fluorouracil has been researched along with Blood Poisoning in 20 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe the effect of 5-fluorouracil (5-FU) on modulation of the disorders of proinflammatory and anti-inflammatory cytokines in the severe sepsis as a result of intra-abdominal infection in rat, and to investigate the mechanism of efficacy of 5-FU in the treatment of severe sepsis." | 7.74 | [Effect of 5-fluorouracil on modulation of immunity-associated cytokine during severe sepsis in rat]. ( Chen, XL; Lu, LJ; Xu, N, 2008) |
| "The authors present the Hungarian interim analysis and experience with the BCIRG 001 randomized, multicentric, phase III clinical trial comparing TAC (docetaxel, doxorubicin, cyclophosphamide) and FAC (5-fluorouracil, doxorubicin, cyclophosphamide) in the adjuvant treatment of node positive breast cancer patients." | 5.10 | [Hungarian experience with docetaxel combination (TAC) in the adjuvant treatment of breast cancer. Results of BCIRG 001 randomized, multicentric, phase III trial]. ( Boér, K; Juhos, E; Láng, I; Pintér, T; Szántó, J, 2003) |
| "A 71-year-old patient receiving combination chemotherapy (irinotecan, oxaliplatin and 5-fluorouracil (5-FU)) for metastatic pancreas cancer was admitted after her first cycle of chemotherapy with a severe and unexpectedly prolonged episode of neutropenic sepsis associated with pancytopenia and marked mucositis." | 3.80 | A rare cause of susceptibility to neutropenic sepsis in a patient with metastatic pancreas cancer. ( Gillmore, R; Suarez Martinez-Falero, B, 2014) |
| "To observe the effect of 5-fluorouracil (5-FU) on modulation of the disorders of proinflammatory and anti-inflammatory cytokines in the severe sepsis as a result of intra-abdominal infection in rat, and to investigate the mechanism of efficacy of 5-FU in the treatment of severe sepsis." | 3.74 | [Effect of 5-fluorouracil on modulation of immunity-associated cytokine during severe sepsis in rat]. ( Chen, XL; Lu, LJ; Xu, N, 2008) |
| "Grade 4 neutropenia was observed in one patient." | 2.71 | Phase II trial of dose-dense paclitaxel, cisplatin, 5-fluorouracil, and leucovorin with filgrastim support in patients with squamous cell carcinoma of the head and neck. ( Castellano, D; Cortés-Funes, H; Hitt, R; Jimeno, A; Millán, JM, 2004) |
| "5-fluorouracil was given at a dose of 1000 mg/m2 for 5 consecutive days and cisplatin was given on day 2 at a dose of 100 mg/m2." | 2.68 | The French experience with infusional 5-FU in gastric and pancreatic cancer. ( Ducreux, M; Rougier, P, 1996) |
| "However, the number of long-term esophageal cancer survivors has been increasing due to advances in early detection and therapy." | 1.40 | Second primary pancreatic adenocarcinoma three years after successfully treated index esophageal cancer. ( Dasanu, CA; Nandy, N, 2014) |
| "The relevant literature regarding treatment of liver cirrhosis complicated with HCC and synchronous colon Ca reveals poor and controversial outcomes." | 1.38 | How can we treat a patient with liver cirrhosis (hepatitis C virus), hepatocellular carcinoma, and synchronous colon cancer? ( Antoniou, E; Dimitroulis, D; Kostakis, A; Labadariou, A; Mantas, D; Nikitakis, N; Paraskeva, P; Smyrnis, A; Tsavaris, N; Vernicos, P, 2012) |
