fluorouracil has been researched along with Cancer of Jejunum in 21 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To present our clinical experience of 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen administered as an adjuvant chemotherapy to 2 patients with advanced jejunal adenocarcinoma." | 7.74 | Oxaliplatin/5-fluorouracil/leucovorin (FOLFOX4) regimen as an adjuvant chemotherapy in the treatment of advanced jejunal adenocarcinoma: a report of 2 cases. ( Chen, CW; Hsieh, JS; Su, YC; Wang, JY; Wang, WM; Wu, JY, 2008) |
| "This study aimed at assessing the efficacy and safety of biweekly oxaliplatin in combination with continuous infusional 5-fluorouracil and leucovorin (modified FOLFOX regimen) in patients with advanced small bowel adenocarcinoma (SBA)." | 5.16 | A phase II study of modified FOLFOX as first-line chemotherapy in advanced small bowel adenocarcinoma. ( Feng, M; Liu, YW; Qiu, F; Xiang, XJ; Xiong, JP; Yan, J; Yu, F; Zhan, ZY; Zhang, L; Zhao, JG, 2012) |
| "To present our clinical experience of 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen administered as an adjuvant chemotherapy to 2 patients with advanced jejunal adenocarcinoma." | 3.74 | Oxaliplatin/5-fluorouracil/leucovorin (FOLFOX4) regimen as an adjuvant chemotherapy in the treatment of advanced jejunal adenocarcinoma: a report of 2 cases. ( Chen, CW; Hsieh, JS; Su, YC; Wang, JY; Wang, WM; Wu, JY, 2008) |
| "We diagnosed recurrence of jejunal carcinoma in the ileum and right ovary." | 1.43 | [Recurrence of Jejunal Carcinoma in the Ileum and Ovary - A Case Report]. ( Doki, Y; Haraguchi, N; Hata, T; Kudo, T; Matsuda, C; Mizushima, T; Mori, M; Nishimura, J; Ohara, N; Satoh, T; Takahashi, H; Yamamoto, H, 2016) |
| "Biopsied lung tumor was diagnosed as tubular adenocarcinoma, and CK7(+)/CK20(+)/Cdx-2(-)." | 1.36 | Double primary adenocarcinomas of the jejunum and descending colon with lung metastases presenting rare immunohistochemical phenotypes: a case report. ( Arai, M; Asakage, M; Endo, J; Furukawa, Y; Muto, Y; Nozawa, H; Oka, T; Yamada, Y, 2010) |
| "Final diagnosis of a pleomorphic liposarcoma was made by the routine histology and further identified by Oil Red O stain." | 1.35 | Mesojejunoileac liposarcoma with intrahepatic metastasis in a dog. ( Chang, SC; Liao, JW, 2008) |
| " Resection of liver metastases from SBA combined with neoadjuvant and adjuvant chemotherapy can result in extended disease-free survival and should undergo further investigation." | 1.33 | Resection of small bowel adenocarcinoma liver metastasis combined with neoadjuvant and adjuvant chemotherapy results in extended disease-free period--a case report. ( Eigenbrod, T; Klebl, F; Kullmann, F, 2006) |
| "The VIPoma syndrome is rare." | 1.31 | Metastatic jejunal VIPoma: beneficial effect of combination therapy with interferon-alpha and 5-fluorouracil. ( Barbier, JP; Berger, A; Carnot, F; Cellier, C; Cuillerier, E; Haddad, C; Landi, B; Siauve, N; Yaghi, C, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 12 (57.14) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Yamano, T | 1 |
