume: 81, Issue:9

    Topics: Adult; Aged; Chemoembolization, Therapeutic; Colonic Neoplasms; Female; Fluorouracil; Humans; Liver

1994
[A case report of rectal cancer with lymph node metastasis effectively treated by neoadjuvant chemotherapy of 5-FU oral and low-dose CDDP transarterial administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:15

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cispla

1994
Treatment of advanced colorectal cancer with folinic acid and 5-fluorouracil in combination with cisplatinum.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Female; Fluorour

1994
[Therapy of anal cancer].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1994, Volume: 65, Issue:4

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therap

1994
Necrosis in a meningioma following systemic chemotherapy. Case report.
    Journal of neurosurgery, 1994, Volume: 81, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Embolizat

1994
[Radiotherapy versus radiotherapy plus 5-FU in inoperable or recurrent rectal cancer].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1994, Volume: 170, Issue:4

    Topics: Combined Modality Therapy; Fluorouracil; Humans; Neoplasm Recurrence, Local; Rectal Neoplasms

1994
Local excision of rectal carcinoma. Early results with combined chemoradiation therapy using 5-fluorouracil and leucovorin.
    Diseases of the colon and rectum, 1994, Volume: 37, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

1994
Laparoscopic intestinal stomas.
    Diseases of the colon and rectum, 1994, Volume: 37, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Colonic Diseases; Colostomy;

1994
[Reservoir system implantation technique via the inferior epigastric artery for local recurrence of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:13

    Topics: Aged; Cisplatin; Embolization, Therapeutic; Evaluation Studies as Topic; Female; Fluorouracil; Human

1993
Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy.
    Cancer research, 1993, Nov-15, Volume: 53, Issue:22

    Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Dihydrouracil Dehydrogenase (NADP); Female; Fluoro

1993
[Protracted infusion versus bolus administration of 5-FU in adjuvant radiochemotherapy of rectal cancer].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1994, Volume: 170, Issue:1

    Topics: Chemotherapy, Adjuvant; Combined Modality Therapy; Fluorouracil; Humans; Rectal Neoplasms

1994
Concomitant preoperative radiochemotherapy in operable locally advanced rectal cancer.
    Diseases of the colon and rectum, 1994, Volume: 37, Issue:2 Suppl

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluoroura

1994
Preoperative irradiation and fluorouracil chemotherapy for locally advanced rectosigmoid carcinoma: phase I-II study.
    Radiology, 1993, Volume: 188, Issue:2

    Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Gastrointestinal Diseases; Humans; Mal

1993
Carboplatin in patients with advanced colorectal cancer pretreated with fluoropyrimidines.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Carboplatin; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Mid

1993
Bowel rest, intravenous hydration, and continuous high-dose infusion of octreotide acetate for the treatment of chemotherapy-induced diarrhea in patients with colorectal carcinoma.
    Cancer, 1993, Sep-01, Volume: 72, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diar

1993
[Clinical application of drug delivery system of anti-cancer drugs--the pharmacokinetics and clinical results].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:12

    Topics: Antibodies, Monoclonal; Drug Delivery Systems; Fluorouracil; Humans; Immunotoxins; Iodized Oil; Mito

1993
[Metachronous liver metastases treated with repeated liver resections and chemotherapy].
    Ugeskrift for laeger, 1993, Mar-08, Volume: 155, Issue:10

    Topics: Adenocarcinoma; Combined Modality Therapy; Fluorouracil; Hepatectomy; Humans; Leucovorin; Liver Neop

1993
[A new sequential chemotherapy of methotrexate with 5-fluorouracil against advanced colo-rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; D

1993
Preoperative chemotherapy and radiation therapy for locally advanced primary and recurrent rectal carcinoma. A report of surgical morbidity.
    Cancer, 1993, Jun-01, Volume: 71, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality

1993
[Medical treatment of colorectal cancers: evaluation].
    Annales de gastroenterologie et d'hepatologie, 1993, Volume: 29, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colon

1993
Endorectal ultrasound of T3 and T4 rectal cancers after preoperative chemoradiation.
    Diseases of the colon and rectum, 1996, Volume: 39, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil; Follow

1996
Preoperative "chemoradiation" for stages II and III rectal carcinoma.
    Archives of surgery (Chicago, Ill. : 1960), 1996, Volume: 131, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineopl

1996
Preoperative adjuvant radiation with chemotherapy for rectal cancer: its impact on stage of disease and the role of endorectal ultrasound.
    Annals of surgical oncology, 1996, Volume: 3, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorour

1996
The effect of tirapazamine (SR-4233) alone or combined with chemotherapeutic agents on xenografted human tumours.
    British journal of cancer, 1996, Volume: 73, Issue:12

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleo

1996
Preoperative treatment of patients with locally advanced unresectable rectal adenocarcinoma utilizing continuous chronobiologically shaped 5-fluorouracil infusion and radiation therapy.
    Cancer, 1996, Jul-15, Volume: 78, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Antimetabolites, Antineoplastic; Cohort Studies; Combined M

1996
Curative reoperations for locally recurrent rectal cancer.
    Diseases of the colon and rectum, 1996, Volume: 39, Issue:7

    Topics: Antimetabolites, Antineoplastic; Carcinoma; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Ma

1996
Locally advanced rectal cancer: resection and intraoperative radiotherapy using the flab method combined with preoperative or postoperative radiochemotherapy.
    Diseases of the colon and rectum, 1996, Volume: 39, Issue:7

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Fluorouracil; Humans; Intraoperative Period

1996
Thymidylate synthase in advanced gastrointestinal and breast cancers.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35, Issue:4

    Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; Biopsy; Breast Neoplasms; Colonic Neoplasms; Fem

1996
Suppository delivery of 5-fluorouracil in rectal cancer.
    Annals of surgical oncology, 1996, Volume: 3, Issue:3

    Topics: Administration, Rectal; Animals; Antimetabolites, Antineoplastic; Chromatography, High Pressure Liqu

1996
Application of anticancer agent embolism in Miles' operation.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1995, Volume: 15, Issue:3

    Topics: Adult; Blood Loss, Surgical; Chemoembolization, Therapeutic; Combined Modality Therapy; Female; Fluo

1995
[Dual biochemical modulation therapy using 5-FU, leucovorin and cisplatin on human rectal carcinoma xenografts in nude mouse].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fe

1996
[Regression of 4th-stage cancer of the rectum].
    Khirurgiia, 1996, Issue:2

    Topics: Adenocarcinoma; Combined Modality Therapy; Female; Fluorouracil; Humans; Middle Aged; Rectal Neoplas

1996
Comparison by carcinoembryonic antigen doubling time of hepatic injection and infusion for unresectable hepatic metastasis from colorectal cancer.
    Surgical oncology, 1995, Volume: 4, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoembryonic Antigen; Colonic Neoplasms; Female; F

1995
[Preoperative chemoradiation therapy for lower rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

1996
Ileostomy dysfunction with adjuvant chemoradiation for rectal carcinoma requiring in-hospital management: a cause for concern.
    The Australian and New Zealand journal of surgery, 1996, Volume: 66, Issue:9

    Topics: Antimetabolites, Antineoplastic; Carcinoma; Chemotherapy, Adjuvant; Dehydration; Fluorouracil; Hospi

1996
Modified clearing technique to identify lymph node metastases in post-irradiated surgical specimens from rectal adenocarcinoma.
    Archives of medical research, 1996,Spring, Volume: 27, Issue:1

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorouracil; Humans; Ly

1996
Preoperative radiotherapy for rectal cancer: benefits and controversies.
    Annals of surgical oncology, 1996, Volume: 3, Issue:5

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Fluorouracil; Humans; Neopl

1996
Month-long postoperative radiotherapy and 5-FU improve survival in rectal cancer.
    Oncology (Williston Park, N.Y.), 1996, Volume: 10, Issue:9

    Topics: Antimetabolites, Antineoplastic; Disease-Free Survival; Drug Administration Schedule; Fluorouracil;

1996
p53 gene mutation is not directly related to tumoricidal effects of preoperative radiochemohyperthermia therapy for rectal cancers.
    Journal of surgical oncology, 1996, Volume: 63, Issue:2

    Topics: Alleles; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Chromosome Deletion; Chromosomes,

1996
Progress in rectal cancer.
    Lancet (London, England), 1996, Dec-14, Volume: 348, Issue:9042

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy;

1996
Intraoperative electron and external beam irradiation with or without 5-fluorouracil and maximum surgical resection for previously unirradiated, locally recurrent colorectal cancer.
    Diseases of the colon and rectum, 1996, Volume: 39, Issue:12

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Combined Modality Therapy; Female;

1996
Locally advanced primary colorectal cancer: intraoperative electron and external beam irradiation +/- 5-FU.
    International journal of radiation oncology, biology, physics, 1997, Feb-01, Volume: 37, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Colonic Neoplasms; Combined Modalit

1997
"Sandwich" preoperative and postoperative combined chemotherapy and radiation in tethered and fixed rectal cancer: impact of treatment intensity on local control and survival.
    International journal of radiation oncology, biology, physics, 1997, Feb-01, Volume: 37, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Combined Mod

1997
Preliminary results of preoperative 5-fluorouracil, low-dose leucovorin, and concurrent radiation therapy for clinically resectable T3 rectal cancer.
    Diseases of the colon and rectum, 1997, Volume: 40, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clin

1997
Adjuvant therapy for colon and rectal cancer.
    American family physician, 1997, May-15, Volume: 55, Issue:7

    Topics: Algorithms; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined Mod

1997
[Adjuvant combined radiochemotherapy of rectum carcinoma with long-term 5-fluorouracil infusion].
    Zeitschrift fur Gastroenterologie, 1997, Volume: 35, Issue:3

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Fluorouracil; Hu

1997
Neoadjuvant treatment of local recurrence of rectal cancer: our experience.
    Journal of chemotherapy (Florence, Italy), 1997, Volume: 9, Issue:2

    Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemothe

1997
Retrospective comparative analysis of 5FU + low-dose folinic acid vs. 5FU + high-dose folinic acid in the treatment of metastatic colorectal cancer. The Ottawa experience.
    American journal of clinical oncology, 1997, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplast

1997
[The acute toxicity of the simultaneous radiochemotherapy of rectal carcinoma].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1997, Volume: 173, Issue:8

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Carcinoma; Chemotherapy, Adjuvant; Female; Fluoroura

1997
Pre-operative radiotherapy and chemotherapy for non-resectable rectal cancer.
    The Australian and New Zealand journal of surgery, 1997, Volume: 67, Issue:9

    Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Male; M

1997
[Adjuvant treatment in operable colonic and rectal cancer. A new possibility].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1997, Aug-30, Volume: 117, Issue:20

    Topics: Adjuvants, Immunologic; Antimetabolites, Antineoplastic; Colonic Neoplasms; Combined Modality Therap

1997
Synergistic effects of hyperthermia in preoperative radiochemotherapy for rectal carcinoma.
    Diseases of the colon and rectum, 1997, Volume: 40, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents; Combined Modality Therapy; Evaluatio

1997
[Arterial infusion chemotherapy in pelvic space for advanced rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:12

    Topics: Antidotes; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Drug Administration Schedule; Fl

1997
[A case of multiple liver metastasis and local recurrence from rectal cancer effectively treated by arterial infusion chemotherapy using low-dose 5-fluorouracil, cisplatin and LV].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:12

    Topics: Adult; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Sch

1997
[Circadian chemotherapy in cancer patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:12

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Circadian Rhythm; Drug Administration Schedule; Female

1997
[Preoperative chemoradiation therapy for advanced rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:14

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma,

1997
[Long-term complete response in two cases of liver metastases from rectal and gastric cancer treated with intra-arterial infusion chemotherapy of leucovorin and 5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:14

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule;

1997
Suppository administration of chemotherapeutic drugs with concomitant radiation for rectal cancer.
    Diseases of the colon and rectum, 1997, Volume: 40, Issue:12

    Topics: Adenocarcinoma; Administration, Rectal; Animals; Antibiotics, Antineoplastic; Chromatography, High P

1997
[Role of sodium selenite as an adjuvant in radiotherapy of rectal carcinoma].
    Medizinische Klinik (Munich, Germany : 1983), 1997, Sep-15, Volume: 92 Suppl 3

    Topics: Antioxidants; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Administration Schedule; Femal

1997
Locally advanced rectal cancer: surgical complications after infusional chemotherapy and radiation therapy.
    Radiology, 1998, Volume: 206, Issue:1

    Topics: Actuarial Analysis; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil

1998
[The formation of a small intestine-large intestine anastomosis: the end to the side method].
    Klinichna khirurhiia, 1997, Issue:5-6

    Topics: Animals; Antineoplastic Agents; Dogs; Fluorouracil; Humans; Radiation Dosage; Rectal Neoplasms; Retr

1997
[Palliative treatment with cytostatics of metastatic colorectal cancer in general practice. A model].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1997, Nov-10, Volume: 117, Issue:27

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Colonic Neoplasms; Drug Administration

1997
[No improvement of therapeutic results by modulation of 5-fluorouracil with leucovorin and/or levamisole in adjuvant radiochemotherapy in rectal carcinoma].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1997, Volume: 173, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Leu

1997
Analysis of histological therapeutic effect, apoptosis rate and p53 status after combined treatment with radiation, hyperthermia and 5-fluorouracil suppositories for advanced rectal cancers.
    British journal of cancer, 1998, Volume: 77, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Combined Modality Therapy; DNA Fragmentation; DNA, Neopl

1998
[A case of fluorouracil-induced pneumonitis].
    Nihon Kyobu Shikkan Gakkai zasshi, 1997, Volume: 35, Issue:10

    Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Drug Hypersensitivity; Fluorouracil; Hu

1997
Weekly 24-hour infusion of high-dose 5-fluorouracil and leucovorin in patients with advanced colorectal cancer: Taiwan experience.
    Japanese journal of clinical oncology, 1998, Volume: 28, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration

1998
[A case of hepatic metastasis of rectal cancer with familial adenomatous polyposis treated by transarterial administration of low-dose leucovorin and 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:3

    Topics: Adenomatous Polyposis Coli; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administrati

1998
Changes in tumor proliferation of rectal cancer induced by preoperative 5-fluorouracil and irradiation.
    Diseases of the colon and rectum, 1998, Volume: 41, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Cell Division; Combined Modality Therapy; Female; Fluorouracil; Huma

1998
Radiation and chemotherapy instead of surgery for low infiltrative rectal adenocarcinoma: a prospective trial.
    Annals of surgical oncology, 1998, Volume: 5, Issue:2

    Topics: Abdomen; Adenocarcinoma; Adjuvants, Immunologic; Anal Canal; Antidotes; Antimetabolites, Antineoplas

