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fluorouracil and Brain Damage, Chronic

fluorouracil has been researched along with Brain Damage, Chronic in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsumoto, S1
Nishizawa, S1
Murakami, M1
Noma, S1
Sano, A1
Kuroda, Y1

Other Studies

1 other study available for fluorouracil and Brain Damage, Chronic

ArticleYear
Carmofur-induced leukoencephalopathy: MRI.
    Neuroradiology, 1995, Volume: 37, Issue:8

    Topics: Antineoplastic Agents; Brain; Brain Damage, Chronic; Breast Neoplasms; Chemotherapy, Adjuvant; Demye

1995