fluorouracil has been researched along with Blood Loss, Surgical in 10 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Blood Loss, Surgical: Loss of blood during a surgical procedure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to determine whether preresectional chemoradiotherapy (CTRT) would influence resectability, local control, and survival of patients with localized pancreatic adenocarcinoma, a 5 1/2-year prospective study of 39 patients treated with preoperative radiation therapy, 5-Fluorouracil (5-FU), and Mitomycin C has been performed." | 3.68 | A single institutional experience with preoperative chemoradiotherapy for stage I-III pancreatic adenocarcinoma. ( Agarwal, P; Eisenberg, BL; Engstrom, P; Hoffman, JP; Litwin, S; Paul, AR; Scher, R; Solin, LJ; Watts, P; Weese, JL, 1993) |
| "Peritoneal carcinomatosis (PC), which has hitherto been regarded as a lethal entity, can now be cured with surgery (treating macroscopic tumor seeding) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) (treating residual microscopic disease)." | 2.73 | Optimization of hyperthermic intraperitoneal chemotherapy with oxaliplatin plus irinotecan at 43 degrees C after compete cytoreductive surgery: mortality and morbidity in 106 consecutive patients. ( Billard, V; Blot, F; Elias, D; Goere, D; Kohneh-Shahri, N; Pocard, M; Raynard, B, 2007) |
| "We examined the outcomes of transanal endoscopic microsurgery excisions with entry into the peritoneal cavity and compared them with those that did not to address our hypothesis that entry is safe with no ill infectious or oncological consequences." | 1.40 | Transanal endoscopic microsurgery with entrance into the peritoneal cavity: is it safe? ( D'Andrea, AP; Frenkel, JL; Greenleaf, CE; Marks, JH, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marks, JH | 1 |
| Frenkel, JL | 1 |
| Greenleaf, CE | 1 |
| D'Andrea, AP | 1 |
| Patyutko, YI | 1 |
| Kotelnikov, AG | 1 |
| Mamontov, KG | 1 |
| Podluzhny, DV | 1 |
| Ponomarenko, AA | 1 |
| Troisi, RI | 1 |
| Van Huysse, J | 1 |
| Berrevoet, F | 1 |
| Vandenbossche, B | 1 |
| Sainz-Barriga, M | 1 |
| Vinci, A | 1 |
| Ricciardi, S | 1 |
| Bocchetti, T | 1 |
| Rogiers, X | 1 |
| de Hemptinne, B | 1 |
| Katz, MH | 1 |
| Wang, H | 1 |
| Balachandran, A | 1 |
| Bhosale, P | 1 |
| Crane, CH | 1 |
| Wang, X | 1 |
| Pisters, PW | 1 |
| Lee, JE | 1 |
| Vauthey, JN | 1 |
| Abdalla, EK | 1 |
| Wolff, R | 1 |
| Abbruzzese, J | 1 |
| Varadhachary, G | 1 |
| Chopin-Laly, X | 1 |
| Charnsangavej, C | 1 |
| Fleming, JB | 1 |
| Parameswaran, R | 1 |
| Titcomb, DR | 1 |
| Blencowe, NS | 1 |
| Berrisford, RG | 1 |
| Wajed, SA | 1 |
| Streets, CG | 1 |
| Hollowood, AD | 1 |
| Krysztopik, R | 1 |
| Barham, CP | 1 |
| Blazeby, JM | 1 |
| Elias, D | 1 |
| Goere, D | 1 |
| Blot, F | 1 |
| Billard, V | 1 |
| Pocard, M | 1 |
| Kohneh-Shahri, N | 1 |
| Raynard, B | 1 |
| Hoffman, JP | 1 |
| Weese, JL | 1 |
| Solin, LJ | 1 |
| Agarwal, P | 1 |
| Engstrom, P | 1 |
| Scher, R | 1 |
| Paul, AR | 1 |
| Litwin, S | 1 |
| Watts, P | 1 |
| Eisenberg, BL | 1 |
| Macchiarini, P | 1 |
| Chapelier, AR | 1 |
| Monnet, I | 1 |
| Vannetzel, JM | 1 |
| Rebischung, JL | 1 |
| Cerrina, J | 1 |
| Parquin, F | 1 |
| Ladurie, FL | 1 |
| Lenot, B | 1 |
| Dartevelle, PG | 1 |
| Liu, FL | 1 |
| Yie, QF | 1 |
| Yang, CY | 1 |
| Zhao, CL | 1 |
| Dai, ZB | 1 |
| Sugarbaker, PH | 1 |
3 trials available for fluorouracil and Blood Loss, Surgical
| Article | Year |
|---|---|
[HEMIHEPATECTOMY FOR RESECTABLE HEPATIC METASTASIS FROM COLORECTAL CANCER WITH POOR PROGNOSIS].
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva | 2015 |
Assessment and comparison of recovery after open and minimally invasive esophagectomy for cancer: an exploratory study in two centers.
Topics: Activities of Daily Living; Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemoth | 2013 |
Optimization of hyperthermic intraperitoneal chemotherapy with oxaliplatin plus irinotecan at 43 degrees C after compete cytoreductive surgery: mortality and morbidity in 106 consecutive patients.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agen | 2007 |
7 other studies available for fluorouracil and Blood Loss, Surgical
| Article | Year |
|---|---|
Transanal endoscopic microsurgery with entrance into the peritoneal cavity: is it safe?
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Blood Loss, Su | 2014 |
Evolution of laparoscopic left lateral sectionectomy without the Pringle maneuver: through resection of benign and malignant tumors to living liver donation.
Topics: Adenocarcinoma; Adenoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Loss, Su | 2011 |
Effect of neoadjuvant chemoradiation and surgical technique on recurrence of localized pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Blood Loss, Surgical; Capecit | 2012 |
A single institutional experience with preoperative chemoradiotherapy for stage I-III pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Aged; Angiography; Antineoplastic Combined Chemotherapy Protocols; Blood Loss, Surgi | 1993 |
Extended operations after induction therapy for stage IIIb (T4) non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Loss, Surgical; Carcinoma, Non-Sm | 1994 |
Application of anticancer agent embolism in Miles' operation.
Topics: Adult; Blood Loss, Surgical; Chemoembolization, Therapeutic; Combined Modality Therapy; Female; Fluo | 1995 |
Cytoreduction including total gastrectomy for pseudomyxoma peritonei.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Bile; Blood Loss, Surgical; Combined Modality Therapy; | 2002 |