1998
Preoperative chemoradiation for extraperitoneal T3 rectal cancer: acute toxicity, tumor response, and sphincter preservation.
    International journal of radiation oncology, biology, physics, 1998, Mar-15, Volume: 40, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Pro

1998
[Continuous intraportal chemotherapy for prevention of metachronous hepatic metastasis in colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedul

1998
[Enhanced induction of apoptosis of human colorectal cancer cells after preoperative treatment with 5-fluorouracil its relationship to DNA ploidy pattern].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25 Suppl 3

    Topics: Adenocarcinoma; Apoptosis; Cell Cycle; Colonic Neoplasms; DNA, Neoplasm; Female; Flow Cytometry; Flu

1998
A rare event of 5-fluorouracil-associated peripheral neuropathy: a report of two patients.
    American journal of clinical oncology, 1998, Volume: 21, Issue:3

    Topics: Adenocarcinoma; Aged; Colonic Neoplasms; Combined Modality Therapy; Demyelinating Diseases; Female;

1998
[How I treat colorectal cancer. I. Prevention and adjuvant treatment].
    Revue medicale de Liege, 1998, Volume: 53, Issue:4

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Antimeta

1998
[Proliferation and apoptosis before and after preoperative simultaneous radiochemotherapy of rectal carcinomas].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1998, Volume: 174, Issue:6

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Apoptosis; Biomarkers, Tumor; Biopsy; Cell Division

1998
Costoclavicular pinching: a complication of long-term central venous catheters. A report of three cases.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:7

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Breast Neoplasms; Cathete

1998
[p53 expression and response to hepatic intraarterial infusion chemotherapy in patients with colorectal cancer metastasis to liver].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Administration Sc

1998
Combined preoperative radiation and mitomycin/5-fluorouracil treatment for locally advanced rectal adenocarcinoma.
    Journal of the American College of Surgeons, 1998, Volume: 187, Issue:2

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Mo

1998
The impact of 5-fluorouracil and intraoperative electron beam radiation therapy on the outcome of patients with locally advanced primary rectal and rectosigmoid cancer.
    Annals of surgery, 1998, Volume: 228, Issue:2

    Topics: Actuarial Analysis; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, A

1998
Low-dose cisplatin-5-fluorouracil prevents postoperative suppression of natural killer cell activity in patients with gastrointestinal cancer.
    Japanese journal of clinical oncology, 1998, Volume: 28, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Colectomy;

1998
Reinduction therapy with the same cytostatic regimen in patients with advanced colorectal cancer.
    British journal of cancer, 1998, Volume: 78, Issue:6

    Topics: Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Colonic Neoplasms; Disease Progression; Fem

1998
Low rectal cancer: impact of radiation and chemotherapy on surgical treatment.
    Diseases of the colon and rectum, 1998, Volume: 41, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antineoplastic Combined Chemo

1998
Low rectal cancer: impact of radiation and chemotherapy on surgical treatment.
    Diseases of the colon and rectum, 1998, Volume: 41, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antineoplastic Combined Chemo

1998
Low rectal cancer: impact of radiation and chemotherapy on surgical treatment.
    Diseases of the colon and rectum, 1998, Volume: 41, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antineoplastic Combined Chemo

1998
Low rectal cancer: impact of radiation and chemotherapy on surgical treatment.
    Diseases of the colon and rectum, 1998, Volume: 41, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antineoplastic Combined Chemo

1998
[Complete remission of liver metastasis from rectal cancer following continuous oral administration of tegafur-uracil after intrahepatic arterial single injection of CDDP and 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:11

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinat

1998
Alcohol consumption enhances liver metastasis in colorectal carcinoma patients.
    Cancer, 1998, Oct-15, Volume: 83, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Analysis of Variance; Antineoplastic Agents; Blood

1998
High dose rate intraoperative radiation therapy (HDR-IORT) as part of the management strategy for locally advanced primary and recurrent rectal cancer.
    International journal of radiation oncology, biology, physics, 1998, Sep-01, Volume: 42, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antidotes; Antimetabolites, Antineoplastic; Carcinom

1998
Preoperative radiation with concurrent 5-fluorouracil continuous infusion for locally advanced unresectable rectal cancer.
    International journal of radiation oncology, biology, physics, 1998, Sep-01, Volume: 42, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality T

1998
p53 immunohistochemical staining predicts residual disease after chemoradiation in patients with high-risk rectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Biopsy; Cell Dif

1997
Clinical applications of the histoculture drug response assay.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Cell Culture Techniques; Chemotherapy, Adjuvant; Colonic Neoplasms; Colorecta

1995
Supraventricular arrhythmia: a complication of 5-fluorouracil therapy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1998, Volume: 10, Issue:6

    Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atr

1998
[Prognostic factors in combined radiochemotherapy of the anal canal carcinoma].
    Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, 1998, Volume: 115

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy;

1998
The effectiveness of chemotherapy with cisplatin and 5-fluorouracil for recurrent small cell neuroendocrine carcinoma of the rectum: report of a case.
    Surgery today, 1999, Volume: 29, Issue:2

    Topics: Adenoma, Villous; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Carcino

1999
Five fractions of preoperative radiotherapy for selected cases of rectal carcinoma: long-term tumor control and tolerance to treatment.
    International journal of radiation oncology, biology, physics, 1999, Feb-01, Volume: 43, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antidotes; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant;

1999
Inguinal lymph node metastases from rectal adenocarcinoma.
    Journal of surgical oncology, 1999, Volume: 70, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colostomy; Combined Mod

1999
[An addendum to the article by C. Rödel, W. Hohenberger, R. Sauer. Adjuvant and neoadjuvant radiochemotherapy of rectal carcinoma. Strahlenther Onkol 1998; 174: 497-504 (Nr. 10)].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1999, Volume: 175, Issue:3

    Topics: Antimetabolites, Antineoplastic; Carcinoma; Chemotherapy, Adjuvant; Fluorouracil; Humans; Radiothera

1999
High inter- and intrapatient variation in 5-fluorouracil plasma concentrations during a prolonged drug infusion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chronotherapy; Colonic Neoplasms; Digestive System Neo

1999
[Palliative chemotherapy in colorectal cancer--can we afford it?].
    Ugeskrift for laeger, 1999, Jun-21, Volume: 161, Issue:25

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Denmark; Drug Costs; Fluorouracil

1999
Tumor downstaging and sphincter preservation with preoperative chemoradiation in locally advanced rectal cancer: the M. D. Anderson Cancer Center experience.
    International journal of radiation oncology, biology, physics, 1999, Jul-15, Volume: 44, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Combined Modality Thera

1999
[Total pelvic exenteration and rectal cancer. Apropos of 20 cases].
    Chirurgie; memoires de l'Academie de chirurgie, 1999, Volume: 124, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Che

1999
Prognostic implications of response to preoperative infusional chemoradiation in locally advanced rectal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1999, Volume: 51, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; Flu

1999
Experience with 5-fluoro-uracil and levamisole in the management of advanced rectal carcinoma.
    African journal of medicine and medical sciences, 1996, Volume: 25, Issue:3

    Topics: Adjuvants, Immunologic; Adult; Antimetabolites, Antineoplastic; Colostomy; Combined Modality Therapy

1996
Colorectal cancer.
    Lancet (London, England), 1999, Mar-20, Volume: 353, Issue:9157

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv

1999
Infusional 5-fluorouracil can be a pain in the neck: A case for repositioning displaced Hickman lines.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1999, Volume: 11, Issue:4

    Topics: Aged; Antimetabolites, Antineoplastic; Catheterization, Central Venous; Fluorouracil; Humans; Infusi

1999
[A case of local recurrence of rectal cancer responding to local intraarterial infusion therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:9

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Huma

1999
Pathology of rectal adenocarcinoma following preoperative adjuvant radiotherapy and chemotherapy.
    The Ulster medical journal, 1999, Volume: 68, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Female; Fibrosis;

1999
Continuous infusion 5-fluorouracil as salvage chemotherapy in patients with advanced colorectal cancer.
    Annals of the Academy of Medicine, Singapore, 1999, Volume: 28, Issue:2

    Topics: Antimetabolites, Antineoplastic; Carcinoma; Catheterization, Central Venous; Cohort Studies; Colonic

1999
Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer.
    The Australian and New Zealand journal of surgery, 1999, Volume: 69, Issue:10

    Topics: Abscess; Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic;

1999
Pre-operative chemoradiotherapy in locally advanced rectal cancer.
    The Australian and New Zealand journal of surgery, 1999, Volume: 69, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antimetabolites, Antineoplast

1999
Preoperative combined radiotherapy and chemotherapy for rectal cancer does not affect early postoperative morbidity and mortality in low anterior resection.
    Diseases of the colon and rectum, 1999, Volume: 42, Issue:10

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carboplatin; Case-Control St

1999
Improved outcome following preoperative radiochemotherapy: 40.5 Gy accelerated hyperfractionation and 5-fluorouracil suppositories for patients with carcinoma of the lower rectum.
    Surgery today, 1999, Volume: 29, Issue:10

    Topics: Administration, Rectal; Aged; Antimetabolites, Antineoplastic; Carcinoma; Case-Control Studies; Comb

1999
[Efficacy of adjuvant hepatic arterial infusion chemotherapy following resection of colorectal liver metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Colonic Neoplasms; Combined Modalit

1999
Irinotecan combined with bolus fluorouracil, continuous infusion fluorouracil, and high-dose leucovorin every two weeks (LV5FU2 regimen): a clinical dose-finding and pharmacokinetic study in patients with pretreated metastatic colorectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:9

    Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neopla

1999
Rectal cancer and inguinal metastases: prognostic role and therapeutic indications.
    Diseases of the colon and rectum, 1999, Volume: 42, Issue:11

    Topics: Abdominal Neoplasms; Adenocarcinoma; Aged; Aged, 80 and over; Biopsy; Female; Fluorouracil; Follow-U

1999
P53 alterations have no prognostic or predictive significance in Dukes' C rectal carcinomas.
    International journal of oncology, 1999, Volume: 15, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; DNA, Neoplasm; Drug Therapy, C

1999
Chemoradiation with or without intraoperative radiation therapy in patients with locally recurrent rectal carcinoma: prognostic factors and long term outcome.
    Cancer, 1999, Dec-15, Volume: 86, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combi

1999
Malar metastasis from rectal carcinoma: a case report.
    The American surgeon, 1999, Volume: 65, Issue:12

    Topics: Adenocarcinoma; Antidotes; Antimetabolites, Antineoplastic; Colonic Neoplasms; Fatal Outcome; Female

1999
Preoperative chemoradiation with cisplatin and 5-fluorouracil for extraperitoneal T3 rectal cancer: acute toxicity, tumor response, sphincter preservation.
    International journal of radiation oncology, biology, physics, 1999, Dec-01, Volume: 45, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Cisplati

1999
Changes in apoptotic and mitotic activity in rectal carcinoma after short-term cytostatic therapy as possible predictive factors.
    Neoplasma, 1999, Volume: 46, Issue:4

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Apoptosis; Carcinoembryonic Antigen; Female;

1999
[Long-term complete response in a case of unresectable rectal cancer following chemoradiation].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy

2000
Cisplatin-5-fluorouracil therapy with remarkable effect and 5-year survival for paraaortic lymph node metastases of rectal carcinoma in females: a case report.
    Japanese journal of clinical oncology, 1999, Volume: 29, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Aorta; Cisplatin; Female; Fluo

1999
Investigation of the comparative toxicity of 5-FU bolus versus 5-FU continuous infusion circadian chemotherapy with concurrent radiation therapy in locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2000, Mar-01, Volume: 46, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Chronotherapy; Disease-Free Su

2000
Preoperative chemoradiation in fixed distal rectal cancer: dose time factors for pathological complete response.
    International journal of radiation oncology, biology, physics, 2000, Mar-01, Volume: 46, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Diarrhea

2000
Sphincter-sparing surgery after preoperative radiotherapy for low rectal cancers: feasibility, oncologic results and quality of life outcomes.
    British journal of cancer, 2000, Volume: 82, Issue:6

    Topics: Aged; Anal Canal; Antimetabolites, Antineoplastic; Cohort Studies; Combined Modality Therapy; Feasib

2000
Preoperative carcinoembryonic antigen level as an independent prognostic factor in colorectal cancer: Taiwan experience.
    Japanese journal of clinical oncology, 2000, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Age Factors; Analysis of Variance; Antimetabolites, Antineoplastic; Carcinoembryonic

2000
Change of telomerase activity in rectal cancer with chemoradiation therapy.
    Journal of Korean medical science, 2000, Volume: 15, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cisplatin; Combined Modality Th

2000
Preoperative radiation with concurrent 5-fluorouracil for locally advanced T4-primary rectal cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2000, Volume: 176, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female;

2000
Prospective assessment of primary rectal cancer response to preoperative radiation and chemotherapy using 18-fluorodeoxyglucose positron emission tomography.
    Diseases of the colon and rectum, 2000, Volume: 43, Issue:1

    Topics: Adenocarcinoma, Mucinous; Antimetabolites, Antineoplastic; Fluorodeoxyglucose F18; Fluorouracil; Gly

2000
Targeted chemoembolization of tumors with poly(2-hydroxyethyl methacrylate) particles.
    Journal of biomedical materials research, 2000, Volume: 51, Issue:2

    Topics: Anticoagulants; Carcinoid Tumor; Chemoembolization, Therapeutic; Colonic Neoplasms; Dalteparin; Doxo

2000
Prospective trial of preoperative concomitant boost radiotherapy with continuous infusion 5-fluorouracil for locally advanced rectal cancer.
    International journal of radiation oncology, biology, physics, 2000, Jun-01, Volume: 47, Issue:3

    Topics: Adult; Aged; Anal Canal; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorou

2000
A pilot study of preoperative continuous infusion 5-fluorouracil, external microwave hyperthermia, and external beam radiotherapy for treatment of locally advanced, unresectable, or recurrent rectal cancer.
    International journal of radiation oncology, biology, physics, 2000, Jun-01, Volume: 47, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Feasibility Studies; Female

2000
[Initial locoregional chemotherapy in recurrent and locoregional advanced or inoperable stages of pelvic uterine and anorectal cancers].
    Bulletin du cancer, 1995, Volume: 82, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bleomycin; Cisplatin; D

1995
Continuous intra-arterial 5-FU chemotherapy in a patient with a repeated recurrence of rectal cancer: report of a case.
    Diseases of the colon and rectum, 2000, Volume: 43, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Carcinoembryonic Antigen; Fluorouracil; Humans; Infusions, In

2000
Pre-operative chemo-radiotherapy in locally advanced rectal cancer: is this the way of future management?
    Australasian radiology, 1999, Volume: 43, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Dose Fra

1999
Cost-effectiveness of hepatic arterial chemoembolization for colorectal liver metastases refractory to systemic chemotherapy.
    Radiology, 2000, Volume: 216, Issue:2

