fluorouracil has been researched along with Blood Clot in 72 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The patient was treated with cetuximab and 5-fluorouracil at a below-guideline dose; however, portal vein thrombosis developed and led to death." | 9.41 | Portal vein thrombosis after cetuximab and 5-fluorouracil therapy in a patient with advanced colon cancer and decompensated cirrhosis: a case report and review of the literature. ( Guo, Y; Liu, F; Nian, J; Xu, Y; Yang, G, 2023) |
| "We report a case of long-term survival of a patient with hepatocellular carcinoma( HCC) with portal vein tumor thrombus (PVTT) treated with fluorouracil arterial infusion and interferon therapy (FAIT)." | 7.79 | [Long-term survival of a patient with hepatocellular carcinoma with portal vein tumor thrombus treated with interferon-α and 5-fluorouracil combination therapy]. ( Akita, H; Doki, Y; Eguchi, H; Hama, N; Kawamoto, K; Kobayashi, S; Mori, M; Nagano, H; Tomimaru, Y; Tsuda, Y; Umeshita, K; Wada, H, 2013) |
| "Hepatic arterial infusion chemotherapy (HAIC) combined with sorafenib is considered to be a promising therapeutic strategy for patients with advanced hepatocellular carcinoma." | 7.78 | Hepatic arterial thrombosis: a critical complication during combination therapy of arterial chemoinfusion and sorafenib. ( Anai, H; Kichikawa, K; Maeda, S; Masada, T; Nishiofuku, H; Sueyoshi, S; Tanaka, T, 2012) |
| "A heparinized catheter was used for the regional infusion of 5-fluorouracil in seven patients with liver metastases." | 7.66 | Heparinized catheters for long-term intraarterial infusion of 5-fluorouracil in liver metastases. ( Forsberg, L; Owman, T; Tylén, U, 1979) |
| " The patient was treated with cetuximab and 5-fluorouracil at a below-guideline dose; however, portal vein thrombosis developed and led to death." | 5.41 | Portal vein thrombosis after cetuximab and 5-fluorouracil therapy in a patient with advanced colon cancer and decompensated cirrhosis: a case report and review of the literature. ( Guo, Y; Liu, F; Nian, J; Xu, Y; Yang, G, 2023) |
| "Between July 1999 and August 2001, 95 cancer patients were evaluated." | 5.32 | Minidose warfarin prophylaxis for catheter-associated thrombosis in cancer patients: can it be safely associated with fluorouracil-based chemotherapy? ( Carnaghi, C; Castagna, L; Fallini, M; Magagnoli, M; Masci, G; Pedicini, V; Santoro, A; Sarina, B; Zucali, PA, 2003) |
| "The purpose of this phase II study was to explore the efficacy and safety of an alternating regimen consisting of folinic acid, 5-fluorouracil (5-FU) and oxaliplatin (mFOLFOX6) plus bevacizumab, and folinic acid, 5-FU and irinotecan (FOLFIRI) plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer." | 5.22 | Phase II trial of an alternating regimen consisting of first-line mFOLFOX6 plus bevacizumab and FOLFIRI plus bevacizumab for patients with metastatic colorectal cancer: FIREFOX plus bevacizumab trial (KSCC0801). ( Akagi, Y; Emi, Y; Higashi, H; Ishikawa, H; Kusumoto, T; Maehara, Y; Matsuda, H; Miwa, K; Ogata, Y; Oki, E; Saeki, H; Samura, H; Sueyoshi, S; Tanaka, T; Tokunaga, S; Touyama, T, 2016) |
| " We performed a randomized trial comparing 12 weeks of chemohormonal therapy (using cyclophosphamide, methotrexate, fluorouracil, vincristine, prednisone, doxorubicin, and tamoxifen) with 36 weeks of chemotherapy (using cyclophosphamide, methotrexate, fluorouracil, vincristine, and prednisone) in patients with Stage II breast cancer." | 5.06 | The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer. ( Arnold, A; De Pauw, S; Gent, M; Goodyear, MD; Hirsh, J; Hryniuk, W; Levine, MN, 1988) |
