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fluorouracil and Atypical Chronic Myeloid Leukemia

fluorouracil has been researched along with Atypical Chronic Myeloid Leukemia in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mahon, FX1
Pigeonnier-Lagarde, V1
Chahine, H1
Barbot, C1
Jazwiec, B1
Ripoche, J1
Reiffers, J1

Other Studies

1 other study available for fluorouracil and Atypical Chronic Myeloid Leukemia

ArticleYear
Ex vivo cytokine expansion of peripheral blood 5-fluorouracil-treated CD34-positive chronic myeloid leukaemia cells increases the selection of Ph-negative cells.
    British journal of haematology, 1997, Volume: 98, Issue:2

    Topics: Antigens, CD34; Cell Division; Cytokines; Fluorouracil; Fusion Proteins, bcr-abl; Humans; In Situ Hy

1997