fluorouracil has been researched along with Bone Marrow Failure Disorders in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Bone Marrow Failure Disorders: Inherited or acquired diseases characterized by insufficient and/or dysplastic blood cells.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jafek, JL | 1 |
| Shakya, A | 1 |
| Tai, PY | 1 |
| Ibarra, A | 1 |
| Kim, H | 1 |
| Maddox, J | 1 |
| Chumley, J | 1 |
| Spangrude, GJ | 1 |
| Miles, RR | 1 |
| Kelley, TW | 1 |
| Tantin, D | 1 |
| Jones, M | 1 |
| Chase, J | 1 |
| Brinkmeier, M | 1 |
| Xu, J | 1 |
| Weinberg, DN | 1 |
| Schira, J | 1 |
| Friedman, A | 1 |
| Malek, S | 1 |
| Grembecka, J | 1 |
| Cierpicki, T | 1 |
| Dou, Y | 1 |
| Camper, SA | 1 |
| Maillard, I | 1 |
2 other studies available for fluorouracil and Bone Marrow Failure Disorders
| Article | Year |
|---|---|
Transcription factor Oct1 protects against hematopoietic stress and promotes acute myeloid leukemia.
Topics: Animals; Bone Marrow; Bone Marrow Failure Disorders; CDX2 Transcription Factor; Cell Transformation, | 2019 |
Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.
Topics: Anemia, Aplastic; Animals; Animals, Newborn; Bone Marrow Diseases; Bone Marrow Failure Disorders; Bo | 2015 |