Page last updated: 2024-10-27

fluorouracil and Cancer of ILEUM

fluorouracil has been researched along with Cancer of ILEUM in 16 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"We report on a series of 10 patients with carcinoid tumors metastatic to the liver who were treated with long-term octreotide acetate therapy (100 to 500 micrograms three times a day), sequential intra-arterial 5-fluorouracil (5-FU) infusions, and hepatic tumor chemoembolization."6.17Treatment of metastatic carcinoid tumors using multimodality therapy of octreotide acetate, intra-arterial chemotherapy, and hepatic arterial chemoembolization. ( Diaco, DS; Fletcher, WS; Hajarizadeh, H; Mueller, CR; Pommier, RF; Woltering, EA, 1995)
"This study aimed at assessing the efficacy and safety of biweekly oxaliplatin in combination with continuous infusional 5-fluorouracil and leucovorin (modified FOLFOX regimen) in patients with advanced small bowel adenocarcinoma (SBA)."5.16A phase II study of modified FOLFOX as first-line chemotherapy in advanced small bowel adenocarcinoma. ( Feng, M; Liu, YW; Qiu, F; Xiang, XJ; Xiong, JP; Yan, J; Yu, F; Zhan, ZY; Zhang, L; Zhao, JG, 2012)
"We diagnosed recurrence of jejunal carcinoma in the ileum and right ovary."1.43[Recurrence of Jejunal Carcinoma in the Ileum and Ovary - A Case Report]. ( Doki, Y; Haraguchi, N; Hata, T; Kudo, T; Matsuda, C; Mizushima, T; Mori, M; Nishimura, J; Ohara, N; Satoh, T; Takahashi, H; Yamamoto, H, 2016)
"Final diagnosis of a pleomorphic liposarcoma was made by the routine histology and further identified by Oil Red O stain."1.35Mesojejunoileac liposarcoma with intrahepatic metastasis in a dog. ( Chang, SC; Liao, JW, 2008)
"The most common malignancy is squamous cell carcinoma, which consists of about 75% of malignant transformations."1.35Squamous cell carcinoma arising in an ovarian mature cystic teratoma: a case report. ( Azadbakht, F; Emami-Aleagha, M; Hajarizadeh, B; Keshvari, A; Rosai, J; Sedighi, S; Shariat-Torbaghan, S, 2009)
" Resection of liver metastases from SBA combined with neoadjuvant and adjuvant chemotherapy can result in extended disease-free survival and should undergo further investigation."1.33Resection of small bowel adenocarcinoma liver metastasis combined with neoadjuvant and adjuvant chemotherapy results in extended disease-free period--a case report. ( Eigenbrod, T; Klebl, F; Kullmann, F, 2006)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's3 (18.75)18.2507
2000's6 (37.50)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ohara, N1
Haraguchi, N1
Kudo, T1
Takahashi, H1
Nishimura, J1
Hata, T2
Matsuda, C1
Satoh, T1
Mizushima, T1
Yamamoto, H1
Doki, Y1
Mori, M1
Chang, SC1
Liao, JW1
Kikuchi, M1
Kamei, S1
Morirama, Y1
Tuchiya, T1
Miwa, K1
Yokoi, S1
Nakano, M1
Ehara, H1
Deguchi, T1
Hirose, Y1
Shariat-Torbaghan, S1
Emami-Aleagha, M1
Sedighi, S1
Azadbakht, F1
Keshvari, A1
Hajarizadeh, B1
Rosai, J1
Sasaki, Y1
Natsuizaka, M1
Takano, M1
Suzuki, M1
Tsuyuguchi, M1
Nagasako, T1
Kawamura, N1
Kudo, M1
Tsuda, I1
Meguro, J1
Zaanan, A1
Costes, L1
Gauthier, M1
Malka, D1
Locher, C1
Mitry, E1
Tougeron, D1
Lecomte, T1
Gornet, JM1
Sobhani, I1
Moulin, V1
Afchain, P1
Taïeb, J1
Bonnetain, F1
Aparicio, T1
Okubo, K1
Yoshioka, S1
Asukai, K1
Nakanishi, M1
Maekawa, T1
Hama, N1
Kashiwazaki, M1
Taniguchi, M1
Tsujie, M1
Konishi, M1
Yano, K1
Fujimoto, T1
Xiang, XJ1
Liu, YW1
Zhang, L1
Qiu, F1
Yu, F1
Zhan, ZY1
Feng, M1
Yan, J1
Zhao, JG1
Xiong, JP1
Seshimo, K1
Toshima, T1
Mizuno, K1
Ikeda, H1
Kato, H1
Yamamura, M1
Kodera, M1
Oishi, M1
Yamashita, Y1
Tanaka, N1
Fujita, H1
Shibagaki, K1
Taniguchi, H1
Takeda, H1
Kobayashi, K1
Takita, K1
Nishie, M1
Iwakawa, K1
Noronha, V1
Burtness, B1
Murren, J1
Duffy, TP1
Eigenbrod, T1
Kullmann, F1
Klebl, F1
Borchard, F1
Diaco, DS1
Hajarizadeh, H1
Mueller, CR1
Fletcher, WS1
Pommier, RF1
Woltering, EA1
Barthel, A1
Leonhardt, U1
Stöckmann, F1
Ramadori, G1
Zhang, ZG1
Harstrick, A1
Rustum, YM1
Vyshinskaia, GV1
Bassalyk, LS1
Vasil'ev, SA1
Gromova, NV1
Nadezhdina, TM1

