fluorouracil has been researched along with Biliary Tract Diseases in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Biliary Tract Diseases: Diseases in any part of the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The goals of this study of a hepatic arterial infusion (HAI) regimen of alternating floxuridine and 5-fluorouracil were to evaluate the treatment-related toxic effects, the antitumor response rate, and patient survival." | 1.29 | Alternating floxuridine and 5-fluorouracil hepatic arterial chemotherapy for colorectal liver metastases minimizes biliary toxicity. ( Chase, JL; Curley, SA; Davidson, BS; DuBrow, RA; Hohn, DC; Izzo, F; Patt, Y, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miyamoto, S | 1 |
| Umekita, N | 1 |
| Maeshiro, T | 1 |
| Awane, Y | 1 |
| Davidson, BS | 1 |
| Izzo, F | 1 |
| Chase, JL | 1 |
| DuBrow, RA | 1 |
| Patt, Y | 1 |
| Hohn, DC | 1 |
| Curley, SA | 1 |
| Bullen, BR | 1 |
| Giles, GR | 1 |
| Malhotra, A | 1 |
| Bird, GG | 1 |
| Hall, R | 1 |
| Bunch, GA | 1 |
| Brown, GJ | 1 |
| Bateman, JR | 1 |
| Pugh, RP | 1 |
| Cassidy, FR | 1 |
| Marshall, GJ | 1 |
| Irwin, LE | 1 |
| Kovalev, MM | 1 |
| Tanasienko, ID | 1 |
| Govdenko, PF | 1 |
| Geleskul, VF | 1 |
1 trial available for fluorouracil and Biliary Tract Diseases
| Article | Year |
|---|---|
Randomized comparison of melphalan and 5-fluorouracil in the treatment of advanced gastrointestinal cancer.
Topics: Adult; Aged; Biliary Tract Diseases; Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; F | 1976 |
4 other studies available for fluorouracil and Biliary Tract Diseases
| Article | Year |
|---|---|
[Sclerosing cholangitis-induced biliary cyst formation: complication of hepatic artery infusion chemotherapy].
Topics: Adenocarcinoma; Biliary Tract Diseases; Cholangitis, Sclerosing; Cysts; Fluorouracil; Hepatic Artery | 1995 |
Alternating floxuridine and 5-fluorouracil hepatic arterial chemotherapy for colorectal liver metastases minimizes biliary toxicity.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biliar | 1996 |
5-fluorouracil given once weekly: comparison of intravenous and oral administration.
Topics: Adenocarcinoma; Administration, Oral; Biliary Tract Diseases; Breast Neoplasms; Female; Fluorouracil | 1971 |
[Transumbilical drug infusions in the complex treatment of patients with diseases of the abdominal organs].
Topics: Adult; Aged; Anti-Bacterial Agents; Biliary Tract Diseases; Female; Fluorouracil; Gastrointestinal D | 1971 |