fluorouracil has been researched along with Cancer of Nose in 31 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Differentiating a KA from a squamous cell carcinoma (SCC) is important for treatment implications but is often challenging." | 6.61 | Treatment of Solitary Keratoacanthoma of the Nose With Intralesional Methotrexate and Review of the Literature ( Doerfler, L; Hanke, CW, 2019) |
| "To analyze clinical and pharmacokinetic data of cisplatin (CP)/fluorouracil (FU)/l folinic acid (l FA) chemotherapy administered as first-line treatment to locally advanced head and neck cancer patients." | 2.68 | Phase II trial of cisplatin, fluorouracil, and pure folinic acid for locally advanced head and neck cancer: a pharmacokinetic and clinical survey. ( Dassonville, O; Demard, F; Etienne, MC; Guillot, T; Milano, G; Mobayen, H; Otto, J; Saudes, L; Schneider, M; Thyss, A, 1995) |
| "Differentiating a KA from a squamous cell carcinoma (SCC) is important for treatment implications but is often challenging." | 2.61 | Treatment of Solitary Keratoacanthoma of the Nose With Intralesional Methotrexate and Review of the Literature ( Doerfler, L; Hanke, CW, 2019) |
| "We reviewed 21 patients diagnosed with HNSCC of the PNSNC who were treated with IC." | 1.43 | Induction chemotherapy in head and neck squamous cell carcinoma of the paranasal sinus and nasal cavity: a role in organ preservation. ( Hah, JH; Han, DH; Heo, DS; Keam, B; Kim, DW; Kim, DY; Kim, TM; Kwon, TK; Lee, SH; Ock, CY; Rhee, CS; Sung, MW; Won, TB; Wu, HG, 2016) |
| "Renal cell carcinoma is an uncommon tumor in adults." | 1.33 | Solitary metastasis in a nasal fossa as the first manifestation of a renal carcinoma. ( Alcaide-García, J; Alés-Díaz, I; Benavides-Orgaz, M; Cobo-Dols, M; Gil-Calle, S; Gutiérrez-Calderón, V; Montesa-Pino, A; Villar-Chamorro, E, 2006) |
| "To improve the results, we have treated the squamous cell carcinomas with topical 5-fluorouracil to obtain sensitization and shrinkage of the tumor before resection." | 1.27 | Topical 5-fluorouracil in treatment of carcinoma of nasal floor and nasal alae. ( Marks, MW; Ryan, RF, 1988) |
| "Thyroid cancer, nasal cancer and paranasal sinus cancer gave the best results." | 1.27 | [Chemotherapy with FT-207 suppository (Futraful Supo) in head and neck cancer--cooperative studies by six medical schools in Kanagawa Prefecture]. ( Hattori, Y; Horiuchi, M; Miyake, H; Murakami, T; Otake, H; Sawaki, S; Takahashi, H; Takeyama, I; Tamamushi, N; Yao, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (45.16) | 18.7374 |
| 1990's | 4 (12.90) | 18.2507 |
| 2000's | 5 (16.13) | 29.6817 |
| 2010's | 7 (22.58) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Chai, Y | 1 |
| Wei, Y | 1 |
| Zhang, D | 1 |
| Qi, F | 1 |
| Dong, M | 1 |
| Doerfler, L | 1 |
| Hanke, CW | 2 |
| Poulalhon, N | 1 |
| Dalle, S | 1 |
| Balme, B | 1 |
| Thomas, L | 1 |
| Homma, A | 1 |
| Nakamaru, Y | 1 |
| Sakashita, T | 1 |
| Onimaru, R | 1 |
| Terasaka, S | 1 |
| Tsuchiya, K | 1 |
| Yoshida, D | 1 |
| Yasuda, K | 1 |
| Hatakeyama, H | 1 |
| Furusawa, J | 1 |
| Mizumachi, T | 1 |
| Kano, S | 1 |
| Shirato, H | 1 |
| Fukuda, S | 1 |
| Ock, CY | 1 |
| Keam, B | 1 |
| Kim, TM | 1 |
| Han, DH | 1 |
| Won, TB | 1 |
| Lee, SH | 1 |
| Hah, JH | 1 |
| Kwon, TK | 1 |
| Kim, DW | 1 |
| Kim, DY | 1 |
| Rhee, CS | 1 |
| Wu, HG | 1 |
| Sung, MW | 1 |
| Heo, DS | 1 |
| Yasumatsu, R | 1 |
| Nakashima, T | 1 |
| Sato, M | 1 |
| Nakano, T | 1 |
| Kogo, R | 1 |
| Hashimoto, K | 1 |
| Sawatsubashi, M | 1 |
| Nakagawa, T | 1 |
