Page last updated: 2024-10-27

fluorouracil and Benign Frontal Childhood Epilepsy

fluorouracil has been researched along with Benign Frontal Childhood Epilepsy in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"5-Fluorouracil (5-FU) is a mainstay for treating various solid tumours in adults, including digestive and head and neck cancers."1.375-FU-induced neurotoxicity in cancer patients with profound DPD deficiency syndrome: a report of two cases. ( Ciccolini, J; Cordier, PY; Lacarelle, B; Mercier, C; Nau, A; Oliver, M; Peytel, E, 2011)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cordier, PY1
Nau, A1
Ciccolini, J1
Oliver, M1
Mercier, C1
Lacarelle, B1
Peytel, E1

Other Studies

1 other study available for fluorouracil and Benign Frontal Childhood Epilepsy

ArticleYear
5-FU-induced neurotoxicity in cancer patients with profound DPD deficiency syndrome: a report of two cases.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Brain; Dihydropyrimidine Dehydrogenase Deficiency; Electroenc

2011