fluorouracil has been researched along with Blood Platelet Disorders in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Blood Platelet Disorders: Disorders caused by abnormalities in platelet count or function.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| EISMAN, SG | 1 |
| RICHARDSON, FM | 1 |
| Shiu, MH | 1 |
| Fortner, JG | 1 |
| Cedermark, BJ | 1 |
| Didolkar, MS | 1 |
| Elias, EG | 1 |
| Gynn, TN | 1 |
| Messmore, HL | 1 |
| Friedman, IA | 1 |
| Piro, AJ | 1 |
| Wilson, RE | 1 |
| Hall, TC | 1 |
| Aliapoulios, MA | 1 |
| Nevinny, HB | 1 |
| Moore, FD | 1 |
1 review available for fluorouracil and Blood Platelet Disorders
| Article | Year |
|---|---|
Drug-induced thrombocytopenia.
Topics: Aged; Agglutination Tests; Alkaloids; Alkylating Agents; Anti-Bacterial Agents; Anticonvulsants; Ant | 1972 |
1 trial available for fluorouracil and Blood Platelet Disorders
| Article | Year |
|---|---|
Methyl-CCNU (NSC-95441) in advanced colorectal carcinoma after failure of 5-fluorouracil (NSC-19893) therapy.
Topics: Adenocarcinoma; Adult; Aged; Blood Platelet Disorders; Clinical Trials as Topic; Colonic Neoplasms; | 1976 |
3 other studies available for fluorouracil and Blood Platelet Disorders
| Article | Year |
|---|---|
CANCER CHEMOTHERAPY.
Topics: Adrenal Cortex Hormones; Aminopterin; Androgens; Antimetabolites; Antineoplastic Agents; Blood Plate | 1964 |
Current management of hepatic tumors.
Topics: Angiography; Biopsy, Needle; Blood Platelet Disorders; Carcinoma, Hepatocellular; Child; Child, Pres | 1975 |
Toxicity studies of fluorouracil used with adrenalectomy in breast cancer.
Topics: Adrenalectomy; Adult; Aged; Alopecia; Ataxia; Blood Platelet Disorders; Breast Neoplasms; Diarrhea; | 1972 |