fluorouracil has been researched along with Ataxia of Gait in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Capecitabine is an oral fluoropyrimidine used for cancer treatment." | 1.32 | Capecitabine-related neurotoxicity presenting as trismus. ( Couch, LS; Groteluschen, DL; Mulkerin, DL; Stewart, JA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Couch, LS | 1 |
| Groteluschen, DL | 1 |
| Stewart, JA | 1 |
| Mulkerin, DL | 1 |
1 other study available for fluorouracil and Ataxia of Gait
| Article | Year |
|---|---|
Capecitabine-related neurotoxicity presenting as trismus.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Central Nervous System; Confusion; Deoxycytidine; Dia | 2003 |