fluorouracil has been researched along with Biliary Cirrhosis in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Consequently, secondary biliary cirrhosis developed, requiring orthotopic liver transplantation." | 1.28 | [Ectasing cholangitis and secondary biliary cirrhosis following intra-arterial hepatic chemotherapy. Treatment by liver transplantation]. ( Chapuis, Y; Gaudric, M; Houssin, D; Louvel, A; Pitre, J; Vigouroux, C, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crivellari, D | 1 |
| Cannizzaro, R | 1 |
| Galligioni, E | 1 |
| Valentini, M | 1 |
| Monfardini, S | 1 |
| Castiglione, M | 1 |
| Pitre, J | 1 |
| Houssin, D | 1 |
| Louvel, A | 1 |
| Vigouroux, C | 1 |
| Gaudric, M | 1 |
| Chapuis, Y | 1 |
2 other studies available for fluorouracil and Biliary Cirrhosis
| Article | Year |
|---|---|
Adjuvant therapy for primary breast cancer in a female patient affected by autoimmune liver disease: does it cure breast cancer and primary biliary cirrhosis?
Topics: Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Breast Neoplasms; Chemotherapy, | 1992 |
[Ectasing cholangitis and secondary biliary cirrhosis following intra-arterial hepatic chemotherapy. Treatment by liver transplantation].
Topics: Adenocarcinoma; Adult; Cholangitis, Sclerosing; Female; Fluorouracil; Humans; Infusions, Intra-Arter | 1991 |