| "We report a case of long-term survival of a patient who received low-dose 5-fluorouracil and cisplatin (FP) systemic chemotherapy and underwent partial resection of the lung for a tumor thrombus in the inferior caval vein (IVC) and multiple lung metastases from recurrent hepatocellular carcinoma (HCC)." | 4.90 | [A case of long-term survival after low-dose FP systemic chemotherapy for a tumor thrombus in the inferior caval vein and multiple lung metastases from recurrent hepatocellular carcinoma]. ( Akasu, I; Fukushima, G; Kataoka, H; Kondo, K; Magata, H; Marutsuka, H; Nakamura, K; Otani, K; Sato, Y; Yano, K; Yonei, A, 2014) |
| "We report a case of long-term survival of a patient with hepatocellular carcinoma( HCC) with portal vein tumor thrombus (PVTT) treated with fluorouracil arterial infusion and interferon therapy (FAIT)." | 3.79 | [Long-term survival of a patient with hepatocellular carcinoma with portal vein tumor thrombus treated with interferon-α and 5-fluorouracil combination therapy]. ( Akita, H; Doki, Y; Eguchi, H; Hama, N; Kawamoto, K; Kobayashi, S; Mori, M; Nagano, H; Tomimaru, Y; Tsuda, Y; Umeshita, K; Wada, H, 2013) |
| "Hepatic arterial infusion chemotherapy (HAIC) combined with sorafenib is considered to be a promising therapeutic strategy for patients with advanced hepatocellular carcinoma." | 3.78 | Hepatic arterial thrombosis: a critical complication during combination therapy of arterial chemoinfusion and sorafenib. ( Anai, H; Kichikawa, K; Maeda, S; Masada, T; Nishiofuku, H; Sueyoshi, S; Tanaka, T, 2012) |
| "We reported a case of large right atrial thrombus which migrated from the inferior vena cava after acute left ventricular dysfunction due to 5-Fluorouracil cardiotoxicity." | 3.74 | Right atrial thrombus from inferior vena cava after acute cardiotoxicity of 5-fluorouracil. ( Goudev, A; Kinova, E; Zlatareva, N, 2008) |
| "In a pilot study of continuous infusion 5-fluorouracil and intermittent bolus doxorubicin and cyclophosphamide in women with breast cancer, four of 24 patients developed symptomatic superior vena cava or innominate vein thrombosis associated with the Hickman line, despite prophylactic treatment with very low dose warfarin (1-3 mg/day)." | 3.69 | Successful thrombolysis of SVC thrombosis associated with Hickman lines and continuous infusion chemotherapy. ( Baxter, G; Bissett, D; Kaye, SB; Moss, J, 1996) |
| "A heparinized catheter was used for the regional infusion of 5-fluorouracil in seven patients with liver metastases." | 3.66 | Heparinized catheters for long-term intraarterial infusion of 5-fluorouracil in liver metastases. ( Forsberg, L; Owman, T; Tylén, U, 1979) |
| "We reported a patient survived more than 7years after undergoing hepatectomy accompanied by tumor thrombectomy in the main trunk of the portal vein after preoperative hepatic arterial chemotherapy for hepatocellular carcinoma combined with tumor thrombus in the main portal vein." | 1.48 | [A Case of a Long-Term Survivor Who Underwent Surgical Intervention for Hepatocellular Carcinoma Combined with Tumor Thrombus in the Main Trunkof the Portal Vein]. ( Fujisaki, S; Sakurai, K; Takashina, M; Takayama, T; Tomita, R, 2018) |
| "Metastasis of colorectal cancer (CRC) in an adrenal gland develops in 1." | 1.42 | [Epinephros metastasis of colorectal cancer complicated by tumor thrombosis of inferior vena cava]. ( Andreĭtseva, OI; Gritsiuta, AI; Kalinin, DV; Kharazov, AF; Vishnevskiĭ, AV; Zhavoronkova, OI, 2015) |
| "A 44-year-old man with advanced hepatocellular carcinoma (HCC) was admitted to our institution." | 1.39 | [A case of hepatocellular carcinoma (Vp4)-combination therapy prolonged survival in a patient with advanced hepatocellular carcinoma with a tumor thrombus in the portal vein trunk]. ( Kanbara, Y; Tai, K; Terai, S, 2013) |
| " Adverse events were assessed by the National Cancer Institute Common Terminology Criteria for Adverse Events." | 1.37 | Retrospective cohort study on the safety and efficacy of bevacizumab with chemotherapy for metastatic colorectal cancer patients: the HGCSG0801 study. ( Asaka, M; Hatanaka, K; Hosokawa, A; Iwanaga, I; Kato, T; Komatsu, Y; Kusumi, T; Miyagishima, T; Nakamura, M; Sakata, Y; Sogabe, S; Yuki, S, 2011) |
