fluorouracil has been researched along with Brain Inflammation in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fatigue is the most common symptom related to cytotoxic chemotherapeutic treatment of cancer." | 1.40 | A role for orexin in cytotoxic chemotherapy-induced fatigue. ( Marks, DL; Weymann, KB; Wood, LJ; Zhu, X, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weymann, KB | 1 |
| Wood, LJ | 1 |
| Zhu, X | 1 |
| Marks, DL | 1 |
| Jansen, C | 1 |
| Miaskowski, C | 1 |
| Dodd, M | 1 |
| Dowling, G | 1 |
| Kramer, J | 1 |
1 review available for fluorouracil and Brain Inflammation
| Article | Year |
|---|---|
Potential mechanisms for chemotherapy-induced impairments in cognitive function.
Topics: Anemia; Animals; Antineoplastic Agents; Attention; Blood-Brain Barrier; Cognition Disorders; Cycloph | 2005 |
1 other study available for fluorouracil and Brain Inflammation
| Article | Year |
|---|---|
A role for orexin in cytotoxic chemotherapy-induced fatigue.
Topics: Animals; Antineoplastic Agents; Brain Stem; Cyclophosphamide; Cytotoxins; Doxorubicin; Drug Combinat | 2014 |