| Chen, NX | 1 |
| Zhang, XX | 1 |
| Chen, L | 1 |
| Wang, JL | 1 |
| Yan, F | 1 |
| Ma, L | 1 |
| Khasanov, AI | 1 |
| Nagano, H | 1 |
| Yoshifuku, K | 1 |
| Deguchi, K | 1 |
| Kurono, Y | 1 |
| Khademi, B | 1 |
| Moradi, A | 1 |
| Hoseini, S | 1 |
| Mohammadianpanah, M | 1 |
| JOHNSON, RO | 1 |
| LANGE, RD | 1 |
| KISKEN, WA | 1 |
| CURRERI, AR | 1 |
| BAKER, RR | 1 |
| GAERTNER, RA | 1 |
| Nitsche, M | 1 |
| Hermann, RM | 1 |
| Christiansen, H | 1 |
| Berger, J | 1 |
| Pradier, O | 1 |
| Cobo-Dols, M | 1 |
| Alés-Díaz, I | 1 |
| Villar-Chamorro, E | 1 |
| Gil-Calle, S | 1 |
| Alcaide-García, J | 1 |
| Montesa-Pino, A | 1 |
| Gutiérrez-Calderón, V | 1 |
| Benavides-Orgaz, M | 1 |
| Leonard, AL | 1 |
| Hibino, S | 1 |
| Narayanan, K | 1 |
| Liang, MD | 1 |
| Jacobs, SA | 1 |
| Schneider, M | 1 |
| Etienne, MC | 1 |
| Milano, G | 1 |
| Thyss, A | 1 |
| Otto, J | 1 |
| Dassonville, O | 1 |
| Mobayen, H | 1 |
| Saudes, L | 1 |
| Guillot, T | 1 |
| Demard, F | 1 |
| Chan, RC | 1 |
| Shukovsky, LJ | 1 |
| Cappellano, RS | 1 |
| Cintra, RA | 1 |
| Björk-Eriksson, T | 1 |
| Mercke, C | 1 |
| Petruson, B | 1 |
| Ekholm, S | 1 |
| Polonowski, JM | 1 |
| Brasnu, D | 1 |
| Roux, FX | 1 |
| Bassot, V | 1 |
| Ryan, RF | 1 |
| Marks, MW | 1 |
| Sawaki, S | 1 |
| Tamamushi, N | 1 |
| Takahashi, H | 1 |
| Yao, K | 1 |
| Takeyama, I | 1 |
| Otake, H | 1 |
| Miyake, H | 1 |
| Horiuchi, M | 1 |
| Hattori, Y | 1 |
| Murakami, T | 1 |
| Cruz, AB | 1 |
| McInnis, WD | 1 |
| Aust, JB | 1 |
| Sparwald, E | 1 |
| Müllensiefen, C | 1 |
| Lange, G | 1 |
| Slanina, I | 1 |
| The, KK | 1 |
| Goepfert, H | 1 |
| Jesse, RH | 1 |
| Lindberg, RD | 1 |
| Littlewood, M | 1 |
| Murray, DS | 1 |
| Litwin, MS | 1 |
| Krementz, ET | 1 |
| Braun-Falco, O | 1 |
| Lukacs, I | 1 |
| Inuyama, Y | 1 |
| Matsukawa, J | 1 |
| Sato, Y | 1 |
| Morita, M | 1 |
| Watanabe, T | 1 |
2 reviews available for fluorouracil and Cancer of Nose
| Article | Year |
|---|---|
Treatment of Solitary Keratoacanthoma of the Nose With Intralesional Methotrexate and Review of the Literature
Topics: Antineoplastic Agents; Biopsy; Bleomycin; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; In | 2019 |
Malignant neoplasms of the sinonasal tract: report of 71 patients and literature review and analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma; Child; Child, Preschoo | 2009 |
3 trials available for fluorouracil and Cancer of Nose
| Article | Year |
|---|---|
Phase II trial of cisplatin, fluorouracil, and pure folinic acid for locally advanced head and neck cancer: a pharmacokinetic and clinical survey.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fe | 1995 |
Potential impact on tumor control and organ preservation with cisplatin and 5-fluorouracil for patients with advanced tumors of the paranasal sinuses and nasal fossa. A prospective pilot study.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 1992 |
A clinical trial of the use of 5-fluouracil in the treatment of some cutaneous malignancies.
Topics: Adult; Aged; Carcinoma, Basal Cell; Clinical Trials as Topic; Facial Neoplasms; Female; Fluorouracil | 1973 |
26 other studies available for fluorouracil and Cancer of Nose
| Article | Year |
|---|---|
Comparing the role of different treatment modalities in locoregionally advanced olfactory neuroblastoma: The 20-year clinical experience of a single institution.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Esthesioneuroblastoma, Olfactory; | 2023 |
Fast-growing cutaneous squamous cell carcinoma in a patient treated with vismodegib.