| "Thrombosis is a common complication for breast cancer patients receiving chemotherapy." | 1.37 | Breast cancer chemotherapy induces the release of cell-free DNA, a novel procoagulant stimulus. ( Liaw, PC; Mukherjee, S; Swystun, LL, 2011) |
| "Between July 1999 and August 2001, 95 cancer patients were evaluated." | 1.32 | Minidose warfarin prophylaxis for catheter-associated thrombosis in cancer patients: can it be safely associated with fluorouracil-based chemotherapy? ( Carnaghi, C; Castagna, L; Fallini, M; Magagnoli, M; Masci, G; Pedicini, V; Santoro, A; Sarina, B; Zucali, PA, 2003) |
| "Probucol is a lipid-lowering drug with strong antioxidant properties." | 1.32 | Effects of probucol on endothelial damage by 5-fluorouracil. ( Albertsson, M; Cwikiel, M; Eskilsson, J; Kinhult, S, 2003) |
| "Nineteen patients with far advanced hepatocellular carcinoma received transarterial hepatic chemotherapy." | 1.32 | [Long-term outcome of advanced hepatocellular carcinoma that received transarterial hepatic chemotherapy]. ( Furukawa, H; Imamura, H; Inoue, Y; Ishida, H; Kitamura, S; Masuda, F; Masutani, S; Obana, T; Ohnishi, H; Saeki, N; Shimizu, J; Takamura, M; Tatsuta, M; Tomotsu, K; Yura, M, 2003) |
| "Methylene blue injection was used to identify anomalous arterial anatomy, which was found in 26 of 95 patients (27%), and significant extrahepatic 'access', which was seen in 25 patients (26%) after initial placement." | 1.31 | Hepatic artery access ports: recognizing and avoiding the problems. ( Cannan, RJ; Stubbs, RS; Wickremesekera, JK, 2000) |
| "If hepatic reserve is satisfactory, an aggressive surgical approach combined with chemotherapy seems to be of benefit for patients having HCC with tumor thrombus in the MPV, IVC, or EBD." | 1.31 | Surgical resection combined with chemotherapy for advanced hepatocellular carcinoma with tumor thrombus: report of 19 cases. ( Aoyagi, S; Eriguchi, N; Fukuda, S; Imamura, I; Imamura, M; Okuda, K, 2002) |
| "Of 23 patients, 18 had carcinoid syndrome and 19 had elevated urinary 5-hydroxyindoleacetic acid (5-HIAA) levels." | 1.29 | Transcatheter chemoembolization of progressive carcinoid liver metastasis. ( Breittmayer, F; De Baere, T; Ducreux, M; Elias, D; Indushekar, S; Lasser, P; Roche, A; Rougier, P; Therasse, E, 1993) |
| "Eighty-one cases of advanced gastric cancer, who had been treated by intra-arterial infusion chemotherapy, were examined for complications related to catheter indwelling." | 1.28 | [Complications related to catheter indwelling in intra-arterial infusion chemotherapy from the standpoint of the route of cannulation]. ( Arai, K; Kitamura, M; Miyashita, K, 1992) |
| "Presence of hepatomegaly emerged as the more significant (P = 0." | 1.28 | Prognostic factors in patients with liver metastases from colorectal carcinoma treated with discontinuous intra-arterial hepatic chemotherapy. ( Ducreux, M; Elias, D; Lasser, PH; Lumbroso, J; Pignon, JP; Rougier, P; Ruffie, P; Tigaud, JM, 1991) |
| "Arterial thrombosis is also associated with multiagent chemotherapy in patients with breast cancer." | 1.28 | Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study. ( Korzun, AH; Norton, L; Perloff, M; Rice, MA; Wall, JG; Weiss, RB; Wood, WC, 1989) |
| "Effect of this treatment on the pain could be evaluated in 16 patients." | 1.27 | Palliation of pelvic recurrence of colorectal cancer with intra-arterial 5-fluorouracil and mitomycin. ( Chuang, VP; Claghorn, L; Mavligit, G; Patt, YZ; Peters, RE; Wallace, S, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (16.67) | 18.7374 |
| 1990's | 14 (19.44) | 18.2507 |
| 2000's | 27 (37.50) | 29.6817 |
| 2010's | 16 (22.22) | 24.3611 |
| 2020's | 3 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Narita, H | 1 |
| Kawaratani, H | 1 |
| Shibamoto, A | 1 |
| Takeda, S | 1 |
| Ozutsumi, T | 1 |
| Tsuji, Y | 1 |
| Fujinaga, Y | 1 |
| Kitagawa, K | 1 |
| Nishimura, N | 1 |
| Hokuto, D | 1 |
| Sho, M | 1 |
| Yoshiji, H | 1 |
| Liu, F | 1 |