| "The risk of venous thromboembolism has been reported to increase when receiving bevacizumab." | 1.36 | Therapeutic significance of a D-dimer cut-off level of >3 µg/ml in colorectal cancer patients treated with standard chemotherapy plus bevacizumab. ( Doi, T; Fuse, N; Ikematsu, H; Kaneko, K; Koike, K; Kojima, T; Minashi, K; Mochizuki, S; Ohtsu, A; Tahara, M; Yano, T; Yoshino, T, 2010) |
| "Chemotherapy is 1 method for the treatment of cancer, but serious side effects can sometimes limit the dosage given." | 1.32 | Simultaneous onset of acute inflammatory response, sepsis-like symptoms and intestinal mucosal injury after cancer chemotherapy. ( Fukushima, R; Hiki, N; Kaminishi, M; Kojima, J; Mafune, K; Mimura, Y; Nomura, S; Ogawa, T; Tsuji, E, 2003) |
| "We present a patient with metastatic breast cancer treated with high-dose chemotherapy and bone marrow transplantation." | 1.29 | Clostridium septicum abscess in hepatic metastases: successful medical management. ( Ciaccia, D; Corey, GR; Peters, W; Thel, MC; Vredenburgh, JJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 6 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saridaki, Z | 1 |
| Lambrodimou, G | 1 |
| Kachris, S | 1 |
| Makrantonakis, P | 1 |
| Boukovinas, I | 1 |
| Polyzos, A | 1 |
| Anagnostopoulos, A | 1 |
| Athanasiadis, A | 1 |
| Stoltidis, D | 1 |
| Georgoulias, V | 1 |
| Souglakos, J | 1 |
| Nandy, N | 1 |
| Dasanu, CA | 1 |
| Suarez Martinez-Falero, B | 1 |
| Gillmore, R | 1 |
| Chllamma, MK | 1 |
| Cook, N | 1 |
| Dhani, NC | 1 |
| Giby, K | 1 |
| Dodd, A | 1 |
| Wang, L | 1 |
| Hedley, DW | 1 |
| Moore, MJ | 1 |
| Knox, JJ | 1 |
| Lu, LJ | 1 |
| Xu, N | 1 |
| Chen, XL | 1 |
| Mochizuki, S | 1 |
| Yoshino, T | 1 |
| Kojima, T | 1 |
| Fuse, N | 1 |
| Ikematsu, H | 1 |
| Minashi, K | 1 |
| Yano, T | 1 |
| Tahara, M | 1 |
| Kaneko, K | 1 |
| Doi, T | 1 |
| Koike, K | 1 |
| Ohtsu, A | 1 |
| Antoniou, E | 1 |
| Mantas, D | 1 |
| Paraskeva, P | 1 |
| Dimitroulis, D | 1 |
| Smyrnis, A | 1 |
| Nikitakis, N | 1 |
| Labadariou, A | 1 |
| Tsavaris, N | 1 |
| Vernicos, P | 1 |
| Kostakis, A | 1 |
| Magnin, V | 1 |
| Moutardier, V | 1 |
| Giovannini, MH | 1 |
| Lelong, B | 1 |
| Giovannini, M | 1 |
| Viret, F | 1 |
| Monges, G | 1 |
| Bardou, VJ | 1 |
| Alzieu, C | 1 |
| Delpero, JR | 1 |
| Tsuji, E | 1 |
| Hiki, N | 1 |
| Nomura, S | 1 |
| Fukushima, R | 1 |
| Kojima, J | 1 |
| Ogawa, T | 1 |
| Mafune, K | 1 |
| Mimura, Y | 1 |
| Kaminishi, M | 1 |
| Boér, K | 1 |
| Láng, I | 1 |
| Juhos, E | 1 |
| Pintér, T | 1 |
| Szántó, J | 1 |
| CHANG, WW | 1 |
| BUERGER, L | 1 |
| MCCAFFERY, JF | 1 |
| Hitt, R | 1 |
| Jimeno, A | 1 |
| Millán, JM | 1 |
| Castellano, D | 1 |
| Cortés-Funes, H | 1 |
| Ahluwalia, MS | 1 |
| Daw, HA | 1 |
| Thel, MC | 1 |
| Ciaccia, D | 1 |
| Vredenburgh, JJ | 1 |
| Peters, W | 1 |
| Corey, GR | 1 |
| Minsky, BD | 1 |
| Neuberg, D | 1 |
| Kelsen, DP | 1 |
| Pisansky, TM | 1 |
| Ginsberg, R | 1 |
| Benson, A | 1 |
| Ducreux, M | 1 |
| Rougier, P | 1 |
| Au, E | 1 |
| Koo, WH | 1 |
| Lee, KS | 1 |
| Chua, EJ | 1 |
| Soo, KC | 1 |
| Seow-Choen, F | 1 |
| Low, CH | 1 |
| Ng, BK | 1 |
| Hoe, M | 1 |
| Farndon, JR | 1 |
| Hermann, J | 1 |
| Plenert, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Definitive Concurrent Chemoradiotherapy With Docetaxel Plus Cisplatin Versus 5-fluorouracil Plus Cisplatin in Patients With Esophageal Squamous Cell Carcinoma: a Phase II Randomized Controlled Trial[NCT02969473] | Phase 2 | 120 participants (Anticipated) | Interventional | 2010-10-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fluorouracil and Blood Poisoning
| Article | Year |
|---|---|
[Generalized candida mycoses].
