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fluorouracil and B. burgdorferi Infection

fluorouracil has been researched along with B. burgdorferi Infection in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Barbour-Stoenner-Kelly (BSK) II medium containing fosfomycin, 5-fluorouracil, trimethoprim and sulfamethoxazole was evaluated for the selective isolation of the Borrelia species responsible for Lyme disease and relapsing fever."3.68Evaluation of agents for use in medium for selective isolation of Lyme disease and relapsing fever Borrelia species. ( Konishi, H; Morshed, MG; Nakazawa, T; Nishimura, T, 1993)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morshed, MG1
Konishi, H1
Nishimura, T1
Nakazawa, T1

Other Studies

1 other study available for fluorouracil and B. burgdorferi Infection

ArticleYear
Evaluation of agents for use in medium for selective isolation of Lyme disease and relapsing fever Borrelia species.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1993, Volume: 12, Issue:7

    Topics: Bacteriological Techniques; Borrelia; Culture Media; Drug Combinations; Fluorouracil; Fosfomycin; Ly

1993