fluorouracil has been researched along with Cancer of Lip in 20 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Laser therapy appears the best option among nonsurgical approaches for actinic cheilitis, and PDT showed higher efficacy when sequentially combined with 5% imiquimod." | 5.05 | Treatments of actinic cheilitis: A systematic review of the literature. ( Cornacchia, L; Lai, M; Longo, C; Pampena, R; Pellacani, G; Peris, K, 2020) |
| "The authors describe the first case of myocardial infarction in their department which occurred during 5-fluorouracil treatment." | 3.67 | [The development of myocardial infarct in a patient treated with 5-fluorouracil]. ( Bulas, J; Cerná, M; Danko, J; Kasper, J; Murín, J; Uhliar, R, 1989) |
| "15 patients with superficial basaliomas or premalignant epithelial neoplastic disorders (actinic keratosis, leukoplakia, Bowen's disease) were treated locally over three weeks with retinoic acid (RA) alone or in combination with 5-fluorouracil (5-FU)." | 3.66 | [Vitamin A acid for the topical management of epithelial neoplasms. Combination with 5-fluorouracil]. ( Kurka, M; Orfanos, CE; Pullmann, H, 1978) |
| "122 patients with primary squamous cell carcinoma of the lip, the oral cavity and the oropharynx have been treated with 100 mg/m2 cisplatin bolus infusion and 120-h continuous infusion of 1000 mg/m2 5-fluorouracil following radical surgery; 99 patients completed all 3 cycles." | 2.71 | Postoperative chemotherapy with cisplatin and 5-fluorouracil in cancer of the oral cavity and the oropharynx--long-term results. ( Bitter, K; Ghahremani, MT; Kovács, AF; Stefenelli, U, 2003) |
| "Many cases with metastatic hepatic cancer have a poor prognosis because of the appearance of extrahepatic lesions in spite of the fact that a partial response can be obtained by hepatic arterial infusion chemotherapy." | 1.30 | [Appearance of extrahepatic lesions in the superior lip and orbit of a patient with liver metastases of gastric cancer following partial response by hepatic arterial infusion chemotherapy]. ( Hasegawa, K; Ichikawa, T; Kawai, S; Kirihara, M; Kume, S; Maruo, H; Tominaga, S, 1998) |
| "Histologic characteristics of squamous cell carcinoma include loss of cell organization and orientation, loss of intercellular bridges, presence of nuclear atypia and mitotic figures, and premature cell keratinization." | 1.27 | Skin lesions from sun exposure: a treatment guide. ( Gibson, LE; Perry, HO, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (50.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lai, M | 1 |
| Pampena, R | 1 |
| Cornacchia, L | 1 |
| Pellacani, G | 1 |
| Peris, K | 1 |
| Longo, C | 1 |
| Jadotte, YT | 1 |
| Schwartz, RA | 1 |
| Schmidberger, H | 1 |
| Rave-Fränk, M | 1 |
| Kim, S | 1 |
| Hille, A | 1 |
| Pradier, O | 1 |
| Hess, CF | 1 |
| Kovács, AF | 1 |
| Ghahremani, MT | 1 |
| Stefenelli, U | 1 |
| Bitter, K | 1 |
| Zide, MF | 1 |
| Sasson, Z | 1 |
| Morgan, CD | 1 |
| Wang, B | 1 |
| Thomas, G | 1 |
| MacKenzie, B | 1 |
| Platts, ME | 1 |
| Maruo, H | 1 |
| Kirihara, M | 1 |
| Hasegawa, K | 1 |
| Kawai, S | 1 |
| Tominaga, S | 1 |
| Ichikawa, T | 1 |
| Kume, S | 1 |
| Goldsmith, MA | 1 |
| Carter, SK | 1 |
| Kurka, M | 1 |
| Orfanos, CE | 1 |
| Pullmann, H | 1 |
| Epstein, E | 1 |
| Sadek, H | 1 |
| Azli, N | 1 |
| Wendling, JL | 1 |
| Cvitkovic, E | 1 |
| Rahal, M | 1 |
| Mamelle, G | 1 |
| Guillaume, JC | 2 |
| Armand, JP | 1 |
| Avril, MF | 1 |
| de Castelbajac, D | 1 |
| Prost, C | 1 |
| Revuz, J | 1 |
| Donald, PJ | 1 |
| Murín, J | 1 |
| Kasper, J | 1 |
| Danko, J | 1 |
| Cerná, M | 1 |
| Bulas, J | 1 |
| Uhliar, R | 1 |
| Gibson, LE | 1 |
| Perry, HO | 1 |
| Mayer, M | 1 |
| Colon, J | 1 |
| Couture, J | 1 |
| Deschênes, L | 1 |
| Sparwald, E | 1 |
| Müllensiefen, C | 1 |
| Lange, G | 1 |
| Slanina, I | 1 |
| The, KK | 1 |
| Kaulen-Becker, L | 1 |
| Laugier, P | 1 |
| Hunziker, N | 1 |
4 reviews available for fluorouracil and Cancer of Lip
| Article | Year |
|---|---|
Treatments of actinic cheilitis: A systematic review of the literature.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cheilitis; Combined Modality Therapy; Dermabrasion; D | 2020 |
The integration of chemotherapy into a combined modality approached to cancer therapy. V. Squamous cell cancer of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluoro | 1975 |
[Chronic lupus erythematosus and epidermoid carcinoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplati | 1990 |
Advanced malignancy in the young marijuana smoker.