Topics: Amphotericin B; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Burns; Candida albicans; Candidi | 1974 |
5 trials available for fluorouracil and Blood Poisoning
| Article | Year |
|---|---|
Neoadjuvant preoperative chemoradiation in patients with pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Mod | 2003 |
[Hungarian experience with docetaxel combination (TAC) in the adjuvant treatment of breast cancer. Results of BCIRG 001 randomized, multicentric, phase III trial].
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brea | 2003 |
Phase II trial of dose-dense paclitaxel, cisplatin, 5-fluorouracil, and leucovorin with filgrastim support in patients with squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dr | 2004 |
Neoadjuvant chemotherapy plus concurrent chemotherapy and high-dose radiation for squamous cell carcinoma of the esophagus: a preliminary analysis of the phase II intergroup trial 0122.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 1996 |
The French experience with infusional 5-FU in gastric and pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bio | 1996 |
14 other studies available for fluorouracil and Blood Poisoning
| Article | Year |
|---|---|
Postoperative treatment with docetaxel, cisplatin, and capecitabine (DCX) and chemoradiotherapy (CRT) with capecitabine for resected gastric adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; C | 2015 |
Second primary pancreatic adenocarcinoma three years after successfully treated index esophageal cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Ad | 2014 |
A rare cause of susceptibility to neutropenic sepsis in a patient with metastatic pancreas cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy-Ind | 2014 |
FOLFIRINOX for advanced pancreatic cancer: the Princess Margaret Cancer Centre experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; CA-19-9 Antigen; Cam | 2016 |
[Effect of 5-fluorouracil on modulation of immunity-associated cytokine during severe sepsis in rat].
Topics: Animals; Cytokines; Disease Models, Animal; Female; Fluorouracil; Interleukin-10; Interleukin-6; Lun | 2008 |
Therapeutic significance of a D-dimer cut-off level of >3 µg/ml in colorectal cancer patients treated with standard chemotherapy plus bevacizumab.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplast | 2010 |
How can we treat a patient with liver cirrhosis (hepatitis C virus), hepatocellular carcinoma, and synchronous colon cancer?
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Hepatocellular; Chemotherapy, Adj | 2012 |
Simultaneous onset of acute inflammatory response, sepsis-like symptoms and intestinal mucosal injury after cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Bacteria; Bacterial Infections; Bacterial Translocation; Digestive S | 2003 |
DISSEMINATED GEOTRICHOSIS; CASE REPORT.
Topics: Adenocarcinoma; Aged; Colitis; Colonic Neoplasms; Fluorouracil; Geotrichosis; Humans; Mycoses; Patho | 1964 |
STUDIES IN THE TOXICITY AND CLINICAL APPLICATION OF 5-FLUOROURACIL.
Topics: Adenocarcinoma; Agranulocytosis; Biomedical Research; Diarrhea; Diverticulitis; Drug Eruptions; Fluo | 1964 |
Adjuvant docetaxel for node-positive breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosp | 2005 |
Clostridium septicum abscess in hepatic metastases: successful medical management.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms | 1994 |
Adjuvant postoperative 5-fluorouracil chemotherapy combined with pelvic radiation for rectal cancer: results from an Asian population.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Agranulocytosis; Antimetabolites, Antineoplastic; Ch | 2001 |
The carcinoid syndrome: methods of treatment and recent experience with hepatic artery ligation and infusion.
Topics: Female; Fluorouracil; Heart Failure; Hepatic Artery; Humans; Hydroxyindoleacetic Acid; Ileum; Intest | 1977 |