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fluorouracil and Cancer of Maxillary Sinus

fluorouracil has been researched along with Cancer of Maxillary Sinus in 25 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Sinonasal undifferentiated carcinoma (SNUC) is a rare and aggressive malignancy with optimal management remains unclear."3.87Trimodality management of sinonasal undifferentiated carcinoma and review of the literature. ( Culliney, B; Harrison, LB; Hauerstock, D; Hu, KS; Jacobson, A; Li, Z; Manolidis, S; Mourad, WF; Persky, M; Schantz, S; Shourbaji, RA; Tran, T; Urken, M, 2013)
"Sinonasal undifferentiated carcinoma (SNUC) represents less than 1% of all malignancies."2.53Management of sinonasal undifferentiated carcinoma with intracerebral invasion: Clinical experience at a single institution and review of the literature. ( Clauditz, T; Knecht, R; Laban, S; Muenscher, A; Schafhausen, P; Tribius, S; Veldhoen, S; Zielinski, V, 2016)
" Patients in the P+M group who received a 5-fluorouracil (5-FU) dosage of more than 3500 mg had a better 5-year local control rate than patients who received a 5-FU dosage of less than 3500 mg (p = 0."1.31Trimodal combination therapy for maxillary sinus carcinoma. ( Amagasa, T; Enomoto, S; Kishimoto, S; Miura, M; Ogura, I; Shibuya, H; Yoshimura, R, 2002)
"From 1972 to 1986, 108 patients with squamous cell carcinoma of the maxillary sinus were treated at the Department of Radiology, University of Tokyo Hospital."1.29Analysis of the results of combined therapy for maxillary carcinoma. ( Akanuma, A; Aoki, Y; Hasezawa, K; Karasawa, K; Muta, N; Nakagawa, K; Onogi, Y; Sakata, K; Sasaki, Y; Terahara, A, 1993)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19906 (24.00)18.7374
1990's5 (20.00)18.2507
2000's8 (32.00)29.6817
2010's6 (24.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zielinski, V1
Laban, S1
Tribius, S1
Schafhausen, P1
Veldhoen, S1
Knecht, R1
Clauditz, T1
Muenscher, A1
Yasumatsu, R2
Nakashima, T2
Sato, M1
Nakano, T1
Kogo, R1
Hashimoto, K1
Sawatsubashi, M1
Nakagawa, T1
Kovács, AF1
Eberlein, K1
Hülsmann, T1
Yamauchi, M1
Wakasaki, T1
Masuda, M1
Komune, S1
Nishino, H2
Takanosawa, M1
Kawada, K1
Kanazawa, T2
Ichimura, K3
Takahashi, S1
Nakazawa, M1
Mourad, WF1
Hauerstock, D1
Shourbaji, RA1
Hu, KS1
Culliney, B1
Li, Z1
Jacobson, A1
Tran, T1
Manolidis, S1
Schantz, S1
Urken, M1
Persky, M1
Harrison, LB1
Choi, IJ1
Kim, DW1
Kim, DY1
Lee, CH1
Rhee, CS1
Yao, K1
Takahashi, H1
Inagi, K1
Nakayama, M1
Makoshi, T1
Nagai, H1
Okamoto, M1
Isobe, K1
Uno, T1
Hanazawa, T1
Kawakami, H1
Yamamoto, S1
Suzuki, H2
Iida, Y1
Ueno, N1
Okamoto, Y1
Ito, H1
Su, YR1
Wu, GH1
Zeng, ZY1
Guo, ZM1
Chen, WK1
Wei, MW1
Chen, YF1
Sakata, K1
Aoki, Y1
Karasawa, K1
Nakagawa, K1
Hasezawa, K1
Muta, N1
Terahara, A2
Onogi, Y1
Sasaki, Y1
Akanuma, A1
Kim, GE1
Chang, SK1
Lee, SW1
Pyo, HR1
Choi, EC1
Roh, JK1
Keum, KC1
Lee, CG1
Suh, CO1
Miyata, M1
Morita, M1
Ishikawa, K1
Nibu, K1
Sugasawa, M1
Asai, M1
Mochiki, M1
Kawahara, N1
Asato, H1
Yoshimura, R1
Shibuya, H1
Ogura, I1
Miura, M1
Amagasa, T1
Enomoto, S1
Kishimoto, S1
Sakai, S3
Mori, N2
Miyaguchi, M2
Itoh, M2
Inokuchi, T1
Sano, K1
Kaminogo, M1
Lee, YY1
Dimery, IW1
Van Tassel, P1
De Pena, C1
Blacklock, JB1
Goepfert, H1
Inuyama, Y1
Kawaura, M1
Toji, M1
Tanaka, K1
Ookuma, A1
Kawasaki, K1
Imano, Y1
Hayashizaki, K1
Kaneko, T1
Tsujii, H1
Kamada, T1
Arimoto, T1
Mizoe, J1
Shirato, H1
Matsuoka, Y1
Irie, G1
Matsuura, S2
Makino, S2
Satake, B2
Shimizu, R1
Maehara, Y1
Sakaino, K1
Nozaki, M1
Matsumoto, M1

Reviews

3 reviews available for fluorouracil and Cancer of Maxillary Sinus

ArticleYear
Management of sinonasal undifferentiated carcinoma with intracerebral invasion: Clinical experience at a single institution and review of the literature.
    Ear, nose, & throat journal, 2016, Volume: 95, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Chemoradiotherapy