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Benchmarking; C

2000
High-dose-rate intraoperative brachytherapy for recurrent colorectal cancer.
    International journal of radiation oncology, biology, physics, 2000, Aug-01, Volume: 48, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brachytherapy; Colonic Neopla

2000
[A case of advanced rectal cancer with unresectable liver metastasis for which chemotherapy was markedly effective].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:10

    Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Combined Modal

2000
Absorbable mesh sling prevents radiation-induced bowel injury during "sandwich" chemoradiation for rectal cancer.
    Archives of surgery (Chicago, Ill. : 1960), 2000, Volume: 135, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Case-Control Studies; Chemotherapy, Adjuvant; Dose-Response Relationshi

2000
Combined preoperative chemotherapy and radiation for locally advanced rectal carcinoma.
    American journal of clinical oncology, 2000, Volume: 23, Issue:5

    Topics: Anal Canal; Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorouracil; Humans; Radiot

2000
Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy.
    Gastroenterology, 2000, Volume: 119, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Base Pair Mismatch;

2000
Severe heart failure secondary to 5-fluorouracil and low-doses of folinic acid: usefulness of an intra-aortic balloon pump.
    Critical care medicine, 2000, Volume: 28, Issue:10

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Critical Care; Drug Monitoring; Drug Therapy,

2000
[The importance of delay in patients with tumors exemplified by pretreatment of locally advanced rectal carcinoma].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2000, Volume: 176, Issue:10

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Endosonography; Fluorouracil; Humans; Le

2000
Prognostic significance of postchemoradiation stage following preoperative chemotherapy and radiation for advanced/recurrent rectal cancers.
    International journal of radiation oncology, biology, physics, 2000, Nov-01, Volume: 48, Issue:4

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies;

2000
[A study of liver metastasis from colorectal cancer in which hepatic resection was performed after hepatic arterial infusion chemotherapy].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2000, Volume: 97, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Combined Modalit

2000
[Intra-arterial infusion therapy for unresectable liver metastasis of colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoembryonic Antigen; Colonic Neop

2000
[Evaluation by FDG-PET of arterial infusion chemotherapy for unresectable metastatic liver tumor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Female; Fluorodeoxyglucose F18; Fluorouracil; Hepatic Artery;

2000
[A case of locally advanced rectal carcinoma with liver metastasis treated with a combination of CRT, HAI, and systemic chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:12

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Combined Modality

2000
Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:12

    Topics: Adult; Aged; Alleles; Antimetabolites, Antineoplastic; Breast Neoplasms; Colonic Neoplasms; Dihydrou

2000
Thymidylate synthase protein expression in primary colorectal cancer compared with the corresponding distant metastases and relationship with the clinical response to 5-fluorouracil.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Colorectal Neoplasm

2000
Effective pelvic symptom control using initial chemoradiation without colostomy in metastatic rectal cancer.
    International journal of radiation oncology, biology, physics, 2001, Jan-01, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antimetabolites, Antineoplastic; Cohort Studie

2001
Intraoperative radiation therapy for locally advanced recurrent rectal or rectosigmoid cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2001, Volume: 58, Issue:1

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; D

2001
Quantitative short-term study of anal sphincter function after chemoradiation for rectal cancer.
    Archives of surgery (Chicago, Ill. : 1960), 2001, Volume: 136, Issue:2

    Topics: Adenocarcinoma; Aged; Anal Canal; Antimetabolites, Antineoplastic; Case-Control Studies; Female; Flu

2001
[Long survival in a case of unresectable hepatic metastasis from rectal carcinoma treated with second-look hepatectomy plus pharmacokinetic modulating chemotherapy (PMC)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:1

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dru

2001
Idiosyncratic reaction after oxaliplatin infusion.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chills; Fever; Fluorouracil;

2001
Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Mar-15, Volume: 19, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Disease-Free Survival; Female; Fluorouracil; Gene Expr

2001
Drug-induced modulation of carcinoembryonic antigen (CEA) expression in neoplastic cells from a patient with rectal cancer.
    Journal of experimental & clinical cancer research : CR, 2000, Volume: 19, Issue:4

    Topics: Adult; Carcinoembryonic Antigen; Female; Flow Cytometry; Fluorouracil; Humans; Interferon-gamma; Rec

2000
Intraoperative irradiation for locally recurrent colorectal cancer in previously irradiated patients.
    International journal of radiation oncology, biology, physics, 2001, Apr-01, Volume: 49, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Antimetabolites, Antineoplastic; Colonic Neoplasms; Female; Fluor

2001
Tumor microcirculation evaluated by dynamic magnetic resonance imaging predicts therapy outcome for primary rectal carcinoma.
    Cancer research, 2001, Mar-15, Volume: 61, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorouraci

2001
External beam radiotherapy for synchronous rectal and prostatic tumors.
    Urology, 2001, Volume: 57, Issue:4

    Topics: Adenocarcinoma; Aged; Chemotherapy, Adjuvant; Fluorouracil; Follow-Up Studies; Humans; Male; Neoplas

2001
Neoadjuvant therapy for adenocarcinoma of the rectum: tumor response and acute toxicity.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm

2001
Addition of oxaliplatin to continuous fluorouracil, l-folinic acid, and concomitant radiotherapy in rectal cancer: the Lyon R 97-03 phase I trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, May-01, Volume: 19, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

2001
[Treatment of rectal carcinoma].
    Rontgenpraxis; Zeitschrift fur radiologische Technik, 2001, Volume: 53, Issue:5

    Topics: Antimetabolites, Antineoplastic; Brachytherapy; Combined Modality Therapy; Drug Therapy, Combination

2001
P27kip1 expression is associated with tumor response to preoperative chemoradiotherapy in rectal cancer.
    Annals of surgical oncology, 2001, Volume: 8, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cell Cycle Proteins; Combined Modal

2001
Neoadjuvant chemoradiation for rectal cancer: analysis of clinical outcomes from a 13-year institutional experience.
    Annals of surgery, 2001, Volume: 233, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisp

2001
[Successful resection of multiple liver metastases from rectal cancer following initial treatment using hepatic arterial infusion chemotherapy and radiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Adm

2001
[A case of multiple liver metastases from rectal carcinoid tumor successfully treated with arterial infusion chemotherapy using degradable starch microspheres (DSM)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2001, Volume: 98, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Cisplatin; Drug Administration Sche

2001
Adjuvant postoperative 5-fluorouracil chemotherapy combined with pelvic radiation for rectal cancer: results from an Asian population.
    Cancer investigation, 2001, Volume: 19, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Agranulocytosis; Antimetabolites, Antineoplastic; Ch

2001
Acute lung injury associated with 5-fluorouracil and oxaliplatinum combined chemotherapy.
    The European respiratory journal, 2001, Volume: 18, Issue:1

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Lung; Male; Mid

2001
T4 rectal cancer treated with preoperative chemoradiation to the posterior pelvis followed by multivisceral resection: patterns of failure and limitations of treatment.
    International journal of radiation oncology, biology, physics, 2001, Sep-01, Volume: 51, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Mo

2001
[Therapy results of locoregional recurrences in rectal cancer].
    Zentralblatt fur Chirurgie, 2001, Volume: 126, Issue:8

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Antimetabolites, Antineoplastic; Combined Modality Therapy

2001
[Anastomotic protection with a transanal tube after rectum resection and total mesorectal excision].
    Zentralblatt fur Chirurgie, 2001, Volume: 126, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antimetabolites, Antineoplastic; Combined Mod

2001
Preoperative chemoradiotherapy and radical surgery for locally advanced distal rectal adenocarcinoma: pathologic findings and clinical implications.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv

2001
Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)- related toxicity compared with controls.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:9

    Topics: Adult; Aged; Alternative Splicing; Antimetabolites, Antineoplastic; Breast Neoplasms; Colonic Neopla

2001
Fatigue during preoperative chemoradiation for resectable rectal cancer.
    Cancer, 2001, Sep-15, Volume: 92, Issue:6 Suppl

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Fatigue; Female; Fluorourac

2001
Preoperative radiochemotherapy and sphincter-saving resection for T3 carcinomas of the lower third of the rectum.
    Annals of surgery, 2001, Volume: 234, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Anastomosis, Surgical; Antineoplastic Agents; Colon; Combin

2001
Pathologic downstaging of T3-4Nx rectal cancer after chemoradiation: 5-fluorouracil vs. Tegafur.
    International journal of radiation oncology, biology, physics, 2001, Dec-01, Volume: 51, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female;

2001
Transanal excision for T1 and T2 rectal cancer--efficacy of local resection vs. adjuvant therapy. Extended abstract.
    Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera, 2001, Volume: 7, Issue:6

    Topics: Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Dose Fractionation, Radiat

2001
Complete response to neoadjuvant chemoradiation for rectal cancer does not influence survival.
    Annals of surgical oncology, 2001, Volume: 8, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Colectomy;

2001
The dose-volume relationship of acute small bowel toxicity from concurrent 5-FU-based chemotherapy and radiation therapy for rectal cancer.
    International journal of radiation oncology, biology, physics, 2002, Jan-01, Volume: 52, Issue:1

    Topics: Acute Disease; Adenocarcinoma; Analysis of Variance; Antimetabolites, Antineoplastic; Combined Modal

2002
Preoperative neoadjuvant therapy for rectal cancer also enables autologous transfusion.
    Diseases of the colon and rectum, 2002, Volume: 45, Issue:1

    Topics: Antimetabolites, Antineoplastic; Blood Transfusion, Autologous; Fluorouracil; Humans; Neoadjuvant Th

2002
[Efficacy of postoperative adjuvant chemotherapy for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:1

    Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic

2002
[The proper opportunity of surgery for rectal cancer after preoperative adjuvant chemotherapy].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1999, Volume: 37, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil;

1999
[Effects of selective preoperative intra-arterial infusion chemotherapy on apoptosis and proliferation of rectal cancer cells].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2000, Volume: 38, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Cisplati

2000
Apoptosis as a cellular predictor for histopathologic response to neoadjuvant radiochemotherapy in patients with rectal cancer.
    International journal of radiation oncology, biology, physics, 2002, Feb-01, Volume: 52, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Chemotherapy, Adjuvant; Dise

2002
[A case of hepatic metastasis from rectal carcinoma successfully treated with pharmacokinetic modulating chemotherapy (PMC)-CPT-11 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Combined Modality

2002
Rationale for a phase I/II radiation dose-escalation study with concurrent amifostine (Ethyol) and infusional 5-FU chemotherapy for preoperative treatment of unresectable or locally recurrent rectal carcinoma.
    Seminars in radiation oncology, 2002, Volume: 12, Issue:1 Suppl 1

    Topics: Adenocarcinoma; Amifostine; Antimetabolites, Antineoplastic; Clinical Trials, Phase I as Topic; Clin

2002
[A case of liver metastasis of rectal cancer demonstrating complete response to 5-FU + Leucovorin + UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug C

2002
[A case of recurrent rectal cancer responding to weekly low-dose CPT-11/isovorin/5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Fl

2002
A breakthrough in cryosurgery.
    Surgical endoscopy, 2002, Volume: 16, Issue:5

    Topics: Antimetabolites, Antineoplastic; Bronchial Fistula; Carcinoma; Cryosurgery; Fistula; Fluorouracil; H

2002
Preoperative radiation with or without chemotherapy and full-thickness transanal excision for selected T2 and T3 distal rectal cancers.
    International journal of colorectal disease, 2002, Volume: 17, Issue:1

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Comorbidity; Femal

2002
Use of adjuvant chemotherapy and radiation therapy for rectal cancer among the elderly: a population-based study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jun-01, Volume: 20, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Comor

2002
Does downstaging predict improved outcome after preoperative chemoradiation for extraperitoneal locally advanced rectal cancer? A long-term analysis of 165 patients.
    International journal of radiation oncology, biology, physics, 2002, Jul-01, Volume: 53, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2002
Does downstaging predict improved outcome after preoperative chemoradiation for extraperitoneal locally advanced rectal cancer? A long-term analysis of 165 patients.
    International journal of radiation oncology, biology, physics, 2002, Jul-01, Volume: 53, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2002
Does downstaging predict improved outcome after preoperative chemoradiation for extraperitoneal locally advanced rectal cancer? A long-term analysis of 165 patients.
    International journal of radiation oncology, biology, physics, 2002, Jul-01, Volume: 53, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2002
Does downstaging predict improved outcome after preoperative chemoradiation for extraperitoneal locally advanced rectal cancer? A long-term analysis of 165 patients.
    International journal of radiation oncology, biology, physics, 2002, Jul-01, Volume: 53, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2002
Mesorectal microfoci adversely affect the prognosis of patients with rectal cancer.
    Diseases of the colon and rectum, 2002, Volume: 45, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2002
Capecitabine can induce acute coronary syndrome similar to 5-fluorouracil.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:5

    Topics: Administration, Oral; Angina Pectoris; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Dose-Res

2002
Letter: 5-Fluorouracil and angina.
    Lancet (London, England), 1975, Feb-08, Volume: 1, Issue:7902

    Topics: Adult; Aged; Angina Pectoris; Female; Fluorouracil; Humans; Infusions, Parenteral; Injections, Intra

1975
Cancer of the colon and rectum. A review.
    Postgraduate medicine, 1975, Volume: 57, Issue:4

    Topics: Barium Sulfate; Carcinoembryonic Antigen; Colonic Neoplasms; Cystadenoma; Electrocoagulation; Fiber

1975
The value of combined 5-fluorouracil and x-ray therapy in the palliation of locally recurrent and inoperable rectal carcinoma.
    Clinical radiology, 1975, Volume: 26, Issue:2

    Topics: Fluorouracil; Humans; Neoplasm Recurrence, Local; Palliative Care; Radiotherapy Dosage; Rectal Neopl

1975
Letter: Immunotherapy for colorectal cancer.
    Lancet (London, England), 1976, Jun-19, Volume: 1, Issue:7973

    Topics: BCG Vaccine; Colonic Neoplasms; Evaluation Studies as Topic; Fluorouracil; Humans; Rectal Neoplasms

1976
[Incurable colorectal cancer. Possibilities and limits of differentiated therapy (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1977, Aug-05, Volume: 119, Issue:31

    Topics: Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Palliative Care; Recta

1977
Failure of methyl-C.C.N.U. and 5-fluorouracil in colorectal cancer.
    Lancet (London, England), 1978, Jul-08, Volume: 2, Issue:8080

    Topics: Adult; Aged; Colonic Neoplasms; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Female; Flu

1978
[Chemotherapy of colorectal carcinomas].
    Deutsche medizinische Wochenschrift (1946), 1978, Sep-22, Volume: 103, Issue:38

    Topics: Adenocarcinoma; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Lomustine; Palli

1978
[The state of chemotherapy of colorectal neoplasms].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1978, Issue:14

    Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Lomustine

1978
Non-surgical palliation of carcinoma of the rectum.
    The Practitioner, 1979, Volume: 222, Issue:1331

    Topics: Adult; Aged; Female; Fluorouracil; Humans; Male; Middle Aged; Palliative Care; Rectal Neoplasms; Ter

1979
Colorectal carcinoma: overview of management techniques.
    Postgraduate medicine, 1979, Volume: 66, Issue:3

    Topics: BCG Vaccine; Carcinoembryonic Antigen; Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; Radioth

1979
Prolonged and continuous percutaneous intra-arterial hepatic infusion chemotherapy in advanced metastatic liver adenocarcinoma from colorectal primary.
    Cancer, 1979, Volume: 44, Issue:2

    Topics: Adenocarcinoma; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusi

1979
Carcinoma of the rectum in adolescence.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:6

    Topics: Adenocarcinoma, Mucinous; Adolescent; Age Factors; Cyclophosphamide; Fluorouracil; Humans; Hydroneph

1975
Clinical management of advanced gastrointestinal cancer.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Adenoma, Islet Cell; Carcinoma, Hepatocellular; Carmustine; Colonic Neoplasms; Cytarabine; Drug Ther

1975
Walter Hubert lecture Chemotherapy of upper gastrointestinal carcinoma.
    British journal of cancer, 1976, Volume: 34, Issue:3

    Topics: Adenoma, Islet Cell; Antineoplastic Agents; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, S

1976
Colorectal carcinoma in adolescents implications regarding etiology.
    Cancer, 1977, Volume: 40, Issue:5 Suppl

    Topics: Adenocarcinoma, Mucinous; Adolescent; Adult; Child; Colonic Neoplasms; Female; Fluorouracil; Humans;

1977
Current trends and prospects in surgical adjuvant trials.
    Archiv fur Geschwulstforschung, 1978, Volume: 48, Issue:7

    Topics: Antineoplastic Agents; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Dianhydroga

1978
[Status and problems of the treatment of metastatic rectal cancer].
    Acta medica Austriaca. Supplement, 1979, Volume: 6

    Topics: Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Lomustine; Neoplasm Recurren

1979
Treatment of hepatic metastases by percutaneous hepatic arterial infusion.
    Cancer, 1979, Volume: 43, Issue:6

    Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gastroint

1979
[Therapeutic effect of ftorafur].
    Veterinariia, 1977, Issue:1

    Topics: Adenocarcinoma; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Female; Fluorouracil; Mammary Gland

1977
Chemoimmunotherapy of metastatic large bowel cancer: nonspecific stimulation with BCG and levamisole.
    Cancer, 1977, Volume: 40, Issue:5 Suppl

    Topics: BCG Vaccine; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Levamisole; Lomusti

1977
Phase II clinical trial of ftorafur in 5-fluorouracil-refractory colorectal cancer.
    Cancer treatment reports, 1977, Volume: 61, Issue:8

    Topics: Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Re

1977
Chemoimmunotherapy with BCG and FT 207 (II).
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1978, May-01, Volume: 47, Issue:3

    Topics: BCG Vaccine; Colonic Neoplasms; Fluorouracil; Humans; Rectal Neoplasms; Tegafur

1978
Phase II evaluation of ftorafur in previously untreated colorectal cancer: a Southwest Oncology Group Study.
    Cancer, 1979, Volume: 44, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Central Nervous System; Colonic Neoplasms; Drug Evaluation; Female; Flu

1979
Phase I-II study of ftorafur and methyl-CCNU in advanced colorectal cancer.
    Cancer, 1979, Volume: 44, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Bone Marrow; Colonic Neoplasms; Digestive System; Drug Evaluation; Drug

1979
Treatment of advanced gastrointestinal cancer with 5-fluorouracil and mitomycin C.
    Cancer, 1979, Volume: 43, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gas

1979
Phase II study of 5-fluorouracil, methyl-CCNU, and daunorubicin in colorectal cancer: a Cancer and Leukemia Group B study.
    Cancer treatment reports, 1979, Volume: 63, Issue:2

    Topics: Adenocarcinoma; Colonic Neoplasms; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Female;

1979
Intraarterial infusion chemotherapy (5-fluorouracil) in patients with inextirpable or locally recurrent rectal cancer.
    American journal of surgery, 1979, Volume: 137, Issue:6

    Topics: Adult; Aged; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Neoplasm Me

1979
Delayed complications in colo-rectal carcinoma treated by combination radiotherapy and 5-fluorouracil--Eastern Cooperative Oncology Group (E.C.O.G.) pilot study.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:3

    Topics: Aged; Colonic Diseases; Colonic Neoplasms; Connective Tissue; Constriction, Pathologic; Female; Fluo

1979
Five-day continuous infusion of 5-fluorouracil for advanced colorectal, gastric, and pancreatic adenocarcinoma.
    Journal of surgical oncology, 1979, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infus

1979
Combination chemotherapy with 5-fluorouracil and methyl-CCNU for the treatment of advanced gastrointestinal cancer.
    Tumori, 1979, Jun-30, Volume: 65, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Blood Cells; Colonic Neoplasms; Drug Administration Schedule; Dr

1979
[Experience with weekly intravenous 5-fluorouracil in advanced colonic and rectal neoplasms].
    Revista espanola de las enfermedades del aparato digestivo, 1979, Volume: 55, Issue:4

    Topics: Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Int

1979
Results of a prospective randomized study of hepatic artery infusion with 5-fluorouracil vs. intravenous 5-fluorouracil in patients with hepatic metastases from colo-rectal cancer: a Central Oncology Group Study (COG 7032).
    Frontiers of gastrointestinal research, 1979, Volume: 5

    Topics: Colonic Neoplasms; Evaluation Studies as Topic; Fluorouracil; Hepatic Artery; Humans; Infusions, Int

1979
Neutropenia associated with metronidazole.
    British medical journal, 1979, Nov-10, Volume: 2, Issue:6199

    Topics: Agranulocytosis; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Metronidazole;

1979
Combination chemotherapy of colorectal cancer with 5-fluorouracil, methyl-1,3-cis(2-chloroethyl)-1-nitrosourea, and vincristine.
    Medical and pediatric oncology, 1979, Volume: 7, Issue:3

    Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Fluoro

1979
[Preoperative irradiation of rectal carcinoma wit 5-fluorouracil].
    Strahlentherapie. Sonderbande, 1978, Volume: 75

    Topics: Adenocarcinoma; Cobalt Radioisotopes; Fluorouracil; Humans; Infusions, Parenteral; Preoperative Care

1978
Fluorouracil as an adjuvant to colorectal cancer surgery.
    JAMA, 1977, Feb-28, Volume: 237, Issue:9

    Topics: Adult; Aged; Colonic Neoplasms; Fluorouracil; Humans; Middle Aged; Postoperative Care; Rectal Neopla

1977
Fluorouracil and colorectal cancer.
    JAMA, 1977, Aug-08, Volume: 238, Issue:6

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Rectal Neoplasms; Solubility

1977
Lack of effectiveness of combined 5- fluorouracil and methyl-CCNU therapy in advanced colorectal cancer.
    Cancer, 1977, Volume: 40, Issue:6

    Topics: Carcinoembryonic Antigen; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans

1977
[Practice in the treatment of rectal carcinoma. Recommendations of the Deutschen Gesellschaft für Chirurgie].
    Medizinische Klinik, 1977, Dec-02, Volume: 72, Issue:48

    Topics: Anus Neoplasms; Female; Fluorouracil; Germany, West; Humans; Intestinal Polyps; Male; Neoplasm Metas

1977
Chemotherapy, immunotherapy and chemoimmunotherapy of colorectal cancer.
    Australasian radiology, 1977, Volume: 21, Issue:4

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Immunotherapy; Lomustine; Methotrexate; Mitomycins; Rectal

1977
Chemotherapy of colorectal cancer.
    Canadian journal of surgery. Journal canadien de chirurgie, 1978, Volume: 21, Issue:3

    Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Rectal Ne

1978
Multidisciplinary preoperative approach to the management of epidermoid carcinoma of the anus and anorectum.
    Diseases of the colon and rectum, 1978, Volume: 21, Issue:2

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Male; Middle Ag

1978
Sequential 5-fluorouracil and hydroxyurea therapy for metastatic colorectal adenocarcinoma.
    The Journal of the American Osteopathic Association, 1978, Volume: 77, Issue:8

    Topics: Adenocarcinoma; Colonic Neoplasms; Fluorouracil; Humans; Hydroxyurea; Neoplasm Metastasis; Rectal Ne

1978
Evaluation of single-agent therapy in human colorectal tumour xenografts.
    British journal of cancer, 1978, Volume: 37, Issue:5

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Mice; Neoplas

1978
Treatment of advanced colorectal cancer with a combination of 5-fluorouracil and methyl-CCNU.
    Medical and pediatric oncology, 1978, Volume: 4, Issue:3

    Topics: Adenocarcinoma; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Nitrosourea Comp

1978
Phase II study of melphalan in colorectal carcinoma.
    Cancer treatment reports, 1978, Volume: 62, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male;

1978
Combination of constant-infusion 5-fluorouracil, methyl-CCNU, mitomycin C, and vincristine in advanced colorectal carcinoma.
    Cancer treatment reports, 1978, Volume: 62, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; H

1978
Treatment of symptomatic metastatic cancer to the liver from primary colon and rectal cancer by the intraarterial administration of chemotherapy and radioactive isotopes.
    Journal of surgical oncology, 1978, Volume: 10, Issue:4

    Topics: Catheters, Indwelling; Colonic Neoplasms; Femoral Artery; Fluorouracil; Hepatic Artery; Humans; Infu

1978
Treatment of advanced colorectal cancer with methyl-CCNU plus 5-day 5-fluorouracil infusion.
    Cancer treatment reports, 1978, Volume: 62, Issue:10

    Topics: Adult; Aged; Bone Marrow Diseases; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Therapy, Combin

1978
Chemotherapy for colorectal cancer with a combination of 5-fluorouracil, mitomycin C, adriamycin, and cytosine arabinoside: a pilot study.
    Cancer treatment reports, 1978, Volume: 62, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Cytarabine; Doxorubicin; Drug Therapy, Com

1978
Cancer of the large bowel with special reference to incidence and etiology.
    The American surgeon, 1978, Volume: 44, Issue:9

    Topics: Carcinoembryonic Antigen; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Prognosis; Rectal N

1978
Ongoing trials in the surgical adjuvant management of colorectal cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Antineoplastic Agents; BCG Vaccine; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; F

1978
Multimodal surgical adjuvant therapy for a broad spectrum of tumors in humans.?
    Surgery, gynecology & obstetrics, 1976, Volume: 142, Issue:6

    Topics: Adult; Altretamine; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Carmustine; Colonic Neo

1976
Adjuvant treatment of colorectal cancer.
    The Western journal of medicine, 1977, Volume: 126, Issue:2

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Immunotherapy; Rectal Neoplasms

1977
Adjuvant treatment of cancer I. Large bowel cancer.
    Connecticut medicine, 1977, Volume: 41, Issue:5

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Immunity, Cellular; Immunotherapy; Rectal Neoplasms

1977
Adjuvant immunotherapy and chemoimmunotherapy in colorectal cancer (Dukes' class C): prolongation of disease-free interval and survival.
    Cancer, 1977, Volume: 40, Issue:5 Suppl

    Topics: BCG Vaccine; Carcinoma; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Neoplasm

1977
Gastrointestinal cancer. Treatment with fluorouracil-nitrosourea combinations.
    JAMA, 1976, May-10, Volume: 235, Issue:19

    Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neo

1976
Chemoprophylaxis for patients with colorectal cancer. Prospective study with five-year follow-up.
    JAMA, 1976, Jun-28, Volume: 235, Issue:26

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Follow-Up Stu

1976
Editorial: Progress in the treatment of colorectal cancer.
    JAMA, 1976, Jun-28, Volume: 235, Issue:26

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Neoplasm Metastasis; Postoperative Care; Rectal Neoplasms

1976
Editorial: Adjuvant chemotherapy in colorectal cancer.
    British medical journal, 1976, Aug-07, Volume: 2, Issue:6031

    Topics: Carcinoembryonic Antigen; Colonic Neoplasms; Fluorouracil; Neoplasm Metastasis; Rectal Neoplasms

1976
Fluorouracil as an adjuvant to colorectal cancer surgery; the breakthrough that never was.
    JAMA, 1976, Oct-25, Volume: 236, Issue:17

    Topics: Adult; Aged; Colonic Neoplasms; Fluorouracil; Humans; Middle Aged; Postoperative Care; Rectal Neopla

1976
Fluorouracil as an adjuvant to colorectal cancer surgery.
    JAMA, 1976, Nov-22, Volume: 236, Issue:21

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Postoperative Care; Rectal Neoplasms

1976
5-Fluorouracil (NSC-19893), DTIC (NSC-45388), BCNU (NSC-409962), and vincristine (NSC-67574) in advanced colorectal carcinoma.
    Cancer treatment reports, 1976, Volume: 60, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Dacarbazine; Drug Therapy, Combin

1976
[Late results of the prophylactic treatment with 5-fluorouracil of cancer of the large intestine and rectum].
    Klinicheskaia meditsina, 1976, Volume: 54, Issue:8

    Topics: Adult; Aged; Female; Fluorouracil; Follow-Up Studies; Humans; Intestinal Neoplasms; Intestine, Large

1976
5-Fluorouracil (5-FU), methyl-CCNU, and vincristine in the treatment of advanced colorectal cancer: phase II study utilizing weekly 5-FU.
    Cancer treatment reports, 1976, Volume: 60, Issue:11

    Topics: Adult; Aged; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combina

1976
Results of regional portal infusion of 5-fluorouracil in patients with primary and secondary liver cancer.
    Annales chirurgiae et gynaecologiae, 1976, Volume: 65, Issue:1

    Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Fluorouracil; Hepatic Artery; Humans; Infu

1976
Fluorouracil as an adjuvant to colorectal cancer surgery.
    JAMA, 1976, Nov-29, Volume: 236, Issue:22

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Neoplasm Metastasis; Postoperative Care; Rectal Neoplasms

1976
Survival among patients with liver metastases from cancer of the colon and rectum.
    Scandinavian journal of gastroenterology. Supplement, 1976, Volume: 37

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Colonic Neoplasms; F

1976
Immunotherapy of human solid tumors with Bacillus Calmette-Guérin: prolongation of disease-free interval and survival in malignant melanoma, breast, and colorectal cancer.
    Annals of the New York Academy of Sciences, 1976, Volume: 277, Issue:00

    Topics: BCG Vaccine; Breast Neoplasms; Colonic Neoplasms; Dacarbazine; Doxorubicin; Female; Fluorouracil; Hu

1976
Comparison of 5-fluorouracil with 5-fluorouracil, cyclophosphamide, and methotrexate in metastatic colorectal carcinoma.
    Cancer, 1975, Volume: 36, Issue:5

