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fluorouracil and Cancer of Pituitary

fluorouracil has been researched along with Cancer of Pituitary in 8 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"5T) was performed in 191 female CMF (Cyclophosphamide, Methotrexate, 5-Fluorouracil) chemotherapy-exposed breast cancer survivors."3.77Incidental findings on brain Magnetic Resonance Imaging in long-term survivors of breast cancer treated with adjuvant chemotherapy. ( Boogerd, W; Breteler, MM; Koppelmans, V; Poels, MM; Schagen, SB; Seynaeve, C; van der Lugt, A, 2011)
"However, the presence of metastases separate from the pituitary in the central nervous system or at a distance is necessary to designate pituitary tumors as carcinomas, i."1.30The role of cytotoxic chemotherapy in the management of aggressive and malignant pituitary tumors. ( Besser, GM; Grossman, AB; Kaltsas, GA; Monson, JP; Mukherjee, JJ; Plowman, PN, 1998)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
AbdelBaki, MS1
Waguespack, SG1
Salceda, V1
Jones, J1
Stapleton, SL1
Baskin, DS1
Okcu, MF1
Lundgren, JA1
Oldfield, EH1
Marshall, JC1
Koppelmans, V1
Schagen, SB1
Poels, MM1
Boogerd, W1
Seynaeve, C1
van der Lugt, A1
Breteler, MM1
Lin, CS1
Lin, SH1
Chiang, YH1
Sheu, LF1
Chao, TY1
Ferguson, T1
Kaltsas, GA1
Mukherjee, JJ1
Plowman, PN1
Monson, JP1
Grossman, AB1
Besser, GM1
Lamberts, SW1
van Koetsveld, P1
Hofland, LJ1
Wilson, CB1
Winternitz, WW1
Rush, BF1
Walton, KN1
Maddy, JA1

Reviews

1 review available for fluorouracil and Cancer of Pituitary

ArticleYear
Significant response of pituitary carcinoma to carboplatin, leucovorin and fluorouracil chemotherapy: a pediatric case report and review of the literature.
    Journal of neuro-oncology, 2017, Volume: 135, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carc

2017

Other Studies

7 other studies available for fluorouracil and Cancer of Pituitary

ArticleYear
The longest stalk: preserved pituitary function after regression of a giant prolactinoma.
    Pituitary, 2017, Volume: 20, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Fluorouracil; Humans; M

2017
Incidental findings on brain Magnetic Resonance Imaging in long-term survivors of breast cancer treated with adjuvant chemotherapy.
    European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:17

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brea

2011
Diabetes insipidus revealing an isolated pituitary stalk metastasis of breast cancer.
    European journal of neurology, 2007, Volume: 14, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast;

2007
Prevention and delay of spontaneous mammary and pituitary tumors by long- and short-term ingestion of 5-fluorouracil in Wistar-Furth rats.
    Oncology, 1980, Volume: 37, Issue:5

    Topics: Age Factors; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluoro

1980
The role of cytotoxic chemotherapy in the management of aggressive and malignant pituitary tumors.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:12

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined C

1998
The interrelationship between the anti-mitotic action of the somatostatin analog octreotide and that of cytostatic drugs and suramin.
    International journal of cancer, 1991, Jul-30, Volume: 48, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Int

1991
Cryohypophysectomy: indications, technic, and results.
    International surgery, 1967, Volume: 48, Issue:1

    Topics: Acromegaly; Adenoma, Chromophobe; Adult; Breast Neoplasms; Carcinoma; Castration; Cryosurgery; Cushi

1967