Reviews

3 reviews available for fluorouracil and Cancer of ILEUM

ArticleYear
Oxaliplatin induces a delayed immune-mediated hemolytic anemia: a case report and review of the literature.
    Clinical colorectal cancer, 2005, Volume: 5, Issue:4

    Topics: Anemia, Hemolytic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents;

2005
[The diffuse endocrine system and the carcinoids of the alimentary tract. Part I: Orthological aspects and common morphological features of the carcinoids (author's transl)].
    Zeitschrift fur Gastroenterologie, 1982, Volume: 20, Issue:4

    Topics: Adrenocorticotropic Hormone; Aged; Appendiceal Neoplasms; APUD Cells; Carcinoid Tumor; Carmustine; C

1982
Treatment of metastatic carcinoid tumors using multimodality therapy of octreotide acetate, intra-arterial chemotherapy, and hepatic arterial chemoembolization.
    American journal of surgery, 1995, Volume: 169, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Chemoembolization, Therapeuti

1995

Trials

2 trials available for fluorouracil and Cancer of ILEUM

ArticleYear
A phase II study of modified FOLFOX as first-line chemotherapy in advanced small bowel adenocarcinoma.
    Anti-cancer drugs, 2012, Volume: 23, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival;

2012
Treatment of metastatic carcinoid tumors using multimodality therapy of octreotide acetate, intra-arterial chemotherapy, and hepatic arterial chemoembolization.
    American journal of surgery, 1995, Volume: 169, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Chemoembolization, Therapeuti

1995

Other Studies

12 other studies available for fluorouracil and Cancer of ILEUM

ArticleYear
[Recurrence of Jejunal Carcinoma in the Ileum and Ovary - A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colectomy; Deo

2016
Mesojejunoileac liposarcoma with intrahepatic metastasis in a dog.
    The Journal of veterinary medical science, 2008, Volume: 70, Issue:6

    Topics: Animals; Capecitabine; Deoxycytidine; Dog Diseases; Dogs; Doxorubicin; Fatal Outcome; Fluorouracil;

2008
[Case of urachal cancer treated by neoadjuvant chemotherapy with FOLFOX4 (oxaliplatin, 5-FU and leukovolin)].
    Hinyokika kiyo. Acta urologica Japonica, 2008, Volume: 54, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Huma

2008
Squamous cell carcinoma arising in an ovarian mature cystic teratoma: a case report.
    Archives of Iranian medicine, 2009, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Che

2009
[A case of primary adenocarcinoma of small intestine with multiple liver metastases successfully treated with mFOLFOX6].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:11

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic C

2009
Chemotherapy of advanced small-bowel adenocarcinoma: a multicenter AGEO study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cispla

2010
[A case report of primary adenocarcinoma of small intestine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized;

2010
[A case of primary adenocarcinoma of small intestine responding to XELOX chemotherapy and leading to a partial metabolic response].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorou

2012
Resection of small bowel adenocarcinoma liver metastasis combined with neoadjuvant and adjuvant chemotherapy results in extended disease-free period--a case report.
    International journal of gastrointestinal cancer, 2006, Volume: 37, Issue:2-3

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, A

2006
[Individual therapeutic procedure in metastatic carcinoid of the small intestine].
    Leber, Magen, Darm, 1996, Volume: 26, Issue:3

    Topics: Carcinoid Tumor; Colectomy; Combined Modality Therapy; Female; Fluorouracil; Humans; Ileal Neoplasms

1996
Mechanisms of resistance to fluoropyrimidines.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Cecal Neoplasms; Deoxyuracil Nucleotides; Drug Resistance; Floxuridine; Fluorodeoxyuridylate; Fluoro

1992
[Clinico-biochemical findings in malignant carcinoid during cytostatic therapy (description of a case)].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Fluorouracil;

1986