Page last updated: 2024-10-27

fluorouracil and Autoimmune Disease

fluorouracil has been researched along with Autoimmune Disease in 6 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Vitiligo is characterized by depigmentation in large or small areas of the skin."1.27Vitiligo. ( Dunn, JF, 1986)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BERENBAUM, MC1
BROWN, IN1
VONLEDEN, H1
SCHIFF, M1
Lemperle, G1
Rullan, PP1
Gauthier-Hazan, N1
Crivellari, D1
Cannizzaro, R1
Galligioni, E1
Valentini, M1
Monfardini, S1
Castiglione, M1
Dunn, JF1

Reviews

1 review available for fluorouracil and Autoimmune Disease

ArticleYear
Avoiding and treating dermal filler complications.
    Plastic and reconstructive surgery, 2006, Volume: 118, Issue:3 Suppl

    Topics: Adipose Tissue; Adrenal Cortex Hormones; Animals; Autoimmune Diseases; Biocompatible Materials; Catt

2006

Other Studies

5 other studies available for fluorouracil and Autoimmune Disease

ArticleYear
DOSE-RESPONSE RELATIONSHIPS FOR AGENTS INHIBITING THE IMMUNE RESPONSE.
    Immunology, 1964, Volume: 7

    Topics: Allergy and Immunology; Antibody Formation; Antineoplastic Agents; Autoimmune Diseases; Cyclophospha

1964
ANTIMETABOLITE THERAPY IN MIDLINE LETHAL GRANULOMA.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1964, Volume: 80

    Topics: Antimetabolites; Autoimmune Diseases; DNA; Drug Therapy; Fluorouracil; Granuloma; Granuloma, Lethal

1964
Adjuvant therapy for primary breast cancer in a female patient affected by autoimmune liver disease: does it cure breast cancer and primary biliary cirrhosis?
    Tumori, 1992, Dec-31, Volume: 78, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Breast Neoplasms; Chemotherapy,

1992
[Delayed post-transfusional hemolysis, leukemoid syndrome, autoimmune hemolytic anemia. Coordinating Committee for the Specific Study of Anemias under the chairmanship of H. Rochant].
    Nouvelle revue francaise d'hematologie, 1987, Volume: 29, Issue:6

    Topics: Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Colonic Neoplasms; Female; Flu

1987
Vitiligo.
    American family physician, 1986, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Autoimmune Diseases; Child; Child, Preschool; Diagnosis, Differential; Female; Fl

1986