| Xu, Y | 1 |
| Yang, G | 1 |
| Guo, Y | 1 |
| Nian, J | 1 |
| White, KE | 1 |
| Elder, CT | 1 |
| Fujisaki, S | 1 |
| Takashina, M | 1 |
| Tomita, R | 1 |
| Sakurai, K | 1 |
| Takayama, T | 1 |
| Doganci, S | 1 |
| Kadan, M | 1 |
| Kaya, E | 1 |
| Erol, G | 1 |
| Gunay, C | 1 |
| Demirkilic, U | 1 |
| Robinson, SM | 1 |
| Mann, J | 1 |
| Vasilaki, A | 1 |
| Mathers, J | 1 |
| Burt, AD | 1 |
| Oakley, F | 1 |
| White, SA | 1 |
| Mann, DA | 1 |
| Olgun, DC | 1 |
| Bakan, S | 1 |
| Samanci, C | 1 |
| Tutar, O | 1 |
| Demiryas, S | 1 |
| Korkmazer, B | 1 |
| Kantarci, F | 1 |
| Tsuda, Y | 1 |
| Kobayashi, S | 1 |
| Tomimaru, Y | 1 |
| Akita, H | 1 |
| Hama, N | 1 |
| Wada, H | 1 |
| Kawamoto, K | 1 |
| Eguchi, H | 1 |
| Umeshita, K | 2 |
| Doki, Y | 1 |
| Mori, M | 1 |
| Nagano, H | 2 |
| Terai, S | 1 |
| Tai, K | 1 |
| Kanbara, Y | 1 |
| Okabe, T | 1 |
| Nakamura, M | 3 |
| Hoshino, K | 1 |
| Sunose, Y | 1 |
| Takeyoshi, I | 1 |
| Schwameis, M | 1 |
| Thaler, J | 1 |
| Schober, A | 1 |
| Schörgenhofer, C | 1 |
| Kulinna-Cosentini, C | 1 |
| Laggner, A | 1 |
| Röggla, M | 1 |
| Jilma, B | 1 |
| Magata, H | 1 |
| Kondo, K | 1 |
| Otani, K | 1 |
| Yano, K | 1 |
| Yonei, A | 1 |
| Nakamura, K | 1 |
| Akasu, I | 1 |
| Sato, Y | 1 |
| Marutsuka, H | 1 |
| Fukushima, G | 1 |
| Kataoka, H | 1 |
| Vishnevskiĭ, AV | 1 |
| Andreĭtseva, OI | 1 |
| Kharazov, AF | 1 |
| Gritsiuta, AI | 1 |
| Kalinin, DV | 1 |
| Zhavoronkova, OI | 1 |
| Miwa, K | 1 |
| Oki, E | 1 |
| Emi, Y | 1 |
| Saeki, H | 1 |
| Kusumoto, T | 1 |
| Akagi, Y | 1 |
| Ogata, Y | 1 |
| Samura, H | 1 |
| Tokunaga, S | 1 |
| Ishikawa, H | 1 |
| Tanaka, T | 2 |
| Sueyoshi, S | 2 |
| Higashi, H | 1 |
| Matsuda, H | 1 |
| Touyama, T | 1 |
| Maehara, Y | 1 |
| Kinova, E | 1 |
| Zlatareva, N | 1 |
| Goudev, A | 1 |
| Daher, IN | 1 |
| Yeh, ET | 1 |
| Sogabe, S | 1 |
| Komatsu, Y | 1 |
| Yuki, S | 1 |
| Kusumi, T | 1 |
| Hatanaka, K | 1 |
| Kato, T | 1 |
| Miyagishima, T | 1 |
| Hosokawa, A | 1 |
| Iwanaga, I | 1 |
| Sakata, Y | 1 |
| Asaka, M | 1 |
| Mukherjee, SD | 1 |
| Swystun, LL | 2 |
| Mackman, N | 1 |
| Wang, JG | 1 |
| Pond, G | 1 |
| Levine, MN | 2 |
| Liaw, PC | 2 |
| Mukherjee, S | 1 |
| Wang, PL | 1 |
| Cheng, YB | 1 |
| Kuerban, G | 1 |
| Nishiofuku, H | 1 |
| Anai, H | 1 |
| Maeda, S | 1 |
| Masada, T | 1 |
| Kichikawa, K | 1 |
| Bayne, MC | 1 |
| Barnett, KT | 1 |
| Malafa, MP | 1 |
| Masci, G | 3 |
| Magagnoli, M | 3 |
| Zucali, PA | 1 |
| Castagna, L | 3 |
| Carnaghi, C | 1 |
| Sarina, B | 1 |
| Pedicini, V | 1 |
| Fallini, M | 1 |
| Santoro, A | 3 |
| Magnin, V | 1 |
| Moutardier, V | 1 |
| Giovannini, MH | 1 |
| Lelong, B | 1 |
| Giovannini, M | 1 |
| Viret, F | 1 |
| Monges, G | 1 |
| Bardou, VJ | 1 |
| Alzieu, C | 1 |
| Delpero, JR | 1 |
| Kinhult, S | 1 |
| Albertsson, M | 1 |
| Eskilsson, J | 1 |
| Cwikiel, M | 1 |
| Kilickap, S | 1 |
| Abali, H | 1 |
| Celik, I | 1 |
| Stippel, DL | 1 |
| Töx, U | 1 |
| Gossmann, A | 1 |
| Beckurts, KT | 1 |
| Hölscher, AH | 1 |
| Masutani, S | 1 |
| Shimizu, J | 1 |
| Tatsuta, M | 1 |
| Masuda, F | 1 |
| Imamura, H | 1 |
| Ishida, H | 1 |
| Furukawa, H | 1 |
| Tomotsu, K | 1 |
| Yura, M | 1 |
| Obana, T | 1 |
| Kitamura, S | 1 |
| Saeki, N | 1 |
| Inoue, Y | 1 |
| Takamura, M | 1 |
| Ohnishi, H | 1 |
| Ota, H | 1 |
| Sakon, M | 1 |
| Yamamoto, T | 1 |
| Marubashi, S | 1 |
| Miyamoto, A | 1 |
| Dono, K | 1 |
| Nakamori, S | 1 |
| Murakami, T | 1 |
| Nakamura, H | 1 |
| Monden, M | 1 |
| Leitman, M | 1 |
| Baram, S | 1 |
| Sidenko, S | 1 |
| Abo-Kishk, I | 1 |
| Peleg, E | 1 |
| Vered, Z | 1 |
| Evans, TK | 1 |
| Phillips, HA | 1 |
| Haruno, M | 1 |
| Shimamura, R | 1 |
| Ogawa, Y | 1 |
| Tanaka, H | 1 |
| Sakai, K | 1 |
| Araki, K | 1 |
| Morenghi, E | 1 |
| Giunta, G | 1 |
| Gordon, MS | 1 |
| Cunningham, D | 1 |
| Hoff, PM | 1 |
| Ozyiğit, T | 1 |
| Buğra, Z | 1 |
| Lokich, JJ | 1 |
| Perri, J | 1 |
| Bothe, A | 1 |
| Zipoli, T | 1 |
| Philips, D | 1 |
| Sonneborn, H | 1 |
