fluorouracil has been researched along with Beriberi, Cerebral in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Wernicke's encephalopathy is an acute, neuropsychiatric syndrome resulting from thiamine deficiency, and has significant morbidity and mortality." | 3.75 | A case of Wernicke's encephalopathy following fluorouracil-based chemotherapy. ( Chang, HJ; Cho, IJ; Choi, MY; Lee, KE; Lee, SN; Mun, YC; Nam, EM; Seong, CM; Won, HS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cho, KP | 1 |
| Lee, JS | 1 |
| Seong, JS | 1 |
| Woo, YM | 1 |
| Cho, YJ | 1 |
| Jeong, BJ | 1 |
| Sohn, JH | 1 |
| Kim, SJ | 1 |
| Cho, IJ | 1 |
| Chang, HJ | 1 |
| Lee, KE | 1 |
| Won, HS | 1 |
| Choi, MY | 1 |
| Nam, EM | 1 |
| Mun, YC | 1 |
| Lee, SN | 1 |
| Seong, CM | 1 |
| Guilloton, L | 1 |
| Michaud, A | 1 |
| Potier, V | 1 |
| Le Berre, J | 1 |
| Drouet, A | 1 |
| Felten, D | 1 |
| Kondo, K | 1 |
| Fujiwara, M | 1 |
| Murase, M | 1 |
| Kodera, Y | 1 |
| Akiyama, S | 1 |
| Ito, K | 1 |
| Takagi, H | 1 |
4 other studies available for fluorouracil and Beriberi, Cerebral
| Article | Year |
|---|---|
[Two cases of Wernicke´s encephalopathy that developed during total parenteral nutrition in colon cancer patients treated with 5-fluorouracil-based chemotherapy].
Topics: Adult; Antimetabolites, Antineoplastic; Brain; Colonic Neoplasms; Fluorouracil; Humans; Magnetic Res | 2014 |
A case of Wernicke's encephalopathy following fluorouracil-based chemotherapy.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Female; Fluorouracil; Humans; Magnetic Resonance Ima | 2009 |
[Ataxia and confusion after treatment with 5 Fluorouracile].
Topics: Antimetabolites, Antineoplastic; Ataxia; Colonic Neoplasms; Confusion; Fluorouracil; Humans; Wernick | 2005 |
Severe acute metabolic acidosis and Wernicke's encephalopathy following chemotherapy with 5-fluorouracil and cisplatin: case report and review of the literature.
Topics: Acidosis; Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; F | 1996 |