| Kubo, S | 1 |
| Tomita, N | 1 |
| Li, J | 1 |
| Wang, Z | 1 |
| Liu, N | 1 |
| Hao, J | 1 |
| Xu, X | 1 |
| Kim, SH | 1 |
| Park, BS | 1 |
| Kim, HS | 1 |
| Kim, JH | 1 |
| Ohara, N | 1 |
| Haraguchi, N | 1 |
| Kudo, T | 1 |
| Takahashi, H | 1 |
| Nishimura, J | 1 |
| Hata, T | 1 |
| Matsuda, C | 1 |
| Satoh, T | 1 |
| Mizushima, T | 1 |
| Yamamoto, H | 1 |
| Doki, Y | 1 |
| Mori, M | 1 |
| Kondo, J | 1 |
| Maeda, Y | 1 |
| Nisimura, T | 1 |
| Nagashima, Y | 1 |
| Nagashima, A | 1 |
| Morita, K | 1 |
| Setoguchi, M | 1 |
| Sakata, K | 1 |
| Chang, SC | 1 |
| Liao, JW | 1 |
| Chen, CW | 1 |
| Wang, WM | 1 |
| Su, YC | 1 |
| Wu, JY | 1 |
| Hsieh, JS | 1 |
| Wang, JY | 1 |
| Nozawa, H | 1 |
| Yamada, Y | 1 |
| Muto, Y | 1 |
| Endo, J | 1 |
| Asakage, M | 1 |
| Oka, T | 1 |
| Furukawa, Y | 1 |
| Arai, M | 1 |
| Zaanan, A | 1 |
| Costes, L | 1 |
| Gauthier, M | 1 |
| Malka, D | 1 |
| Locher, C | 1 |
| Mitry, E | 1 |
| Tougeron, D | 1 |
| Lecomte, T | 1 |
| Gornet, JM | 1 |
| Sobhani, I | 1 |
| Moulin, V | 1 |
| Afchain, P | 1 |
| Taïeb, J | 1 |
| Bonnetain, F | 1 |
| Aparicio, T | 1 |
| Kim, HK | 1 |
| Ko, BM | 1 |
| Park, JK | 1 |
| Hong, SJ | 1 |
| Moon, JH | 1 |
| Lee, JS | 1 |
| Lee, MS | 1 |
| Kim, BS | 1 |
| Choda, Y | 1 |
| Ninomiya, M | 1 |
| Fujiwara, Y | 1 |
| Kanazawa, T | 1 |
| Harano, M | 1 |
| Matsukawa, H | 1 |
| Ojima, Y | 1 |
| Shiozaki, S | 1 |
| Ohno, S | 1 |
| Xiang, XJ | 1 |
| Liu, YW | 1 |
| Zhang, L | 1 |
| Qiu, F | 1 |
| Yu, F | 1 |
| Zhan, ZY | 1 |
| Feng, M | 1 |
| Yan, J | 1 |
| Zhao, JG | 1 |
| Xiong, JP | 1 |
| Inada, K | 1 |
| Maeshiro, T | 1 |
| Shida, D | 1 |
| Seyama, Y | 1 |
| Miyamoto, S | 1 |
| Inoue, S | 1 |
| Umekita, N | 1 |
| Chattopadhyay, S | 1 |
| Mondal, SK | 1 |
| Saha, A | 1 |
| Manna, A | 1 |
| Kundu, SK | 1 |
| Fukunaga, H | 1 |
| Endo, W | 1 |
| Ota, H | 1 |
| Yoshioka, S | 1 |
| Hojo, S | 1 |
| Fujie, Y | 1 |
| Yoshioka, A | 1 |
| Toyoda, Y | 1 |
| Shimizu, K | 1 |
| Maeura, Y | 1 |
| Innis, M | 1 |
| Sandiford, N | 1 |
| Shenoy, RK | 1 |
| Prussia, PR | 1 |
| Zbar, A | 1 |
| Eigenbrod, T | 1 |
| Kullmann, F | 1 |
| Klebl, F | 1 |
| Borchard, F | 1 |
| Cellier, C | 1 |
| Yaghi, C | 1 |
| Cuillerier, E | 1 |
| Siauve, N | 1 |
| Berger, A | 1 |
| Carnot, F | 1 |
| Haddad, C | 1 |
| Barbier, JP | 1 |
| Landi, B | 1 |
| Marchettini, P | 1 |
| Sugarbaker, PH | 1 |
| Nio, Y | 1 |
| Imai, S | 1 |
| Shiraishi, T | 1 |
| Tsubono, M | 1 |
| Morimoto, H | 1 |
| Tseng, CC | 1 |
| Tobe, T | 1 |
4 reviews available for fluorouracil and Cancer of Jejunum
| Article | Year |
|---|---|
Small bowel adenocarcinoma of the jejunum: a case report and literature review.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Delay | 2016 |
Synchronous quintuple primary gastrointestinal tract malignancies: Case report.