Topics: Aged, 80 and over; Anilides; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Basa | 2015 |
Management for squamous cell carcinoma of the nasal cavity and ethmoid sinus: A single institution experience.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino | 2015 |
Induction chemotherapy in head and neck squamous cell carcinoma of the paranasal sinus and nasal cavity: a role in organ preservation.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, | 2016 |
Clinical management of squamous cell carcinoma associated with sinonasal inverted papilloma.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemor | 2017 |
[Clinical analysis of multimodal treatment for orbital organ preservation in T4b squamous cell carcinoma of nasal cavity and paranasal sinuses].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cis | 2016 |
[Influence of chemotherapy regimen on antioxidant level in patients with locally-advanced tumors of the maxilla, nasal and paranasal sinuses].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Chemotherapy, | 2009 |
Adenocarcinoma of the paranasal sinuses and nasal cavity with lung metastasis showing complete response to combination chemotherapy with docetaxel, cisplatin and 5-fluorouracil (TPF): a case report.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease-Free Survival; Do | 2010 |
INFUSION OF 5-FLUOROURACIL IN CYLINDROMA TREATMENT.
Topics: Carcinoma; Carcinoma, Adenoid Cystic; Carcinoma, Basal Cell; Fluorouracil; Humans; Injections, Intra | 1964 |
REGIONAL ARTERIAL INFUSION OF ANTIMETABOLITES. AN ANALYSIS OF THE RESULTS OBTAINED IN 33 PATIENTS WITH MALIGNANT TUMORS OF THE HEAD AND NECK.
Topics: Antimetabolites; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; H | 1965 |
Rationale for individualized therapy in Sinonasal Teratocarcinosarcoma (SNTC): case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinosarcoma; Cisplatin; Combined Modality | 2005 |
Solitary metastasis in a nasal fossa as the first manifestation of a renal carcinoma.
Topics: Adenocarcinoma, Clear Cell; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carc | 2006 |
Treatment of giant keratoacanthoma with intralesional 5-fluorouracil.
Topics: Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Gestati | 2006 |
Combined chemotherapy and radiation in the treatment of a large nasal cavity tumor: a case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined | 1995 |
Effects of irradiation on the eye.
Topics: Blindness; Cataract; Eye; Eye Diseases; Fluorouracil; Humans; Nose Neoplasms; Paranasal Sinus Neopla | 1976 |
[Continuous intra-arterial antiblastic chemotherapy in the treatment of rhinopharyngeal tumors invading the skull base. Association with radiotherapy].
Topics: Carcinoma, Squamous Cell; Fluorouracil; Humans; Injections, Intra-Arterial; Middle Aged; Neoplasm Me | 1975 |
Esthesioneuroblastoma. Complete tumor response after induction chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Female; Fluorouracil; Humans; Inf | 1990 |
Topical 5-fluorouracil in treatment of carcinoma of nasal floor and nasal alae.
Topics: Administration, Topical; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Combined Modality Th | 1988 |
[Chemotherapy with FT-207 suppository (Futraful Supo) in head and neck cancer--cooperative studies by six medical schools in Kanagawa Prefecture].
Topics: Adult; Aged; Anorexia; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; | 1985 |
Triple drug intra-arterial infusion combined with x-ray therapy and surgery for head and neck cancer.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Head and N | 1974 |
[Clinical results after synchronised radiotherapy in 21 cases of human malignomas (author's transl)].
Topics: Adult; Aged; Facial Neoplasms; Female; Fluorouracil; Follow-Up Studies; Germany, West; Humans; Laryn | 1974 |
Arterial infusion and radiation therapy in the treatment of advanced cancer of the nasal cavity and paranasal sinuses.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Carotid Artery, External; Carotid Artery, Internal; Chemot | 1973 |
Treatment of basal and squamous cancers of the nose and ear with 5-fluorouracil cream.
Topics: Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Fluorouracil; Follow-U | 1971 |
[Hypernephroma metastases of the skin and therapeutic possiblities].
Topics: Adenocarcinoma; Aged; Fluorouracil; Humans; Kidney Neoplasms; Male; Neoplasm Metastasis; Nose Neopla | 1971 |
[Effect of 5-fluorouracil and bleomycin on malignant head and neck tumors].
Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Female; Fluorouracil; Humans; Injec | 1969 |
[Cancer chemotherapeutic agents].
Topics: Antineoplastic Agents; Fluorouracil; Humans; Nose Neoplasms; Sarcoma | 1969 |