| Paul, S | 1 |
| Green, R | 1 |
| Kaetsu, I | 1 |
| Yoshida, M | 1 |
| Kumakura, M | 1 |
| Yamada, A | 1 |
| Sakurai, Y | 1 |
| Yoshida, Y | 1 |
| Egami, I | 1 |
| Onda, M | 1 |
| Therasse, E | 1 |
| Breittmayer, F | 1 |
| Roche, A | 1 |
| De Baere, T | 1 |
| Indushekar, S | 1 |
| Ducreux, M | 3 |
| Lasser, P | 2 |
| Elias, D | 3 |
| Rougier, P | 3 |
| Barberi-Heyob, M | 1 |
| Merlin, JL | 1 |
| Vigneron, M | 1 |
| Conroy, T | 1 |
| Tolcher, AW | 1 |
| Giusti, RM | 1 |
| O'Shaughnessy, JA | 1 |
| Cowan, KH | 1 |
| Theodossiou, C | 1 |
| Kroog, G | 1 |
| Ettinghausen, S | 1 |
| Tolcher, A | 1 |
| Cowan, K | 1 |
| O'Shaughnessy, J | 1 |
| Okamoto, T | 1 |
| Noguchi, Y | 1 |
| Yoshikawa, T | 1 |
| Nomura, K | 1 |
| Fukuzawa, K | 1 |
| Uranaka, Y | 1 |
| Makino, T | 1 |
| Tsuburaya, A | 1 |
| Amano, T | 1 |
| Matsumoto, A | 1 |
| Bissett, D | 1 |
| Kaye, SB | 1 |
| Baxter, G | 1 |
| Moss, J | 1 |
| Rella, C | 1 |
| Coviello, M | 1 |
| Giotta, F | 1 |
| Maiello, E | 1 |
| Colavito, P | 1 |
| Colangelo, D | 1 |
| Quaranta, M | 1 |
| Colucci, G | 1 |
| Schittulli, F | 1 |
| Ando, E | 1 |
| Yamashita, F | 1 |
| Tanaka, M | 1 |
| Tanikawa, K | 1 |
| Oberhoff, C | 1 |
| Winkler, UH | 1 |
| Tauchert, AM | 1 |
| Schindler, AE | 1 |
| Blot, E | 1 |
| Marie, I | 1 |
| Delastre, O | 1 |
| Cailleux, N | 1 |
| Pouillart, P | 1 |
| Lévesque, H | 1 |
| Courtois, H | 1 |
| Wickremesekera, JK | 1 |
| Cannan, RJ | 1 |
| Stubbs, RS | 1 |
| Mitsuyama, S | 1 |
| Anan, K | 1 |
| van Riel, JM | 1 |
| van Groeningen, CJ | 1 |
| Albers, SH | 1 |
| Cazemier, M | 1 |
| Meijer, S | 1 |
| Bleichrodt, R | 1 |
| van den Berg, FG | 1 |
| Pinedo, HM | 1 |
| Giaccone, G | 1 |
| Fiorentini, G | 1 |
| De Giorgi, U | 1 |
| Giovanis, P | 1 |
| Guadagni, S | 1 |
| Cantore, M | 1 |
| Marangolo, M | 1 |
| Sugden, EM | 1 |
| Griffiths, CL | 1 |
| Greywoode, GI | 1 |
| Lewis, SM | 1 |
| Bleiberg, H | 1 |
| Di Leo, A | 1 |
| Fukuda, S | 1 |
| Okuda, K | 1 |
| Imamura, M | 1 |
| Imamura, I | 1 |
| Eriguchi, N | 1 |
| Aoyagi, S | 1 |
| Clouse, ME | 2 |
| Ahmed, R | 1 |
| Ryan, RB | 1 |
| Oberfield, RA | 2 |
| McCaffrey, JA | 2 |
| Polio, J | 1 |
| Hamilton, T | 1 |
| Grage, TB | 1 |
| Vassilopoulos, PP | 1 |
| Shingleton, WW | 1 |
| Jubert, AV | 1 |
| Elias, EG | 1 |
| Aust, JB | 1 |
| Moss, SE | 1 |
| Tylén, U | 1 |
| Forsberg, L | 1 |
| Owman, T | 1 |
| Arai, K | 1 |
| Kitamura, M | 1 |
| Miyashita, K | 1 |
| Manheimer, F | 1 |
| Aranda, CP | 1 |
| Smith, RL | 1 |
| Pignon, JP | 1 |
| Tigaud, JM | 1 |
| Lumbroso, J | 2 |
| Ruffie, P | 1 |
| Lasser, PH | 1 |
| Wall, JG | 1 |
| Weiss, RB | 1 |
| Norton, L | 1 |
| Perloff, M | 1 |
| Rice, MA | 1 |
| Korzun, AH | 1 |
| Wood, WC | 1 |
| Ghosn, M | 1 |
| Sidibe, S | 1 |
| Droz, JP | 1 |
| Ohya, K | 1 |
| Soh, M | 1 |
| Kaneko, H | 1 |
| Kawai, T | 1 |
| Yamazaki, S | 1 |
| Iwasaki, M | 1 |
| Kameya, S | 1 |
| Patt, YZ | 1 |
| Peters, RE | 1 |
| Chuang, VP | 1 |
| Wallace, S | 1 |
| Claghorn, L | 1 |
| Mavligit, G | 1 |
| Gent, M | 1 |
| Hirsh, J | 1 |
| Arnold, A | 1 |
| Goodyear, MD | 1 |
| Hryniuk, W | 1 |
| De Pauw, S | 1 |
| Colon, J | 1 |
| Mayer, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sorafenib Alone Versus Sorafenib Combined With Hepatic Arterial Chemoinfusion for Advanced HCC With Portal Vein Tumor Thrombosis: a Multicentre Randomised Controlled Trial[NCT02774187] | Phase 3 | 247 participants (Actual) | Interventional | 2016-05-31 | Completed | ||
| Phase II Trial of Sorafenib Combined With Concurrent Hepatic Arterial Infusion (HAI) of Oxaliplatin, 5-fluorouracil and Leucovorin for Hepatocellular Carcinoma[NCT02981498] | Phase 2 | 35 participants (Anticipated) | Interventional | 2015-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for fluorouracil and Blood Clot
| Article | Year |
|---|---|
Portal vein thrombosis after cetuximab and 5-fluorouracil therapy in a patient with advanced colon cancer and decompensated cirrhosis: a case report and review of the literature.
