fluorouracil has been researched along with Barrett Epithelium in 13 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The clinical course of 122 patients with Barrett's carcinoma, who all underwent a neoadjuvant chemotherapy with cisplatin, five fluorouracil and leucovorin and following oesophagectomy, was reviewed." | 3.77 | The amount of neoadjuvant chemotherapy for Barrett's carcinoma does not correlate with long-term survival. ( Friess, H; Knoefel, WT; Schauer, M; Theisen, J, 2011) |
| " 60Co gamma-irradiation or 6MVX-ray with conventional fraction were used for radiotherapy with a total volume dosage of 55-70 Gy." | 1.34 | [Clinical analysis of 108 cases with adenocarcinoma Barretts's esophagus]. ( Han, JQ; Li, XQ; Liang, RX; Liu, Q; Qu, FS; Sun, YH; Yan, TX, 2007) |
| "Columnar-lined or Barrett's esophagus is a premalignant condition." | 1.29 | Is chemotherapy associated with development of Barrett's esophagus? ( Kleibeuker, JH; Peters, FT; Sleijfer, DT; van Imhoff, GW, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, S | 1 |
| Lee, CW | 1 |
| Trevino, JG | 1 |
| Hughes, SJ | 1 |
| Sarosi, GA | 1 |
| Van Der Kraak, L | 1 |
| Goel, G | 1 |
| Ramanan, K | 1 |
| Kaltenmeier, C | 1 |
| Zhang, L | 1 |
| Normolle, DP | 1 |
| Freeman, GJ | 1 |
| Tang, D | 1 |
| Nason, KS | 1 |
| Davison, JM | 1 |
| Luketich, JD | 1 |
| Dhupar, R | 1 |
| Lotze, MT | 1 |
| Schauer, M | 1 |
| Knoefel, WT | 1 |
| Friess, H | 1 |
| Theisen, J | 1 |
| Suto, Y | 1 |
| Tomizawa, N | 1 |
| Andoh, T | 1 |
| Arakawa, K | 1 |
| Kobayashi, K | 1 |
| Sato, H | 1 |
| Sakamoto, K | 1 |
| Itoh, H | 1 |
| Sunose, Y | 1 |
| Takeyoshi, I | 1 |
| Langer, R | 2 |
| Specht, K | 2 |
| Becker, K | 2 |
| Ewald, P | 2 |
| Bekesch, M | 1 |
| Sarbia, M | 2 |
| Busch, R | 2 |
| Feith, M | 2 |
| Stein, HJ | 2 |
| Siewert, JR | 2 |
| Höfler, H | 2 |
| Matono, S | 1 |
| Fujita, H | 1 |
| Sueyoshi, S | 1 |
| Tanaka, T | 1 |
| Yamana, H | 1 |
| Shirouzu, K | 1 |
| Han, JQ | 1 |
| Liu, Q | 1 |
| Liang, RX | 1 |
| Qu, FS | 1 |
| Yan, TX | 1 |
| Sun, YH | 1 |
| Li, XQ | 1 |
| Peters, FT | 1 |
| Sleijfer, DT | 1 |
| van Imhoff, GW | 1 |
| Kleibeuker, JH | 1 |
| Lozac'h, P | 1 |
| Topart, P | 1 |
| Volant, A | 1 |
| Peracchia, A | 1 |
| Bonavina, L | 1 |
| Via, A | 1 |
| Incarbone, R | 1 |
| Sartori, S | 2 |
| Nielsen, I | 2 |
| Indelli, M | 1 |
| Trevisani, L | 2 |
| Pazzi, P | 2 |
| Grandi, E | 1 |
| Malacarne, P | 1 |
13 other studies available for fluorouracil and Barrett Epithelium
| Article | Year |
|---|---|
Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.
Topics: Adenocarcinoma; Apoptosis; Autocrine Communication; Barrett Esophagus; Cell Line, Tumor; Cell Membra | 2013 |
5-Fluorouracil upregulates cell surface B7-H1 (PD-L1) expression in gastrointestinal cancers.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; B7-H1 Antigen; Barrett Esophagus; Biopsy; Cell Line | 2016 |
The amount of neoadjuvant chemotherapy for Barrett's carcinoma does not correlate with long-term survival.
Topics: Aged; Antineoplastic Agents; Barrett Esophagus; Carcinoma; Chemotherapy, Adjuvant; Cisplatin; Cohort | 2011 |
[A case of Barrett's esophageal carcinoma treated with combined therapy].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Chemoradio | 2012 |
Association of pretherapeutic expression of chemotherapy-related genes with response to neoadjuvant chemotherapy in Barrett carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Calm | 2005 |
Long-term survival after three-field lymph-adenectomy for an adenocarcinoma in Barrett's esophagus with metastasis to Virchow's node.
Topics: Abdomen; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Ci | 2006 |
[Prediction of response to neoadjuvant chemotherapy in Barrett's carcinoma by quantitative gene expression analysis].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Cisplatin; DNA Pr | 2004 |
[Clinical analysis of 108 cases with adenocarcinoma Barretts's esophagus].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Comb | 2007 |
Is chemotherapy associated with development of Barrett's esophagus?
Topics: Adult; Antineoplastic Agents; Barrett Esophagus; Breast Neoplasms; Cisplatin; Drug Therapy, Combinat | 1993 |
[Adenocarcinoma of the Barrett esophagus. Apropos of 44 resected cases].
Topics: Actuarial Analysis; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; | 1997 |
Current trends in the surgical treatment of esophageal and cardia adenocarcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Cardia; Chemother | 1999 |
Barrett esophagus after chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil (CMF): an iatrogenic injury?
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Biopsy; Breast Neoplasms; | 1991 |
Barrett's esophagus after antineoplastic chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Cyclophosphamide; Female; Fluorou | 1990 |