    Topics: Colonic Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouraci

1975
End results of radiation therapy, alone and combination with 5-fluorouracil in colorectal cancers.
    Cancer, 1975, Volume: 36, Issue:6

    Topics: Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Perineum; Radiotherapy; Radiothe

1975
Combined 5-fluorouracil and hydroxyurea therapy for gastrointestinal cancer.
    Oncology, 1975, Volume: 32, Issue:1

    Topics: Administration, Oral; Ataxia; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Gastrointe

1975
Arylsulfatse B in colorectal cancer.
    Cancer, 1975, Volume: 36, Issue:6 Suppl

    Topics: Adult; Aged; Chondro-4-Sulfatase; Colonic Neoplasms; Female; Fluorouracil; Humans; Isoenzymes; Male;

1975
Adjuvant immunotherapy and chemoimmunotherapy in colorectal cancer of the Dukes' C classification. Preliminary clinical results.
    Cancer, 1975, Volume: 36, Issue:6 Suppl

    Topics: BCG Vaccine; Carcinoembryonic Antigen; Colonic Neoplasms; Fluorouracil; Humans; Rectal Neoplasms

1975
The gasteointestinal oncology clinic. A multidisciplinary approach to cancer diagnosis and management at a University Medical Center.
    The Surgical clinics of North America, 1976, Volume: 56, Issue:1

    Topics: Adenocarcinoma; Colitis, Ulcerative; Colonic Neoplasms; Cyclophosphamide; Drug Therapy, Combination;

1976
Immunostimulation with intraperitoneally administered bacille Calmette Guérin for advanced malignant tumors of the gastrointestinal tract.
    Surgery, gynecology & obstetrics, 1976, Volume: 142, Issue:3

    Topics: Adult; Aged; BCG Vaccine; Bile Duct Neoplasms; Carcinoma; Colonic Neoplasms; Cyclophosphamide; Femal

1976
[Chemotherapy in gastrointestinal cancer].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Jan-30, Volume: 96, Issue:3

    Topics: Adult; Aged; Colonic Neoplasms; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Meth

1976
Editorial: Large-bowel cancer-The current status of treatment.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:1

    Topics: Adjuvants, Immunologic; BCG Vaccine; Carmustine; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combi

1976
Editorial: Large-bowel cancer-The current status of treatment.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:1

    Topics: Adjuvants, Immunologic; BCG Vaccine; Carmustine; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combi

1976
Editorial: Large-bowel cancer-The current status of treatment.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:1

    Topics: Adjuvants, Immunologic; BCG Vaccine; Carmustine; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combi

1976
Editorial: Large-bowel cancer-The current status of treatment.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:1

    Topics: Adjuvants, Immunologic; BCG Vaccine; Carmustine; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combi

1976
Current thoughts on the surgical treatment of rectal cancer.
    The American journal of gastroenterology, 1976, Volume: 65, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Fluorouracil;

1976
Intraarterial 5-FU-infusion and simultaneous radiotherapy as palliative treatment of recurrent rectal cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1992, Volume: 168, Issue:10

    Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Humans; Iliac Artery; Infusions, Intra

1992
Pattern of 2-deoxy-2-[18F]-fluro-D-glucose accumulation in liver tumours: primary, metastatic and after chemotherapy.
    Nuclear medicine communications, 1992, Volume: 13, Issue:3

    Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Colonic Neoplasms; Deoxyglucose; Fluorodeoxyglucose F18;

1992
[Cancers of the colon and the rectum: news in 1992].
    Pathologie-biologie, 1992, Volume: 40, Issue:9 Pt 2

    Topics: Amifostine; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusio

1992
Nonresectable adenocarcinoma of the rectum assessed by MR imaging before and after chemotherapy and irradiation.
    Acta radiologica (Stockholm, Sweden : 1987), 1992, Volume: 33, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

1992
The antitumor activity and immunosuppressive effects of 5-fluorouracil suppositories in rectal cancer patients.
    Surgery today, 1992, Volume: 22, Issue:3

    Topics: Aged; Female; Fluorouracil; Humans; Lymph Nodes; Lymphocyte Subsets; Male; Middle Aged; Premedicatio

1992
Advantages of the Papillon protocol in the preoperative treatment of rectal carcinoma.
    American journal of surgery, 1992, Volume: 164, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Protocols; Com

1992
A case of linitis plastica of the rectum treated by pelvic exenteration after aggressive immunochemotherapy.
    Surgery today, 1992, Volume: 22, Issue:2

    Topics: Adult; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Injections, Intra

1992
Adjuvant chemotherapy and radiotherapy in the management of colorectal cancer.
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:8 Suppl

    Topics: Chemotherapy, Adjuvant; Colonic Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Mal

1992
[Neo-adjuvant chemotherapy with tegafur suppository for rectal cancer--evaluation of the antitumor effects, tissue levels of 5-FU and inhibition of thymidylate synthase. Tochigi Colorectal Cancer Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:11

    Topics: Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Male; Rectal Neoplasms; Suppositories; Tegafur

1992
Adjuvant postoperative radiation therapy for rectal adenocarcinoma.
    American journal of clinical oncology, 1992, Volume: 15, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Female; Fluorouracil; Fol

1992
[Continuous intra-arterial infusion chemotherapy in colorectal cancer patients with nonresectable metastatic liver cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl

    Topics: Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Infusion Pumps; Infusions, In

1992
Mitomycin C, 5-fluorouracil and radiation in advanced, locally recurrent rectal cancer.
    The British journal of radiology, 1992, Volume: 65, Issue:770

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

1992
Combined modality preoperative therapy for unresectable rectal cancer.
    Connecticut medicine, 1992, Volume: 56, Issue:1

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fem

1992
[Indication for chemoembolization of liver tumors. An interdisciplinary concept and initial results].
    Der Radiologe, 1992, Volume: 32, Issue:2

    Topics: Adult; Chemoembolization, Therapeutic; Colonic Neoplasms; Female; Fluorouracil; Germany, West; Human

1992
[A case report of complete remission of liver metastasis from rectal carcinoma treated with intra-arterial infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Infusion

1992
Combined modality adjuvant treatment of high-risk rectal cancer: a treatment of choice or a choice of treatment?
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy;

1992
High-dose folinic acid, 5-fluorouracil bolus and continuous infusion in metastatic colorectal cancer: a 3-day/3-week schedule. Group d'Etude et de Recherche sur les Cancers de l'Ovaire et Digestifs (GERCOD)
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28, Issue:2-3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; F

1992
Levamisole plus 5-fluorouracil inhibits the growth of human colorectal xenografts in nude mice.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:6-7

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorour

1992
Preliminary evidence that incorporation of 5-fluorouracil into RNA correlates with antitumor response.
    Cancer investigation, 1992, Volume: 10, Issue:4

    Topics: Colonic Neoplasms; Fluorodeoxyuridylate; Fluorouracil; Humans; Liver Neoplasms; Rectal Neoplasms; Re

1992
A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa.
    Cancer, 1991, Nov-01, Volume: 68, Issue:9

    Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Colon; Colonic Neoplasms; Fluorodeoxyuridylate; Flu

1991
Enhancement of radiation-induced downstaging of rectal cancer by fluorouracil and high-dose leucovorin chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

1992
Preoperative radiation therapy for locally advanced carcinoma of the rectum. Clinicopathologic correlative review.
    Diseases of the colon and rectum, 1992, Volume: 35, Issue:1

    Topics: Adenocarcinoma; Combined Modality Therapy; Fluorouracil; Humans; Lymphatic Metastasis; Neoplasm Stag

1992
[Studies on a slow releasing anticancer agent for prevention of peritoneal recurrence of advanced gastrointestinal carcinomas (clinical study)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:2

    Topics: Delayed-Action Preparations; Duodenal Neoplasms; Fluorouracil; Humans; Infusions, Parenteral; Lactat

1992
[Adjuvant treatment of resected colon cancers using a 5-fluorouracil-levamisole combination].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:8-9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Fluoro

1991
Effect of leucovorin on 5-fluorouracil induced inhibition of thymidylate synthase in patients with colon cancer.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Leu

1991
[Myocardial damage after use of 5 fluorouracil in digestive pathology].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:10

    Topics: Aged; Fluorouracil; Humans; Male; Myocardial Infarction; Rectal Neoplasms

1991
The effects of gamma-interferon combined with 5-fluorouracil or 5-fluoro-2'-deoxyuridine on proliferation and antigen expression in a panel of human colorectal cancer cell lines.
    International journal of cancer, 1991, Jul-09, Volume: 48, Issue:5

    Topics: Antibodies, Monoclonal; Carcinoembryonic Antigen; Cell Division; Cell Line; Colonic Neoplasms; Drug

1991
Clinical trials referral resource. Adjuvant therapy for rectal cancer.
    Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy;

1991
Prognostic factors in patients with liver metastases from colorectal carcinoma treated with discontinuous intra-arterial hepatic chemotherapy.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Female; Fluorouracil; Gastrointestinal Diseases; Hep

1991
[Evaluation of continuous intra-arterial infusion chemotherapy after hepatic resection of liver metastases in colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil;

1991
[Interstitial hyperthermia (MINERVE) for perineal local recurrence of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Cispl

1991
Cancer-associated hemolytic-uremic syndrome with spontaneous resolution. A case report.
    Tumori, 1991, Apr-30, Volume: 77, Issue:2

    Topics: Antineoplastic Agents; Female; Fluorouracil; Hemolytic-Uremic Syndrome; Humans; Middle Aged; Mitomyc

1991
Disappearance of hyperplastic polyposis after resection of rectal cancer. Report of two cases.
    Diseases of the colon and rectum, 1991, Volume: 34, Issue:9

    Topics: Adenocarcinoma; Aged; Anastomosis, Surgical; Brachytherapy; Colonic Neoplasms; Colonoscopy; Combined

1991
Combined radiation therapy, mitomycin C, and 5-fluorouracil for locally recurrent rectal carcinoma: results of a pilot study.
    International journal of radiation oncology, biology, physics, 1991, Volume: 21, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

1991
Sphincter preservation in rectal cancer by local excision and postoperative radiation therapy.
    Cancer, 1991, Feb-15, Volume: 67, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Brachytherapy; Combined Modality Therapy; Female; Fluoroura

1991
Combined-modality therapy for rectal carcinoma--the time has come.
    The New England journal of medicine, 1991, Mar-14, Volume: 324, Issue:11

    Topics: Adenocarcinoma; Combined Modality Therapy; Fluorouracil; Humans; Neoplasm Recurrence, Local; Rectal

1991
Preoperative high-dose leucovorin/5-fluorouracil and radiation therapy for unresectable rectal cancer.
    Cancer, 1991, Jun-01, Volume: 67, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combined Modality Therapy; Fluorourac

1991
A pilot study of sphincter-sparing management of adenocarcinoma of the rectum.
    Archives of surgery (Chicago, Ill. : 1960), 1991, Volume: 126, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Combined Modality Therapy; Female; Fluorouracil; Humans; Ma

1991
[Treatment of colorectal cancers. Recommendations of the French Foundation of Digestive Cancerology].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Digestive System Neoplasms; Fluor

1991
[Intra-arterial chemotherapy in inoperable and recurrent rectal tumors].
    Bratislavske lekarske listy, 1990, Volume: 91, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Injections, Intr

1990
Oral carmofur in advanced gastrointestinal cancer.
    American journal of clinical oncology, 1990, Volume: 13, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Admini

1990
[Adjuvant treatment of colon and rectum carcinoma: one step ahead].
    Nederlands tijdschrift voor geneeskunde, 1990, Dec-01, Volume: 134, Issue:48

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Fluorou

1990
Tumor trapping of 5-fluorouracil: in vivo 19F NMR spectroscopic pharmacokinetics in tumor-bearing humans and rabbits.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic N

1990
[Clinical reevaluation of continuous intravenous infusion of 5-fluorouracil--plasma concentrations and clinical dose by continuous intravenous and 60-min infusions].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:2

    Topics: Adult; Aged; Drug Administration Schedule; Evaluation Studies as Topic; Female; Fluorouracil; Humans

1990
A new catheter to simplify portal vein cannulation for adjuvant cytotoxic liver perfusion following resection of rectal cancer.
    British journal of cancer, 1990, Volume: 61, Issue:5

    Topics: Catheterization, Peripheral; Combined Modality Therapy; Fluorouracil; Humans; Portal Vein; Postopera

1990
[Current status of chemotherapy for colonic, rectal and anal carcinoma].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1990, Jul-17, Volume: 79, Issue:29-30

    Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Colonic Neoplasms; Combi

1990
[Chemotherapy and total body hyperthermia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Colonic Neoplasms; Combined Mo

1985
Unresectable and locally recurrent rectal cancer treated with radiotherapy or bilateral internal iliac artery infusion of 5-fluorouracil.
    Cancer, 1986, Jul-15, Volume: 58, Issue:2

    Topics: Adult; Aged; Fluorouracil; Humans; Iliac Artery; Infusions, Intra-Arterial; Middle Aged; Neoplasm Re

1986
External beam radiotherapy for rectal adenocarcinoma.
    The British journal of surgery, 1987, Volume: 74, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle A

1987
5-Fluorouracil and isoprinosine in the treatment of advanced colorectal cancer. A limited phase I, II evaluation.
    Cancer, 1988, Sep-15, Volume: 62, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Female; Fl

1988
Continuous low-dose infusion of fluorouracil: is the benefit worth the cost?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:4

    Topics: Colonic Neoplasms; Cost-Benefit Analysis; Fluorouracil; Humans; Infusions, Intravenous; Injections,

1989
Postoperative adjuvant chemotherapy and radiotherapy for cancer of the large bowel and rectum.
    American journal of surgery, 1989, Volume: 157, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cecal Neoplasms; Colonic Neop

1989
Phase I and II studies of the combination of recombinant human interferon-gamma and 5-fluorouracil in patients with advanced colorectal carcinoma.
    Journal of biological response modifiers, 1989, Volume: 8, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neop

1989
Preoperative irradiation with and without chemotherapy (MFL) in the treatment of primarily non-resectable adenocarcinoma of the rectum. Results from two consecutive studies.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

1989
Local chemotherapy for rectal polyposis: intraluminal administration of 5-fluorouracil for postoperative control of adenomas in the retained rectum in familial polyposis.
    Journal of clinical gastroenterology, 1989, Volume: 11, Issue:6

    Topics: Adenomatous Polyposis Coli; Administration, Rectal; Adult; Colectomy; Combined Modality Therapy; Ene

1989
Adjuvant therapy for rectal cancer: is 5-FU effective without MeCCNU.
    Oncology (Williston Park, N.Y.), 1989, Volume: 3, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Rectal Neoplasms; Semustine

1989
Radiation therapy with/without simultaneous weekly 5 F.U. in locally recurrent carcinoma of the recto-sigmoid.
    The West Virginia medical journal, 1989, Volume: 85, Issue:4

