fluorouracil has been researched along with Brill-Symmers Disease in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Okamoto, K | 1 |
| Ninomiya, I | 1 |
| Saito, H | 1 |
| Shimada, M | 1 |
| Yamaguchi, T | 1 |
| Terai, S | 1 |
| Moriyama, H | 1 |
| Kinoshita, J | 1 |
| Nakamura, K | 1 |
| Inaki, N | 1 |
| Cavaliere, A | 1 |
| Alberti, PF | 1 |
| Vitali, R | 1 |
| Stutzman, L | 1 |
1 trial available for fluorouracil and Brill-Symmers Disease
| Article | Year |
|---|---|
Combined radiotherapy and chemotherapy of lymphomas and other cancers.
Topics: Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Fluorouracil; Follow-Up Studies; Hematopoi | 1971 |
2 other studies available for fluorouracil and Brill-Symmers Disease
| Article | Year |
|---|---|
Usefulness of Prophylactic Administration of Pegfilgrastim for Esophageal Cancer Chemotherapy: A Single-center Retrospective Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Esophageal Neoplasms; Filgrast | 2022 |
5-Fluorouracil carcinogenesis in BALB/c mice.
Topics: Animals; Carcinogenicity Tests; Female; Fluorouracil; Injections, Intraperitoneal; Leukemia, Lymphoc | 1990 |