fluorouracil has been researched along with Cancer, Embryonal in 8 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Capecitabine was well tolerated, but is not effective in heavily pretreated patients with cisplatin-refractory or relapsed germ cell tumors." | 2.73 | An open-label, multicenter phase II trial of capecitabine in patients with cisplatin-refractory or relapsed germ cell tumors. ( Bokemeyer, C; Grünwald, V; Hartmann, JT; Honecker, F; Kollmannsberger, C; Mayer, F; Oechsle, K; Rick, O, 2007) |
| "Concerning penis cancer, the optimal protocols validated by a high level of evidence are missing." | 2.49 | [Chemotherapy in male external genital organs (testicular and penile cancer)]. ( Bastide, C; Bruyère, F; Deville, JL; Flechon, A; Guy, L; Karsenty, G, 2013) |
| " Both dosage and releasing time can be adjusted." | 1.27 | [Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites]. ( Himuro, H; Inoue, N; Kaetsu, I; Kitamura, K; Kubo, O; Sakairi, M; Tajika, T; Tajika, Y; Tohyama, T; Yoshida, M, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deville, JL | 1 |
| Flechon, A | 1 |
| Bruyère, F | 1 |
| Karsenty, G | 1 |
| Guy, L | 1 |
| Bastide, C | 1 |
| Oechsle, K | 1 |
| Honecker, F | 1 |
| Kollmannsberger, C | 1 |
| Rick, O | 1 |
| Grünwald, V | 1 |
| Mayer, F | 1 |
| Hartmann, JT | 1 |
| Bokemeyer, C | 1 |
| Zhou, ZT | 1 |
| Wang, JW | 1 |
| Yang, L | 1 |
| Wang, J | 1 |
| Zhang, W | 1 |
| Chavaudra, N | 1 |
| Malaise, EP | 1 |
| Grosh, WW | 1 |
| Jones, HW | 1 |
| Burnett, LS | 1 |
| Greco, FA | 1 |
| Koike, K | 1 |
| Kubo, O | 1 |
| Himuro, H | 1 |
| Inoue, N | 1 |
| Tajika, Y | 1 |
| Tajika, T | 1 |
| Tohyama, T | 1 |
| Sakairi, M | 1 |
| Yoshida, M | 1 |
| Kaetsu, I | 1 |
| Kitamura, K | 1 |
| Kühböck, J | 1 |
| Pokorny, D | 1 |
| Steinbach, K | 1 |
| Eggerth, G | 1 |
1 review available for fluorouracil and Cancer, Embryonal
| Article | Year |
|---|---|
[Chemotherapy in male external genital organs (testicular and penile cancer)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Chemotherapy, Adjuvant; Cisp | 2013 |
1 trial available for fluorouracil and Cancer, Embryonal
| Article | Year |
|---|---|
An open-label, multicenter phase II trial of capecitabine in patients with cisplatin-refractory or relapsed germ cell tumors.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blood Cell Count; Capecitabine; Cispl | 2007 |
6 other studies available for fluorouracil and Cancer, Embryonal
| Article | Year |
|---|---|
[Primary germ cell tumor in the mediastinum-report of 47 cases].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cisplatin; Combined Modali | 2006 |
In vitro incorporation of [3H]TdR in human and murine solid tumours. Influence of 5-fluorouracil and/or hyperbaric oxygen on spatial distribution of labelling.
Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Fluorouracil; Humans; Mice; Neoplasms; Neoplasms | 1979 |
Malignant mixed mesodermal tumors of the uterus and ovary treated with cisplatin-based combination chemotherapy.
Topics: Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxo | 1986 |
[Experimental combination chemotherapy with carboquone and 5-fluorouracil of human germ cell tumors transplanted into nude mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Female; Fluorouracil; Huma | 1986 |
[Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites].
Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Implants; Dysge | 1986 |
[Polychemotherapy of malignant tumors and hemoblastoses].
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Bronchial Neoplasms; Carcinom | 1968 |