    Topics: Adenocarcinoma; Combined Modality Therapy; Fluorouracil; Humans; Neoplasm Recurrence, Local; Rectal

1989
Immunochemotherapy of advanced colorectal cancer with alpha-interferon and 5-fluorouracil. 1. Toxicological studies.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil

1989
5-Fluorouracil-induced angina.
    The Journal of the Oklahoma State Medical Association, 1989, Volume: 82, Issue:8

    Topics: Aged; Angina Pectoris; Coronary Vasospasm; Female; Fluorouracil; Humans; Liver Neoplasms; Platelet A

1989
Biological features and chemosensitivity of human colorectal cancer xenografted in nude mice.
    Gastroenterologia Japonica, 1987, Volume: 22, Issue:5

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Antineoplastic Agents; Carcinoembryonic Antigen;

1987
Perianal Paget's disease. Report of three cases.
    Diseases of the colon and rectum, 1988, Volume: 31, Issue:6

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anus Neoplasms; Female; Fluorouracil; Humans; Male; Neoplas

1988
Hepatic artery infusion chemotherapy for colorectal metastases: a personal experience.
    Journal of surgical oncology, 1985, Volume: 30, Issue:3

    Topics: Adult; Aged; Carcinoma; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans

1985
Incorporation of intermediary products of 5-FU anabolism into colorectal cancer.
    Gut, 1986, Volume: 27, Issue:2

    Topics: Aged; Colon; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Humans; Intestinal Mucosa; Male;

1986
Implantable vascular access devices in the treatment of colorectal liver metastases.
    The British journal of surgery, 1986, Volume: 73, Issue:6

    Topics: Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arter

1986
Comparison of 5-FU versus FUDR activity in human colorectal cancer using an in vitro clonogenic assay (HTCA).
    Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:3

    Topics: Colonic Neoplasms; Colony-Forming Units Assay; Culture Techniques; Dose-Response Relationship, Drug;

1986
[Chemoprophylaxis of liver metastasis of colonic and rectal cancers].
    Presse medicale (Paris, France : 1983), 1986, Sep-13, Volume: 15, Issue:29

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Liver Neoplasms; Neoplasm Metastasis; Portal Vein; Rectal N

1986
The relationship between plasma pharmacokinetics and tissue metabolites of 5-fluorouracil (5-FU) in patients with colorectal cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1987, Volume: 13, Issue:4

    Topics: Aged; Aged, 80 and over; Colon; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Humans; Kineti

1987
Regional and systemic chemotherapy for colorectal metastases to the liver.
    World journal of surgery, 1987, Volume: 11, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridine; Fluorouracil; Humans

1987
[Locoregional chemotherapy of hepatic metastases of colorectal cancer].
    Annales de gastroenterologie et d'hepatologie, 1987, Volume: 23, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; Infusion Pumps; I

1987
Concentration and time dependence of the toxicity of fluorinated pyrimidines to HT 29 colorectal carcinoma cells.
    Cancer chemotherapy and pharmacology, 1988, Volume: 22, Issue:1

    Topics: Cell Line; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Floxuridine; Fluorour

1988
Doxifluridine (5'-dFUrd) in patients with advanced colorectal carcinoma. A phase II study.
    Cancer chemotherapy and pharmacology, 1985, Volume: 15, Issue:2

    Topics: Angina Pectoris; Brain Diseases; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Evaluation; Elect

1985
Palliation of pelvic recurrence of colorectal cancer with intra-arterial 5-fluorouracil and mitomycin.
    Cancer, 1985, Nov-01, Volume: 56, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; C

1985
Radiolabeled antibody in the treatment of primary and metastatic liver malignancies.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1986, Volume: 100

    Topics: Animals; Antibodies; Biliary Tract Neoplasms; Carcinoembryonic Antigen; Carcinoma, Hepatocellular; C

1986
[Combination chemotherapy of cis-diamminedichloroplatinum (CDDP) and 5-fluorouracil (5-FU) in gastrointestinal tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; C

1986
[Angiographic and computed tomographic findings in intra-arterial cytostasis of colorectal liver metastases].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1986, Volume: 145, Issue:4

    Topics: Angiography; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Intra-Arteri

1986
Treatment of metastatic colorectal cancer with hepatic artery combination chemotherapy.
    Cancer, 1986, Mar-15, Volume: 57, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Fluorouracil; Follow-

1986
Combination chemotherapy for advanced colorectal cancer. A pilot study.
    American journal of clinical oncology, 1986, Volume: 9, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Female; F

1986
Combined preoperative neoadjuvant radiotherapy and chemotherapy for anal and rectal cancer.
    American journal of surgery, 1986, Volume: 151, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squ

1986
Squamous cell carcinoma of the rectum: a multimodality approach.
    Journal of surgical oncology, 1986, Volume: 32, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy;

1986
Clinical evidence of feasibility and efficacy of simultaneous irradiation and chemotherapy in advanced squamous cell carcinoma.
    Progress in clinical and biological research, 1986, Volume: 216

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brachytherapy; Carcinom

1986
An aggressive, sequential combination chemotherapy regimen in the treatment of metastatic colorectal carcinoma.
    Progress in clinical and biological research, 1986, Volume: 216

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dose-Response Relati

1986
The efficacy of 5-fluorouracil, mitomycin C, and methyl CCNU in advanced colorectal cancer.
    American journal of clinical oncology, 1986, Volume: 9, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Flu

1986
[Surgery and adjuvant therapy of cancer of the large intestine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:7

    Topics: BCG Vaccine; Colonic Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule

1986
[5-FU concentration in the blood and tissue of patients with gastric and colorectal cancer after administration of UFT or tegafur].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Male; Rats

1986
Intraarterial chemotherapy and hyperthermia for pain control in patients with recurrent rectal cancer.
    American journal of surgery, 1986, Volume: 152, Issue:6

    Topics: Aged; Female; Fluorouracil; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Male; Middle A

1986
Rationale and indications for perfusion in liver tumors: current data.
    World journal of surgery, 1987, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusio

1987
[Serum concentration of 5-FU and tegafur (FT-207) after administration of tegafur (FT-207) suppository with the colostomy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:10

    Topics: Adult; Aged; Colostomy; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged;

1987
[Human colorectal carcinoma is more sensitive to HCFU than 5-FU and tegafur in in vitro and in vivo drug sensitivity tests].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:2

    Topics: Animals; Colonic Neoplasms; Fluorouracil; Humans; Mice; Rectal Neoplasms; Subrenal Capsule Assay; Te

1988
[Antitumor effect of intermittent oral administration of UFT against human rectal cancer xenografted in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Drug Adm

1988
Phase II study of a 5-fluorouracil, teniposide and mitomycin-C combination chemotherapy in advanced colorectal carcinomas.
    Tumori, 1988, Feb-29, Volume: 74, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Colonic Neoplasms; Diarrhea; D

1988
[Intra-arterial chemotherapy of colorectal liver metastases with 5-fluorouracil (5-FU) and mitomycin C (MMC)].
    Helvetica chirurgica acta, 1987, Volume: 54, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil

1987
Colorectal carcinoma in vitro is more sensitive to 1-hexylcarbamoyl-5-fluorouracil compared with six other antitumor drugs: carboquone, Adriamycin, mitomycin C, aclacinomycin A, cisplatin, 5-fluorouracil.
    Diseases of the colon and rectum, 1988, Volume: 31, Issue:1

    Topics: Aclarubicin; Antineoplastic Agents; Carbazilquinone; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug

1988
[The serum and tissue concentrations of tegafur, 5-fluorouracil and uracil in patients with gastric and colorectal cancers after oral administration of UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouraci

1988
[Results of intra-arterial infusion chemotherapy in colorectal cancer patients with metastatic liver cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cholestasis; Colonic Neoplasms; Combined Modality Th

1988
Combined modality preoperative therapy in poor prognostic rectal adenocarcinoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1988, Volume: 13, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb

1988
Treatment of colorectal cancer hepatic metastases by hepatic artery chemotherapy.
    Diseases of the colon and rectum, 1985, Volume: 28, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Floxuridine; Fluorour

1985
The efficacy of 5-fluorouracil in human colorectal cancer is not enhanced by thymidylate synthetase inhibition with CB3717 (N10-propargyl-5,8 dideazafolic acid).
    British journal of cancer, 1988, Volume: 58, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluo

1988
[Continuous infusion of anti-cancer drug with balloon infusors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:11

    Topics: Aged; Breast Neoplasms; Colonic Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Humans

1988
Postoperative radiation therapy with weekly 5 fluorouracil.
    The West Virginia medical journal, 1988, Volume: 84, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Female; Fluorouracil; Hum

1988
[Route and preparation of 5-Fu administration as preoperative adjuvant chemotherapy in rectal cancer. I. Concentration and distribution of 5-Fu in tissues monitored by 14C-isotopically tagged 5-Fu].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1988, Volume: 10, Issue:2

    Topics: Absorption; Administration, Rectal; Animals; Carbon Radioisotopes; Emulsions; Fluorouracil; Humans;

1988
[Route and preparation of 5-Fu administration as preoperative adjuvant chemotherapy in rectal cancer. II. Morphologic, ultrastructural and histochemical changes of the cancer cells after intrarectal and intravenous 5-Fu administration].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1988, Volume: 10, Issue:3

    Topics: Administration, Rectal; DNA, Neoplasm; Emulsions; Fluorouracil; Humans; Premedication; Rectal Neopla

1988
[Intra-arterial 5-fluorouracil chemotherapy in liver metastases of colorectal cancer].
    Medizinische Klinik (Munich, Germany : 1983), 1988, Oct-28, Volume: 83, Issue:21

    Topics: Adult; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Infusion Pumps; Infusions, Intra-Arter

1988
Treatment of advanced-stage colorectal adenocarcinoma with fluorouracil and high-dose leucovorin calcium: a pilot study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administrati

1988
Continuous infusion 5-fluorouracil and folinic acid in disseminated colorectal cancer.
    Cancer investigation, 1988, Volume: 6, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug

1988
High-dose folinic acid and 5-fluorouracil in advanced colorectal cancer.
    Cancer investigation, 1988, Volume: 6, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Gastr

1988
Plasma and tumor tissue pharmacology of high-dose intravenous leucovorin calcium in combination with fluorouracil in patients with advanced colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Colonic Neopla

1988
Pharmacodynamics of 5-fluorouracil and leucovorin.
    Advances in experimental medicine and biology, 1988, Volume: 244

    Topics: Adenocarcinoma; Animals; Bone Marrow; Colonic Neoplasms; Deoxyuracil Nucleotides; Fluorodeoxyuridyla

1988
Phase II evaluation of sequential hepatic artery infusion of 5-fluorouracil and hepatic irradiation in metastatic colorectal carcinoma.
    Journal of surgical oncology, 1988, Volume: 37, Issue:1

    Topics: Colonic Neoplasms; Combined Modality Therapy; Drug Evaluation; Female; Fluorouracil; Humans; Infusio

1988
Colorectal carcinoma in patients younger than 40 years of age. Montpellier Cancer Institute experience with 78 patients.
    Cancer, 1988, Feb-15, Volume: 61, Issue:4

    Topics: Adenocarcinoma; Adult; Age Factors; Colonic Neoplasms; Female; Fluorouracil; France; Humans; Male; R

1988
[Prevention of immunodeficiency induced by cancer chemotherapy with BCG].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Colonic Neoplasms; Cytarabine; Fe

1988
[Studies of 5-FU concentrations associated with microangiography in colorectal cancer tissue].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:2

    Topics: Adult; Aged; Angiography; Colonic Neoplasms; DNA, Neoplasm; Female; Fluorouracil; Humans; Male; Midd

1988
Intraperitoneal infusion of 5-FU in liver metastases from colorectal cancer.
    Journal of surgical oncology, 1988, Volume: 37, Issue:2

    Topics: Abdomen; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Infusion Pumps; Liver Neoplasms; Mal

1988
[Preliminary results of preoperative regional chemotherapy of cancer of the rectum].
    Voprosy onkologii, 1988, Volume: 34, Issue:2

    Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Mal

1988
Pharmacokinetics and pharmacodynamics of locoregional 5 fluorouracil (5FU) in advanced colorectal liver metastases.
    British journal of cancer, 1988, Volume: 57, Issue:2

    Topics: Albumins; Angiotensin II; Colonic Neoplasms; Fluorouracil; Hepatic Artery; Humans; Injections, Intra

1988
Colorectal cancer chemotherapy: meta-analysis or large-scale trials?
    JAMA, 1988, Jun-24, Volume: 259, Issue:24

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Rectal

1988
Hypotension as a manifestation of cardiotoxicity in three patients receiving cisplatin and 5-fluorouracil.
    Cancer, 1988, Jul-15, Volume: 62, Issue:2

    Topics: Adult; Cisplatin; Colonic Neoplasms; Echocardiography; Electrocardiography; Female; Fluorouracil; He

1988
Preoperative irradiation and 5-fluorouracil suppository for carcinoma of the rectum.
    American journal of surgery, 1988, Volume: 156, Issue:1

    Topics: Aged; Combined Modality Therapy; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Neop

1988
Hepatic arterial ligation with and without portal infusion in metastatic colorectal cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 110

    Topics: Adult; Aged; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Hepatic Artery; Hum

1988
[Transcatheter arterial chemoembolization and selective hepatic arterial infusion using totally implantable reservoir].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Embolization, Therap

1988
Intra-hepato-arterial chemotherapy with CDDP and 5-FU for metastases to the liver from colorectal and gastric cancers.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Admi

1988
Advanced colorectal carcinoma--5 year survival of 76 cases treated at the Department of Therapeutic Radiology, Singapore General Hospital.
    Annals of the Academy of Medicine, Singapore, 1987, Volume: 16, Issue:3

    Topics: Actuarial Analysis; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma; Colonic Neoplasms; Co

1987
Sensitivity of newly established colorectal cell lines to cytotoxic drugs and monoclonal antibody drug conjugates.
    British journal of cancer, 1987, Volume: 56, Issue:6

    Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Agents; Cell Survival; Colonic Neoplasms;

1987
A new technique for hepatic infusional chemotherapy.
    Seminars in surgical oncology, 1986, Volume: 2, Issue:2

    Topics: Catheterization, Peripheral; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Intra-Arterial; Liv

1986
Principia of cancer therapy. XIX. Effects of per rectum carmofur on radiotherapeutic efficacy of rectal carcinomas.
    The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku, 1987, Volume: 34, Issue:1-4

    Topics: Carcinoembryonic Antigen; Carcinoma; Fluorouracil; Humans; Metabolic Clearance Rate; Rectal Neoplasm

1987
[Prevention of hepatic metastasis in patients operated on for colorectal carcinoma].
    Minerva chirurgica, 1987, Jun-30, Volume: 42, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Epirubicin; Fluorour