2016
Trimodality management of sinonasal undifferentiated carcinoma and review of the literature.
    American journal of clinical oncology, 2013, Volume: 36, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradi

2013
Neoadjuvant chemotherapy and radiation for inoperable carcinoma of the maxillary antrum: a matched-control study.
    American journal of clinical oncology, 2000, Volume: 23, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous

2000

Trials

2 trials available for fluorouracil and Cancer of Maxillary Sinus

ArticleYear
Organ preservation treatment using TPF-a pilot study in patients with advanced primary and recurrent cancer of the oral cavity and the maxillary sinus.
    Oral and maxillofacial surgery, 2009, Volume: 13, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P

2009
Trimodality management of sinonasal undifferentiated carcinoma and review of the literature.
    American journal of clinical oncology, 2013, Volume: 36, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradi

2013

Other Studies

21 other studies available for fluorouracil and Cancer of Maxillary Sinus

ArticleYear
Clinical management of squamous cell carcinoma associated with sinonasal inverted papilloma.
    Auris, nasus, larynx, 2017, Volume: 44, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemor

2017
Thymidylate synthase expression as a predictor of clinical response to 5-fluorouracil-based chemoradiotherapy in patients with maxillary sinus squamous cell carcinoma.
    Auris, nasus, larynx, 2011, Volume: 38, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; B

2011
Multidisciplinary therapy consisting of minimally invasive resection, irradiation, and intra-arterial infusion of 5-fluorouracil for maxillary sinus carcinomas.
    Head & neck, 2013, Volume: 35, Issue:6

    Topics: Antimetabolites, Antineoplastic; Carcinoma; Female; Fluorouracil; Follow-Up Studies; Humans; Infusio

2013
Predictive markers for neoadjuvant chemotherapy in advanced squamous cell carcinoma of maxillary sinus: Preliminary report.
    Acta oto-laryngologica, 2013, Volume: 133, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinom

2013
Treatment of maxillary sinus carcinoma: clinical results using the Kitasato modality.
    Acta oto-laryngologica. Supplementum, 2002, Issue:547

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Protocols; Carcinoma; Combined

2002
Preoperative chemotherapy and radiation therapy for squamous cell carcinoma of the maxillary sinus.
    Japanese journal of clinical oncology, 2005, Volume: 35, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous

2005
[Treatment of advanced maxillary sinus squamous carcinoma: an analysis of 92 cases].
    Ai zheng = Aizheng = Chinese journal of cancer, 2008, Volume: 27, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Ci

2008
Analysis of the results of combined therapy for maxillary carcinoma.
    Cancer, 1993, May-01, Volume: 71, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Carcinoma, Squamous Cell; Combine

1993
Combined therapy with conservative surgery, radiotherapy, and regional chemotherapy for maxillary sinus carcinoma.
    Cancer, 2000, Nov-01, Volume: 89, Issue:9

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Maxi

2000
Results of multimodality therapy for squamous cell carcinoma of maxillary sinus.
    Cancer, 2002, Mar-01, Volume: 94, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co

2002
Trimodal combination therapy for maxillary sinus carcinoma.
    International journal of radiation oncology, biology, physics, 2002, Jul-01, Volume: 53, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combin

2002
Combined therapy for maxillary sinus carcinoma with special reference to extensive Denker's operation.
    Auris, nasus, larynx, 1991, Volume: 18, Issue:4

    Topics: Adult; Aged; Combined Modality Therapy; Fluorouracil; Humans; Maxillary Sinus Neoplasms; Middle Aged

1991
[The role of extensive Denkers operation in combined therapy for maxillary sinus carcinoma].
    Nihon Jibiinkoka Gakkai kaiho, 1991, Volume: 94, Issue:2

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Humans; Infusi

1991
Osteoradionecrosis of sphenoid and temporal bones in a patient with maxillary sinus carcinoma: a case report.
    Oral surgery, oral medicine, and oral pathology, 1990, Volume: 70, Issue:3

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Humans; Male; Maxillary Sinus Neo

1990
Treatment and results of maxillary sinus carcinoma.
    Otolaryngologia polska = The Polish otolaryngology, 1990, Volume: 44, Issue:3

    Topics: Cryosurgery; Curettage; Fluorouracil; Humans; Japan; Maxillary Sinus; Maxillary Sinus Neoplasms; Med

1990
Superselective intra-arterial chemotherapy of advanced paranasal sinus tumors.
    Archives of otolaryngology--head & neck surgery, 1989, Volume: 115, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Ch

1989
[Intra-arterial chemotherapy of maxillary sinus carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma

1989
[Treatment of head and neck neoplasms].
    Gan no rinsho. Japan journal of cancer clinics, 1989, Volume: Spec No

    Topics: Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal Neopl

1989
The role of radiotherapy in the management of maxillary sinus carcinoma.
    Cancer, 1986, Jun-15, Volume: 57, Issue:12

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Evaluation Studies as Topic; Femal

1986
[An evaluation of the multidisciplinary treatment of carcinoma of the maxillary antrum in head and neck surgery].
    Gan no rinsho. Japan journal of cancer clinics, 1986, Volume: 32, Issue:13

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Humans; Maxillary Sinus; Maxillar

1986
[Radiotherapy in trimodal combination therapy of maxillary sinus squamous cell carcinoma].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:8

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intra-

1985