Topics: Cetuximab; Colonic Neoplasms; Fluorouracil; Humans; Liver Cirrhosis; Liver Diseases; Portal Vein; Po | 2023 |
[A case of long-term survival after low-dose FP systemic chemotherapy for a tumor thrombus in the inferior caval vein and multiple lung metastases from recurrent hepatocellular carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Fluorour | 2014 |
Vascular complications of selected cancer therapies.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimet | 2008 |
Complications of hepatic artery infusion: a review of 4580 reported cases.
Topics: Antimetabolites, Antineoplastic; Arterial Occlusive Diseases; Bone Marrow Diseases; Catheters, Indwe | 2001 |
Successful treatment of radiofrequency-induced biliary lesions by interventional endoscopic retrograde cholangiography (ERC).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract; Carcinoma, Hepatocellula | 2003 |
Managing patients treated with bevacizumab combination therapy.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C | 2005 |
Bevacizumab in older patients and patients with poorer performance status.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C | 2006 |
Arterial thrombosis associated with granulocyte-macrophage colony-stimulating factor (GM-CSF) administration in breast cancer patients treated with dose-intensive chemotherapy: a report of two cases.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcino | 1995 |
[Medroxyprogesterone acetate for treatment of advanced breast cancers].
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Bre | 2000 |
8 trials available for fluorouracil and Blood Clot
| Article | Year |
|---|---|
Phase II trial of an alternating regimen consisting of first-line mFOLFOX6 plus bevacizumab and FOLFIRI plus bevacizumab for patients with metastatic colorectal cancer: FIREFOX plus bevacizumab trial (KSCC0801).
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Co | 2016 |
Impact of chemotherapy on thrombin generation and on the protein C pathway in breast cancer patients.
Topics: Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Breast Neopla | 2010 |
Neoadjuvant preoperative chemoradiation in patients with pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Mod | 2003 |
A prothrombotic state in breast cancer patients treated with adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation; Breast Neoplasms; Ch | 1996 |
[Adjuvant CMF chemotherapy in patients with breast cancer--results on blood coagulation and fibrinolysis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation; Blood Coagulation Factors; Blood | 1997 |
Hepatic arterial 5-fluorouracil in patients with liver metastases of colorectal cancer: single-centre experience in 145 patients.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Female; Fluor | 2000 |
Results of a prospective randomized study of hepatic artery infusion with 5-fluorouracil versus intravenous 5-fluorouracil in patients with hepatic metastases from colorectal cancer: A Central Oncology Group study.
Topics: Adenocarcinoma; Catheterization; Clinical Trials as Topic; Colonic Neoplasms; Female; Fluorouracil; | 1979 |
The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Dru | 1988 |
55 other studies available for fluorouracil and Blood Clot
| Article | Year |
|---|---|
Long-term survival with sorafenib-based multidisciplinary treatment for Vp4 hepatocellular carcinoma: a case report.
Topics: Carcinoma, Hepatocellular; Cisplatin; Fluorouracil; Humans; Interferons; Liver Neoplasms; Male; Port | 2022 |
Saddle pulmonary embolism with fluorouracil: A case report.
Topics: Adult; Fluorouracil; Humans; Lower Extremity; Male; Pulmonary Embolism; Rivaroxaban; Thrombosis; Tom | 2020 |
[A Case of a Long-Term Survivor Who Underwent Surgical Intervention for Hepatocellular Carcinoma Combined with Tumor Thrombus in the Main Trunkof the Portal Vein].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Fluorouracil; | 2018 |
Acute arterial thrombosis following chemotherapy in a patient with a gastric carcinoma.
Topics: Acute Disease; Adult; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlu | 2013 |
Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Cell Cycle; Colorectal Neopla | 2013 |
Simultaneous thrombosis of superior mesenteric artery and superior mesenteric vein following chemotherapy: MDCT findings.
Topics: Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Docetaxel; Female; Fluorouracil; | 2014 |
[Long-term survival of a patient with hepatocellular carcinoma with portal vein tumor thrombus treated with interferon-α and 5-fluorouracil combination therapy].
