fluorouracil has been researched along with Atherosclerosis in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tumor control, reflected in lower CEA, resulted in suppression of the acute phase response and generally in favorable effects on laboratory parameters indicative of risk factors of atherosclerosis, including lower homocysteine concentrations, and lower total and LDL cholesterol." | 3.75 | Serum homocysteine, cholesterol, retinol, alpha-tocopherol, glycosylated hemoglobin and inflammatory response during therapy with bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin. ( Hyspler, R; Kalábová, H; Kasparová, M; Krcmová, L; Malírová, E; Melichar, B; Melicharová, K; Pecka, M; Solichová, D, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kurniadi, I | 1 |
| Yamada, D | 1 |
| Wirya, AY | 1 |
| Norimatsu, Y | 1 |
| Kuzumi, A | 1 |
| Ogaki, J | 1 |
| Takahashi, N | 1 |
| Sato, S | 1 |
| Abaci, HE | 1 |
| Shen, YI | 1 |
| Tan, S | 1 |
| Gerecht, S | 1 |
| Melichar, B | 1 |
| Kalábová, H | 1 |
| Krcmová, L | 1 |
| Kasparová, M | 1 |
| Malírová, E | 1 |
| Melicharová, K | 1 |
| Pecka, M | 1 |
| Hyspler, R | 1 |
| Solichová, D | 1 |
| Jensen, SA | 1 |
| Sørensen, JB | 1 |
4 other studies available for fluorouracil and Atherosclerosis
| Article | Year |
|---|---|
Trousseau syndrome associated with cutaneous squamous cell carcinoma.
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Atherosclerosis; Carcinoma, Squamous Cell; Carot | 2018 |
Recapitulating physiological and pathological shear stress and oxygen to model vasculature in health and disease.
Topics: Animals; Atherosclerosis; Capillary Permeability; Endothelial Cells; Endothelium, Vascular; Fluorour | 2014 |
Serum homocysteine, cholesterol, retinol, alpha-tocopherol, glycosylated hemoglobin and inflammatory response during therapy with bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin.
Topics: Adult; Aged; alpha-Tocopherol; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopla | 2009 |
Risk factors and prevention of cardiotoxicity induced by 5-fluorouracil or capecitabine.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Atherosclerosis; Capecitabine; | 2006 |