fluorouracil has been researched along with Bullous Dermatoses in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nemer, KM | 1 |
| Solus, JF | 1 |
| Schaffer, A | 1 |
| Rosman, IS | 1 |
| Lee, SJ | 1 |
| Comfere, NI | 1 |
| Ikediobi, ON | 1 |
| Peters, MS | 1 |
| el-Azhary, RA | 1 |
| Gibson, LE | 1 |
| Sollitto, RB | 1 |
| Frank, W | 1 |
| Palko, MJ | 1 |
| Rogers, GS | 1 |
1 review available for fluorouracil and Bullous Dermatoses
| Article | Year |
|---|---|
Pharmacogenetics in dermatology: a patient-centered update.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineo | 2013 |
2 other studies available for fluorouracil and Bullous Dermatoses
| Article | Year |
|---|---|
Generalized pustular drug eruption caused by topical 5-fluorouracil.
Topics: Administration, Cutaneous; Aged; Antimetabolites, Antineoplastic; Drug Eruptions; Female; Fluorourac | 2017 |
An oncology patient with an erythematous papulosquamous eruption in sun-exposed areas. Inflamed actinic keratoses due to systemic chemotherapy (fluorouracil and, possibly, interferon alfa).
Topics: Colonic Neoplasms; Erythema; Fluorouracil; Humans; Interferon-alpha; Keratosis; Male; Middle Aged; S | 1994 |