1987
Sequential methotrexate--5-FU--leucovorin (MFL) in advanced colorectal cancer.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration

1986
High-dose continuous infusion folinic acid and bolus 5-fluorouracil in patients with advanced colorectal cancer: a phase II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Fem

1986
[Chemotherapy of advanced and recurrent colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:7

    Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality

1986
Sequential methotrexate, 5-fluorouracil, and calcium leucovorin in colorectal carcinoma.
    American journal of clinical oncology, 1986, Volume: 9, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fema

1986
Continuous 5-fluorouracil infusion and pulse methotrexate/leucovorin for colorectal adenocarcinoma. A report of excessive toxicity.
    American journal of clinical oncology, 1987, Volume: 10, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; C

1987
Severe and fatal toxic effects observed in treatment with high- and low-dose leucovorin plus 5-fluorouracil for colorectal carcinoma.
    Cancer treatment reports, 1987, Volume: 71, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea

1987
High-dose folinic acid (HDFA) combined with 5-fluorouracil (5-FU) in first line chemotherapy of advanced large bowel cancer.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Female; Fl

1987
Sequential 5-fluorouracil and methotrexate. Negative experience in metastatic colorectal cancer.
    Acta oncologica (Stockholm, Sweden), 1987, Volume: 26, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Fem

1987
Biologic modulation of 5-fluorouracil with high-dose leucovorin and combination chemotherapy of 5-fluorouracil and cisplatin in metastatic colorectal adenocarcinoma.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Dose-R

1987
Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Gas

1987
[Whole-body hyperthermia and hyperglycemia in the combined treatment of rectal cancer].
    Meditsinskaia radiologiia, 1987, Volume: 32, Issue:1

    Topics: Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Glucose; Humans; Hyperglycemia; Hyperthe

1987
[Response to hepatic intra-arterial chemotherapy for metastases of colorectal cancer. Anatomo-pathological evaluation apropos of 3 cases of secondary hepatic excision].
    Gastroenterologie clinique et biologique, 1987, Volume: 11, Issue:1

    Topics: Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intra-Arteria

1987
Cannulation of the portal vein for cytotoxic liver perfusion in colorectal carcinomas: an alternative approach.
    Annals of the Royal College of Surgeons of England, 1987, Volume: 69, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Catheterization; Colonic Neoplasms; Fluorouracil; Humans; Liv

1987
Early adjuvant intraportal chemotherapy after curative hepatectomy for colorectal liver metastases--a pilot study.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1987, Volume: 13, Issue:3

    Topics: Adenocarcinoma; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Hepatectomy; Humans; Inf

1987
[Sequential methotrexate-5-fluorouracil (MTX-5-FU) treatment of patients with advanced gastric and colorectal cancer. Sequential Methotrexate-5-FU Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:8

    Topics: Adult; Aged; Colonic Neoplasms; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female;

1987
[The effect and CT imaging of FAM hepatic infusion chemotherapy in patients with liver metastasis from colorectal carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Female; Fluorouracil

1987
Treatment modalities for colorectal cancer.
    Seminars in oncology nursing, 1986, Volume: 2, Issue:4

    Topics: Colonic Neoplasms; Colostomy; Combined Modality Therapy; Fluorouracil; Humans; Rectal Neoplasms

1986
Cisplatin and 5-fluorouracil combination chemotherapy in advanced and/or metastatic colorectal carcinoma: a phase II study.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neop

1987
Hyperthermic pelvic isolation-perfusion in the treatment of refractory pelvic cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1987, Volume: 122, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Fe

1987
Tumor and liver drug uptake following hepatic artery and portal vein infusion.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:11

    Topics: Aged; Colonic Neoplasms; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; In

1987
[Continuous intra-arterial infusion chemotherapy by implantable catheter access connected with a continuous infusion pump].
    Gan no rinsho. Japan journal of cancer clinics, 1987, Volume: 33, Issue:12

    Topics: Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Infusion Pumps; Infusions, Intra-Arterial; In

1987
[Angina pectoris during regional chemotherapy of liver metastases].
    Deutsche medizinische Wochenschrift (1946), 1987, Dec-18, Volume: 112, Issue:51-52

    Topics: Angina Pectoris; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Rectal Neoplasms

1987
Combination chemotherapy of cisplatin and 5-FU in advanced colorectal carcinoma.
    Cancer treatment reports, 1986, Volume: 70, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Eval

1986
Ambulatory hepatic artery infusion chemotherapy for cancer of the liver.
    American journal of surgery, 1986, Volume: 151, Issue:5

    Topics: Adult; Aged; Ambulatory Care; Catheters, Indwelling; Colonic Neoplasms; Female; Fluorouracil; Gastro

1986
Determinants of survival after intraarterial infusion of 5-fluorouracil for liver metastases from colorectal cancer: a multivariate analysis.
    Journal of surgical oncology, 1986, Volume: 31, Issue:4

    Topics: Adult; Aged; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusion

1986
Failure of allopurinol to provide clinically significant protection against the hematologic toxicity of a bolus 5-FU schedule.
    Oncology, 1986, Volume: 43, Issue:4

    Topics: Adenocarcinoma; Adult; Allopurinol; Carcinoma, Squamous Cell; Colonic Neoplasms; Drug Administration

1986
Phase II-study vindesine + 5-Fluoro-Uracil combination chemotherapy in advanced colorectal cancer.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Hu

1986
Chemotherapy with or without anticoagulation as initial management of patients with operable colorectal cancer: a prospective study with at least 5 years follow-up.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1986, Volume: 103

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Fluoro

1986
[Early adjuvant intraportal chemotherapy after hepatectomy for metastases of colorectal origin].
    Journal de chirurgie, 1986, Volume: 123, Issue:5

    Topics: Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Hepatectomy; Humans; Infusions, Parenter

1986
Phase II study of hepatic artery infusion with 5-fluorouracil, adriamycin, and mitomycin C (FAM) in liver metastases from colorectal carcinoma.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1986, Volume: 100

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Drug Ev

1986
Chemotherapy in colorectal cancer.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1986, Volume: 5, Issue:5

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neo

1986
Treatment of advanced colorectal and gastric cancer with cisplatinum and 5-fluorouracil. A pilot study.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1986, Volume: 5, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Female; F

1986
5-Fluorouracil-metronidazole combination therapy in metastatic colorectal cancer. Clinical, pharmacokinetic and in vitro cytotoxicity studies.
    Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Colonic Neoplasms; Femal

1986
Response of colo-rectal hepatic metastases to concomitant radiotherapy and intravenous infusion 5 fluorouracil.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil;

1986
[Successful cure of rectal cancer by conservative methods (a case report)].
    Voprosy onkologii, 1987, Volume: 33, Issue:1

    Topics: Aged; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Humans; Male; Rectal Neoplasms; Re

1987
Weekly 5-fluorouracil combined with PALA: toxic and therapeutic effects in colorectal cancer.
    Cancer treatment reports, 1987, Volume: 71, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Central Nervous System D

1987
Thymidylate synthase gene amplification in a colon tumor resistant to fluoropyrimidine chemotherapy.
    Cancer treatment reports, 1987, Volume: 71, Issue:3

    Topics: Colonic Neoplasms; DNA, Neoplasm; Drug Resistance; Fluorouracil; Gene Amplification; Humans; Male; M

1987
Colorectal cancer (Duke's group B2, C1, C2): adjuvant chemotherapy and toxicity.
    The Mount Sinai journal of medicine, New York, 1985, Volume: 52, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chemical and Drug Induced

1985
Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil combined with high-dose folinic acid. An update.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1985, Volume: 4, Issue:5

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fl

1985
Selective modulation of 5-fluorouracil action in patients with colorectal carcinoma.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1985, Volume: 4, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Humans; Ki

1985
Preoperative radiation therapy with sensitizers in the management of carcinoma of the rectum.
    Diseases of the colon and rectum, 1985, Volume: 28, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Mit

1985
Long-term survivors of colorectal cancer with unresectable hepatic metastases.
    Diseases of the colon and rectum, 1985, Volume: 28, Issue:8

    Topics: Administration, Oral; Aged; Carcinoembryonic Antigen; Colonic Neoplasms; Female; Fluorouracil; Human

1985
[Colony assay for clinical application].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:8

    Topics: Adult; Agar; Aged; Antineoplastic Agents; Cell Count; Cell Division; Cells, Cultured; Colonic Neopla

1985
The use of radiation therapy combined with chemotherapy in the management of squamous cell carcinoma of the anus and marginally resectable adenocarcinoma of the rectum.
    International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:9

    Topics: Aged; Antibiotics, Antineoplastic; Anus Neoplasms; Carcinoma, Squamous Cell; Combined Modality Thera

1985
Anorectal squamous cell carcinoma at Mississippi Baptist Medical Center: results of the last five years of the Nigro schedule.
    Journal of the Mississippi State Medical Association, 1985, Volume: 26, Issue:10

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; C

1985
[Multimodality therapy of colorectal cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:9 Suppl

    Topics: Aged; Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Administration Schedule; Emboliz

1985
Long-term ambulatory treatment of metastatic colorectal adenocarcinoma by continuous intravenous infusion of 5-fluorouracil.
    Journal of surgical oncology, 1985, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Ambulatory Care; Colonic Neoplasms; Female; Fluorouracil; Humans; Infus

1985
Sequential therapy with methotrexate and 5-fluorouracil in the treatment of advanced colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:1

    Topics: Adult; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neopl

1986
Methyl-CCNU and methotrexate therapy in patients with advanced colorectal cancer after failure of 5-fluorouracil chemotherapy.
    American journal of clinical oncology, 1986, Volume: 9, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil

1986
[Distribution of 1-hexycarbamoyl-5-fluorouracil in rats and human patients, and clinical results in patients with colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Humans; Mal

1986
Phase II study of sequential methotrexate and 5-FU combination in the treatment of advanced colorectal cancer.
    Cancer treatment reports, 1986, Volume: 70, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Flu

1986
[Adjuvant chemotherapy in colorectal carcinoma].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1985, Volume: 64, Issue:1

    Topics: Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Rectal Neoplasms

1985
[Preoperative treatment with 5-fluorouracil (5-FU) in gastric and colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:2

    Topics: Administration, Oral; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Parenteral; Injections, In

1985
Hepatic resection of colorectal metastases. Influence of clinical factors and adjuvant intraperitoneal 5-fluorouracil via Tenckhoff catheter on survival.
    Annals of surgery, 1985, Volume: 201, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Carcinoembryonic Antigen; Colonic Neoplasms; Combined Modal

1985
Phase I evaluation and pharmacokinetic study of weekly iv thymidine and 5-FU in patients with advanced colorectal carcinoma.
    Cancer treatment reports, 1985, Volume: 69, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration

1985
[Chemotherapy protocol for metastasizing colorectal carcinoma. Methotrexate, 5-fluorouracil and cytarabine].
    Deutsche medizinische Wochenschrift (1946), 1985, Mar-29, Volume: 110, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cytarabine; Drug Adm

1985
[Therapy-induced tumor regression. Morphological findings in malignant primary and secondary liver tumors following intensive regional cytostatic treatment].
    Der Pathologe, 1985, Volume: 6, Issue:1

    Topics: Adenocarcinoma; Carcinoid Tumor; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Doxoru

1985
[Radiotherapy. Locally advanced colorectal cancer with and without 5-fluorouracil].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1985, Feb-28, Volume: 105, Issue:6

    Topics: Aged; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged;

1985
[Risk-related surgical treatment of colorectal tumors].
    Zentralblatt fur Chirurgie, 1985, Volume: 110, Issue:2-3

    Topics: Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Neoplasm Recurrence, Local; Post

1985
Unresectable hepatic metastases from carcinoma of the colon and rectum.
    Surgery, gynecology & obstetrics, 1985, Volume: 160, Issue:5

    Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Carcinoembryon

1985
Sequential methotrexate and 5-fluorouracil in the primary treatment of metastatic colorectal carcinoma.
    American journal of clinical oncology, 1985, Volume: 8, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Fem

1985
Continuous 5-day regional chemotherapy by 5-fluorouracil in colon carcinoma: pharmacokinetic evaluation.
    British journal of cancer, 1985, Volume: 52, Issue:1

    Topics: Aged; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Fluorouracil; Hepatic Artery; Hum

1985
Phase I-II clinical trial of thymidine, 5-FU, and PALA given in combination.
    Cancer treatment reports, 1985, Volume: 69, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic

1985
A phase II study of sequential methotrexate and fluorouracil in advanced colorectal cancer.
    Cancer chemotherapy and pharmacology, 1985, Volume: 15, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Ev

1985
Allopurinol mouthwashes and 5-fluorouracil induced oral toxicity.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1985, Volume: 11, Issue:3

    Topics: Allopurinol; Colonic Neoplasms; Fluorouracil; Humans; Intestinal Mucosa; Mouth Mucosa; Mouthwashes;

1985
Treatment of metastatic colorectal carcinoma with cisplatin and 5-FU.
    Cancer treatment reports, 1985, Volume: 69, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neop

1985
Colorectal cancer: speculations on the role of intraperitoneal therapy.
    Seminars in oncology, 1985, Volume: 12, Issue:3 Suppl 4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Coloni

1985
Adjuvant therapy in rectal cancer: a protocol proposal.
    Seminars in oncology, 1985, Volume: 12, Issue:3 Suppl 4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Inf

1985
Highly sensitive determination of 5-fluorouracil in human plasma by capillary gas chromatography and negative ion chemical ionization mass spectrometry.
    Journal of chromatography, 1985, Sep-13, Volume: 343, Issue:1

    Topics: Alkylation; Bromouracil; Colonic Neoplasms; Fluorouracil; Gas Chromatography-Mass Spectrometry; Huma

1985
Cisplatin plus 5-FU for the treatment of adenocarcinoma of the colon.
    Cancer treatment reports, 1985, Volume: 69, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antige

1985
Cellular basis for the inefficacy of 5-FU in human colon carcinoma.
    Cancer treatment reports, 1985, Volume: 69, Issue:12

    Topics: Cell Count; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Colony-Forming Units Assay;

1985
Phase II study with high-dose N5-10-methyltetrahydrofolate and 5-fluorouracil in advanced colorectal cancer.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug

1985
The chemotherapy of colorectal cancer.
    Cancer, 1974, Volume: 34, Issue:3

    Topics: Administration, Oral; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Infusions,

1974
[Attack on liver cancer--what's the value of diagnosis and treatment?].
    Lakartidningen, 1974, Nov-13, Volume: 71, Issue:46

    Topics: Adult; Aged; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Parenteral; Liver Neoplasms; Middle

1974
Prolonged intra-aortic infusion therapy with anti-tumor agents for advanced cancer of the stomach, colon and rectum.
    The Japanese journal of surgery, 1971, Volume: 1, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Aorta; Bleomycin; Catheterization; Colonic Neoplasms; Cytarabine

