fluorouracil has been researched along with Bacterial Eye Infections in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The incidence of late-onset bleb-related endophthalmitis was evaluated retrospectively in 229 consecutive trabeculectomies performed with adjunctive 5-fluorouracil (5-FU) therapy." | 7.68 | Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil. ( Liebmann, JM; Marmor, M; Ritch, R; Sassani, JW; Speaker, M; Wolner, B, 1991) |
| "The incidence of late-onset bleb-related endophthalmitis was evaluated retrospectively in 229 consecutive trabeculectomies performed with adjunctive 5-fluorouracil (5-FU) therapy." | 3.68 | Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil. ( Liebmann, JM; Marmor, M; Ritch, R; Sassani, JW; Speaker, M; Wolner, B, 1991) |
| "The mean follow-up time after treatment for endophthalmitis was 6." | 2.41 | Delayed-onset bleb-associated endophthalmitis: clinical features and visual acuity outcomes. ( Budenz, DL; Flynn, HW; Scott, IU; Song, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parrish, R | 1 |
| Minckler, D | 1 |
| Kasetti, SR | 1 |
| Hugkulstone, CE | 1 |
| Lebowitz, D | 1 |
| Gürses-Ozden, R | 1 |
| Rothman, RF | 1 |
| Liebmann, JM | 2 |
| Tello, C | 1 |
| Ritch, R | 2 |
| Song, A | 1 |
| Scott, IU | 1 |
| Flynn, HW | 1 |
| Budenz, DL | 1 |
| Patitsas, C | 1 |
| Rockwood, EJ | 1 |
| Meisler, DM | 1 |
| McMahon, JT | 1 |
| Wolner, B | 1 |
| Sassani, JW | 1 |
| Speaker, M | 1 |
| Marmor, M | 1 |
1 review available for fluorouracil and Bacterial Eye Infections
| Article | Year |
|---|---|
Delayed-onset bleb-associated endophthalmitis: clinical features and visual acuity outcomes.
Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Bacteria; Endophthalmitis; Eye Infections, Bacteri | 2002 |
5 other studies available for fluorouracil and Bacterial Eye Infections
| Article | Year |
|---|---|
"Late endophthalmitis"--filtering surgery time bomb?
Topics: Antimetabolites; Aqueous Humor; Bacteria; Chemotherapy, Adjuvant; Endophthalmitis; Eye Infections, B | 1996 |
Late infection of a 5-fluorouracil enhanced bleb following systemic chemotherapy.
Topics: Aged; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Eye Infections, Bacterial; Fl | 2000 |
Late-onset bleb-related panophthalmitis with orbital abscess caused by Pseudomonas stutzeri.
Topics: Abscess; Aged; Eye Enucleation; Eye Infections, Bacterial; Fluorouracil; Humans; Male; Orbital Disea | 2001 |
Infectious crystalline keratopathy occurring in an eye subsequent to glaucoma filtering surgery with postoperative subconjunctival 5-fluorouracil.
Topics: Chronic Disease; Eye Infections, Bacterial; Female; Fluorouracil; Glaucoma, Angle-Closure; Humans; K | 1991 |
Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Child; Child, Preschool; Endophth | 1991 |