Topics: Antimetabolites, Antineoplastic; Antiviral Agents; Carcinoma, Hepatocellular; Chemoembolization, The | 2013 |
[A case of hepatocellular carcinoma (Vp4)-combination therapy prolonged survival in a patient with advanced hepatocellular carcinoma with a tumor thrombus in the portal vein trunk].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Combined Modality | 2013 |
[A case of pathological complete response of advanced rectal cancer with liver metastasis accompanied by tumor thrombus following treatment with bevacizumab/FOLFOX4 chemotherapy].
Topics: Adenocarcinoma; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; B | 2014 |
Tranexamic acid and fibrinogen restore clotting in vitro and in vivo in cardiac thrombus associated hyperfibrinolysis with overt bleedings.
Topics: Adenocarcinoma; Aged; Anemia; Antifibrinolytic Agents; Antineoplastic Combined Chemotherapy Protocol | 2014 |
[Epinephros metastasis of colorectal cancer complicated by tumor thrombosis of inferior vena cava].
Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Adrenalectomy; Antineoplastic Agents; Capecitabine; Colecto | 2015 |
Right atrial thrombus from inferior vena cava after acute cardiotoxicity of 5-fluorouracil.
Topics: Antimetabolites, Antineoplastic; Echocardiography; Female; Fluorouracil; Heart Atria; Heart Diseases | 2008 |
Retrospective cohort study on the safety and efficacy of bevacizumab with chemotherapy for metastatic colorectal cancer patients: the HGCSG0801 study.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclo | 2011 |
Breast cancer chemotherapy induces the release of cell-free DNA, a novel procoagulant stimulus.
Topics: Animals; Antineoplastic Agents; Antithrombin III; Breast Neoplasms; DNA; Doxorubicin; Epirubicin; Fe | 2011 |
The clinical characteristic differences between thrombosis-related edema and lymphedema following radiotherapy or chemoradiotherapy for patients with cervical cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy | 2012 |
Hepatic arterial thrombosis: a critical complication during combination therapy of arterial chemoinfusion and sorafenib.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carc | 2012 |
Chemotherapy associated arterial thrombosis.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Humans; Middle Age | 2002 |
Minidose warfarin prophylaxis for catheter-associated thrombosis in cancer patients: can it be safely associated with fluorouracil-based chemotherapy?
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Catheterization, Central Venous; Drug Interac | 2003 |
Effects of probucol on endothelial damage by 5-fluorouracil.
Topics: Animals; Anticholesteremic Agents; Antimetabolites, Antineoplastic; Arteries; Endothelium, Vascular; | 2003 |
Bevacizumab, bleeding, thrombosis, and warfarin.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticoagulants; Antineoplastic Combined C | 2003 |
[Long-term outcome of advanced hepatocellular carcinoma that received transarterial hepatic chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Female; | 2003 |
[A case of successful treatment of advanced hepatocellular carcinoma with tumor thrombi in the major portal branches and inferior vena cava with combined intraarterial 5-fluorouracil, adriamycin and cisplatin therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Doxorubi | 2003 |
Transient left ventricular and right atrial thrombosis after 5-fluorouracil therapy.
Topics: Abdominal Neoplasms; Adolescent; Carcinoma, Signet Ring Cell; Echocardiography; Fluorouracil; Heart | 2004 |
Bilateral leg amputation following chemoradiation for squamous carcinoma of the anus.
Topics: Aged; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinom | 2004 |
Low-dose warfarin prophylaxis for catheter-associated thrombosis in cancer patients. Can it be safely associated with 5-Fluorouracil-based chemotherapy?
Topics: Anticoagulants; Antimetabolites, Antineoplastic; Catheterization, Central Venous; Catheters, Indwell | 2004 |
[A case of hepatocellular carcinoma with tumor thrombi in the first branch of the portal vein and hepatic vein trunks treated by transcatheter hepatic arterial chemoembolization and hepatic arterial infusion chemotherapy--two years and six months follow-u
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoembolization, | 2005 |
High incidence of INR alteration in gastrointestinal cancer patients treated with mini-dose warfarin and 5-fluorouracil-based regimens.
Topics: Adult; Aged; Anticoagulants; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P | 2006 |
Warfarin-5-FU interactions.
Topics: Anticoagulants; Antimetabolites, Antineoplastic; Drug Interactions; Fluorouracil; Humans; Internatio | 2006 |
Left ventricular thrombus in a patient with esophageal carcinoma.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Diagnosis, Differential; Esophageal Neoplasms; Fluo | 2007 |
Cancer chemotherapy via ambulatory infusion pump.
Topics: Ambulatory Care; Antineoplastic Agents; Doxorubicin; Fluorouracil; Humans; Infusions, Parenteral; Mi | 1983 |
Controlled release of multi-component cytotoxic agents from radiation polymerized composites.
Topics: Delayed-Action Preparations; Doxorubicin; Fluorouracil; In Vitro Techniques; Mitomycins; Polymers; T | 1980 |
[A case of liver metastasis of gastric cancer with portal vein tumor thrombosis responding to chemotherapy with 5-FU and epirubicin].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Epirubicin; Fluorouracil; Huma | 1995 |
Transcatheter chemoembolization of progressive carcinoid liver metastasis.