Topics: Adenocarcinoma, Mucinous; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cancer | 2017 |
[The diffuse endocrine system and the carcinoids of the alimentary tract. Part I: Orthological aspects and common morphological features of the carcinoids (author's transl)].
Topics: Adrenocorticotropic Hormone; Aged; Appendiceal Neoplasms; APUD Cells; Carcinoid Tumor; Carmustine; C | 1982 |
Mucinous adenocarcinoma of the small bowel with peritoneal seeding.
Topics: Adenocarcinoma, Mucinous; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 2002 |
1 trial available for fluorouracil and Cancer of Jejunum
| Article | Year |
|---|---|
A phase II study of modified FOLFOX as first-line chemotherapy in advanced small bowel adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; | 2012 |
16 other studies available for fluorouracil and Cancer of Jejunum
| Article | Year |
|---|---|
A patient-derived xenograft and a cell line derived from it form a useful preclinical model for small bowel adenocarcinoma.
Topics: Adenocarcinoma; Aged; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols | 2020 |
[Recurrence of Jejunal Carcinoma in the Ileum and Ovary - A Case Report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colectomy; Deo | 2016 |
[A Case of Small Bowel Adenocarcinoma That Was Diagnosed and Treated using Laparoscopic Surgery].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, A | 2016 |
Mesojejunoileac liposarcoma with intrahepatic metastasis in a dog.
Topics: Animals; Capecitabine; Deoxycytidine; Dog Diseases; Dogs; Doxorubicin; Fatal Outcome; Fluorouracil; | 2008 |
Oxaliplatin/5-fluorouracil/leucovorin (FOLFOX4) regimen as an adjuvant chemotherapy in the treatment of advanced jejunal adenocarcinoma: a report of 2 cases.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female | 2008 |
Double primary adenocarcinomas of the jejunum and descending colon with lung metastases presenting rare immunohistochemical phenotypes: a case report.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, T | 2010 |
Chemotherapy of advanced small-bowel adenocarcinoma: a multicenter AGEO study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cispla | 2010 |
[A case of locally invasive obstructive jejunal cancer with curative resection after stenting and chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Endoscopy | 2010 |
[A case report of multiple adenocarcinoma in small intestine after total gastrectomy by Roux-en-Y re-construction].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Gastrectomy | 2011 |
[A case of small intestinal cancer with peritoneal metastases treated with FOLFOX regimen].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Jejunal Neoplasms; Leuc | 2012 |
Primary carcinoma of jejunum--a case report.
Topics: Adenocarcinoma; Aged; Anastomosis, Surgical; Antimetabolites, Antineoplastic; Capecitabine; Chemothe | 2012 |
[A clinical case of recurrent small intestinal cancer successfully treated with FOLFOX6].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Fluorouracil; Humans; Jejunal Ne | 2012 |
Carcinoma of the jejunum with multideposit peritoneal seeding, resection and intraperitoneal chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Infusions, Par | 2005 |
Resection of small bowel adenocarcinoma liver metastasis combined with neoadjuvant and adjuvant chemotherapy results in extended disease-free period--a case report.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, A | 2006 |
Metastatic jejunal VIPoma: beneficial effect of combination therapy with interferon-alpha and 5-fluorouracil.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Interferon-alpha; Jejun | 2000 |
Chemosensitivity correlation between the primary tumors and simultaneous metastatic lymph nodes of patients evaluated by DNA synthesis inhibition assay.
Topics: Breast Neoplasms; Carbazilquinone; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Doxorubicin; Drug | 1990 |