Page last updated: 2024-10-27

fluorouracil and Blood Loss, Surgical

fluorouracil has been researched along with Blood Loss, Surgical in 10 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Blood Loss, Surgical: Loss of blood during a surgical procedure.

Research Excerpts

ExcerptRelevanceReference
"In order to determine whether preresectional chemoradiotherapy (CTRT) would influence resectability, local control, and survival of patients with localized pancreatic adenocarcinoma, a 5 1/2-year prospective study of 39 patients treated with preoperative radiation therapy, 5-Fluorouracil (5-FU), and Mitomycin C has been performed."3.68A single institutional experience with preoperative chemoradiotherapy for stage I-III pancreatic adenocarcinoma. ( Agarwal, P; Eisenberg, BL; Engstrom, P; Hoffman, JP; Litwin, S; Paul, AR; Scher, R; Solin, LJ; Watts, P; Weese, JL, 1993)
"Peritoneal carcinomatosis (PC), which has hitherto been regarded as a lethal entity, can now be cured with surgery (treating macroscopic tumor seeding) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) (treating residual microscopic disease)."2.73Optimization of hyperthermic intraperitoneal chemotherapy with oxaliplatin plus irinotecan at 43 degrees C after compete cytoreductive surgery: mortality and morbidity in 106 consecutive patients. ( Billard, V; Blot, F; Elias, D; Goere, D; Kohneh-Shahri, N; Pocard, M; Raynard, B, 2007)
"We examined the outcomes of transanal endoscopic microsurgery excisions with entry into the peritoneal cavity and compared them with those that did not to address our hypothesis that entry is safe with no ill infectious or oncological consequences."1.40Transanal endoscopic microsurgery with entrance into the peritoneal cavity: is it safe? ( D'Andrea, AP; Frenkel, JL; Greenleaf, CE; Marks, JH, 2014)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marks, JH1
Frenkel, JL1
Greenleaf, CE1
D'Andrea, AP1
Patyutko, YI1
Kotelnikov, AG1
Mamontov, KG1
Podluzhny, DV1
Ponomarenko, AA1
Troisi, RI1
Van Huysse, J1
Berrevoet, F1
Vandenbossche, B1
Sainz-Barriga, M1
Vinci, A1
Ricciardi, S1
Bocchetti, T1
Rogiers, X1
de Hemptinne, B1
Katz, MH1
Wang, H1
Balachandran, A1
Bhosale, P1
Crane, CH1
Wang, X1
Pisters, PW1
Lee, JE1
Vauthey, JN1
Abdalla, EK1
Wolff, R1
Abbruzzese, J1
Varadhachary, G1
Chopin-Laly, X1
Charnsangavej, C1
Fleming, JB1
Parameswaran, R1
Titcomb, DR1
Blencowe, NS1
Berrisford, RG1
Wajed, SA1
Streets, CG1
Hollowood, AD1
Krysztopik, R1
Barham, CP1
Blazeby, JM1
Elias, D1
Goere, D1
Blot, F1
Billard, V1
Pocard, M1
Kohneh-Shahri, N1
Raynard, B1
Hoffman, JP1
Weese, JL1
Solin, LJ1
Agarwal, P1
Engstrom, P1
Scher, R1
Paul, AR1
Litwin, S1
Watts, P1
Eisenberg, BL1
Macchiarini, P1
Chapelier, AR1
Monnet, I1
Vannetzel, JM1
Rebischung, JL1
Cerrina, J1
Parquin, F1
Ladurie, FL1
Lenot, B1
Dartevelle, PG1
Liu, FL1
Yie, QF1
Yang, CY1
Zhao, CL1
Dai, ZB1
Sugarbaker, PH1

Trials

3 trials available for fluorouracil and Blood Loss, Surgical

ArticleYear
[HEMIHEPATECTOMY FOR RESECTABLE HEPATIC METASTASIS FROM COLORECTAL CANCER WITH POOR PROGNOSIS].
    Voprosy onkologii, 2015, Volume: 61, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2015
Assessment and comparison of recovery after open and minimally invasive esophagectomy for cancer: an exploratory study in two centers.
    Annals of surgical oncology, 2013, Volume: 20, Issue:6

    Topics: Activities of Daily Living; Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemoth

2013
Optimization of hyperthermic intraperitoneal chemotherapy with oxaliplatin plus irinotecan at 43 degrees C after compete cytoreductive surgery: mortality and morbidity in 106 consecutive patients.
    Annals of surgical oncology, 2007, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agen

2007

Other Studies

7 other studies available for fluorouracil and Blood Loss, Surgical

ArticleYear
Transanal endoscopic microsurgery with entrance into the peritoneal cavity: is it safe?
    Diseases of the colon and rectum, 2014, Volume: 57, Issue:10

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Blood Loss, Su

2014
Evolution of laparoscopic left lateral sectionectomy without the Pringle maneuver: through resection of benign and malignant tumors to living liver donation.
    Surgical endoscopy, 2011, Volume: 25, Issue:1

    Topics: Adenocarcinoma; Adenoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Loss, Su

2011
Effect of neoadjuvant chemoradiation and surgical technique on recurrence of localized pancreatic cancer.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012, Volume: 16, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Blood Loss, Surgical; Capecit

2012
A single institutional experience with preoperative chemoradiotherapy for stage I-III pancreatic adenocarcinoma.
    The American surgeon, 1993, Volume: 59, Issue:11

    Topics: Adenocarcinoma; Aged; Angiography; Antineoplastic Combined Chemotherapy Protocols; Blood Loss, Surgi

1993
Extended operations after induction therapy for stage IIIb (T4) non-small cell lung cancer.
    The Annals of thoracic surgery, 1994, Volume: 57, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Loss, Surgical; Carcinoma, Non-Sm

1994
Application of anticancer agent embolism in Miles' operation.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1995, Volume: 15, Issue:3

    Topics: Adult; Blood Loss, Surgical; Chemoembolization, Therapeutic; Combined Modality Therapy; Female; Fluo

1995
Cytoreduction including total gastrectomy for pseudomyxoma peritonei.
    The British journal of surgery, 2002, Volume: 89, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Bile; Blood Loss, Surgical; Combined Modality Therapy;

2002