fluorouracil has been researched along with Atypical Chronic Myeloid Leukemia in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahon, FX | 1 |
| Pigeonnier-Lagarde, V | 1 |
| Chahine, H | 1 |
| Barbot, C | 1 |
| Jazwiec, B | 1 |
| Ripoche, J | 1 |
| Reiffers, J | 1 |
1 other study available for fluorouracil and Atypical Chronic Myeloid Leukemia
| Article | Year |
|---|---|
Ex vivo cytokine expansion of peripheral blood 5-fluorouracil-treated CD34-positive chronic myeloid leukaemia cells increases the selection of Ph-negative cells.
Topics: Antigens, CD34; Cell Division; Cytokines; Fluorouracil; Fusion Proteins, bcr-abl; Humans; In Situ Hy | 1997 |