fluorouracil has been researched along with Brain Vascular Disorders in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with cancer commonly suffer neurologic disabilities." | 2.37 | Neurologic complications of systemic cancer. ( Patchell, RA; Posner, JB, 1985) |
| "Arterial thrombosis is also associated with multiagent chemotherapy in patients with breast cancer." | 1.28 | Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study. ( Korzun, AH; Norton, L; Perloff, M; Rice, MA; Wall, JG; Weiss, RB; Wood, WC, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wall, JG | 1 |
| Weiss, RB | 1 |
| Norton, L | 1 |
| Perloff, M | 1 |
| Rice, MA | 1 |
| Korzun, AH | 1 |
| Wood, WC | 1 |
| Patchell, RA | 1 |
| Posner, JB | 1 |
1 review available for fluorouracil and Brain Vascular Disorders
| Article | Year |
|---|---|
Neurologic complications of systemic cancer.
Topics: Arachnoid; Bacterial Infections; Brain; Brain Neoplasms; Cerebrovascular Disorders; Cisplatin; Disse | 1985 |
1 other study available for fluorouracil and Brain Vascular Disorders
| Article | Year |
|---|---|
Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Breast Neoplasms; | 1989 |