fluorouracil has been researched along with Blood Coagulation Disorders in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Blood Coagulation Disorders: Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 18 colorectal cancer patients who received bevacizumab combined with chemotherapy were included." | 1.38 | Evaluating coagulation disorders in the use of bevacizumab for metastatic colorectal cancer by thrombelastography. ( Akay, OM; Bal, C; Gulbas, Z; Keskin, M; Kuş, E; Ustuner, Z, 2012) |
| " Twelve were on an average warfarin dosage of 19." | 1.33 | A retrospective study of coagulation abnormalities in patients receiving concomitant capecitabine and warfarin. ( Diasio, R; Ledbetter, L; Saif, MW; Shah, HR, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ustuner, Z | 1 |
| Akay, OM | 1 |
| Keskin, M | 1 |
| Kuş, E | 1 |
| Bal, C | 1 |
| Gulbas, Z | 1 |
| Shah, HR | 1 |
| Ledbetter, L | 1 |
| Diasio, R | 1 |
| Saif, MW | 1 |
2 other studies available for fluorouracil and Blood Coagulation Disorders
| Article | Year |
|---|---|
Evaluating coagulation disorders in the use of bevacizumab for metastatic colorectal cancer by thrombelastography.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bloo | 2012 |
A retrospective study of coagulation abnormalities in patients receiving concomitant capecitabine and warfarin.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antimetabolites, Antineoplastic; Blood Coagulation D | 2006 |