fluorouracil has been researched along with Cancer of Granulosa Cells in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Even so, HCFU should be dosed when needed in spite of this risk." | 1.27 | [A case of leukoencephalopathy caused by HCFU]. ( Abe, S; Kamata, H; Kisida, S; Miyagawa, N; Murakami, A; Nagano, H; Ueda, K; Yasui, H, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Neville, AJ | 1 |
| Gilchrist, KW | 1 |
| Davis, TE | 1 |
| Yakushiji, M | 1 |
| Ide, K | 1 |
| Nishimura, H | 1 |
| Nishida, T | 1 |
| Kato, T | 1 |
| Frank, S | 1 |
| Richter, K | 1 |
| Ehrhart, H | 1 |
| Penning, W | 1 |
| Meister, P | 1 |
| Schmidt, D | 1 |
| Götz, A | 1 |
| Nakayama, T | 1 |
| Nakai, Y | 1 |
| Tamura, H | 1 |
| Nagano, T | 1 |
| Shibamoto, T | 1 |
| Ohara, A | 1 |
| Ozawa, M | 1 |
| Kurata, A | 1 |
| Kamata, H | 1 |
| Murakami, A | 1 |
| Miyagawa, N | 1 |
| Yasui, H | 1 |
| Nagano, H | 1 |
| Abe, S | 1 |
| Ueda, K | 1 |
| Kisida, S | 1 |
| Malkasian, GD | 1 |
| Webb, MJ | 1 |
| Jorgensen, EO | 1 |
6 other studies available for fluorouracil and Cancer of Granulosa Cells
| Article | Year |
|---|---|
The chemotherapy of granulosa cell tumors of the ovary: experience of the Wisconsin Clinical Cancer Center.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophospha | 1984 |
Transplantation of experimental ovarian tumors and their sensitivity to carcinostatics.
Topics: Adenocarcinoma; Animals; Female; Fluorouracil; Granulosa Cell Tumor; Humans; Male; Mitomycins; Neopl | 1979 |
[1st report on programmed chemotherapy of ovarian carcinoma].
Topics: Adenocarcinoma; Antineoplastic Agents; Cyclophosphamide; Cystadenocarcinoma; Cystadenoma; Drug Thera | 1975 |
[A case of granulosa cell tumor with unusual histologic features].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Combined Modality Therapy; Cy | 1991 |
[A case of leukoencephalopathy caused by HCFU].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; B | 1988 |
Observations on chemotherapy of granulosa cell carcinomas and malignant ovarian teratomas.
Topics: Adolescent; Adult; Antineoplastic Agents; Castration; Child; Cyclophosphamide; Dactinomycin; Fallopi | 1974 |