1971
The treatment of hepatic metastases by long-term chemotherapeutic infusions.
    Aktuelle Probleme in der Chirurgie, 1970, Volume: 14

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Colonic Neoplasms; Evaluation Studies as Topic; Female;

1970
[Study of the action of antitumor compounds on primary explants from human tumors].
    Antibiotiki, 1967, Volume: 12, Issue:9

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenocarcinoma, Scirrhous; Antibiotics, Antineoplastic; An

1967
[Loco-regional and sequential chemotherapy of advanced cancer].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1968, Volume: 119, Issue:10

    Topics: Adult; Carcinoma; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Dysgerminoma;

1968
Metastatic colorectal carcinoma. Response to hepatic infusion. A review.
    Missouri medicine, 1970, Volume: 67, Issue:3

    Topics: Adult; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Infusions, Parenteral; Liver Neoplasms

1970
Echographic evaluation of abdominal tumor regression during antineoplastic treatment.
    Journal of clinical ultrasound : JCU, 1974, Volume: 2, Issue:2

    Topics: Abdominal Neoplasms; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorub

1974
Chemotherapy of cancer of the colon and rectum.
    Pennsylvania medicine, 1972, Volume: 75, Issue:5

    Topics: Antineoplastic Agents; Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; Nitrosourea Compounds;

1972
Practical aspects of investigation and treatment of colorectal cancer.
    The Medical clinics of North America, 1972, Volume: 56, Issue:3

    Topics: Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Humans; Infusions, Parenteral; Liver Function

1972
Chemotherapy of colon and rectal cancer.
    The Surgical clinics of North America, 1972, Volume: 52, Issue:4

    Topics: Administration, Oral; Antigens, Neoplasm; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasm

1972
Effect of resection of the primary neoplasm on responsiveness to chemotherapy of patients with large bowel cancer.
    Cancer chemotherapy reports, 1972, Volume: 56, Issue:4

    Topics: Adenocarcinoma; Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; Nitrosourea Compounds; Rectal

1972
Chemotherapy of gastrointestinal cancer.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Antineoplastic Agents; Colonic Neoplasms; Esophageal Neoplasms; Floxuridine; Fluorouracil; Gastroint

1972
Intra-arterial combined cancer chemotherapy in technically inoperable carcinoma of the anus and rectum.
    Acta chirurgica Scandinavica, 1974, Volume: 140, Issue:5

    Topics: Aged; Animals; Anus Neoplasms; Daunorubicin; Depression, Chemical; Dogs; Drug Therapy, Combination;

1974
Infusion chemotherapy in hepatoma and metastatic liver tumors.
    American journal of surgery, 1967, Volume: 113, Issue:3

    Topics: Adenocarcinoma; Adolescent; Aged; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury;

1967
[Treatment of cancer of the liver by regional perfusion].
    Journal de chirurgie, 1968, Volume: 95, Issue:2

    Topics: Adult; Aged; Angiography; Carcinoma, Hepatocellular; Catheterization; Colonic Neoplasms; Fluorouraci

1968
[Pathologic anatomy of rectal cancer treated by intra-arterial administration of 5-fluoruracil].
    Arkhiv patologii, 1970, Volume: 32, Issue:8

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Female;

1970
Carcinoma of the colon and rectum in patients up to 25 years of age.
    The American surgeon, 1971, Volume: 37, Issue:4

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adolescent; Adult; Age Factors; Colonic Neoplasms; Female;

1971
Experience with infusion and resection in cancer of the liver.
    Surgery, gynecology & obstetrics, 1974, Volume: 138, Issue:6

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma, Hepatocellular; Catheterization; Colonic Neoplasms; Female

1974
The chemotherapy of large-bowel cancer. Present status and future prospects.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:11

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cricetinae; Culture Techniques; Cyclohexanes; Cyc

1974
Section meeting on reexamination of the old and prospects for new approaches to therapy.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:11

    Topics: Colectomy; Colonic Neoplasms; Cyclohexanes; Cyclophosphamide; Drug Therapy, Combination; Fluorouraci

1974
Intraluminal and intravenous 5-FU chemotherapy adjuvant to surgery for resectable colorectal cancer.
    Panminerva medica, 1974, Volume: 16, Issue:3

    Topics: Administration, Topical; Colonic Neoplasms; Fluorouracil; Humans; Injections, Intravenous; Postopera

1974
Systemic 5-fluorouracil in hepatic metastases from primary colon or rectal cancer.
    New York state journal of medicine, 1972, May-01, Volume: 72, Issue:9

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Injections, Intravenous; Liver Neoplasms; Neoplasm Metastas

1972
Hepatic metastases from rectal and colon cancers. Treatment by infusion of 5-fluorouracil into umbilical vein.
    New York state journal of medicine, 1972, Nov-01, Volume: 72, Issue:21

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Injections, Intravenous; Liver Neoplasms; Neoplasm Metastas

1972
Adjuvant chemotherapy in resectable cancer of the colon and rectum.
    The Surgical clinics of North America, 1972, Volume: 52, Issue:4

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Postoperative Complications; Rectal Neoplasms; Thiotepa

1972
Cancer chemotherapy. I. Methods, agents and overall results in 400 patients.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Amides; Androgens; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Estrogens;

1972
Results of 27 cases with hepatic metastases treated by combination chemotherapy.
    British journal of cancer, 1972, Volume: 26, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Fluorouracil; Humans;

1972
FIVB--a new combination of drugs in the treatment of cancer.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Jun-16, Volume: 47, Issue:23

    Topics: Adenocarcinoma; Aged; Amides; Breast Neoplasms; Colonic Neoplasms; Female; Fluorouracil; Humans; Imi

1973
[Cytostatic therapy of metastazing rectal carcinoma].
    Therapeutische Umschau. Revue therapeutique, 1973, Volume: 30, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Agents; Fluorouracil; Humans; Injections, Intra

1973
Therapy of advanced gastrointestinal cancer with the nitrosoureas.
    Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Bone Marrow Diseases; Carmustine; Colonic Neoplasms; Cyclohex

1973
[Postoperative chemotherapy as means of prophylaxis of recurrences and metastases of cancer of the rectum].
    Klinicheskaia khirurgiia, 1973, Volume: 10

    Topics: Aged; Female; Fluorouracil; Humans; Injections, Intravenous; Neoplasm Metastasis; Neoplastic Cells,

1973
A comprehensive modeling procedure for the human granulopoietic system: over-all view and summary of data.
    Blood, 1973, Volume: 42, Issue:2

    Topics: Aged; Animals; Blood Platelets; Bone Marrow Cells; Erythropoiesis; Feedback; Female; Fluorouracil; H

1973
Scan evidence of decrease in size of intrahepatic tumors after chemotherapy. A case report.
    Gastroenterology, 1974, Volume: 67, Issue:3

    Topics: Adult; Aged; Carcinoma, Transitional Cell; Cecal Neoplasms; Doxorubicin; Female; Fluorouracil; Human

1974
[Effects of 5-FU (5-fluorouracil) in 4.3MeV Linac x-ray treatment of advanced cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1968, Volume: 14, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Fl

1968
[Clinico-morphologic analysis of the results of long-term intra-arterial chemotherapy of the far advanced stages of rectal cancer].
    Voprosy onkologii, 1968, Volume: 14, Issue:11

    Topics: Adenocarcinoma; Adult; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluoroura

1968
5-Hydroxyindole-secreting rectal carcinoid tumour.
    Gut, 1972, Volume: 13, Issue:5

    Topics: Adult; Carcinoid Tumor; Duodenal Ulcer; Female; Fluorouracil; Humans; Hydroxyindoleacetic Acid; Live

1972
Chemotherapy of colorectal cancer.
    American journal of proctology, 1972, Volume: 23, Issue:4

    Topics: Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Neoplasm Recurrence, Local; Rectal Neoplasms

1972
Results of treatment of malignant tumors with ftorafur.
    Cancer, 1972, Volume: 30, Issue:2

    Topics: Antimetabolites; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Colonic Neoplasms; Deoxyr

1972
[Combined application of drugs in cancer chemotherapy with special reference to the combination of mitomycin C, 5-fluorouracil, and cytosine arabinoside].
    Gan no rinsho. Japan journal of cancer clinics, 1972, Volume: 18, Issue:2

    Topics: Cytarabine; Female; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Mitomycins; Neoplasm

1972
[Local intra-arterial infusion chemotherapy of malignant tumor--successful treatment by intra-arterial infusion of 5-fluorouracil and mitomycin C in cases of unresectable cancer of the liver, stomach, colon and rectum].
    Naika. Internal medicine, 1971, Volume: 27, Issue:6

    Topics: Adult; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Infant; Injections, Intra-Arterial; Li

1971
Circulating cancer cells: pre- and post-chemotherapy observations.
    Cancer, 1971, Volume: 28, Issue:3

    Topics: Adenocarcinoma; Breast Neoplasms; Colonic Neoplasms; Female; Filtration; Fluorouracil; Humans; Male;

1971
Treatment of metastatic colorectal carcinoma with 5-fluorouracil by mouth.
    Cancer, 1971, Volume: 28, Issue:4

    Topics: Administration, Oral; Aged; Bone Neoplasms; Colonic Neoplasms; Female; Fluorouracil; Humans; Liver C

1971
Chemotherapy for metastatic colorectal liver carcinoma by intra-aortic infusion.
    Cancer, 1971, Volume: 28, Issue:5

    Topics: Antineoplastic Agents; Aorta, Abdominal; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms

1971
[Electrolyte secreting rectal tumor].
    Nordisk medicin, 1971, Sep-02, Volume: 86, Issue:35

    Topics: Adenoma; Aged; Fluorouracil; Humans; Male; Rectal Neoplasms; Water-Electrolyte Balance

1971
Combination cancer chemotherapy by regional intra-arterial or intra-aortic infusion of 5-fluorouracil and mitomycin-C with or without irradiation.
    The Japanese journal of surgery, 1971, Volume: 1, Issue:2

    Topics: Aorta; Cobalt Radioisotopes; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Hea

1971
Cytotoxic penetration and concentration in human malignant tumours.
    The British journal of surgery, 1969, Volume: 56, Issue:10

    Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Female; Fluorouracil; Humans; Injections

1969
The use of chemotherapy in advanced carcinoma of the rectum.
    Proceedings of the Royal Society of Medicine, 1969, Dec-12, Volume: 62, Issue:12

    Topics: Cyclophosphamide; Fluorouracil; Humans; Injections, Intra-Arterial; Leukopenia; Male; Mechlorethamin

1969
Comparative study of monthly courses versus weekly doses of 5-fluorouracil (NSC-19893).
    Cancer chemotherapy reports, 1969, Volume: 53, Issue:4

    Topics: Adult; Breast Neoplasms; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplas

1969
Survival of patients treated with systemic fluorouracil for hepatic metastases.
    Surgery, gynecology & obstetrics, 1970, Volume: 130, Issue:5

    Topics: Adult; Age Factors; Aged; Carcinoma; Colonic Neoplasms; Female; Fluorouracil; Follow-Up Studies; Hum

1970
Treatment of hepatic tumours.
    Digestion, 1970, Volume: 3, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Agents; Female; Fluorouracil; Hepatic Artery; Humans; Laparotomy; Lei

1970
[Treatment of metastases to the liver in the course of sigmoid and rectal cancer].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1970, Nov-16, Volume: 25, Issue:46

    Topics: Female; Fluorouracil; Follow-Up Studies; Humans; Liver Neoplasms; Male; Methods; Neoplasm Metastasis

1970
One-shot infusion of non-surgically administered mitomycin C in the celiac artery for liver metastases. Clinical effects.
    International surgery, 1970, Volume: 54, Issue:6

    Topics: Adult; Aged; Angiography; Blood Cell Count; Blood Platelets; Celiac Artery; Colonic Neoplasms; Femal

1970
[5-fluorouracil concentration in the blood of patients with rectal cancer following regional drug administration].
    Voprosy onkologii, 1970, Volume: 16, Issue:6

    Topics: Fluorouracil; Humans; Injections, Intra-Arterial; Injections, Intravenous; Rectal Neoplasms

1970
[Intra-portal infusion of 5-fluorouracil for metastasis of rectal cancer into the liver].
    Klinicheskaia khirurgiia, 1970, Volume: 12

    Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Humans; Liver Neoplasms; Middle

1970
[The possibilities of drug therapy in metastazing carcinoma of the large intestine].
    Schweizerische medizinische Wochenschrift, 1967, May-06, Volume: 97, Issue:18

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Neoplasm Metastasis; Rectal Neoplasms

1967
Clinical evaluation of combined radiation and chemotherapy in gastrointestinal malignancies.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1968, Volume: 102, Issue:3

    Topics: Bone Marrow; Bone Marrow Cells; Colonic Neoplasms; Fluorouracil; Gastrointestinal Neoplasms; Humans;

1968
Carcinoma of the colon and rectum.
    American journal of surgery, 1968, Volume: 116, Issue:1

    Topics: Adenocarcinoma; Aged; Colonic Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic

1968
The role of chemotherapy in the treatment of colorectal cancer.
    Virginia medical monthly, 1968, Volume: 95, Issue:5

    Topics: Colonic Neoplasms; Fluorouracil; Humans; Rectal Neoplasms

1968
Oral administration of fluorouracil. A preliminary trial.
    Archives of surgery (Chicago, Ill. : 1960), 1968, Volume: 97, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Alopecia; Bile Duct Neoplasms; Colonic Neoplasms; Diarrhea; Fluorouraci

1968
[Clinical application of 5-fluorouracil--with special reference to the evaluation of the intravenous administration method].
    Gan no rinsho. Japan journal of cancer clinics, 1968, Volume: 14, Issue:9

    Topics: Adult; Antineoplastic Agents; Female; Fluorouracil; Humans; Injections, Intravenous; Male; Methods;

1968
Prolonged continuous hepatic infusion. Results with fluorouracil for primary and metastatic cancer in the liver.
    Archives of surgery (Chicago, Ill. : 1960), 1969, Volume: 99, Issue:2

    Topics: Adult; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Female; Fluorou

1969
Local injection of fluorouracil in skin cancer.
    JAMA, 1969, Apr-21, Volume: 208, Issue:3

    Topics: Adenocarcinoma; Fluorouracil; Humans; Injections; Male; Middle Aged; Neoplasm Recurrence, Local; Per

1969
Intraluminal chemotherapy adjuvant (HN2 or 5-FU) to operation for cancer of the colon and rectum. Follow-up report of 83 cases.
    Annals of surgery, 1965, Volume: 162, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Humans; Mechlorethamine; Middle

1965
Chemotherapy for liver cancer by protracted ambulatory infusion.
    JAMA, 1965, Nov-01, Volume: 194, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Hepatic Artery; Humans

1965