Topics: Adolescent; Adult; Age Factors; Alcohol Drinking; Antineoplastic Combined Chemotherapy Protocols; Ar | 1991 |
1 trial available for fluorouracil and Cancer of Lip
| Article | Year |
|---|---|
Postoperative chemotherapy with cisplatin and 5-fluorouracil in cancer of the oral cavity and the oropharynx--long-term results.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 2003 |
15 other studies available for fluorouracil and Cancer of Lip
| Article | Year |
|---|---|
Solar cheilosis: an ominous precursor part II. Therapeutic perspectives.
Topics: Administration, Topical; Aminoquinolines; Biopsy; Carcinoma, Squamous Cell; Cheilitis; Combined Moda | 2012 |
[Radiation-induced mucositis and neutrophil granulocytes in oral mucosa].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy | 2003 |
Actinic keratosis: from the skin to the lip.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Chemexfoliation; Cryosurgery; Elec | 2008 |
5-Fluorouracil related toxic myocarditis: case reports and pathological confirmation.
Topics: Acute Disease; Adenocarcinoma; Adult; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Lip Ne | 1994 |
[Appearance of extrahepatic lesions in the superior lip and orbit of a patient with liver metastases of gastric cancer following partial response by hepatic arterial infusion chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Epirubicin; Fluo | 1998 |
[Vitamin A acid for the topical management of epithelial neoplasms. Combination with 5-fluorouracil].
Topics: Aged; Carcinoma, Basal Cell; Drug Therapy, Combination; Female; Fluorouracil; Humans; Keratosis; Leu | 1978 |
Treatment of lip keratoses (actinic cheilitis) with topical fluorouracil.
Topics: Administration, Topical; Adult; Aged; Cheilitis; Female; Fluorouracil; Humans; Keratosis; Lip Neopla | 1977 |
Treatment of advanced squamous cell carcinoma of the skin with cisplatin, 5-fluorouracil, and bleomycin.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma | 1990 |
[The development of myocardial infarct in a patient treated with 5-fluorouracil].
Topics: Adult; Electrocardiography; Fluorouracil; Humans; Lip Neoplasms; Male; Myocardial Infarction | 1989 |
Skin lesions from sun exposure: a treatment guide.
Topics: Acute Disease; Adult; Aged; Carcinoma, Squamous Cell; Cheilitis; Chronic Disease; Fluorouracil; Huma | 1985 |
[Chemotherapy by intra-arterial path in cancer of the "head and neck" region].
Topics: Antineoplastic Agents; Bleomycin; Facial Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Hum | 1971 |
Intra-arterial infusion--an adjuvant to the treatment of oral carcinoma.
Topics: Adult; Aged; Carotid Artery, External; Catheterization; Evaluation Studies as Topic; Floxuridine; Fl | 1972 |
[Clinical results after synchronised radiotherapy in 21 cases of human malignomas (author's transl)].
Topics: Adult; Aged; Facial Neoplasms; Female; Fluorouracil; Follow-Up Studies; Germany, West; Humans; Laryn | 1974 |
[Oral, florid papillomatosis].
Topics: Adrenal Cortex Hormones; Aged; Female; Fluorouracil; Humans; Injections, Intramuscular; Lip Neoplasm | 1973 |
[Treatment of skin cancer].
Topics: Age Factors; Carcinoma, Basal Cell; Female; Fluorouracil; Humans; Lip Neoplasms; Male; Melanoma; Pro | 1971 |