Topics: Adult; Aged; Carcinoid Tumor; Catheterization; Chemoembolization, Therapeutic; Cisplatin; Doxorubici | 1993 |
Addition of heparin in 5-fluorouracil solution for portal vein infusion has no influence on its stability under clinically relevant conditions.
Topics: Carcinoma; Catheterization, Peripheral; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Stability | 1995 |
Acute arterial thrombosis in a patient with breast cancer after chemotherapy with 5-fluorouracil, doxorubicin, leucovorin, cyclophosphamide, and interleukin-3.
Topics: Acute Disease; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cer | 1994 |
[Chemotherapy-induced thrombotic occlusion of mesenteric arteries--case report and review of the literature].
Topics: Abdomen, Acute; Adrenal Gland Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisp | 1994 |
Successful thrombolysis of SVC thrombosis associated with Hickman lines and continuous infusion chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dox | 1996 |
A novel chemotherapy for advanced hepatocellular carcinoma with tumor thrombosis of the main trunk of the portal vein.
Topics: Aged; alpha-Fetoproteins; Anorexia; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineop | 1997 |
A novel chemotherapy for advanced hepatocellular carcinoma with tumor thrombosis of the main trunk of the portal vein.
Topics: Aged; alpha-Fetoproteins; Anorexia; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineop | 1997 |
A novel chemotherapy for advanced hepatocellular carcinoma with tumor thrombosis of the main trunk of the portal vein.
Topics: Aged; alpha-Fetoproteins; Anorexia; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineop | 1997 |
A novel chemotherapy for advanced hepatocellular carcinoma with tumor thrombosis of the main trunk of the portal vein.
Topics: Aged; alpha-Fetoproteins; Anorexia; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineop | 1997 |
[Thrombotic microangiopathy associated with cancer is an oncologic emergency: a case report].
Topics: Adenocarcinoma; Adult; Anticoagulants; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Ch | 1999 |
Hepatic artery access ports: recognizing and avoiding the problems.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brachytherapy; Catheters, Indwelling; Collateral Circu | 2000 |
Intra-arterial hepatic chemotherapy (IAHC) for liver metastases from colorectal cancer: need of guidelines for catheter positioning, port management, and anti-coagulant therapy.
Topics: Antimetabolites, Antineoplastic; Catheters, Indwelling; Colorectal Neoplasms; Fluorouracil; Hepatic | 2001 |
Acute abdomen during adjuvant chemotherapy: superior mesenteric artery thrombosis associated with CMF chemotherapy.
Topics: Abdomen, Acute; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adju | 2001 |
Mortality associated with irinotecan plus bolus fluorouracil/leucovorin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cardiovascular Diseases; Colorectal Ne | 2002 |
Surgical resection combined with chemotherapy for advanced hepatocellular carcinoma with tumor thrombus: report of 19 cases.
Topics: Adult; Aged; Angiography; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bile Ducts, Extrah | 2002 |
Complications of long term transbrachial hepatic arterial infusion chemotherapy.
Topics: Adolescent; Adult; Aged; Brachial Artery; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusio | 1977 |
Prolonged and continuous percutaneous intra-arterial hepatic infusion chemotherapy in advanced metastatic liver adenocarcinoma from colorectal primary.
Topics: Adenocarcinoma; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusi | 1979 |
Heparinized catheters for long-term intraarterial infusion of 5-fluorouracil in liver metastases.
Topics: Aged; Catheters, Indwelling; Female; Fluorouracil; Heparin; Humans; Infusions, Intra-Arterial; Liver | 1979 |
[Complications related to catheter indwelling in intra-arterial infusion chemotherapy from the standpoint of the route of cannulation].
Topics: Antineoplastic Agents; Aorta; Catheters, Indwelling; Doxorubicin; Femoral Artery; Fluorouracil; Gast | 1992 |
Necrotizing pneumonitis caused by 5-fluorouracil infusion. A complication of a Hickman catheter.
Topics: Aged; Brachiocephalic Veins; Catheters, Indwelling; Fluorouracil; Foreign-Body Migration; Humans; In | 1992 |
Prognostic factors in patients with liver metastases from colorectal carcinoma treated with discontinuous intra-arterial hepatic chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Female; Fluorouracil; Gastrointestinal Diseases; Hep | 1991 |
Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Breast Neoplasms; | 1989 |
Intra-arterial hepatic chemotherapy for metastatic liver from colo-rectal carcinoma origin.
Topics: Adenocarcinoma; Adult; Aged; Colorectal Neoplasms; Female; Floxuridine; Fluorouracil; Hepatic Artery | 1989 |
[Continuous arterial infusion chemotherapy in cancer cases followed as outpatients].
Topics: Ambulatory Care; Antineoplastic Agents; Cisplatin; Fluorouracil; Humans; Infusion Pumps; Infusions, | 1989 |
Palliation of pelvic recurrence of colorectal cancer with intra-arterial 5-fluorouracil and mitomycin.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; C | 1985 |
[Intra-arterial chemotherapy in the treatment of pelvic tumors].
Topics: Angiography; Antineoplastic Agents; Catheterization; Fluorouracil; Humans; Injections, Intra-Arteria | 1971 |